Data / Research funding / Macular Degeneration

Macular Degeneration: 324 NIH awards ($410.7M) to 134 organizations

Name: NIH and NSF awards on Macular Degeneration
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

324 NIH awards ($410.7M) in the NIH spending category Macular Degeneration, to 134 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Get awards on Macular Degeneration Watch Macular Degeneration

Topic: NIH spending category

Awards

324 awards in the window.

Award	Agency	Institute or division	Fiscal year	Amount in window	Start	End	Principal investigator	Source
DRCR Retina Network	NIH	National Eye Institute	2021 to 2025	$43,226,123	September 30, 2002	December 31, 2028	GLASSMAN, ADAM R	reporter.nih.gov
EO14042 DEVELOPMENT, STATISTICAL DESIGN, MONITORING AND COORDINATION OF VISION CLINICAL TRIALS AND EPIDEMIOLOGY RESEARCH	NIH	Office of the Director, National Institutes of Health	2022 to 2025	$25,277,032	November 1, 2021	October 31, 2026	MENEZES, SUPRIYA	reporter.nih.gov
Therapeutic gene editing and multimodal imaging in juvenile macular degeneration	NIH	National Eye Institute	2021 to 2024	$8,710,741	June 1, 2020	May 31, 2026	TSANG, STEPHEN H	reporter.nih.gov
IGF::OT::IGFEMMES NEIS-V	NIH	Office of the Director, National Institutes of Health	2021	$7,315,897	November 1, 2016	October 31, 2021	HAMMEL, KERI	reporter.nih.gov
Unraveling the molecular pathology of retinal degeneration through single cell genomics	NIH	National Eye Institute	2021 to 2025	$3,347,817	June 1, 2021	May 31, 2027	AYYAGARI, RADHA	reporter.nih.gov
Soft drusen in rhesus macaques as a nonhuman primate model of early age-related macular degeneration	NIH	National Eye Institute	2021 to 2025	$3,241,037	January 1, 2021	December 31, 2026	YIU, GLENN	reporter.nih.gov
Retinal Circuitry	NIH	National Eye Institute	2021 to 2025	$3,035,626	January 1, 2019	March 31, 2030	JONES, BRYAN WILLIAM	reporter.nih.gov
Mechanisms of RPE dysfunction in macular degenerations: role of intracellular complement activation	NIH	National Eye Institute	2021 to 2024	$2,920,740	May 1, 2020	April 30, 2025	LAKKARAJU, APARNA	reporter.nih.gov
A Model for Predicting 2-Year Risk of Incident Late Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2025	$2,920,229	May 1, 2021	July 31, 2027	BHUIYAN, ALAUDDIN	reporter.nih.gov
Genomic Sequencing of Japanese Macaques to Enhance NHP Model Discovery	NIH	Office of the Director, National Institutes of Health	2021 to 2023	$2,892,711	July 1, 2016	June 30, 2025	FERGUSON, BETSY M	reporter.nih.gov
Translational Research for Retinal Degeneration Therapies	NIH	National Eye Institute	2021 to 2024	$2,827,259	September 30, 2007	August 31, 2025	BELTRAN, WILLIAM A.	reporter.nih.gov
Functionally Validated Structural Endpoints for Early AMD	NIH	National Eye Institute	2021 to 2023	$2,660,293	May 1, 2019	February 28, 2026	OWSLEY, CYNTHIA	reporter.nih.gov
Phase1/2a Clinical Trial of RPESC-derived RPE Transplantation as Therapy for Non-exudative Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2024	$2,549,156	September 30, 2020	September 29, 2025	STERN, JEFFREY H	reporter.nih.gov
Molecular Genetics of Age-Dependent Retinal Degeneration	NIH	National Eye Institute	2021 to 2025	$2,527,132	August 1, 2012	July 31, 2028	IKEDA, AKIHIRO	reporter.nih.gov
Mitochondrial defects in the retinal pigment epithelium and the CFH risk allele for age-related macular degeneration	NIH	National Eye Institute	2022 to 2025	$2,526,222	April 1, 2018	June 30, 2026	FERRINGTON, DEBORAH ANN	reporter.nih.gov
OCT Angiography for Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2025	$2,521,643	September 1, 2014	May 31, 2027	JIA, YALI	reporter.nih.gov
Membrane Protein Effectors of Pathogen Interactions With Host	NIH	National Institute of General Medical Sciences	2022 to 2025	$2,510,135	June 1, 2016	May 31, 2026	MARASSI, FRANCESCA M	reporter.nih.gov
FGF and hyaluronan-mediated alterations in epithelial-mesenchymal transition and metabolism of RPE cells in Sorsby Fundus Dystrophy.	NIH	National Eye Institute	2021 to 2024	$2,497,198	April 1, 2017	March 31, 2026	ANAND-APTE, BELA	reporter.nih.gov
Connecting AMD SNPs to Functions Using Allele-specific Interactions	NIH	National Eye Institute	2021 to 2025	$2,425,296	January 1, 2021	November 30, 2026	ZACK, DONALD J.	reporter.nih.gov
Slit2-ROBO signaling in pericytes and myeloid cells controls vascular development and ocular neovascular disease	NIH	National Heart, Lung, and Blood Institute	2022 to 2025	$2,400,609	July 1, 2015	January 31, 2026	EICHMANN, ANNE CHRISTINE	reporter.nih.gov
Epidemiology of Biomarkers of AMD Progression	NIH	National Eye Institute	2021 to 2025	$2,396,992	September 30, 2021	August 31, 2027	SADDA, SRINIVAS R	reporter.nih.gov
Metabolomics a Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2025	$2,361,511	March 1, 2020	July 31, 2030	HUSAIN, DEEBA	reporter.nih.gov
Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss	NIH	National Eye Institute	2021 to 2024	$2,340,705	March 1, 2021	February 28, 2026	VISSCHER, KRISTINA	reporter.nih.gov
Characterizing Human RPE Cell Proliferation to Advance Endogenous Regeneration	NIH	National Eye Institute	2021 to 2024	$2,286,488	February 1, 2021	November 30, 2025	TEMPLE, SALLY	reporter.nih.gov
Metabolic dysfunction from ECM remodeling in diseases of human RPE	NIH	National Eye Institute	2022 to 2025	$2,274,411	September 1, 2022	June 30, 2027	CHAO, JENNIFER RAYMING	reporter.nih.gov
Delineating the role of TIMP3 in macular degeneration	NIH	National Eye Institute	2021 to 2025	$2,268,028	September 30, 2017	May 31, 2027	SINGH, RUCHIRA	reporter.nih.gov
Complement factor H modulates lipoprotein clearance in AMD	NIH	National Eye Institute	2021 to 2024	$2,266,452	August 1, 2020	July 31, 2025	BOWES RICKMAN, CATHERINE	reporter.nih.gov
Deconstructing and Modeling the Single Cell Architecture of the Age-Related Macular Degeneration Retina and RPE/Choroid	NIH	National Eye Institute	2021 to 2024	$2,163,658	September 1, 2020	June 30, 2024	STAMBOLIAN, DWIGHT EDWARD	reporter.nih.gov
Theranostics of Photoreceptor-RPE-Choroid Neurovascular Unit in Eye Diseases:	NIH	National Eye Institute	2021 to 2025	$2,128,279	February 1, 2017	February 28, 2027	ZAWADZKI, ROBERT J	reporter.nih.gov
DICER1 deficiency in aberrant chorioretinal neovascularization	NIH	National Eye Institute	2021 to 2024	$2,101,749	June 1, 2021	May 31, 2025	GELFAND, BRADLEY DAVID	reporter.nih.gov
Identifying the cause for photoreceptor-mediated retinal-pigmented epithelium atrophy	NIH	National Eye Institute	2021 to 2025	$2,081,188	June 1, 2021	May 31, 2027	PUNZO, CLAUDIO	reporter.nih.gov
A hyperspectral approach to RPE fluorophores in AMD	NIH	National Eye Institute	2022 to 2025	$2,071,603	July 1, 2017	April 30, 2027	CURCIO, CHRISTINE A	reporter.nih.gov
Assessment of the Complement Pathway in a RPE/choroid Tissue Chip	NIH	National Eye Institute	2024 to 2025	$2,066,956	September 1, 2024	April 30, 2028	ROHRER, BAERBEL	reporter.nih.gov
Muller cell activation and remodeling in AMD.	NIH	National Eye Institute	2021 to 2025	$2,034,594	February 1, 2021	December 31, 2025	EDWARDS, MALIA MICHELLE	reporter.nih.gov
RORalpha mediates chronic subretinal inflammation associated with AMD	NIH	National Eye Institute	2022 to 2025	$2,030,820	December 2, 2014	May 31, 2027	CHEN, JING	reporter.nih.gov
International Advancing genomics through the AMD Genomics Consortium (IAMDGC)	NIH	National Eye Institute	2021 to 2024	$2,023,778	April 1, 2012	June 30, 2026	HAINES, JONATHAN L	reporter.nih.gov
Electronic photoreceptors for restoration of sight in retinal degeneration	NIH	National Eye Institute	2023 to 2025	$2,018,333	September 1, 2023	April 30, 2028	PALANKER, DANIEL V	reporter.nih.gov
Use of Correlated Data Methods in Ophthalmology	NIH	National Eye Institute	2022 to 2025	$2,006,644	September 1, 2013	December 31, 2026	ROSNER, BERNARD A	reporter.nih.gov
The role of Angiopoietin-TEK signaling in polypoidal choroidal vasculopathy	NIH	National Eye Institute	2021 to 2025	$2,004,347	June 1, 2021	May 31, 2027	THOMSON, BENJAMIN R.	reporter.nih.gov
Mechanistic basis of sexual dimorphism in antigen-independent IgG1 angiogenesis regulation	NIH	National Heart, Lung, and Blood Institute	2023 to 2025	$1,999,156	April 1, 2023	February 28, 2027	GELFAND, BRADLEY DAVID	reporter.nih.gov
Developing photoreceptor repair for macular degeneration therapy.	NIH	National Eye Institute	2021 to 2025	$1,986,308	September 30, 2021	July 31, 2026	SINGH, MANDEEP	reporter.nih.gov
Mitochondrial pyruvate transport in retinal health and disease	NIH	National Eye Institute	2021 to 2024	$1,980,105	January 1, 2021	November 30, 2025	DU, JIANHAI	reporter.nih.gov
Stimulation of Retinal Regeneration	NIH	National Eye Institute	2021 to 2025	$1,969,184	April 1, 2011	April 30, 2027	REH, THOMAS A	reporter.nih.gov
Optimizing Models of Non-Coding Genetic Risk in Age-Related Macular Degeneration	NIH	National Eye Institute	2022 to 2025	$1,969,000	March 1, 2022	February 28, 2026	CHERRY, TIMOTHY JOEL	reporter.nih.gov
