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Data / Research funding / Human Embryonic Stem Cell Research

Human Embryonic Stem Cell Research: 448 NIH awards ($869.6M) to 131 organizations

448 NIH awards ($869.6M) in the NIH spending category Human Embryonic Stem Cell Research, to 131 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

448 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Washington National Primate Research CenterNIHOffice of the Director, National Institutes of Health2021 to 2025$66,616,318June 10, 1997April 30, 2027OSTENDORF, MARIreporter.nih.gov
RADX BLUEPRINT MEDTECH TRANSLATOR COHORT 2 - COMMERCIALIZATION CENTER - HEALNIHNational Heart, Lung, and Blood Institute2022 to 2025$27,543,152June 2, 2025June 1, 2026reporter.nih.gov
SCREENING OF INVESTIGATIONAL THERAPEUTICS TO TREAT, MODIFY OR PREVENT EPILEPSY FOR THE NINDS EPILEPSY THERAPY SCREENING PROGRAM (ETSP)NIHNational Institute on Drug Abuse2022 to 2025$20,858,598March 23, 2022December 31, 2025WILCOX, KARENreporter.nih.gov
Replication Study of Off-Target Assays for Guide RNAs in CRISPR-Based TherapeuticsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$17,077,732December 1, 2024April 30, 2025SAHA, KRISHANUreporter.nih.gov
Center for Live Cell GenomicsNIHNational Human Genome Research Institute2021 to 2025$11,992,289September 15, 2021June 30, 2027HAUSSLER, DAVID Hreporter.nih.gov
Revealing the single cell determinants of brain relevant to persistent HIV infection and opioid use disorderNIHNational Institute on Drug Abuse2021 to 2025$11,197,081September 30, 2021July 31, 2027RANA, TARIQ Mreporter.nih.gov
Multiscale functional characterization of genomic variation in human developmental disordersNIHNational Human Genome Research Institute2021 to 2025$8,736,987September 1, 2021May 31, 2027HON, GARY CHUNGreporter.nih.gov
Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systemsNIHNational Human Genome Research Institute2021 to 2025$8,077,896September 1, 2021May 31, 2027SHENDURE, JAY ASHOKreporter.nih.gov
Reexamining the Role of Dendrites in Neuronal FunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,740,604August 1, 2023July 31, 2028YUSTE, RAFAELreporter.nih.gov
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primatesNIHNational Institute on Drug Abuse2023 to 2025$7,434,979June 1, 2023February 29, 2028RANA, TARIQ Mreporter.nih.gov
Application of Progenitor Niche Signals to Ex Vivo NephrogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,389,413September 15, 2021June 30, 2027OXBURGH, LEIFreporter.nih.gov
Center for scalable knockout and multimodal phenotyping in genetically diverse human genomesNIHNational Human Genome Research Institute2022 to 2025$7,316,442August 15, 2022May 31, 2027HUANGFU, DANWEIreporter.nih.gov
Genomic control of gene regulatory networks governing early human lineage decisionsNIHNational Human Genome Research Institute2021 to 2025$7,036,239August 19, 2021May 31, 2026HUANGFU, DANWEIreporter.nih.gov
The impact of genomic variation on environment-induced changes in pancreatic beta cell statesNIHNational Human Genome Research Institute2021 to 2025$6,348,795September 7, 2021May 31, 2027CARTER, HANNAH KATHRYNreporter.nih.gov
Molecular Mechanisms of Pathogenesis in Huntington’s diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,238,150May 1, 2020April 30, 2028THOMPSON, LESLIE MICHELSreporter.nih.gov
Design of Precision Small Molecules Targeting RNA Repeating Transcripts to Manipulate and Study Disease BiologyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,233,749May 1, 2020April 30, 2028DISNEY, MATTHEW Dreporter.nih.gov
Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomicsNIHNational Human Genome Research Institute2021 to 2025$6,001,599September 1, 2021May 31, 2026WU, HAOreporter.nih.gov
Accelerating photoreceptor replacement therapy with in-vivo cellular imaging of retinal functionNIHNational Eye Institute2021 to 2025$5,733,511September 30, 2021January 31, 2027MCGREGOR, JULIETTE ELIZABETHreporter.nih.gov
Molecular Biology Across Scales Training ProgramNIHNational Institute of General Medical Sciences2023 to 2025$5,468,885July 1, 2023June 30, 2028BILDER, DAVIDreporter.nih.gov
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,391,456June 1, 2019May 31, 2027JAFFREY, SAMIE Rreporter.nih.gov
Mechanisms of neurodegenerative diseases: intersections with ubiquitin pathwaysNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,356,529May 1, 2021April 30, 2029PAULSON, HENRY Lreporter.nih.gov
Molecular Pathogenesis of Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$4,591,274August 13, 2015June 30, 2029LEY, TIMOTHY J.reporter.nih.gov
Pathological Mechanisms of Human Cerebellar MalformationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,519,501September 1, 2016June 30, 2028MILLEN, KATHLEEN JOYCEreporter.nih.gov
Functional Analysis of Epigenetic ComplexesNIHNational Institute of General Medical Sciences2021 to 2025$4,411,981April 1, 2019February 28, 2029KINGSTON, ROBERTreporter.nih.gov
Understanding the role of metabolism in cancerNIHNational Cancer Institute2021 to 2025$4,148,510September 10, 2019August 31, 2026VANDER HEIDEN, MATTHEW G.reporter.nih.gov
Regulation of mRNA processing: Mechanisms and ConsequencesNIHNational Institute of General Medical Sciences2021 to 2025$3,993,090June 8, 2016May 31, 2026MANLEY, JAMES L.reporter.nih.gov
Interrogating Complex Methylome Network with Integrated Chemical Biology ToolsNIHNational Institute of General Medical Sciences2021 to 2025$3,968,800June 1, 2019May 31, 2029LUO, MINKUIreporter.nih.gov
Multifunctional morphogens: patterning precision and mesoderm migrationNIHNational Institute of General Medical Sciences2021 to 2025$3,886,095July 1, 2020August 31, 2029HEEMSKERK, IDSE JOANNESreporter.nih.gov
Harnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,810,605February 1, 2021January 31, 2028GUNDRY, REBEKAH L.reporter.nih.gov
Genomic and functional characterization of ASD and ID-associated MYT1L mutationNIHNational Institute of Mental Health2021 to 2025$3,747,342December 1, 2020October 31, 2026KROLL, KRISTEN Lreporter.nih.gov
Latrophilin Function in Synapse FormationNIHNational Institute of Mental Health2021 to 2025$3,624,291July 1, 2021April 30, 2026SUDHOF, THOMAS C.reporter.nih.gov
DNA transposons and alternative pre-mRNA splicing.NIHNational Institute of General Medical Sciences2021 to 2025$3,562,349June 15, 2016May 31, 2027RIO, DONALD Creporter.nih.gov
Biochemical and cellular mechanisms linking actin mutations to visceral myopathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,487,348September 28, 2021August 31, 2027HEUCKEROTH, ROBERT Oreporter.nih.gov
Defining mechanisms of disease and repair in a viral model of multiple sclerosisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,467,101May 1, 2020April 30, 2029LANE, THOMAS Ereporter.nih.gov
Unraveling yellow fever 17D vaccine attenuation: The role of type I interferon and innate immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,421,854February 15, 2016July 31, 2027RICE, CHARLES Mreporter.nih.gov
Nanoscale probes for sensing molecular functions in live cellsNIHNational Institute of General Medical Sciences2021 to 2025$3,364,334June 1, 2021May 31, 2027CUI, BIANXIAOreporter.nih.gov
Role of Energy Metabolism in Patterning the Vertebrate Musculo-Skeletal AxisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,337,554March 1, 2016March 31, 2026POURQUIE, OLIVIERreporter.nih.gov
Engineering synthetic immune cells with modular sentinel and therapeutic functions for T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,328,254April 1, 2022September 30, 2026LIM, WENDELL Areporter.nih.gov
The Primate Corticospinal Connectome and TranscriptomeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,321,910September 15, 2017May 31, 2026TUSZYNSKI, MARK H.reporter.nih.gov
Versatile, exponentially scalable methods for single cell molecular profilingNIHNational Human Genome Research Institute2021 to 2025$3,289,666September 15, 2019April 30, 2028SHENDURE, JAY ASHOKreporter.nih.gov
Design, prediction, and prioritization of systematic perturbations of the human genomeNIHNational Human Genome Research Institute2021 to 2025$3,243,707September 1, 2021May 31, 2027ALLEN, ANDREW Sreporter.nih.gov
Genetic and Structural Basis for Virus Neutralization of ParamyxovirusesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,230,785September 16, 2024September 15, 2027reporter.nih.gov
Reprogramming and Directed Differentiation of Skeletal Muscle Cells from hPSCsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,204,262September 20, 2013June 30, 2028PYLE, APRIL Dreporter.nih.gov
Directing Fate, Subtype Identity and Survival in Human Pluripotent-Derived Midbrain Dopamine NeuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,203,281April 1, 2021March 31, 2027STUDER, LORENZ P.reporter.nih.gov
Mechanism of chromatin accessibility, 3D chromosome organization, and their functions in gene regulationNIHNational Institute of General Medical Sciences2021 to 2025$3,190,319January 1, 2021December 31, 2026BAI, LUreporter.nih.gov
Developing preclinical xenograft models in zebrafish.NIHOffice of the Director, National Institutes of Health2022 to 2025$3,178,512March 1, 2022February 28, 2026LANGENAU, DAVID MICHAELreporter.nih.gov
Microphysiological Model of Human Cardiac Sympathetic InnervationNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,165,021July 1, 2022June 30, 2027KIM, DEOK-HOreporter.nih.gov
Harnessing Novel Human Endocrine Progenitor Biology for Enhanced Generation of Beta Cells from Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,140,632September 1, 2025August 31, 2029SNEDDON, JULIE BETHreporter.nih.gov
A DUAL CHIMERIC HUMAN ASTROGLIAL-MICROGLIAL MODEL OF HIV AND HANDNIHNational Institute on Drug Abuse2021 to 2025$3,125,946August 1, 2021May 31, 2026GOLDMAN, STEVEN ALANreporter.nih.gov
Neuronal Autophagy: a Cell-Autonomous Protection MechanismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,106,444April 1, 2008January 31, 2028YUE, ZHENYUreporter.nih.gov
Mechanisms and Function of Myonuclear PositioningNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,074,996September 1, 2014January 31, 2027BAYLIES, MARY Kreporter.nih.gov
Assessing Genomic, Regulatory and Transcriptional Variation at Single Nuclei Resolution in the Brains of Individuals with Autism Spectrum DisorderNIHNational Institute of Mental Health2021 to 2025$3,034,663July 27, 2021May 31, 2027NOWAKOWSKI, TOMASZreporter.nih.gov
Modeling Inner Ear Differentiation with Pluripotent Stem CellsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,024,653March 1, 2014May 31, 2029HASHINO, ERIreporter.nih.gov
Development of ultra-efficient antibodies for single cell mapping applicationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,018,104March 10, 2023February 28, 2026JOHNSTONE, ANDREA LYNNreporter.nih.gov
Engineering multi-lineage inner ear organoidsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,010,274December 1, 2018June 30, 2025KOEHLER, KARL RUSSELLreporter.nih.gov
Cell-Type Specific Mechanisms of Mitral Valve ProlapseNIHNational Heart, Lung, and Blood Institute2025$3,008,247September 1, 2025August 31, 2029CHI, NEIL Creporter.nih.gov
Unraveling the Genetic Programs Engaged in ASD Neurons Through Coupled Transcriptomic and Phenotypic ReadoutsNIHNational Institute of Mental Health2022 to 2025$2,986,134August 10, 2022June 30, 2027FARHI, SAMOUILreporter.nih.gov
Specialized Translational Control of Stem Cell Differentiation and Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,979,836March 15, 2016March 31, 2026BARNA, MARIAreporter.nih.gov
Integration and functionality of retinal organoid transplantsNIHNational Eye Institute2021 to 2025$2,971,351May 1, 2021March 31, 2027SEILER, MAGDALENE Jreporter.nih.gov
Developmental programming of adult stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,970,076September 15, 2025September 14, 2029MANA, MIYEKOreporter.nih.gov
RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,911,488July 1, 2022June 30, 2027HEITMAN, JOSEPHreporter.nih.gov
