Data / Research funding / Lupus
Lupus: 398 NIH awards ($541.2M) to 122 organizations
398 NIH awards ($541.2M) in the NIH spending category Lupus, to 122 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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398 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Regulation of B cell Responses in SLE and Other Autoimmune Diseases | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $53,786,694 | May 1, 2014 | April 30, 2029 | SANZ, IGNACIO E. | reporter.nih.gov |
| Accelerating Medicines Partnership-Autoimmune and Immunologic Disease Tissue Research Core | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $19,601,747 | March 23, 2022 | December 31, 2026 | GUTHRIDGE, JOEL MARVIN | reporter.nih.gov |
| Center for Quantitative Biology: A focus on "omics", from organisms to single cells | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $17,122,562 | August 1, 2019 | June 30, 2029 | WHITFIELD, MICHAEL L | reporter.nih.gov |
| Anti-NMDA Receptor Antibodies in Adult Brain Dysfunction: Lessons from Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $14,990,990 | August 1, 2008 | June 30, 2030 | DIAMOND, BETTY | reporter.nih.gov |
| Advancing cross-disease comparisons through FAIR data practices to uncover shared molecular mechanisms between Alzheimer's disease and autoimmune disorders | NIH | National Institute on Aging | 2021 to 2025 | $14,514,376 | September 1, 2025 | April 30, 2027 | HEATH, LAURA MICHELLE | reporter.nih.gov |
| SLE Treatment with N-acetylcysteine | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $5,581,470 | June 15, 2020 | May 31, 2027 | PERL, ANDRAS | reporter.nih.gov |
| Lupus Omics Cutaneous Kidney Investigative Team (LOCKIT) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $5,148,251 | March 21, 2022 | December 31, 2026 | BUYON, JILL P | reporter.nih.gov |
| Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $5,112,288 | May 1, 2019 | April 30, 2029 | PASCUAL, MARIA VIRGINIA | reporter.nih.gov |
| Determinants of follicular helper T cell expansion in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $4,994,422 | July 8, 2020 | July 31, 2029 | MOREL, LAURENCE | reporter.nih.gov |
| The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $4,768,587 | July 15, 2022 | April 30, 2027 | BRUNNER, HERMINE I | reporter.nih.gov |
| Unified and fair multimodal representation learning for autoimmune diseases | NIH | Office of the Director, National Institutes of Health | 2024 to 2025 | $4,435,452 | September 16, 2024 | September 15, 2026 | SHEIKH, SAIRA Z | reporter.nih.gov |
| Predictive drivers of new onset, relapse, and progression of human autoimmunity in skin | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $4,237,221 | April 20, 2023 | March 31, 2026 | HARRIS, JOHN E | reporter.nih.gov |
| Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,125,381 | May 1, 2021 | April 30, 2027 | GAFFNEY, PATRICK M | reporter.nih.gov |
| Mechanisms of New-Onset Autoimmunity/Longitudinal Immune Systems Analysis (MONA-LISA) | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $4,017,799 | March 22, 2023 | February 29, 2028 | KARP, DAVID R | reporter.nih.gov |
| Autoimmune Drivers and Protectors Team Science (ADAPTS) | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,860,822 | March 1, 2023 | February 29, 2028 | JAMES, JUDITH A | reporter.nih.gov |
| Regulators of immune complex mediated neutrophil antigen presentation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,580,976 | September 30, 1999 | February 28, 2027 | MAYADAS, TANYA N | reporter.nih.gov |
| Epigenetics of the autoantibody response in systemic lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,576,652 | September 24, 2021 | August 31, 2026 | CASALI, PAOLO | reporter.nih.gov |
| Functional and Mechanistic Characterization of Lupus Susceptibility | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $3,364,935 | September 3, 2025 | August 31, 2029 | NATH, SWAPAN K. | reporter.nih.gov |
| Chemoproteomic-Enabled Strategy to Study SLC Transporter Roles in Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,147,169 | July 1, 2021 | June 30, 2026 | PARKER, CHRISTOPHER G | reporter.nih.gov |
| The Relationship Between Brain Macrophages and Cognitive Dysfunction in Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,138,464 | July 5, 2022 | June 30, 2027 | CUDA, CARLA M | reporter.nih.gov |
| Resolving the mechanisms of IFIH1 risk variant in systemic lupus erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $3,130,679 | September 3, 2025 | August 31, 2029 | GORMAN, JACQUELYN | reporter.nih.gov |
| Manufacturing RNA-based CAR T cells to combat autoantibody-associated autoimmune disorders (AAAD) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $2,992,236 | June 7, 2024 | May 31, 2026 | STEWART, CHARLES ANDREW | reporter.nih.gov |
| Pyrimidine metabolism in the development of autoreactive B cells and SLE | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $2,989,958 | September 1, 2025 | August 31, 2029 | RAHMAN, ZIAUR | reporter.nih.gov |
| Proteomic analysis of hydroxychloroquine prevention trials in T1D, RA and SLE | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $2,978,715 | August 18, 2023 | July 31, 2028 | BUCKNER, JANE HOYT | reporter.nih.gov |
| A phospho-tyrosine-based signaling module controlling TLR-mediated inflammatory disease. | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,936,823 | July 7, 2022 | June 30, 2027 | HAECKER, HANS | reporter.nih.gov |
| ABIN1 dysfunction in Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,909,013 | September 1, 2021 | June 30, 2027 | POWELL, DAVID W. | reporter.nih.gov |
| The Biogenesis of Platelet-Derived Extracellular Vesicles and their Impact on Megakaryocyte Maturation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,874,833 | April 20, 2021 | March 31, 2027 | MACHLUS, KELLIE RAE | reporter.nih.gov |
| Stopping Hydroxychloroquine In Elderly Lupus Disease (SHIELD) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $2,866,312 | August 17, 2023 | July 31, 2028 | IZMIRLY, PETER | reporter.nih.gov |
| TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,853,080 | July 10, 2020 | June 30, 2026 | LUND, FRANCES E. | reporter.nih.gov |
| Role of mitochondria in SLE and its cardiovascular complications | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,831,874 | August 25, 2021 | June 30, 2026 | LOOD, JAN CHRISTIAN | reporter.nih.gov |
| Impact of Loss-of-function NADPH Oxidase Variants on B cell Activation in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,822,766 | February 1, 2021 | December 31, 2025 | JACKSON, SHAUN WILLIAM | reporter.nih.gov |
| BCAP regulation of TLR7/9 signaling in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,809,161 | December 1, 2019 | November 30, 2025 | HAMERMAN, JESSICA A | reporter.nih.gov |
| Monitoring Disease in Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,798,512 | March 8, 2019 | June 30, 2029 | MOHAN, CHANDRA | reporter.nih.gov |
| Harnessing the anti-inflammatory activity of extracellular sialylation of IgG. | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,749,084 | April 16, 2021 | March 31, 2026 | ANTHONY, ROBERT MCCULLOUGH | reporter.nih.gov |
| Pathobiology of ANCA Glomerulonephritis: Targeting Adaptive and Innate Immune Processes for Precision Therapies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,693,358 | July 1, 2020 | May 31, 2025 | FALK, RONALD J | reporter.nih.gov |
| A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE) | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $2,684,733 | August 1, 2024 | May 31, 2027 | GILKESON, GARY S | reporter.nih.gov |
| Mechanisms of sphingolipid signaling in vascular health and disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,673,681 | January 18, 2017 | December 31, 2023 | HLA, TIMOTHY TUN | reporter.nih.gov |
| Unraveling the molecular mechanisms of impaired central tolerance in COPA syndrome | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,664,560 | March 1, 2022 | February 28, 2027 | SHUM, ANTHONY | reporter.nih.gov |
| Administrative Supplement to Investigate the Effects of Long COVID on SELA study participants | NIH | National Institute on Minority Health and Health Disparities | 2021 to 2024 | $2,657,323 | July 28, 2021 | April 30, 2026 | RAMOS, PAULA SOFIA | reporter.nih.gov |
| Lymphatic regulation of lymph node function in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,639,789 | February 1, 2010 | January 31, 2028 | LU, THERESA T. | reporter.nih.gov |
| Development of Immune Tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,613,354 | March 15, 2016 | February 28, 2027 | FARRAR, MICHAEL ARCHIBALD | reporter.nih.gov |
| Neutrophil plasticity in autoimmune disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,593,636 | February 10, 2020 | January 31, 2026 | MAYADAS, TANYA N | reporter.nih.gov |
| Functional consequences of intergenic autoimmune disease risk variants | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,539,964 | March 3, 2023 | February 29, 2028 | NIEWOLD, TIMOTHY B | reporter.nih.gov |
| Expanded Double Negative T cells in SLE. | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,529,548 | May 1, 2010 | May 31, 2026 | TSOKOS, GEORGE C | reporter.nih.gov |
| The role of TLRs, Type II IFN and Type III IFN in a Murine Model of Autoinflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,474,645 | March 19, 2021 | February 28, 2026 | MARSHAK-ROTHSTEIN, ANN | reporter.nih.gov |
| Pathogenesis of Lupus Nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,451,240 | May 6, 2020 | April 30, 2025 | CRAFT, JOSEPH EDGAR | reporter.nih.gov |
| SYK and ZAP70 kinases in lymphocyte selection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,450,839 | February 1, 2022 | January 31, 2027 | MÜSCHEN, MARKUS | reporter.nih.gov |
| Genetic Linkage in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,409,142 | July 1, 1987 | May 31, 2027 | KOTTYAN, LEAH CLAIRE | reporter.nih.gov |
| Role of alveolar macrophage in omega-3 fatty acid amelioration of silica-triggered autoimmunity. | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $2,397,078 | June 1, 2017 | October 31, 2027 | PESTKA, JAMES J | reporter.nih.gov |
| Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,372,392 | February 1, 2022 | January 31, 2027 | COLONNA, MARCO | reporter.nih.gov |
| Origin and Function of Double Negative T cells in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,344,269 | November 19, 2020 | October 31, 2025 | RANDALL, TROY D | reporter.nih.gov |
| Sex and gender differences in lupus - intersection between immunometabolism, epigenetic remodeling and cardiac involvement | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,327,472 | August 16, 2021 | July 31, 2025 | JEFFERIES, CAROLINE | reporter.nih.gov |