Choriocapillaris Protection and Replacement in AMD	NIH	National Eye Institute	2021 to 2025	$1,966,287	August 1, 2014	December 31, 2027	MULLINS, ROBERT FOSTER	reporter.nih.gov
Identifying mechanistic pathways underlying RPE pathogenesis in models of pattern dystrophy	NIH	National Eye Institute	2023 to 2025	$1,960,269	June 1, 2023	January 31, 2027	NAGGERT, JUERGEN K.	reporter.nih.gov
RPE Messengers, Transcription and Photoreceptor Renewal	NIH	National Eye Institute	2021 to 2025	$1,960,138	March 1, 1984	April 30, 2029	BAZAN, NICOLAS G.	reporter.nih.gov
Quantitative multimodal retinal imaging	NIH	National Eye Institute	2021 to 2024	$1,955,816	July 1, 2021	April 30, 2026	JIAO, SHULIANG	reporter.nih.gov
Molecular Genetics of a Complement Factor H homolog	NIH	National Eye Institute	2021 to 2025	$1,919,663	September 30, 2021	July 31, 2026	VOGEL, BRUCE E	reporter.nih.gov
Biochemistry and Pharmacology of the Macular Carotenoids	NIH	National Eye Institute	2021 to 2025	$1,908,354	August 1, 1997	April 30, 2027	BERNSTEIN, PAUL STEVEN	reporter.nih.gov
Distinguishing normal aging from age-related macular degeneration at the level of single cells in the living human eye	NIH	National Eye Institute	2021 to 2024	$1,890,092	June 1, 2020	May 31, 2025	ROSSI, ETHAN A	reporter.nih.gov
Proline metabolism in retinal health	NIH	National Eye Institute	2021 to 2025	$1,888,600	June 1, 2021	March 31, 2027	DU, JIANHAI	reporter.nih.gov
Polypharmacological approach to treatment of Stargardt disease	NIH	National Eye Institute	2023 to 2025	$1,883,416	March 1, 2023	February 28, 2027	PETRUKHIN, KONSTANTIN	reporter.nih.gov
Cytosolic SINE retrotransposable element cDNA and mitochondrial DNA in aging retina	NIH	National Institute on Aging	2023 to 2025	$1,872,610	August 15, 2023	April 30, 2028	AMBATI, JAYAKRISHNA	reporter.nih.gov
Transformational next generation high affinity trispecific fab protein to address unmet needs in Ophthalmology	NIH	National Eye Institute	2024 to 2025	$1,867,066	September 30, 2024	July 31, 2027	XU, LI	reporter.nih.gov
Inflammatory cells of choroid: a therapeutic target in AMD	NIH	National Eye Institute	2021 to 2024	$1,859,673	September 1, 2006	May 31, 2025	EDWARDS, MALIA MICHELLE	reporter.nih.gov
Dysregulation of Wnt signaling in subretinal fibrosis in AMD	NIH	National Eye Institute	2021 to 2025	$1,852,848	September 1, 2021	May 31, 2027	TAKAHASHI, YUSUKE	reporter.nih.gov
Targeting lysosome/RPE heterogeneity in AMD pathobiology as a novel therapy	NIH	National Eye Institute	2021 to 2024	$1,847,791	June 1, 2021	July 1, 2024	SINHA, DEBASISH	reporter.nih.gov
Nuclear receptor driven mechanisms in aging and AMD	NIH	National Eye Institute	2021 to 2024	$1,836,395	August 1, 2021	July 31, 2025	MALEK, GOLDIS	reporter.nih.gov
Immunologic Determinants of Age-Related Macular Degeneration (AMD)	NIH	National Eye Institute	2021 to 2024	$1,820,707	March 1, 2016	August 31, 2025	JABS, DOUGLAS A	reporter.nih.gov
Novel Long-Acting Inhibitors of Vascular Endothelial Growth Factor (VEGF) for Treatment of Intraocular Vascular Disorders	NIH	National Eye Institute	2021 to 2024	$1,817,758	April 1, 2020	March 31, 2026	FERRARA, NAPOLEONE	reporter.nih.gov
The Human Foveal Connectome	NIH	National Eye Institute	2021 to 2024	$1,816,440	February 1, 2020	January 31, 2026	DACEY, DENNIS MICHAEL	reporter.nih.gov
Cholesterol Homeostasis in the Retina	NIH	National Eye Institute	2021 to 2024	$1,773,831	September 1, 2007	March 31, 2026	PIKULEVA, IRINA A	reporter.nih.gov
Inhibiting Neovascularization and Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration	NIH	National Eye Institute	2023 to 2025	$1,768,396	July 1, 2023	June 30, 2028	ZHU, WEIQUAN (WENDY)	reporter.nih.gov
Patterning Genes in Retinal Development	NIH	National Eye Institute	2021 to 2025	$1,759,668	June 1, 1998	May 31, 2029	STENKAMP, DEBORAH L	reporter.nih.gov
The role of epigenetics in RPE heterogeneity with early AMD	NIH	National Eye Institute	2022 to 2025	$1,750,941	June 1, 2022	May 31, 2026	HANDA, JAMES T	reporter.nih.gov
Using hiPSCs to develop physiologically-relevant outer retina tissue mimetics	NIH	National Eye Institute	2022 to 2024	$1,738,353	September 30, 2022	August 31, 2025	SINGH, RUCHIRA	reporter.nih.gov
Full Field OCT for Cellular Level Structural and Functional Retinal Imaging	NIH	National Eye Institute	2021 to 2023	$1,711,572	September 1, 2020	August 31, 2025	DOBLE, NATHAN	reporter.nih.gov
Maximizing Visual Potential in Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2024	$1,697,377	March 1, 2017	February 28, 2026	VERGHESE, PREETI	reporter.nih.gov
Novel Optical Diagnostics with Optical Coherence Tomography	NIH	National Eye Institute	2021 to 2024	$1,685,086	September 1, 1985	March 31, 2026	FUJIMOTO, JAMES G	reporter.nih.gov
Modeling and mechanistic investigation of a novel dry AMD mouse model with CLIC4 deleted in RPE	NIH	National Eye Institute	2021 to 2024	$1,682,288	September 1, 2021	May 31, 2026	SUNG, CHING-HWA	reporter.nih.gov
Proangiogenic M2-type macrophages and choroidal neovascularization	NIH	National Eye Institute	2022 to 2025	$1,679,081	September 1, 2022	July 31, 2026	MARNEROS, ALEXANDER GEORG	reporter.nih.gov
OCT-based functional biomarkers for degenerative diseases of the photoreceptor-RPE-choroid neurovascular unit	NIH	National Eye Institute	2023 to 2025	$1,673,621	September 30, 2023	June 30, 2028	JONNAL, RAVI S.	reporter.nih.gov
True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence Tomography	NIH	National Eye Institute	2021 to 2023	$1,664,971	August 1, 2020	July 31, 2025	SRINIVASAN, VIVEK JAY	reporter.nih.gov
Multi-specific long-acting antibodies for the treatment of retinal neovascular diseases	NIH	National Eye Institute	2024 to 2025	$1,657,994	September 1, 2019	February 28, 2027	TRAN, HIEP T	reporter.nih.gov
Elucidating the mechanism of erythropoietin (EPO) in mitigating Dry-AMD pathophysiology	NIH	National Eye Institute	2022 to 2025	$1,649,920	September 1, 2022	May 31, 2027	BISWAL, MANAS R	reporter.nih.gov
Imaging of Retinal Hydroxyapatite as an Early Screen for AMD	NIH	National Eye Institute	2021 to 2023	$1,648,491	June 1, 2020	May 31, 2025	THOMPSON, RICHARD BLAIR	reporter.nih.gov
Damage-Free, Ultrasonic Cell Isolation from Retinal Pigment Epithelium (RPE) Monolayers	NIH	National Eye Institute	2023 to 2025	$1,636,690	August 1, 2023	February 28, 2027	KIM, EUN SOK	reporter.nih.gov
MMP-9 based immune-driven mechanisms of neovascular AMD	NIH	National Eye Institute	2023 to 2025	$1,621,317	September 1, 2023	January 31, 2027	SOHN, ELLIOTT H	reporter.nih.gov
Targeting the inflammatory response in age-related macular degeneration	NIH	National Eye Institute	2022 to 2025	$1,612,188	September 30, 2022	August 31, 2027	HAFLER, BRIAN P	reporter.nih.gov
Dysregulation of PPARα in RPE degeneration	NIH	National Eye Institute	2023 to 2025	$1,610,155	September 30, 2023	April 30, 2028	MA, JIAN-XING JAY	reporter.nih.gov
Impact of Lipofuscin in Retinal Pigment Epithelial Cells	NIH	National Eye Institute	2021 to 2024	$1,607,850	May 1, 2000	June 30, 2025	SPARROW, JANET RUTHE	reporter.nih.gov
"Myeloid PFKFB3 in subretinal fibrosis"	NIH	National Eye Institute	2022 to 2025	$1,601,328	April 1, 2022	February 28, 2027	CALDWELL, RUTH B	reporter.nih.gov
Biomarkers of Systemic Inflammation in Intermediate Age-Related Macular Degeneration	NIH	National Eye Institute	2021 to 2024	$1,592,998	May 1, 2021	April 30, 2026	LYNCH, ANNE M.	reporter.nih.gov
The IL-6 Induced Retinal Iron Sequestration Response	NIH	National Eye Institute	2021 to 2023	$1,585,434	June 1, 2019	May 31, 2024	DUNAIEF, JOSHUA L	reporter.nih.gov
Investigating fundamental properties and clinical applications of the optoretinogram	NIH	National Eye Institute	2022 to 2025	$1,567,232	February 1, 2022	January 31, 2027	JONNAL, RAVI S.	reporter.nih.gov
Functional Analysis of Complement Variants in a Genotyped iPSC Epithelial Cell Model System	NIH	National Institute of Allergy and Infectious Diseases	2024 to 2025	$1,563,098	December 4, 2023	October 31, 2028	STAMBOLIAN, DWIGHT EDWARD	reporter.nih.gov
Pigment Regeneration Mechanisms in the Human Retina	NIH	National Eye Institute	2021 to 2024	$1,561,915	September 30, 2020	June 30, 2025	VINBERG, FRANS	reporter.nih.gov
Molecular Studies of the Choriocapillaris in AMD	NIH	National Eye Institute	2022 to 2025	$1,545,000	January 1, 2022	November 30, 2026	MULLINS, ROBERT FOSTER	reporter.nih.gov
A Next Generation Outer Retinal Microphysiological System	NIH	National Eye Institute	2022 to 2025	$1,545,000	May 1, 2022	April 30, 2026	TUCKER, BUDD A	reporter.nih.gov
GRP78 signaling and retinal angiogenesis	NIH	National Eye Institute	2023 to 2025	$1,533,198	August 1, 2023	February 28, 2027	RAO, GADIPARTHI N	reporter.nih.gov
Neural Control of Choroidal Function	NIH	National Eye Institute	2023 to 2025	$1,517,907	September 1, 2023	April 30, 2028	GAMLIN, PAUL DOUGLAS	reporter.nih.gov