iSTAR TregsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,906,574July 1, 2023June 30, 2027TANG, QIZHIreporter.nih.gov
Elucidating the molecular mechanisms behind human neurodevelopmental disorders using brain organoidsNIHNational Institute of Mental Health2022 to 2025$2,876,812February 16, 2022December 31, 2026NOVITCH, BENNETT Greporter.nih.gov
Functional mapping of noncoding regulatory variants in human neuronal subtypes3.NIHNational Institute of Mental Health2022 to 2025$2,846,517March 18, 2022January 31, 2027YANG, NANreporter.nih.gov
Regulation of protein multi-functionality by 3 UTRsNIHNational Institute of General Medical Sciences2022 to 2025$2,832,000February 14, 2022December 31, 2026MAYR, CHRISTINEreporter.nih.gov
Role of VZV Latency Transcript (VLT) and ORF63 in latency and reactivationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,825,270November 17, 2020October 31, 2026KINCHINGTON, PAUL R.reporter.nih.gov
Cell-Type Specific Mechanisms of HIV CardiomyopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,817,007December 6, 2021November 30, 2025CHI, NEIL Creporter.nih.gov
Multimarker surface signatures of human islet derived extracellular vesiclesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,815,725September 22, 2022May 31, 2027ROUTENBERG, DAVID AARONreporter.nih.gov
Chromatin Dynamics During Epithelial CommitmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,805,406September 1, 2024June 30, 2029ORO, ANTHONY Ereporter.nih.gov
Defining the role of MafA in islet beta cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,772,028July 29, 2011May 31, 2027STEIN, ROLAND Wreporter.nih.gov
TMPRSS2 as a potential target for treatments of COVID-19 and respiratory infectious viruses in lungNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,759,863September 1, 2022August 31, 2026CHEN, YA-WENreporter.nih.gov
Robust mapping of chromatin loops from sparse or single cell Hi-C data with DeepLoopNIHNational Human Genome Research Institute2021 to 2025$2,742,397August 3, 2017May 31, 2027JIN, FULAIreporter.nih.gov
Modeling ASD-linked genetic mutations in 3D human brain organoidsNIHNational Institute of Mental Health2021 to 2025$2,714,855February 1, 2018June 30, 2029ARLOTTA, PAOLAreporter.nih.gov
Regulation of DNA methylation by TETs and QSER1NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,694,857September 22, 2022August 31, 2027EVANS, TODD Rreporter.nih.gov
Kidney Injury Molecule-1 in Epithelial RepairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,678,187June 1, 2005June 30, 2027BONVENTRE, JOSEPH VINCENTreporter.nih.gov
Mechanisms of neuromuscular degeneration in SBMANIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,675,706September 1, 2021May 31, 2027LIEBERMAN, ANDREW Preporter.nih.gov
NSR-GENE (Neonatal Seizure Registry, GEnetics of post-Neonatal Epilepsy)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,671,951March 1, 2022February 28, 2027GLASS, HANNAH CRANLEYreporter.nih.gov
Engineering High-Fidelity Human Cochlear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,639,492July 1, 2022June 30, 2027HASHINO, ERIreporter.nih.gov
A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human CerebellumNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,630,611April 15, 2022March 31, 2027MILLEN, KATHLEEN JOYCEreporter.nih.gov
Disease Mechanisms of Pontocerebellar Hypoplasia Type 10NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,628,742July 1, 2021March 17, 2026SCHAFFER, ASHLEIGH Ereporter.nih.gov
Biomechanical Forces and the Enteric Nervous System: Advancing the Development and Function of Tissue-Engineered IntestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,618,975September 8, 2025September 7, 2029SPEER, ALLISON LEIGHreporter.nih.gov
Mechanisms of Disease and Treatment in Novel Metabolic Developmental Brain DisordersNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,618,366December 1, 2021November 30, 2026MORROW, ERIC Mreporter.nih.gov
Single Cell Tracking of 3D Epigenetic Landscape Evolution During Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,584,586March 1, 2022February 28, 2027ZHONG, SHENGreporter.nih.gov
VZV vaccine attenuation and the DNA damage responseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,569,364July 1, 2022June 30, 2027KINCHINGTON, PAUL R.reporter.nih.gov
Modeling Normal and Abnormal TrophoblastsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,565,353September 25, 2018March 31, 2028SCHULZ, LAURA CLAMONreporter.nih.gov
Mechanisms underlying extracellular vesicle mediated changes in inflammation, neural circuitry and plasticity following cortical injury in aged monkeysNIHNational Institute on Aging2022 to 2025$2,553,369July 15, 2022June 30, 2027MOORE, TARA Lreporter.nih.gov
Dissecting mechanistic links between MAPK signaling, genomic hypomethylation and naive pluripotencyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,552,730April 1, 2021March 31, 2026HOCHEDLINGER, KONRADreporter.nih.gov
Nuclear Organization and FunctionNIHNational Institute of General Medical Sciences2021 to 2025$2,547,385February 1, 2021January 31, 2027CORCES, VICTOR G.reporter.nih.gov
Tracking SARS-CoV-2 one molecule at a time: Spatiotemporal investigation of coronavirus replication dynamics and host response in single cells in vitro and in vivoNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,516,194February 11, 2022January 31, 2027RICE, CHARLES Mreporter.nih.gov
Deciphering Principles of Human Embryonic Patterning in Development and DiseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,512,500September 15, 2022August 31, 2027SOZEN, BERNAreporter.nih.gov
Cross-regulation between loop extrusion, chromatin fiber structure and chromatin-associated RNAsNIHNational Institute of General Medical Sciences2022 to 2025$2,502,041September 1, 2022August 31, 2027RISCA, VIVIANA Ireporter.nih.gov
Administrative supplement for Intersection of signaling pathways and transcription factors regulating islet developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,494,396July 1, 2018December 31, 2027GADUE, PAUL Jreporter.nih.gov
Development of anti-inflammatory nanodrug for endometriosis treatmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,492,373September 30, 2022June 30, 2027KIM, TAEHOreporter.nih.gov
A clear view of encephalitis: a single cell approach to determine the basis of flaviviral pathogenesis in the central nervous systemNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,486,737January 21, 2022December 31, 2026RICE, CHARLES Mreporter.nih.gov
Molecular Interactions during Neural Crest FormationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,429,629August 1, 2007July 31, 2026GARCIA-CASTRO, MARTIN I.reporter.nih.gov
Genipin’s ECM Crosslinking Action as an Agent to Prevent Neurodegeneration in Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,424,350April 1, 2021June 30, 2030ZELTNER, NADJAreporter.nih.gov
Molecular Genetics of the Telomere Biology DisordersNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,421,352May 15, 2016June 30, 2026BERTUCH, ALISON Areporter.nih.gov
Integration of Feeding Time and Glucose Metabolism by the Circadian Gene NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,412,877September 17, 2021June 30, 2027BASS, JOSEPHreporter.nih.gov
Immunoevasive Engineered Living Blood VesselsNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,412,484August 5, 2022April 30, 2027CHAIKOF, ELLIOTreporter.nih.gov
Ubiquitin‐mediated proteolysis and cell cycle controlNIHNational Institute on Aging2021 to 2025$2,411,734April 1, 1997April 30, 2028HARPER, JEFFREY Wreporter.nih.gov
Roles of Gsx factors in basal ganglia developmentNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,397,818January 1, 2022December 31, 2026CAMPBELL, KENNETH Jreporter.nih.gov
Regulation of pancreatic islet cell fateNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,361,366August 1, 2009July 31, 2027SUSSEL, LORIreporter.nih.gov
Understanding the variation of induced β-cell differentiation.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,351,360July 1, 2022June 30, 2027LI, YANreporter.nih.gov
Gene regulatory network modeling of disease-associated DNA methylation perturbationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,350,364June 1, 2023May 31, 2028MIRALDI, EMILYreporter.nih.gov
Islet-specific CD8 T cells in the pathogenesis of type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,344,031August 20, 2013May 31, 2030NAKAYAMA, MAKIreporter.nih.gov
Retinal sheet transplant impact on functional organization of visual cortex in retinal degenerate animal modelsNIHNational Eye Institute2022 to 2025$2,340,862May 1, 2022March 31, 2027LYON, DAVID Creporter.nih.gov
Harnessing the chromatin conformational code for epigenetic regulationNIHNational Institute of General Medical Sciences2022 to 2025$2,340,600September 1, 2022August 31, 2027SANULLI, SERENAreporter.nih.gov
Mechanistic studies of the genetic contribution of desmoplakin to pulmonary fibrosis in alveolar type 2 cellsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,340,458August 15, 2023July 31, 2027WILSON, ANDREW Areporter.nih.gov
The Synthetic Kidney: A Revolutionary Solution for the Shortage of Kidneys for TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,335,138September 15, 2022August 31, 2027LI, ZHONGWEIreporter.nih.gov
Cell Fate Regulation in Esophageal Progenitor CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,322,436April 1, 2022March 31, 2027QUE, JIANWENreporter.nih.gov
Interdisciplinary approaches for understanding how arsenic and micronutrients affect the epigenome to influence spina bifida riskNIHNational Institute of Environmental Health Sciences2023 to 2025$2,321,700January 20, 2023December 31, 2026MAZUMDAR, MAITREYIreporter.nih.gov
Regulating Gli Function in Hair Follicle ProgenitorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,320,049May 7, 2007December 31, 2027ORO, ANTHONY Ereporter.nih.gov
TMEM41B: a pan-flavivirus and pan-coronavirus host factor with antiviral potentialNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,286,496September 19, 2022July 31, 2027RICE, CHARLES Mreporter.nih.gov
Towards Robust Multiplex Genome Engineering Beyond CRISPR-Cas9NIHNational Human Genome Research Institute2021 to 2025$2,286,025September 1, 2020May 31, 2026CONG, LEreporter.nih.gov
The role of EZH1 in neuronal differentiation and neurological disordersNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,282,077May 5, 2022April 30, 2027AKIZU, NAIARAreporter.nih.gov
The selective advantage of mismatch repair loss in colonic stem cellsNIHNational Cancer Institute2021 to 2025$2,253,508April 1, 2021March 31, 2027HEINEN, CHRISTOPHER D.reporter.nih.gov
Regulation of Dynein-Mediated TransportNIHNational Institute of General Medical Sciences2021 to 2025$2,248,827July 15, 2021May 31, 2026MARKUS, STEVEN Mreporter.nih.gov
The role of CELF2 and its genetic variants in Alzheimer's diseaseNIHNational Institute on Aging2021 to 2025$2,244,593February 1, 2021January 31, 2027CHEN, LIZHENreporter.nih.gov
Oxylipin Signaling in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,228,649January 1, 2021November 30, 2026AGUIRRE, AITORreporter.nih.gov
Genomic and Physiological Impact of Transposable Elements.NIHNational Institute of General Medical Sciences2021 to 2025$2,219,758September 8, 2017March 31, 2028FESCHOTTE, CEDRICreporter.nih.gov
Neutrophil migration and inflammationNIHNational Institute of General Medical Sciences2021 to 2025$2,206,886August 11, 2016July 31, 2027DENG, QINGreporter.nih.gov
Developmentally Regulated Enhancers and Chromatin Architecture in Human NeurogenesisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,149,369August 15, 2022May 31, 2027PLACANTONAKIS, DIMITRIS G.reporter.nih.gov
Retinoid Metabolism in the Adult Heart and Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,140,517April 1, 2023March 31, 2027FOSTER, D BRIANreporter.nih.gov
