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Data / Research funding / Digestive Diseases

Digestive Diseases: 9,233 NIH awards ($11.2B) to 910 organizations

9,233 NIH awards ($11.2B) in the NIH spending category Digestive Diseases, to 910 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 9,233 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$472,070,715December 1, 2024November 30, 2025CURRIER, JUDITH S.reporter.nih.gov
AIDS Clinical Trial Group Laboratory CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$56,714,107January 1, 2014November 30, 2027ALDROVANDI, GRACE Mreporter.nih.gov
Implementing Vaccine and Treatment Evaluation Unit (VTEU) Clinical SiteNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$44,959,734August 13, 2025November 30, 2026KOTLOFF, KAREN L.reporter.nih.gov
Epidemiology of Diabetes Interventions and Complications (EDIC) StudyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$35,015,476September 22, 2011June 30, 2027GUBITOSI-KLUG, ROSE Areporter.nih.gov
Mayo Clinic Comprehensive Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$29,249,641April 25, 1997August 31, 2030WILLMAN, CHERYL LYNNreporter.nih.gov
New Horizons in the Prevention and Treatment of Food AllergyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$25,961,502April 4, 2024February 28, 2031WOOD, ROBERT Areporter.nih.gov
University of North Carolina Global HIV Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,477,809February 1, 2007November 30, 2027ERON, JOSEPH Jreporter.nih.gov
Environmental triggers of early-onset colorectal cancer: interactions between microplastics and pks+ E coli in early-life gut colonizationNIHNational Cancer Institute2021 to 2025$22,669,275August 1, 1997July 31, 2026TUVESON, DAVID Areporter.nih.gov
Moffitt Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$22,007,955February 18, 1998January 31, 2027CLEVELAND, JOHN L.reporter.nih.gov
UT Southwestern Medical Center Simmons Comprehensive Cancer CenterNIHNational Cancer Institute2021 to 2025$21,900,548September 1, 2010July 31, 2026ARTEAGA, CARLOS Lreporter.nih.gov
UCLA AIDS Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,546,764February 1, 2007November 30, 2027LANDOVITZ, RAPHAEL Jreporter.nih.gov
Boston HIV CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,445,869January 15, 2007November 30, 2027KURITZKES, DANIEL R.reporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
University of Arizona Cancer Center - Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$21,155,920July 1, 1997July 31, 2027THEODORESCU, DANreporter.nih.gov
Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$19,528,719June 1, 1997June 30, 2028STEIDL, ULRICHreporter.nih.gov
Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer RiskNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$18,807,472August 1, 2018August 31, 2030DURAND, CHRISTINE MARIEreporter.nih.gov
NIAID VIROLOGY QUALITY ASSURANCE (VQA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,732,468June 21, 2025June 20, 2026DENNY, THOMASreporter.nih.gov
Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseasesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$17,556,074August 1, 2023July 31, 2028PERANTEAU, WILLIAM H.reporter.nih.gov
Data Coordinating Center for the Type 1 Diabetes in Acute Pancreatitis ConsortiumNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$17,043,926September 17, 2020July 31, 2025CHINCHILLI, VERNON Mreporter.nih.gov
International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,840,939May 1, 2025April 30, 2027ROHNER, ELIANEreporter.nih.gov
Biology of the Hormonal Regulation of Cancer and Immuno Oncology Outcomes Research Proposal.NIHNational Cancer Institute2021 to 2025$15,746,743August 1, 1997June 30, 2027COUSSENS, LISA Mreporter.nih.gov
Pancreatitis-induced initiation of early onset pancreatic cancerNIHNational Cancer Institute2021 to 2025$15,447,190February 1, 2025January 31, 2026SHAW, REUBENreporter.nih.gov
Center for Cellular Metabolism Research in OklahomaNIHNational Institute of General Medical Sciences2021 to 2025$15,159,612February 5, 2021January 31, 2027XIA, LIJUNreporter.nih.gov
Pediatric Acute Liver Failure Immune Response Network (PALF IRN): Treatment for Immune Mediated Pathophysiology (TRIUMPH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$13,418,019June 15, 2021May 31, 2027ALONSO, ESTELLA M.reporter.nih.gov
Pitt-Ohio State Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,065,770February 1, 2007November 30, 2027RIDDLER, SHARONreporter.nih.gov
Hepatobiology and Toxicology COBRENIHNational Institute of General Medical Sciences2021 to 2025$12,863,981June 10, 2016March 31, 2027MCCLAIN, CRAIG J.reporter.nih.gov
Vanderbilt HIV Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,733,650February 1, 2007November 30, 2027HAAS, DAVID Wreporter.nih.gov
Functional Microbiomics, Inflammation and PathogenicityNIHNational Institute of General Medical Sciences2021 to 2025$12,492,994March 1, 2018February 29, 2028LAMONT, RICHARD Jreporter.nih.gov
CURE CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,461,433January 1, 2007November 30, 2027SPECTOR, STEPHEN Areporter.nih.gov
AIDS Linked to the IntraVenous Experience (ALIVE) StudyNIHNational Institute on Drug Abuse2021 to 2025$12,226,379January 1, 2014May 31, 2030MEHTA, SHRUTI Hreporter.nih.gov
COBRE in Digestive and Liver DiseaseNIHNational Institute of General Medical Sciences2021 to 2025$11,909,573April 3, 2020June 30, 2030DUNCAN, STEPHEN Areporter.nih.gov
Durable Alteration of the Human Immune system after Infection or ImmunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,785,761June 8, 2009May 31, 2029CHUNG, RAYMOND Treporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Indiana University Data Coordinating CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$11,773,646August 1, 2018June 30, 2029TU, WANZHUreporter.nih.gov
Center for Pre-Clinical Cancer ResearchNIHNational Institute of General Medical Sciences2021 to 2025$11,277,290March 1, 2021February 28, 2027FRANCIS, JOSEPHreporter.nih.gov
A Follow-up Study for Causes of Cancer in Black WomenNIHNational Cancer Institute2021 to 2025$11,271,706September 21, 2012August 31, 2027PALMER, JULIE Rreporter.nih.gov
Mays Cancer Center at UT Health SANIHNational Cancer Institute2021 to 2025$11,193,809August 1, 1997July 31, 2026ZHENG, LEIreporter.nih.gov
Administrative Supplement for the NCI P30 CCSG to extend partnerships with comprehensive cancer control coalitions to study implementation of evidence-based cancer control interventionsNIHNational Cancer Institute2021$11,079,774January 1, 1997March 31, 2022LYNCH, THOMAS JAMESreporter.nih.gov
Utility of Biomarkers of Rejection and Kidney Injury in Tailoring Liver Transplant ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,920,671September 6, 2021June 30, 2028BOIKE, JUSTINreporter.nih.gov
Reagent Program for HIV and other Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,735,388October 15, 2023January 13, 2024RASHID, SUJATHAreporter.nih.gov
Liver Cirrhosis Network: Scientific and Data Coordination CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$10,655,826August 28, 2021July 31, 2027SMITH, ABIGAILreporter.nih.gov
Addressing risk through Community Treatment for Infectious disease and Opioid use disorder Now (ACTION) among justice-involved populationsNIHNational Institute on Drug Abuse2021 to 2025$10,550,278September 30, 2020July 31, 2026SPRINGER, SANDRA ANNreporter.nih.gov
Kansas Center for Metabolism and Obesity REsearch (KC-MORE)NIHNational Institute of General Medical Sciences2022 to 2025$10,233,525April 1, 2022February 28, 2027WEINMAN, STEVEN Areporter.nih.gov
Colorado Head and Neck Cancer SPORENIHNational Cancer Institute2021 to 2025$10,073,085September 1, 2021August 31, 2026JIMENO, ANTONIOreporter.nih.gov
Thailand HIV/AIDS and Infectious Disease Clinical Trials Unit (THAI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,070,868March 15, 2007November 30, 2027SUPPARATPINYO, KHUANCHAIreporter.nih.gov
Southern Liver Health CohortNIHNational Cancer Institute2023 to 2025$10,038,112September 21, 2021August 31, 2027HOYO, CATHRINEreporter.nih.gov
The Johns Hopkins University - Uganda Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,910,249February 5, 2007November 30, 2027FOWLER, MARY GLENNreporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,640,870August 26, 2021September 30, 2024LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
Chronic Pancreatitis Clinical Research Consortium (CPCRC) Data Coordinating Center (CPCRC-DCC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,632,234September 28, 2015June 30, 2030LI, LIANGreporter.nih.gov
Determining the mechanism of pks+ E.coli-associated carcinogenesis in early onset colorectal cancer.NIHNational Cancer Institute2022 to 2025$9,558,240September 20, 2022August 31, 2027O'REILLY, EILEEN MARYreporter.nih.gov
Tissue destruction and healing in Celiac DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$9,512,977September 15, 2022July 31, 2027JABRI, BANAreporter.nih.gov
Targeting the A2B Adenosine Receptor for Immunoprevention of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$9,423,468September 15, 2023March 14, 2027WU, XIANGWEIreporter.nih.gov
Yale Head and Neck Cancer SPORE: Overcoming Treatment Resistance in Head and Neck CancerNIHNational Institute of Dental & Craniofacial Research2021 to 2024$9,412,704September 22, 2020June 30, 2026BURTNESS, BARBARAreporter.nih.gov
Childhood Liver Disease Research Network (ChiLDReN) Scientific and Data Coordinating CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,404,513September 18, 2002May 31, 2029MAGEE, JOHN Creporter.nih.gov
Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyNIHNational Cancer Institute2021 to 2025$9,251,154September 19, 2016August 31, 2026ULRICH, CORNELIA Mreporter.nih.gov
COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepositoryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,161,352September 15, 2019August 31, 2029MARTIN, MARTIN Greporter.nih.gov
COBRE: Eukaryotic Pathogens Innovation Center (EPIC)NIHNational Institute of General Medical Sciences2022 to 2025$9,118,734July 15, 2022May 31, 2027MORRIS, JAMES CULVINreporter.nih.gov
Colon Cancer Family Registry CohortNIHNational Cancer Institute2021 to 2025$8,978,119May 1, 2013April 30, 2028JENKINS, MARK Areporter.nih.gov
Statistical Methods for Integrative Genomics in CancerNIHNational Cancer Institute2021 to 2025$8,721,062July 1, 2016August 31, 2027GAUDERMAN, WILLIAM JAMESreporter.nih.gov
Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Supporting Financial Sustainability, Advanced Methods, and Knowledge TranslationNIHNational Institute on Drug Abuse2021 to 2025$8,690,640July 15, 2015April 30, 2030SCHACKMAN, BRUCE Rreporter.nih.gov
Data Coordinating Center for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) ContinuationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$8,663,508May 1, 2002June 30, 2028SHADE, DAVID Mreporter.nih.gov
dkNET Coordinating Unit: Harnessing the Power of AI and Data Science forCollaborative Discovery and Sharing in the DK CommunityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$8,645,871December 1, 2012February 28, 2029GRETHE, JEFFREY S.reporter.nih.gov
Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. Coli Infection (HIKO STEC): A Multinational, Embedded, Cluster, Crossover, Randomized TrialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,451,589September 17, 2021August 31, 2027FREEDMAN, STEPHEN BRADLEYreporter.nih.gov
Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed with Crohn's DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$8,401,766April 1, 2023March 31, 2028HYAMS, JEFFREY SAMUELreporter.nih.gov