Integrin-binding Peptide for Ocular Neovascularization and Macular Edema: Molecular Mechanism of Action	NIH	National Eye Institute	2021 to 2025	$1,511,062	March 1, 2019	June 30, 2028	GREEN, JORDAN	reporter.nih.gov
Ambient light activatable opsin based therapy for age-related macular degeneration	NIH	National Eye Institute	2021 to 2022	$1,487,322	September 1, 2015	February 29, 2024	MOHANTY, SAMARENDRA KUMAR	reporter.nih.gov
Cellular and molecular mechanisms of AIM2 and NLRP3 inflammasome activation in age-related macular degeneration	NIH	National Eye Institute	2023 to 2025	$1,486,400	February 1, 2023	January 31, 2027	MARNEROS, ALEXANDER GEORG	reporter.nih.gov
Mitochondrial-Targeted Therapy for Macular Degeneration	NIH	National Eye Institute	2023 to 2024	$1,485,618	June 1, 2023	May 31, 2026	COUSINS, SCOTT WILLIAM	reporter.nih.gov
The Impact of Non-Exudative Type 1 Macular Neovascularization (MNV) on Age-related Macular Degeneration (AMD) Progression	NIH	National Eye Institute	2022 to 2025	$1,481,000	September 1, 2022	June 30, 2027	FLECKENSTEIN, MONIKA	reporter.nih.gov
Molecular mechanism underlying late-onset retinal/macular degeneration	NIH	National Eye Institute	2021 to 2023	$1,478,260	September 1, 2020	June 30, 2025	AYYAGARI, RADHA	reporter.nih.gov
Endothelial Transmigration in Neovascular Age-related Macular Degeneration	NIH	National Eye Institute	2023 to 2025	$1,476,478	April 1, 2007	March 31, 2026	HARTNETT, MARY ELIZABETH RUTH	reporter.nih.gov
Remapping the Visual Field to Aid Reading with Central Scotomas	NIH	National Eye Institute	2021 to 2024	$1,467,642	July 1, 2020	June 30, 2026	ENGEL, STEPHEN A.	reporter.nih.gov
Elastase and Elastin Peptide Activity in Age-Related Macular Degeneration	NIH	National Eye Institute	2021 to 2024	$1,467,451	January 1, 2020	December 31, 2025	ROHRER, BAERBEL	reporter.nih.gov
Role of ARMS2 mutations in age-related macular degeneration	NIH	National Eye Institute	2024 to 2025	$1,450,878	June 1, 2024	May 31, 2029	NISHINA, PATSY M	reporter.nih.gov
Plasmonic Retinal Prosthesis	NIH	National Eye Institute	2021 to 2023	$1,423,769	September 1, 2019	August 31, 2025	LEE, JONGHWAN	reporter.nih.gov
Advancing the small molecule drug candidate with dual specificity as a therapy for dry AMD	NIH	National Eye Institute	2024 to 2025	$1,418,507	July 1, 2024	June 30, 2027	PETRUKHIN, KONSTANTIN	reporter.nih.gov
Use of systems pharmacology to prevent rod and cone photoreceptor degeneration	NIH	National Eye Institute	2021	$1,405,643	July 1, 2017	March 31, 2022	PALCZEWSKI, KRZYSZTOF	reporter.nih.gov
Deciphering the role of osteopontin in the aging eye and age-related macular degeneration	NIH	National Eye Institute	2023 to 2025	$1,374,145	July 1, 2023	June 30, 2027	MALEK, GOLDIS	reporter.nih.gov
Visual acuity and functional measurements in the aging eye	NIH	National Eye Institute	2022 to 2023	$1,359,669	September 1, 2019	April 30, 2026	GAST, THOMAS J.	reporter.nih.gov
Metabolic reprogramming of endothelial precursor cells in subretinal fibrosis	NIH	National Eye Institute	2023 to 2025	$1,355,682	September 30, 2023	June 30, 2028	CAI, JIYANG	reporter.nih.gov
Regulation of vitamin A metabolism in the eye	NIH	National Eye Institute	2021 to 2023	$1,353,752	August 1, 2014	December 31, 2024	GOLCZAK, MARCIN BERNARD	reporter.nih.gov
Targeting the Ref-1 signaling node for treating ocular neovascularization	NIH	National Eye Institute	2021 to 2023	$1,350,030	August 1, 2020	June 30, 2025	KELLEY, MARK R.	reporter.nih.gov
Paradoxical role of anti-VEGF therapy in subretinal fibrosis of wet AMD	NIH	National Eye Institute	2024 to 2025	$1,340,992	September 1, 2024	May 31, 2028	LI, WEI	reporter.nih.gov
Targeted Nano-enhanced Optical Delivery of opsin for dry-AMD therapy	NIH	National Eye Institute	2021 to 2022	$1,334,846	June 1, 2020	May 31, 2025	MOHANTY, SAMARENDRA KUMAR	reporter.nih.gov
Adenosine receptor 2A in subretinal fibrosis	NIH	National Eye Institute	2022 to 2024	$1,313,253	May 1, 2022	August 11, 2024	HUO, YUQING	reporter.nih.gov
Regulators of Photoreceptor Aerobic Glycolysis in Retinal Health and Disease	NIH	National Eye Institute	2023 to 2025	$1,294,491	September 1, 2023	June 30, 2027	RAJALA, RAJU VS	reporter.nih.gov
Admin Supplement: Village-Integrated Eye Worker Trial II (VIEW II)	NIH	National Eye Institute	2021 to 2023	$1,280,193	September 30, 2018	June 30, 2024	KEENAN, JEREMY DAVID	reporter.nih.gov
Metabolism of AMD iPSC-derived RPE	NIH	National Eye Institute	2022 to 2024	$1,268,628	September 30, 2022	August 31, 2025	CHAO, JENNIFER RAYMING	reporter.nih.gov
Rare Genetic Variation in Macular Degeneration	NIH	National Eye Institute	2021 to 2022	$1,264,456	September 30, 2018	June 30, 2024	SEDDON, JOHANNA M	reporter.nih.gov
Does age/stress-induced mitochondrial dysfunction induce variations in RPE phenotype in AMD?	NIH	National Eye Institute	2024 to 2025	$1,262,105	March 1, 2024	December 31, 2028	WANG, SHUSHENG	reporter.nih.gov
Intracellular RNA Nanoparticle Therapeutics to Treat Retinal Neovascularization	NIH	National Eye Institute	2023 to 2025	$1,250,122	September 1, 2023	May 31, 2027	FREEMAN, WILLIAM R.	reporter.nih.gov
Elucidating the Role of Very-long-chain Polyunsaturated Fatty Acids in Retinal Health and Disease	NIH	National Eye Institute	2023 to 2025	$1,246,125	July 1, 2023	June 30, 2027	BERNSTEIN, PAUL STEVEN	reporter.nih.gov
Identification of the specific risk allele responsible for oxidative stress in ARMS2/HTRA1-related AMD	NIH	National Eye Institute	2022 to 2024	$1,225,973	September 30, 2022	August 31, 2025	TSANG, STEPHEN H	reporter.nih.gov
Mechanistic study and therapeutic application of AIBP in AMD	NIH	National Eye Institute	2023 to 2025	$1,215,450	August 1, 2023	January 31, 2027	FU, YINGBIN	reporter.nih.gov
New statistical methods and software for modeling complex multivariate survival data with large-scale covariates	NIH	National Institute of General Medical Sciences	2022 to 2025	$1,213,700	June 1, 2022	May 31, 2027	DING, YING	reporter.nih.gov
Investigating the function and mechanism of interleukin 7 receptor-expressing pro-angiogenic macrophages during experimental choroidal neovascularization	NIH	National Eye Institute	2023 to 2025	$1,200,000	March 1, 2023	February 29, 2028	LAVINE, JEREMY A	reporter.nih.gov
Multimodal Molecular Imaging of Choroidal Neovascularization	NIH	National Eye Institute	2024 to 2025	$1,198,923	September 30, 2023	July 31, 2027	PAULUS, YANNIS MANTAS	reporter.nih.gov
Role of VEGFR2 trafficking in pathological angiogenesis in age related macular degeneration	NIH	National Eye Institute	2021 to 2023	$1,175,265	April 1, 2019	March 31, 2025	YAMADA, KAORI HORIGUCHI	reporter.nih.gov
Deciphering the mechanisms associated with high-risk AMD genotypes for ARMS2/HTRA1 andComplement Factor H	NIH	National Eye Institute	2022 to 2024	$1,174,621	September 30, 2022	August 31, 2025	FERRINGTON, DEBORAH ANN	reporter.nih.gov
Focused kV X-ray Modulated Conformal Radiotherapy for Small Targets	NIH	National Institute of Biomedical Imaging and Bioengineering	2021 to 2023	$1,174,067	September 20, 2021	January 31, 2025	HRISTOV, DIMITRE HRISTOV	reporter.nih.gov
AMPK/SIRT1/PGC-1α, a critical pathway in dry AMD	NIH	National Eye Institute	2021 to 2023	$1,169,908	April 1, 2019	March 31, 2025	GOLESTANEH, NADY	reporter.nih.gov
LIGHTSITE IIIB: Clinical Evaluation of Photobiomodulation (PBM) in dry AMD Patients	NIH	National Eye Institute	2023	$1,169,339	September 1, 2015	August 31, 2024	TEDFORD, CLARK E	reporter.nih.gov
Long-acting formulations of griseofulvin for ocular neovascularization therapy	NIH	National Eye Institute	2024 to 2025	$1,163,477	July 1, 2023	March 31, 2027	YEO, YOON	reporter.nih.gov
Comprehensive imaging and quantification of blood flow for investigating ocular diseases without additional contrast agent	NIH	National Eye Institute	2021 to 2022	$1,160,837	September 1, 2019	February 28, 2025	MUJAT, MIRCEA	reporter.nih.gov
VEGF Antagonism and Resistance to Neovascular AMD	NIH	National Eye Institute	2021 to 2023	$1,142,317	January 1, 2020	December 31, 2024	SORENSON, CHRISTINE M	reporter.nih.gov
Elucidating the developmental and molecular mechanism of chorioretinal anastomoses in a model of type 3 neovascular age-related macular degeneration	NIH	National Eye Institute	2021 to 2025	$1,142,220	September 30, 2021	August 31, 2026	KIM, TYSON NAM	reporter.nih.gov
Extracellular vesicle-based intraocular therapy combined with active targeting of ocular neovascularization	NIH	National Eye Institute	2024 to 2025	$1,135,383	February 1, 2024	January 31, 2029	LEE, SUN YOUNG	reporter.nih.gov
CELLULAR MECHANISMS OF PATHOLOGICAL RETINAL NEOVASCULARIZATION	NIH	National Eye Institute	2021 to 2023	$1,131,900	May 1, 2019	April 30, 2025	SINGH, NIKHLESH KUMAR	reporter.nih.gov
Non-canonical inflammasome in activation in RPE degeneration	NIH	National Eye Institute	2021 to 2022	$1,128,078	February 1, 2019	January 31, 2024	AMBATI, JAYAKRISHNA	reporter.nih.gov
