Data / Research funding / Inflammatory Bowel Disease
Inflammatory Bowel Disease: 792 NIH awards ($821.8M) to 188 organizations
792 NIH awards ($821.8M) in the NIH spending category Inflammatory Bowel Disease, to 188 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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The 500 largest of 792 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Functional Microbiomics, Inflammation and Pathogenicity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $12,492,994 | March 1, 2018 | February 29, 2028 | LAMONT, RICHARD J | reporter.nih.gov |
| Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed with Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $8,401,766 | April 1, 2023 | March 31, 2028 | HYAMS, JEFFREY SAMUEL | reporter.nih.gov |
| Precision IBD via genetics and genomics: integrating International and multi-omic datasets, expanding studies in diverse populations, and defining mechanisms of unmet clinical needs in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $7,890,535 | September 30, 2002 | June 30, 2027 | CHO, JUDY H. | reporter.nih.gov |
| Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $7,269,328 | March 15, 2023 | February 29, 2028 | DULAI, PARAMBIR SINGH | reporter.nih.gov |
| Identifying Immune and Epithelial Network Signatures in Very Early Onset Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $7,187,152 | September 15, 2020 | June 30, 2026 | SNAPPER, SCOTT B | reporter.nih.gov |
| The Cleveland Digestive Diseases Research Core Center (DDRCC) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $6,425,666 | February 15, 2015 | August 31, 2030 | COMINELLI, FABIO | reporter.nih.gov |
| Host and microbial basis of human ulcerative colitis and pouchitis: Identification, role, mechanisms, and resource development of host susceptibility and pathobiont factors | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $6,122,586 | September 1, 2019 | May 31, 2025 | CHANG, EUGENE B | reporter.nih.gov |
| Spatial and temporal resolution to dissect cellular circuits controlling intestinal physiology, immunity, and inflammatory pathologies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $5,934,972 | August 1, 2023 | May 31, 2028 | XAVIER, RAMNIK J | reporter.nih.gov |
| Identifying Microbial, Epithelial and Immune Cell Interactions that Mediate Mucosal Homeostasis and Determine IBD Phenotypes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $5,810,225 | September 19, 2013 | June 30, 2025 | SARTOR, RYAN B | reporter.nih.gov |
| Determinants of inception of inflammation in inflammatory bowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $5,397,834 | August 24, 2021 | May 31, 2027 | ANANTHAKRISHNAN, ASHWIN N | reporter.nih.gov |
| Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer | NIH | National Cancer Institute | 2021 to 2025 | $5,241,422 | July 21, 2020 | June 30, 2027 | KANNEGANTI, THIRUMALA-DEVI | reporter.nih.gov |
| Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $5,235,383 | September 18, 2019 | June 30, 2025 | WANG, DAVID | reporter.nih.gov |
| Utility of Random Biopsies in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $5,031,513 | July 1, 2024 | June 30, 2029 | LEWIS, JAMES D | reporter.nih.gov |
| Intracellular Innate Immune Receptors in Cancer Suppression and Immunotherapy | NIH | National Cancer Institute | 2021 to 2025 | $4,541,273 | September 17, 2019 | August 31, 2026 | TING, JENNY P | reporter.nih.gov |
| Cytokine regulation of mucosal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,234,402 | June 6, 2019 | June 30, 2029 | SONNENBERG, GREGORY F | reporter.nih.gov |
| Is Obesity an Infectious Disease?: Gut bacterial and fungal translocation as an underappreciated driver of visceral adipose expansion. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,971,090 | September 30, 2021 | June 30, 2026 | DEVKOTA, SUZANNE | reporter.nih.gov |
| Molecular basis of bioelectronic medicine | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,937,630 | May 1, 2016 | April 30, 2027 | TRACEY, KEVIN J | reporter.nih.gov |
| Mechanisms and pathophysiologic impact of claudin-2 modulation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,845,865 | September 29, 2001 | June 30, 2028 | TURNER, JERROLD R. | reporter.nih.gov |
| Mechanisms associated with flares and remission in colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,593,722 | May 1, 2017 | May 31, 2026 | LIRA, SERGIO A. | reporter.nih.gov |
| Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported Outcomes | NIH | National Center for Advancing Translational Sciences | 2021 to 2023 | $3,537,149 | April 20, 2020 | March 31, 2025 | SANDS, BRUCE E | reporter.nih.gov |
| Characterization of Mucosal Lymphocytes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,410,819 | September 30, 1992 | June 30, 2029 | BLUMBERG, RICHARD S | reporter.nih.gov |
| Integration of genomics and transcriptomics to investigate biological pathways in very early onset IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,353,628 | July 1, 2021 | April 30, 2027 | KELSEN, JUDITH RACHEL | reporter.nih.gov |
| The PAS Sensor Family and Human Health | NIH | National Institute of Environmental Health Sciences | 2021 to 2024 | $3,342,660 | September 15, 2017 | May 31, 2026 | BRADFIELD, CHRISTOPHER A | reporter.nih.gov |
| Periodontitis Role in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $3,340,009 | September 1, 2025 | August 31, 2029 | THUMBIGERE-MATH, VIVEK | reporter.nih.gov |
| The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,299,380 | March 4, 2019 | February 28, 2027 | FAITH, JEREMIAH JAMES | reporter.nih.gov |
| Functional outcomes of inflammatory bowel disease associated variants | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,272,687 | September 18, 2013 | May 31, 2028 | ABRAHAM, CLARA | reporter.nih.gov |
| Microbiota-immune interactions that promote intestinal homeostasis | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,111,145 | June 15, 2021 | May 31, 2026 | ROUND, JUNE LOUISE | reporter.nih.gov |
| Mechanism of action for the epithelial-specific ER stress sensor IRE1β in regulating intestinal homeostasis and host defense | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $3,050,147 | September 1, 1993 | March 31, 2026 | LENCER, WAYNE I | reporter.nih.gov |
| Dissecting the pathogenesis and outcomes of PSC using multi-omics by studying the exposome and genome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $3,027,125 | September 1, 2018 | July 31, 2025 | LAZARIDIS, KONSTANTINOS N | reporter.nih.gov |
| Development of TP-317 in Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,996,955 | September 18, 2017 | February 28, 2027 | PARKINSON, JOHN | reporter.nih.gov |
| Neuregulin-4: A Novel Therapy for Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $2,942,139 | September 20, 2016 | June 30, 2024 | GHOSH, SOUMITRA | reporter.nih.gov |
| Regulation and function of mucosal IgA immune responses to mycobiota in the gut. | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,924,410 | June 1, 2021 | May 31, 2027 | ILIEV, ILIYAN DIMITROV | reporter.nih.gov |
| Therapeutic targeting of protein interactions to reverse MLCK1-mediated intestinal barrier loss and ameliorate disease. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,917,818 | July 1, 2005 | June 30, 2029 | TURNER, JERROLD R. | reporter.nih.gov |
| Mechanisms of mucosal autoinflammation elucidated by a novel monogenic transcription factor defect | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,902,111 | April 15, 2021 | March 31, 2026 | LUCAS, CARRIE L. | reporter.nih.gov |
| Role of CREM in Amebic Colitis and Inflammatory Bowel Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,896,698 | August 1, 1989 | December 31, 2027 | PETRI, WILLIAM A | reporter.nih.gov |
| Dietary fat-activated colonocyte-macrophage ketone shuttle drives intestinal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $2,893,480 | July 18, 2025 | June 30, 2029 | RUAN, HAI-BIN | reporter.nih.gov |
| Genetic regulation of epithlial injury in ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,842,245 | September 22, 2025 | September 21, 2029 | KATTAH, MICHAEL GEORGE | reporter.nih.gov |
| Intestinal Inflammation: Signaling proteins and the rate of PMN transmigration | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,831,952 | October 1, 2002 | April 30, 2027 | PARKOS, CHARLES A | reporter.nih.gov |
| Absorption of vitamin B1 along the intestinal tract: Physiology, pathophysiology and cell biology aspects | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,831,663 | August 1, 1999 | December 31, 2025 | SAID, HAMID M | reporter.nih.gov |
| Precise Infliximab Exposure and Pharmacodynamic Control to Achieve Deep Remission in Pediatric Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,803,917 | June 1, 2022 | March 31, 2027 | MINAR, PHILLIP P | reporter.nih.gov |
| Bacterial metabolites controlling Th17 and Treg cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,799,466 | September 1, 2016 | July 31, 2025 | HUH, JUN R. | reporter.nih.gov |
| Structure-Guided Design of Intestine-Selective AHR Agonists for Restoration of Gut Barrier Integrity in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,795,439 | June 1, 2022 | March 31, 2027 | CHAIKOF, ELLIOT | reporter.nih.gov |
| Treating colon cancer by regulating intestinal immunity through microbial metabolism | NIH | National Cancer Institute | 2021 to 2025 | $2,772,249 | June 1, 2021 | May 31, 2027 | ARPAIA, NICHOLAS | reporter.nih.gov |
| Supramolecular biomaterials for tuning the inflammatory properties of the complement system | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,759,425 | June 1, 2022 | May 31, 2027 | COLLIER, JOEL H | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,751,010 | September 23, 2021 | August 31, 2026 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Identification and characterization of inflammatory bowel disease causal variants | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,724,317 | August 15, 2022 | June 30, 2027 | HUANG, HAILIANG | reporter.nih.gov |
| Dietary Regulation of Intestinal Inflammation and Repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,700,479 | March 15, 2022 | January 31, 2027 | ARTIS, DAVID | reporter.nih.gov |
| Regulation of neutrophil plasticity, heterogenicity, and functional ambivalency by WNT5 in colitis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $2,685,326 | July 7, 2025 | June 30, 2029 | WU, DIANQING | reporter.nih.gov |
| Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,674,708 | March 31, 2021 | February 28, 2026 | WILSON, KEITH T. | reporter.nih.gov |
| The Role of Crypt Fissioning in IBD Ulcer Healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,649,727 | February 24, 2021 | January 31, 2026 | BARRETT, TERRENCE A. | reporter.nih.gov |
| Gut bacterial metallophores in the development and severity of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,638,713 | April 1, 2022 | February 28, 2027 | SAMUELSON, DERRICK R | reporter.nih.gov |
| Role of epithelial ROS signaling in mediating psychological stress-induced mucosal dysfunction and colitis predisposition | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,622,833 | July 31, 2022 | May 31, 2027 | ALLEN, JACOB MATTHEW | reporter.nih.gov |
| Mechanisms of telomere-induced disease: Role of intestinal malabsorption, barrier dysfunction and dsybiosis. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,617,623 | June 1, 2022 | March 31, 2027 | SAHIN, ERGUN | reporter.nih.gov |
| Role of the environmental sensor, AhR on colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,615,887 | September 27, 2021 | August 31, 2027 | NAGARKATTI, PRAKASH S | reporter.nih.gov |
| Determining genomic and host-environment contributions to IBD phenotypes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,592,024 | September 30, 2022 | June 30, 2027 | MCGOVERN, DERMOT PATRICK | reporter.nih.gov |
| Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiota | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,589,752 | March 15, 2021 | July 6, 2026 | LITTMAN, DAN | reporter.nih.gov |
| Intestinal surveillance by intraepithelial lymphocytes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,589,419 | July 1, 2017 | April 30, 2026 | MUCIDA, DANIEL S | reporter.nih.gov |
| Dietary fiber and soy protein-based microbiome metabolites for IBD prevention | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,557,667 | July 3, 2018 | December 31, 2026 | MARTENS, ERIC C | reporter.nih.gov |
| Neuronal and molecular mechanisms underlying neural regulation of innate immunity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,524,273 | September 12, 2017 | August 31, 2027 | SUN, JINGRU | reporter.nih.gov |
| Neuro-immune regulation of intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,522,331 | September 17, 2020 | July 31, 2025 | ARTIS, DAVID | reporter.nih.gov |
| Targeting the Mycobiome in Genetically Defined Patients with Crohns Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,513,409 | May 1, 2021 | February 28, 2026 | UNDERHILL, DAVID M. | reporter.nih.gov |
| Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel Disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,512,710 | July 12, 2018 | June 30, 2027 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Mechanisms of Gastrointestinal COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,503,469 | July 15, 2022 | June 30, 2027 | CIORBA, MATTHEW AARON | reporter.nih.gov |
| Continuation Application for the development of Integrated continuous and single-use (ICS) bioproduction platform (Phase IIB) | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $2,495,306 | January 1, 2016 | March 31, 2024 | SHINKAZH, OLEG | reporter.nih.gov |
| Bidirectional Brain-Gut interactions, chronic neuroinflammation and neurodegeneration after traumatic brain injury | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,480,051 | August 15, 2022 | July 31, 2027 | FADEN, ALAN IRA | reporter.nih.gov |