| Mechanisms of DNA-Specific Autoimmunity in Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,322,594 | June 1, 2018 | September 30, 2025 | REIZIS, BORIS | reporter.nih.gov |
| Type I Interferon induction of neuroinflammation mediates neuropsychiatric lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,321,217 | August 18, 2025 | July 31, 2028 | CARROLL, MICHAEL CRAIG | reporter.nih.gov |
| Evolution of autoreactive GC and epitope spreading in lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,299,924 | July 13, 2018 | June 30, 2028 | CARROLL, MICHAEL CRAIG | reporter.nih.gov |
| Aberrant DNA Repair and Lupus | NIH | National Institute of Environmental Health Sciences | 2021 to 2023 | $2,286,049 | July 6, 2020 | March 31, 2024 | SWEASY, JOANN B. | reporter.nih.gov |
| Mechanisms controlling ABC differentiation and function in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,285,313 | July 1, 2022 | May 31, 2027 | PERNIS, ALESSANDRA B | reporter.nih.gov |
| Immunogenomics and Systems Biology Core | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,270,385 | March 18, 2022 | December 31, 2026 | GUDJONSSON, JOHANN ELI | reporter.nih.gov |
| Investigating How TLR7 Activates and TLR9 Regulates Systemic Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,270,215 | May 1, 2021 | April 30, 2026 | SHLOMCHIK, MARK J | reporter.nih.gov |
| Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $2,249,923 | February 1, 2017 | January 31, 2025 | OLSEN, NANCY J | reporter.nih.gov |
| Leveraging Community-Academic Partnerships and Social Networks to Disseminate Vaccine-Related Information and Increase Vaccine Uptake Among Black Individuals with Rheumatic Diseases | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $2,239,160 | May 10, 2022 | April 1, 2025 | RAMSEY-GOLDMAN, ROSALIND | reporter.nih.gov |
| Mechanisms driving extrafollicular polyreactive B cell lineages in partial RAG deficiency | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,232,177 | September 22, 2021 | August 31, 2027 | WALTER, JOLAN ESZTER | reporter.nih.gov |
| Contributions of autophagy-related genes in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,228,235 | August 18, 2023 | July 31, 2027 | NATH, SWAPAN K. | reporter.nih.gov |
| Targeting Tfh Cell Metabolic Regulation in SLE and SLE-Associated Atherosclerosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,227,644 | May 20, 2020 | April 30, 2026 | RATHMELL, JEFFREY C. | reporter.nih.gov |
| Genome and Phenome to Define Disease Risk with Antinuclear Antibodies | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,195,635 | April 14, 2020 | March 31, 2026 | KAWAI, VIVIAN K | reporter.nih.gov |
| Role of microbiota-TLR7/8 Interaction in systemic lupus erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,185,400 | November 6, 2018 | October 31, 2025 | VASU, CHENTHAMARAKSHAN | reporter.nih.gov |
| Biochemical and functional characterization of a novel anti-inflammatory biogenic amine | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,177,069 | July 6, 2023 | June 30, 2028 | SANTAMBROGIO, LAURA | reporter.nih.gov |
| The HOP-STEP Intervention: Improving Maternal Health in Women with Lupus through Improved Pregnancy Prevention and Planning | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $2,137,460 | September 22, 2022 | August 31, 2025 | CLOWSE, MEGAN E.B. | reporter.nih.gov |
| Early Pathogenic Steps in Xenobiotic-Induced Autoimmunity | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $2,123,849 | February 24, 2022 | November 30, 2026 | POLLARD, KENNETH MICHAEL | reporter.nih.gov |
| Synergistic effects of silica exposure, virus infection and genetic predisposition in systemic autoimmunity | NIH | National Institute of Environmental Health Sciences | 2021 to 2024 | $2,115,803 | May 1, 2021 | April 30, 2026 | BACCALA, ROBERTO G | reporter.nih.gov |
| Immune Responses in Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,105,156 | August 31, 1990 | April 30, 2027 | CRAFT, JOSEPH EDGAR | reporter.nih.gov |
| CO-LEADER: Intervention to Improve Patient-Provider Communication and Medication Adherence among Patients with Systemic Lupus Erythematosus | NIH | National Institute on Minority Health and Health Disparities | 2023 to 2025 | $2,093,554 | September 23, 2023 | March 31, 2028 | SUN, KAI | reporter.nih.gov |
| Integrative approaches to understand systemic lupus erythematosus etiology in trans-ancestry genetic studies | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,087,518 | September 20, 2022 | July 31, 2027 | LIU, DAJIANG | reporter.nih.gov |
| Clinical applications of urine proteomics to lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,082,416 | March 1, 2023 | December 31, 2027 | FAVA, ANDREA | reporter.nih.gov |
| Identification and Functional Characterization of Bioactive Microbial Metabolites of Beta-Glucan Degradation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,060,432 | June 15, 2023 | April 30, 2028 | VASU, CHENTHAMARAKSHAN | reporter.nih.gov |
| Building Interdisciplinary Research Careers in Women's Health | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $2,059,510 | September 26, 2002 | April 30, 2027 | HARTMANN, KATHERINE E | reporter.nih.gov |
| Characterization of SLE-susceptibility loci on mouse chromosome 1 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,016,564 | June 1, 1999 | May 31, 2029 | MOREL, LAURENCE | reporter.nih.gov |
| Molecular mechanisms of Salmonella mediated autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,975,400 | June 1, 2020 | May 31, 2025 | TUKEL, CAGLA | reporter.nih.gov |
| Regulation of TLR trafficking for proper self versus non-self discrimination | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,952,316 | February 1, 2008 | December 31, 2028 | BARTON, GREGORY M | reporter.nih.gov |
| Metabolic Control of Systemic Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,944,000 | February 1, 2008 | February 28, 2026 | PERL, ANDRAS | reporter.nih.gov |
| Epigenome-Guided Causal Variant Discovery and Mechanisms | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,915,395 | May 6, 2019 | April 30, 2025 | GAFFNEY, PATRICK M | reporter.nih.gov |
| B cell costimulatory signals in the pathogenesis of SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,899,404 | August 1, 2019 | June 30, 2024 | JACKSON, SHAUN WILLIAM | reporter.nih.gov |
| Hippo signaling as a critical regulator of lupus keratinocyte dysfunction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,887,812 | August 2, 2022 | May 31, 2027 | KAHLENBERG, JOANNE MICHELLE | reporter.nih.gov |
| A Phase II Controlled Trial of Allogeneic Mesenchymal Stem Cells for the Treatment of Refractory Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,880,006 | March 19, 2018 | July 31, 2024 | GILKESON, GARY S | reporter.nih.gov |
| Can hydroxychloroquine prevent preeclampsia and preterm delivery in lupus pregnancy? | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,863,630 | August 1, 2020 | May 31, 2026 | SIMARD, JULIA F | reporter.nih.gov |
| NLRP3 Inflammasome Activation, T Follicular Helper Cells and Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,855,554 | September 1, 2020 | August 31, 2025 | SUNG, SUN-SANG JOSEPH | reporter.nih.gov |
| Targeting follicular helper CD4 T cells in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,854,497 | December 1, 2016 | June 30, 2027 | MOREL, LAURENCE | reporter.nih.gov |
| Objective Classification of Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,850,918 | August 20, 2023 | May 31, 2028 | MOHAN, CHANDRA | reporter.nih.gov |
| Dissecting the heterogeneity and function of myeloid cells in lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,838,860 | February 1, 2023 | December 31, 2027 | DAVIDSON, ANNE | reporter.nih.gov |
| Discovery of cGAS Inhibitors for Interferon-Driven Autoimmune Diseases | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,821,270 | June 12, 2019 | July 31, 2023 | LOWERY, ROBERT G | reporter.nih.gov |
| Engineering the next generation nanoparticle-cyclosporine A therapy in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,811,188 | September 21, 2020 | August 31, 2027 | MAJETI, RAVIKUMAR N | reporter.nih.gov |
| Gene Transcription in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,792,539 | April 15, 2002 | May 31, 2028 | TSOKOS, GEORGE C | reporter.nih.gov |
| Commercialization Readiness of Immune Mediator Based Blood Tests that Inform Concurrent and Future Clinical Disease Activity in Systemic Lupus Erythematosus (SLE) | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,790,280 | June 25, 2024 | May 31, 2027 | MUNROE, MELISSA E | reporter.nih.gov |
| Role of the gender biased transcription factor VGLL3 in promoting autoimmune responses in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,783,410 | March 6, 2017 | July 31, 2027 | GUDJONSSON, JOHANN ELI | reporter.nih.gov |
| The Role of the Adrb3/IL6 Axis in the Impact of Psychosocial Stress on Lupus Pathogenesis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,765,880 | February 1, 2022 | December 31, 2026 | WANG, ANDREW | reporter.nih.gov |
| T cells in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,750,000 | December 1, 2019 | November 30, 2024 | TSOKOS, GEORGE C | reporter.nih.gov |
| ARID3a functions in autoimmune B cells | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $1,749,245 | September 4, 2025 | August 31, 2029 | WEBB, CAROL F | reporter.nih.gov |
| Plasmacytoid dendritic cells and IgA autoantibodies in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,707,941 | June 12, 2024 | April 30, 2029 | HAMERMAN, JESSICA A | reporter.nih.gov |
| Treatment of lupus nephritis with nanoparticles that selectively target kidney glomeruli | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,690,800 | April 1, 2023 | March 31, 2028 | LIU, RUISHENG | reporter.nih.gov |
| Platelet Activity and Vascular Health in Systemic Lupus Erythematosus | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,681,304 | January 1, 2018 | November 30, 2023 | BERGER, JEFFREY S | reporter.nih.gov |
| Interrogating The Biology Of Human Lupus Nephritis Using Single Cell Resolution Spatial Transcriptomics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,676,789 | April 1, 2024 | January 31, 2028 | JACKSON, SHAUN WILLIAM | reporter.nih.gov |
| Effectiveness of the HPV Vaccine in Immunocompromised Populations | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,654,519 | July 9, 2024 | May 31, 2029 | SILVERBERG, MICHAEL J | reporter.nih.gov |