Photoreceptor Disease in Inherited Retinal Degenerations	NIH	National Eye Institute	2024 to 2025	$1,101,893	February 1, 2024	January 31, 2029	CIDECIYAN, ARTUR V	reporter.nih.gov
Progression of Early Atrophic Lesions in Age-related Macular degeneration	NIH	National Eye Institute	2023 to 2025	$1,097,250	July 1, 2023	June 30, 2028	SCHMITZ-VALCKENBERG, STEFFEN	reporter.nih.gov
Aberrant RPE mTORC1 signaling in dysregulation of choroid homeostasis	NIH	National Eye Institute	2022 to 2025	$1,090,446	August 1, 2016	December 31, 2025	CHEN, YAN	reporter.nih.gov
Cell-based therapies for retinal degeneration	NIH	National Eye Institute	2024 to 2025	$1,084,596	June 1, 2024	May 31, 2028	CANTO-SOLER, MARIA VALERIA	reporter.nih.gov
Triple threat therapeutics for inherited retinal degenerations	NIH	National Eye Institute	2024 to 2025	$1,074,293	February 1, 2024	January 31, 2029	LAKKARAJU, APARNA	reporter.nih.gov
Novel Mechanisms of Subretinal Fibrosis in Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2023	$1,068,436	May 1, 2020	April 30, 2025	KANNAN, RAM	reporter.nih.gov
Essential Role of Very Long Chain Fatty Acids in Retinal Function	NIH	National Eye Institute	2021 to 2023	$1,065,750	September 30, 2019	June 30, 2025	AGBAGA, MARTIN-PAUL	reporter.nih.gov
Membrane Protein Effectors of Pathogen Interactions With Host	NIH	National Institute of General Medical Sciences	2021 to 2022	$1,063,700	June 1, 2016	September 30, 2022	MARASSI, FRANCESCA M	reporter.nih.gov
In vivo Imaging of the Human Retina at the Molecular Level	NIH	National Eye Institute	2024 to 2025	$1,047,218	March 1, 2024	February 29, 2028	SADDA, SRINIVAS R	reporter.nih.gov
Retinal Pigmented Epithelium Epigenome Dysregulation With Aging and Modulation by Diet	NIH	National Eye Institute	2024 to 2025	$1,042,808	March 1, 2024	January 31, 2029	FREEMAN, WILLARD M	reporter.nih.gov
In vivo Ultrastructure of Chorioretinal Disease	NIH	National Eye Institute	2021 to 2023	$1,033,059	January 1, 2015	August 31, 2025	ZHANG, YUHUA LIANG	reporter.nih.gov
Role of Runx1 in Pathologic Ocular Angiogenesis	NIH	National Eye Institute	2021 to 2022	$1,030,239	August 5, 2018	May 31, 2024	KIM, LEO A	reporter.nih.gov
Stargardt disease with low lipofuscin	NIH	National Eye Institute	2021 to 2022	$1,017,038	March 1, 2019	December 31, 2023	ALLIKMETS, RANDO L	reporter.nih.gov
Neuro-Optical Diagnostic System for Macular Degeneration	NIH	National Institute on Aging	2021 to 2022	$1,014,339	September 15, 2017	April 30, 2023	VERSEK, CRAIG	reporter.nih.gov
Regulators of retinal metabolism in healthy and degenerating retinas	NIH	National Eye Institute	2021 to 2022	$1,011,169	September 1, 2020	November 30, 2022	ASH, JOHN D	reporter.nih.gov
Photoreceptor Regeneration in a Murine Model of Leber Congenital Amaurosis	NIH	National Eye Institute	2021 to 2024	$1,007,900	August 1, 2020	July 31, 2025	UYHAZI, KATHERINE E.	reporter.nih.gov
Retinal Disease Promoted by Iron-Induced Bisretinoid Oxidation	NIH	National Eye Institute	2021 to 2022	$998,635	April 1, 2018	January 31, 2024	SPARROW, JANET RUTHE	reporter.nih.gov
Oculomotor Demands for Target Stabilization without Central Vision	NIH	National Eye Institute	2024 to 2025	$994,824	June 1, 2024	March 31, 2029	SHANIDZE, NATELA M.	reporter.nih.gov
Homocysteine's role in Age-Related Macular Degeneration	NIH	National Eye Institute	2021 to 2023	$976,244	August 1, 2021	January 31, 2025	TAWFIK, AMANY M	reporter.nih.gov
Prevention of macular pathophysiology associated with F3 misfolding	NIH	National Eye Institute	2021 to 2022	$968,905	February 1, 2018	August 31, 2023	HULLEMAN, JOHN DOUGLAS	reporter.nih.gov
A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)	NIH	National Eye Institute	2021 to 2023	$967,524	March 3, 2020	February 28, 2025	GAO, LIANG	reporter.nih.gov
Lipid Trafficking and Metabolism in the Retinal Pigment Epithelium	NIH	National Eye Institute	2022 to 2025	$960,368	March 1, 2022	May 31, 2027	MILLER, JASON MATTHEW-LEWIS	reporter.nih.gov
Nutritional Metabolomics in Age-Related Macular Degeneration and Retinal Integrity	NIH	National Eye Institute	2025	$929,348	August 1, 2025	March 31, 2029	MILLEN, AMY ELIZABETH	reporter.nih.gov
Understanding ABCA4 Variants of Unknown Significance Through Computational and Functional Approaches	NIH	National Eye Institute	2024 to 2025	$920,394	June 1, 2024	March 31, 2029	BISWAS-FISS, ESTHER ELISSA	reporter.nih.gov
The Use of Photobiomodulation (PBM) in the Treatment for Diabetic Macular Edema	NIH	National Eye Institute	2021 to 2022	$914,422	September 1, 2022	August 31, 2023	TEDFORD, CLARK E	reporter.nih.gov
Regulators of retinal metabolism in healthy and degenerating retinas	NIH	National Eye Institute	2023 to 2024	$907,882	September 1, 2020	June 30, 2025	ASH, JOHN D	reporter.nih.gov
Development of Two Novel AMD Models for Evaluation of RPE Protection by the Novel Antioxidant D-DHA	NIH	National Eye Institute	2024 to 2025	$886,684	September 1, 2024	March 31, 2028	DUNAIEF, JOSHUA L	reporter.nih.gov
Adaptive Optics Fluorescence Lifetime Ophthalmoscopy (AOFLIO) in healthy people and with disease	NIH	National Eye Institute	2021 to 2022	$836,229	September 1, 2021	December 31, 2023	HUNTER, JENNIFER J	reporter.nih.gov
Sustained Ocular Drug Delivery System for Anti-VEGF Agents	NIH	National Eye Institute	2022 to 2023	$818,678	May 1, 2019	February 28, 2026	KANG-MIELER, JENNIFER J	reporter.nih.gov
Topical delivery of HIF-1 inhibitors for retinal and choroidal vascular diseases	NIH	National Eye Institute	2024 to 2025	$807,886	July 1, 2024	June 30, 2028	ENSIGN, LAURA	reporter.nih.gov
Endothelial Transmigration in Neovascular Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2022	$807,137	April 1, 2007	March 31, 2023	HARTNETT, MARY ELIZABETH RUTH	reporter.nih.gov
Targeting SDF-1 for effective wet AMD treatment	NIH	National Eye Institute	2021	$805,217	August 1, 2020	July 31, 2024	GONG, QIANG	reporter.nih.gov
Quantitative Fundus Autofluorescence in Retinal Disorders	NIH	National Eye Institute	2021 to 2022	$785,700	June 1, 2014	December 31, 2023	SPARROW, JANET RUTHE	reporter.nih.gov
Role of Matrix Stiffness and Genetic Risk Factors in AMD-Associated Epithelial-to-Mesenchymal Transition	NIH	National Eye Institute	2024 to 2025	$780,170	September 1, 2024	March 31, 2029	WORTHINGTON, KRISTAN SORENSON	reporter.nih.gov
Targeting TGFB signaling to treat ocular neovascular disease	NIH	National Eye Institute	2023 to 2025	$771,759	March 1, 2003	April 30, 2027	ZARKADA, GEORGIA	reporter.nih.gov
Ocular MCMV latency and AMD-like pathology	NIH	National Eye Institute	2024 to 2025	$770,000	June 1, 2024	March 31, 2028	ZHANG, MING	reporter.nih.gov
Ferrochelatase as a mediator of ocular angiogenesis	NIH	National Eye Institute	2024 to 2025	$769,502	March 1, 2016	March 31, 2028	CORSON, TIMOTHY W	reporter.nih.gov
CRISPR-Cas9 based treatment of dominant retinal degeneration	NIH	National Eye Institute	2021 to 2022	$753,202	April 1, 2016	March 31, 2024	STONE, EDWIN M	reporter.nih.gov
The role of beta2-adrenergic receptor and interleukin-6 signaling in macrophage-driven choroidal neovascularization	NIH	National Eye Institute	2021 to 2024	$751,482	February 1, 2020	January 31, 2025	LAVINE, JEREMY A	reporter.nih.gov
A new class of wet AMD therapeutics	NIH	National Eye Institute	2024 to 2025	$739,831	September 30, 2023	June 30, 2027	PEARSALL, ELIZABETH	reporter.nih.gov
Sustained Treatment of wet AMD	NIH	National Eye Institute	2024 to 2025	$733,046	June 1, 2024	May 31, 2028	TUCKER, BUDD A	reporter.nih.gov
Mechanistically linking AMD, glycemic index and protein homeostasis	NIH	National Eye Institute	2021 to 2022	$732,353	September 30, 2018	June 30, 2024	TAYLOR, ALLEN	reporter.nih.gov
Mitochondrial retrograde signaling in RPE heterogeneity	NIH	National Eye Institute	2022 to 2024	$731,554	September 30, 2018	June 30, 2025	DATTA, SAYANTAN	reporter.nih.gov
Vascular Gene Delivery and Early Disease Biomarkers in Diabetic Retinopathy	NIH	National Eye Institute	2021 to 2022	$721,182	September 30, 2018	August 31, 2024	LIPINSKI, DANIEL MARK	reporter.nih.gov
Transport Processes in Photoreceptors	NIH	National Eye Institute	2021 to 2022	$718,078	September 6, 2004	June 30, 2024	KOUTALOS, YIANNIS	reporter.nih.gov
Investigating Membrane Trafficking Deficits in Choroideremia	NIH	National Eye Institute	2021 to 2023	$713,183	September 1, 2021	August 31, 2024	FAHIM, ABIGAIL	reporter.nih.gov
The Role of Histone Deacetylases in Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2022	$703,127	April 1, 2018	September 30, 2023	KLEINMAN, MARK E	reporter.nih.gov
Improving Accessibility of Vision Research and Therapy using an Open-Source, Extended-Reality Platform	NIH	National Eye Institute	2025	$687,692	September 1, 2025	April 30, 2030	SEITZ, AARON R	reporter.nih.gov