| Structure, function, and modulation of claudin cation channels in the GI tract | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,456,433 | September 30, 2021 | July 31, 2027 | WEBER, CHRISTOPHER | reporter.nih.gov |
| Photoresponsive materials to study matricellular signaling dynamics during crypt formation and fission | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,423,541 | August 1, 2019 | April 30, 2028 | ANSETH, KRISTI S. | reporter.nih.gov |
| Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,422,875 | February 1, 2021 | January 31, 2026 | MARTH, JAMEY | reporter.nih.gov |
| Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,421,990 | September 1, 2021 | July 31, 2026 | CERVANTES BARRAGAN, LUISA | reporter.nih.gov |
| Tuft cell heterogeneity in function, lineage, and structure in ileal inflammatory disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,405,842 | February 15, 2016 | January 31, 2026 | LAU, KEN S | reporter.nih.gov |
| Molecular Pathways Regulating Tissue-resident Memory T cells in the Gut | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,397,988 | March 1, 2022 | February 28, 2027 | DOUGAN, MICHAEL LAWRENCE | reporter.nih.gov |
| Decode Mitochondrial Morphology Dynamics to Predict Cell Fate Decisions | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,379,500 | September 8, 2022 | August 31, 2027 | SCHOENEBERG, JOHANNES | reporter.nih.gov |
| Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,378,553 | January 1, 2021 | December 31, 2026 | AHERN, PHILIP PATRICK | reporter.nih.gov |
| Control of Neutrophilic Inflammation in Intestinal Health and Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,362,552 | September 1, 2016 | July 31, 2025 | MCCORMICK, BETH A | reporter.nih.gov |
| Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,355,463 | September 30, 2002 | June 30, 2027 | CHO, JUDY H. | reporter.nih.gov |
| Targeting bacterial proteases involved in PAR signaling to treat inflammatory bowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,355,154 | September 21, 2021 | July 31, 2026 | BOGYO, MATTHEW | reporter.nih.gov |
| Impact of symbiotic protists on intestinal T cell homeostasis and inflammation. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,328,152 | March 1, 2021 | February 28, 2026 | HOWITT, MICHAEL R | reporter.nih.gov |
| Gene discoveries in subjects with Crohn's disease of African descent | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,305,204 | March 1, 2011 | June 30, 2025 | KUGATHASAN, SUBRA | reporter.nih.gov |
| Type III interferon Control of Mucosal Immunity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,301,166 | August 1, 2017 | December 31, 2026 | ZANONI, IVAN | reporter.nih.gov |
| Immune Interactions with the Mucus-Associated Microbiota | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,287,659 | July 12, 2021 | June 30, 2027 | MAYNARD, CRAIG L | reporter.nih.gov |
| Characterizing and predicting colitis in immune checkpoint blockade-treated cancer patients | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,286,893 | June 1, 2020 | May 31, 2026 | GNJATIC, SACHA | reporter.nih.gov |
| University of Miami IBD Genetic Research Center: Understanding the Genetic Architecture of IBD in the South Florida community | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,285,492 | September 30, 2022 | June 30, 2027 | MCCAULEY, JACOB L | reporter.nih.gov |
| Development of a high-throughput epigenomic mapping platform to molecularly phenotype Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,282,116 | September 1, 2022 | August 31, 2025 | JOHNSTONE, ANDREA LYNN | reporter.nih.gov |
| Activity Probes to Guide Precision Microbiome Therapy | NIH | National Center for Complementary & Integrative Health | 2024 to 2025 | $2,279,811 | September 1, 2024 | May 31, 2029 | LONGMAN, RANDY S | reporter.nih.gov |
| A Novel Immunological-Directed Live Biotherapy Product for Treating Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,277,236 | July 5, 2022 | July 31, 2025 | FANGER, GARY | reporter.nih.gov |
| Genomics of Inflammatory Bowel Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,275,152 | September 20, 2019 | August 31, 2025 | KOTTYAN, LEAH CLAIRE | reporter.nih.gov |
| Integrative and longitudinal multi-omic risk assessment in inflammatory bowel disease progression | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,272,364 | September 30, 2022 | June 30, 2027 | KUGATHASAN, SUBRA | reporter.nih.gov |
| Exacerbation of Colitis by Enterobacteriaceae | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,260,715 | January 15, 2015 | March 31, 2026 | BAUMLER, ANDREAS J | reporter.nih.gov |
| Bacterial adaptions in host-microbe interactions. | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,240,628 | March 11, 2022 | February 28, 2027 | CHU, HIUTUNG | reporter.nih.gov |
| Estrogen-mediated immune regulation in human and experimental inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,237,890 | March 1, 2021 | February 28, 2026 | GOODMAN, WENDY ANN | reporter.nih.gov |
| Mechanisms that alter lymphatic transport in inflammatory bowel disease | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,237,567 | February 7, 2022 | January 31, 2027 | RANDOLPH, GWENDALYN J | reporter.nih.gov |
| Role of Sam68 in Proinflammatory Signaling | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,234,964 | April 1, 2022 | February 28, 2027 | RAMAKRISHNAN, PARAMESWARAN | reporter.nih.gov |
| Low Dose Interleukin-2 for Regulatory T cell Modulation and the Treatment of Crohnâs Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,232,504 | September 1, 2020 | June 30, 2026 | SNAPPER, SCOTT B | reporter.nih.gov |
| Targeting the eNAMPT/TLR4 pathway to reduce Inflammatory Bowel Disease severity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,219,663 | September 19, 2022 | July 31, 2025 | GARCIA, JOE G. N. | reporter.nih.gov |
| Intestinal single cell analyses and population differences in innate immunity in Crohn's disease drive treatment response and clinical heterogeneity: towards Precision IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,208,042 | February 5, 2020 | January 31, 2025 | CHO, JUDY H. | reporter.nih.gov |
| Montreal-Boston Collaborative GRC | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,199,265 | September 30, 2002 | June 30, 2027 | RIOUX, JOHN D. | reporter.nih.gov |
| Mucosal Macrophages and Tertiary Lymphoid Structures in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,182,924 | September 16, 2016 | February 28, 2027 | BOGUNOVIC, MILENA | reporter.nih.gov |
| Colon O-glycosylated mucus in the homeostasis of microbiota and host | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,177,903 | August 1, 2010 | April 30, 2027 | XIA, LIJUN | reporter.nih.gov |
| Mechanisms Controlling the Development and Function of Intestinal Effector Treg cells | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,167,146 | February 21, 2023 | January 31, 2028 | WEAVER, CASEY T | reporter.nih.gov |
| Novel Function of Native Low-Density Lipoprotein in Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,161,732 | September 21, 2021 | July 31, 2025 | ZAKI, HASAN | reporter.nih.gov |
| Regulation of intestinal epithelial barrier function by intercellular junction proteins in health and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,159,229 | September 24, 2001 | May 31, 2026 | NUSRAT, ASMA | reporter.nih.gov |
| Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,146,203 | May 15, 2023 | February 29, 2028 | DORRESTEIN, PIETER C | reporter.nih.gov |
| Harnessing iron acquisition to hinder enterobacterial pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,144,328 | February 23, 2023 | January 31, 2028 | RAFFATELLU, MANUELA | reporter.nih.gov |
| Mononuclear phagocyte networks in mycobiota regulation and antifungal immunity. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,139,400 | May 1, 2020 | April 30, 2026 | ILIEV, ILIYAN DIMITROV | reporter.nih.gov |
| Metabolic Regulation of Inflammation by Microbial SCFA | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,131,668 | April 1, 2015 | June 30, 2028 | COLGAN, SEAN P | reporter.nih.gov |
| Biomaterials for modulating the gut microbiome for immune activation | NIH | National Cancer Institute | 2022 to 2025 | $2,127,257 | May 1, 2022 | April 30, 2027 | MOON, JAMES J. | reporter.nih.gov |
| Examining Carbon Monoxide to Treat Inflammatory Conditions using Experimental Colitis Models | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,126,619 | June 10, 2019 | June 30, 2025 | WANG, BINGHE | reporter.nih.gov |
| Manganese in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,125,856 | September 24, 2025 | July 31, 2030 | SEO, YOUNG AH | reporter.nih.gov |
| Population-Based Characterization of Metabolic Pathways to Predict Pediatric Crohn's Disease Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,117,645 | July 15, 2022 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Commensal fungal communities in the regulation of immunity and intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,115,146 | July 1, 2017 | April 30, 2027 | ILIEV, ILIYAN DIMITROV | reporter.nih.gov |
| Mechanisms of gasdermin-dependent epithelial function in inflammatory bowel disease. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,109,541 | April 8, 2021 | June 30, 2030 | PIZARRO, THERESA TORRES | reporter.nih.gov |
| Regulation of Mucosal Lymphocytes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,107,939 | September 1, 1998 | March 31, 2028 | BLUMBERG, RICHARD S | reporter.nih.gov |
| Immune interactions with commensal microbes in early life | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,107,374 | November 2, 2022 | October 31, 2027 | HSIEH, CHYI S | reporter.nih.gov |
| Kruppel-like factor-2 CD4+ T cells and intestinal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,084,668 | September 1, 2023 | August 31, 2027 | WAY, SING SING | reporter.nih.gov |
| Folic Acid Supplementation and Colitis-associated Colon Carcinogenesis | NIH | National Cancer Institute | 2022 to 2025 | $2,082,906 | May 11, 2022 | April 30, 2027 | CLAPPER, MARGIE L. | reporter.nih.gov |
| Role of Class IIa HDACs HDAC4 and HDAC7 in Pathogenic Th17 Cell Development and Colitis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,079,060 | February 1, 2022 | January 31, 2027 | CHEUNG, KALUNG | reporter.nih.gov |
| Paneth cell mitochondria and intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,076,999 | September 15, 2025 | September 14, 2029 | THEISS, ARIANNE L | reporter.nih.gov |
| Sex Differences in Statural Growth Impairment in Pediatric Crohn's Disease: Part 2 | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,074,213 | September 11, 2023 | May 31, 2028 | GUPTA, NEERA | reporter.nih.gov |
| Identification and Functional Characterization of Bioactive Microbial Metabolites of Beta-Glucan Degradation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,060,432 | June 15, 2023 | April 30, 2028 | VASU, CHENTHAMARAKSHAN | reporter.nih.gov |
| Novel Oral Yeast Immunotherapies for Ulcerative Colitis (Fast-track) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,057,937 | May 1, 2022 | April 30, 2025 | YANG, ZHIYONG | reporter.nih.gov |
| Assessing biomarkers of intestinal fibrosis and inflammation in Crohn's Disease via an endoscopic imaging catheter | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,046,791 | September 1, 2020 | August 31, 2025 | HIGGINS, PETER D.R. | reporter.nih.gov |
| Identifying Neutrophil Specific Mechanisms for Resistance to Biologics in Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,031,221 | August 1, 2023 | May 31, 2027 | SUMAGIN, RONEN | reporter.nih.gov |
| Mechanisms of Duox2 variants in the pathogenesis of preclinical IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,026,617 | August 1, 2023 | May 31, 2028 | KAO, JOHN Y | reporter.nih.gov |
| Novel mechanisms protecting the gut from TNF | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,023,225 | July 18, 2023 | June 30, 2028 | SONNENBERG, GREGORY F | reporter.nih.gov |
| Studies of a new checkpoint regulator in the control of intestinal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,018,750 | June 7, 2021 | May 31, 2027 | ZHANG, ZHIQIANG | reporter.nih.gov |
| Mitonuclear Communication During the Pathogenesis of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,012,820 | January 1, 2020 | July 31, 2030 | MOLLEN, KEVIN P | reporter.nih.gov |
| Predevelopment of VV8220, a Gut-selective CRAC Channel Therapeutic for Ulcerative Colitis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,999,994 | May 1, 2022 | July 31, 2027 | GREENBERG, MILTON L | reporter.nih.gov |
| Selective targeting of high affinity alpha4 integrins as a safe treatment strategy for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $1,996,323 | September 16, 2020 | June 30, 2026 | WOODSIDE, DARREN G | reporter.nih.gov |
| T cell Tolerance to Enteric Commensal Bacteria | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,989,382 | June 9, 2021 | September 30, 2025 | MOON, JAMES J | reporter.nih.gov |
| The Role of Layilin as a Novel Regulator of Platelet Activation and Thromboinflammation | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,982,004 | June 1, 2023 | April 30, 2028 | PETREY, AARON CHRISTOPHER | reporter.nih.gov |
| InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammation | NIH | National Center for Advancing Translational Sciences | 2022 to 2023 | $1,980,716 | May 1, 2022 | January 31, 2025 | THELIN, BILL | reporter.nih.gov |
| Robust quantitative MR imaging markers of response to therapy in Crohn’s Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,968,390 | April 1, 2021 | December 31, 2026 | KURUGOL, SILA | reporter.nih.gov |
| High throughput functional studies of IBD-associated GWAS variants | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,964,178 | April 1, 2023 | January 31, 2027 | SHEIKH, SHEHZAD Z. | reporter.nih.gov |
| Gene Regulation in Innate Immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,963,099 | March 1, 2006 | November 30, 2024 | FITZGERALD, KATHERINE A. | reporter.nih.gov |