| Role for nuclear matrix proteins and DNA methylation for XCI maintenance in female lymphocytes | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,647,188 | July 7, 2023 | June 30, 2028 | ANGUERA, MONTSERRAT C | reporter.nih.gov |
| Alteration of function and specificity of TFH in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,638,621 | July 5, 2019 | June 30, 2025 | DIAMOND, BETTY | reporter.nih.gov |
| Control of Renal Inflammation in Hypertension | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,624,098 | May 14, 2021 | July 15, 2023 | MATHIS, KEISA WILLIAMS | reporter.nih.gov |
| Gene regulation mechanisms involving the inactive X in B cells during lupus disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,621,050 | June 1, 2018 | August 31, 2030 | ANGUERA, MONTSERRAT C | reporter.nih.gov |
| Aberrant DNA Repair and Lupus | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $1,618,709 | July 6, 2020 | March 31, 2028 | SWEASY, JOANN B. | reporter.nih.gov |
| miR-21 regulation of autoreactive B cell and lupus nephritis development | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,615,554 | July 18, 2022 | June 30, 2027 | RAHMAN, ZIAUR | reporter.nih.gov |
| IRF7-mediated development of autoreactive B cells and SLE | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,608,987 | June 23, 2021 | May 31, 2027 | RAHMAN, ZIAUR | reporter.nih.gov |
| Implicit Bias in the Evidence: An Evaluation of Female-Predominant Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,603,449 | September 22, 2020 | August 31, 2025 | SIMARD, JULIA F | reporter.nih.gov |
| Characterization of interferon kappa as a novel target in cutaneous lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,600,870 | September 21, 2017 | April 30, 2029 | KAHLENBERG, JOANNE MICHELLE | reporter.nih.gov |
| Role of the L1 retrotransposon in interferon-positive SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,597,570 | April 21, 2022 | March 31, 2028 | MUSTELIN, TOMAS M | reporter.nih.gov |
| Neonatal Fc Receptor (FcRn) Trafficking of Immune Complexes to the Lysosome as a Driver of Glomerulonephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,594,114 | September 1, 2015 | November 30, 2025 | BLAINE, JUDITH T., | reporter.nih.gov |
| Mapping the cell-type-specific molecular and genetic basis of lupus using single cell multiomics | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,590,771 | February 1, 2024 | December 31, 2028 | YE, CHUN JIMMIE | reporter.nih.gov |
| The Role of Estrogen Receptor Alpha Variant Size and Localization in Modulating TLR7-Induced Inflammation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,579,168 | February 14, 2022 | December 31, 2026 | CUNNINGHAM, MELISSA A | reporter.nih.gov |
| Nonreceptor tyrosine kinases in Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,578,185 | May 25, 2021 | April 30, 2027 | MILLER, W TODD | reporter.nih.gov |
| Upstream drivers of type I interferons in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,555,112 | May 28, 2024 | March 31, 2029 | MUSTELIN, TOMAS M | reporter.nih.gov |
| Using artificial intelligence to bridge human and murine studies of lupus nephritis progression | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,554,456 | August 15, 2024 | July 31, 2029 | CLARK, MARCUS RAMSAY | reporter.nih.gov |
| Mechanisms of BNT162b2 Vaccine Immunogenicity in Systemic Lupus Erythematosus or Scleroderma | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,492,035 | March 4, 2024 | January 31, 2029 | UTZ, PAUL JOSEPH | reporter.nih.gov |
| Translating oral CD11b agonist as a novel therapeutic for lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,483,164 | September 20, 2011 | June 30, 2029 | GUPTA, VINEET | reporter.nih.gov |
| Langerhans cells and lymphatic regulation in immunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,480,392 | August 1, 2024 | July 31, 2029 | LU, THERESA T. | reporter.nih.gov |
| Intrinsic B cell epigenetic regulation of antibody and autoantibody responses by Sirt1 | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,423,069 | June 14, 2013 | January 31, 2026 | CASALI, PAOLO | reporter.nih.gov |
| Role of beta2 integrin in lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,417,782 | September 20, 2011 | November 30, 2023 | GUPTA, VINEET | reporter.nih.gov |
| STTR Phase II: Advance Early Detection of Lupus Nephritis with ClearGold | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,415,110 | September 19, 2019 | August 31, 2025 | YU, MENGXIAO | reporter.nih.gov |
| Role of DNA methylation in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,406,955 | February 25, 2013 | July 31, 2025 | SAWALHA, AMR H | reporter.nih.gov |
| Transancestral fine mapping and functional dissection of autophagy-related SLE risk loci | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,374,340 | April 9, 2018 | February 28, 2024 | TSAO, BETTY P | reporter.nih.gov |
| Targeting ferroptosis in renal tubular epithelial cells to improve outcomes of lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,360,107 | April 1, 2023 | January 31, 2028 | SCINDIA, YOGESH | reporter.nih.gov |
| A new paradigm of glomerular immune cell homing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,358,421 | December 15, 2022 | November 30, 2026 | PETI-PETERDI, JANOS | reporter.nih.gov |
| Pathogenic role of innate immune cells in lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,342,551 | May 3, 2019 | April 30, 2025 | HAECKER, HANS | reporter.nih.gov |
| Transcription Factor Genetics in Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,332,575 | April 1, 2019 | March 31, 2025 | KOTTYAN, LEAH CLAIRE | reporter.nih.gov |
| Mechanisms of iron-mediated renal injury in lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,331,974 | March 9, 2020 | January 31, 2026 | BOESEN, ERIKA INGRID | reporter.nih.gov |
| Novel Therapeutic Approaches for Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,322,724 | July 1, 2020 | May 31, 2025 | THURMAN, JOSHUA M | reporter.nih.gov |
| Digital Pathology and Computational Image Analysis for Lupus Nephritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,322,062 | March 5, 2024 | January 31, 2029 | HODGIN, JEFFREY BENTON | reporter.nih.gov |
| A biomarker panel based smart mini-array system for the homecare of autoimmune kidney diseases | NIH | National Institute on Aging | 2021 to 2023 | $1,305,524 | April 1, 2019 | January 31, 2026 | WU, TIANFU | reporter.nih.gov |
| Engineering Polymers to Scavenge DAMPs in Arthritis and Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,303,670 | August 15, 2018 | July 31, 2024 | SULLENGER, BRUCE ALAN | reporter.nih.gov |
| Building Interdisciplinary Research Careers in Women's Health | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,296,001 | September 26, 2002 | April 30, 2027 | VELEZ EDWARDS, DIGNA R | reporter.nih.gov |
| Targeting the long isoform of the prolactin receptor to treat autoimmune diseases and B-cell malignancies | NIH | National Cancer Institute | 2023 to 2025 | $1,292,812 | July 15, 2023 | June 30, 2028 | SWAMINATHAN, SRIVIDYA | reporter.nih.gov |
| T cell regulation of pathogenic B cells in systemic autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,282,104 | February 23, 2024 | January 31, 2029 | WEINSTEIN, JASON | reporter.nih.gov |
| Gut dysbiosis and tryptophan metabolism in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,259,918 | January 19, 2019 | December 31, 2029 | MOREL, LAURENCE | reporter.nih.gov |
| Development of Kv1.3 Monoclonal Antibodies Targeting TEM Cells for Treating Autoimmune Disorders | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $1,223,786 | September 5, 2014 | September 30, 2024 | RUCKER, JOSEPH BENJAMIN | reporter.nih.gov |
| Quantitative Analysis of Serum Autoantibody Repertories in Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,213,876 | November 15, 2018 | October 31, 2024 | SINGH, SHANTERI | reporter.nih.gov |
| Mechanisms of genetic variants in TH2 autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,212,458 | July 5, 2024 | May 31, 2029 | GORONZY, JORG J | reporter.nih.gov |
| Predictive Biomarkers for disease activity and organ damage in patients with lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,211,313 | May 27, 2018 | April 30, 2024 | TSAO, BETTY P | reporter.nih.gov |
| Improving the Accuracy of Lupus Nephritis Diagnosis using Biomarkers Derived from Ultraviolet and Mid-infrared Spectroscopic Imaging | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,203,168 | January 1, 2024 | November 30, 2028 | REDDY, ROHITH | reporter.nih.gov |
| B cell depletion to prevent autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,187,773 | August 15, 2020 | June 30, 2025 | DHODAPKAR, KAVITA MADHAV | reporter.nih.gov |
| Lupus Intervention Fatigue Trial (LIFT) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,161,234 | August 1, 2018 | July 31, 2024 | RAMSEY-GOLDMAN, ROSALIND | reporter.nih.gov |
| Novel Immunoregulatory Therapeutics for Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $1,127,318 | January 1, 2021 | June 30, 2025 | LEBER, ANDREW | reporter.nih.gov |
| Objective tests utilizing Vibrational Spectroscopy for Diagnosis and Severity of Fibromyalgia and Related Pain Syndromes | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,127,024 | September 15, 2020 | March 31, 2027 | HACKSHAW, KEVIN VICTOR | reporter.nih.gov |
| Control of Renal Inflammation in Hypertension | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,125,986 | May 14, 2021 | April 30, 2027 | MATHIS, KEISA W | reporter.nih.gov |
| Understanding the immunometabolic mechanism of VGLL3 mediating female-biased autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,125,088 | January 1, 2022 | March 31, 2027 | LIANG, YUN | reporter.nih.gov |
| Infections, Microbiome and HLA-DR in the Induction of Lupus Related Auto-antibodies | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,089,900 | August 10, 2018 | July 31, 2023 | SUNG, SUN-SANG JOSEPH | reporter.nih.gov |
| Investigating monocyte activation pathways in lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,083,390 | July 19, 2023 | May 31, 2028 | KANG, INSOO | reporter.nih.gov |
| IRF7-mediated development of autoreactive B cells and SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,065,965 | June 23, 2021 | May 31, 2023 | RAHMAN, ZIAUR | reporter.nih.gov |
| FDC regulation of self-reactive B cells | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,062,000 | December 14, 2017 | November 30, 2023 | CARROLL, MICHAEL CRAIG | reporter.nih.gov |
| Gene transcription in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,051,966 | April 15, 2002 | June 14, 2023 | TSOKOS, GEORGE C | reporter.nih.gov |