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,239,326January 15, 2008November 30, 2027GRINSZTEJN, BEATRIZreporter.nih.gov
A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$8,184,774May 15, 2022April 30, 2027WANI, SACHINreporter.nih.gov
Human Biomimetics for Mucosal InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,059,968March 15, 2015May 31, 2027ESTES, MARY KOLBreporter.nih.gov
Precision IBD via genetics and genomics: integrating International and multi-omic datasets, expanding studies in diverse populations, and defining mechanisms of unmet clinical needs in IBDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,890,535September 30, 2002June 30, 2027CHO, JUDY H.reporter.nih.gov
Columbia Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,800,557September 1, 2002December 31, 2027PAJVANI, UTPALreporter.nih.gov
Advanced Development and Clinical Evaluation of an Entamoeba Histolytica VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$7,788,182September 21, 2018November 22, 2025FOX, CHRISTOPHERreporter.nih.gov
Stanford Tissue Mapping CenterNIHNational Human Genome Research Institute2022 to 2025$7,785,758September 23, 2022June 30, 2026SNYDER, MICHAEL P.reporter.nih.gov
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients (THINKER-NEXT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,767,541April 15, 2021March 31, 2027SCHAUBEL, DOUGLAS EARLreporter.nih.gov
Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeNIHNational Cancer Institute2022 to 2025$7,696,898September 20, 2022August 31, 2027GRADY, WILLIAM MALLORYreporter.nih.gov
Base Title: PREVENT Preclinical Drug Development Program: Preclinical Efficacy and Intermediate Endpoint BiomarkersTask Order Title: Colorectal Cancer (CRC) Prevention by TPST-1495 in PIRC rat modNIHNational Cancer Institute2021 to 2023$7,628,615September 11, 2023September 10, 2026RAO, CHINTHALAPALLYreporter.nih.gov
Early Phase Clinical Cancer Prevention ConsortiumNIHNational Cancer Institute2021 to 2025$7,613,555July 7, 2020July 31, 2031SCHUETZE, SCOTT MICHAELreporter.nih.gov
Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$7,269,328March 15, 2023February 29, 2028DULAI, PARAMBIR SINGHreporter.nih.gov
Identifying Immune and Epithelial Network Signatures in Very Early Onset Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$7,187,152September 15, 2020June 30, 2026SNAPPER, SCOTT Breporter.nih.gov
Northwestern Cancer Prevention ConsortiumNIHNational Cancer Institute2021 to 2025$7,062,222September 3, 2019July 31, 2031KHAN, SEEMA AHSANreporter.nih.gov
Systems Biology of Early Atopy (SUNBEAM) Analysis and Bioinformatics CenterNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$7,049,932December 8, 2022November 30, 2028BUNYAVANICH, SUPINDAreporter.nih.gov
iCAN PREVENT: MD Anderson International Cancer Prevention Clinical Trials ConsortiumNIHNational Cancer Institute2021 to 2025$7,046,172August 15, 2019July 31, 2031VILAR SANCHEZ, EDUARDOreporter.nih.gov
Personalized prime editing as a platform for hepatic inborn errors of metabolismNIHNational Center for Advancing Translational Sciences2024 to 2025$6,886,793September 20, 2024August 31, 2028AHRENS-NICKLAS, REBECCA CLAREreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,882,445September 29, 2025September 28, 2026WACTAWSKI-WENDE, JEANreporter.nih.gov
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug TourismNIHNational Institute on Drug Abuse2021 to 2024$6,868,774April 1, 2020January 31, 2026STRATHDEE, STEFFANIE A.reporter.nih.gov
MIST Early Career Scholar Awards in Mucosal ImmunologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,835,591July 25, 2011June 30, 2026ARTIS, DAVIDreporter.nih.gov
Subcutaneous Drug Development for Portal Hypertension AscitesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,758,500September 22, 2014July 31, 2027CASTILLO, GERARDO M.reporter.nih.gov
The oral environment in food allergy development (ONEIDA)NIHNational Institute of Allergy and Infectious Diseases2025$6,732,986August 1, 2025June 30, 2029BUNYAVANICH, SUPINDAreporter.nih.gov
California-Mexico-Puerto Rico Partnership (CAMPO) Center for Prevention of HPV-related Cancer in HIV+ PopulationsNIHNational Cancer Institute2021 to 2025$6,605,241September 12, 2019July 31, 2026PALEFSKY, JOEL MICHAELreporter.nih.gov
Integrated Epithelial and Muscosal BiologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,598,874September 1, 1997June 16, 2026LENCER, WAYNE Ireporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,534,889September 29, 2025September 28, 2026STEFANICK, MARCIAreporter.nih.gov
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,503,998August 14, 2020May 31, 2027NADEAU, KARI C.reporter.nih.gov
Novel therapy for alcoholic liver disease-associated hepatorenal syndromeNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$6,485,223September 25, 2021August 31, 2027SUBRAMANIAN, MANIreporter.nih.gov
Yale Liver CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,469,647September 30, 1997June 16, 2026NATHANSON, MICHAEL Hreporter.nih.gov
Decoding mechanisms underlying metabolic dysregulation in obesity and digestive cancer riskNIHNational Cancer Institute2022 to 2025$6,443,697September 20, 2022August 31, 2027TOBIAS, DEIRDRE KAYreporter.nih.gov
The Cleveland Digestive Diseases Research Core Center (DDRCC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,425,666February 15, 2015August 31, 2030COMINELLI, FABIOreporter.nih.gov
Molecular and Cellular Basis for Digestive DiseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,382,456June 15, 2002May 31, 2027PEEK, RICHARD M.reporter.nih.gov
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationNIHNational Institute on Aging2021 to 2025$6,330,805June 15, 2018May 31, 2028LAI, JENNIFER C.reporter.nih.gov
Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,330,175February 4, 2021January 31, 2026KAPPE, STEFAN HIreporter.nih.gov
Mechanisms of Fecal Microbiota Transplant Protection from Recurrent C. difficileNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,326,957July 24, 2020June 30, 2029PETRI, WILLIAM Areporter.nih.gov
The HIV and Alcohol Research center focused on Polypharmacy (HARP)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$6,323,238September 10, 2021August 31, 2026JUSTICE, AMY CAROLINEreporter.nih.gov
BASE TITLE: PREVENT PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY AND INTERMEDIATE ENDPOINT BIOMAKERSTASK ORDER TITLE: VACCINES AGAINST FUSOBACTERIUM FOR FAP-AND LYNCH SYNDROME-ASSOCIANIHNational Cancer Institute2022 to 2024$6,227,249June 15, 2022May 15, 2025CLAPPER, MARGIE L.reporter.nih.gov
Pittsburgh Liver Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,209,773July 1, 2019March 31, 2029MONGA, SATDARSHAN SINGHreporter.nih.gov
INSPPIRE: Using the natural history of pediatric chronic pancreatitis to identify disease predictors and design therapiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,195,043September 28, 2015June 30, 2030UC, ALIYEreporter.nih.gov
INSPIRE (INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients): The INSPIRE-ASP Trial for Intra-Abdominal and Skin and Soft Tissue InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,161,229June 19, 2020May 31, 2026PLATT, RICHARDreporter.nih.gov
Ancillary Studies of NAFLD and NASH in HIV infected AdultsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,132,391March 21, 2020January 31, 2026CHALASANI, NAGA Preporter.nih.gov
Host and microbial basis of human ulcerative colitis and pouchitis: Identification, role, mechanisms, and resource development of host susceptibility and pathobiont factorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$6,122,586September 1, 2019May 31, 2025CHANG, EUGENE Breporter.nih.gov
Optimizing Colorectal Cancer Screening PREcision and Outcomes in CommunIty-baSEd Populations (PRECISE)NIHNational Cancer Institute2021 to 2023$6,108,355April 15, 2018March 31, 2025CORLEY, DOUGLAS ALLENreporter.nih.gov
Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,096,518August 1, 2007May 31, 2027DENSON, LEE ARMISTEADreporter.nih.gov
PGpR2 Year 3 Supplement for the Scientific Data Research Center (SDRC) of the GpCRC 4NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,054,841May 1, 2006July 31, 2027SHADE, DAVID Mreporter.nih.gov
Johns Hopkins HIV Clinical CohortNIHNational Institute on Drug Abuse2021 to 2024$5,955,256July 1, 2014March 31, 2026MOORE, RICHARD DOUGLASreporter.nih.gov
Partnership for Prevention of HPV-Associated Cancers in People Living with HIV: Brazil, Mexico, and Puerto RicoNIHNational Cancer Institute2021 to 2025$5,948,066September 20, 2019July 31, 2026ELLSWORTH, GRANT B.reporter.nih.gov
Spatial and temporal resolution to dissect cellular circuits controlling intestinal physiology, immunity, and inflammatory pathologiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$5,934,972August 1, 2023May 31, 2028XAVIER, RAMNIK Jreporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,882,740August 26, 2021May 31, 2028LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
Identifying Microbial, Epithelial and Immune Cell Interactions that Mediate Mucosal Homeostasis and Determine IBD PhenotypesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$5,810,225September 19, 2013June 30, 2025SARTOR, RYAN Breporter.nih.gov
Sjögren’s Team for Accelerating Medicines Partnership (STAMP)NIHNational Institute of Dental & Craniofacial Research2022 to 2025$5,801,518March 7, 2022December 31, 2026SHIBOSKI, CAROLINE HELENEreporter.nih.gov
Host-environment interactions in the pathophysiology of digestive diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$5,753,874March 1, 2000July 31, 2030DAVIDSON, NICHOLAS O.reporter.nih.gov
Rational design and efficacy testing of vaccines against HCVNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,737,237May 5, 2022April 30, 2027FUERST, THOMAS Rreporter.nih.gov
Histidine phosphorylation as a new target for cancer therapyNIHNational Cancer Institute2021 to 2025$5,690,698September 18, 2019August 31, 2026HUNTER, TONY R.reporter.nih.gov
Improvements to the Regional Biocontainment Research Facilities at the University of MissouriNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$5,667,997September 23, 2021February 28, 2025LORSON, CHRISTIAN L.reporter.nih.gov
Food Allergy Management and Outcomes Related to Racial/Ethnic Differences from Infancy through Adolescence: The FORWARD StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,583,217May 11, 2017April 30, 2027GUPTA, RUCHI Sreporter.nih.gov
The role of stem cells and the microenvironment in gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$5,569,272January 7, 2016August 31, 2030WANG, TIMOTHY CRAGINreporter.nih.gov
MUSC Digestive Disease Research Core CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$5,554,374April 15, 2020August 31, 2030ROCKEY, DON C.reporter.nih.gov
Cervical, Anal & Oral HPV Persistence/Adolescent GirlsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,549,203May 15, 2007January 31, 2028DIAZ, ANGELAreporter.nih.gov
Effects of Intermittent Energy Restriction on Intra-Abdominal Fat and the Gut Microbiome: A Randomized TrialNIHNational Cancer Institute2021 to 2025$5,478,236September 22, 2021August 31, 2026LE MARCHAND, LOICreporter.nih.gov
Determinants of inception of inflammation in inflammatory bowel diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$5,397,834August 24, 2021May 31, 2027ANANTHAKRISHNAN, ASHWIN Nreporter.nih.gov