Gene therapy targeting CFH and lipoprotein dynamics in AMD	NIH	National Eye Institute	2025	$675,193	September 1, 2025	June 30, 2028	BOWES RICKMAN, CATHERINE	reporter.nih.gov
Visible-to-near-infrared spanning Optical Coherence Tomography for retinal imaging at the half-micron scale	NIH	National Eye Institute	2025	$673,747	June 1, 2025	May 31, 2030	SRINIVASAN, VIVEK JAY	reporter.nih.gov
Multimodal Molecular Imaging of Choroidal Neovascularization	NIH	National Eye Institute	2023	$671,124	September 30, 2023	July 31, 2024	PAULUS, YANNIS MANTAS	reporter.nih.gov
Sustained Ocular Drug Delivery System for Anti-VEGF Agents	NIH	National Eye Institute	2021 to 2022	$661,595	May 1, 2019	May 31, 2022	KANG-MIELER, JENNIFER J	reporter.nih.gov
Investigating the role of PLA2G2A/sPLA2-IIA in macular degeneration	NIH	National Eye Institute	2025	$658,889	July 1, 2025	April 30, 2029	SINGH, RUCHIRA	reporter.nih.gov
Bruch's Membrane-On-A-Chip to Study Drusen Formation in AMD	NIH	National Eye Institute	2025	$638,625	August 1, 2025	July 31, 2028	TOOMEY, CHRISTOPHER B	reporter.nih.gov
Editing AMD Risk Alleles in Human Cells	NIH	National Eye Institute	2025	$620,149	April 1, 2025	March 31, 2030	MULLINS, ROBERT FOSTER	reporter.nih.gov
Measures of Human Receptor and Post Receptor Activity	NIH	National Eye Institute	2021	$617,455	May 1, 1991	May 31, 2023	HOOD, DONALD C.	reporter.nih.gov
The preferred retinal locus in central vision loss	NIH	National Eye Institute	2025	$606,092	January 1, 2025	December 31, 2028	CHUNG, SUSANA T	reporter.nih.gov
Leica Stellaris 8 Confocal Microscope System	NIH	Office of the Director, National Institutes of Health	2022	$599,252	August 15, 2022	August 14, 2023	DALLAS, SARAH L	reporter.nih.gov
Mitochondrial defects in the retinal pigment epithelium and the CFH risk allele for age-related macular degeneration	NIH	National Eye Institute	2021	$567,508	April 1, 2018	March 31, 2022	FERRINGTON, DEBORAH ANN	reporter.nih.gov
Mechanisms of proinflammatory glial activation in retinal degeneration	NIH	National Eye Institute	2024 to 2025	$561,408	January 1, 2024	January 31, 2028	DISTASIO, MARCELLO MICHAEL	reporter.nih.gov
Genetics of central serous chorioretinopathy and choroidal thickening	NIH	National Eye Institute	2024 to 2025	$553,906	May 1, 2024	November 30, 2028	ROSSIN, ELIZABETH JEFFRIES	reporter.nih.gov
Impact of Sex on Mitochondrial and Epigenetic Mechanisms in Age-Related Macular Degeneration	NIH	National Institute on Aging	2025	$550,712	June 1, 2025	March 31, 2029	DEANGELIS, MARGARET M	reporter.nih.gov
Oxidative stress and innate immunity impair the visual cycle	NIH	National Eye Institute	2021	$537,024	March 1, 2017	February 28, 2022	HANDA, JAMES T	reporter.nih.gov
Long-acting formulations of griseofulvin for ocular neovascularization therapy	NIH	National Eye Institute	2023	$523,302	July 1, 2023	March 31, 2024	CORSON, TIMOTHY W	reporter.nih.gov
Histone Expression in the Aging RPE	NIH	National Eye Institute	2025	$521,572	January 1, 2025	December 31, 2029	KLEINMAN, MARK E	reporter.nih.gov
Mitochondrial Dynamics in RPE Homeostasis and Disease	NIH	National Eye Institute	2021	$518,575	March 1, 2018	August 31, 2022	PLAFKER, SCOTT M	reporter.nih.gov
cGAS signaling in oxidative retinal damage	NIH	National Eye Institute	2025	$513,371	April 1, 2025	March 31, 2030	KERUR, NAGARAJ	reporter.nih.gov
Role of Bruch Membrane Heparan Sulfate in Drusenogenesis in Age-Related Macular Degeneration	NIH	National Eye Institute	2024 to 2025	$509,578	July 1, 2024	June 30, 2029	TOOMEY, CHRISTOPHER B	reporter.nih.gov
Feasibility Studies for the Future Mediterranean Glucose Lowering Dietfor Vision Extension in AMD (M-GLOVE-AMD)	NIH	National Eye Institute	2024 to 2025	$504,037	September 1, 2024	August 31, 2027	HARTNETT, MARY ELIZABETH RUTH	reporter.nih.gov
Proteomics of human vitreous to investigate mechanisms underlying the variability in anti-VEGF treatment response in neovascular AMD patients	NIH	National Eye Institute	2022 to 2023	$481,250	September 1, 2022	August 31, 2024	BRANTLEY, MILAM A	reporter.nih.gov
Therapeutic inhibition of Fas-mediated retinal cell death and inflammation in dry AMD	NIH	National Eye Institute	2021 to 2022	$480,671	August 1, 2020	July 31, 2023	KOCAB, ANDREW JOSEPH	reporter.nih.gov
Development and Validation of Photothermal Optical Coherence Tomography for Retinal Imaging	NIH	National Eye Institute	2022 to 2023	$480,135	February 1, 2022	January 31, 2025	SKALA, MELISSA CAROLINE	reporter.nih.gov
Gene Regulation Underlying Photoreceptor Neurodegeneration	NIH	National Eye Institute	2025	$477,109	May 1, 2025	April 30, 2030	WERT, KATHERINE JEAN	reporter.nih.gov
Novel signaling pathways regulated by the liver x receptor in age-related macular degeneration	NIH	National Eye Institute	2021	$470,657	March 1, 2018	December 31, 2022	MALEK, GOLDIS	reporter.nih.gov
Enabling technology for image-guided robot-assisted sub-retinal injections	NIH	National Institute of Biomedical Imaging and Bioengineering	2021	$468,446	September 20, 2019	June 30, 2023	IORDACHITA, IULIAN IOAN	reporter.nih.gov
Modulation of Lipid Bisretinoids Clearance with Beta-Cyclodextrins	NIH	National Eye Institute	2021	$466,458	March 1, 2017	February 28, 2023	NOCIARI, MARCELO M	reporter.nih.gov
Pre-diagnosis Biomarker Discovery for Age-Related Macular Degeneration	NIH	National Eye Institute	2024 to 2025	$464,750	January 1, 2024	December 31, 2026	BLENKINSOP, TIMOTHY A.	reporter.nih.gov
Defining oxidative stress induced changes in RPE that control RPE and photoreceptor degeneration	NIH	National Eye Institute	2021	$464,735	August 1, 2016	May 31, 2023	BISWAL, MANAS R	reporter.nih.gov
Promoting RPE repair through modulation of Hippo signaling	NIH	National Eye Institute	2021 to 2022	$462,072	May 1, 2021	April 30, 2024	FUHRMANN, SABINE	reporter.nih.gov
Unifying Mechanism of Oxidative Stress and Inflammation in AMD	NIH	National Eye Institute	2024 to 2025	$460,350	January 1, 2024	December 31, 2026	DENNIS, MICHAEL D	reporter.nih.gov
A Novel Mouse Model for Spontaneous and Age-Related Choroidal Neovascularization	NIH	National Eye Institute	2024 to 2025	$457,875	August 1, 2024	July 31, 2026	FONG, GUO-HUA	reporter.nih.gov
Theranostic Nanovesicles for Ocular Angiogenesis Therapy	NIH	National Eye Institute	2022 to 2023	$450,313	February 1, 2022	January 31, 2024	FU, YINGLI	reporter.nih.gov
Identifying mechanisms that detect and eliminate aneuploid cells	NIH	National Eye Institute	2021 to 2022	$450,261	January 1, 2021	December 31, 2023	BAKER, NICHOLAS E	reporter.nih.gov
Ferrochelatase as a mediator of ocular angiogenesis	NIH	National Eye Institute	2023	$447,616	March 1, 2016	March 31, 2024	CORSON, TIMOTHY W	reporter.nih.gov
Structure-Function Relationships in Stargardt Disease.	NIH	National Eye Institute	2021 to 2022	$444,172	September 30, 2021	July 31, 2024	KONG, XIANGRONG	reporter.nih.gov
Sex-dependent aging mechanisms of retina and visual cortex	NIH	National Institute on Aging	2024 to 2025	$440,941	September 15, 2024	June 30, 2027	GOLESTANEH, NADY	reporter.nih.gov
Developing a novel disease-targeted anti-angiogenic therapy for CNV	NIH	National Eye Institute	2023	$440,000	September 30, 2023	August 31, 2025	LI, WEI	reporter.nih.gov
Learning-based 3D modeling of AMD to assess disease progression and response to treatment	NIH	National Eye Institute	2023	$433,841	September 30, 2023	August 31, 2025	HADZIAHMETOVIC, MAJDA	reporter.nih.gov
AMD Mitochondria Modulate Expression of microRNA 135b-5p and 148a-3p in RPE Cybrids: Implications for Age-related Macular Degeneration	NIH	National Eye Institute	2022 to 2023	$431,750	April 1, 2022	March 31, 2024	KEFALOV, VLADIMIR JIVKOV	reporter.nih.gov
A mouse model and iPS cells to study hyperactive ABCA1 in the eye in age-related macular degeneration	NIH	National Eye Institute	2021 to 2022	$429,931	April 1, 2021	March 31, 2025	LYSSENKO, NICHOLAS	reporter.nih.gov
Bcl-2, Subretinal Scar Formation and Neovascular AMD	NIH	National Eye Institute	2023	$427,625	September 30, 2023	August 31, 2025	SORENSON, CHRISTINE M	reporter.nih.gov
Discovery of Cell-based Chemical Probes Targeting Aberrant Angiogenesis in the Eye	NIH	National Eye Institute	2022 to 2023	$426,299	May 1, 2022	April 30, 2025	ROY, PARTHA	reporter.nih.gov
Regeneration of human RPE cells from autologous urine-derived iPS cells	NIH	National Eye Institute	2024 to 2025	$426,250	February 1, 2024	January 31, 2027	ZHANG, YUANYUAN NO	reporter.nih.gov
Regulation of inflammation and lipid homeostasis by the aryl hydrocarbon receptor in age-related macular degeneration	NIH	National Eye Institute	2021	$424,100	May 1, 2018	April 30, 2023	MALEK, GOLDIS	reporter.nih.gov
Precisely removing microvessels by photo-mediated ultrasound therapy	NIH	National Eye Institute	2021	$423,990	September 1, 2018	July 31, 2024	YANG, XINMAI	reporter.nih.gov
A Phase 2 Study of the Value of Pre-symptomatic Genetic Risk Assessment for Age-Related Macular Degeneration	NIH	National Eye Institute	2022 to 2023	$422,646	May 1, 2022	April 30, 2025	BERNSTEIN, PAUL STEVEN	reporter.nih.gov