| Control of B cell differentiation by IFNg induced transcription factors | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,039,868 | February 14, 2014 | November 30, 2025 | LUND, FRANCES E. | reporter.nih.gov |
| Characterization of the lupus nephritis microRNAome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,021,489 | September 7, 2018 | August 31, 2025 | BROWN, ELIZABETH E | reporter.nih.gov |
| Humoral Immunity by Anergic B cells | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,021,128 | July 3, 2018 | June 30, 2024 | TORRES, RAUL MARTIN | reporter.nih.gov |
| Leukocyte NADPH Oxidase Variants in Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,006,597 | August 1, 2017 | April 30, 2024 | JACOB, CHAIM O. | reporter.nih.gov |
| Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $994,978 | August 7, 2025 | July 31, 2028 | SCHULTZ, KENNETH | reporter.nih.gov |
| Epigenetic modulation of CD4+ T cell differentiation and autoimmunity by trichloroethylene | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $988,355 | April 15, 2021 | December 31, 2025 | BLOSSOM, SARAH J | reporter.nih.gov |
| B cell intrinsic interferon-beta regulates autoreactive B cell development | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $967,534 | February 13, 2018 | January 31, 2024 | MOUNTZ, JOHN D | reporter.nih.gov |
| Advancing Quality and Outcomes Measurement in Rheumatology | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $965,394 | February 15, 2019 | November 30, 2028 | YAZDANY, JINOOS | reporter.nih.gov |
| Lysosome Defects and the Accumulation of Immune Complexes in Human Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $959,258 | March 11, 2019 | February 29, 2024 | VILEN, BARBARA J | reporter.nih.gov |
| Phosphatases in Systemic Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $875,000 | September 18, 2018 | August 31, 2024 | TSOKOS, GEORGE C | reporter.nih.gov |
| A Personalized, Patient-Centered Approach to Optimizing Lupus Care | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $874,800 | April 1, 2021 | March 31, 2026 | JORGE, APRIL | reporter.nih.gov |
| Endosomal TLR transport in B cell signaling and autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $870,750 | February 12, 2019 | September 30, 2023 | KONO, DWIGHT H | reporter.nih.gov |
| The Genetics of Silica-Induced Autoimmunity | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $870,750 | August 15, 2018 | December 31, 2023 | POLLARD, KENNETH MICHAEL | reporter.nih.gov |
| Mechanisms of sex discrepancy in autoimmune disease: Regulation of the female-biased VGLL3 immune pathway | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $865,208 | August 1, 2021 | July 31, 2026 | BILLI, ALLISON CHELSA | reporter.nih.gov |
| Critical Translational Studies in Pediatric Nephrology | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $850,000 | September 15, 2017 | August 31, 2023 | DEVARAJAN, PRASAD | reporter.nih.gov |
| Erythropoietin mediated immunoregulation in murine lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $847,500 | February 15, 2018 | January 31, 2023 | CRAVEDI, PAOLO | reporter.nih.gov |
| Role of the transcription factor Ikaros in development of autoimmune disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $847,088 | June 15, 2018 | May 31, 2023 | SCHJERVEN, HILDE | reporter.nih.gov |
| Mechanisms of IL-23 receptor-mediated pathogenicity in CD4+ T cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $844,240 | July 1, 2021 | June 30, 2027 | HO, ALLEN WAYNE | reporter.nih.gov |
| The Exposome in Rheumatoid Arthritis and Systemic Lupus Erythematosus: EXACT Network Planning | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $843,158 | August 18, 2025 | August 31, 2026 | NORRIS, JILL M | reporter.nih.gov |
| Mechanisms of polarization of monocytes by DAMPs/PAMPs and C1q | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $823,782 | June 1, 2018 | May 31, 2024 | SON, MYOUNGSUN | reporter.nih.gov |
| Complement in Human Lupus: Deficiencies, Profiles and Complications | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $813,867 | July 8, 2018 | May 31, 2024 | YU, CHACK Y | reporter.nih.gov |
| Social Factors, Epigenomics and Lupus Assessment (SELA) | NIH | National Institute on Minority Health and Health Disparities | 2025 | $812,824 | July 28, 2021 | June 30, 2027 | RAMOS, PAULA SOFIA | reporter.nih.gov |
| A B-Cell Gene for Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $794,073 | July 6, 2018 | May 31, 2024 | MOHAN, CHANDRA | reporter.nih.gov |
| Defining the Regulatory Landscape of Lupus with CVD Comorbidity | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $793,093 | November 20, 2024 | October 31, 2029 | NATH, SWAPAN K. | reporter.nih.gov |
| Cardiovascular health assessment & outcomes of systemic lupus erythematosus: bridging pediatric and adult- onset disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $788,047 | August 1, 2020 | December 31, 2025 | CHANG, JOYCE CHUN-LING | reporter.nih.gov |
| MAIT cells in lupus skin disease and photosensitivity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $787,043 | May 1, 2023 | April 30, 2028 | SKOPELJA-GARDNER, SLADJANA | reporter.nih.gov |
| Ikaros family genes and lupus susceptibility across ethnically diverse populations | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $781,667 | September 1, 2018 | August 31, 2023 | NATH, SWAPAN K. | reporter.nih.gov |
| Investigating the Repertoires and Functions of T Cells that Help Autoreactive B Cells in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $765,550 | December 22, 2017 | November 30, 2023 | SHLOMCHIK, MARK J | reporter.nih.gov |
| Atrioventricular Block Elimination by Rozanolixizumab Treatment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $755,461 | September 15, 2025 | June 30, 2030 | BUYON, JILL P | reporter.nih.gov |
| Immune system dysfunction and gut dysbiosis in the pathogenesis of vascular dysfunction in autoimmunity | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $747,000 | January 5, 2022 | December 31, 2024 | TAYLOR, ERIN BASSFORD | reporter.nih.gov |
| Burden, correlates, and outcomes of poor cognitive and physical functioning in the lupus population | NIH | National Institute on Aging | 2021 to 2023 | $746,440 | February 15, 2019 | May 31, 2023 | PLANTINGA, LAURA | reporter.nih.gov |
| Development of Immune Mediator Based Blood Tests that Inform Concurrent and Future Clinical Disease Activity in Systemic Lupus Erythematosus (SLE) | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $742,933 | August 1, 2019 | August 31, 2022 | MUNROE, MELISSA E | reporter.nih.gov |
| The Effect of Sodium (Na+) on Kidney B cells in Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $719,391 | September 1, 2022 | August 31, 2027 | CHERNOVA, IRENE | reporter.nih.gov |
| Mechanisms underlying interferon-induced T peripheral helper cell differentiation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $715,957 | March 24, 2025 | April 1, 2025 | CHOI, JAEHYUK | reporter.nih.gov |
| Foxp3 isoform expression and regulation of autoantibody production | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $709,019 | November 19, 2024 | October 31, 2029 | ZIEGLER, STEVEN F | reporter.nih.gov |
| Identify Rare Pathogenic Variants and their Functional Consequences in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $704,424 | August 15, 2025 | July 31, 2030 | TSAO, BETTY P | reporter.nih.gov |
| Ribosomal Skipping Under Oxidative Stress in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $701,455 | July 1, 2018 | June 30, 2024 | KOENIG, IWONA AGNIESZKA | reporter.nih.gov |
| Thromboinflammatory consequences of infection-induced autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $692,543 | August 1, 2022 | July 31, 2027 | ZUO, YU | reporter.nih.gov |
| Linking Disease Mechanisms and Outcomes in Rheumatic Diseases | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $687,452 | July 6, 2020 | May 31, 2030 | KAHLENBERG, JOANNE MICHELLE | reporter.nih.gov |
| Role of VISTA in discoid lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $686,016 | July 1, 2022 | June 30, 2027 | VESELY, MATTHEW D | reporter.nih.gov |
| Functions of LynA and LynB kinases in myeloid-cell pro-inflammatory signaling and lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $668,135 | September 1, 2025 | August 31, 2030 | FREEDMAN, TANYA S. | reporter.nih.gov |
| Mechanistic role of probiotic Lactobacillus reuteri in autoimmune lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $659,756 | March 5, 2018 | January 31, 2024 | LUO, XIN | reporter.nih.gov |
| NK cell-mediated regulation of humoral immune responses during autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $637,018 | August 7, 2025 | June 30, 2030 | WEINSTEIN, JASON | reporter.nih.gov |
| Determinants of follicular helper T cell expansion in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $633,159 | July 8, 2020 | June 30, 2022 | MOREL, LAURENCE | reporter.nih.gov |
| Characterization of Chronic Pain and its Biopsychosocial Mechanisms in Lupus using Electronic Health Records | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $631,260 | May 19, 2021 | April 30, 2026 | FALASINNU, TITILOLA | reporter.nih.gov |
| Targeted Peer Coaching to Reduce Fatigue in Lupus: A Patient-Centered Behavioral Intervention | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $620,441 | September 1, 2021 | August 31, 2026 | KASTURI, SHANTHINI | reporter.nih.gov |
| Follicular Helper T Cell Function in Autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $620,185 | December 10, 2018 | November 30, 2023 | CRAFT, JOSEPH EDGAR | reporter.nih.gov |
| Peer Approaches to Lupus Self-Management (PALS) | NIH | National Institute of Nursing Research | 2021 to 2022 | $617,992 | September 26, 2018 | August 31, 2022 | WILLIAMS, EDITH MARIE | reporter.nih.gov |
| Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $610,850 | June 21, 2023 | May 31, 2025 | SCHULTZ, KENNETH | reporter.nih.gov |
| Characterization of SLE-susceptibility loci on mouse chromosome 1 | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $609,334 | June 1, 1999 | May 31, 2022 | MOREL, LAURENCE | reporter.nih.gov |
| Silencing autoantibody secretion for SLE therapy | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $599,638 | May 8, 2023 | April 30, 2026 | MENDELSOHN, ANDREW R | reporter.nih.gov |
| Gut dysbiosis and tryptophan metabolism in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $592,941 | January 11, 2019 | July 31, 2022 | MOREL, LAURENCE | reporter.nih.gov |
| Autoimmunity-Associated B Cells in Lupus Nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $576,720 | June 16, 2023 | May 31, 2028 | BARNAS, JENNIFER LYNN | reporter.nih.gov |