2/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health CenterNIHNational Cancer Institute2021 to 2025$5,355,395September 17, 2018August 31, 2028WILKIE, DIANA Jreporter.nih.gov
Chicago Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,330,849February 1, 2007November 30, 2027ACHENBACH, CHAD Jreporter.nih.gov
Cell plasticity in the origin of gastric carcinogenesisNIHNational Cancer Institute2022 to 2025$5,262,457September 1, 2025August 31, 2027CHOI, EUNYOUNGreporter.nih.gov
Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancerNIHNational Cancer Institute2021 to 2025$5,241,422July 21, 2020June 30, 2027KANNEGANTI, THIRUMALA-DEVIreporter.nih.gov
Comparative Modeling of Effective Policies for Colorectal Cancer ControlNIHNational Cancer Institute2021 to 2025$5,238,594July 1, 2025August 31, 2026ZAUBER, ANN GRAHAMreporter.nih.gov
Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$5,235,383September 18, 2019June 30, 2025WANG, DAVIDreporter.nih.gov
Skin microbes and development of allergic diseaseNIHNational Institute of Allergy and Infectious Diseases2025$5,176,858September 5, 2025August 31, 2029GALLO, RICHARD Lreporter.nih.gov
A Randomized Controlled Trial of Prophylaxis with Direct-acting Antivirals for Kidney Transplantation from Hepatitis C virus-infected donor to Uninfected Recipients (PREVENT-HCV)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,162,956March 25, 2022February 28, 2027DURAND, CHRISTINE MARIEreporter.nih.gov
A Multimodal 3D Atlas of Colorectal Cancer Across Ages of OnsetNIHNational Cancer Institute2024 to 2025$5,159,940September 1, 2024August 31, 2029LAU, KEN Sreporter.nih.gov
Center for Gastric Pre-Cancer Atlas of Multidimensional Evolution in 3D (GAME3D)NIHNational Cancer Institute2024 to 2025$5,158,661September 1, 2024August 31, 2029WANG, LINGHUAreporter.nih.gov
High-throughput proteomics using submicroliter amounts of plasma for comprehensive assessment of the immune statusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,147,391April 9, 2020March 31, 2026STEEN, HANNOreporter.nih.gov
Fecal Microbiota Transplantation and Fiber for the Treatment of Graft-versus-host Disease After Hematopoietic Cell TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$5,128,451September 1, 2023June 30, 2027FREDRICKS, DAVID NEALreporter.nih.gov
Drug Induced Liver Injury Network Data Coordinating CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$5,081,421September 30, 2003July 31, 2028BARNHART, HUIMAN Xreporter.nih.gov
An atlas of pancreatic tumorigenesis in the context of altered DNA repair occurring in high-risk individualsNIHNational Cancer Institute2024 to 2025$5,050,023September 1, 2024August 31, 2029SEARS, ROSALIE Creporter.nih.gov
Molecular Mechanism of Mammalian DNA Excision Repair and the Circadian ClockNIHNational Institute of General Medical Sciences2021 to 2025$5,040,955April 1, 2016August 31, 2027SANCAR, AZIZreporter.nih.gov
Mucus-degrading intestinal bacteria and toxicities of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,032,505September 21, 2024July 31, 2029JENQ, ROBERTreporter.nih.gov
Utility of Random Biopsies in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$5,031,513July 1, 2024June 30, 2029LEWIS, JAMES Dreporter.nih.gov
Pancreatic Cancer Detection ConsortiumNIHNational Cancer Institute2021 to 2025$5,023,372May 1, 2017August 31, 2027HOLLINGSWORTH, MICHAEL A.reporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$5,000,825September 29, 2025September 28, 2026JACKSON, REBECCAreporter.nih.gov
Gastroesophageal junction stem cells as the origin of Barretts esophagus and cancerNIHNational Cancer Institute2022 to 2025$4,948,268September 1, 2025August 31, 2027WANG, TIMOTHY CRAGINreporter.nih.gov
Bacteriophage-based approach for managing Shigella infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,946,719May 5, 2020April 30, 2026SULAKVELIDZE, ALEXANDERreporter.nih.gov
Reprogramming the Tumor-Immune Interface in Oral CancerNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,940,407September 8, 2020June 30, 2028SUNWOO, JOHN Breporter.nih.gov
Dose-response of aerobic training during total neoadjuvant therapy for locally advanced rectal cancerNIHNational Cancer Institute2022 to 2025$4,937,681May 6, 2022April 30, 2027SCOTT, JESSICAreporter.nih.gov
Targeting the MYC Pathway for the Treatment of CancerNIHNational Cancer Institute2021 to 2025$4,931,456September 8, 2020August 31, 2027FELSHER, DEAN Wreporter.nih.gov
Intervention to Reduce Early (Peanut) Allergy in Children (iREACH)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,923,573July 24, 2019June 30, 2025GUPTA, RUCHI Sreporter.nih.gov
Precision Prevention Research ProgramNIHNational Cancer Institute2021 to 2025$4,849,798September 1, 2020August 31, 2027CHAN, ANDREW Treporter.nih.gov
Predicting Pancreatic Ductal Adenocarcinoma (PDAC) Through Artificial Intelligence Analysis of Pre-Diagnostic CT ImagesNIHNational Cancer Institute2021 to 2025$4,827,743September 1, 2021August 31, 2026LI, DEBIAOreporter.nih.gov
Great Lakes New England Clinical Validation CenterNIHNational Cancer Institute2022 to 2025$4,820,800May 15, 2000August 31, 2027RICCIARDIELLO, LUIGIreporter.nih.gov
Endosomal mechanisms signaling oral cancer painNIHNational Institute of Dental & Craniofacial Research2023$4,820,611September 19, 2023August 31, 2026SCHMIDT, BRIAN Lreporter.nih.gov
Establishing patient-derived iPSCs as a platform for discovery research in NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$4,780,391June 1, 2023March 31, 2028MAHER, JACQUELYN J.reporter.nih.gov
Metabolic Influences on Complex Tumor NeighborhoodsNIHNational Cancer Institute2021 to 2025$4,722,150August 1, 2017July 31, 2030SIMON, M. CELESTEreporter.nih.gov
Defining mechanisms driving salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,717,861September 18, 2018June 30, 2026KNOX, SARAH MONICAreporter.nih.gov
Development of Non-Human Primate Models to Assess Immunological Mechanisms and Antigenic Targets of Protective Sporozoite (SPZ) Vaccines and Establish Superior Efficacy of Next Generation SPZ vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,717,265April 1, 2021March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Targeting hepatic stellate cell metabolism to treat steatotic liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,674,973April 1, 2015August 31, 2029FINCK, BRIAN Nreporter.nih.gov
Integrating Addiction and Infectious Diseases Services into Primary Care in Rural SettingsNIHNational Institute on Drug Abuse2021 to 2025$4,664,222August 1, 2021May 31, 2027ALTICE, FREDERICK LEWISreporter.nih.gov
Live-cell Activity Architecture in CancerNIHNational Cancer Institute2021 to 2025$4,655,641August 1, 2015July 31, 2029ZHANG, JINreporter.nih.gov
Effects of Time-restricted Eating versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers among Adults with ObesityNIHNational Cancer Institute2021 to 2025$4,635,563September 1, 2021August 31, 2027TUSSING-HUMPHREYS, LISAreporter.nih.gov
IgE antibodies to the mammalian oligosaccharide galactose-alpha-1, 3-galactose (alpha-gal): immunology, epidemiology and relevance to allergic and inflammatory diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,621,686July 1, 1984May 31, 2028PLATTS-MILLS, THOMAS A.reporter.nih.gov
Early to Late Events in Colorectal Neoplasia: Basic Biology to Clinical ImplementationNIHNational Cancer Institute2021 to 2025$4,608,771April 1, 2017July 31, 2031COFFEY, ROBERT J.reporter.nih.gov
Non-alcoholic Fatty Liver Disease and Cardiovascular Disease in Hispanics/LatinosNIHNational Heart, Lung, and Blood Institute2021 to 2022$4,589,716September 1, 2019August 31, 2024KIZER, JORGE Rreporter.nih.gov
Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes MellitusNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,582,323September 20, 2018July 31, 2024STAHL, ANDREASreporter.nih.gov
Tissue factor-dependent coagulation in thrombosis and immune responsesNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,577,076February 1, 2021January 31, 2028MACKMAN, NIGELreporter.nih.gov
Mechanisms underlying gastric intestinal metaplasia and carcinogenesisNIHNational Cancer Institute2022 to 2025$4,560,310September 20, 2022August 31, 2027RUSTGI, ANIL Kreporter.nih.gov
Coordinate Regulation of Virulence in Vibrio CholeraeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,541,366July 1, 1981March 31, 2029MEKALANOS, JOHN JOSEPHreporter.nih.gov
Intracellular Innate Immune Receptors in Cancer Suppression and ImmunotherapyNIHNational Cancer Institute2021 to 2025$4,541,273September 17, 2019August 31, 2026TING, JENNY Preporter.nih.gov
Support for the Central Data Collection Center (CDCC)NIHNational Cancer Institute2021 to 2025$4,460,745February 27, 2021February 26, 2025MATHEW, SUNITHAreporter.nih.gov
Early Pathogenesis of Cystic Fibrosis Related DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$4,452,977April 30, 2021March 31, 2024ENGELHARDT, JOHN Freporter.nih.gov
Increasing Access to Hepatitis C Treatment in Opioid Endemic Rural Areas: the Kentucky Viral Hepatitis Treatment (KeY Treat) StudyNIHNational Institute on Drug Abuse2021 to 2023$4,371,481September 30, 2018July 31, 2025HAVENS, JENNIFER Rreporter.nih.gov
Human Microphysiology Systems Disease Model of Type 2 Diabetes Starting with Liver and pancreatic IsletsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,324,679September 20, 2018July 31, 2023TAYLOR, D. LANSINGreporter.nih.gov
Porphyrias ConsortiumNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$4,280,404September 30, 2009June 30, 2025DESNICK, ROBERT Jreporter.nih.gov
The effectiveness of screening women with lower genital tract neoplasia or cancers for anal cancer precursorsNIHNational Cancer Institute2021 to 2025$4,277,018September 1, 2021August 31, 2027SIGEL, KEITH MAGNUSreporter.nih.gov
Live cell reporters of genetic changes in stiff vs soft surroundings - Causes & ConsequencesNIHNational Cancer Institute2021 to 2025$4,251,467April 1, 2021March 31, 2026DISCHER, DENNIS E.reporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$4,249,024September 29, 2025September 28, 2026VITOLINS, MARAreporter.nih.gov
Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and MorbidityNIHNational Institute of Environmental Health Sciences2021 to 2025$4,237,518August 1, 2019May 31, 2027XIE, WENreporter.nih.gov
Cytokine regulation of mucosal inflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,234,402June 6, 2019June 30, 2029SONNENBERG, GREGORY Freporter.nih.gov
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,204,220May 15, 2015June 30, 2030FLEXNER, CHARLES W.reporter.nih.gov
Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$4,185,542September 15, 2023June 30, 2028LEBWOHL, BENJAMINreporter.nih.gov
Integrating HCV services into HIV programs for PWID in IndiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,184,487July 8, 2019June 30, 2025MEHTA, SHRUTI Hreporter.nih.gov
Leveraging Omics and Electronic Health Records Data to study Colorectal Adenoma genetics and Drug RepurposingNIHNational Cancer Institute2025$4,174,595September 10, 2025August 31, 2029GUO, XINGYIreporter.nih.gov
Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug DiscoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,163,372November 15, 2020October 31, 2026STAKER, BART LEEreporter.nih.gov
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and ModeratorsNIHNational Cancer Institute2021 to 2025$4,123,295June 15, 2021August 31, 2026FIGUEIREDO, JANE C.reporter.nih.gov
The role of CD40L in resistance to enteric infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,118,859August 17, 2021May 31, 2026HUNTER, CHRISTOPHER Areporter.nih.gov