Understanding Genetic Complexity in Spina BifidaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,136,543September 12, 2023August 31, 2028ROSS, MARGARET ELIZABETHreporter.nih.gov
Endolysosomal Proteome Landscapes Through the Lens of Neurodegenerative Risk AllelesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,131,982September 19, 2024August 31, 2029HARPER, JEFFREY Wreporter.nih.gov
Functional interaction of transcriptional regulators in endocrine lineage specificationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,125,269January 1, 2023December 31, 2027STOFFERS, DORIS Areporter.nih.gov
Regulation of synaptic plasticity by BDNF-endocannabinoid interactionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,110,192December 1, 2019November 30, 2026LEVINE, ERIC Sreporter.nih.gov
Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,109,517August 21, 2023June 30, 2028CHEN, SHUIBINGreporter.nih.gov
Local immune modulation for beta cell replacement therapy in type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,091,787April 1, 2022December 31, 2026PHELPS, EDWARDreporter.nih.gov
DEFINING REGULATORY ROLES FOR HISTONE H3 METHYLATION IN DEVELOPMENTNIHNational Institute of General Medical Sciences2021 to 2025$2,087,570July 15, 2021March 31, 2027BRUMBAUGH, JUSTINreporter.nih.gov
Structure and Functionof Nanog in Stem Cell PluripotencyNIHNational Institute of General Medical Sciences2021 to 2025$2,086,645January 1, 2018May 31, 2027FERREON, JOSEPHINE CHUreporter.nih.gov
Comprehensive characterization of HNF1A-driven beta-cell heterogeneityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,080,892July 1, 2018June 30, 2028LI, YANreporter.nih.gov
Myovascular Mechanisms of Cardiac Growth and RegenerationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,080,009January 1, 2022December 31, 2026KARRA, RAVIreporter.nih.gov
Assembly of Novel Gene Editing Particles to Understand Genome Surgery in Patient-Derived CellsNIHNational Institute of General Medical Sciences2021 to 2025$2,078,314August 19, 2016May 31, 2026SAHA, KRISHANUreporter.nih.gov
Human gene duplications in neurodevelopment and diseaseNIHNational Institute of Mental Health2025$2,075,532September 20, 2023July 31, 2028DENNIS, MEGAN Yreporter.nih.gov
Human iPSC-Based Personalized Cell Therapy of PDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,062,628July 1, 2023April 30, 2028KIM, KWANG-SOOreporter.nih.gov
Epigenetic Maintenance of Neural Cell IdentityNIHNational Institute of Mental Health2021 to 2025$2,062,500August 10, 2021May 31, 2026BELL, OLIVERreporter.nih.gov
Molecular regulators of human amniogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,055,093September 16, 2019May 31, 2029TANIGUCHI, KENICHIROreporter.nih.gov
Dissect Human Primordial Germ Cell Development Using Stem Cell ModelsNIHNational Institute of General Medical Sciences2025$2,043,430September 1, 2025August 31, 2029ZHENG, YIreporter.nih.gov
Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical InjuriesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,031,527July 1, 2021June 30, 2027CHEN, HAN-CHIAO ISAACreporter.nih.gov
Establishing a human cellular model of retinal ganglion cell compartmentalization in neurodegeneration and neuroinflammationNIHNational Eye Institute2021 to 2025$2,011,938September 1, 2021August 31, 2027MEYER, JASON STEPHENreporter.nih.gov
Role of microglia in neural infectionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,997,135January 15, 2022December 31, 2026WU, PINGreporter.nih.gov
Transcriptional Regulation of Endothelial Cells after Neonatal Lung InjuryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,984,340April 1, 2018June 30, 2027KALINICHENKO, VLADIMIRreporter.nih.gov
Embryonic Stem Cell Therapy after Cervical Contusion SCI in NHPsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,982,569February 1, 2023January 31, 2028ROSENZWEIG, EPHRON SOLOMONreporter.nih.gov
Frontiers in Emerging, Reemerging and Zoonotic Diseases and Diversity (FrERZD2)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,977,995September 1, 2021August 31, 2026SCHATTEN, GERALDreporter.nih.gov
The molecular basis of IMiD induced neo-substrate recruitment to the CRL4CRBN ubiquitin E3 ligaseNIHNational Cancer Institute2021 to 2025$1,973,693March 1, 2017March 31, 2027FISCHER, ERIC SEBASTIANreporter.nih.gov
Human Dopamine Grafts in Alpha-Synuclein Models of Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,967,447July 1, 2023June 30, 2028TABAR, VIVIANEreporter.nih.gov
Roles for uniquely human enhancers in brain development and WNT signalingNIHNational Institute of Mental Health2023 to 2025$1,966,795March 9, 2023December 31, 2027SILVER, DEBRA L.reporter.nih.gov
Novel Therapeutics for Timothy Syndrome and Related Cardiac ChannelopathyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,964,096September 1, 2023May 31, 2027YAZAWA, MASAYUKIreporter.nih.gov
Engineering multifaceted 3D human organ platforms for toxicity testingNIHNational Institute of General Medical Sciences2021 to 2025$1,962,500September 24, 2021July 31, 2026KOPPES, RYAN ALANreporter.nih.gov
Trophoblast progenitor heterogeneity and function in normal and Trisomy 21-affected placentaeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,959,382September 20, 2023June 30, 2028PARAST, MANA Mreporter.nih.gov
Vascular Regeneration with Human Pluripotent Stem Cell-derived Vascular Cells and Engineering ApproachesNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,956,185January 15, 2022December 31, 2025YOON, YOUNG-SUPreporter.nih.gov
Biology of RNA damage and repairNIHNational Institute of General Medical Sciences2021 to 2025$1,947,425August 1, 2016May 31, 2026HESSELBERTH, JAY Rreporter.nih.gov
Cell Intrinsic and Extrinsic Factors Driving Maturation in Human PSC-derived NeuronsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,946,321August 1, 2023July 31, 2028STUDER, LORENZ P.reporter.nih.gov
Employing viruses to unravel the functional significance of the m5C epitranscriptomeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,938,825February 7, 2023January 31, 2028RICE, CHARLES Mreporter.nih.gov
Probing the Role of Integrator in Neuronal FunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,933,889September 20, 2023July 31, 2028WAGNER, ERIC Jreporter.nih.gov
Uncover Spatial-Constraint Related Morphome Using Tissue-on-a-Chip Platform and Data-Driven Mathematical ModelingNIHNational Institute of General Medical Sciences2021 to 2025$1,932,445September 1, 2021August 31, 2027HUANG, YUreporter.nih.gov
Uncovering fundamentals of gene regulation by enhancersNIHNational Institute of General Medical Sciences2021 to 2025$1,931,186May 15, 2019March 31, 2029WYSOCKA, JOANNAreporter.nih.gov
Molecular Genetics of a Complement Factor H homologNIHNational Eye Institute2021 to 2025$1,919,663September 30, 2021July 31, 2026VOGEL, BRUCE Ereporter.nih.gov
Transposable Element Interaction and Its Impact on Human Development and HealthNIHOffice of the Director, National Institutes of Health2022 to 2025$1,909,873September 15, 2022August 31, 2027XIA, BOreporter.nih.gov
Multi-organism platform for functional assessment of human birth defect associated genomic variantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,906,531December 20, 2022November 30, 2027SOLNICAKREZEL, LILIANNAreporter.nih.gov
Molecular Principles Governing Mitochondrial and Peroxisomal Remodeling as Drivers of Cell Fate and IdentityNIHNational Institute of General Medical Sciences2021 to 2025$1,889,532August 1, 2018July 31, 2029GAMA, VIVIANreporter.nih.gov
Mismatch Repair and CarcinogenesisNIHNational Cancer Institute2021 to 2025$1,880,282April 1, 1995June 30, 2027FISHEL, RICHARDreporter.nih.gov
An Integrated Drug Discovery Platform for Neurodevelopmental Disorders Using Standardized Self-Organizing Human CerebroidsNIHNational Institute of Mental Health2024 to 2025$1,879,800May 1, 2024April 30, 2027ETOC, FREDreporter.nih.gov
Altered inflammatory response associated with acquired DNMT3A mutationsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,875,949May 1, 2021April 30, 2027BYUN, MINJIreporter.nih.gov
Elucidating the origins of cortical tuber cells using human brain organoid models of TSCNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,875,828May 15, 2016February 28, 2026BATEUP, HELEN S.reporter.nih.gov
Measuring and modeling the dynamics ofpatterning in human stem cellsNIHNational Institute of General Medical Sciences2021 to 2025$1,875,174January 11, 2019July 31, 2027RAMANATHAN, SHARADreporter.nih.gov
Chromatin Domain Structure and FunctionNIHNational Institute of General Medical Sciences2021 to 2025$1,873,407February 1, 1999April 30, 2027BELMONT, ANDREW STEVENreporter.nih.gov
Determinants of Cell State ReprogrammingNIHNational Institute of General Medical Sciences2022 to 2025$1,850,032June 1, 2022May 31, 2027HON, GARY CHUNGreporter.nih.gov
Targeting Endosomal dysfunction as a new source of biomarkers for Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$1,825,240March 15, 2022December 31, 2026ALVES SIMOES SPASSOV, SABRINAreporter.nih.gov
Sequence-based Machine Learning for Inference of Dynamic Cell State Gene Network ModelsNIHNational Human Genome Research Institute2022 to 2025$1,820,976July 15, 2022April 30, 2027BEER, MICHAEL Areporter.nih.gov
Investigation of UBQLN2 in neuronal dysfunction and ALS-FTDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,803,720June 15, 2023May 31, 2028WHITELEY, ALEXANDRAreporter.nih.gov
Mechanisms of Mammalian Genetic Hearing LossNIHNational Institute on Deafness and Other Communication Disorders2023 to 2025$1,793,239April 1, 2023March 31, 2028NELSON, RICK Freporter.nih.gov
Studying the Role of the Microenvironment on Differentiation and Maturation of Beta CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,778,223July 1, 2017May 31, 2027MILLMAN, JEFFREY ROBERTreporter.nih.gov
Coordination of alternative exon and 3'UTR choices in mRNAsNIHNational Institute of General Medical Sciences2022 to 2025$1,755,648July 1, 2020March 31, 2030MIURA, PEDROreporter.nih.gov
Pluripotent stem cell-derived organoid model of human gonad development, functions, and disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,746,338September 18, 2023August 31, 2027JORDAN, PHILIP Wreporter.nih.gov
Non-B DNA and Genome EvolutionNIHNational Institute of General Medical Sciences2024 to 2025$1,735,219January 1, 2024December 31, 2028MAKOVA, KATERYNAreporter.nih.gov
Immunology & Molecular Medicine Program Training GrantNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,734,172July 1, 2012July 31, 2029ROBEY, ELLEN Areporter.nih.gov
Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and PathogenesisNIHNational Institute on Aging2024 to 2025$1,714,215December 1, 2023November 30, 2028HUANG, TIMOTHY YIKAIreporter.nih.gov
Regulatory roles of the epitranscriptome and RNA structurome during vertebrate developmentNIHNational Institute of General Medical Sciences2022 to 2025$1,713,831August 1, 2022July 31, 2027BEAUDOIN, JEAN-DENISreporter.nih.gov
AI-designed mini-proteins as drivers of pancreatic islet production from pluripotent stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$1,712,270September 25, 2025July 31, 2030CIRULLI, VINCENZINOreporter.nih.gov
Dissect formative pluripotency using cultured pluripotent stem cellsNIHNational Institute of General Medical Sciences2021 to 2025$1,702,655July 22, 2021May 31, 2026WU, JUNreporter.nih.gov
Human‐specific vulnerabilities and compensatory adaptations to age‐related stressors in selectively vulnerable midbrain dopaminergic neuronsNIHNational Institute on Aging2024 to 2025$1,682,833August 15, 2024July 31, 2029POLLEN, ALEXANDER Areporter.nih.gov
Articular Cartilage Tissue Engineering with Human Pluripotent Stem CellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,673,298April 1, 2021March 31, 2027NAKAYAMA, NAOKIreporter.nih.gov
Dissecting genetic determinants of epigenetic instability in pluripotent stem cellsNIHNational Institute of General Medical Sciences2022 to 2025$1,667,501April 15, 2022February 28, 2026STADTFELD, MATTHIASreporter.nih.gov