| Pathway-guided treatment of immune checkpoint inhibitor therapy-induced colon toxicity | NIH | National Cancer Institute | 2023 to 2025 | $1,958,768 | August 1, 2023 | July 31, 2028 | WU, JENNIFER | reporter.nih.gov |
| PARP1 and PARylation as novel effectors of gut inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,948,301 | June 1, 2023 | March 31, 2027 | KIELA, PAWEL R | reporter.nih.gov |
| Inflammatory cascades disrupt Treg function through epigenetic mechanisms | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,945,746 | February 10, 2021 | January 31, 2026 | FAUBION, WILLIAM A | reporter.nih.gov |
| Complement and Circadian Interactions in Inflammation and Immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,941,040 | April 15, 2021 | March 31, 2026 | MAHAN, KRISTIN ECKEL | reporter.nih.gov |
| Polarity proteins and intestinal mucosal responses to inflammation and injury | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,940,569 | April 1, 2022 | February 28, 2026 | NUSRAT, ASMA | reporter.nih.gov |
| Intestinal O-GlcNAc signaling and mucosal host defense | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,938,956 | February 23, 2022 | January 31, 2027 | RUAN, HAI-BIN | reporter.nih.gov |
| Genetic determinants of Bacteroides vulgatus colonization fitness and host inflammatory responses | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,933,487 | April 1, 2023 | March 31, 2027 | RAWLS, JOHN F | reporter.nih.gov |
| Integrin αEβ7-dependent IgA transcytosis during homeostasis and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,930,504 | March 15, 2022 | January 31, 2027 | RIVERA-NIEVES, JESUS | reporter.nih.gov |
| Indole dysbiosis and mucosal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,930,131 | June 1, 2012 | December 31, 2028 | COLGAN, SEAN P | reporter.nih.gov |
| Gut Dysbiosis and Cardiac Remodeling in IBD | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,928,316 | September 1, 2020 | August 31, 2025 | LI, QINGJIE | reporter.nih.gov |
| The Inflammasome in the Regulation of Intestinal Glucose Homeostasis, Microbiota and Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,928,308 | March 9, 2021 | February 28, 2026 | ZAKI, HASAN | reporter.nih.gov |
| Novel Post-surgical Incision Management Device to Prevent Ostomy Complications | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,909,235 | March 1, 2023 | February 28, 2027 | OBST, ANDREW T | reporter.nih.gov |
| Novel biomaterials for IBD treatment | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,903,299 | May 1, 2020 | April 30, 2024 | MOON, JAMES J. | reporter.nih.gov |
| Role of sensory nerves in perivascular inflammation and vasomotor dysfunction with inflammatory bowel disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $1,884,782 | April 1, 2021 | March 31, 2027 | BOERMAN, ERIKA MARY | reporter.nih.gov |
| A nanofiber-hydrogel composite plug for perianal fistula repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,883,553 | March 1, 2023 | February 28, 2027 | MAO, HAI-QUAN | reporter.nih.gov |
| Exploiting metabolic vulnerabilities of CD4 T cell subsets to control inflammatory disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,882,536 | April 1, 2015 | June 30, 2025 | RATHMELL, JEFFREY C | reporter.nih.gov |
| Bacteriophage pathobiology of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,875,144 | May 6, 2020 | February 28, 2025 | ROUND, JUNE LOUISE | reporter.nih.gov |
| Septins in intestinal fibrosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,865,031 | May 1, 2023 | April 30, 2027 | RIEDER, FLORIAN | reporter.nih.gov |
| Clinical Trial of ENhancing Recovery in CHildren Undergoing Surgery - ENRICH-US | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,861,857 | September 9, 2019 | June 30, 2025 | RAVAL, MEHUL V. | reporter.nih.gov |
| Molecular Mechanisms of Programmed Necrosis Execution | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,855,117 | September 20, 2022 | July 31, 2027 | NAJAFOV, AYAZ | reporter.nih.gov |
| Polymicrobial interactions in Crohn's Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,852,209 | July 8, 2019 | June 30, 2025 | GHANNOUM, MAHMOUD A | reporter.nih.gov |
| A Novel Role for PTPN2 in Intestinal Epithelial Barrier Regulation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,850,977 | April 5, 2012 | May 31, 2027 | MCCOLE, DECLAN | reporter.nih.gov |
| Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,850,523 | August 15, 2019 | May 31, 2025 | HUANG, JING | reporter.nih.gov |
| Elucidating the role of gut microbiota in colitis-associated colorectal cancer | NIH | National Cancer Institute | 2023 to 2025 | $1,850,100 | January 1, 2023 | December 31, 2027 | CHEN, RU | reporter.nih.gov |
| The role of IL-1ß-inducing pathobionts in the pathogenesis of Crohn’s disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,843,192 | August 1, 2017 | March 31, 2027 | KAMADA, NOBUHIKO | reporter.nih.gov |
| TL1A Regulation of Group 3 Innate Lymphoid Cells in Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,839,490 | April 10, 2020 | April 30, 2029 | LONGMAN, RANDY S | reporter.nih.gov |
| Uncovering the hidden universe of metabolite-specific T lymphocytes,using human multiorgan microphysiological systems. | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,827,665 | July 1, 2022 | June 30, 2027 | TRAPECAR, MARTIN | reporter.nih.gov |
| Harnessing the power of p53 with Panaxynol from American Ginseng to suppress colitis and prevent colon cancer | NIH | National Cancer Institute | 2021 to 2024 | $1,813,414 | January 1, 2020 | December 31, 2024 | HOFSETH, LORNE J | reporter.nih.gov |
| Statistical Methods for Microbiome and Metagenomics | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,807,642 | September 15, 2017 | August 31, 2026 | LEE, HONGZHE | reporter.nih.gov |
| Vitamin D Receptor Regulation of Microbiota in Intestinal Epithelia | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,798,591 | September 15, 2023 | July 31, 2028 | SUN, JUN | reporter.nih.gov |
| Systematic dissection of gut cellular circuits [at single cell resolution] | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $1,795,970 | August 1, 2017 | May 31, 2023 | XAVIER, RAMNIK J | reporter.nih.gov |
| The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,790,331 | February 1, 2021 | June 4, 2023 | SWANSON, GARTH R | reporter.nih.gov |
| Autophagy and LC3-associated phagocytosis in intestinal epithelial cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,785,473 | August 1, 2022 | May 31, 2027 | WILSON, JEAN M | reporter.nih.gov |
| The role of HIF2alpha in colon carcinogenesis | NIH | National Cancer Institute | 2021 to 2025 | $1,782,443 | July 6, 2010 | June 30, 2026 | SHAH, YATRIK M | reporter.nih.gov |
| Safety and Efficacy Trial of the ColoSeal ICD System for the Treatment of Rectal Cancer Patients | NIH | National Cancer Institute | 2024 to 2025 | $1,767,129 | September 20, 2024 | August 31, 2026 | FONG, KENTON DODYAN | reporter.nih.gov |
| Characterizing neurogenic progenitors in the adult intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,766,773 | January 1, 2020 | December 31, 2027 | GOLDSTEIN, ALLAN M | reporter.nih.gov |
| Mechanisms associated with diet-induced colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,766,652 | February 1, 2020 | July 31, 2024 | LIRA, SERGIO A. | reporter.nih.gov |
| Hypoxia, HIF, and Mucosal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,761,297 | September 25, 1995 | March 31, 2026 | COLGAN, SEAN P | reporter.nih.gov |
| Understanding the Mechanism of a Gut Microbial Genotoxin Involved in Colorectal Carcinogenesis | NIH | National Cancer Institute | 2021 to 2025 | $1,752,081 | July 1, 2016 | January 31, 2027 | BALSKUS, EMILY PATRICIA | reporter.nih.gov |
| IBD Gene Mapping by Clinical and Population Subset | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,737,797 | September 30, 2022 | June 30, 2027 | BRANT, STEVEN R | reporter.nih.gov |
| Celiac and inflammatory bowel diseases: functional post-GWAS approach | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,722,912 | August 19, 2024 | July 31, 2029 | TYCKO, BENJAMIN | reporter.nih.gov |
| Granzyme B PET imaging as a marker of inflammatory bowel disease activity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,722,828 | September 4, 2020 | May 31, 2025 | MAHMOOD, UMAR | reporter.nih.gov |
| Enteric glia and visceral pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,715,750 | March 1, 2024 | February 28, 2028 | GULBRANSEN, BRIAN D. | reporter.nih.gov |
| A novel, pleiotropic oral drug class that inhibits gut migration of activated T cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,712,226 | September 15, 2024 | July 31, 2027 | THACHER, SCOTT MCNEAR | reporter.nih.gov |
| Two novel threonine phosphorylations of STAT2 impact inflammatory responses to bacterial infection. | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,687,938 | August 7, 2020 | July 31, 2024 | STARK, GEORGE ROBERT | reporter.nih.gov |
| Intestinal Homeostasis Induced by Commensals | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,680,144 | July 15, 2020 | April 30, 2025 | MCCORMICK, BETH A | reporter.nih.gov |
| Colonic epithelial wound healing by anal transitional cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,669,452 | April 1, 2023 | March 31, 2028 | LIU, CAMBRIAN YANGSHAO | reporter.nih.gov |
| The impact of ER stress on Salmonella Typhimurium infections | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,664,730 | September 20, 2022 | July 31, 2027 | KEESTRA-GOUNDER, ARINA MARIJKE | reporter.nih.gov |
| Unraveling the enzymatic pathway of gut bacterial mucus degradation to treat inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,661,886 | July 1, 2020 | December 31, 2024 | MARTENS, ERIC C | reporter.nih.gov |
| Microbiome Driven Proteolysis as a Contributing Factor to Severity of Ulcerative Colitis Disease Activity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $1,598,397 | August 1, 2022 | May 31, 2026 | GONZALEZ, DAVID J | reporter.nih.gov |
| Engineered Mesenchymal Stromal Cells for Enhanced Immunosuppression | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,584,969 | July 11, 2024 | May 31, 2029 | KENDERIAN, SAAD J. | reporter.nih.gov |
| The miR-20/c-Myc/E2F Regulatory Axis is Critical for the Tumor Promoting Activity of Inflammatory Fibroblasts in Colitis-Associated Cancer | NIH | National Cancer Institute | 2021 to 2023 | $1,582,909 | March 1, 2019 | August 31, 2025 | HUANG, EMINA HUI-NA | reporter.nih.gov |
| Innate immune responses to tissue infection by intestinal fungi inhibit wound repair | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,580,412 | November 14, 2023 | October 31, 2028 | STAPPENBECK, THADDEUS S | reporter.nih.gov |
| Automated Measurement of Bowel Damage Using Enterography Imaging to Predict Clinical Outcomes in Crohn’s Disease. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,578,048 | July 1, 2020 | April 30, 2026 | STIDHAM, RYAN WILLIAM | reporter.nih.gov |
| Role of innate immunity and the microbiome in colitis-associated dysplasia | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,577,776 | September 1, 2014 | April 30, 2027 | ABREU, MARIA TERESA | reporter.nih.gov |
| Host-Microbiota-Diet Interactions in Metabolic Syndrome and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,567,538 | April 15, 2010 | December 31, 2024 | GEWIRTZ, ANDREW T | reporter.nih.gov |
| Creeping fat and Crohn's disease associated strictures | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,556,335 | July 15, 2020 | March 31, 2026 | RIEDER, FLORIAN | reporter.nih.gov |
| Chloroquine-based polymer particles as oral non-absorbable treatment of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,552,302 | April 1, 2020 | February 28, 2026 | OUPICKY, DAVID | reporter.nih.gov |
| Dissecting the impact of immune environment on Candida albicans pathogenic potential in the gut | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,537,353 | September 1, 2023 | August 31, 2028 | OST, KYLA | reporter.nih.gov |
| Immunoregulatory roles for exosomes in the gastrointestinal tract | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,534,086 | June 10, 2024 | April 30, 2029 | O'CONNELL, RYAN M | reporter.nih.gov |
| SMAD4 regulation of colon epithelial cell inflammatory responses | NIH | National Cancer Institute | 2021 to 2023 | $1,533,094 | July 1, 2019 | June 30, 2024 | MEANS, ANNA L | reporter.nih.gov |
| A comprehensive platform for novel therapy development from the microbiome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $1,532,813 | September 20, 2017 | June 30, 2024 | HUTTENHOWER, CURTIS | reporter.nih.gov |
| A role for the stomach in protection from colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,519,827 | May 1, 2020 | January 31, 2025 | BOONE, DAVID L. | reporter.nih.gov |
| MicroRNA control of tumor-promoting inflammation in colon cancer | NIH | National Cancer Institute | 2022 to 2025 | $1,518,283 | February 8, 2022 | January 31, 2027 | GOPAL, MURUGAIYAN | reporter.nih.gov |
| Mitochondrial Mechanisms Promoting Innate and Intestinal Immunity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,515,170 | March 15, 2023 | January 31, 2027 | ABRAHAM, CLARA | reporter.nih.gov |
| Role of microbiota, host genetics and mesenteric adipose in Crohn's disease fibrosis and post-op recurrence. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,514,700 | January 20, 2020 | December 31, 2025 | DEVKOTA, SUZANNE | reporter.nih.gov |
| STING signaling in T cells regulation of intestinal homeostasis and inflammatorybowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,511,796 | July 1, 2020 | October 1, 2023 | CONG, YINGZI | reporter.nih.gov |
| Mechanisms of action for the IBD-risk gene INAVA: an epithelial guard receptor for inflammation and integrity of the intestinal barrier | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,501,754 | July 1, 2020 | May 31, 2025 | LENCER, WAYNE I | reporter.nih.gov |
| Defining a novel mechanism of mucosal healing | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,498,524 | February 1, 2019 | January 31, 2025 | SONNENBERG, GREGORY F | reporter.nih.gov |