Development of an oral liver-targeted prime-and-trap malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,104,491December 1, 2020November 30, 2026MURPHY, SEAN Creporter.nih.gov
Altered metabolism and machine learning for pancreatic cancer early detectionNIHNational Cancer Institute2021 to 2025$4,100,528September 16, 2022August 31, 2027WOLPIN, BRIAN MATTHEWreporter.nih.gov
The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targetsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$4,099,868September 21, 2021May 31, 2026GORDON, JEFFREY Ireporter.nih.gov
Stromal modulation of pancreatic cancer malignant cell state and therapeutic sensitivityNIHNational Cancer Institute2022 to 2025$4,096,241September 19, 2022August 31, 2027HAHN, WILLIAM C.reporter.nih.gov
CRC-HUB-SPOKE: A ColoRectal Cancer screening Hub for Southern California community health centers.NIHNational Cancer Institute2021 to 2023$4,080,149September 19, 2019August 31, 2025MARTINEZ, MARIA ELENAreporter.nih.gov
Initiation of Diffuse and Intestinal Non-Cardia Gastric CancerNIHNational Cancer Institute2022 to 2025$4,080,056September 1, 2025August 31, 2027RYEOM, SANDRAreporter.nih.gov
RADx Innovation Funnel for Hepatitis B Diagnostics - Coordination CenterNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,074,004September 30, 2024September 29, 2026SCHACHTER, STEVEN C.reporter.nih.gov
Exosome-based microRNA biomarkers for Non-invasive and Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$4,072,882September 1, 2017July 31, 2028GOEL, AJAYreporter.nih.gov
Optimization of Lead BKIs for Cryptosporidiosis TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,065,300January 1, 2021December 31, 2026VAN VOORHIS, WESLEY Creporter.nih.gov
Comparative modeling of gastric cancer health drivers and prevention in the US and globallyNIHNational Cancer Institute2021 to 2025$4,054,972September 15, 2021August 31, 2026HUR, CHINreporter.nih.gov
A personalized approach using hypoxia resolution to guide curative-intent radiation dose reduction to 30 Gy: A novel de-escalation paradigm for HPV-associated oropharynx cancersNIHNational Cancer Institute2021 to 2025$4,028,888March 3, 2020March 31, 2030LEE, NANCY Yreporter.nih.gov
Improving Survival in Oral Cancer by Disruption of Tumor ProgressionNIHNational Institute of Dental & Craniofacial Research2021 to 2024$4,021,748September 14, 2017June 30, 2025D'SILVA, NISHA Jreporter.nih.gov
Disambiguating natural aging from Alzheimer's disease through changes in oral neuromechanicsNIHNational Institute on Aging2022 to 2024$4,016,586September 15, 2020May 31, 2026ARCE-MCSHANE, FRITZIE ISIPreporter.nih.gov
Implantable iontophoresis chemotherapy delivery device for direct infusion ofgemcitabine into pancreatic adenocarcinoma: Device development and First-in-Human clinical trialNIHNational Cancer Institute2021 to 2022$4,000,000September 17, 2017July 31, 2024DAUNCH, WILLIAM ANDREWreporter.nih.gov
Consortium on Intestinal Regeneration and Fetal Reversion: from Atlas to TherapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$4,000,000September 1, 2024June 30, 2029KLEIN, OPHIR Dreporter.nih.gov
Commercializing CivaSheet for Pancreatic Cancer PatientsNIHNational Cancer Institute2023 to 2025$3,999,206September 13, 2016June 30, 2026PEREZ, KRISTYreporter.nih.gov
Validation of biomarkers for risk prediction and early diagnosis of Pancreatic AdenocarcinomaNIHNational Cancer Institute2021 to 2025$3,998,452May 17, 2016March 31, 2028BRAND, RANDALLreporter.nih.gov
Development of a protein drug for pancreatic cancer treatmentNIHNational Cancer Institute2022 to 2024$3,994,217September 26, 2017January 31, 2025LIU, ZHI-RENreporter.nih.gov
A novel diagnostic Kit for Hepatocellular CarcinomaNIHNational Cancer Institute2021 to 2023$3,993,675September 1, 2012August 31, 2025LU, XUANYONGreporter.nih.gov
Identifying Metabolic Dependencies of Pancreatic CancersNIHNational Cancer Institute2021 to 2024$3,975,118August 1, 2018July 31, 2025KIMMELMAN, ALECreporter.nih.gov
Is Obesity an Infectious Disease?: Gut bacterial and fungal translocation as an underappreciated driver of visceral adipose expansion.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,971,090September 30, 2021June 30, 2026DEVKOTA, SUZANNEreporter.nih.gov
IL-10NanoCap® for Therapy of Familial Adenomatous PolyposisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,969,244March 7, 2019March 31, 2026AUCI, DOMINICKreporter.nih.gov
Ceramides as novel drivers of metabolic dysfunction and colorectal cancerNIHNational Cancer Institute2022 to 2025$3,957,452September 2, 2022August 31, 2027PLAYDON, MARY CHRISTINEreporter.nih.gov
Targeting HB-EGF and trigeminal EGFR for oral cancer pain and opioid toleranceNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,950,748September 19, 2022September 18, 2027YE, YIreporter.nih.gov
Gut barrier function in Alzheimer’s diseaseNIHNational Institute on Aging2021 to 2025$3,945,245February 15, 2021January 31, 2026BENDLIN, BARBARA BRIGITTAreporter.nih.gov
Molecular basis of bioelectronic medicineNIHNational Institute of General Medical Sciences2021 to 2025$3,937,630May 1, 2016April 30, 2027TRACEY, KEVIN Jreporter.nih.gov
Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHSNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,935,193February 1, 2022January 31, 2027XAVIER, RAMNIK Jreporter.nih.gov
Fibroblast Heterogeneity in Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,931,956August 10, 2021July 31, 2026TUVESON, DAVID Areporter.nih.gov
A systems immunology approach for predicting poor responses to Hepatitis B vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,925,255September 17, 2021August 31, 2026HERATI, RAMINreporter.nih.gov
Interrogating the Evolutionary Dynamics of Cancer for Clinical Benefit and ActionabilityNIHNational Cancer Institute2021 to 2024$3,915,629August 1, 2018July 31, 2025IACOBUZIO-DONAHUE, CHRISTINE Areporter.nih.gov
Next-generation human liver gene therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,896,814September 30, 2021June 30, 2027WILLENBRING, HOLGERreporter.nih.gov
Elucidation and targeting of paracrine cascades in PDACNIHNational Cancer Institute2022 to 2025$3,892,796September 1, 2022August 31, 2027OLIVE, KENNETH P.reporter.nih.gov
Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer.NIHNational Institute of Dental & Craniofacial Research2025$3,892,146September 1, 2025August 31, 2029LI, XINreporter.nih.gov
Dietary and synbiotic strategy to limit gut microbiome dysbiosis and protect against Clostridioides difficile infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,880,251April 23, 2021March 31, 2027LOZUPONE, CATHERINEreporter.nih.gov
HIV Persistence and Renewal in the Gastrointestinal, Genitourinary and Adipose TissuesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,879,562September 17, 2021July 31, 2026SMITH, DAVID MITCHELLreporter.nih.gov
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseNIHNational Institute on Drug Abuse2021 to 2025$3,865,844September 25, 2022January 31, 2029OWENS, DOUGLAS Kreporter.nih.gov
Development of small molecule inhibitors of metabolic enzymes as broad spectrum anthelmintic drugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,860,924March 11, 2021February 28, 2027MITREVA, MAKEDONKAreporter.nih.gov
Precision Risk Stratification and Screening for HCC among Patients with Indeterminate Liver NodulesNIHNational Cancer Institute2023 to 2025$3,858,633September 19, 2023August 31, 2028SINGAL, AMITreporter.nih.gov
Macrophage Polarization in Response to Infections and InflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,855,235September 22, 2020August 31, 2025GHOSH, PRADIPTAreporter.nih.gov
Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablationNIHNational Cancer Institute2022 to 2025$3,855,091September 22, 2022August 31, 2027MARKOWITZ, SANFORD D.reporter.nih.gov
Developing broad-spectrum therapeutics against C. difficile toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,852,231February 11, 2021January 31, 2027JIN, RONGSHENGreporter.nih.gov
Mechanisms and pathophysiologic impact of claudin-2 modulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,845,865September 29, 2001June 30, 2028TURNER, JERROLD R.reporter.nih.gov
Mechanisms of protection against shigellosis in childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,843,317June 9, 2022May 31, 2027PASETTI, MARCELA Freporter.nih.gov
A Rhesus Macaque Model of HIV and HBV co-infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,842,980March 20, 2021February 28, 2026BURWITZ, BENJAMIN Jreporter.nih.gov
Molecular mechanisms underlying HIV related intestinal epithelial barrier dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,842,606August 1, 2021December 31, 2026PARKOS, CHARLES Areporter.nih.gov
The UCLA Center in Early Detection of Liver CancerNIHNational Cancer Institute2021 to 2025$3,825,539September 17, 2018August 31, 2028ZHOU, XIANGHONG JASMINEreporter.nih.gov
Functional profiling of OSP-specific and other antibodies during shigella infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,818,268September 22, 2020August 31, 2030RYAN, EDWARD T.reporter.nih.gov
GEMS: Genomic approach to connecting Elevated germline Mutation rates with male infertility and Somatic healthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,803,952September 1, 2021May 31, 2027HOTALING, JAMESreporter.nih.gov
B cell memory in human food allergyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,793,314June 9, 2021December 31, 2026CUROTTO DE LAFAILLE, MARIA Areporter.nih.gov
Integrating genomics and the protein interactome for HPV+ head and neck cancer therapyNIHNational Cancer Institute2021 to 2024$3,779,781August 15, 2018July 31, 2025GRANDIS, JENNIFER RUBINreporter.nih.gov
Columbus NCORP RFA-CA-18-016NIHNational Cancer Institute2021 to 2025$3,771,688August 1, 2014July 31, 2026RAJAGOPALAN, MALOLAN Sreporter.nih.gov
Optimization of a remote intervention to improve nutrition and physical activity in colorectal cancer survivorsNIHNational Cancer Institute2021 to 2025$3,771,145December 10, 2020November 30, 2025VAN BLARIGAN, ERIN LYNNreporter.nih.gov
Human natural killer cells: Advancing biology and clinical applicationsNIHNational Cancer Institute2021 to 2025$3,769,374July 21, 2017June 30, 2032CALIGIURI, MICHAEL Areporter.nih.gov
Mayo Clinic Prospective Resource for Biomarker Validation and Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,767,699July 15, 2016August 31, 2027MAJUMDER, SHOUNAKreporter.nih.gov
Defining the lymphatic basis of protein losing enteropathy after Fontan palliation or inflammatory gut diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,759,375September 30, 2021June 30, 2027RANDOLPH, GWENDALYN Jreporter.nih.gov
O-Specific Polysaccharide Responses and CholeraNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,758,033August 7, 2013March 31, 2030RYAN, EDWARD T.reporter.nih.gov
Spatio-temporal Methods for Surveillance of the Opioid SyndemicNIHNational Institute on Drug Abuse2021 to 2025$3,748,657September 1, 2025August 31, 2029KLINE, DAVID Mreporter.nih.gov
Immunity to CryptosporidiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,739,027January 1, 2020December 31, 2029HUNTER, CHRISTOPHER Areporter.nih.gov
Rational Integration of Polygenic Risk Scores (RIPS)NIHNational Human Genome Research Institute2022 to 2025$3,737,256March 10, 2022February 28, 2027PETERSON, JOSEPH F.reporter.nih.gov
Clinical Validation Center for Hepatocellular CarcinomaNIHNational Cancer Institute2022 to 2025$3,730,583August 3, 2022July 31, 2027SINGAL, AMITreporter.nih.gov