The Role of Hippo-Yap1 Signaling in Germ-layer SpecificationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,661,907September 1, 2022June 30, 2027ESTARAS, CONCEPCIONreporter.nih.gov
Gene regulation of retinal cell differentiationNIHNational Eye Institute2021 to 2025$1,653,672May 1, 2013August 31, 2028LIU, WEIreporter.nih.gov
A multi-organoid-on-a-chip platform for interrogating human brain (dys)connectivityNIHNational Institute of Mental Health2024 to 2025$1,652,475April 1, 2024January 31, 2029QUADRATO, GIORGIAreporter.nih.gov
Telomerase RNP Prisonbreaks from Phase-Separated Nuclear BodyNIHNational Institute of General Medical Sciences2023 to 2025$1,649,252July 1, 2023May 31, 2028CHEN, LUreporter.nih.gov
Molecular dissection of Hematopoietic Stem Cell specification triggered by inflammatory mediatorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,627,339February 1, 2022January 31, 2027ESPIN PALAZON, RAQUELreporter.nih.gov
Investigation of Self-Nucleic Acids as a Trigger for NeuroinflammationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,626,825June 1, 2022May 31, 2027CHUNG, HACHUNGreporter.nih.gov
Pro-Type 2 Goblet Cell Antigen Passages in Food Sensitization and ReactivityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,623,949May 4, 2015June 30, 2028HOGAN, SIMON PATRICKreporter.nih.gov
Developmental and genetic function of SHROOM3NIHNational Heart, Lung, and Blood Institute2023 to 2025$1,607,808March 1, 2023February 28, 2027WARE, STEPHANIE Mreporter.nih.gov
DEFINING THE ROLE OF RNA SEQUESTRATION IN MAMMALIAN CELL FATENIHNational Institute of General Medical Sciences2022 to 2025$1,600,000August 18, 2022June 30, 2027DI STEFANO, BRUNOreporter.nih.gov
Learn from the Errors at the Start of Life: Dissect Cellular Fitness Through Dynamics of Chromosomal Instability in EmbryogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$1,588,500September 12, 2025August 31, 2028YANG, MINreporter.nih.gov
Role of OPA1 in Retinal Ganglion Cell Differentiation and the Pathogenesis of Dominant Optic AtrophyNIHNational Eye Institute2022 to 2025$1,576,094September 30, 2022August 31, 2027ZACK, DONALD J.reporter.nih.gov
Dissecting the Molecular Role of TBX1 in the Context of Human Pharyngeal Endoderm DevelopmentNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,574,000May 1, 2022October 31, 2025SEBASTIANO, VITTORIOreporter.nih.gov
Cell-intrinsic and contextual determinants of aging by human glial progenitor cellsNIHNational Institute on Aging2021 to 2025$1,572,186August 15, 2021June 30, 2026GOLDMAN, STEVEN ALANreporter.nih.gov
The Penn LungMAP 3 team: Defining chronic lung diseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,569,484September 1, 2024August 31, 2029MORRISEY, EDWARD Ereporter.nih.gov
Molecular Assessment of Cause and Consequence of Cellular Senescence in Diverse Midbrain Cell Types in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,562,350July 15, 2022June 30, 2027RIESSLAND, MARKUSreporter.nih.gov
Cell Cycle Control of Arterial-Venous SpecificationNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,557,456December 1, 2023November 30, 2027HIRSCHI, KAREN KEMPERreporter.nih.gov
A Fully Patterned Human Neural Tube Model Using MicrofluidicsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,554,627August 15, 2023May 31, 2028FU, JIANPINGreporter.nih.gov
Sonic Hedgehog Signaling in Neocortical Growth and FoldingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,554,342September 30, 2017December 31, 2028HAN, YOUNG-GOOreporter.nih.gov
From variants to mechanisms for cardiac arrhythmiasNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,547,995August 1, 2023June 30, 2028TUCKER, NATHAN Rreporter.nih.gov
An NADH-ChREBP axis in fatty liver disease and dyslipidemiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,532,519February 15, 2023November 30, 2027GOODMAN, RUSSELL PAULreporter.nih.gov
Mechanisms of SOX2 Regulation in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,530,539August 15, 2022July 31, 2027KIM, ALBERT HONG-JAEreporter.nih.gov
Mechanisms of Juxta-Cardiac Field ProgenitorsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,527,860July 1, 2024June 30, 2028CHI, NEIL Creporter.nih.gov
Contribution of AD genetic risk and microglial BIN1 to tauopathyNIHNational Institute on Aging2024 to 2025$1,519,523September 30, 2024June 30, 2029COUFAL, NICOLE GABRIELEreporter.nih.gov
Decoding genome function with DNA methylation and human phenome dataNIHNational Institute of General Medical Sciences2022 to 2025$1,517,009August 1, 2022May 31, 2027HODGES, EMILYreporter.nih.gov
uORF-mediated Translational Control of Cardiac Transcription Factor ExpressionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,512,770April 1, 2023March 31, 2027YAO, PENGreporter.nih.gov
Understanding glial fate restriction in humansNIHNational Institute of Mental Health2024 to 2025$1,509,234July 5, 2024January 31, 2029RAMANATHAN, SHARADreporter.nih.gov
Genome editor therapy for Angelman syndromeNIHNational Institute of Neurological Disorders and Stroke2025$1,508,248August 1, 2025July 31, 2027ZYLKA, MARK J.reporter.nih.gov
Origins of DNA damage driving pathology in human neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,507,453February 10, 2022January 31, 2027PAULL, TANYA Treporter.nih.gov
Human Immune System Humanized Modeling of Down Syndrome Immune Responses to Pluripotent Stem CellsNIHNational Institute of Allergy and Infectious Diseases2025$1,488,578September 16, 2025August 31, 2027BROWN, MATTHEW Ereporter.nih.gov
Cellular Mechanisms of Neuroligin-4 Gene in Human NeuronsNIHNational Institute of Mental Health2022 to 2025$1,478,386January 19, 2022November 30, 2026CHANDA, SOHAMreporter.nih.gov
Anti-inflammatory signals and neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,467,006September 1, 2024June 30, 2028CONTI, BRUNOreporter.nih.gov
Decoding the Interferome by Mapping Genetic Interactions in Human TissueNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,454,584August 10, 2023July 31, 2028GAUDET, RYAN GILBERTreporter.nih.gov
Deciphering the role of FAM210A in cardiac physiopathologyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,447,306August 1, 2023June 30, 2027YAO, PENGreporter.nih.gov
Interrogate FMRP functions in primate brain developmentNIHNational Institute of Mental Health2024 to 2025$1,435,409May 1, 2024February 28, 2029ZHAO, XINYUreporter.nih.gov
Human PSC-based cortical organoid and assembloid systems integrating pericyte and microglial lineages and signalsNIHNational Institute of Mental Health2024 to 2025$1,430,567November 8, 2023October 31, 2028STUDER, LORENZ P.reporter.nih.gov
Systematic identification and characterization of immunogenic double-stranded RNAsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,422,211January 8, 2024November 30, 2028LI, JIN BILLYreporter.nih.gov
Telomere dysfunction and telomerase reactivation in the etiology and progression of liver cancerNIHNational Cancer Institute2022 to 2025$1,415,906December 13, 2021November 30, 2026BATISTA, LUIS FRANCISCO ZIRNBERGERreporter.nih.gov
An Ancient Neural Enhancer that has Rapidly Evolved in the Human LineageNIHNational Institute of Mental Health2024 to 2025$1,411,593August 9, 2024May 31, 2029WILKINSON, MILES FROMEreporter.nih.gov
Dissect the mechanisms underlying interspecies pluripotent stem cell competitionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,406,874February 18, 2022December 31, 2026WU, JUNreporter.nih.gov
Engineer Biomimetic Microfluidic Models to Investigate and Reprogram Tumor Associated Neutrophils for Cancer TherapyNIHNational Cancer Institute2022 to 2025$1,385,581July 15, 2022June 30, 2027BAO, XIAOPINGreporter.nih.gov
Epigenetic and transcriptional mechanisms driving human pigmentation diversityNIHNational Institute of General Medical Sciences2023 to 2025$1,369,708September 1, 2023July 31, 2028BAJPAI, VIVEK KUMARreporter.nih.gov
Elucidating Regulation of Cell Fate Specification in Human Cortical Development to Understand Etiology of Neurodevelopment DisordersNIHNational Institute of Mental Health2024 to 2025$1,369,101August 15, 2024May 31, 2029BHADURI, APARNAreporter.nih.gov
The Role of Aberrant Histone Acetylation in the Pathogenesis of Parkinson’s Disease and Related Synucleinopathies.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,366,666July 17, 2024June 30, 2028SOLDNER, FRANKreporter.nih.gov
Novel strategies for induction of aging in human PSC-derived lineages for modeling Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$1,364,918September 15, 2017March 31, 2030STUDER, LORENZ P.reporter.nih.gov
Epigenetic regulation of transcriptional programmingNIHNational Institute of General Medical Sciences2024 to 2025$1,360,400July 5, 2024May 31, 2029KURODA, MITZI Ireporter.nih.gov
Intersecting clinical, genomic, and experimental investigation to understand the mechanisms and impact of coronary artery patterningNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,357,513August 1, 2024July 31, 2028ASSIMES, THEMISTOCLES Lreporter.nih.gov
Mechanisms of Ischemic Kidney Injury and RepairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,353,395September 1, 1984November 30, 2028BONVENTRE, JOSEPH VINCENTreporter.nih.gov
Modeling and treating T cell immunodeficiency in CHARGE syndrome by ESC- and iPSC-derived thymic epithelial cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,352,273February 1, 2023January 31, 2028LAI, LAIJUNreporter.nih.gov
Investigating Mechanisms of Viral Impairment of Neurogenesis Using Recombinant AAVNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,332,034March 15, 2023February 29, 2028SHTRAHMAN, MATTHEWreporter.nih.gov
Crosstalk Between Nurr1 and Risk Factors of Parkinson's Disease and its Regulation by Nurr1's LigandsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,331,032May 1, 2023April 30, 2027KIM, KWANG-SOOreporter.nih.gov
The Role of GPNMB in Parkinson's Disease.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,312,338August 1, 2024June 30, 2029SOLDNER, FRANKreporter.nih.gov
Morphogenetic signaling from the cell surface to the nucleus during vertebrate eye developmentNIHNational Eye Institute2024 to 2025$1,310,733July 1, 2024June 30, 2028MYERS, BENJAMINreporter.nih.gov
Machine learning methods for interpreting spatial multi-omics dataNIHNational Human Genome Research Institute2023 to 2025$1,302,809February 17, 2023January 31, 2028AZIZI, ELHAMreporter.nih.gov
Understanding Neuronal Cell type-Specific Dysregulation in Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,296,290July 1, 2016June 30, 2029SLAUGENHAUPT, SUSAN Areporter.nih.gov
Optical dissection of human embryonic germ layer patterning mechanisms using microengineered stem cell modelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,254,318June 15, 2022April 30, 2027WILSON, MAXWELL ZANEreporter.nih.gov
Developmental control of chromatin states in cancerNIHNational Cancer Institute2023 to 2025$1,250,703January 1, 2023December 31, 2027DAVIS, IAN Jreporter.nih.gov
REGULATION OF HUMAN HEMATOPOIETIC STEM CELL FATE VIA MLLT3 ISOFORMSNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,243,104March 16, 2019November 30, 2028MIKKOLA, HANNA KATRI ANNIKKIreporter.nih.gov
Interacting Partners of Bestrophin ChannelsNIHNational Institute of General Medical Sciences2023 to 2025$1,233,750April 1, 2023March 31, 2028YANG, TINGTINGreporter.nih.gov
Neuronal Activity-Induced IEG Transcription Factors in Neurodevelopment and PlasticityNIHNational Institute of Neurological Disorders and Stroke2025$1,227,028August 11, 2025May 31, 2033GREENBERG, MICHAEL ELDONreporter.nih.gov
Engineering pluripotent stem cells to evade and promote immunityNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,218,028December 15, 2023November 30, 2027STURGEON, CHRISTOPHER MICHAELreporter.nih.gov
Training in Reproductive SciencesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,210,586July 1, 1979April 30, 2028MELLON, PAMELA Lreporter.nih.gov