| miR-21 regulation of autoreactive B cell and lupus nephritis development | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $563,050 | July 18, 2022 | June 30, 2023 | RAHMAN, ZIAUR | reporter.nih.gov |
| Phosphatases in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $558,045 | May 7, 2025 | April 30, 2030 | TSOKOS, GEORGE C | reporter.nih.gov |
| AhR suppression of T-bet+ B cells in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $555,774 | November 19, 2024 | October 31, 2029 | MOUNTZ, JOHN D | reporter.nih.gov |
| Improving the diagnosis and outcome of diffuse alveolar hemorrhage in systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $544,689 | August 6, 2025 | June 30, 2030 | REEVES, WESTLEY H | reporter.nih.gov |
| Autoimmunity, calorie restriction, and core body temperature | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $541,500 | June 17, 2025 | May 31, 2027 | BACCALA, ROBERTO G | reporter.nih.gov |
| Regulation of Lupus by Cytosolic DNA Sensors | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $535,551 | January 10, 2017 | December 31, 2021 | MARSHAK-ROTHSTEIN, ANN | reporter.nih.gov |
| SLE-AWARE: SLE-- A Window into APOL1 Regulation andExpression | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $532,491 | September 20, 2021 | January 15, 2024 | BLAZER, ASHIRA DESHON | reporter.nih.gov |
| Differential role of TASL and SLC15A4 in TLR responses to nucleic acids and lupus development | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $528,000 | November 18, 2022 | October 31, 2025 | BACCALA, ROBERTO G | reporter.nih.gov |
| Engagement and Depression in Adolescents and Young Adults with Childhood-onset Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $522,288 | March 2, 2023 | January 31, 2028 | RUBINSTEIN, TAMAR B | reporter.nih.gov |
| Metabolic control of monocyte development and function by amino acids | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $520,761 | March 1, 2019 | August 31, 2024 | LEE, PUI YUEN | reporter.nih.gov |
| Pathogenic T cells in discoid lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $520,020 | June 1, 2023 | April 30, 2028 | LITTLE, ALICIA | reporter.nih.gov |
| The Role of Interferon Regulatory Factor 5 in the Pathogenesis of SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $519,976 | September 22, 2017 | August 31, 2024 | RIFKIN, IAN R | reporter.nih.gov |
| The Role of TNF in Breaking B Cell Tolerance | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $510,840 | July 1, 2020 | June 30, 2025 | QUACH, TAM D | reporter.nih.gov |
| Evaluating T cell Exhaustion in Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $503,820 | April 1, 2019 | August 31, 2024 | TILSTRA, JEREMY SCOTT | reporter.nih.gov |
| Computational mapping of human B cell migration and differentiation pathways | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $498,000 | August 19, 2022 | August 31, 2025 | HOEHN, KENNETH | reporter.nih.gov |
| IgG glycosylation in lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $498,000 | July 18, 2022 | June 30, 2027 | BHARGAVA, RHEA | reporter.nih.gov |
| Elucidation of the interactome for the bioactive disaccharide Man(B1-4)GlcNAc | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $494,600 | January 8, 2024 | November 30, 2025 | HUANG, MIA L | reporter.nih.gov |
| Cardiovascular Disease Epidemiology in Patients with Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $491,268 | May 15, 2014 | April 30, 2025 | COSTENBADER, KAREN H | reporter.nih.gov |
| HIPK1: a new immunomodulatory target for SLE | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $489,500 | July 25, 2023 | June 30, 2026 | WELLS, ANDREW D | reporter.nih.gov |
| Mechanisms for Human TLR8 induced pregnancy loss in a mouse model of SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $483,708 | June 18, 2021 | May 31, 2024 | DAVIDSON, ANNE | reporter.nih.gov |
| Intracellular complement activation in Lupus Nephritis Podocytes | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $481,250 | February 6, 2021 | January 31, 2024 | SATYAM, ABHIGYAN | reporter.nih.gov |
| Connecting the gap between GWAS and functional targets for lupus susceptibility | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $480,700 | May 5, 2022 | April 30, 2025 | NATH, SWAPAN K. | reporter.nih.gov |
| Foxp3DEx2 isoform expression leads to Treg dysfunction and SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $478,775 | March 3, 2021 | August 31, 2023 | ZIEGLER, STEVEN F | reporter.nih.gov |
| Identifying autoimmune associated genes in patrolling monocytes that promote lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $476,575 | July 1, 2023 | December 31, 2025 | HAMERMAN, JESSICA A | reporter.nih.gov |
| Foxp3 isoforms and IgE-mediated UVB-induced skin inflammation expression | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $476,575 | May 22, 2023 | April 30, 2025 | ZIEGLER, STEVEN F | reporter.nih.gov |
| Regulation of Tfh function in autoimmunity by TSLP | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $476,076 | February 1, 2022 | January 31, 2024 | ZIEGLER, STEVEN F | reporter.nih.gov |
| A novel regulator of extracellular nucleic acid sensing | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $466,125 | March 16, 2021 | February 28, 2023 | REIZIS, BORIS | reporter.nih.gov |
| Role of SCARF1 in removal of apoptotic debris and protection against autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $460,625 | May 24, 2021 | April 30, 2024 | RAMIREZ-ORTIZ, ZAIDA GISELA | reporter.nih.gov |
| Thromboinflammatory pathways triggered by gut dysbiosis in patients with Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $459,769 | December 1, 2023 | October 31, 2026 | SILVERMAN, GREGG JOSHUA | reporter.nih.gov |
| Regulation of lupus pathogenesis through modulation of thymic development of pathobiont-specific T cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $455,488 | December 1, 2023 | November 30, 2026 | ZEGARRA RUIZ, DANIEL FERNANDO | reporter.nih.gov |
| Novel anti-CD19 CAR-T cells for lupus nephritis treatment | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $453,750 | June 18, 2021 | May 31, 2024 | CHEN, SI-YI | reporter.nih.gov |
| Detailed molecular and structural characterization of the meninges: an approach combining proteomics and Imaging Mass Cytometry | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $451,000 | February 1, 2022 | January 31, 2025 | PACHTER, JOEL S | reporter.nih.gov |
| T-bet expressing B cells in autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $450,688 | April 1, 2021 | March 31, 2024 | SATTERTHWAITE, ANNE B | reporter.nih.gov |
| Transcription factor A mitochondria in SLE pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $450,313 | February 22, 2022 | January 31, 2025 | ANDRADE, FELIPE | reporter.nih.gov |
| LINE1-ORF0 in SLE pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $450,313 | February 6, 2023 | January 31, 2026 | ANDRADE, FELIPE | reporter.nih.gov |
| Precision immunotherapies targeting the 9G4 idiotype in lupus erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $450,313 | February 1, 2023 | January 31, 2026 | KONIG, MAXIMILIAN FERDINAND | reporter.nih.gov |
| Directing Cytokine Specificity Through Co-translational Carrier Coupling | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $449,459 | November 8, 2022 | October 31, 2024 | HUANG, YINA HSING | reporter.nih.gov |
| Skin-lymph node axis in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $446,026 | July 15, 2022 | June 30, 2024 | LU, THERESA T. | reporter.nih.gov |
| Izumo1 in remission in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $444,172 | February 8, 2024 | December 31, 2026 | ANDRADE, FELIPE | reporter.nih.gov |
| The antigenic origin of anti-dsDNA antibodies in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $444,172 | February 1, 2024 | December 31, 2026 | ANDRADE, FELIPE | reporter.nih.gov |
| Tracking Extracellular Vesicles Derived From B Cells in Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $444,125 | January 12, 2022 | December 31, 2023 | ERICKSON, LOREN D | reporter.nih.gov |
| Variants underlying sex bias in Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $441,981 | November 1, 2021 | October 31, 2024 | CARREL, LAURA | reporter.nih.gov |
| FOXP3 ΔE2 Isoform in Treg Function and Pathophysiology of Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $435,875 | April 12, 2021 | March 31, 2024 | ZHOU, BAOHUA | reporter.nih.gov |
| Potential of tissue kallikreins as therapeutic targets for neuropsychiatric lupus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $435,875 | January 1, 2023 | December 31, 2025 | SRIRAM, UMA | reporter.nih.gov |
| Targeting GPR109A for the treatment of pain in systemic lupus erythematosus | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $435,185 | October 1, 2018 | May 31, 2025 | WENG, HAN-RONG | reporter.nih.gov |
| Engineered DNA-particles to model immune events in systemic lupus erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $434,743 | July 3, 2023 | June 30, 2025 | PAYNE, CHRISTINE K | reporter.nih.gov |
| Targeting Aberrant Expression of Cytokines/Chemokines for an Inflammatory Nephritis Cure | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $433,125 | June 22, 2022 | May 31, 2026 | LIN, PEI-HUI | reporter.nih.gov |
| Investigation of Epigenetic Dysregulation in Lupus NK Cells | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $433,075 | March 3, 2021 | February 29, 2024 | UTZ, PAUL JOSEPH | reporter.nih.gov |
| Regulation of the follicular T-cell response to autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $429,521 | April 1, 2000 | November 30, 2022 | CANTOR, HARVEY | reporter.nih.gov |
| cGAMP as an immunotransmitter of the interferon response to UV light | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $427,130 | September 23, 2021 | August 31, 2023 | ELKON, KEITH B. | reporter.nih.gov |
| Delineating the function of MHC class III genes in antigen presenting myeloid cell contribution to autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $426,250 | June 9, 2022 | May 31, 2024 | LIPSCOMB, MICHAEL W | reporter.nih.gov |
| Splenic Modulation of SHP-2 Activity as a Therapeutic Option for Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $424,886 | March 1, 2023 | October 31, 2025 | MCCARTHY, JASON R. | reporter.nih.gov |
| Biobehavioral Basis and Outcomes of Cognitive Dysfunction in Childhood-Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $424,059 | September 1, 2024 | August 31, 2027 | UPADHYAY, JAYMIN A | reporter.nih.gov |
| Development of novel antibodies to autoreactive B cells as a potential therapeutic for SLE patients | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $423,500 | June 25, 2025 | May 31, 2027 | KALININA, OLGA | reporter.nih.gov |