| Microbiota-mediated fibrotic remodeling in the inflamed intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,497,126 | June 1, 2020 | May 31, 2025 | ARTHUR, JANELLE C | reporter.nih.gov |
| Molecular mayhem: Immune modulation and eicosanoid signaling during infection | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,492,485 | July 1, 2020 | December 31, 2025 | DILLMAN, ADLER RAY | reporter.nih.gov |
| Regulation of Intestinal Immunity and Repair by Integrins | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,486,099 | June 17, 2024 | April 30, 2028 | LACY-HULBERT, ADAM | reporter.nih.gov |
| Examining a Unique Contractile Injection System Mediating Host-Microbe Interactions | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,483,588 | August 1, 2022 | May 31, 2027 | SHIKUMA, NICHOLAS J | reporter.nih.gov |
| Central metabolism of Salmonella in the inflamed gut | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,472,554 | May 1, 2015 | July 31, 2030 | WINTER, SEBASTIAN E | reporter.nih.gov |
| Genomic and Immunologic Characterization of Inflammatory Bowel Disease and its Phenotypes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,470,541 | September 30, 2002 | June 30, 2027 | SILVERBERG, MARK S. | reporter.nih.gov |
| Modulation of Macrophage Polarization by Heterotrimeric G proteins: Implications of Gastrointestinal Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,461,612 | May 21, 2019 | April 30, 2026 | GHOSH, PRADIPTA | reporter.nih.gov |
| gd IELs in chronic ileitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,441,543 | July 1, 2023 | April 30, 2027 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| The role of autophagy gene Atg16L1 in allogeneic hematopoietic stem cell transplantation - Renewal - 1 | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,438,518 | September 1, 2015 | November 30, 2023 | CADWELL, KEN HASHIGIWA | reporter.nih.gov |
| Contributions of the enterocyte brush border to intestinal health and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,425,632 | July 1, 2023 | April 30, 2027 | VANDUSSEN, KELLI LYNN | reporter.nih.gov |
| Cytokines and Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,412,135 | July 3, 1990 | April 30, 2024 | COMINELLI, FABIO | reporter.nih.gov |
| Microbial ecology of the inflamed intestine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,411,946 | September 24, 2018 | August 31, 2024 | AHMER, BRIAN M | reporter.nih.gov |
| A Novel Immunological Probiotic for Treating Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,409,741 | July 1, 2018 | September 30, 2023 | FANGER, GARY | reporter.nih.gov |
| Oral elafin formulation for intestinal fibrosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,403,285 | April 1, 2022 | February 28, 2027 | KOON, HON WAI | reporter.nih.gov |
| Gut Microbe-Derived Nitric Oxide As A Signal To Host: Role In Normal Physiology And In Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,402,632 | March 1, 2021 | February 28, 2025 | STAMLER, JONATHAN S. | reporter.nih.gov |
| Actions of Resolvins on Intestinal Inflammation and Pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,399,647 | April 1, 2020 | March 31, 2025 | WILEY, JOHN W | reporter.nih.gov |
| Functional characterization of CARD9 genetic variants in fungal immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,396,562 | February 8, 2018 | January 31, 2024 | XAVIER, RAMNIK J | reporter.nih.gov |
| p38gamma MAPK signaling promotes intestinal tumorigenesis | NIH | National Cancer Institute | 2021 to 2025 | $1,395,284 | June 15, 2020 | May 31, 2026 | CHEN, GUAN | reporter.nih.gov |
| Small molecule inhibitor of CD40 signaling for the control of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,392,325 | August 1, 2022 | May 31, 2027 | SUBAUSTE, CARLOS S | reporter.nih.gov |
| Determining the Role of apoC-III in the Immune System | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,382,422 | August 1, 2019 | May 31, 2025 | KOHAN, ALISON BLOOM | reporter.nih.gov |
| Predicting Clinical Phenotypes in Crohn's Disease Using Machine Learning and Single-Cell 'omics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $1,381,450 | May 1, 2023 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Intestinal mucosal wound resealing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,381,035 | August 1, 1998 | March 31, 2025 | NUSRAT, ASMA | reporter.nih.gov |
| A Novel Synthetically Engineered Oral Immunotherapy for Treating Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,377,944 | September 16, 2024 | June 30, 2027 | FANGER, GARY | reporter.nih.gov |
| Cross-talk between the colon epithelium, colon afferents and sympathetic neurons regulate pain in the normal and inflamed colon | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,372,165 | May 5, 2020 | April 30, 2025 | DAVIS, BRIAN M | reporter.nih.gov |
| Preclinical validation of oral therapeutic lead proteins targeting epithelial GM1 ganglioside for ulcerative colitis therapy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,370,301 | June 20, 2020 | March 31, 2026 | MATOBA, NOBUYUKI | reporter.nih.gov |
| Mechanisms of fungal involvement during intestinal disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,348,169 | May 8, 2020 | February 28, 2025 | ROUND, JUNE LOUISE | reporter.nih.gov |
| Interplay of processed diet, gut microbiota, and interferon-linked mucosal immunity in the onset and prevalence of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,346,565 | April 1, 2023 | March 31, 2028 | SINGH, VISHAL | reporter.nih.gov |
| Immune regulation of tissue iron in health and disease | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,346,392 | June 9, 2021 | May 31, 2026 | BESSMAN, NICHOLAS J. | reporter.nih.gov |
| Optimization of small molecule immunomodulators as combination therapy for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,336,560 | April 10, 2024 | February 28, 2029 | GABR, MOUSTAFA | reporter.nih.gov |
| A probiotic-derived protein regulates epigenetic programming in intestinal epithelial cells for long-term prevention of colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,329,702 | April 1, 2009 | March 31, 2025 | YAN, FANG | reporter.nih.gov |
| CD39 in gamma delta intraepithelial lymphocyte function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,328,326 | August 1, 2024 | May 31, 2028 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| Genetic and Small Molecule Regulation of Mechanisms of Crohn’s Disease Stricture Formation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,323,025 | May 1, 2024 | April 30, 2028 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Role for myeloid acid ceramidase in colon inflammation and cancer | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,315,037 | April 1, 2022 | March 31, 2027 | SNIDER, ASHLEY JONES | reporter.nih.gov |
| Integrated high-throughput functional assays to identify ulcerative colitis causal risk variants | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,314,256 | August 1, 2018 | April 30, 2024 | YU, HAIYUAN | reporter.nih.gov |
| The Role of the Smcr8-Wdr41-C9orf72 (SWC) Complex in the Maintenance of Intestinal Homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,312,569 | June 1, 2020 | February 28, 2025 | TURER, EMRE EROL | reporter.nih.gov |
| Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities | NIH | National Cancer Institute | 2021 to 2024 | $1,290,653 | July 20, 2021 | January 31, 2025 | HANKS, BRENT ALLEN | reporter.nih.gov |
| Postprandial activation of hyaluronan-MARCO axis contributes to systemic chronic inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,284,096 | June 15, 2023 | April 30, 2028 | ZHU, YI | reporter.nih.gov |
| Whole-Room Calorimeter | NIH | Office of the Director, National Institutes of Health | 2022 | $1,284,000 | September 15, 2022 | September 14, 2025 | CHAPMAN, ARLENE B | reporter.nih.gov |
| Role of neutrophil extracellular traps (NETs) in Inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,279,974 | February 15, 2023 | January 31, 2027 | VIJAY-KUMAR, MATAM | reporter.nih.gov |
| Sphingolipids, Dietary Fatty Acids, and Intestinal Pathophysiology | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,279,167 | December 1, 2021 | November 30, 2026 | SNIDER, ASHLEY JONES | reporter.nih.gov |
| Intestinal uptake, translocation, biodistribution, and toxicity of ingested environmentally relevant micro-nanoplastics (MNPs) and the role of inflammation using advanced cellular and in vivo models | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $1,276,583 | July 15, 2024 | June 30, 2029 | DEMOKRITOU, PHILIP | reporter.nih.gov |
| Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,270,015 | September 20, 2019 | June 30, 2024 | NUNEZ, GABRIEL | reporter.nih.gov |
| Comparative effectiveness research in Hispanic patients with inflammatory bowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,262,607 | January 18, 2024 | November 30, 2028 | SINGH, SIDDHARTH | reporter.nih.gov |
| Prioritization and Bioactivity Characterization of Novel Bile Acids Produced by the Microbiome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,259,750 | August 1, 2024 | May 31, 2029 | QUINN, ROBERT ANDREW | reporter.nih.gov |
| A magnetic capsule endoscope for colonoscopy in patients with inflammatory bowel disease | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $1,258,230 | September 18, 2014 | December 31, 2025 | OBSTEIN, KEITH L | reporter.nih.gov |
| IL-36 cytokines and gut immunity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,255,633 | December 24, 2019 | November 30, 2024 | DENNING, TIMOTHY L | reporter.nih.gov |
| Epigenetic regulation of intestinal tuft cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,255,082 | August 1, 2024 | June 30, 2028 | ALENGHAT, THERESA | reporter.nih.gov |
| Project Title: Low-dose erlotinib and mesalamine for prevention of colitis-associated colorectal cancer (CAC) | NIH | National Cancer Institute | 2024 to 2025 | $1,246,808 | September 25, 2025 | March 24, 2027 | VILAR SANCHEZ, EDUARDO | reporter.nih.gov |
| Intestinal IL-17RA signaling and mucosal host defense | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,238,952 | July 1, 2019 | April 30, 2025 | KUMAR, PAWAN | reporter.nih.gov |
| Ligand and transcriptional regulation of the nuclear receptor RORa on TH17 cell development and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,236,144 | April 1, 2024 | January 31, 2029 | SOLT, LAURA A | reporter.nih.gov |
| Dysbiosis in Hirschsprung Associated Enterocolitis Pathogenesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,224,406 | April 1, 2020 | January 31, 2024 | GOSAIN, ANKUSH | reporter.nih.gov |
| MTGs in Intestinal Biology and Injury Responses | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,223,368 | July 1, 2024 | May 31, 2028 | WILLIAMS, CHRISTOPHER S. | reporter.nih.gov |
| Nuclear Receptor Networks in Mucosal Immune Regulation | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,217,517 | May 1, 2023 | April 30, 2026 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| TVP23B and Golgi Mediated Control of Intestinal Secretory Cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,198,322 | January 1, 2024 | December 31, 2027 | TURER, EMRE EROL | reporter.nih.gov |
| Rapid and Robust Pediatric MRI | NIH | National Institute of Biomedical Imaging and Bioengineering | 2024 to 2025 | $1,197,186 | August 1, 2024 | April 30, 2028 | VASANAWALA, SHREYAS S | reporter.nih.gov |
| Characterization of a commensal enteric virus | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,195,175 | September 20, 2011 | June 30, 2030 | CADWELL, KEN HASHIGIWA | reporter.nih.gov |
| Supplement: Epigenetics of the Human Gut Microbiome | NIH | National Institute of Environmental Health Sciences | 2021 to 2023 | $1,193,188 | September 20, 2019 | May 31, 2025 | DEDON, PETER C | reporter.nih.gov |
| Mechanisms by which human milk-derived oligosaccharides protect intestinal barrier and attenuate inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,190,720 | May 15, 2024 | March 31, 2028 | YAN, FANG | reporter.nih.gov |
| Peer Mentoring to Improve Self-Management in Youth with IBD | NIH | National Institute of Nursing Research | 2021 to 2022 | $1,187,687 | April 12, 2018 | February 29, 2024 | MACKNER, LAURA M | reporter.nih.gov |
| Preclinical Validation of Novel Gut-Restricted LRRK2 Inhibitors as Therapeutic Leads for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $1,183,936 | September 30, 2022 | June 30, 2026 | PETER, INGA | reporter.nih.gov |
| The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,166,868 | April 10, 2020 | January 31, 2025 | COATES, MATTHEW D | reporter.nih.gov |
| CD4 T cell stemness and inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,157,862 | September 1, 2020 | May 31, 2025 | HARRINGTON, LAURIE ELLEN | reporter.nih.gov |
| Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,151,436 | April 1, 2023 | January 31, 2028 | SCHMIEDEL, BENJAMIN JOACHIM | reporter.nih.gov |
| Immune Outcomes to Neonatal Antigen Delivery in the Intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,149,972 | July 15, 2023 | April 30, 2028 | KNOOP, KATHRYN A | reporter.nih.gov |
| Mechanisms of TL1A-driven Paneth Cell dysfunction in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,147,500 | January 1, 2020 | December 31, 2024 | TARGAN, STEPHAN R. | reporter.nih.gov |
| Dissecting functions of IL-23-dependent inflammatory Th17 cells | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $1,145,651 | November 25, 2022 | October 31, 2028 | HE, ZHIHENG | reporter.nih.gov |
| Equipment Supplement: Maintenance of Adhesion and Barrier Function during Epithelial Cell Shape Changes | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,142,613 | August 1, 2015 | August 31, 2024 | MILLER, ANN LOUISE | reporter.nih.gov |
| Effects of host endocannabinoid signaling on Enterobacteriaceae infection | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,140,243 | June 6, 2024 | April 30, 2029 | ELLERMANN, MELISSA | reporter.nih.gov |