AMD-Patient-Derived hiPSC-RPE: Gateway for Assessing Novel and Emerging Modulators of Autophagy	NIH	National Eye Institute	2021 to 2022	$419,081	September 30, 2021	July 1, 2024	AHMED, ZUBAIR M.	reporter.nih.gov
Exosome based intraocular therapy combined with active targeting of ocular neovascularization	NIH	National Eye Institute	2022	$417,431	September 30, 2022	September 29, 2024	LEE, SUN YOUNG	reporter.nih.gov
New methods to quantify and train eye movement strategies in macular degeneration	NIH	National Eye Institute	2022 to 2023	$413,729	February 1, 2022	June 30, 2025	MANIGLIA, MARCELLO	reporter.nih.gov
Characterization of human RPE subpopulations at the single cell level	NIH	National Eye Institute	2021	$412,250	September 1, 2018	May 31, 2023	STERN, JEFFREY H	reporter.nih.gov
Therapeutic genome editing to treat Best disease	NIH	National Eye Institute	2021	$412,056	September 30, 2017	June 30, 2022	CONKLIN, BRUCE R	reporter.nih.gov
Adenosine receptor 2A in subretinal fibrosis	NIH	National Eye Institute	2025	$402,276	May 1, 2022	March 31, 2027	HUO, YUQING	reporter.nih.gov
Targeting peptide Lv and its downstream signaling against ocular neovascularization	NIH	National Eye Institute	2021 to 2022	$401,344	June 1, 2021	May 31, 2024	KO, GLADYS Y	reporter.nih.gov
Characterizing the prevalence and nature of facial recognition deficits in non-proliferative diabetic retinopathy	NIH	National Eye Institute	2023 to 2024	$398,311	June 1, 2023	May 31, 2026	WENGER, MICHAEL J	reporter.nih.gov
A new class of wet AMD therapeutics	NIH	National Eye Institute	2022	$391,250	September 30, 2022	April 30, 2024	PEARSALL, ELIZABETH	reporter.nih.gov
A new class of wet AMD therapeutics	NIH	National Eye Institute	2023	$391,250	September 30, 2023	June 30, 2024	PEARSALL, ELIZABETH	reporter.nih.gov
RPE, aging and age-related macular degeneration: the role of oxidative stress	NIH	National Eye Institute	2021	$390,425	September 1, 2017	May 31, 2022	BONILHA, VERA L	reporter.nih.gov
Evaluation of New Anti-inflammatory Treatments for Age-Related Macular Degeneration	NIH	National Eye Institute	2023 to 2024	$388,655	September 30, 2023	August 31, 2025	SWINDLE-REILLY, KATELYN E	reporter.nih.gov
Novel therapies for macular degeneration, transthyretin amyloidosis and their common age-related comorbidities	NIH	National Eye Institute	2022	$383,990	February 1, 2018	September 29, 2024	PETRUKHIN, KONSTANTIN	reporter.nih.gov
Domain-adaptive federated learning to develop machine learning models for predicting incident and progression of geographic atrophy	NIH	National Eye Institute	2024	$379,363	July 1, 2024	June 30, 2026	ALAM, MINHAJ NUR	reporter.nih.gov
Protective Effects of Humanin on AMD Mitochondria	NIH	National Eye Institute	2021	$377,208	March 1, 2019	February 28, 2022	KENNEY, MARIA C	reporter.nih.gov
Novel pro-drug pharmacotherapy to prevent neuronal and cell degeneration in AMD	NIH	National Eye Institute	2021	$375,875	September 30, 2019	July 31, 2023	KOULEN, PETER	reporter.nih.gov
Elucidation of the Regulation of Angiogenesis by Melanocytes in Age Related Macular Degeneration	NIH	National Eye Institute	2021	$373,207	June 1, 2017	May 31, 2022	ADINI, IRIT	reporter.nih.gov
Regulation of Ocular Angiogenesis by microRNAs	NIH	National Eye Institute	2021	$368,600	September 1, 2011	June 30, 2023	WANG, SHUSHENG	reporter.nih.gov
Adaptive Optics Fluorescence Lifetime Ophthalmoscopy (AOFLIO) in healthy people and with disease	NIH	National Eye Institute	2024 to 2025	$361,595	September 1, 2021	June 30, 2027	HUNTER, JENNIFER J	reporter.nih.gov
A critical role for intracellular VEGF receptor translocation in ocular angiogenesis	NIH	National Eye Institute	2021	$360,112	May 1, 2018	April 30, 2022	BOULTON, MICHAEL EDWIN	reporter.nih.gov
Transgenerational Impact of Childhood Maltreatment on Structural/Functional Properties of Visual Cortex	NIH	Eunice Kennedy Shriver National Institute of Child Health & Human Development	2022 to 2025	$359,412	July 31, 2019	July 31, 2026	FLEMING, LELAND	reporter.nih.gov
NEUROVASCULAR CROSS-TALK, FUNCTIONS AND SOURCES OF SOLUBLE VEGF RECEPTORS IN OCULAR VASCULAR DEMARCATION	NIH	National Eye Institute	2021	$357,688	May 1, 2008	March 31, 2023	AMBATI, BALAMURALI K	reporter.nih.gov
The control of retinal vascular development by Norrin and Frizzled4	NIH	National Eye Institute	2021	$357,384	January 1, 2008	June 30, 2023	NATHANS, JEREMY	reporter.nih.gov
Müller glia in disease and stress	NIH	National Eye Institute	2021	$351,625	September 1, 2017	May 31, 2023	LE, YUN ZHENG	reporter.nih.gov
Novel Polymer-antibody Conjugates as Long-acting Therapeutics for Ocular Diseases	NIH	National Eye Institute	2023	$350,075	September 1, 2023	June 30, 2025	PENG, FEI	reporter.nih.gov
Novel injectable implants for long-term local controlled release of therapeutic monoclonal antibodies	NIH	National Institute of General Medical Sciences	2025	$350,027	August 1, 2025	July 31, 2027	KRISHNAN, VISHALAKSHI	reporter.nih.gov
RPE Trophic Activity for Retinal Protection	NIH	National Eye Institute	2021	$338,904	April 1, 2017	February 28, 2023	MCKAY, BRIAN S	reporter.nih.gov
Elucidating the Molecular Underpinnings of Endogenous RPE Regeneration	NIH	National Eye Institute	2021 to 2022	$335,883	June 1, 2019	August 31, 2022	GROSS, JEFFREY	reporter.nih.gov
Mechanisms of retinal angiogenesis	NIH	National Eye Institute	2021	$331,740	June 1, 2006	March 31, 2023	RAO, GADIPARTHI N	reporter.nih.gov
Vector mediated anti-vascular and anti-inflammatory therapy for AMD	NIH	National Eye Institute	2025	$310,952	August 1, 2025	July 31, 2027	GILGER, BRIAN C	reporter.nih.gov
Responses of the Macula to Toxicant Injury: The Role(s) of PGC1α Isoforms in Photoreceptor Neuroprotection	NIH	National Eye Institute	2021 to 2022	$307,650	March 1, 2019	February 29, 2024	MOWAT, FREYA	reporter.nih.gov
Ultrastructural Analysis of a Form of Macular Degeneration - Macular Telangiectasia	NIH	National Eye Institute	2021 to 2022	$307,181	May 1, 2020	April 30, 2023	DOWLING, JOHN E	reporter.nih.gov
Drug Screening Platform in the Light-Responsive Human Eye	NIH	National Eye Institute	2025	$306,118	April 1, 2025	March 31, 2027	ALLEN, JORDAN	reporter.nih.gov
Topical Ophthalmic Treatment for Neovascular Age-related Macular Degeneration (nAMD)	NIH	National Eye Institute	2025	$305,321	September 30, 2025	September 29, 2026	SERIZAWA, HIROAKI	reporter.nih.gov
Developing Scg3 Raptamers as a novel targeted therapy for wet AMD	NIH	National Eye Institute	2025	$300,016	September 1, 2025	August 31, 2026	VARADHACHARY, ATUL	reporter.nih.gov
Line Scan Swept Source OCT (LS-SS-OCT)	NIH	National Eye Institute	2025	$300,001	July 1, 2025	June 30, 2026	ATIA, WALID	reporter.nih.gov
Development of a novel therapy for the treatment of age-related macular degeneration	NIH	National Eye Institute	2022	$299,703	September 1, 2022	August 31, 2023	MOODY, KELSEY	reporter.nih.gov
Evaluating the efficacy of Butyric acid pro-drug nanoparticle in retinal neuroprotection	NIH	National Eye Institute	2023	$296,790	April 1, 2023	March 31, 2025	BISWAL, MANAS R	reporter.nih.gov
Development of the First-ever Safe and Effective Anterior Chamber Paracentesis Instrument to Treat and Diagnose Ocular Diseases	NIH	National Eye Institute	2021	$293,556	September 1, 2021	August 31, 2022	FARAH, SAMER	reporter.nih.gov
A Novel Small Molecule for The Prevention and Treatment of Age-Related Macular Degeneration	NIH	National Eye Institute	2021	$277,289	September 1, 2021	August 31, 2023	SHIN, HENRY YOUNGHWA	reporter.nih.gov
Cholesterol Removal as a Treatment for Dry Age-Related Macular Degeneration	NIH	National Eye Institute	2024	$276,758	April 1, 2024	March 31, 2025	MEHTA, NEHAL N	reporter.nih.gov
Dual Targeting Mitochondria and GPCR in Retinal Protection	NIH	National Eye Institute	2022	$255,710	September 1, 2022	August 31, 2023	CHANG, QING	reporter.nih.gov
Reconstruction of a human blood-retina barrier and perfused vascular system to investigate the role of APOE variants in age-related macular degeneration	NIH	National Eye Institute	2025	$253,500	February 1, 2025	January 31, 2027	MESENTIER LOURO, LOUISE ALESSANDRA	reporter.nih.gov
The Role of RPE-derived Exosomes in Deposit Formation and ECM Modulation	NIH	National Eye Institute	2022	$253,200	September 1, 2021	August 31, 2024	KLINGEBORN, MIKAEL	reporter.nih.gov
RPE PFKFB3 in subretinal fibrosis	NIH	National Eye Institute	2025	$249,000	September 1, 2023	June 30, 2028	YANG, QIUHUA	reporter.nih.gov
Developing multi-specific aptamers for safe, potent, and long-lasting treatment of geographic atrophy	NIH	National Eye Institute	2022	$247,641	July 1, 2022	June 30, 2024	WANG, JINPENG	reporter.nih.gov
Genetic Variation in AMD Progression and Treatment Response	NIH	National Eye Institute	2025	$244,379	September 15, 2025	March 31, 2030	AU, ADRIAN C	reporter.nih.gov