| Leaky gut drives autoimmunity via bacterial flagellin-mediated activation of TLR5 | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $420,066 | May 21, 2021 | April 30, 2024 | LUO, XIN | reporter.nih.gov |
| Concurrent eradication of pathogenic plasma cells and their precursors in systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $415,414 | September 18, 2024 | August 31, 2026 | SWAMINATHAN, SRIVIDYA | reporter.nih.gov |
| Non-tuberculous Mycobacteria as triggers of Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $413,860 | July 23, 2025 | June 30, 2027 | OLIVE, ANDREW | reporter.nih.gov |
| Nucleic acid-containing immune complexes and immune activation | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $408,200 | August 1, 2024 | June 30, 2026 | FORTHAL, DONALD N | reporter.nih.gov |
| Mechanisms of altered T cell epigenetics in lupus | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $406,250 | January 19, 2022 | December 31, 2023 | LAUFER, TERRI M. | reporter.nih.gov |
| Role of Lipid Droplets in Macrophages and their Consequences in Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $405,350 | September 23, 2024 | August 31, 2026 | SON, MYOUNGSUN | reporter.nih.gov |
| Divergence of V-region sequences from the human proteome as a factor in autoimmune diseases and the immunogenicity of therapeutic antibodies. | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $401,693 | December 1, 2023 | October 31, 2026 | SCHROEDER, HARRY WILLIAM | reporter.nih.gov |
| IRAK4 and Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $398,750 | June 15, 2018 | May 31, 2023 | VELLA, ANTHONY T | reporter.nih.gov |
| Effector functions and cellular targets of pathogenic plasmacytoid cells in lupus. | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $396,250 | December 1, 2016 | November 30, 2022 | JORGENSEN, TRINE NORGAARD | reporter.nih.gov |
| SLE-AWARE: SLE-- A Window into APOL1 Regulation andExpression | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $395,280 | September 20, 2021 | August 31, 2027 | BLAZER, ASHIRA DESHON | reporter.nih.gov |
| T cell regulation of pathogenic B cell in systemic autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $392,539 | September 19, 2018 | July 31, 2023 | WEINSTEIN, JASON | reporter.nih.gov |
| Molecular chaperones and immune tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $387,495 | March 1, 2009 | February 28, 2023 | LI, ZIHAI | reporter.nih.gov |
| MAIT cells in lupus skin disease and photosensitivity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $387,047 | May 1, 2023 | April 30, 2024 | SKOPELJA-GARDNER, SLADJANA | reporter.nih.gov |
| TLR Transporters in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $387,000 | August 28, 2018 | July 31, 2022 | KONO, DWIGHT H | reporter.nih.gov |
| VISTA regulates type I interferon response to ultraviolet light | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $384,002 | September 24, 2021 | August 31, 2023 | SKOPELJA-GARDNER, SLADJANA | reporter.nih.gov |
| Role of TXLNA in cytosolic DNA-mediated innate immunity | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $382,500 | June 20, 2025 | May 31, 2030 | LI, SHITAO | reporter.nih.gov |
| Targeting follicular helper CD4 T cells in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $381,250 | December 1, 2016 | July 17, 2022 | MOREL, LAURENCE | reporter.nih.gov |
| Tablet-Based Physical Activity Intervention for Frail and Pre-Frail Older Adults with Systemic Lupus Erythematosus | NIH | National Institute on Aging | 2024 to 2025 | $381,203 | August 15, 2024 | May 31, 2029 | LIEBER, SARAH BETH | reporter.nih.gov |
| PATHOGENESIS OF PRISTANE-INDUCED LUPUS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $379,760 | September 30, 1997 | August 31, 2023 | REEVES, WESTLEY H | reporter.nih.gov |
| TFEB and age-associated B cells in autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $377,273 | September 5, 2025 | August 31, 2027 | ZENG, HU | reporter.nih.gov |
| Delineating the interplay between nucleic-acid-dependent phase separation and immune responses against cGAS in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $375,100 | September 20, 2024 | August 31, 2026 | ANTIOCHOS, BRENDAN | reporter.nih.gov |
| Pregnancy and cardiovascular health in caring for women with systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $372,210 | September 15, 2025 | August 31, 2029 | HOWARDS, PENELOPE P. | reporter.nih.gov |
| Diversification of Glomerular Kidney Disease Treatments By Targeting Therapeutics to the Kidney | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $367,900 | September 22, 2023 | September 14, 2025 | JOY, MELANIE S | reporter.nih.gov |
| TRIM21 as a regulator of UVB- and cytosolic DNA-driven IFN responses in lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $367,400 | September 23, 2022 | August 31, 2024 | JEFFERIES, CAROLINE | reporter.nih.gov |
| The role of human SLE causal variant NCF1.pR90H in promoting kidney damage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $365,420 | September 23, 2023 | August 31, 2025 | TSAO, BETTY P | reporter.nih.gov |
| Low density neutrophils and lupus | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $362,500 | December 8, 2022 | November 30, 2024 | WEBB, CAROL F | reporter.nih.gov |
| Gene-Environment Collaboration in Autoimmune Disease | NIH | National Institute of Environmental Health Sciences | 2021 | $362,250 | September 30, 2017 | August 31, 2023 | FOSTER, MARY H. | reporter.nih.gov |
| Physical Activity Behaviors and Readiness for a Digital Health Physical Activity Intervention inOlder Adults with Systemic Lupus Erythematosus | NIH | National Institute on Aging | 2023 to 2024 | $361,640 | September 5, 2023 | May 31, 2026 | LIEBER, SARAH BETH | reporter.nih.gov |
| Elucidating Social Determinants and Mental Health Needs to Achieve Equity in Rheumatic Disease Care | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $358,000 | September 18, 2023 | August 31, 2025 | COSTENBADER, KAREN H | reporter.nih.gov |
| The Role of MicroRNA-146a in B Cell Function and Autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $354,240 | March 15, 2018 | February 29, 2024 | KING, JENNIFER K | reporter.nih.gov |
| Perivascular adipose tissue in the pathogenesis of lupus vasculopathy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $354,240 | February 1, 2024 | January 31, 2029 | SHI, HONG | reporter.nih.gov |
| Deconstructing Disparities in Lupus Pregnancies | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $352,080 | July 1, 2024 | June 30, 2029 | MEHTA, BELLA | reporter.nih.gov |
| Enhanced diagnostic assessment in lupus using differential scanning calorimetry | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $347,665 | May 5, 2017 | April 30, 2023 | GARBETT, NICHOLA C. | reporter.nih.gov |
| Negative regulation of Lupus by the VISTA Pathway | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $342,271 | February 10, 2017 | December 31, 2021 | NOELLE, RANDOLPH J. | reporter.nih.gov |
| Diagnostic utility of antibodies to post-translationally modified nucleosomes in lupus nephritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $333,193 | August 11, 2023 | July 31, 2025 | MOHAN, CHANDRA | reporter.nih.gov |
| Biochemical Determinants of Chemokine Receptor Signaling | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $331,543 | July 1, 2024 | June 30, 2029 | SMITH, JEFFREY SCOTT | reporter.nih.gov |
| Oxidative Stress and Autoimmunity | NIH | National Institute of Environmental Health Sciences | 2021 | $329,829 | December 1, 2007 | March 31, 2024 | KHAN, M. FIROZE | reporter.nih.gov |
| Using Bioinformatics Methodologies to Explore the Role of Short Interspersed Elements in the Pathogenesis of Idiopathic Inflammatory Myopathies | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $329,616 | April 1, 2024 | March 31, 2029 | NAJJAR, RAYAN | reporter.nih.gov |
| Using the electronic health record to risk-stratify patients with systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $326,270 | May 4, 2018 | April 30, 2023 | BARNADO, APRIL LYNN | reporter.nih.gov |
| Direct-to-family pharmacokinetics intervention for hydroxychloroquine non-adherence in adolescents with systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $317,304 | September 1, 2024 | August 31, 2029 | RANDELL, RACHEL LEIGH | reporter.nih.gov |
| Novel Therapeutic for SLE | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $314,363 | August 1, 2025 | January 31, 2026 | LEBER, ANDREW | reporter.nih.gov |
| Mitochondrial DNA Stress Activation of Interferon Signaling and Lupus Pathology | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $311,228 | March 1, 2017 | May 31, 2022 | SHADEL, GERALD | reporter.nih.gov |
| K24 Advancing Reproductive Rheumatology | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $308,111 | July 20, 2024 | June 30, 2029 | CLOWSE, MEGAN E.B. | reporter.nih.gov |
| Neuroimmune Mechanisms Involved in the Pathogenesis of Hypertension and Renal Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $307,800 | January 1, 2018 | December 31, 2023 | MATHIS, KEISA WILLIAMS | reporter.nih.gov |
| Integrin-Targeted Novel Oral Therapeutics for Lupus Nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $306,500 | August 1, 2023 | July 31, 2024 | LOPEZ, DARLAH MICHELLE | reporter.nih.gov |
| Novel Immunoregulatory Therapeutics for Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $300,000 | January 1, 2021 | June 30, 2022 | LEBER, ANDREW | reporter.nih.gov |
| Anti-inflammatory Activity of a Systemic STING Inhibitory Non-Nucleotide | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $300,000 | December 17, 2021 | April 30, 2024 | BARBER, GLEN N | reporter.nih.gov |
| Nanoimmunotherapy for chronic immune-mediated diseases | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $300,000 | July 14, 2022 | June 30, 2023 | HORWITZ, DAVID A | reporter.nih.gov |
| Functions of LynA and LynB kinases in dendritic-cell pro-inflammatory signaling and lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $300,000 | September 20, 2024 | August 31, 2025 | FREEDMAN, TANYA S. | reporter.nih.gov |
| Kallikrein-kinin system and regulation of lupus autoimmunity: pathways from periphery to brain | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $300,000 | September 3, 2025 | August 31, 2026 | SRIRAM, UMA | reporter.nih.gov |
| FcgR-activated neutrophil regulation of T cells in nephritis and vasculitis | NIH | National Heart, Lung, and Blood Institute | 2025 | $300,000 | September 10, 2025 | August 31, 2026 | MAYADAS, TANYA N | reporter.nih.gov |