| Mechanistic Characterization of the IBD Risk Gene, PTPN2, as a Novel Susceptibility Marker for Increased SARS-CoV-2 Infection | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,135,627 | August 1, 2021 | June 30, 2025 | MCCOLE, DECLAN | reporter.nih.gov |
| Carbohydrate Structure Controls on Human Gut Microbial Ecology | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,127,763 | August 9, 2019 | June 30, 2025 | LINDEMANN, STEPHEN ROBERT | reporter.nih.gov |
| Intestinal lysozyme controls mucosal immune response to microbiota | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,115,623 | July 1, 2019 | June 30, 2025 | GAO, NAN | reporter.nih.gov |
| Investigating imitation SWI chromatin remodeling complexes in mammalian tissue regeneration | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,106,813 | July 1, 2020 | June 30, 2024 | ZHU, HAO | reporter.nih.gov |
| Targeting professional APCs using Fasciola hepatica FABP to suppresses inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,106,359 | August 1, 2020 | July 31, 2025 | ESPINO, ANA M | reporter.nih.gov |
| Characterization of a commensal enteric virus | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,102,694 | September 20, 2011 | August 31, 2023 | CADWELL, KEN HASHIGIWA | reporter.nih.gov |
| Characterization of lectins to understand human microbiome functions and develop live biotherapeutics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,100,528 | May 1, 2023 | February 29, 2028 | COHEN, LOUIS JARED | reporter.nih.gov |
| Roles for Adenomatous polyposis coli in colon injury prevention and wound healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $1,099,503 | September 22, 2022 | July 31, 2025 | NEUFELD, KRISTI L | reporter.nih.gov |
| Metabolic Regulation of Colonic Senescence and Pathological Implications: Epithelial and Microbial Interactions | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,099,018 | March 1, 2024 | January 31, 2028 | LI, YAN CHUN | reporter.nih.gov |
| Modulation of colonocyte barrier function and signaling by cytomegalovirus infection | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,086,202 | April 1, 2024 | March 31, 2028 | WILSON, JEAN M | reporter.nih.gov |
| Paneth cell phenotype as a predictive biomarker for ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,085,430 | September 24, 2020 | July 31, 2025 | LIU, TA-CHIANG | reporter.nih.gov |
| Activation of deep crypt secretory cells in colonic inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,081,261 | September 15, 2024 | June 30, 2029 | SCHUMACHER, MICHAEL ANDREW | reporter.nih.gov |
| AHR-NLRP6 interactions in gut barrier dysfunction and colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,080,828 | May 1, 2024 | April 30, 2028 | JALA, VENKATAKRISHNA RAO | reporter.nih.gov |
| Gut microbiota metabolite sensing licenses IEC to cross talk with T cells to inhibit intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,073,997 | February 15, 2023 | January 31, 2027 | CONG, YINGZI | reporter.nih.gov |
| CD74 and Wound Healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,069,998 | August 16, 2022 | May 31, 2027 | MOONAH, SHANNON | reporter.nih.gov |
| Pathogenic Role of Mechanical Stress in Fibrosis and Tissue Remodeling in Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,066,500 | April 21, 2020 | January 31, 2026 | SHI, XUAN-ZHENG PETER | reporter.nih.gov |
| Plasticity of Innate Lymphoid Cells: Mechanisms and Biological Impact | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,063,125 | April 1, 2020 | March 31, 2026 | COLONNA, MARCO | reporter.nih.gov |
| Cellular and molecular mechanisms of cigarette smoking-induced Paneth cell abnormality | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,063,125 | July 1, 2020 | April 30, 2025 | LIU, TA-CHIANG | reporter.nih.gov |
| Role of SLCO3A1 in macrophage metabolite sensing and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,035,408 | January 6, 2023 | December 31, 2026 | IP, W. K. EDDIE | reporter.nih.gov |
| Microbiota Specific T Cell Selection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,025,733 | December 3, 2018 | November 30, 2024 | BETTINI, MATTHEW | reporter.nih.gov |
| Development of IMYX-3 for the Treatment of Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $1,024,862 | September 15, 2025 | August 31, 2027 | ENG, CHRISTINA | reporter.nih.gov |
| A randomized, placebo-controlled clinical trial examining the efficacy of Fecal Microbiota Transplantation (FMT) and subsequent dietary fiber in patients with moderate ulcerative colitis (MINDFUL) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,017,000 | April 6, 2021 | March 31, 2025 | LONGMAN, RANDY S | reporter.nih.gov |
| Regulation of colitis associated with acute kidney injury by the Wnt pathway | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,016,400 | January 10, 2020 | December 31, 2024 | MANICASSAMY, SANTHAKUMAR | reporter.nih.gov |
| The function of lysophosphatidic acid receptor LPA5R in intestinal inflammation and epithelial damage | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,014,004 | September 20, 2018 | May 31, 2024 | YUN, CHANGHYON CHRIS | reporter.nih.gov |
| Actin methylation as a novel mechanism that regulates gut barrier integrity and repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,011,436 | January 15, 2024 | December 31, 2028 | IVANOV, ANDREI IVANOVICH | reporter.nih.gov |
| Microbiota-Immune Interactions in CTLA-4 Antibody Blockade-Induced Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,009,405 | July 1, 2024 | April 30, 2029 | NUNEZ, GABRIEL | reporter.nih.gov |
| Genetic variants guiding pathogenicity of colitogenic T cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,007,304 | September 1, 2024 | June 30, 2027 | RAY, JOHN PHILIP | reporter.nih.gov |
| The Role of the Adenosine Receptor in Th Cell Development and Function | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,007,234 | December 6, 2017 | November 30, 2024 | ERNST, PETER B. | reporter.nih.gov |
| Immune regulation of intestinal health and disease | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,001,744 | April 1, 2016 | October 31, 2028 | SONNENBERG, GREGORY F | reporter.nih.gov |
| GPR120 regulation of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,001,738 | May 1, 2020 | March 31, 2024 | CONG, YINGZI | reporter.nih.gov |
| Treatment Approaches and Outcomes in Pouch-related Disorders after Colectomy for Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,000,260 | February 5, 2021 | November 30, 2025 | BARNES, EDWARD | reporter.nih.gov |
| Systems approach to elucidate the microbiome's influence on the development of food allergies early in life | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $998,240 | December 14, 2020 | November 30, 2025 | MARTIN, VICTORIA MACKENZIE | reporter.nih.gov |
| The Role of Enteric Infection in Flares of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $997,800 | January 15, 2021 | February 28, 2026 | AXELRAD, JORDAN ERIC | reporter.nih.gov |
| Intestinal 5-HT Transporter: A novel therapeutic target for GI disorders | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $996,519 | January 1, 2014 | December 31, 2023 | GILL, RAVINDER K | reporter.nih.gov |
| Spatial subcellular mapping of the intestinal LncRNAome | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $984,000 | January 23, 2024 | November 30, 2028 | GALIA, LIRAZ | reporter.nih.gov |
| Gene Regulation as a Foundation for Autoimmune Disease Prevention | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $963,738 | June 1, 2017 | May 31, 2023 | WEIRAUCH, MATTHEW TYSON | reporter.nih.gov |
| Role of IRGM proteins in immunity to enteric bacteria | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $961,519 | August 1, 2019 | July 31, 2025 | TAYLOR, GREGORY A | reporter.nih.gov |
| Trans-ancestry, single-cell multiomics dissection of IBD-associated loci in CD4 memory T cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $954,000 | March 1, 2024 | February 29, 2028 | DUERR, RICHARD H | reporter.nih.gov |
| Early-life Risk Factors for Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $951,196 | August 12, 2021 | July 31, 2026 | AGRAWAL, MANASI | reporter.nih.gov |
| The role of Interleukin 17RB signaling in colorectal cancer progression | NIH | National Cancer Institute | 2021 to 2022 | $947,522 | July 1, 2021 | June 30, 2023 | GRIVENNIKOV, SERGEI I | reporter.nih.gov |
| A Heart Rate Variability Biofeedback Enhanced Behavioral Intervention to Improve Psychological and Disease Functioning in Youth with Inflammatory Bowel Disease (IBD) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $947,375 | July 1, 2024 | April 30, 2029 | REED, BONNEY | reporter.nih.gov |
| Immune regulation of tissue iron in health and disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $935,501 | June 9, 2021 | May 31, 2023 | BESSMAN, NICHOLAS J. | reporter.nih.gov |
| Inhibiting Bcl-2-regulated intestinal fibrosis in models of Crohn’s Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $934,680 | July 1, 2018 | May 31, 2024 | HIGGINS, PETER D.R. | reporter.nih.gov |
| Development of novel PD1 agonist therapeutic strategies for inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $927,300 | February 1, 2024 | November 30, 2027 | GOPAL, MURUGAIYAN | reporter.nih.gov |
| Paneth cell heterogeneity in infection and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $925,915 | March 15, 2022 | January 31, 2024 | GAO, NAN | reporter.nih.gov |
| Changes in actin dynamics regulated by villin and gesolin are determinants of cell fate and may be key to gastrointestinal inflammatory disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $923,894 | September 20, 2018 | August 31, 2024 | KHURANA, SEEMA | reporter.nih.gov |
| Morning Light Treatment for Inflammatory Bowel Disease: A Pilot Clinical Trial | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $923,520 | September 1, 2023 | December 31, 2026 | BURGESS, HELEN JULIA | reporter.nih.gov |
| Multi-omic characterization of genetic variants in IBD risk loci | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $919,886 | March 1, 2024 | February 29, 2028 | FUREY, TERRENCE S. | reporter.nih.gov |
| Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $905,290 | September 18, 2023 | August 31, 2027 | SCHULTZ, KENNETH | reporter.nih.gov |
| Unconventional myosins and the regulation of gut barrier integrity and restitution during inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $905,274 | September 15, 2020 | July 31, 2024 | IVANOV, ANDREI IVANOVICH | reporter.nih.gov |
| Central metabolism of Salmonella in the inflamed gut | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $904,111 | February 24, 2021 | June 30, 2022 | WINTER, SEBASTIAN E | reporter.nih.gov |
| Paneth cell heterogeneity in infection and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $895,175 | March 15, 2022 | January 31, 2026 | GAO, NAN | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $885,846 | September 23, 2021 | September 2, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Macrophage LRRK2 activity regulates gut epithelial homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $882,538 | September 1, 2024 | June 30, 2027 | LIU, TA-CHIANG | reporter.nih.gov |
| Impaired cellular RNA editing as a cause of inflammation in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $880,717 | September 15, 2024 | June 30, 2027 | LI, JIN BILLY | reporter.nih.gov |
| Immune, Microbial, and Metabolic Factors that Impact Clostridioides difficile and Inflammatory Bowel Disease in Children | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $876,123 | December 4, 2020 | November 30, 2025 | NICHOLSON, MARIBETH RUTH | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $874,967 | September 23, 2021 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| REGULATION OF NICHE CELL DIFFERENTIATION TO SUSTAIN INTESTINAL STEM CELL REGENERATION AGAINST GUT INFLAMMATION | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $870,194 | January 1, 2020 | December 31, 2024 | HAN, XIAONAN | reporter.nih.gov |
| Quantitative Ultrasound Imaging Biomarkers of Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $867,754 | March 11, 2019 | December 31, 2024 | CHEN, SHIGAO | reporter.nih.gov |
| Targeted Identification of IBD Risk Gene Variant Impact on Immune-Epithelial Crosstalk and Intestinal Barrier Function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $865,703 | March 1, 2024 | February 28, 2028 | MCCOLE, DECLAN | reporter.nih.gov |
| Agr2 regulates host-microbe responses in Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $859,704 | July 2, 2025 | April 30, 2029 | LONGMAN, RANDY S | reporter.nih.gov |
| Role of Bacteria in Colitis-Associated Colon Cancer | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $858,754 | April 1, 2007 | April 30, 2025 | JOBIN, CHRISTIAN | reporter.nih.gov |
| Regulation and function of innate lymphoid cells in the gut | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $847,500 | August 15, 2011 | February 29, 2024 | ARTIS, DAVID | reporter.nih.gov |
| Autophagy, injury, and plasticity in the intestinal regenerative process | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $836,942 | September 15, 2025 | July 31, 2030 | HAMILTON, KATHRYN ELIZABETH | reporter.nih.gov |
| Mechanisms underlying the functional regulation of the gut microbiota by intestinal epithelial cells to maintain intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $835,564 | September 1, 2025 | June 30, 2030 | O'CONNELL, RYAN M | reporter.nih.gov |
| Mitochondrial Dysfunction and Mitophagy in Ileitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $833,371 | August 15, 2019 | July 31, 2024 | THEISS, ARIANNE L | reporter.nih.gov |
| Digital Biomarkers of Ulcerative Colitis Flare | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $811,856 | September 1, 2021 | June 30, 2026 | HIRTEN, ROBERT | reporter.nih.gov |
| Understanding NLRP6 function in intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $800,348 | July 1, 2019 | April 30, 2023 | CHEN, GRACE Y. | reporter.nih.gov |