Nuclear encoded Humanin Isoforms and Mitochondria in Age-related Macular Degeneration	NIH	National Eye Institute	2025	$240,713	February 1, 2025	January 31, 2027	ZHANG, SARAH X	reporter.nih.gov
Integrative analysis of bulk and single-cell RNA-seq data from human retina for age-related macular degeneration	NIH	National Eye Institute	2021	$239,653	September 1, 2020	August 31, 2023	LI, MINGYAO	reporter.nih.gov
Functional impact of fixational eye movements in central vision loss	NIH	National Eye Institute	2021	$233,527	September 1, 2020	June 30, 2024	CHUNG, SUSANA T	reporter.nih.gov
RPE PFKFB3 in subretinal fibrosis	NIH	National Eye Institute	2023 to 2024	$230,942	September 1, 2023	August 31, 2025	YANG, QIUHUA	reporter.nih.gov
Oral metformin for non-neovascular age-related macular degeneration	NIH	National Eye Institute	2021	$229,145	August 1, 2020	July 31, 2022	STEWART, JAY MICHAEL	reporter.nih.gov
Partial epigenetic reprogramming of retinal pigment cells in age-related degeneration, dysfunction, and injury	NIH	National Eye Institute	2023 to 2024	$228,078	July 1, 2023	June 30, 2025	HU, ZHENGPING	reporter.nih.gov
Real-time In Vivo Visualization of the Molecular Processes in Choroidal Neovascularization	NIH	National Eye Institute	2021	$224,397	September 1, 2018	August 31, 2022	PAULUS, YANNIS MANTAS	reporter.nih.gov
hiPSC-derived tissue mimetics of the retina blood barrier	NIH	National Eye Institute	2021	$224,070	February 1, 2020	January 31, 2023	BENOIT, DANIELLE S.	reporter.nih.gov
Comparative Analysis of Retinal Glial Support Programs	NIH	National Eye Institute	2021	$222,559	April 1, 2020	March 31, 2023	COOK, TIFFANY	reporter.nih.gov
Deep-learning-based prediction of AMD and its progression with GWAS and fundus image data	NIH	National Eye Institute	2021	$220,287	August 1, 2020	May 31, 2023	DING, YING	reporter.nih.gov
Formation of Retinyl-Opsins by Retinyl Formate as Molecular Shades Against Light-Induced Retinal Damage	NIH	National Eye Institute	2022 to 2025	$194,555	January 24, 2022	January 23, 2026	HONG, JOHN DONG-HOON	reporter.nih.gov
The Role of RPE-derived Exosomes in Deposit Formation and ECM Modulation	NIH	National Eye Institute	2021	$194,293	September 1, 2021	August 31, 2022	KLINGEBORN, MIKAEL	reporter.nih.gov
Artificial Intelligence for Assessment of Stargardt Macular Atrophy	NIH	National Eye Institute	2021	$190,362	January 1, 2020	December 31, 2023	HU, ZHIHONG	reporter.nih.gov
Novel function of beta-catenin in regulation of RPE basal membrane	NIH	National Eye Institute	2021	$189,150	September 1, 2020	August 31, 2022	LU, QINGXIAN	reporter.nih.gov
Role of choroidal macrophages in regulating lipid homeostasis and immunosuppression of the RPE/choroid	NIH	National Eye Institute	2021 to 2024	$179,912	September 1, 2021	August 31, 2025	FORTMANN, SETH D	reporter.nih.gov
Systematic Identification and Mechanistic Characterization of Novel Oxidative Protective Genes to Prevent RPE Degeneration	NIH	National Eye Institute	2025	$173,016	August 1, 2025	July 31, 2027	LU, YUANCHENG	reporter.nih.gov
Co-Delivery Dose-Controllable Implants for Advanced Chronic Eye Disease Treatment	NIH	National Center for Advancing Translational Sciences	2023 to 2024	$160,105	July 1, 2023	June 30, 2025	PARK, YOONJEE	reporter.nih.gov
An animal model for cytomegalovirus-induced pathology in the developing retina	NIH	National Institute of Allergy and Infectious Diseases	2022 to 2023	$156,000	February 1, 2022	January 31, 2025	SNYDER, CHRISTOPHER M	reporter.nih.gov
Epigenetic Modifiers to treat Photoreceptor Degenerations	NIH	National Eye Institute	2023	$149,664	July 1, 2023	June 30, 2025	TOMBRAN-TINK, JOYCE	reporter.nih.gov
THE PURPOSE OF THIS MODIFICATION IS TO CREATE ISOGENIC CELL CONTROL LINES FOR THE LINES CURRENTLY BEING CREATED.	NIH	Office of the Director, National Institutes of Health	2021	$149,500	September 25, 2018	March 24, 2022	NOGGLE, SCOTT	reporter.nih.gov
Recording gaze-corrected electroretinograms using eye-tracking	NIH	National Eye Institute	2021	$148,531	February 1, 2020	January 31, 2023	PANORGIAS, ATHANASIOS	reporter.nih.gov
IL-1Beta-Induced Retinal Iron Accumulation in Age-Related Macular Degeneration	NIH	National Eye Institute	2021 to 2023	$120,861	January 1, 2021	May 15, 2023	STERLING, JACOB KHAN	reporter.nih.gov
Homocysteine's role in Age-Related Macular Degeneration	NIH	National Eye Institute	2021	$120,059	February 1, 2019	July 31, 2021	TAWFIK, AMANY M	reporter.nih.gov
Altered RPE matrix in Sorsby Fundus Dystrophy leads to metabolic dysfunction	NIH	National Eye Institute	2021 to 2023	$118,363	September 10, 2021	September 9, 2024	GRENELL, ALLISON BROOKE	reporter.nih.gov
Investigating the role of active Rap1a binding IQGAP1 in choroidal neovascularization	NIH	National Eye Institute	2021 to 2023	$116,011	September 30, 2021	May 31, 2024	RAMSHEKAR, ANIKET	reporter.nih.gov
Retinal Degeneration Conference	NIH	National Eye Institute	2023 to 2025	$110,001	February 14, 2023	February 28, 2026	ASH, JOHN D	reporter.nih.gov
Structured quantification of inherited macular disease phenotypes as the basis for automated algorithms to determine causal genes	NIH	National Eye Institute	2025	$105,516	January 1, 2025	December 31, 2026	LEE, WINSTON	reporter.nih.gov
Characterizing the role of mitochondrial DNA mutations on retinal degeneration.	NIH	National Eye Institute	2024 to 2025	$98,512	February 1, 2024	January 31, 2027	STURGIS, JOHNATHON BRIAN	reporter.nih.gov
Role of ELOVL2 in age-related visual decline	NIH	National Eye Institute	2024 to 2025	$96,066	May 1, 2024	April 30, 2028	TOM, EMILY	reporter.nih.gov
Deciphering the role of mitochondrial/autophagy dysfunction in regulating inflammatory processes during AMD pathogenesis	NIH	National Eye Institute	2023	$92,707	September 1, 2023	July 1, 2024	GHOSH, SAYAN	reporter.nih.gov
Deciphering the role of mitochondrial/autophagy dysfunction in regulating inflammatory processes during AMD pathogenesis	NIH	National Eye Institute	2024	$92,707	September 1, 2023	August 31, 2025	GHOSH, SAYAN	reporter.nih.gov
Strategies to Control Alternative Pathway Activation in Age-Related Sensory Loss.	NIH	National Institute of Neurological Disorders and Stroke	2021 to 2022	$92,396	September 1, 2021	August 31, 2023	PARSONS, NATHANIEL BRYAN DAVID	reporter.nih.gov
RPE Exosomes in Age-related Macular Degeneration	NIH	National Eye Institute	2021 to 2024	$90,596	January 1, 2022	February 9, 2024	HERNANDEZ, BELINDA J	reporter.nih.gov
Dual CRISPR/Cas9 exon deleting approach for the treatment of USH2A-associated disorders	NIH	National Eye Institute	2024	$88,560	September 1, 2021	July 31, 2028	PARSONS, NATHANIEL BRYAN DAVID	reporter.nih.gov
The Membrane Attack Complex and the Choriocapillaris in Health and Age-Related Macular Degeneration	NIH	National Eye Institute	2021 to 2022	$77,663	July 21, 2020	May 12, 2023	VOIGT, ANDREW P	reporter.nih.gov
Hippo Signaling in Regeneration of the Retinal Pigment Epithelium	NIH	National Eye Institute	2021 to 2023	$69,333	April 1, 2021	May 31, 2023	RAMIREZ, SARA	reporter.nih.gov
Comparative Single Cell Profiling of Retinal Development	NIH	National Eye Institute	2021 to 2022	$68,454	May 3, 2021	June 30, 2022	WEIR, KURT L	reporter.nih.gov
Retinal Degeneration Conference	NIH	National Eye Institute	2021 to 2022	$55,001	June 21, 2012	November 30, 2022	ASH, JOHN D	reporter.nih.gov
CRISPR/Cas9-Mediated Correction of Abca4 Mutations in a Stargardt Mouse Model	NIH	National Eye Institute	2021	$51,036	January 15, 2019	January 14, 2022	SUH, SUSIE	reporter.nih.gov
Dysregulation of Wnt signaling in subretinal fibrosis in AMD	NIH	National Eye Institute	2021	$48,033	September 1, 2021	November 19, 2021	TAKAHASHI, YUSUKE	reporter.nih.gov
Characterizing Shared Features of Innate Immune Cells across Neurodegenerative Diseases using Single Cell Expression and Chromatin Accessibility Data	NIH	National Institute of Allergy and Infectious Diseases	2021 to 2022	$43,635	January 16, 2021	May 31, 2022	KUCHROO, MANIK	reporter.nih.gov
Investigating Mitochodrial Homeostasis as a Pathological Mechanism of Age Related Macular Degeneration	NIH	National Eye Institute	2021 to 2022	$42,554	March 1, 2021	May 2, 2022	FISHER, CODY R	reporter.nih.gov
7th Biennial Symposium on AMD	NIH	National Eye Institute	2025	$40,000	September 1, 2025	August 31, 2026	D'AMORE, PATRICIA ANN	reporter.nih.gov
Adaptive Neuroplasticity Following Central Visual Field Loss in Macular Degeneration	NIH	National Institute of Neurological Disorders and Stroke	2021	$15,500	August 1, 2021	January 31, 2022	FLEMING, LELAND	reporter.nih.gov

Organizations

Organization	Place	NIH awards	NIH amount	NSF amount
Jaeb Center for Health Research, Inc.	Tampa, FL	1	$43.2 million	$0
The Emmes Company, LLC	Rockville, MD	2	$32.6 million	$0
Columbia University Health Sciences	New York, NY	10	$18.1 million	$0
Johns Hopkins University	Baltimore, MD	16	$17.8 million	$0
University of Utah	Salt Lake City, UT	10	$13.4 million	$0