Enteric Pathogen Force of Infection among Children using SerologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,719,600July 1, 2021June 30, 2027ARNOLD, BENJAMIN Freporter.nih.gov
Pathogenesis of youth onset pre-diabetes and Type 2 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,716,431September 22, 2016July 31, 2026CAPRIO, SONIAreporter.nih.gov
HAWAII CLINICAL RESEARCH NETWORK FOR HEALTH EQUITYNIHNational Institute on Minority Health and Health Disparities2024 to 2025$3,711,764September 24, 2022November 30, 2027SHIKUMA, CECILIA M.reporter.nih.gov
Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,704,381March 19, 2021February 28, 2027AMARASINGHE, GAYA K.reporter.nih.gov
Conduct Synthesis and Acquire Batches of Compounds for Subsequent Biological In Vitro and In Vivo TestingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,702,250April 1, 2024March 31, 2025MIDDLETON, MARKreporter.nih.gov
Gastroschisis Outcomes of Delivery (GOOD) StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,695,902April 13, 2021March 31, 2027WAGNER, AMY Jreporter.nih.gov
Restoring Central Regulation of Glucose Production in Type 2 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,695,446June 15, 2006April 30, 2027HAWKINS, MEREDITH Areporter.nih.gov
THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATIONNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,689,371July 16, 2012May 31, 2027BAKER, OLGA JULIANAreporter.nih.gov
Novel Determinants for Progression of Non-Alcoholic Fatty Liver Disease to Hepatocellular Carcinoma and Other Health OutcomesNIHNational Cancer Institute2021 to 2025$3,678,371September 7, 2021August 31, 2026YUAN, JIAN-MINreporter.nih.gov
Look inward: brainstem and cortical circuits for boosting interoceptive attentionNIHNational Center for Complementary & Integrative Health2021 to 2023$3,675,000September 30, 2019July 31, 2025ANDERMANN, MARK Lreporter.nih.gov
Blood-Based Testing for Advanced AdenomaNIHNational Cancer Institute2022 to 2025$3,665,539September 12, 2022February 29, 2028SCHOEN, ROBERT E.reporter.nih.gov
Enhancing immune regulation in gene therapy for hemophiliaNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,664,714July 1, 2016June 30, 2029HERZOG, ROLAND W.reporter.nih.gov
Studying factors controlling cancer progression and immune recognition in mouse modelsNIHNational Cancer Institute2022 to 2025$3,664,660September 20, 2022August 31, 2029JACKS, TYLER E.reporter.nih.gov
Using ex vivo, in vivo models and patient mutations to interrogate pancreatic exocrine-endocrine cross talkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,664,508September 20, 2022June 30, 2027KULKARNI, ROHIT N.reporter.nih.gov
Effects of inflammaging on intestinal epithelial cells and aspirin chemoprevention.NIHNational Cancer Institute2021 to 2025$3,654,173April 5, 2021March 31, 2027CHAN, ANDREW Treporter.nih.gov
Trial of Statins for Chemoprevention in Hepatocellular CarcinomaNIHNational Cancer Institute2021 to 2025$3,646,155September 1, 2021August 31, 2027CHUNG, RAYMOND Treporter.nih.gov
Using markers to improve pancreatic cancer screening and surveillance: a multi-center studyNIHNational Cancer Institute2021 to 2025$3,641,472July 18, 2016August 31, 2027GOGGINS, MICHAEL G.reporter.nih.gov
Molecular strategies for early detection and targeting of cancerNIHNational Cancer Institute2022 to 2025$3,640,759August 12, 2015July 31, 2028REYA, TANNISHTHAreporter.nih.gov
Estrogen Administration for the Treatment of NASH in Postmenopausal WomenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,638,994August 1, 2021May 31, 2027MILLER, KAREN Kreporter.nih.gov
IND Enabling Studies and Manufacturing Scale Up of Human Placental Extract to Prevent Surgical Necrotizing EnterocolitisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,623,857July 2, 2020May 31, 2027BERGER, MICHAEL BENTLEYreporter.nih.gov
Clinical & Immunological Study of Treatment Withdrawal in E-Ag Negative Hepatitis BNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,618,437September 1, 2016June 30, 2026COOPER, STEWARTreporter.nih.gov
Research Training in Digestive DiseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,607,280July 1, 1976June 30, 2026CHUNG, RAYMOND Treporter.nih.gov
Role of the Epitranscriptome in CancerNIHNational Cancer Institute2021 to 2024$3,597,010August 1, 2019November 30, 2024GREGORY, RICHARD I.reporter.nih.gov
Mechanisms associated with flares and remission in colitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,593,722May 1, 2017May 31, 2026LIRA, SERGIO A.reporter.nih.gov
NIH: Spatial Models of Intrahepatic Hepatitis Virus Propagation in HumansNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,593,236February 7, 2022January 31, 2027RIBEIRO, RUY Mreporter.nih.gov
Type IV Protein Secretion in Helicobacter pyloriNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,592,685February 18, 2016March 31, 2027COVER, TIMOTHY Lreporter.nih.gov
Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Uncover Hidden BiologyNIHNational Cancer Institute2021 to 2025$3,589,331July 1, 2019August 31, 2026PERMUTH, JENNIFER Breporter.nih.gov
Targeting undruggable RAS for cancer treatmentNIHNational Cancer Institute2021 to 2024$3,589,157September 1, 2018August 31, 2025DER, CHANNING J.reporter.nih.gov
Genetics, Epigenetics, and Risk Prediction for Esophageal AdenocarcinomaNIHNational Cancer Institute2022 to 2025$3,588,780September 12, 2022August 31, 2027KOOPERBERG, CHARLES Lreporter.nih.gov
Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-RenewalNIHNational Cancer Institute2021 to 2025$3,585,446July 1, 2010June 30, 2027NAKAGAWA, MAYUMIreporter.nih.gov
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIVNIHNational Institute on Drug Abuse2022 to 2025$3,584,464June 15, 2022March 31, 2027ELLIS, RONALD J.reporter.nih.gov
Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of SwallowingNIHNational Institute on Aging2022 to 2025$3,572,615August 1, 2010July 31, 2027STEELE, CATRIONA MARGARETreporter.nih.gov
Effectiveness and implementation of a health system intervention to improve quality of cancer care for rural, underserved patientsNIHNational Cancer Institute2021 to 2025$3,568,895April 1, 2021March 31, 2027CHARLTON, MARY E.reporter.nih.gov
Circulating Biomarkers and Imaging for Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,563,506August 7, 2018July 31, 2029SEN, SUBRATAreporter.nih.gov
A Transdisciplinary Approach to Investigating Metabolic Dysregulation in Obese Parent and Child Dyads and Risk of Colorectal CancerNIHNational Cancer Institute2022 to 2025$3,558,479August 16, 2022July 31, 2028HEBERT, JAMES Rreporter.nih.gov
Assessing the effects of oral pre-exposure prophylaxis on pharmacokinetics of monoclonal and vaccine-induced antibodies among women vulnerable to HIV-1NIHNational Institute of Allergy and Infectious Diseases2025$3,554,273September 12, 2025August 31, 2029HUANG, YUNDAreporter.nih.gov
Bioactive Metabolites Modulate Immune-Related Adverse Events in Cancer ImmunotherapyNIHNational Cancer Institute2021 to 2025$3,549,010July 8, 2021February 28, 2027SHARMA, SONIAreporter.nih.gov
Interactions between neutrophils and cholangiocytes in alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,548,231September 25, 2021June 30, 2027NATHANSON, MICHAEL Hreporter.nih.gov
Preventing GVHD by inhibition of alloantigen presentation in the gutNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,543,040July 1, 2019June 30, 2027HILL, GEOFFREY ROGERreporter.nih.gov
Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported OutcomesNIHNational Center for Advancing Translational Sciences2021 to 2023$3,537,149April 20, 2020March 31, 2025SANDS, BRUCE Ereporter.nih.gov
University of California and UT Southwestern D-PDTCNIHNational Cancer Institute2023 to 2025$3,532,429August 1, 2023July 31, 2028CARVAJAL CARMONA, LUIS GUILLERMOreporter.nih.gov
Risk Stratification for and Early Detection of Liver CancerNIHNational Cancer Institute2021 to 2025$3,531,567September 13, 2018August 31, 2028KANWAL, FASIHAreporter.nih.gov
Targeting the Intestinal Mucosa and Microbiome to Prevent Neonatal Late-onset SepsisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,526,115August 1, 2021July 31, 2027WEAVER, CASEY Treporter.nih.gov
Impact of the COVID-19 pandemic on patient outcomes, telehealth care delivery, and treatment for unhealthy alcohol use in vulnerable patients with advanced liver disease across two healthcare systemsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,517,747June 1, 2021February 28, 2027KHALILI, MANDANAreporter.nih.gov
Acute/chronic limitations to transcriptional RNAi therapies for infectious and other liver diseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,515,317August 1, 2006July 31, 2026KAY, MARK Areporter.nih.gov
Control of intestinal innate immunity by the commensal microbiota in a model hostNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,511,902September 24, 2021August 31, 2027WATNICK, PAULA Ireporter.nih.gov
Structural and Mechanistic basis for RNA SilencingNIHNational Institute of General Medical Sciences2021 to 2025$3,507,599August 1, 2018July 31, 2028MACRAE, IAN JOHNreporter.nih.gov
Host-pathogen interactions in experimental choleraNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,506,027January 1, 1998May 31, 2027WALDOR, MATTHEW Kreporter.nih.gov
Clinical Center for Cholestatic Liver Disease in ChildrenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,505,921September 15, 2002May 31, 2029MIETHKE, ALEXANDERreporter.nih.gov
Analysis of the Metabolic Capabilities of Prokaryotic CellsNIHNational Institute of General Medical Sciences2021 to 2025$3,499,962March 1, 2019March 31, 2029ESCALANTE, JORGE Creporter.nih.gov
Variation in tumor-associated immune profiles and colorectal cancer outcomesNIHNational Cancer Institute2021 to 2025$3,497,316September 15, 2021August 31, 2027SCHMIT, STEPHANIE L.reporter.nih.gov
Biochemical and cellular mechanisms linking actin mutations to visceral myopathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,487,348September 28, 2021August 31, 2027HEUCKEROTH, ROBERT Oreporter.nih.gov
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,482,713August 14, 2020January 13, 2023NADEAU, KARI C.reporter.nih.gov
Soil epidemiology: a new tool for environmental surveillance of soil-transmitted helminth infections in endemic settings.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,480,159July 1, 2025June 30, 2027PICKERING, AMY J.reporter.nih.gov
Evaluation of Memory Responses and Biomarkers from a Phase IEnterotoxigenic Escherichia coli (ETEC) Intramuscular SubunitVaccine with dmLT AdjuvantNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,467,638September 24, 2021August 31, 2026NORTON, ELIZABETH Breporter.nih.gov
Role of Transglutaminase 2 in Celiac SprueNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,463,787September 20, 2003April 30, 2026KHOSLA, CHAITANreporter.nih.gov
Abbreviated MRI for HCC screening in cirrhotic patientsNIHNational Cancer Institute2021 to 2024$3,461,079June 19, 2020May 31, 2026TAOULI, BACHIRreporter.nih.gov
AcetaSTAT Validation and CommercializationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,458,961April 1, 2008March 31, 2026JAMES, LAURA Preporter.nih.gov
Innate Immune Defense Mechanisms in the IntestineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,458,283August 1, 2014November 30, 2026REINECKER, HANS-CHRISTIANreporter.nih.gov
A Phase 1-2 clinical program for the teatment of Microsatellite Stable Colorectal Cancer with the combination of SR-8541A, Botensilimab, and BalstilimabNIHNational Cancer Institute2022 to 2025$3,457,194August 14, 2025July 31, 2028KAADIGE, MOHAN RAOreporter.nih.gov