| Dietary strategies for rational manipulation of the gut microbiome in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $799,200 | August 1, 2020 | May 31, 2026 | NGUYEN, LONG H | reporter.nih.gov |
| Coordinated matricellular regulation of intestinal injury repair and regeneration | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $795,360 | March 1, 2024 | January 31, 2028 | JUN, JOON-IL | reporter.nih.gov |
| A Novel Approach to Restore Epithelial Barrier Homeostasis to Treat Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $795,004 | September 15, 2019 | November 15, 2022 | GRAHAM, W VALLEN | reporter.nih.gov |
| Targeted Probiotic Yeast for Treating Inflammatory Bowel Diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $790,359 | July 1, 2025 | April 30, 2029 | NGUYEN, JULIANE | reporter.nih.gov |
| Understanding Clostridium difficile Infection in Patients with inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $785,432 | May 1, 2020 | January 31, 2026 | ALLEGRETTI, JESSICA R. | reporter.nih.gov |
| Diet and metabolic factors in the pathogenesis of microscopic colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $784,992 | February 1, 2022 | November 30, 2026 | BURKE, KRISTIN E. | reporter.nih.gov |
| The link between oral bacteria and gut disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $782,216 | January 8, 2019 | December 31, 2024 | KAMADA, NOBUHIKO | reporter.nih.gov |
| Genomic Analysis of Perianal Fistulizing Crohn's Disease across Ancestries | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $771,196 | September 16, 2020 | August 31, 2024 | KUGATHASAN, SUBRA | reporter.nih.gov |
| Characterizing the Biologic Evolution of Crohn's Disease Like Pouch Inflammation in Ulcerative Colitis Patients After Restorative Proctocolectomy with Ileal Pouch Anal Anastomosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $763,616 | February 1, 2022 | January 31, 2027 | KAYAL, MAIA | reporter.nih.gov |
| The role of SPRY2 in the colonic epithelial response to inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $761,092 | August 20, 2019 | May 31, 2025 | FREY, MARK R | reporter.nih.gov |
| POP3 regulates type I interferon and ameliorates intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $758,542 | July 3, 2025 | April 30, 2030 | STEHLIK, CHRISTIAN | reporter.nih.gov |
| Host-Microbiota Interactions in Crohn's Disease-associated Spondyloarthritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $751,598 | April 2, 2018 | January 31, 2023 | LONGMAN, RANDY S | reporter.nih.gov |
| IL1 as a Driver of Mucosal Immune Dysregulation in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $750,700 | January 10, 2022 | February 4, 2027 | MITSIALIS, VANESSA | reporter.nih.gov |
| The impact of inflammation induced alterations to microbially derived bile acids on susceptibility and severity of Clostridioides difficile infection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $749,088 | July 1, 2022 | June 30, 2027 | WINSTON, JENESSA ANDRZEJEWSKI | reporter.nih.gov |
| Oral Protein Therapeutics Against C. difficile Associated Colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $747,660 | September 1, 2021 | August 31, 2023 | CHEN, ZHILEI | reporter.nih.gov |
| Anticoagulant use, safety, and effectiveness for venous thromboembolism prevention in inflammatory bowel disease patients | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $747,000 | August 1, 2023 | July 31, 2027 | DAWWAS, GHADEER K. | reporter.nih.gov |
| Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer | NIH | National Cancer Institute | 2021 to 2022 | $746,393 | August 14, 2018 | July 31, 2024 | MANI, SRIDHAR | reporter.nih.gov |
| Microbiota-sourced purines in gut health and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $738,605 | September 1, 2021 | July 31, 2027 | LEE, JOSEPH SCOTT | reporter.nih.gov |
| Engineering Biologics for treatment of enteric diseases | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $737,316 | November 30, 2023 | October 31, 2028 | CHEN, ZHILEI | reporter.nih.gov |
| Neural interactions with the microbiome and immune system that produce inflammation in Hirschsprung disease models | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $737,041 | August 1, 2022 | July 31, 2025 | SMITH-EDWARDS, KRISTEN MICHELLE | reporter.nih.gov |
| Incorporating Geriatric Constructs into Management of Inflammatory Bowel Diseases in Older Adults | NIH | National Institute on Aging | 2023 to 2025 | $728,368 | September 1, 2023 | May 31, 2028 | KOCHAR, BHARATI | reporter.nih.gov |
| Role of Interferon lambda signaling in mucosal homeostasis and infantile-onset inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $726,020 | September 30, 2020 | July 31, 2026 | OUAHED, JODIE | reporter.nih.gov |
| Aberrant N-glycosylation in Crohn's disease: Opportunity for precision medicine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $725,520 | September 15, 2025 | June 30, 2030 | MELIA, JOANNA MILLER PELOQUIN | reporter.nih.gov |
| Engineered biomimetic materials for intestinal mucosal healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $723,885 | August 17, 2023 | May 31, 2027 | ZHANG, SUFENG | reporter.nih.gov |
| The regulation of gut macrophage’s function by the bile acid receptor FXR | NIH | National Cancer Institute | 2024 to 2025 | $711,412 | May 1, 2024 | April 30, 2029 | FU, TING | reporter.nih.gov |
| The role of local iron homeostasis in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $705,236 | August 6, 2021 | July 31, 2026 | BESSMAN, NICHOLAS J. | reporter.nih.gov |
| AI-Driven Digital Pathology Tool for Evaluating Inflammation and Therapeutic Efficacy in Preclinical Models | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $705,182 | August 1, 2025 | May 31, 2029 | DAVE, MANEESH | reporter.nih.gov |
| microRNA-dependent regulation of intestinal T-cells² | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $699,750 | January 13, 2018 | December 31, 2023 | DE ZOETEN, EDWIN FULCO | reporter.nih.gov |
| Predicting Clinical Phenotypes in Crohn's Disease Using Machine Learning and Single-Cell 'omics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $696,092 | March 25, 2025 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Mechanisms of intestinal epithelial injury in intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $688,392 | January 16, 2020 | November 30, 2024 | KATTAH, MICHAEL GEORGE | reporter.nih.gov |
| Population-Based Characterization of Metabolic Pathways to Predict Pediatric Crohn's Disease Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $688,350 | April 25, 2025 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Primordially conserved principles governing mucosal immune responses to microbiota | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $687,972 | September 1, 2010 | December 31, 2023 | SUNYER, J. ORIOL | reporter.nih.gov |
| Lipid dysregulation of immune mediated intestinal epithelial healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $687,292 | April 7, 2020 | February 28, 2025 | MCALESTER, ANDREA ALYSSA | reporter.nih.gov |
| Intestinal Immune Regulation by IgG and FcRn | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $684,927 | September 1, 1997 | June 30, 2023 | BLUMBERG, RICHARD S | reporter.nih.gov |
| Malassezia Immune Responses as Biomarkers of IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $680,687 | August 15, 2025 | May 31, 2030 | UNDERHILL, DAVID M. | reporter.nih.gov |
| CD4+ Tissue resident memory T-cells in Crohnâs Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $677,055 | September 30, 2020 | July 31, 2025 | BISHU, SHRINIVAS | reporter.nih.gov |
| Role of SCGN in Intestinal Immune Homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $669,600 | March 10, 2021 | February 28, 2026 | SIFUENTES-DOMINGUEZ, LUIS | reporter.nih.gov |
| Targeting gut inflammation through diet: a tailored American diet for patients with ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $667,726 | September 1, 2024 | June 30, 2029 | DAMAS, ORIANA MAZORRA | reporter.nih.gov |
| Regulatory role for an epithelial repair protein, LINGO2, in colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $667,440 | July 1, 2020 | March 31, 2025 | BELLE, NICOLE MALONEY | reporter.nih.gov |
| The Microbiome, Metabolome, and Genome in Multiplex IBD Family Clusters | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $663,444 | August 1, 2022 | May 31, 2027 | SPENCER, ELIZABETH | reporter.nih.gov |
| Plasticity of Type 3 Innate Lymphoid Cells Regulated by Intestinal Microenvironment | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $656,001 | June 1, 2025 | March 31, 2030 | SANO, TERUYUKI | reporter.nih.gov |
| Modulation of Host-Microbe Interactions by Extracellular Purines in the Gastrointestinal Lumen | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $648,172 | March 15, 2020 | February 28, 2026 | KAO, DANIEL JOSEPH | reporter.nih.gov |
| Understanding the Interaction between Host Genetics, Immune response, and Gut Microbes in Post-operative Recurrence of Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $648,000 | March 1, 2024 | February 29, 2028 | LEE, SUN-HO | reporter.nih.gov |
| Understanding hematopoietic stem cell dysfunction in refractory Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $645,617 | July 1, 2025 | April 30, 2030 | COHEN, LOUIS JARED | reporter.nih.gov |
| The impact of diet patterns and PUFA-related polymorphisms on ulcerative colitis in Hispanics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $645,408 | January 14, 2019 | May 31, 2025 | DAMAS, ORIANA MAZORRA | reporter.nih.gov |
| Validation of Immunometabolic NLRX1 Therapeutics for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $643,417 | April 1, 2019 | April 30, 2023 | LEBER, ANDREW | reporter.nih.gov |
| ROLE OF STRESS IN GUT IMMUNE INTERACTIONS WITH COMMENSAL BACTERIA | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $641,222 | July 18, 2018 | June 30, 2023 | NEWBERRY, RODNEY D | reporter.nih.gov |
| Pathogenic Heterogeneity in Mucosal Stem Cells in Pediatric Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $640,193 | August 10, 2018 | June 30, 2024 | XIAN, WA | reporter.nih.gov |
| Engineered Probiotics for Closed-Loop Control of Disease-Associated Gut Metabolites in Gut-On-Chip Models | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2024 | $636,250 | September 15, 2022 | June 30, 2026 | WOOLSTON, BENJAMIN MICHAEL | reporter.nih.gov |
| Anti-inflammatory microbiome-substrate-host interactions | NIH | National Center for Complementary & Integrative Health | 2022 | $632,593 | September 26, 2022 | April 30, 2025 | TALCOTT, SUSANNE U | reporter.nih.gov |
| STAT4 regulation of Th17 pathogenicity | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $632,423 | August 1, 2025 | July 31, 2030 | HARRINGTON, LAURIE ELLEN | reporter.nih.gov |
| Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis: A Randomized Crossover Trial | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $628,000 | April 7, 2021 | March 31, 2023 | SWANSON, GARTH R | reporter.nih.gov |
| Targeting a human gut bacterial genotoxin via engineered commensal bacteria | NIH | National Cancer Institute | 2025 | $627,422 | May 1, 2025 | April 30, 2030 | LI, JIAHE | reporter.nih.gov |
| Genetic variation in the metal transporter ZIP8 and impact on the innate immune response in the gut | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $625,763 | July 1, 2019 | August 31, 2024 | MELIA, JOANNA MILLER PELOQUIN | reporter.nih.gov |
| Precision therapeutics of inflammatory bowel disease guided by Boolean logic | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $621,778 | August 28, 2020 | July 31, 2023 | SAHOO, DEBASHIS | reporter.nih.gov |
| Novel Strategies for Intervention of Inflammatory Diseases and Cancer | NIH | National Cancer Institute | 2021 to 2022 | $620,730 | July 1, 2004 | May 31, 2025 | WANG, RONGFU | reporter.nih.gov |
| Phase 2 Proof-of-Concept Efficacy of BT-11 in Crohn's Disease Patients | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $613,188 | September 14, 2020 | December 15, 2023 | LICHTIGER, SIMON | reporter.nih.gov |
| Lysosome Homeostasis and Microbicidal Mechanisms in Innate Immunity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $612,953 | May 11, 2018 | February 28, 2023 | XAVIER, RAMNIK J | reporter.nih.gov |
| The Role of Macrophages in Immune Responses to Giardia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $612,377 | July 1, 2014 | July 31, 2025 | SINGER, STEVEN M | reporter.nih.gov |
| Effect of an Anti-Inflammatory Diet on Gut Homeostasis in Active and Experimental Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $610,350 | March 1, 2021 | December 31, 2025 | RAFFNER, ABIGAIL | reporter.nih.gov |
| The Intestinal Mycobiome and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $610,350 | March 1, 2021 | February 28, 2026 | DI MARTINO, LUCA | reporter.nih.gov |
| Restoring Tolerance in Inflammatory Bowel Disease with an Oral AMPK agonist Nanomedicine that Targets Antigen Presenting Cells. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $608,877 | September 20, 2024 | July 31, 2027 | CARGILL, CHRISTINA PAIGE | reporter.nih.gov |
| Bile acid-dependent T cell regulation in the intestine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $601,831 | February 6, 2019 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Decoding the functional pleiotropy of IL-20Rβ ligands in inflammation and tumorigenesis | NIH | National Cancer Institute | 2023 to 2025 | $600,696 | February 20, 2023 | January 31, 2026 | SAXTON, ROBERT ANDREW | reporter.nih.gov |
| Linking Myosin 5b and Intestinal Alkaline Phosphatase in Intestinal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $599,265 | September 15, 2025 | July 31, 2030 | ENGEVIK, AMY C | reporter.nih.gov |
| The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 | $598,178 | February 1, 2021 | January 31, 2026 | SWANSON, GARTH R | reporter.nih.gov |