Regulation of microtubule organizing centers during mammalian gametogenesisNIHNational Institute of General Medical Sciences2022 to 2025$1,207,922January 1, 2016March 31, 2029JORDAN, PHILIP Wreporter.nih.gov
Understanding thymic epithelial and hematopoietic stem cell-intrinsic immune abnormalities driving T1D in optimized HIS mouse modelsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$1,207,770January 1, 2025December 31, 2026SYKES, MEGANreporter.nih.gov
Molecular mechanisms of intersecting human telomeric functionsNIHNational Institute of General Medical Sciences2023 to 2025$1,205,623February 6, 2023January 31, 2028NANDAKUMAR, JAYAKRISHNANreporter.nih.gov
Spatiotemporal regulation of human islet organogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,203,468April 1, 2024February 28, 2029YOSHIHARA, EIJIreporter.nih.gov
Dissecting the Mechanisms of Quaking-Regulated RNA ProcessingNIHNational Institute of General Medical Sciences2023 to 2025$1,200,000August 1, 2023May 31, 2028FAGG, WILLIAM SAMUELreporter.nih.gov
FMRP regulation of mitochondria and metabolism in mammalian brain developmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,199,340September 1, 2024May 31, 2029ZHAO, XINYUreporter.nih.gov
Characterization of multilineage definitive hematopoietic progenitors from human pluripotent stem cellsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,197,754May 1, 2024March 31, 2026STURGEON, CHRISTOPHER MICHAELreporter.nih.gov
The Role of Modular Super-Enhancers in the Developing Murine and Human RetinaNIHNational Eye Institute2024 to 2025$1,193,028August 1, 2024March 31, 2029DYER, MICHAEL Areporter.nih.gov
Unraveling the tolerogenic potential of lymph node fibroblastic reticular networks in autoimmune diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,191,862July 15, 2024June 30, 2028CREUSOT, REMI Jreporter.nih.gov
The Developmental Transition of Neural Stem Cell Niches in the Human BrainNIHNational Institute of Neurological Disorders and Stroke2025$1,180,687August 1, 2025July 31, 2033ALVAREZ-BUYLLA, ARTUROreporter.nih.gov
High-throughput neurovascular-unit-on-a-chip with OASIS for modeling Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,171,566April 1, 2024March 31, 2029KIM, DEOK-HOreporter.nih.gov
Mechanistic basis for endoplasmic reticulum-driven cytoprotection by selective autophagy in neuronsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,160,388June 1, 2024May 31, 2029ORDUREAU, ALBANreporter.nih.gov
Metabolic control of human endothelial development via the COUP-TF/1-deoxysphingosine axisNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,152,693May 1, 2024March 31, 2028IVANOVA, NATALIA Breporter.nih.gov
Regulation of human telomeraseNIHNational Institute of General Medical Sciences2023 to 2025$1,147,500May 1, 2023March 31, 2028ZHU, JIYUEreporter.nih.gov
Decipher the Function of C2cd4a in MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,146,521January 1, 2023November 30, 2027KUO, TAIYI DIANAreporter.nih.gov
Role of GLIS3 in Human Pancreatic Beta Cell Generation, Survival and ProliferationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,143,917January 1, 2024December 31, 2027CHEN, SHUIBINGreporter.nih.gov
Virus-host interactions regulating innate signaling for human cytomegalovirus latencyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,143,848February 7, 2022June 30, 2025GOODRUM, FELICIA Dreporter.nih.gov
Signaling dynamics in the control of ectoderm patterning and morphogenesisNIHNational Institute of General Medical Sciences2023 to 2025$1,142,985May 1, 2023January 15, 2026WARMFLASH, ARYEHreporter.nih.gov
Cell Control via Spatiotemporal Microenvironmental pH ModulationNIHNational Institute of General Medical Sciences2023 to 2025$1,140,491September 20, 2023August 31, 2028PING, JINGLEIreporter.nih.gov
Engineering microcapsules for scalable differentiation of human pluripotent stem cells into hepatocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,126,776March 1, 2024February 29, 2028REVZIN, ALEXANDERreporter.nih.gov
Functional Interrogation of Type 2 Diabetes-associated Genetic NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,123,786September 19, 2024June 30, 2029CHEN, SHUIBINGreporter.nih.gov
A Conductive Polymer-Stem Cell System to Augment Endogenous Stroke Repair Mechanisms and Improve Functional Stroke RecoveryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,112,422December 1, 2022November 30, 2027GEORGE, PAULreporter.nih.gov
The Role of the O-GlcNAc Modification in X-linked Intellectual DisabilityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,108,431February 1, 2023January 31, 2028WELLS, LANCEreporter.nih.gov
Stem cell-based modeling of type 1 diabetes to accelerate translation of therapiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$1,108,154January 1, 2025December 31, 2026PARENT, AUDREYreporter.nih.gov
Architecture and function of the neural crest genomeNIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,108,070April 1, 2024February 28, 2029SIMOES-COSTA, MARCOSreporter.nih.gov
Control of allelic Gsα expression for regulating hormone signalingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,107,090September 2, 2024July 31, 2028BASTEPE, MURATreporter.nih.gov
Synaptic nanostructure and dysfunction in neurodevelopmental disordersNIHNational Institute of Mental Health2024 to 2025$1,096,124December 1, 2023November 30, 2028ZHOU, QIANGJUNreporter.nih.gov
A Nucleolar Paradigm for Pluripotency of Human Embryonic Stem CellsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,080,544January 12, 2024November 30, 2028WANG, JIANLONGreporter.nih.gov
A non-canonical role for tau in early human brain developmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,051,356May 1, 2024February 28, 2029HEFTI, MARCO MATTHIASreporter.nih.gov
Organoid-guided Precision Hepatology for SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,046,027February 15, 2024December 31, 2028TAKEBE, TAKANORIreporter.nih.gov
Utility of Human Organoids for Safety and Efficiency Evaluations of Genome Editing TherapeuticsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,040,349May 1, 2023April 30, 2027FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Molecular mechanisms of chromatin signaling and epigenetic regulationNIHNational Institute of General Medical Sciences2024 to 2025$1,036,800August 1, 2024May 31, 2029ROTHBART, SCOTTreporter.nih.gov
Training in the Molecular Basis of Autoimmunity and AutoinflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,022,567September 1, 2018August 31, 2028FITZGERALD, KATHERINE A.reporter.nih.gov
Human iPSC intestine mimetics with integrated mesenchymal, endothelial and enteric nervous tissueNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,017,841March 1, 2024January 31, 2028SPENCE, JASONreporter.nih.gov
Developmental Topology of the Human Cerebral CortexNIHNational Institute of Neurological Disorders and Stroke2025$1,008,977December 18, 2024November 30, 2032KRIEGSTEIN, ARNOLDreporter.nih.gov
Histone chaperones and cell state regulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,005,342April 1, 2024March 31, 2029WASYLISHEN, AMANDA RIETTAreporter.nih.gov
Developmental reprogramming and transorganogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$999,632April 1, 2015February 28, 2028ROTHMAN, JOEL H.reporter.nih.gov
Optic Nerve Relays for Vision Restoration and Advancement Optic Nerve Regeneration ResearchNIHNational Eye Institute2024 to 2025$988,461September 1, 2024August 31, 2029WELSBIE, DEREK STUARTreporter.nih.gov
Scalable platforms for understudied histone modifications and modifiersNIHNational Institute of General Medical Sciences2023 to 2025$977,460September 6, 2023June 30, 2027RAO, BALAJI Mreporter.nih.gov
Guided Intracellular Delivery using Precise Area Introduction and Transfection (PAINT)NIHNational Institute of General Medical Sciences2024 to 2025$960,237September 25, 2024July 31, 2028FEDOROV, ANDREI Greporter.nih.gov
How dynamic molecular interactions of RNA Binding Proteins drive post-transcriptional gene expression changesNIHNational Institute of General Medical Sciences2024 to 2025$955,333September 1, 2024August 31, 2029JOVANOVIC, MARKOreporter.nih.gov
A hERG1 potassium channel subdomain is trafficked to the cardiac nucleus: mechanisms and targets of the hERG1NPNIHNational Heart, Lung, and Blood Institute2024 to 2025$954,268July 1, 2024June 30, 2029JONES, DAVID K.reporter.nih.gov
Defining TRPV4-mediated cytoskeletal changes that trigger pathological blood-neural barrier disruptionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$934,185May 1, 2024February 28, 2029MCCRAY, BRETT ANDREWreporter.nih.gov
The Genetic Basis of Human DNA Replication TimingNIHNational Institute of General Medical Sciences2024 to 2025$916,080May 1, 2023February 29, 2028KOREN, AMNONreporter.nih.gov
REGULATION OF PROTEOSTASIS AND TAUOPATHY BY MALTOSE-INDUCED SIGNALINGNIHNational Institute on Aging2024 to 2025$915,125June 1, 2024February 28, 2029DEMONTIS, FABIOreporter.nih.gov
Developmental constraints shaping human sex chromosomes and escape from X inactivationNIHNational Institute of General Medical Sciences2024 to 2025$899,100August 1, 2024July 31, 2029PINTER, STEFAN F.reporter.nih.gov
Resolving epigenetic instability during pluripotent state transitions: a roadmap for exploiting the biomedical potential of dynamic human stem cell statesNIHNational Institute of General Medical Sciences2024 to 2025$898,790June 1, 2024April 30, 2029THEUNISSEN, THOROLDreporter.nih.gov
Unraveling mechanisms of genome regulation to understand and improvehuman healthNIHNational Institute of General Medical Sciences2024 to 2025$890,000September 9, 2016July 31, 2027COTNEY, JUSTIN LEEreporter.nih.gov
Role of SNARE Interactions in Central Synapse FunctionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$883,580December 1, 2003February 28, 2029KAVALALI, EGE Treporter.nih.gov
Modulating the Stem Cell Niche Set Point to Improve Skeletal Muscle RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$843,630August 16, 2024July 31, 2029HICKS, MICHAEL RYANreporter.nih.gov
Decoding the Cell-specific Impact of Epigenomic and Alternative Splicing Regulation during T1D ProgressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$843,179August 1, 2025June 30, 2026CHEN, SHUIBINGreporter.nih.gov
Targeting Myosin to Treat Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$839,264April 12, 2023June 30, 2028FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Host DNA repair pathways in human cytomegalovirus replicationNIHNational Institute of Allergy and Infectious Diseases2025$824,149June 16, 2023May 31, 2028GOODRUM, FELICIA Dreporter.nih.gov
From genetic basis to mechanisms for Heart FailureNIHNational Heart, Lung, and Blood Institute2025$817,208January 3, 2025November 30, 2028XIAO, LINGreporter.nih.gov
Defining developmentally regulated retroelement-based mechanisms to better understand and treat their dysregulation in disease.NIHNational Institute of General Medical Sciences2024 to 2025$812,500August 1, 2024May 31, 2029MODZELEWSKI, ANDREW JOSEPHreporter.nih.gov
Genetics of early onset retinal diseasesNIHNational Eye Institute2023 to 2025$801,046December 1, 2007July 31, 2027CHEN, RUIreporter.nih.gov
Investigating mitochondrial dysfunction in human astrocytes with RTT-causing MECP2 mutationsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$797,500May 5, 2024April 30, 2029BALLAS, NURITreporter.nih.gov
Mechanisms underlying maintenance of cardiac chamber identity in zebrafishNIHNational Heart, Lung, and Blood Institute2025$788,513May 1, 2025April 30, 2029YELON, DEBORAHreporter.nih.gov
Sensory Development in Human Cochlear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2025$781,703December 1, 2024November 30, 2029HASHINO, ERIreporter.nih.gov
Roles of Glial Autophagy in Breast Cancer Brain MetastasisNIHNational Cancer Institute2023 to 2025$780,259April 1, 2023April 2, 2025WANG, CHENRANreporter.nih.gov
Allelic Expression Imbalance in Trisomy 21NIHNational Institute of Neurological Disorders and Stroke2025$780,000June 15, 2025May 31, 2027THAYER, MATHEW Jreporter.nih.gov