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,455,616February 11, 2020January 31, 2026ROBINSON-PAPP, JESSICAreporter.nih.gov
The MYC Transcription Factor Network and the Path to CancerNIHNational Cancer Institute2021 to 2024$3,449,610September 1, 2018August 31, 2025EISENMAN, ROBERT NEILreporter.nih.gov
Multi-modal Liquid Biopsy Early Assessment of Breast Cancer, Pancreatic Cancer, and Multiple MyelomaNIHNational Cancer Institute2023 to 2025$3,449,390September 18, 2023August 31, 2028KUHN, PETERreporter.nih.gov
Vibrio cholerae quorum sensing as an intestinal symbiosis factor in a model arthropod hostNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,444,100June 1, 2021June 8, 2026WATNICK, PAULA Ireporter.nih.gov
Development of MecVax, a Cross Protective Subunit Vaccine for ETECNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,440,502June 1, 2023May 31, 2028ZHANG, WEIPINGreporter.nih.gov
Improving radiolabeled imaging and targeting of HER2 positive EG cancers using lovastatinNIHNational Cancer Institute2021 to 2025$3,432,890December 1, 2020November 30, 2026LEWIS, JASON S.reporter.nih.gov
Clinical Research on Nonalcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,430,513September 15, 2002June 30, 2027LOOMBA, ROHITreporter.nih.gov
Chemical tools for developmental biologyNIHNational Institute of General Medical Sciences2021 to 2025$3,426,216April 1, 2018June 30, 2028CHEN, JAMES Kreporter.nih.gov
Training in Pediatric Gastroenterology, Hepatology, and NutritionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,415,797December 1, 1983April 30, 2029SNAPPER, SCOTT Breporter.nih.gov
Optimizing Lung Cancer Screening in Cancer SurvivorsNIHNational Cancer Institute2021 to 2025$3,415,788July 15, 2021June 30, 2027WISNIVESKY, JUAN Preporter.nih.gov
Human Genetic determinants of HBV recoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,412,348September 30, 1999December 31, 2026THOMAS, DAVID Lreporter.nih.gov
Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST)NIHNational Institute of Allergy and Infectious Diseases2025$3,411,692September 24, 2025August 31, 2030NAGGIE, SUSANNAreporter.nih.gov
Characterization of Mucosal LymphocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,410,819September 30, 1992June 30, 2029BLUMBERG, RICHARD Sreporter.nih.gov
Microbiota-derived metabolites and the regulation of host immunity and inflammationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,409,847June 14, 2022May 31, 2027ARTIS, DAVIDreporter.nih.gov
Regulation of TLR signaling, Inflammation and Antigen Presentation by VPS33BNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,409,595July 1, 2021June 30, 2026PASARE, CHANDRASHEKHARreporter.nih.gov
Uncovering the parasite and host determinants of Plasmodium vivax hypnozoite formation and development using single cell sequencing and human liver-chimeric miceNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,399,010February 7, 2022January 31, 2027VAUGHAN, ASHLEY Mreporter.nih.gov
Characterizing Vancomycin-Resistant C. difficile Strains at Two Geographically Distinct LocationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,395,135April 1, 2021March 31, 2027DARKOH, CHARLESreporter.nih.gov
Remediating fibrosis for salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,392,837April 1, 2019March 31, 2029LARSEN, MELINDAreporter.nih.gov
Biology and Function of Exosomes in CancerNIHNational Cancer Institute2022 to 2025$3,385,880September 1, 2022August 31, 2029KALLURI, RAGHUreporter.nih.gov
Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veteransNIHNational Institute on Drug Abuse2021 to 2025$3,379,762September 30, 2021July 31, 2027BENNETT, ALEXANDER Sreporter.nih.gov
Exploiting and enhancing IgE-binding epitopes of the 2S albumins of peanuts and tree nutsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,375,729September 17, 2021August 31, 2027DRESKIN, STEPHEN Creporter.nih.gov
Defining the impact of type 1 cytokine signaling on STAT-mediated epithelial reprogramming and barrier dysfunction in eosinophilic esophagitisNIHNational Institute of Allergy and Infectious Diseases2025$3,375,359July 9, 2025June 30, 2029RUFFNER, MELANIE Areporter.nih.gov
Commensal control of C. difficile virulenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,372,908February 1, 2021January 31, 2027BRY, LYNNreporter.nih.gov
Integration of genomics and transcriptomics to investigate biological pathways in very early onset IBDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,353,628July 1, 2021April 30, 2027KELSEN, JUDITH RACHELreporter.nih.gov
AN INTEGRATED PLATFORM FOR NOVEL PERSONALIZED LIVER CANCER THERAPEUTICSNIHNational Cancer Institute2021 to 2025$3,349,717July 1, 2021June 30, 2027GUCCIONE, ERNESTOreporter.nih.gov
Promoting remote and secondary risk prevention services in rural settingsNIHNational Institute on Drug Abuse2022 to 2025$3,349,340September 30, 2022July 31, 2027PHO, MAI TUYETreporter.nih.gov
Developing and Testing a Digital Toolkit to Improve Colorectal Cancer Screening Rates in Federally Qualified Health CentersNIHNational Cancer Institute2021 to 2025$3,348,072April 1, 2021March 31, 2027MILLER, SARAH Jreporter.nih.gov
Gamma delta T cells promote inflammation in aviremic HIV infection and normal agingNIHNational Institute on Aging2021 to 2024$3,347,408August 15, 2020May 31, 2026SNYDER-CAPPIONE, JENNIFER Ereporter.nih.gov
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,343,705April 1, 2021March 31, 2026SCHRAMM, VERN L.reporter.nih.gov
The PAS Sensor Family and Human HealthNIHNational Institute of Environmental Health Sciences2021 to 2024$3,342,660September 15, 2017May 31, 2026BRADFIELD, CHRISTOPHER Areporter.nih.gov
Role of ABCG1, ABCG5 and ABCG8 in Sterol MetabolismNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,341,148February 1, 2003November 30, 2025HOBBS, HELEN HASKELLreporter.nih.gov
Periodontitis Role in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,340,009September 1, 2025August 31, 2029THUMBIGERE-MATH, VIVEKreporter.nih.gov
Liquid biopsy and radiomics for liver cancer surveillanceNIHNational Cancer Institute2023 to 2025$3,338,250September 19, 2023August 31, 2028TAOULI, BACHIRreporter.nih.gov
Immunologic correlates of functional cure of HBV with immune checkpoint blockadeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,338,136May 22, 2020April 30, 2026LAUER, GEORG MICHAELreporter.nih.gov
Why do Down Syndrome patients have high risk of Hirschsprung disease?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,330,453September 15, 2022July 31, 2027CHAKRAVARTI, ARAVINDAreporter.nih.gov
Support for Registration Enabling Phase 3 Clinical Trial for Nanotechnology-Based Treatment of Carcinoma in Situ of the Oral Cavity (Stage 0 Oral Cancer)NIHNational Cancer Institute2024 to 2025$3,329,707June 14, 2024May 31, 2027GOLDBERG, MANIJEH Nreporter.nih.gov
Smarter CRC Supplement for ACCSIS Patient NavigationNIHNational Cancer Institute2021 to 2023$3,328,541September 23, 2019August 31, 2025DAVIS, MELINDA MARIEreporter.nih.gov
Cancer Immune-Interception for Lynch SyndromeNIHNational Cancer Institute2021 to 2025$3,326,163September 21, 2021August 31, 2026VILAR SANCHEZ, EDUARDOreporter.nih.gov
Real-time MRI-guided adaptive radiotherapy of unresectable pancreatic cancerNIHNational Cancer Institute2021 to 2025$3,323,920August 13, 2021July 31, 2026OTAZO, RICARDOreporter.nih.gov
Predictive informatics monitoring in the Neonatal Intensive Care UnitNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,311,236July 10, 2014April 30, 2027FAIRCHILD, KAREN Dreporter.nih.gov
"A microbiome-dependent bile acid metabolite improves type 2 diabetes."NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,304,418January 8, 2021December 31, 2026SHEU, ERIC GARLANDreporter.nih.gov
Epigenetic study of oral HPV infection-associated oral cancer in people living with HIV in NigeriaNIHNational Cancer Institute2022 to 2025$3,301,620September 16, 2022August 31, 2027HOU, LIFANGreporter.nih.gov
The Influence Of Gut Microbiota Stability In Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,299,380March 4, 2019February 28, 2027FAITH, JEREMIAH JAMESreporter.nih.gov
A geospatial analysis of hotspots and targeted injection settings pilot intervention for HIV prevention among people who inject drugs in Baltimore, MarylandNIHNational Institute on Drug Abuse2021 to 2025$3,292,995July 1, 2020May 31, 2027LATKIN, CARL Areporter.nih.gov
Impact of HIV, oral microbiome and mycobiome on oral HPV persistenceNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,289,768September 1, 2022August 31, 2027BURK, ROBERT Dreporter.nih.gov
Fibroblast orchestration of the immune response in pancreatic cancerNIHNational Cancer Institute2022 to 2025$3,286,816September 19, 2022August 31, 2027PASCA DI MAGLIANO, MARINAreporter.nih.gov
A smartphone-enabled point-of-care HCV Ag diagnostic using catalytic nanoparticles and AI-enhanced image processingNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$3,284,055September 9, 2022June 30, 2027SHAFIEE, HADIreporter.nih.gov
Prevention of Pediatric NAFLD in Hispanic ChildrenNIHNational Institute of Nursing Research2021 to 2025$3,279,874April 5, 2021January 31, 2026WELSH, JEAN A.reporter.nih.gov
Leveraging Hyperpolarized MRI for Precision Oncology Approaches in Head and Neck CancerNIHNational Cancer Institute2022 to 2025$3,278,152September 1, 2022August 31, 2028LAI, STEPHEN Yreporter.nih.gov
Diet transformation by the microbiome and its impact on bacterial infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,277,659August 16, 2022May 31, 2027GOODMAN, ANDREW Lreporter.nih.gov
Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,276,651September 23, 2021July 31, 2027DASARATHY, SRINIVASANreporter.nih.gov
Stable therapy in Pompe disease through genome editingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,274,213August 1, 2021July 31, 2026KOEBERL, DWIGHT Dreporter.nih.gov
The Role of Secondary Bile Acids in Gastro-Esophageal NeoplasiaNIHNational Cancer Institute2022 to 2025$3,273,998September 1, 2022August 31, 2027ABRAMS, JULIANreporter.nih.gov
IL-27R signaling as a negative regulator of innate and adaptive anti-cancer immunity in hepatocellular carcinomaNIHNational Cancer Institute2022 to 2025$3,273,154August 1, 2022July 31, 2027KOLTSOVA, EKATERINAreporter.nih.gov
Functional outcomes of inflammatory bowel disease associated variantsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,272,687September 18, 2013May 31, 2028ABRAHAM, CLARAreporter.nih.gov
Genomic Epidemiology of Campylobacter to Improve Disease Control in Low and Middle Income CountriesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,270,801March 15, 2021February 28, 2027KOSEK, MARGARET Nreporter.nih.gov
Advanced Development of a Combined Shigella-ETEC VaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,267,570June 9, 2023May 31, 2028BARRY, EILEEN M.reporter.nih.gov
Longitudinal Proteomic and Metabolomic Predictors of Pancreatic Cyst Malignant Progression and Early Stage Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,264,543April 1, 2021March 31, 2027SCHMIDT, CHRISTIAN MAXIMILLIANreporter.nih.gov
Longitudinal Study of Early NAFLD Progression and the Gut Microbiome in Asian Americans, Native Hawaiians and WhitesNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,263,901September 26, 2022June 30, 2027LIM, UNHEEreporter.nih.gov
Aspiration in Acute Respiratory Failure SurvivorsNIHNational Institute of Nursing Research2021 to 2025$3,262,196August 23, 2021May 31, 2027MOSS, MARCreporter.nih.gov