| Fluorescence Lifetime Imaging (FLIm): a method to evaluate colon inflammation in vivo | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $592,575 | September 15, 2022 | April 30, 2025 | ALFONSO-GARCIA, ALBA | reporter.nih.gov |
| 3D Printed Engineered Living Materials for Drug Delivery | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2024 | $588,952 | April 5, 2022 | December 31, 2025 | NELSON, ALSHAKIM | reporter.nih.gov |
| Development of Patient-Tailored Adaptive Treatment Strategies for Acute Severe Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $582,240 | July 14, 2023 | March 31, 2028 | BERINSTEIN, JEFFREY | reporter.nih.gov |
| CD45 mediated regulation of PMN function during intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $580,568 | September 1, 2025 | June 30, 2029 | BRAZIL, JENNIFER C | reporter.nih.gov |
| Gastrointestinal Cues Influence Metabolic Control of Regulatory T cell Function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $577,280 | April 1, 2020 | February 28, 2025 | BAMIDELE, ADEBOWALE O | reporter.nih.gov |
| Assessing Predictors of Response to Anti-Tumor Necrosis Alpha Therapy in Early Crohns Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $568,026 | April 1, 2019 | June 30, 2024 | UNGARO, RYAN | reporter.nih.gov |
| Impact of AIM2 on Intestinal Stem Cell Differentiation During Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $567,205 | January 1, 2025 | November 30, 2028 | WILSON, JUSTIN ETHAN | reporter.nih.gov |
| A Fully Remote Pilot Randomized Controlled Trial to Investigate the Impact of Insomnia Treatment on Crohn’s disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $566,855 | February 15, 2023 | November 30, 2027 | SALWEN-DEREMER, JESSICA K | reporter.nih.gov |
| Precision-guided gastrointestinal therapy: a cheek-tethered capsule approach for targeted IBD disease treatment | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $556,876 | September 16, 2025 | August 31, 2028 | TERRY, BENJAMIN | reporter.nih.gov |
| Gut microbiota metabolite sensing licenses IEC to cross talk with T cells to inhibit intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $556,826 | February 15, 2023 | October 1, 2023 | CONG, YINGZI | reporter.nih.gov |
| Identifying Genomic and Microbial Contributions in Early Childhood-Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $555,984 | August 16, 2019 | May 31, 2025 | CONRAD, MAIRE ABRAHAM | reporter.nih.gov |
| Intestinal Microbial Communities and Metabolites Changes Associated with Long-term Stress Induced Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $554,874 | August 15, 2025 | July 31, 2028 | SINGH, PALLAVI | reporter.nih.gov |
| Cerium oxide nanoparticles for CT imaging and catalytic therapeutic intervention in inflammatory bowel disease | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $545,290 | January 1, 2025 | December 31, 2028 | CORMODE, DAVID PETER | reporter.nih.gov |
| Analysis of autophagy risk genes in inflammation and tissue homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $538,256 | January 1, 2013 | October 31, 2022 | XAVIER, RAMNIK J | reporter.nih.gov |
| Role of innate immunity and the microbiome in colitis associated dysplasia | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $536,536 | September 1, 2014 | April 30, 2027 | ABREU, MARIA TERESA | reporter.nih.gov |
| USING SINGLE-CELL RNA AND PROTEIN APPROACHES TO ELUCIDATE MOLECULAR DETERMINANTSAND PREDICTORS OF INFLAMMATORY BOWEL DISEASES | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $525,896 | April 1, 2020 | December 31, 2023 | BOLAND, BRIGID S | reporter.nih.gov |
| Exploring Glutamate Carboxypeptidase II (GCPII) Dysregulation in Human and Experimental IBD | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $520,560 | January 1, 2022 | December 31, 2026 | PETERS, DIANE E. | reporter.nih.gov |
| Discovery and Biological Signatures of Microbiome-Derived Xanthohumol Metabolites and their Role in Ameliorating Inflammatory Bowel Disease | NIH | National Center for Complementary & Integrative Health | 2021 | $516,964 | September 21, 2018 | August 31, 2025 | STEVENS, JAN FREDERIK | reporter.nih.gov |
| Brain-Gut biomarkers of anxiety and depressive symptoms in youth with inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $515,652 | May 1, 2020 | August 31, 2024 | REED, BONNEY | reporter.nih.gov |
| Nuclear Receptor Networks in Mucosal Immune Regulation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $511,879 | July 30, 2021 | September 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Nuclear Receptor Networks in Mucosal Immune Regulation | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $511,877 | July 30, 2021 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Machine learning-based methods for the analysis of microbial glycomes and proteomes in inflammatory bowel disease. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $508,680 | January 4, 2023 | November 30, 2027 | TAN, XIAO | reporter.nih.gov |
| Engineering Metal Ion-Immunity Crosstalk for Metalloimmunotherapy | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $507,000 | August 7, 2025 | July 31, 2030 | SUN, XIAOQI KEVIN | reporter.nih.gov |
| Inflammatory cascades disrupt Treg function through epigenetic mechanisms | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $505,712 | February 10, 2021 | January 31, 2027 | FAUBION, WILLIAM A | reporter.nih.gov |
| Precision Medicine in Inflammatory Bowel Disease: Refining the Clinical and Genomic Predictors of Response to Anti-IL-12/23 Therapy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $501,936 | April 17, 2023 | February 29, 2028 | CUSHING-DAMM, KELLY COLLEEN | reporter.nih.gov |
| Platelet-hyaluronan interactions as regulators of inflammation and thrombosis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $498,000 | August 1, 2017 | December 31, 2023 | PETREY, AARON CHRISTOPHER | reporter.nih.gov |
| Understanding the molecular mechanisms and biological functions of a novel bleach-sensing bacterial receptor in shaping host-associated bacterial populations in response to host inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $498,000 | July 16, 2020 | August 31, 2024 | BAYLINK, ARDEN | reporter.nih.gov |
| Deconstructing interactions between diet, microbiome, and immunity to gain mechanistic insight into health and disease | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $498,000 | August 1, 2022 | April 30, 2026 | ALEXANDER, MARGARET ROSE | reporter.nih.gov |
| Investigating the role of a novel fungal RNA in intestinal innate immunity and inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $498,000 | August 7, 2025 | July 31, 2030 | LI, XIN | reporter.nih.gov |
| Mechanisms of gut epithelial DUOX-mediated intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $497,721 | April 1, 2018 | January 31, 2023 | KAO, JOHN Y | reporter.nih.gov |
| CD45 mediated regulation of PMN function during intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 | $497,370 | September 16, 2024 | August 31, 2025 | BRAZIL, JENNIFER C | reporter.nih.gov |
| Elucidating the role of the microbiome in inducing gut permeability and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $491,477 | December 1, 2023 | November 30, 2026 | CHAUDHARI, SNEHAL N. | reporter.nih.gov |
| STING signaling in T cells regulation of intestinal homeostasis and inflammatorybowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 | $489,898 | May 1, 2024 | April 30, 2026 | CONG, YINGZI | reporter.nih.gov |
| Distal gut microbiome targets of host anti-proteolytic proteins during colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $488,125 | December 18, 2020 | November 30, 2022 | HANG, HOWARD C | reporter.nih.gov |
| Structure function studies in intestinal epithelial JAM | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $486,750 | May 1, 2002 | April 30, 2024 | PARKOS, CHARLES A | reporter.nih.gov |
| Dysregulation of inflammation resolution as therapeutic target for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $486,254 | July 1, 2023 | March 31, 2028 | MERIWETHER, DAVID | reporter.nih.gov |
| Optimal Preoperative Care for Older Adults with Inflammatory Bowel Disease (K76) - Resubmission - 1 | NIH | National Institute on Aging | 2024 to 2025 | $486,000 | August 15, 2024 | May 31, 2029 | FAYE, ADAM SCOTTE | reporter.nih.gov |
| Intestinal O-GlcNAc signaling and mucosal host defense | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $483,958 | September 20, 2021 | February 22, 2022 | RUAN, HAI-BIN | reporter.nih.gov |
| Determinants of bacterial biofilm formation at the intestinal mucosal interface and their roles in pathogen exclusion | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $481,125 | April 1, 2022 | March 31, 2026 | NI, JOSEPHINE | reporter.nih.gov |
| Host immunity to commensal gut fungi | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $479,837 | July 1, 2012 | May 31, 2023 | UNDERHILL, DAVID M. | reporter.nih.gov |
| Regulation of TLR signaling in anti-commensal B cell responses and mucosal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $476,575 | April 19, 2023 | March 31, 2025 | LACY-HULBERT, ADAM | reporter.nih.gov |
| Characterization of E. coli-specific T cells in Crohn's disease | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $476,075 | February 1, 2022 | January 31, 2024 | LORD, JAMES DANIEL | reporter.nih.gov |
| Signaling through intestinal MUC receptors by bacterial Serine Proteases of Enterobacteriaceae | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $474,419 | May 23, 2022 | April 30, 2025 | RUIZ, FERNANDO | reporter.nih.gov |
| The role and regulation of deep crypt secretory cells in colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $474,120 | August 15, 2022 | July 31, 2025 | SCHUMACHER, MICHAEL ANDREW | reporter.nih.gov |
| Short-Term Institutional Research Training Grant | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $473,099 | April 1, 2002 | June 30, 2029 | BLACKARD, JASON T | reporter.nih.gov |
| Bioengineering probiotic bacterium contrast agents for monitoring of inflammation using multispectral optoacoustic tomography | NIH | National Institute of Biomedical Imaging and Bioengineering | 2024 | $470,458 | March 1, 2024 | February 28, 2025 | GOMEZ-GUTIERREZ, JORGE G | reporter.nih.gov |
| Prevention of Crohns Disease in High-Risk Individuals | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $470,417 | May 1, 2024 | February 28, 2029 | LOPES, EMILY WALSH | reporter.nih.gov |
| DCs as clinical targets of anti-integrin therapy in IBD | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $470,076 | December 1, 2023 | October 31, 2026 | LORD, JAMES DANIEL | reporter.nih.gov |
| High-throughput functional analyses of the genetic drivers of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $467,200 | September 1, 2024 | June 30, 2027 | SAMUEL, BUCK SPARROW | reporter.nih.gov |
| Therapeutic targeting of PD1 signaling in inflammatory bowel disease | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $466,970 | February 3, 2023 | January 31, 2025 | GOPAL, MURUGAIYAN | reporter.nih.gov |
| Bacterial translocation to mesenteric adipose tissue drives pathogenic stromal-B cell interactions leading to inflammatory IgG | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $466,125 | February 3, 2023 | January 31, 2025 | GRASSET, EMILIE K | reporter.nih.gov |
| Commensal fungi promote wound repair by modulating host metabolites | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $465,444 | September 15, 2025 | July 31, 2030 | JAIN, UMANG | reporter.nih.gov |
| Effect of Maternal IBD, Microbiome and Early Life Events on the Bacterial Colonization and Mucosal Immunity in the Offspring | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $465,125 | August 13, 2021 | July 31, 2024 | PETER, INGA | reporter.nih.gov |
| Role of Rip2 in the Generation of Pathogenic Th17/Th1 T-cells and Ileitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $459,250 | December 7, 2020 | November 30, 2023 | CROTHER, TIMOTHY ROBERT | reporter.nih.gov |
| Extracellular Vesicles from Enterocytes are Mediators of Inflammation in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $458,047 | September 1, 2025 | August 31, 2028 | MIKLAVCIC, JOHN | reporter.nih.gov |
| Aim protein-based anti-inflammatory therapeutic for the treatment of IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $456,817 | September 19, 2023 | August 31, 2025 | POHL ROBINSON, CATHERINE | reporter.nih.gov |
| Specialization of Innate and Adaptive Immune Cells in Intestinal Barrier Function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $455,611 | March 1, 2017 | February 28, 2022 | WEAVER, CASEY T | reporter.nih.gov |
| Advanced sequencing as a novel diagnostic tool to discover strain-level variation and function of mucosal-adherent bacteria contributing to IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $451,773 | September 1, 2019 | August 31, 2024 | WANG, JEREMY R | reporter.nih.gov |
| IBD Gene Mapping by Clinical and Population Subset | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $451,377 | September 30, 2002 | July 31, 2022 | BRANT, STEVEN R | reporter.nih.gov |
| Microbiota, Tertiary Lymphoid Structures and Chronic Inflammation in the Human Gut | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $451,376 | April 6, 2021 | March 31, 2024 | BOGUNOVIC, MILENA | reporter.nih.gov |
| The Interconnection between Mouth and Gut: Understanding the Microbial and Host Factors Influencing Susceptibility to Periodontitis and Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $450,842 | September 30, 2021 | August 31, 2024 | THUMBIGERE-MATH, VIVEK | reporter.nih.gov |
| Exploring the role of a novel autoimmune disease-associated lncRNA in Treg biology | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $449,437 | November 10, 2022 | October 31, 2024 | GHOSH, SANKAR | reporter.nih.gov |
| Type 2 cytokines and innate lymphoid cells in pediatric ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $447,339 | July 18, 2018 | August 6, 2021 | ROSEN, MICHAEL J | reporter.nih.gov |