| Allogeneic BAFF Ligand Based CAR T-Cells as a Novel Therapy for Systemic Lupus Erythematous | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $299,770 | August 1, 2023 | July 31, 2025 | GIBBONS, HUNTER RAMSDELL | reporter.nih.gov |
| Novel therapeutic target to combat cutaneous lupus | NIH | National Center for Advancing Translational Sciences | 2021 | $298,132 | April 1, 2021 | March 31, 2023 | ASTRUC DIAZ, FANNY | reporter.nih.gov |
| Addressing Social Determinants of Health in Systemic Lupus Erythematosus | NIH | National Institute on Minority Health and Health Disparities | 2024 | $295,924 | September 22, 2024 | August 31, 2025 | YAO, LIXIA | reporter.nih.gov |
| Development of an endocannabinoid microparticle formulation for the topical treatment of cutaneous manifestations of lupus erythematosus. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $293,749 | June 1, 2023 | May 31, 2025 | DRAGANSKI, ANDREW R | reporter.nih.gov |
| Glycan biomarker panels in liquid biopsies for predicting treatment response in lupus nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $275,397 | September 15, 2023 | August 31, 2024 | CASTELLINO, STEPHEN | reporter.nih.gov |
| Development of a novel technology for the determination of a physiologic phenotype in patients with Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $272,392 | September 22, 2022 | February 29, 2024 | JACKSON, KEVIN | reporter.nih.gov |
| Role of Two Interferon Regulatory Genes in Lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $262,200 | March 1, 2020 | February 28, 2023 | NATH, SWAPAN K. | reporter.nih.gov |
| Development of specific peptide reagents for serologic monitoring of Exostosin autoantibodies in membranous lupus nephritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $259,379 | September 5, 2022 | February 29, 2024 | LARSEN, CHRISTOPHER P | reporter.nih.gov |
| Altered protein structures and neoepitopes in lupus neutrophils from dysregulated splicing of messenger RNA | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $256,808 | March 21, 2025 | February 28, 2027 | MUSTELIN, TOMAS M | reporter.nih.gov |
| PNP deficiency and cytosolic DNA in lupus pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $254,250 | September 24, 2021 | January 25, 2022 | NIEWOLD, TIMOTHY B | reporter.nih.gov |
| Novel Nontoxic Therapeutic Interventions for Autoimmune Inflammatory Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $251,250 | May 1, 2014 | April 30, 2024 | ARANOW, CYNTHIA | reporter.nih.gov |
| "Lnc"ing XIST Ribonucleoprotein Particles to Female Sex-Attributed Biases in Autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $249,000 | September 21, 2022 | May 31, 2028 | DOU, DIANA REMY | reporter.nih.gov |
| IgG glycosylation in lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $244,600 | July 18, 2022 | June 30, 2024 | BHARGAVA, RHEA | reporter.nih.gov |
| Loss of Intrinsic Control in Autoimmune T Helper Cells with Signaling Variants | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $242,350 | March 1, 2014 | May 31, 2022 | ROOSE, JEROEN | reporter.nih.gov |
| Early and Personalized Cardiovascular Disease Preventive Care in Lupus Nephritis (EPiC-LN) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $238,944 | August 20, 2024 | January 31, 2026 | GARG, SHIVANI | reporter.nih.gov |
| Trispecific Killer Cell Engager for the Treatment of Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $235,500 | April 9, 2025 | March 31, 2027 | HATEFI, ARASH | reporter.nih.gov |
| University of Michigan Clinical Autoimmunity Center of Excellence | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $234,000 | May 1, 2019 | April 30, 2024 | KHANNA, DINESH | reporter.nih.gov |
| Axl receptor tyrosine kinase, a potential therapeutic target in glomerulonephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $233,684 | April 1, 2019 | March 31, 2022 | SHAO, WEN-HAI | reporter.nih.gov |
| Circadian dysregulation of immune function in SLE | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $226,529 | July 1, 2020 | June 30, 2022 | DAVIDSON, ANNE | reporter.nih.gov |
| IgA-containing immune complexes in plasmacytoid dendritic cell activation in SLE | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $217,625 | May 22, 2020 | April 30, 2022 | HAMERMAN, JESSICA A | reporter.nih.gov |
| The Mechanism of Hematological Abnormalities in Systemic Autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $216,113 | May 1, 2025 | September 30, 2025 | REIZIS, BORIS | reporter.nih.gov |
| Understanding the immunometabolic mechanism of VGLL3 mediating female-biased autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $216,098 | April 1, 2022 | December 31, 2022 | LIANG, YUN | reporter.nih.gov |
| Plasma cell differentiation of autoreactive B cells is governed by TLR9 dependent metabolic reprogramming | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $214,467 | August 10, 2020 | July 31, 2023 | NÜNDEL, KERSTIN | reporter.nih.gov |
| Mentoring the next generation of researchers in pediatric autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $212,574 | January 20, 2025 | December 31, 2029 | JACKSON, SHAUN WILLIAM | reporter.nih.gov |
| "Lnc"ing XIST Ribonucleoprotein Particles to Female Sex-Attributed Biases in Autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $211,276 | September 21, 2022 | February 28, 2025 | DOU, DIANA REMY | reporter.nih.gov |
| FRET based imaging of cyclic dinucleotide dynamics in living systems | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $207,241 | July 1, 2020 | June 30, 2023 | WOODWARD, JOSHUA | reporter.nih.gov |
| Burden, correlates, and outcomes of poor cognitive and physical functioning in the lupus population | NIH | National Institute on Aging | 2024 | $205,735 | February 15, 2019 | November 30, 2025 | PLANTINGA, LAURA | reporter.nih.gov |
| Systemic travel of damaged DNA in photosensitive autoimmune disorders | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $204,798 | August 1, 2024 | June 30, 2026 | CARPENTER, MAE ALEXANDRA | reporter.nih.gov |
| Genetics of organ-specific lupus disease sequelae | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $204,762 | July 22, 2020 | June 30, 2023 | WAGGONER, STEPHEN N. | reporter.nih.gov |
| Autoimmunity to LINE-1-encoded antigens in SLE pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $204,688 | February 7, 2020 | January 31, 2023 | ANDRADE, FELIPE | reporter.nih.gov |
| alpha v integrin regulation of B cell tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $200,000 | December 16, 2020 | November 30, 2021 | LACY-HULBERT, ADAM | reporter.nih.gov |
| Computational methods using electronic health records and registry data to detect and predict clinical outcomes in rheumatic disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $197,001 | April 10, 2019 | March 4, 2022 | GIANFRANCESCO, MILENA ANNE | reporter.nih.gov |
| Tpl2 regulation of pDC function and SLE pathogenesis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $193,340 | August 19, 2020 | June 30, 2023 | WATFORD, WENDY T | reporter.nih.gov |
| Mapping the genes that predispose to murine lupus | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $190,621 | February 1, 2020 | January 31, 2024 | VIA, CHARLES S. | reporter.nih.gov |
| Cellular mechanisms of macrophage activation syndrome | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $188,772 | June 17, 2025 | May 31, 2030 | CANNY, SUSAN PRISCILLA | reporter.nih.gov |
| Identification of novel Inhibitory receptors Involved In B cell tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $187,555 | June 9, 2020 | May 31, 2023 | GETAHUN, ANDREW | reporter.nih.gov |
| Canonical and non-canonical vitamin D activation pathways in systemic lupus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $185,625 | September 1, 2020 | August 31, 2023 | RAMAN, CHANDER | reporter.nih.gov |
| Adverse pregnancy outcomes in women with systemic lupus erythematosus: improving and validating risk prediction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $185,269 | September 1, 2020 | August 31, 2023 | SALMON, JANE E | reporter.nih.gov |
| Regulation of lupus pathogenesis through modulation of thymic development of pathobiont-specific T cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $183,816 | July 15, 2022 | September 30, 2023 | ZEGARRA RUIZ, DANIEL FERNANDO | reporter.nih.gov |
| Avoidable Acute Care Use among Patients with Lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $178,195 | March 5, 2017 | February 28, 2022 | FELDMAN, CANDACE HILLARY | reporter.nih.gov |
| TNF-alpha Blockade with Certolizumab to Prevent Pregnancy Complications in High-Risk Patients with APS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $174,810 | August 15, 2016 | June 30, 2023 | SALMON, JANE E | reporter.nih.gov |
| The Role of VGLL3 in Sexually Dimorphic Interferon-Driven Inflammation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $174,244 | April 1, 2018 | December 31, 2022 | LIANG, YUN | reporter.nih.gov |
| Chemoproteomic-Enabled Strategy to Study SLC Transporter Roles in Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $172,435 | July 1, 2021 | January 2, 2022 | PARKER, CHRISTOPHER G | reporter.nih.gov |
| Immune Dysregulation in Pediatric SLE Pathogenesis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $169,304 | May 7, 2017 | December 31, 2022 | HSIEH, WEN-YUAN E | reporter.nih.gov |
| TNF deficiency induces breach of B cell tolerance via altering B cell regulatory signals | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $167,500 | June 16, 2021 | May 31, 2023 | QUACH, TAM D | reporter.nih.gov |
| Establishing a model of recurrent/chronic urinary tract infection in lupus-prone mice | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $167,500 | November 18, 2022 | October 31, 2024 | GALLUCCI, STEFANIA | reporter.nih.gov |
| Implications for Speckled proteins 110 and 140 in adaptive immunity | NIH | National Center for Advancing Translational Sciences | 2023 | $167,500 | August 1, 2023 | July 31, 2024 | BARNES, BETSY J | reporter.nih.gov |
| Mechanisms underlying inflammation-induced alloimmunization to RBC antigens in lupus | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $167,000 | August 1, 2021 | July 31, 2023 | GIBB, DAVID R | reporter.nih.gov |
| Glucagon-like peptide-1 receptor agonists in lupus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $165,000 | September 15, 2025 | July 31, 2027 | JORGE, APRIL | reporter.nih.gov |
| Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $163,026 | August 1, 2025 | July 31, 2030 | ARDALAN, KAVEH | reporter.nih.gov |