Decoding mutualistic microbiota-B cell interactions in the HIV-1-infected gut: impact on immunological non-respondersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,259,183May 7, 2020April 30, 2026MEHANDRU, SAURABHreporter.nih.gov
Liver Cirrhosis Network: Longitudinal and Clinical Trial StudiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,258,965September 6, 2021July 31, 2027KHALILI, MANDANAreporter.nih.gov
Identification of enteric Juvenile Protective Factors and their role in stimulating neurogenesis in the adult and ageing Enteric Nervous SystemNIHNational Institute on Aging2021 to 2025$3,254,354January 15, 2021December 31, 2026GOFF, LOYAL ANDREWreporter.nih.gov
Lead optimization of Hepatitis B Virus ribonuclease H inhibitorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,253,243December 1, 2020November 30, 2026TAVIS, JOHN Ereporter.nih.gov
Genetic and Molecular Dissection of Wnt Pathway ActivationNIHNational Institute of General Medical Sciences2021 to 2025$3,246,880June 1, 2020July 31, 2030AHMED, YASMATHreporter.nih.gov
Implementation of telemedicine and social network driven HIV service uptake for comprehensive HIV service integration in rural syringe service programsNIHNational Institute on Drug Abuse2023 to 2025$3,234,132August 1, 2023May 31, 2028FALADE-NWULIA, OLUWASEUNreporter.nih.gov
Role of Neutrophils in the Pathogenesis of CholangiopathiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,233,421September 1, 2025August 31, 2029STRAZZABOSCO, MARIOreporter.nih.gov
Clinical Validation Center for Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2024$3,231,816May 4, 2016August 31, 2027MAITRA, ANIRBANreporter.nih.gov
Characterization and targeting of the epigenetic state underlying uveal melanoma liver metastasisNIHNational Cancer Institute2021 to 2025$3,231,041August 9, 2021July 31, 2026SMALLEY, KEIRANreporter.nih.gov
Glycomic Modulation of Gut Microbiome During HIV InfectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,228,597December 24, 2019November 30, 2025ABDEL MOHSEN, MOHAMEDreporter.nih.gov
Imaging Modulation of Immune PhenotypeNIHNational Cancer Institute2021 to 2025$3,227,270February 1, 2021January 31, 2027FERRARA, KATHERINE Wreporter.nih.gov
Defining the β-catenin/CBP-catenin/CBP axis in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,223,525December 7, 2020November 30, 2026KUKURUZINSKA, MARIA A.reporter.nih.gov
A neurocomputational assay of gastrointestinal interoception in anorexia nervosaNIHNational Institute of Mental Health2021 to 2025$3,222,559September 1, 2021June 30, 2027KHALSA, SAHIB S.reporter.nih.gov
Decoding the clinical impact of the recent evolution of metronidazole resistance on Clostridium difficile infection.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,220,673August 20, 2018January 31, 2028HURDLE, JULIAN Greporter.nih.gov
Examine Individual and Clinical Factors Affecting Liver Disease ManagementNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,219,854September 15, 2022May 31, 2027MA, GRACE X.reporter.nih.gov
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,218,917August 15, 2015June 30, 2026JENQ, ROBERTreporter.nih.gov
Addressing Chemoresistance in Pancreatic and Ovarian Cancers: Photodynamic Priming and Repurposing of Tetracyclines using Targeted Photo-Activable Multi-Inhibitor LiposomeNIHNational Cancer Institute2021 to 2025$3,218,280April 1, 2021March 31, 2027HUANG, HUANG CHIAOreporter.nih.gov
Self-Management to Optimize Survivorship Care and Outcomes in Lung and Colorectal CancerNIHNational Cancer Institute2021 to 2024$3,217,584April 2, 2020March 31, 2026SUN, VIRGINIA CHIH-YIreporter.nih.gov
Epidemiologic identification and mechanistic investigation of early life environmental risk factors for eosinophilic esophagitisNIHNational Institute of Environmental Health Sciences2021 to 2025$3,217,424April 1, 2021January 31, 2027DELLON, EVAN SAMUELreporter.nih.gov
Targeting P2 Receptors to Restore Salivary and Lacrimal Gland Function in Sjogren's SyndromeNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,216,546March 1, 2021February 28, 2027WEISMAN, GARY ANDREWreporter.nih.gov
Integrated Model for the Prevention of Anal Cancer using screen and Treat for HSIL (IMPACT)NIHNational Cancer Institute2022 to 2025$3,210,795September 15, 2022August 31, 2027NOWAK, REBECCA G.reporter.nih.gov
Active Disposable Cap for Endoscope Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile PolypsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$3,206,138August 7, 2018August 31, 2025MULVIHILL, MAUREEN L.reporter.nih.gov
Sjögren's International Collaborative Clinical Alliance Next Generation Studies (SICCA-NextGen)NIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,205,764June 1, 2020November 30, 2025SHIBOSKI, CAROLINE HELENEreporter.nih.gov
B cell clonal selection in gut-associated germinal centersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,203,164September 17, 2020August 31, 2025VICTORA, GABRIEL Dreporter.nih.gov
The impact of non-dysentery Shigella-associated diarrhea in childrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,197,662March 9, 2021February 28, 2027CHAKRABORTY, SUBHRAreporter.nih.gov
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular CarcinomaNIHNational Cancer Institute2021 to 2025$3,197,232January 18, 2021December 31, 2026ZHU, YAZHENreporter.nih.gov
Roles and regulation of tissue resident CD8 T cells during a persistent viral infectionNIHNational Institute of Allergy and Infectious Diseases2025$3,194,992July 16, 2025June 30, 2029ZUNIGA, ELINA Ireporter.nih.gov
Immunomodulation in AAV gene therapyNIHNational Institute of Allergy and Infectious Diseases2025$3,192,404August 21, 2025July 31, 2029ASOKAN, ARAVINDreporter.nih.gov
Host Responses to the Pore-Forming Toxin Listeriolysin ONIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,191,205April 1, 2021March 31, 2027SEVEAU, STEPHANIE M Mreporter.nih.gov
Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesNIHNational Cancer Institute2021 to 2025$3,190,411April 5, 2021March 31, 2027SPIEGEL, BRENNANreporter.nih.gov
Neutralizing antibody responses during natural control of acute hepatitis B with and without HIV-1 coinfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,186,484August 1, 2022July 31, 2027BAILEY, JUSTIN RICHARDreporter.nih.gov
Long-Term Islet Function and Impact after Total Pancreatectomy with Islet Autotransplant (LIFT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,185,530January 15, 2021December 31, 2026BELLIN, MELENA D.reporter.nih.gov
Collaborative Integration of HCV Molecular Virology and Mathematical ModelingNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,185,361August 1, 2010May 31, 2027UPRICHARD, SUSAN L.reporter.nih.gov
Alanyl-glutamine supplementation of standard treatment for C. difficile infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,184,912July 13, 2020June 30, 2026WARREN, CIRLE ALCANTARAreporter.nih.gov
Intestinal proteases in alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2025$3,182,397September 20, 2025August 31, 2029SCHNABL, BERND G.reporter.nih.gov
Investigation of Yop activities in M cells during murine infectionNIHNational Institute of Allergy and Infectious Diseases2025$3,178,626August 26, 2025July 31, 2029MECSAS, JOAN Creporter.nih.gov
Novel macrophage mediated signals regulate the immunoregulatory environment of the neonatal liverNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,176,680September 15, 2025September 14, 2029NIJAGAL, AMARreporter.nih.gov
Simultaneous MRI/US for real-time liver ablation guidance and confirmationNIHNational Cancer Institute2022 to 2025$3,174,892August 15, 2022July 31, 2027HOLMES, JAMES Hreporter.nih.gov
Peripherally-restricted non-addictive cannabinoids for cancer pain treatmentNIHNational Institute of Neurological Disorders and Stroke2023$3,174,343August 1, 2023July 31, 2025SPIGELMAN, IGORreporter.nih.gov
Drug eluting injectable biomaterials for next generation chemoembolizationNIHNational Cancer Institute2021 to 2025$3,173,416May 1, 2021April 30, 2027OKLU, RAHMIreporter.nih.gov
Fluorescence Lifetime Imaging/Spectroscopy System For Robotic Cancer Surgery GuidanceNIHNational Cancer Institute2021 to 2025$3,170,664September 12, 2014April 30, 2027MARCU, LAURAreporter.nih.gov
Autologous BM-MSCs and Islet Co-transplantation to Enhance Islet Survival and Function in TP-IAT PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,169,762August 24, 2021May 31, 2027WANG, HONGJUNreporter.nih.gov
CTRP and Metabolic ControlNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,168,077July 15, 2010June 30, 2028WONG, GUANG WILLIAMreporter.nih.gov
A Patient-Centric Approach to Advance Functional Precision OncologyNIHNational Cancer Institute2023 to 2025$3,167,628September 22, 2023August 31, 2028KEMP, CHRISTOPHER Jreporter.nih.gov
Development of peptide nucleic acid antibioticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,164,488February 10, 2021January 31, 2025ARYA, DEV PRIYAreporter.nih.gov
Role of Intestinal Parasites on Regulating Immune Responses to Gut AntigensNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,164,043June 22, 2022May 31, 2027EDELSON, BRIAN TODDreporter.nih.gov
Adipose tissue-colorectal tumor cross-talk: new targets for breaking the obesity-cancer linkNIHNational Cancer Institute2021 to 2025$3,159,289September 23, 2021August 31, 2026ULRICH, CORNELIA Mreporter.nih.gov
Low Cost Tethered Capsule Endoscope with High-Resolution Digital Chromoscopy for Barrett's ScreeningNIHNational Cancer Institute2021 to 2025$3,157,352July 1, 2021June 30, 2027RICHARDS-KORTUM, REBECCA R.reporter.nih.gov
Launching HBV with RNA to assess antiviral resistance and explore fundamental aspects of virus-host biologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,156,556February 10, 2020April 30, 2030RICE, CHARLES Mreporter.nih.gov
Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunityNIHNational Cancer Institute2023 to 2025$3,154,814September 19, 2023August 31, 2028BROWN, BRIAN Dreporter.nih.gov
Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and AdultsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,153,883September 24, 2018October 31, 2028HEYSELL, SCOTT Kreporter.nih.gov
Extracellular vesicle cargo and risk of NAFLD and NASH in U.S. youthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,153,279April 15, 2022February 28, 2027DISTEFANO, JOHANNA Kreporter.nih.gov
Impacting the oral HPV continuum: prevention, screening, and early detectionNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,152,738September 23, 2016June 30, 2025D'SOUZA, GYPSYAMBERreporter.nih.gov
Impact of harm reduction care in HIV clinical settings on stigma and health outcomes for PLWH who use drugsNIHNational Institute on Drug Abuse2021 to 2025$3,152,106September 30, 2021June 30, 2027HAWK, MARY ELIZABETHreporter.nih.gov
Mechanistic understanding of the lifecycle of a circulating hybrid cellNIHNational Cancer Institute2021 to 2025$3,151,928June 1, 2021May 31, 2027WONG, MELISSA H.reporter.nih.gov
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer RiskNIHNational Cancer Institute2021 to 2025$3,149,705January 15, 2021December 31, 2026FITZGIBBON, MARIAN L.reporter.nih.gov
Dendritic cell intrinsic UPR is critical for pathogen specific Th17 responsesNIHNational Institute of Allergy and Infectious Diseases2025$3,147,392September 1, 2025August 31, 2029PASARE, CHANDRASHEKHARreporter.nih.gov
Vibrio cholerae antinitrosative stress defenses and gut microbiome interactionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,145,639September 23, 2020August 31, 2025ZHU, JUNreporter.nih.gov