| Mast Cell G-protein Coupled Receptors in Immune Modulation of colitis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $446,875 | August 11, 2025 | July 31, 2027 | ALI, HYDAR | reporter.nih.gov |
| Type 2 cytokines and innate lymphoid cells in pediatric ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $445,952 | July 18, 2018 | May 31, 2024 | ROSEN, MICHAEL J | reporter.nih.gov |
| Vagal control of tissue SUMOylation as a novel anti-inflammatory target in IBD | NIH | National Center for Complementary & Integrative Health | 2022 to 2023 | $442,750 | July 11, 2022 | June 30, 2025 | YANG, WEI | reporter.nih.gov |
| Control of Intestinal Epithelial Function through Lymphatic-Intestinal Stem Cell Communication | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $442,493 | April 1, 2023 | February 28, 2026 | NIEC, RACHEL E | reporter.nih.gov |
| Evaluation of the SMART IBD App Digital Therapeutic Tool for Pediatric Inflammatory Bowel Disease | NIH | National Institute of Nursing Research | 2025 | $441,375 | September 3, 2025 | August 31, 2027 | HOMMEL, KEVIN | reporter.nih.gov |
| Strategy for Safe Colon-targeted Local Therapy of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $441,111 | September 22, 2021 | June 30, 2025 | TUMMALA, HEMACHAND | reporter.nih.gov |
| Investigating the role of intestinal-derived oxytocin in social behavior and gut inflammation. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $440,000 | April 1, 2024 | March 31, 2026 | BRITTON, ROBERT A | reporter.nih.gov |
| Metabolic Interactions between Salmonella and E. coli Nissle 1917 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $439,250 | July 11, 2022 | June 30, 2025 | WINTER, SEBASTIAN E | reporter.nih.gov |
| Role of cholinergic neuroimmune signaling pathway disruption in the pathogenesis of Hirschsprung-associated enterocolitis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $439,216 | July 8, 2025 | July 7, 2027 | HOTTA, RYO | reporter.nih.gov |
| The Study of Families with Heritable Crohn's Disease to Support Rational Design of Microbiodata-Based Therapies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $438,852 | January 16, 2020 | December 31, 2022 | CHEN, LEA A | reporter.nih.gov |
| Role of TRIF-Dependent TLR Signaling in Intestinal Mucosa | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $437,500 | July 1, 2012 | June 30, 2023 | TARGAN, STEPHAN R. | reporter.nih.gov |
| Genetic Regulation of Tissue Fibrosis in Human Intestinal Organoids | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $437,250 | June 15, 2021 | April 30, 2024 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Harnessing gut microbiota to reduce inflammation using broccoli-sprout diets | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $436,046 | September 1, 2022 | August 31, 2025 | PELLEGRINI, SUZANNE ISHAQ | reporter.nih.gov |
| Antioxidant regulation of intestinal homeostasis and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $435,876 | April 1, 2020 | April 19, 2023 | SHORT, SARAH PALMER | reporter.nih.gov |
| The Study of Families with Heritable Crohn's Disease to Support Rational Design of Microbiodata-Based Therapies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $435,473 | February 24, 2021 | December 31, 2025 | CHEN, LEA A | reporter.nih.gov |
| Engineered immunotherapies neutralizing interleukin-22 binding protein | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2023 | $434,847 | September 1, 2022 | June 30, 2025 | COLLIER, JOEL H | reporter.nih.gov |
| Discovery of aberrant enhancer activities during gut development that underlie genetic predisposition to pediatric Crohn's disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $431,750 | September 24, 2021 | August 31, 2024 | SETHUPATHY, PRAVEEN | reporter.nih.gov |
| TET-mediated DNA oxidations in mucosal innate defense | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $431,750 | June 7, 2022 | May 31, 2024 | ETCHEGARAY, JEAN-PIERRE | reporter.nih.gov |
| Studying the Gut-Brain inflammatory interaction | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $430,646 | July 1, 2021 | June 30, 2025 | RHEE, SANG HOON | reporter.nih.gov |
| Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $430,625 | May 17, 2022 | April 30, 2024 | COLONNA, MARCO | reporter.nih.gov |
| Nanoparticle-encapsulated Epigenetic Inhibitors for Treatment of Inflammatory Bowel Diseases | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $430,463 | February 1, 2024 | December 31, 2026 | TIAN, BING | reporter.nih.gov |
| A Comprehensive Self-Management Intervention for individuals with Inflammatory Bowel Disease | NIH | National Institute of Nursing Research | 2022 to 2024 | $430,134 | April 12, 2022 | September 30, 2025 | KAMP, KENDRA JOY | reporter.nih.gov |
| NIDDK IBD Genetics Consortium Genetic Research Center | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $429,989 | September 30, 2002 | October 31, 2023 | DUERR, RICHARD H | reporter.nih.gov |
| Defining the role of S1p and myeloid cells during enterotoxigenic B. fragilis infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $429,750 | September 22, 2021 | August 31, 2024 | DENG, ZHONG-BIN | reporter.nih.gov |
| Investigation of Human Gut-Derived Mesenchymal Stem Cells for Cellular Therapy | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $429,545 | July 17, 2024 | June 30, 2027 | CHINNADURAI, RAGHAVAN | reporter.nih.gov |
| Inflammatory Bowel Disease Susceptibility Gene Regulation of Anemia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $427,625 | March 3, 2021 | February 28, 2023 | MCCOLE, DECLAN | reporter.nih.gov |
| Novel high-throughput in vivo approach to define pathobionts driving colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $427,625 | February 13, 2021 | January 31, 2024 | ARTHUR, JANELLE C | reporter.nih.gov |
| Role of MAIT cells in a mouse model of spontaneous colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $427,625 | June 22, 2021 | May 31, 2024 | GAPIN, LAURENT | reporter.nih.gov |
| Elucidating the novel mechanism of importins in NLRP6 inflammasome regulation | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $427,625 | August 10, 2023 | July 31, 2025 | SHEN, CHEN | reporter.nih.gov |
| Understanding the role of LRRK2 G2019S-mediated gut-brain axis in the pathogenesis of Parkinson's disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $424,875 | September 15, 2022 | August 31, 2025 | KANG, ZIZHEN | reporter.nih.gov |
| Impact of developmental exposure to PFAS on the microbiota-gut-brain axis | NIH | National Institute of Environmental Health Sciences | 2023 | $423,657 | July 22, 2023 | June 30, 2025 | GAREAU, MELANIE G | reporter.nih.gov |
| The pathogenic roles of GSDMD-dependent gut epithelium extracellular vesicles in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $420,472 | April 8, 2021 | November 30, 2021 | PIZARRO, THERESA TORRES | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| University of Michigan at Ann Arbor | Ann Arbor, MI | 38 | $41.9 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 28 | $40.9 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 32 | $33.4 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 25 | $25.1 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 17 | $22.4 million | 0 | $0 |
| Washington University | Saint Louis, MO | 21 | $20.4 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 12 | $20.3 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 18 | $19.4 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 16 | $18.4 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 12 | $18.3 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 15 | $17 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 21 | $16.4 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 14 | $16.3 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 10 | $15.5 million | 0 | $0 |
| University of Louisville | Louisville, KY | 4 | $15.4 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 17 | $15.2 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 12 | $14.4 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 12 | $13.6 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 14 | $13.4 million | 0 | $0 |
| University of Chicago | Chicago, IL | 8 | $13 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 9 | $11.6 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 13 | $11.3 million | 0 | $0 |
| Yale University | New Haven, CT | 10 | $11.2 million | 0 | $0 |
| Emory University | Atlanta, GA | 10 | $10.8 million | 0 | $0 |
| Duke University | Durham, NC | 12 | $10.2 million | 0 | $0 |
| Broad Institute, Inc. | Cambridge, MA | 4 | $9.3 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 7 | $8.9 million | 0 | $0 |
| Connecticut Children's Medical Center | Hartford, CT | 2 | $8.8 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 13 | $8.1 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 7 | $8 million | 0 | $0 |
| Stanford University | Stanford, CA | 9 | $8 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 8 | $8 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 6 | $7.7 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 10 | $7.5 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 6 | $6.9 million | 0 | $0 |
| University of Texas Med BR Galveston | Galveston, TX | 8 | $6.8 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 7 | $6.6 million | 0 | $0 |
| University of California at Davis | Davis, CA | 8 | $6.5 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 7 | $6.5 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 3 | $6.3 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 6 | $5.8 million | 0 | $0 |
| University of Florida | Gainesville, FL | 10 | $5.8 million | 0 | $0 |
| University of California-Riverside | Riverside, CA | 5 | $5.8 million | 0 | $0 |
| University of South Carolina at Columbia | Columbia, SC | 4 | $5.6 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 5 | $5.5 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 5 | $5.4 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 3 | $5.3 million | 0 | $0 |
| ST. Jude Children's Research Hospital | Memphis, TN | 1 | $5.2 million | 0 | $0 |
| Rise Therapeutics, LLC | Rockville, MD | 3 | $5.1 million | 0 | $0 |
| Georgia State University | Atlanta, GA | 3 | $4.9 million | 0 | $0 |
| Dartmouth-Hitchcock Clinic | Lebanon, NH | 4 | $4.9 million | 0 | $0 |
| Benaroya Research Inst at Virginia Mason | Seattle, WA | 7 | $4.3 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 4 | $4.2 million | 0 | $0 |
| University of Nebraska Medical Center | Omaha, NE | 2 | $4.2 million | 0 | $0 |
| Feinstein Institute for Medical Research | Manhasset, NY | 1 | $3.9 million | 0 | $0 |
| Medical University of South Carolina | Charleston, SC | 7 | $3.8 million | 0 | $0 |
| Harvard Medical School | Boston, MA | 5 | $3.4 million | 0 | $0 |
| Washington State University | Pullman, WA | 3 | $3.3 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 2 | $3.2 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 2 | $3.2 million | 0 | $0 |
| Rockefeller University | New York, NY | 4 | $3 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 2 | $3 million | 0 | $0 |
| Thetis Pharmaceuticals, LLC | Deep River, CT | 1 | $3 million | 0 | $0 |
| Michigan State University | East Lansing, MI | 2 | $3 million | 0 | $0 |
| Avexegen Therapeutics, Inc. | Porter Ranch, CA | 1 | $2.9 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 1 | $2.8 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 4 | $2.7 million | 0 | $0 |
| University of Illinois at Urbana-Champaign | Urbana, IL | 1 | $2.6 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 3 | $2.5 million | 0 | $0 |
| Chromatan Corporation | Dedham, MA | 1 | $2.5 million | 0 | $0 |
| Rutgers University Newark | Newark, NJ | 3 | $2.5 million | 0 | $0 |
| University of Colorado at Boulder | Boulder, CO | 1 | $2.4 million | 0 | $0 |
| Sanford Burnham Prebys Medical Discovery Institute | La Jolla, CA | 1 | $2.4 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 8 | $2.4 million | 0 | $0 |
| Harvard University | Cambridge, MA | 4 | $2.4 million | 0 | $0 |
| University of Missouri-Columbia | Columbia, MO | 2 | $2.4 million | 0 | $0 |
| Children's Hospital of Los Angeles | Los Angeles, CA | 3 | $2.3 million | 0 | $0 |
| Vivreon Biosciences, LLC | San Diego, CA | 2 | $2.3 million | 0 | $0 |
| Epicypher, Inc. | Research Triangle Park, NC | 1 | $2.3 million | 0 | $0 |
| Aqualung Therapeutics Corp. | Juno Beach, FL | 1 | $2.2 million | 0 | $0 |
| Montreal Heart Institute | Montreal | 1 | $2.2 million | 0 | $0 |
| Oklahoma Medical Research Foundation | Oklahoma City, OK | 1 | $2.2 million | 0 | $0 |
| Ohio State University | Columbus, OH | 2 | $2.2 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 2 | $2.1 million | 0 | $0 |
| Averto Medical INC | Fremont, CA | 2 | $2.1 million | 0 | $0 |
| Sinai Health System | Toronto | 2 | $2.1 million | 0 | $0 |
| Research Inst of Fox Chase Can CTR | Philadelphia, PA | 1 | $2.1 million | 0 | $0 |
| Children's Research Institute | Washington, DC | 1 | $2.1 million | 0 | $0 |
| Fzata, Inc. | Halethorpe, MD | 1 | $2.1 million | 0 | $0 |
| Scripps Florida | Jupiter, FL | 4 | $2 million | 0 | $0 |
| Methodist Hospital Research Institute | Houston, TX | 1 | $2 million | 0 | $0 |
| SUNY at Stony Brook | Stony Brook, NY | 4 | $2 million | 0 | $0 |
| Aviara Pharmaceuticals, Inc. | Houston, TX | 1 | $2 million | 0 | $0 |
| Altis Biosystems, Inc. | Durham, NC | 1 | $2 million | 0 | $0 |
| Fistula Solution Corporation | Scandia, MN | 1 | $1.9 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 2 | $1.9 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 2 | $1.9 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 2 | $1.8 million | 0 | $0 |
| Cornell University | Ithaca, NY | 2 | $1.7 million | 0 | $0 |
| Pennsylvania State Univ University Park | University Park, PA | 2 | $1.7 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 355 | $177,547,971 | 0 | $0 |
| 2024 | 361 | $159,825,190 | 0 | $0 |
| 2023 | 385 | $174,660,609 | 0 | $0 |
| 2022 | 384 | $158,814,532 | 0 | $0 |
| 2021 | 374 | $150,931,210 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.