| 3D Chromatin Studies in Pediatric B Cells To Study the Genetics of Autoimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $159,500 | November 1, 2021 | October 31, 2024 | JARVIS, JAMES N | reporter.nih.gov |
| A Role of Isolevuglandin Adducts in Essential Hypertension and Systemic Lupus Erythematosus | NIH | National Heart, Lung, and Blood Institute | 2021 | $158,436 | August 1, 2020 | September 30, 2021 | PATRICK, DAVID | reporter.nih.gov |
| Unraveling the contribution of gut microbiome in trichloroethene-mediated autoimmunity | NIH | National Institute of Environmental Health Sciences | 2023 | $158,157 | September 22, 2023 | August 31, 2025 | KHAN, M. FIROZE | reporter.nih.gov |
| Development of antagonists targeting STING in systemic lupus erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $155,628 | January 1, 2020 | December 31, 2021 | GUIDA, WAYNE | reporter.nih.gov |
| Targeting BCMA+ Cells with RNA-engineered CAR T cells to treat Lupus: A Phase 2 clinical study | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $149,008 | August 14, 2024 | January 31, 2026 | JEWELL, CHRISTOPHER M | reporter.nih.gov |
| A Novel Long Noncoding RNA Associated with Systemic Lupus Erythematosus Pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $143,420 | July 1, 2022 | March 13, 2025 | TIAN, RUXIAO | reporter.nih.gov |
| Pinpointing how single-cell states affect genetic regulation of HLA expression in autoimmune diseases | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $142,934 | July 1, 2022 | May 9, 2025 | KANG, JOYCE BLOSSOM | reporter.nih.gov |
| Identifying the Xist interactome during dynamic X inactivation in healthy and lupus-derived B cells | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $136,192 | July 1, 2020 | June 30, 2023 | PYFROM, SARAH CATHERINE | reporter.nih.gov |
| Global and Local Genetic Ancestry Impacts on Differential Outcome of Systemic Lupus Erythematosus and Multiple Sclerosis | NIH | National Institute on Minority Health and Health Disparities | 2021 to 2023 | $129,976 | September 1, 2021 | August 31, 2024 | SOLOMON, OLIVIA | reporter.nih.gov |
| Follicular helper T cells as drivers of epitope spreading | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $125,164 | September 1, 2021 | June 30, 2024 | AKAMA-GARREN, ELLIOT HIDEKI | reporter.nih.gov |
| Computational mapping of human B cell migration and differentiation pathways | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $123,846 | August 19, 2022 | July 31, 2023 | HOEHN, KENNETH | reporter.nih.gov |
| The impact of hydroxychloroquine use on thrombosis and mortality in lupus-related end stage renal disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $121,434 | July 1, 2017 | February 1, 2022 | BRODER, ANNA | reporter.nih.gov |
| Early Life Stress Promotes an Inflammatory Phenotype Leading to Vascular Impairment and Lupus Nephritis Severity | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $116,465 | August 22, 2022 | August 21, 2025 | KELLUM, CAILIN | reporter.nih.gov |
| Defining the Role of Dynamic X Chromosome Inactivation in Age-Associated B Cells for Female-Biased Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $108,820 | July 1, 2023 | June 30, 2026 | LOVELL, CLAUDIA DARNELL | reporter.nih.gov |
| Rab4A Control of Liver Dysfunction in Mouse Models of Systemic Lupus Erythematosus. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $104,446 | July 1, 2022 | June 30, 2024 | PATEL, AKSHAY | reporter.nih.gov |
| Immune system dysfunction and gut dysbiosis in the pathogenesis of vascular dysfunction in autoimmunity | NIH | National Heart, Lung, and Blood Institute | 2021 | $101,529 | January 1, 2020 | December 31, 2021 | TAYLOR, ERIN BASSFORD | reporter.nih.gov |
| A Novel Inflammatory Dendritic Cell in Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $100,000 | September 20, 2021 | August 31, 2023 | GANESAN, LATHA PRABHA | reporter.nih.gov |
| Superwoman Coping: A multi-level analysis of self-management behaviors and cardiovascular disease risk among Black women with systemic lupus erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $98,512 | June 1, 2024 | May 31, 2027 | LEUNG, JERIK | reporter.nih.gov |
| The Roles and Regulation of TLR7 in Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $92,788 | August 1, 2020 | July 31, 2023 | COSGROVE, HAYLEE | reporter.nih.gov |
| CpG-B ODN Mediated Protection from Systemic Lupus Erythematosus | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $88,987 | July 25, 2024 | July 24, 2028 | OAKLAND, DAVID NOAH | reporter.nih.gov |
| The Role of an MSH6 Gene Variant and UV Radiation in Systemic Lupus Erythematosus | NIH | National Institute of Environmental Health Sciences | 2021 | $87,463 | August 12, 2020 | July 31, 2022 | MEAS, RITHY | reporter.nih.gov |
| Investigating the Role of Care Retention in Lupus Disease Outcomes and Disparities in Young Adult and Pediatric Patients | NIH | National Institute on Minority Health and Health Disparities | 2021 to 2022 | $83,330 | September 26, 2020 | August 31, 2023 | SCHLETZBAUM BOWLER, MARIA ANNA | reporter.nih.gov |
| Early-Stage Autoimmunity in Sjögren's Disease and Systemic Lupus Erythematosus | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $74,267 | August 1, 2024 | July 31, 2028 | WOOD, REBECCA ADEN | reporter.nih.gov |
| Determining the role of type I interferons in ultraviolet-B light induced keratinocyte death | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $71,002 | August 1, 2020 | April 30, 2023 | LOFTUS, SHANNON | reporter.nih.gov |
| Early Access to Kidney Transplantation among Patients with Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $70,773 | April 1, 2023 | May 31, 2024 | MCPHERSON, LAURA | reporter.nih.gov |
| Genetic regulation of genes on active and inactive X chromosome and their contribution to sex-biased diseases | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $69,421 | September 1, 2023 | August 31, 2025 | MARKUS, HAVELL | reporter.nih.gov |
| A new therapeutic approach against kidney damage in LN and COVID-19 | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $69,174 | March 4, 2022 | April 28, 2023 | VILLANUEVA, VERONICA | reporter.nih.gov |
| The Role of VGLL3 in Sexually Dimorphic Interferon-Driven Inflammation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $62,640 | March 10, 2023 | November 30, 2023 | LIANG, YUN | reporter.nih.gov |
| SLE-AWARE: SLE-- A Window into APOL1 Regulation and Expression | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $62,049 | September 20, 2021 | January 24, 2022 | BLAZER, ASHIRA DESHON | reporter.nih.gov |
| Using Glycomic Signatures to Monitor Disease Progression and Predict Treatment Response in Lupus Nephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $54,147 | July 2, 2025 | July 1, 2027 | ANGERSTEIN, AARON | reporter.nih.gov |
| Influence of DNA methylation changes on gene expression from the inactive X chromosome in B cells | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $49,538 | August 1, 2025 | July 31, 2028 | WELTER, EMMA MALEY | reporter.nih.gov |
| Cardiovascular Risks Associated with Pregnancy in African American Women with Systemic Lupus Erythematosus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $26,712 | September 1, 2020 | December 31, 2021 | ANGLEY, MEGHAN | reporter.nih.gov |
| ANRF 2025 Research Symposium | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $18,000 | November 15, 2024 | November 14, 2025 | DOUGLAS, LAURA | reporter.nih.gov |
| Omega-3 Fatty Acid Suppression of Silica-induced Inflammasome Activation in a Novel Alveolar Macrophage Model | NIH | National Institute of Environmental Health Sciences | 2021 | $17,423 | May 16, 2019 | August 30, 2021 | WIERENGA, KATHRYN ALEXANDRIA | reporter.nih.gov |
| IgG glycosylation in lupus nephritis | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $7,533 | July 18, 2022 | July 19, 2022 | BHARGAVA, RHEA | reporter.nih.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 170 | $110,622,510 | 0 | $0 |
| 2024 | 184 | $106,303,949 | 0 | $0 |
| 2023 | 191 | $104,606,522 | 0 | $0 |
| 2022 | 199 | $98,379,676 | 0 | $0 |
| 2021 | 194 | $121,301,519 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
| Open opportunity | Number | Agency | Listing | Closes | Award ceiling | Why it matches |
|---|---|---|---|---|---|---|
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) | PA-24-188 | NIH | May 7, 2027 | Not listed | Notice number printed on 1 award here | |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) | PA-24-184 | NIH | May 8, 2027 | Not listed | Notice number printed on 1 award here | |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) | PA-24-182 | NIH | May 8, 2027 | Not listed | Notice number printed on 1 award here | |
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) | PA-24-254 | NIH | July 12, 2027 | Not listed | Notice number printed on 1 award here | |
| Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required) | RFA-AI-27-002 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required) | RFA-AI-27-005 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) | PAR-25-370 | NIH | 93.855 | November 16, 2026 | $50,000 | Same assistance listing 93.855 as 191 awards here |
| Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) | PAR-25-369 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) | PAR-25-371 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) | PAR-25-379 | NIH | 93.855 | January 7, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| HIV/AIDS Clinical Trials Network Leadership and Operations Centers | RFA-AI-28-001 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| HIV/AIDS Clinical Trials Network Laboratory Centers | RFA-AI-28-002 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| HIV/AIDS Clinical Trials Network Statistical and Data Management Centers | RFA-AI-28-003 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| HIV/AIDS Clinical Trials Network Clinical Trials Units | RFA-AI-28-004 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases | RFA-AI-28-014 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Immune Tolerance Network (UM1 Clinical Trial Required) | RFA-AI-28-005 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed) | RFA-AI-28-012 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed) | RFA-AI-28-024 | NIH | 93.855 | February 11, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
| NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed) | RFA-LM-28-001 | NIH | 93.855 | February 11, 2027 | $775,000 | Same assistance listing 93.855 as 191 awards here |
| NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) | PA-27-100 | NIH | 93.855 | April 5, 2027 | Not listed | Same assistance listing 93.855 as 191 awards here |
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.