Non-synaptic function of Syngap1 in human neurodevelopmental disordersNIHNational Institute of Mental Health2025$772,745March 1, 2025December 31, 2029QUADRATO, GIORGIAreporter.nih.gov
Posttranscriptional modification in lung development and regenerationNIHNational Heart, Lung, and Blood Institute2025$768,985September 1, 2025March 14, 2026QUE, JIANWENreporter.nih.gov
Elucidating the role of CHI3L1/YKL-40 in Alzheimer’s diseaseNIHNational Institute on Aging2024 to 2025$762,862September 1, 2024May 31, 2029HUANG, YU-WEN ALVINreporter.nih.gov
Mechanisms of Cardiac Myosin Heavy Chain Gene RegulationNIHNational Heart, Lung, and Blood Institute2025$761,152August 1, 2025May 31, 2029CHI, NEIL Creporter.nih.gov
Probing Alzheimer synaptopathy using genetically engineered human neurons derived from iPS cellsNIHNational Institute on Aging2025$759,298September 1, 2014April 30, 2030WERNIG, MARIUSreporter.nih.gov
Molecular impediments to fate-specifying pioneer factor activity during developmentNIHNational Institute of General Medical Sciences2023 to 2025$744,845March 3, 2021December 31, 2025MEERS, MICHAEL Preporter.nih.gov
Loss of TDP-43 disrupts the prefrontal neural activity and circuitry: relevance for TDP-43 linked ADRDNIHNational Institute of Neurological Disorders and Stroke2025$736,565September 19, 2022August 31, 2027LI, YUNreporter.nih.gov
Development of a versatile paired prime editing toolkit for CFTR gene correctionNIHNational Heart, Lung, and Blood Institute2025$730,268August 15, 2025May 31, 2030JIANG, TINGTINGreporter.nih.gov
Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's diseaseNIHNational Institute on Aging2023 to 2025$722,395December 1, 2022November 30, 2025PENG, CHUNTEreporter.nih.gov
Generation of Neurons by Force-Mediated Epigenetic Mechanisms through Manipulation of Intrinsic MechanoregulatorsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$721,062April 1, 2023July 1, 2025JUNQUEIRA ALVES, CHRYSTIANreporter.nih.gov
Using 2D and 3D adrenal gland tissues to investigate developmental and disease paradigmsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$718,499May 6, 2025April 30, 2030ZELTNER, NADJAreporter.nih.gov
Overcoming epigenetic barriers to somatic cell reprogramming by the XPC DNA repair complexNIHNational Institute of General Medical Sciences2024 to 2025$716,000August 1, 2024July 31, 2026FONG, YICK WAHreporter.nih.gov
Dissection of noncoding repeats in psychiatric genetics using synthetic regulatory genomics - ResubmissionNIHNational Institute of Mental Health2025$714,615December 1, 2024November 30, 2028MAURANO, MATTHEW THOMASreporter.nih.gov
Developmental Programs as Vulnerabilities in H3.3G34-Mutant High-Grade GliomaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$711,246September 12, 2024August 31, 2029FUNATO, KOSUKEreporter.nih.gov
Promoting metabolic maturity of islet organoids pre- and post-transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$681,562July 21, 2025April 30, 2029SHEA, LONNIE Dreporter.nih.gov
Long-term Phenotypic Alteration in the Lung Epithelium Following Early-life RSV InfectionNIHNational Heart, Lung, and Blood Institute2025$680,562September 15, 2025June 30, 2030FONSECA AGUILAR, WENDYreporter.nih.gov
Platform to accurately recapitulate and perturb cortical development and morphogenesis in vitroNIHNational Institute of Mental Health2025$679,072November 15, 2024October 31, 2029RAMANATHAN, SHARADreporter.nih.gov
Modeling CHARGE Syndrome with Human Inner Ear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2025$670,318December 1, 2024November 30, 2029HASHINO, ERIreporter.nih.gov
Molecular regulation of cell fate and progenitor function in the distal human respiratory airwaysNIHNational Heart, Lung, and Blood Institute2022 to 2025$667,440April 1, 2022March 31, 2027BASIL, MARIA CIOCCAreporter.nih.gov
Understanding renal intrinsic repair by FANCD2NIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$661,694September 3, 2025June 30, 2029MORIZANE, RYUJIreporter.nih.gov
Visualization of extracellular morphogens to understand self-organized patterningNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$659,574August 22, 2024January 15, 2026WARMFLASH, ARYEHreporter.nih.gov
Modeling Human Trophoblast Differentiation and Function Using Pluripotent Stem CellsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$657,377September 1, 2025May 31, 2030THEUNISSEN, THOROLDreporter.nih.gov
Role of Decidual Extracellular Vesicles in Mediating Placental InsufficiencyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$654,671August 1, 2025April 30, 2030TONG, MANCYreporter.nih.gov
Targeting Senescent Macrophages to Improve Heart Failure OutcomesNIHNational Heart, Lung, and Blood Institute2025$651,967August 1, 2025August 2, 2025LI, XIAOreporter.nih.gov
Molecular Aspects of Cytomegalovirus LatencyNIHNational Institute of Allergy and Infectious Diseases2025$639,040December 1, 1984January 31, 2028HANCOCK, MEAGHAN Hreporter.nih.gov
Uncovering Novel Regulatory Pathways and Functions of the Telomerase RNA Component in the Hematopoietic SystemNIHNational Heart, Lung, and Blood Institute2025$623,874December 15, 2024November 30, 2025BATISTA, LUIS FRANCISCO ZIRNBERGERreporter.nih.gov
Influence of developmental programming in adult stem cells and cancerNIHNational Cancer Institute2025$621,570August 8, 2025July 31, 2030MANA, MIYEKOreporter.nih.gov
Combinatorial Perturbation with Multi-Omics Readout to Dissect Etiology of Alzheimer's Disease Using Stem Cell and In Vivo ModelsNIHNational Institute on Aging2025$619,681March 15, 2025January 31, 2030CONG, LEreporter.nih.gov
Enteric Nervous System Development and Function in Human Intestinal OrganoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$615,120July 11, 2022May 31, 2027SPEER, ALLISON LEIGHreporter.nih.gov
Investigating the functional roles of CTSH and PGM1 in beta-cells during autoimmune diabetes developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$614,940February 1, 2022January 31, 2027YE, JODYreporter.nih.gov
Long non-coding RNA MCRL1 regulates human cardiac and hematopoietic differentiation via interacting with β-CateninNIHNational Heart, Lung, and Blood Institute2025$596,401May 1, 2025February 28, 2029YANG, LEIreporter.nih.gov
Determining the Role of Glucose Transporter 1 in Neural Development and DiseaseNIHNational Institute of Neurological Disorders and Stroke2025$595,779April 1, 2025January 31, 2030PEARSON, CAROLINE ALAYNEreporter.nih.gov
Technologies enabling robust closed-loop manufacturing of human pluripotent stem cell-derived cardiomyocytesNIHNational Heart, Lung, and Blood Institute2025$590,283February 1, 2025November 30, 2028PALECEK, SEAN Preporter.nih.gov
Engineering a human neuroimmune specific viral vector from Zika virusNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$589,728July 7, 2023April 30, 2026BARTELLE, BENJAMIN Breporter.nih.gov
Understanding initiation and progression of IPMNs in pancreatic cancerNIHNational Cancer Institute2023 to 2025$583,200September 1, 2023August 31, 2026DESAI, RIDHDHI Rreporter.nih.gov
In vivo 2-photon imaging of retinal biochemistry before and after retinal organoid transplantationNIHNational Eye Institute2023 to 2025$582,786June 1, 2023May 31, 2026BROWNE, ANDREW Wreporter.nih.gov
Function, composition, and mechanism of RNA splicing factories in cardiomyopathyNIHNational Heart, Lung, and Blood Institute2025$580,557December 20, 2022November 30, 2026MURRY, CHARLES Ereporter.nih.gov
The Role of Fos and the BAF Complex in Neuronal Activity-Dependent Chromatin Remodeling and Gene ExpressionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$578,060April 1, 2023March 31, 2028TROWBRIDGE, SARAreporter.nih.gov
Deciphering the Role of Mycobiome (Fungus) in Lung CarcinogenesisNIHNational Cancer Institute2025$569,229December 1, 2024November 30, 2029CHEN, JOYCE HUANHUANreporter.nih.gov
Define the role of chromosome 17q gain in neuroblastoma malignancyNIHNational Cancer Institute2025$562,869January 1, 2025December 31, 2029HUANG, MILLERreporter.nih.gov
Molecular Basis of Human Visual System DisordersNIHNational Eye Institute2025$552,833June 1, 2025May 31, 2029CHEN, RUIreporter.nih.gov
Decoding disease-critical genomic architecture using multimodal single-cell omics dataNIHNational Human Genome Research Institute2025$522,866May 1, 2025April 30, 2030DEY, KUSHAL KUMARreporter.nih.gov
Elucidating how long 3'UTRs form and cause autoinflammationNIHNational Institute of Allergy and Infectious Diseases2025$515,387August 11, 2025July 31, 2030CHUNG, HACHUNGreporter.nih.gov
From genotype to phenotype in a GWAS locus: the role of REST in atherosclerosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$515,160February 1, 2023August 17, 2025ARVANITIS, MARIOSreporter.nih.gov
Mechanisms of Homeodomain Transcription Factor SpecificityNIHNational Institute of General Medical Sciences2025$510,390May 10, 2025March 31, 2030GEBELEIN, BRIANreporter.nih.gov
Epigenetic gene regulation for stem cell fatesNIHNational Institute of General Medical Sciences2025$508,750June 5, 2025March 31, 2030PENG, JAMY C.reporter.nih.gov
Repeat enhancers as drivers of ETV6-RUNX1+ and ETV6-RUNX1-like B-lymphoblastic leukemiaNIHNational Cancer Institute2025$500,719March 1, 2025February 28, 2030RYAN, RUSSELL JAMES HUBBARDreporter.nih.gov
Network Medicine for Alzheimers Disease: Functional Dissection and Pharmacologic Perturbation of a Human Brain Synaptic Regulatory Expression SignatureNIHNational Institute on Aging2025$499,303August 15, 2022July 31, 2027SHULMAN, JOSHUA Mreporter.nih.gov
Mapping and prediction of quantitative transcription factor dosage effects to understand variation in craniofacial morphology and diseaseNIHNational Institute of Dental & Craniofacial Research2024 to 2025$498,000August 5, 2024July 31, 2027NAQVI, SAHINreporter.nih.gov
The role of the transcriptional repressor ZEB2 in human neural crest cell formation and craniofacial pathologyNIHNational Institute of Dental & Craniofacial Research2024 to 2025$497,998September 1, 2024August 31, 2027CHARNEY, REBEKAHreporter.nih.gov
Gene Regulation Underlying Photoreceptor NeurodegenerationNIHNational Eye Institute2025$477,109May 1, 2025April 30, 2030WERT, KATHERINE JEANreporter.nih.gov
Enteroendocrine Regulation of Intestinal MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$475,455September 1, 2021July 31, 2026MCCAULEY, HEATHER Areporter.nih.gov
Mitochondrial mechanisms underlying neural stem and progenitor cell proliferation deficits in 22q11.2 deletion syndromeNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$462,510March 1, 2024February 28, 2029CAMPBELL, PHILIPreporter.nih.gov
Metabolic basis of retinopathy of prematurity and potential treatment with anaplerotic substratesNIHNational Eye Institute2025$462,072April 1, 2025March 31, 2030SINGH, CHARANDEEPreporter.nih.gov
Exploring T. pallidum Pathogenesis in the Placenta Using Novel In Vitro Models of Syphilis During PregnancyNIHNational Institute of Allergy and Infectious Diseases2025$451,956August 15, 2025July 31, 2027MYSOREKAR, INDIRA Ureporter.nih.gov
siRNA-based treatment approach to enhance Gs alpha-mediated hormone signalingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$449,636July 23, 2025June 30, 2027BASTEPE, MURATreporter.nih.gov
Advanced culture and recording system for long-term electrophysiological profiling in human brain organoidsNIHNational Institute of Mental Health2025$449,228March 1, 2025February 28, 2027KIPKE, DARYL Rreporter.nih.gov
Dissecting inter-region communication in human organoid models with dual-color optogenetic probesNIHNational Institute on Aging2024 to 2025$445,884April 1, 2024January 31, 2027XU, GUANGYUreporter.nih.gov
Leverage kidney progenitor plasticity to direct the engineering of next-generation kidney organoidNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$445,870September 2, 2025September 1, 2027LI, ZHONGWEIreporter.nih.gov
Decoding the Ubiquitin and Autophagy Signaling NetworksNIHNational Institute of General Medical Sciences2025$440,000February 3, 2025December 31, 2029ORDUREAU, ALBANreporter.nih.gov