University of Pennsylvania	Philadelphia, PA	9	$11.5 million	$0
University of Iowa	Iowa City, IA	9	$9.6 million	$0
Doheny Eye Institute	Pasadena, CA	7	$9.4 million	$0
University of Alabama at Birmingham	Birmingham, AL	7	$9.1 million	$0
University of California, San Diego	La Jolla, CA	6	$9 million	$0
University of California at Davis	Davis, CA	4	$8.6 million	$0
Duke University	Durham, NC	9	$7.8 million	$0
University of Washington	Seattle, WA	4	$7.3 million	$0
University of Virginia	Charlottesville, VA	4	$7.1 million	$0
University of Pittsburgh at Pittsburgh	Pittsburgh, PA	9	$7 million	$0
University of California, San Francisco	San Francisco, CA	5	$6.6 million	$0
University of Rochester	Rochester, NY	5	$5.7 million	$0
Oregon Health & Science University	Portland, OR	2	$5.4 million	$0
Regenerative Research Foundation	Albany, NY	3	$5.2 million	$0
University of Oklahoma HLTH Sciences CTR	Oklahoma City, OK	6	$5.2 million	$0
Case Western Reserve University	Cleveland, OH	4	$5.2 million	$0
Stanford University	Stanford, CA	4	$5.2 million	$0
Medical University of South Carolina	Charleston, SC	5	$5.1 million	$0
Yale University	New Haven, CT	4	$4.6 million	$0
University of Wisconsin-Madison	Madison, WI	4	$4.4 million	$0
Augusta University	Augusta, GA	5	$4 million	$0
University of Maryland Baltimore	Baltimore, MD	3	$4 million	$0
Northwestern University at Chicago	Chicago, IL	3	$4 million	$0
Wake Forest University Health Sciences	Winston-Salem, NC	3	$3.9 million	$0
West Virginia University Research Corporation	Morgantown, WV	2	$3.9 million	$0
Massachusetts General Hospital	Boston, MA	3	$3.5 million	$0
Jackson Laboratory	Bar Harbor, ME	2	$3.4 million	$0
Baylor College of Medicine	Houston, TX	4	$3.4 million	$0
Univ of Massachusetts Med SCH Worcester	Worcester, MA	2	$3.3 million	$0
Medical College of Wisconsin	Milwaukee, WI	2	$3.2 million	$0
University of Southern California	Los Angeles, CA	3	$3.2 million	$0
Cleveland Clinic Lerner Com-Cwru	Cleveland, OH	4	$3.1 million	$0
Massachusetts Eye and Ear Infirmary	Boston, MA	3	$3 million	$0
Ihealthscreen, Inc.	Richmond Hill, NY	1	$2.9 million	$0
Nanoscope Technologies, LLC	Arlington, TX	2	$2.8 million	$0
Smith-Kettlewell Eye Research Institute	San Francisco, CA	2	$2.7 million	$0
University of Colorado Denver	Aurora, CO	2	$2.7 million	$0
Ohio State University	Columbus, OH	3	$2.6 million	$0
University of Michigan at Ann Arbor	Ann Arbor, MI	4	$2.6 million	$0
University of California-Irvine	Irvine, CA	5	$2.5 million	$0
New York University School of Medicine	New York, NY	2	$2.3 million	$0
Indiana University Indianapolis	Indianapolis, IN	3	$2.3 million	$0
Weill Medical Coll of Cornell Univ	New York, NY	2	$2.1 million	$0
University of South Florida	Tampa, FL	2	$2.1 million	$0
Lumithera, Inc.	Poulsbo, WA	2	$2.1 million	$0
University of Minnesota	Minneapolis, MN	3	$2.1 million	$0
Boston Children's Hospital	Boston, MA	1	$2 million	$0
Brigham and Women's Hospital	Boston, MA	1	$2 million	$0
Seattle Children's Hospital	Seattle, WA	1	$2 million	$0
LSU Health Sciences Center	New Orleans, LA	1	$2 million	$0
Florida International University	Miami, FL	1	$2 million	$0
Revopsis Therapeutics, Inc.	Springfield, IL	1	$1.9 million	$0
University of Tennessee Health Sci CTR	Memphis, TN	2	$1.9 million	$0
Regents of the University of Idaho	Moscow, ID	1	$1.8 million	$0
University of Missouri-Kansas City	Kansas City, MO	4	$1.8 million	$0
SUNY at Buffalo	Amherst, NY	3	$1.7 million	$0
Massachusetts Institute of Technology	Cambridge, MA	1	$1.7 million	$0
Abzyme Therapeutics, LLC	Pottstown, PA	1	$1.7 million	$0
Tulane University of Louisiana	New Orleans, LA	2	$1.6 million	$0
Georgetown University	Washington, DC	2	$1.6 million	$0
Oklahoma Medical Research Foundation	Oklahoma City, OK	2	$1.6 million	$0
Eclipse Life Sciences, Inc.	Research Triangle Park, NC	1	$1.5 million	$0
Ut Southwestern Medical Center	Dallas, TX	2	$1.4 million	$0
Brown University	Providence, RI	1	$1.4 million	$0
Aeon Imaging, LLC	Bloomington, IN	1	$1.4 million	$0
Wayne State University	Detroit, MI	2	$1.4 million	$0
Schepens Eye Research Institute	Boston, MA	3	$1.3 million	$0
East Tennessee State University	Johnson City, TN	2	$1.2 million	$0
University of California Los Angeles	Los Angeles, CA	2	$1.2 million	$0
University of Illinois at Chicago	Chicago, IL	1	$1.2 million	$0
Purdue University	West Lafayette, IN	1	$1.2 million	$0
Physical Sciences, INC	Andover, MA	1	$1.2 million	$0
University of Florida	Gainesville, FL	2	$1.1 million	$0
Sanford Burnham Prebys Medical Discovery Institute	La Jolla, CA	1	$1.1 million	$0
Aptitude Medical Systems, Inc.	Santa Barbara, CA	2	$1.1 million	$0
Neurofieldz, Inc.	Newton, MA	1	$1 million	$0
Oakland University	Rochester, MI	1	$976,244	$0
Vanderbilt University Medical Center	Nashville, TN	2	$943,322	$0
University of Delaware	Newark, DE	1	$920,394	$0
University of California-Berkeley	Berkeley, CA	2	$839,619	$0
Stevens Institute of Technology	Hoboken, NJ	1	$818,678	$0
University of Connecticut	Storrs, CT	1	$771,759	$0
University of Toronto	Toronto	1	$769,502	$0
Tufts University Boston	Boston, MA	1	$732,353	$0
Emory University	Atlanta, GA	1	$731,554	$0
Icahn School of Medicine at Mount Sinai	New York, NY	2	$718,250	$0
Northeastern University	Boston, MA	1	$687,692	$0
Illinois Institute of Technology	Chicago, IL	1	$661,595	$0
Columbia University	New York, NY	1	$617,455	$0
Onl Therapeutics, Inc.	Ann Arbor, MI	1	$480,671	$0
Morgridge Institute for Research, Inc.	Madison, WI	1	$480,135	$0
Pennsylvania State Univ Hershey Med CTR	Hershey, PA	1	$460,350	$0
University of Connecticut SCH of Med/dnt	Farmington, CT	1	$457,875	$0
Albert Einstein College of Medicine	Bronx, NY	1	$450,261	$0
Temple Univ of the Commonwealth	Philadelphia, PA	1	$429,931	$0

Funding by fiscal year

Fiscal year	NIH awards	NIH amount	NSF amount
2025	136	$75,220,663	$0
2024	158	$85,953,899	$0
2023	164	$82,267,125	$0
2022	166	$81,902,814	$0
2021	167	$85,312,747	$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunity	Number	Agency	Listing	Closes	Award ceiling	Why it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)	PA-24-254	NIH		July 12, 2027	Not listed	Notice number printed on 4 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)	PA-24-194	NIH		May 7, 2027	Not listed	Notice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)	PA-24-185	NIH		May 7, 2027	Not listed	Notice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)	PA-25-080	NIH		September 7, 2027	Not listed	Notice number printed on 1 award here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)	PAR-25-369	NIH	93.867	November 18, 2026	Not listed	Same assistance listing 93.867 as 300 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)	PAR-25-371	NIH	93.867	November 18, 2026	Not listed	Same assistance listing 93.867 as 300 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)	PA-23-317	NIH	93.867	November 24, 2026	Not listed	Same assistance listing 93.867 as 300 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)	PAR-24-296	NIH	93.867	December 3, 2026	Not listed	Same assistance listing 93.867 as 300 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)	RFA-OD-24-011	NIH	93.867	December 4, 2026	Not listed	Same assistance listing 93.867 as 300 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)	PAR-27-039	NIH	93.867	January 5, 2027	Not listed	Same assistance listing 93.867 as 300 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)	PAR-27-040	NIH	93.867	January 5, 2027	Not listed	Same assistance listing 93.867 as 300 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)	PAR-24-214	NIH	93.867	January 7, 2027	$375,000	Same assistance listing 93.867 as 300 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)	RFA-NS-25-023	NIH	93.867	January 15, 2027	$350,000	Same assistance listing 93.867 as 300 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)	PAR-24-268	NIH	93.867	January 27, 2027	$500,000	Same assistance listing 93.867 as 300 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)	RFA-NS-24-031	NIH	93.867	January 28, 2027	$750,000	Same assistance listing 93.867 as 300 awards here
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)	RFA-MH-26-170	NIH	93.867	February 8, 2027	Not listed	Same assistance listing 93.867 as 300 awards here
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)	RFA-DC-27-004	NIH	93.867	February 11, 2027	$700,000	Same assistance listing 93.867 as 300 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)	RFA-LM-28-001	NIH	93.867	February 11, 2027	$775,000	Same assistance listing 93.867 as 300 awards here
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)	PAR-27-081	NIH	93.867	March 5, 2027	Not listed	Same assistance listing 93.867 as 300 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)	PA-27-100	NIH	93.867	April 5, 2027	Not listed	Same assistance listing 93.867 as 300 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.