Role of a gut microbiota metabolite indole lactate in myelin repairNIHNational Institute of Neurological Disorders and Stroke2025$439,027July 8, 2025April 30, 2030BHARGAVA, PAVANreporter.nih.gov
Develop a technology for whole-genome sequencing of RNA-DNA triplexesNIHNational Institute of General Medical Sciences2025$435,412September 1, 2025August 31, 2027LIU, YUreporter.nih.gov
Pluripotent stem cell modeling to identify gene/environment influences on placental angiogenesis and severe fetal growth restrictionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$429,000August 6, 2025July 31, 2027SU, EMILY Jreporter.nih.gov
Developing a microfluidic human neurovascular unit system to investigate genetic and age-related risk factors in Alzheimer's diseaseNIHNational Institute on Aging2025$415,390September 30, 2022August 31, 2027SPROUL, ANDREW ALEXANDERreporter.nih.gov
Modeling axon growth and pathfinding of human retinal ganglion cells during development and diseaseNIHNational Eye Institute2025$414,711June 1, 2025May 31, 2029LIU, WEIreporter.nih.gov
Restoring cytoskeletal dynamics to improve circuit integration of transplanted photoreceptorsNIHNational Eye Institute2024 to 2025$414,305January 1, 2024December 31, 2025GOMEZ, TIMOTHY Mreporter.nih.gov
Elucidating the structure function relationship between TPP1 and telomere length control through deep scanning mutagenesisNIHNational Institute on Aging2025$413,385September 1, 2025August 31, 2027HOCKEMEYER, DIRKreporter.nih.gov
Development of ganglioside specific IgGs for the treatment of Guillian-Barré SyndromeNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$411,241February 19, 2024December 31, 2026SZYMANSKI, CHRISTINE M.reporter.nih.gov
How cell maturation is regulated by circadian and metabolic rhythmsNIHNational Institute of General Medical Sciences2025$406,250June 12, 2025April 30, 2030ALVAREZ, JUAN Rreporter.nih.gov
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsNIHNational Institute of Allergy and Infectious Diseases2025$402,424September 1, 2025August 31, 2029GOODRUM, FELICIA Dreporter.nih.gov
Neural exosome therapeutics for treating opioid-induced brain hypoxia injuriesNIHNational Institute on Drug Abuse2025$399,997August 15, 2025July 31, 2026BAKER, EMILY Wreporter.nih.gov
The Regulatory R-loops in Pluripotency, Early Development, and Tissue HomeostasisNIHNational Institute of General Medical Sciences2025$393,750July 5, 2024April 30, 2029HUANG, XINreporter.nih.gov
Enhancing the TCR-induced Response of HLA-E-restricted Regulatory CD8 T Cells to Promote Allograft ToleranceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$390,019June 14, 2024July 1, 2025CHOI, JOHN YONGJOONreporter.nih.gov
Virus-host interactions regulating innate signaling for human cytomegalovirus latencyNIHNational Institute of Allergy and Infectious Diseases2025$388,311July 1, 2025January 31, 2027GOODRUM, FELICIA Dreporter.nih.gov
Roles of microRNAs in animal developmentNIHNational Institute of General Medical Sciences2025$387,500May 1, 2025February 28, 2030COCHELLA, LUISAreporter.nih.gov
Epigenetic Regulation in Human Embryonic Stem Cell Lineage SpecificationNIHNational Institute of General Medical Sciences2025$380,540September 1, 2025June 30, 2030SPARKS, NICOLE RENEEreporter.nih.gov
Development of an immune evasive stem cell line for Type 1 diabetes regenerative therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$372,067September 7, 2025August 31, 2026SHEN, CHRISTOPHERreporter.nih.gov
Characterizing the effects of extracellular matrix viscoelasticity on dendritic cell activationNIHNational Cancer Institute2022 to 2025$362,985April 1, 2022March 31, 2026JUNG, WEI-HUNGreporter.nih.gov
Transcriptional and Epigenetic Control of Totipotency and Early Development by Zfp281NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$339,808August 6, 2018April 30, 2030WANG, JIANLONGreporter.nih.gov
Investigating the role of cGAS signaling and microglial senscence in tauopathyNIHNational Institute on Aging2023 to 2025$326,462August 5, 2023July 31, 2025AMIN, SADAFreporter.nih.gov
Development of immune evasive strategies for allogeneic cell replacement therapiesNIHNational Institute of Allergy and Infectious Diseases2025$307,091May 21, 2025April 30, 2026SHEN, CHRISTOPHERreporter.nih.gov
Development of a gene edited platform to enable human allogeneic cell replacement therapyNIHNational Institute of Allergy and Infectious Diseases2025$305,855August 18, 2025July 31, 2026SHEN, CHRISTOPHERreporter.nih.gov
Learning gene regulatory networks under latent confounding and data dependenceNIHNational Institute of General Medical Sciences2025$267,098August 1, 2025April 30, 2029ZHOU, QINGreporter.nih.gov
Deciphering the underlying mechanisms of craniofacial spliceosomopathiesNIHNational Institute of Dental & Craniofacial Research2024 to 2025$251,033September 25, 2024August 31, 2026GRIFFIN, CASEYreporter.nih.gov
A Phenotypical Brain Organoids for Neurodevelopmental DisordersNIHNational Institute of Neurological Disorders and Stroke2025$249,001August 5, 2022May 31, 2028WANG, LUreporter.nih.gov
Investigating the role of cGAS signaling and microglial senscence in tauopathyNIHNational Institute on Aging2025$244,020August 5, 2023July 31, 2028AMIN, SADAFreporter.nih.gov
Using the continuum of genetic causality to investigate trans regulatory mechanisms.NIHNational Human Genome Research Institute2024 to 2025$239,222August 29, 2024August 31, 2026TOVAR, ADELAIDE Ereporter.nih.gov
Thioredoxin derivatives for radiation mitigationNIHNational Institute of Allergy and Infectious Diseases2025$234,255August 11, 2025February 28, 2026KANG, YUBINreporter.nih.gov
Unraveling Metastasis Drivers in Small Cell Lung Cancer via Human Pluripotent Stem Cell-Based ApproachNIHNational Cancer Institute2025$230,010March 1, 2025February 28, 2027CHEN, JOYCE HUANHUANreporter.nih.gov
Characterizing and treating peripheral nervous system dysfunction in Sanfilippo SyndromeNIHNational Institute of Neurological Disorders and Stroke2025$226,500February 1, 2025January 31, 2027WEISS, RYAN JOSEPHreporter.nih.gov
Identifying human-specific neural progenitors and their role in neurodevelopmentNIHNational Institute of Mental Health2025$224,101May 1, 2023August 31, 2028JANG, SUMINreporter.nih.gov
The role of cis-regulatory elements in the inheritance of transcriptional memory through mitosis.NIHNational Institute of General Medical Sciences2023 to 2025$218,032August 1, 2023July 31, 2026OPRESCU, STEPHANIE NICOLEreporter.nih.gov
A signaling crosstalk regulation in neural crest-derived cranial sutureNIHNational Institute of Dental & Craniofacial Research2024 to 2025$214,938April 8, 2024March 31, 2027ZHAO, XIAOLEIreporter.nih.gov
Comparative analysis of photoreceptor developmental mechanisms in retinal organoidsNIHNational Eye Institute2024 to 2025$207,060March 1, 2024February 28, 2026HAGEN, JOANNA FRANCES DONNELLYreporter.nih.gov
Probing mechanisms of long QT type 2-associated neuronal dysfunction using gene-edited stem cell-derived neuronsNIHNational Institute of Neurological Disorders and Stroke2025$195,000December 1, 2024November 30, 2026JONES, DAVID K.reporter.nih.gov
Fibrotic remodeling of lymph nodes disrupts T cell function in fibrosis and cancerNIHNational Cancer Institute2024 to 2025$182,098January 1, 2024May 18, 2025BINGHAM, GRACE Creporter.nih.gov
miRNA Control of Synaptic Stability and Structural PlasticityNIHNational Institute on Aging2024 to 2025$170,036September 1, 2019March 31, 2028WOODS, BRANDONreporter.nih.gov
Molecular impact of endolysosomal dysfunction on neuron-glia communication pathwaysNIHNational Institute on Aging2022 to 2025$163,747January 29, 2023April 28, 2025MORSHED, NADER FRANCISreporter.nih.gov
The Role of Tunneling Nanotubes and Mitochondrial programming in HIV-Associated Placental DysfunctionNIHNational Institute of Allergy and Infectious Diseases2025$156,744September 1, 2025August 31, 2027TOMOYA MICHITA, RAFAELreporter.nih.gov
Stem cell-based 3D model of human yolk sac for experimental interrogationsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$156,500April 15, 2025March 31, 2027MARIKAWA, YUSUKEreporter.nih.gov
New approach methodologies to assess reproductive risks of memory-enhancing dietary supplementsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$156,500September 26, 2025August 31, 2027MARIKAWA, YUSUKEreporter.nih.gov
Shining light on the mechanisms of primate gastrulation: development of high-throughput, optogenetic tools for understanding embryonic developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$152,324July 22, 2024July 21, 2027RUFO, JOSEPHreporter.nih.gov
Role of BMP signaling in cardiac neural crest developmentNIHNational Heart, Lung, and Blood Institute2025$150,876August 1, 2025June 30, 2027GANDHI, SHASHANKreporter.nih.gov
Cell-type specific and activity-dependent characterization of non-coding autism de novo variants in human stem cell-derived neuronsNIHNational Institute of Mental Health2023 to 2025$146,206April 24, 2023April 23, 2026WILLIAMS, SARAH ELIZABETHreporter.nih.gov
Utilizing Causal X-Linked Intellectual Disability Variants to Gain Insight into the O-GlcNAc Transferase EnzymeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$145,264January 1, 2023December 31, 2025MAYFIELD, JOHNATHAN MARTINreporter.nih.gov
Cytoskeletal regulation of gut tube organogenesis and subsequent maturation of stem cell-derived isletsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$138,753September 15, 2025July 31, 2028HOGREBE, NATHANIEL JAMESreporter.nih.gov
Regulating host neural activity to improve retinal ganglion cell replacement therapiesNIHNational Eye Institute2025$132,597February 1, 2025January 31, 2026SOUCY, JONATHAN Rreporter.nih.gov
Unlocking the Potential of the GSC-Associated lncRNA GIHCG as a Therapeutic Target in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2025$131,360September 1, 2025August 31, 2029HAZRA, RASMANIreporter.nih.gov
Elucidating the role of selective Golgi remodeling in cellular homeostasisNIHNational Institute of General Medical Sciences2025$125,000July 17, 2025June 30, 2027HICKEY, KELSEYreporter.nih.gov
Deciphering terminal selector functions in motor neurons: from worms to humansNIHNational Institute of Neurological Disorders and Stroke2025$121,230August 1, 2025July 31, 2026SMITH, JAYSON JAVELLreporter.nih.gov
H2AJ as a regulator of placental senescence and genome organizationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$121,042April 16, 2023April 15, 2027JENSEN, TYLER BARRYreporter.nih.gov
Defining the role of ILF2-ILF3 in human cell fateNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$102,201August 5, 2024August 4, 2027PARK, EMILY Jreporter.nih.gov
Characterization of the Integrator-Z3 module as a regulator of neuronal differentiationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$98,512July 1, 2024June 30, 2027HASELEY, MARYCLAIREreporter.nih.gov
Determining how a single-residue PKR mutation found in patients with familial dystonia causes aberrant PKR activationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$98,512July 1, 2024June 30, 2028GERTIE, JAKE ANDERSreporter.nih.gov
Self-assembling cardiac organoids to model myovascular interactions in human cardiac tissue regenerationNIHNational Heart, Lung, and Blood Institute2024 to 2025$97,035September 30, 2024September 29, 2027PARKER, LAUREN ELIZABETHreporter.nih.gov
Elucidating the role of FBLL1 in ribosome function during neuronal differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$92,149September 1, 2024August 31, 2026ALSHAWI, SARAH ANNreporter.nih.gov
ASXL3 Links Chromatin Biology to Neurodevelopment DisordersNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$85,675September 1, 2024August 31, 2027PEIRENT, EMILY ROSEreporter.nih.gov
Multispecies investigation of early pregnancy loss mechanisms using bioengineered stem cell modelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$83,460January 1, 2024December 31, 2025ABEL, ASHLEYreporter.nih.gov
Functional Genomic Interrogation of Autism Spectrum Disorder Genetic Risk on Microglia-Neuronal InteractionsNIHNational Institute of Mental Health2024 to 2025$83,180July 1, 2024June 30, 2028HAWKEN, NATALIEreporter.nih.gov
Enhancing robustness of human pluripotent stem cell differentiation to cardiomyocytes by uncovering on- and off-target differentiation trajectories via single nucleus multi-omicsNIHNational Heart, Lung, and Blood Institute2024 to 2025$79,670September 30, 2024June 29, 2027FEENEY, AUSTIN K.reporter.nih.gov
Tissue elasticity and viscosity modulates macrophage-fibroblast signaling in cardiac fibrosisNIHNational Heart, Lung, and Blood Institute2025$78,040April 1, 2025March 31, 2026ATCHA, HAMZAreporter.nih.gov
Identification and structural basis of a potential licensing factor of the Integrator cleavage moduleNIHNational Cancer Institute2024 to 2025$76,945February 1, 2024May 31, 2025WASHBURN, MADELINE Kreporter.nih.gov
3D Printing Hydrogel Vasculature and Bioactive Cues within Brain OrganoidsNIHNational Institute of Neurological Disorders and Stroke2025$75,052December 1, 2025October 31, 2028FARSHEED, ADAMreporter.nih.gov
Defining the roles of host factors and innate immune signaling in the ocular tropism of enterovirus D70NIHNational Institute of Allergy and Infectious Diseases2025$75,052September 1, 2025August 31, 2027CREISHER, PATRICKreporter.nih.gov
Investigating the role of Yap/Taz in neural crest-derived cardiac developmentNIHNational Heart, Lung, and Blood Institute2024 to 2025$74,812September 1, 2024August 31, 2027ERHARDT, SHANNON NICOLEreporter.nih.gov
Novel inner ear organoid models for studying hair cells in normal development and in the deaf-blindness disease Usher Syndrome Type 1FNIHNational Institute on Deafness and Other Communication Disorders2024 to 2025$74,402September 1, 2024August 31, 2026NIST-LUND, CARLreporter.nih.gov
Unraveling alphavirus neuroinvasion: Molecular insights from a stem cell based blood-brain barrier modelNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$68,339September 1, 2024December 31, 2025ALVAREZ, PABLOreporter.nih.gov
Investigating the chromatin landscape of ALT telomeresNIHNational Cancer Institute2025$54,538March 1, 2025February 28, 2029REX, MADISONreporter.nih.gov
Regulation of mesoderm fate patterning through multiscale dynamicsNIHNational Institute of General Medical Sciences2025$49,538January 1, 2025December 31, 2027JOHNSON, AMANDA BROOKEreporter.nih.gov
Evaluation of Human Retinal Ganglion Cell Regenerative PotentialNIHNational Eye Institute2025$49,538December 1, 2024May 31, 2025CEISEL, ANNELIESEreporter.nih.gov
Characterizing EZH1 Gain of function mutations to understand neurodevelopmental disease and inform EZH1-inhibitor innovationNIHNational Institute of Neurological Disorders and Stroke2025$49,538August 6, 2025August 5, 2028BAUER, JAMESreporter.nih.gov
Unveil the functional role of RNA spatial localization in neuronal function and neurodegeneration by developing novel CRISPR-TO toolsNIHNational Institute of Neurological Disorders and Stroke2025$49,538September 30, 2025August 29, 2028FU, MAYLINreporter.nih.gov
Human-specific splicing regulation in neurogenesis and diseaseNIHNational Institute of Neurological Disorders and Stroke2025$48,233January 1, 2025July 31, 2025MOSS, NICOLE Dreporter.nih.gov
Investigating the role of YAP1 in blood cell specificationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$46,777September 1, 2024September 30, 2025ABRAHAM, ELIZABETHreporter.nih.gov
Modeling Chromosomal Mosaicism During Early Human Embryogenesis on Microraft Array PlatformNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$45,021December 13, 2024July 12, 2026JAN, IANreporter.nih.gov
Investigating COUP-TFII in human vein developmentNIHNational Heart, Lung, and Blood Institute2025$43,071January 13, 2025January 12, 2028PYKE, ALANNAreporter.nih.gov
Mechanisms underlying the development, evolution, and function of human-specific cortical dopaminergic interneuronsNIHNational Institute of Mental Health2025$38,524April 1, 2025March 31, 2029RISGAARD, RYAN DAVIDreporter.nih.gov
Investigating the function of the autism spectrum disorder risk genes RFX3 and RFX4 during human cortical developmentNIHNational Institute of Mental Health2025$36,673September 1, 2025August 31, 2029DETERMAN, JULIANNAreporter.nih.gov
PQBP1 as a central regulator of inflammation in neurodegenerative diseasesNIHNational Institute of Neurological Disorders and Stroke2025$36,538February 1, 2025January 31, 2029ALLEN, DALE Sreporter.nih.gov
Human Pluripotent Stem Cells and Organoids for Salivary Gland RegenerationNIHNational Institute of Dental & Craniofacial Research2025$35,204July 1, 2025June 30, 2028SHERWOOD, LAURAreporter.nih.gov
The development and connectivity of starburst amacrine cells in human retinal organoidsNIHNational Eye Institute2025$29,974January 1, 2025May 31, 2025TAYLOR, ALLISONreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of WashingtonSeattle, WA7$82.4 million0$0
University of California, San DiegoLa Jolla, CA18$50.3 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY13$36.3 million0$0
National Collegiate Inventors and Innovators AllianceHadley, MA1$27.5 million0$0
Stanford UniversityStanford, CA15$27.2 million0$0
University of Wisconsin-MadisonMadison, WI9$24.4 million0$0
University of UtahSalt Lake City, UT2$22.2 million0$0
University of Michigan at Ann ArborAnn Arbor, MI15$21.6 million0$0
University of California, San FranciscoSan Francisco, CA9$20.1 million0$0
University of California-IrvineIrvine, CA10$20.1 million0$0
Washington UniversitySaint Louis, MO13$18.3 million0$0
Weill Medical Coll of Cornell UnivNew York, NY11$18.1 million0$0
University of RochesterRochester, NY8$15.5 million0$0
Massachusetts General HospitalBoston, MA8$15.2 million0$0
Rockefeller UniversityNew York, NY6$15.2 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY9$14.7 million0$0
University of PennsylvaniaPhiladelphia, PA10$14.3 million0$0
Ut Southwestern Medical CenterDallas, TX5$14.2 million0$0
Columbia University Health SciencesNew York, NY13$14.1 million0$0
Columbia UniversityNew York, NY4$14 million0$0
University of California-BerkeleyBerkeley, CA6$13.2 million0$0
Indiana University IndianapolisIndianapolis, IN8$13.1 million0$0
University of California-Santa CruzSanta Cruz, CA1$12 million0$0
Johns Hopkins UniversityBaltimore, MD11$11.5 million0$0
Duke UniversityDurham, NC8$10.7 million0$0
Brigham and Women's HospitalBoston, MA6$9.8 million0$0
Case Western Reserve UniversityCleveland, OH4$9.8 million0$0
University of California Los AngelesLos Angeles, CA8$9.5 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA4$9.2 million0$0
University of Connecticut SCH of Med/dntFarmington, CT6$8.8 million0$0
University of FloridaGainesville, FL2$8.3 million0$0
Vanderbilt UniversityNashville, TN5$8.2 million0$0
University of Southern CaliforniaLos Angeles, CA7$8.1 million0$0
Boston Children's HospitalBoston, MA6$7.7 million0$0
Rogosin InstituteNew York, NY1$7.4 million0$0
Harvard UniversityCambridge, MA6$7.3 million0$0
Baylor College of MedicineHouston, TX7$7.3 million0$0
Seattle Children's HospitalSeattle, WA2$7.2 million0$0
University of Colorado DenverAurora, CO4$7.1 million0$0
University of Georgia Research Foundation IncAthens, GA8$6.9 million0$0
Broad Institute, Inc.Cambridge, MA4$6.4 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH4$6.3 million0$0
Harvard Medical SchoolBoston, MA6$6.1 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA2$5.4 million0$0
Albert Einstein College of MedicineBronx, NY5$5.4 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA2$4.9 million0$0
Boston University Medical CampusBoston, MA2$4.9 million0$0
Michigan State UniversityEast Lansing, MI2$4.7 million0$0
Emory UniversityAtlanta, GA2$4.5 million0$0
Arizona State UniversityScottsdale, AZ3$4.2 million0$0
ST. Jude Children's Research HospitalMemphis, TN4$4.2 million0$0
Massachusetts Institute of TechnologyCambridge, MA1$4.1 million0$0
University of Colorado at BoulderBoulder, CO2$3.9 million0$0
University of Nebraska Medical CenterOmaha, NE1$3.8 million0$0
Colorado State UniversityFort Collins, CO2$3.7 million0$0
Purdue UniversityWest Lafayette, IN2$3.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX4$3.5 million0$0
Mclean HospitalBelmont, MA2$3.4 million0$0
Brown UniversityProvidence, RI2$3.4 million0$0
Yale UniversityNew Haven, CT4$3.4 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC3$3.2 million0$0
Vanderbilt University Medical CenterNashville, TN1$3.2 million0$0
University of California at DavisDavis, CA2$3.2 million0$0
University of Texas Med BR GalvestonGalveston, TX2$3.2 million0$0
University of ArizonaTucson, AZ2$3.1 million0$0
Epicypher, Inc.Research Triangle Park, NC1$3 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD2$3 million0$0
New York University School of MedicineNew York, NY2$2.9 million0$0
Meso Scale Diagnostics, LLCRockville, MD1$2.8 million0$0
University of Missouri-ColumbiaColumbia, MO1$2.6 million0$0
University of California-RiversideRiverside, CA1$2.4 million0$0
Northwestern University at ChicagoChicago, IL1$2.4 million0$0
Beth Israel Deaconess Medical CenterBoston, MA1$2.4 million0$0
University of California-Santa BarbaraSanta Barbara, CA3$2.4 million0$0
SUNY at Stony BrookStony Brook, NY2$2.4 million0$0
University of Texas HLTH Science CenterSan Antonio, TX1$2.2 million0$0
Cornell UniversityIthaca, NY1$2.2 million0$0
Medical College of WisconsinMilwaukee, WI1$2.1 million0$0
Syracuse UniversitySyracuse, NY1$2 million0$0
Magee-Women's Res Inst and FoundationPittsburgh, PA1$2 million0$0
Dana-Farber Cancer InstBoston, MA1$2 million0$0
Northeastern UniversityBoston, MA1$2 million0$0
Utah State UniversityLogan, UT1$1.9 million0$0
University of Maryland BaltimoreBaltimore, MD1$1.9 million0$0
Ohio State UniversityColumbus, OH1$1.9 million0$0
Rumi Scientific, Inc.New York, NY1$1.9 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL1$1.9 million0$0
William Marsh Rice UniversityHouston, TX2$1.8 million0$0
University of CincinnatiCincinnati, OH2$1.8 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA1$1.7 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA2$1.7 million0$0
Steadman Philippon Research InstituteVail, CO1$1.7 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA1$1.6 million0$0
Iowa State UniversityAmes, IA1$1.6 million0$0
Dartmouth CollegeHanover, NH3$1.6 million0$0
University of Massachusetts AmherstAmherst, MA2$1.6 million0$0
University of VirginiaCharlottesville, VA1$1.6 million0$0
Upstate Medical UniversitySyracuse, NY1$1.5 million0$0
University of Texas at AustinAustin, TX1$1.5 million0$0
San Diego Biomedical Research InstituteSan Diego, CA1$1.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025448$285,523,2160$0
2024327$220,982,9410$0
2023227$163,647,7390$0
2022169$124,017,7840$0
2021100$75,388,2410$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 8 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)PA-25-302NIHJanuary 7, 2028$50,000Notice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 75 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 75 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 75 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 75 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 75 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 75 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 75 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 75 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 75 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 75 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 75 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 75 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 75 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 75 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 75 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 75 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.