Microbiome, Environment, and Parkinsons disease (MEP) PESTICIDE EXPOSURES AND THE GUT MICROBIOME IN PARKINSONS DISEASENIHNational Institute of Environmental Health Sciences2021 to 2025$3,143,396August 15, 2020June 30, 2026RITZ, BEATE R.reporter.nih.gov
New Generation of Mitochondrial Uncouplers for the Treatment of Metabolic DIsordersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$3,142,274September 20, 2021June 30, 2026VU, SIMONreporter.nih.gov
Allergen Loaded Nanoparticles for Food Allergy ToleranceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,140,831September 16, 2020August 31, 2025SHEA, LONNIE Dreporter.nih.gov
Coordinating Center for the Program on the Origins of Gastroesophageal CancersNIHNational Cancer Institute2022 to 2025$3,140,717September 6, 2022August 31, 2027HUR, CHINreporter.nih.gov
Coordinated studies in monkeys and humans to assess the immunological impact of rectal Chlamydia trachomatis infection on protection against genital infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,139,154April 1, 2023March 31, 2028VOJTECH, LUCIA Nreporter.nih.gov
Engineering Native E. coli to Detect, Report, and Treat Colorectal CancerNIHNational Cancer Institute2021 to 2025$3,135,340September 21, 2021August 31, 2026ZARRINPAR, AMIRreporter.nih.gov
Shigella Conjugate Vaccine (SCV4) Development, Characterization, and Pre-clinical EvaluationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,134,727June 23, 2023May 31, 2028RYAN, EDWARD T.reporter.nih.gov
Oral microbiome and periodontal diseases in oral HPV infection among people living with HIVNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,134,374August 11, 2022July 31, 2027XIAO, CANHUAreporter.nih.gov
The Ecology of Barrett's EsophagusNIHNational Cancer Institute2025$3,130,492August 22, 2025July 31, 2029MALEY, CARLOreporter.nih.gov
Molecular mechanisms driving the coevolution of clinical isolates of phages and epidemic Vibrio choleraeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,128,015June 1, 2020May 31, 2030SEED, KIMBERLEY DIANEreporter.nih.gov
Modeling intestinal dysfunction in HIV infection with organoid technologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,127,465January 10, 2020December 31, 2025OTT, MELANIE MARIAreporter.nih.gov
Microbiota, Metabolites, and Colon NeoplasiaNIHNational Cancer Institute2021 to 2025$3,124,761May 1, 2021April 30, 2027ROSENBERG, DANIEL WILLIAMreporter.nih.gov
Structural and functional studies of colibactinNIHNational Cancer Institute2021 to 2025$3,124,458December 11, 2017February 29, 2028HERZON, SETH B.reporter.nih.gov
Intestinal microbiota-mediated rotavirus vaccine failureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,123,686September 19, 2022July 31, 2027GEWIRTZ, ANDREW Treporter.nih.gov
Innate lymphoid cell regulation of the host-microbiota interactions in cancerNIHNational Cancer Institute2022 to 2025$3,122,275September 20, 2022August 31, 2027SONNENBERG, GREGORY Freporter.nih.gov
Serial immunotherapy combination to modulate the tumor environment in patients with metastatic gastroesophageal cancerNIHNational Cancer Institute2021 to 2025$3,119,133January 1, 2021December 31, 2026YOON, HARRY Hreporter.nih.gov
SPHERE (Survivorship Plan Health Record) Implementation TrialNIHNational Cancer Institute2021 to 2025$3,117,615June 1, 2021May 31, 2027HAGGSTROM, DAVID ANDREWreporter.nih.gov
Molecular and structural characterization of broadly neutralizing anti-HCV antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,115,747February 15, 2023January 31, 2028BAILEY, JUSTIN RICHARDreporter.nih.gov
Microbiota-immune interactions that promote intestinal homeostasisNIHNational Center for Complementary & Integrative Health2021 to 2025$3,111,145June 15, 2021May 31, 2026ROUND, JUNE LOUISEreporter.nih.gov
The Role of the Microbiome and Notch Signaling in Esophageal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$3,108,327January 1, 2021December 31, 2026ABRAMS, JULIANreporter.nih.gov
Autonomous Grippers in the Gastrointestinal TractNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$3,105,853September 26, 2014June 30, 2026SELARU, FLORINreporter.nih.gov
Mechanisms of the Development and Maintenance of Salmonella Gallbladder CarriageNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,105,141June 1, 2015April 30, 2027GUNN, JOHN Sreporter.nih.gov
Epigenetics of human Hepatic Stellate Cells (HSCs) in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,103,795May 15, 2014August 31, 2027KISSELEVA, TATIANAreporter.nih.gov
Role of Lipogenic Pathways in Intestinal Remodeling after Gastric Bypass SurgeryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,103,125September 3, 2025September 2, 2029STEFATER-RICHARDS, MARGARETreporter.nih.gov
Modeling diabetes using an integrated plate systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$3,092,998September 20, 2018July 31, 2024WELLS, JAMES Mreporter.nih.gov
Leveraging Vulnerabilities Induced by STING Activation in Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,092,811February 15, 2021January 31, 2026DONAHUE, TIMOTHY Rreporter.nih.gov
Mechanisms Regulating Neurotensin Secretion and FunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,092,161February 1, 2017June 30, 2026EVERS, BERNARD MARKreporter.nih.gov
Impact of metabolic programing of T cells from the GI tract and related tissues on HIV reservoir seeding, maintenance and reactivationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,091,749September 30, 2021July 31, 2027APETREI, CRISTIANreporter.nih.gov
Characterizing the Risk of Chemotherapy Side Effects Based on Epigenetic Age and Modification by Resistance Training InterventionNIHNational Cancer Institute2021 to 2025$3,091,560September 8, 2021August 31, 2027BINDER, ALEXANDRA MARGARET LYNNreporter.nih.gov
Immune determinants of progression from Oral Epithelial Dysplasia to Oral Squamous Cell Carcinoma by precision multiplexed imagingNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,081,662June 15, 2022March 31, 2027SPITZER, MATTHEWreporter.nih.gov
Urine and serum biomarkers for early diagnosis and risk assessment of pancreatic cancerNIHNational Cancer Institute2021 to 2025$3,080,631February 3, 2021January 31, 2027LOKSHIN, ANNA E.reporter.nih.gov
TRPV1 nociceptors in oral carcinogenesis and painNIHNational Cancer Institute2021 to 2025$3,070,266March 1, 2021February 28, 2027ALBERTSON, DONNA Greporter.nih.gov
Optimizing a patient-specific regenerative larynx implant for restoration of voiceNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,070,095September 1, 2021August 31, 2027LOTT, DAVID Greporter.nih.gov
Small GTP Binding Proteins in Gastrointestinal MucosaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,070,009August 1, 1997July 31, 2027GOLDENRING, JAMES RICHARDreporter.nih.gov
Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogenNIHNational Cancer Institute2021 to 2025$3,068,738September 13, 2021August 31, 2027KHAZAIE, KHASHAYARSHAreporter.nih.gov
Mechanisms of Altered Hepatic Transport: Impact on Drug TherapyNIHNational Institute of General Medical Sciences2021 to 2025$3,067,940April 5, 2017March 31, 2027BROUWER, KIM L.R.reporter.nih.gov
Translational studies of hookworm infection in GhanaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,065,354February 22, 2022January 31, 2027CAPPELLO, MICHAELreporter.nih.gov
Anti-norovirus protease inhibitors for immunocompromised patientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,063,131August 11, 2023July 31, 2027SCHINAZI, RAYMOND FELIXreporter.nih.gov
LIVOPT -- LIVer cirrhosis - Optimizing Prediction of Patient OuTcomesNIHNational Institute on Aging2021 to 2025$3,057,044September 30, 2021May 31, 2027LADNER, DANIELA Preporter.nih.gov
RNA modifications in apolipoprotein regulation by environmental exposuresNIHNational Institute of Environmental Health Sciences2025$3,051,769September 11, 2025August 31, 2029KLINGE, CAROLYN M.reporter.nih.gov
Bile acid composition and insulin sensitivityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,050,866September 15, 2017August 31, 2027HAEUSLER, REBECCA ANNEreporter.nih.gov
Mechanism of action for the epithelial-specific ER stress sensor IRE1β in regulating intestinal homeostasis and host defenseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,050,147September 1, 1993March 31, 2026LENCER, WAYNE Ireporter.nih.gov
The Impact of HCV Treatment in HIV/HCV coinfected and HCV monoinfected Incarcerated Persons on HCV EliminationNIHNational Institute on Drug Abuse2021 to 2024$3,045,888September 30, 2020August 31, 2025IRVIN, RISHAreporter.nih.gov
Influence of maternal virome and HIV status on infant gut virome, growth and immunityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,044,222September 21, 2020August 31, 2025JASPAN, HEATHER BERYLreporter.nih.gov
Integrative single cell analyses of inflammation-derived circulating hybrid cells to identify aggressive diseaseNIHNational Cancer Institute2021 to 2025$3,044,035April 1, 2021March 31, 2027WONG, MELISSA H.reporter.nih.gov
Therapeutic Targeting Mitochondrial C1 MetabolismNIHNational Cancer Institute2021 to 2025$3,043,890January 1, 2021December 31, 2026MATHERLY, LARRY Hreporter.nih.gov
Defecation mechanisms and subtyping of constipation patients with FecobionicsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,042,512June 15, 2021May 31, 2027GREGERSEN, HANSreporter.nih.gov
GMP MANUFACTURE OF CLINICAL GRADE THERAPEUTIC VACCINE FOR THE TREATMENT OF PATIENTS WITH CHRONIC HBVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,034,670June 5, 2018March 31, 2025NAKAAR, VALERIANreporter.nih.gov
TASK D10: A PHASE 1 TRIAL TO EVALUATE A TREATMENT FOR CLOSTRIDIOIDES DIFFICILENIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,033,881January 14, 2022January 13, 2032SPITZ, ROBERTreporter.nih.gov
Lactoferrin and lysozyme to promote nutritional, clinical, and enteric recovery: A factorial placebo-controlled randomized trial among children with diarrhea and malnutritionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,033,175January 1, 2021November 30, 2025PAVLINAC, PATRICIAreporter.nih.gov
Dissecting the pathogenesis and outcomes of PSC using multi-omics by studying the exposome and genomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$3,027,125September 1, 2018July 31, 2025LAZARIDIS, KONSTANTINOS Nreporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
Study the Treg-IL-27 axis in immune regulationNIHNational Institute of Allergy and Infectious Diseases2025$3,022,197July 8, 2025June 30, 2029LU, LI-FANreporter.nih.gov
Mechanistic basis of bacteriophages for the decolonization of vancomycin resistant enterococci in the intestineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,022,123September 14, 2018July 31, 2028DUERKOP, BRECK Areporter.nih.gov
Elucidation of Pathogenic Mechanisms underlying Norovirus DiarrheaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,019,785June 1, 2021May 31, 2026KARST, STEPHANIE Mreporter.nih.gov
The Role of Type VI Secretion in Cholera PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,019,658January 18, 2019December 31, 2025PUKATZKI, STEFANreporter.nih.gov
A Randomized Trial to Test the Efficacy of a Partner Navigation Intervention for HCV Treatment among Young Adult People who Inject DrugsNIHNational Institute on Drug Abuse2022 to 2025$3,017,588June 1, 2022March 31, 2027MORRIS, MEGHAN Dreporter.nih.gov
Analysis of Chemical Structures and Therapeutic Activity of Agents for HIV, TB, and HBV (CHEMDB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,016,918September 30, 2024September 29, 2025SUMNER, LOUISEreporter.nih.gov
CARES-REACH (Colorectal Cancer Awareness, Research, Education and Screening-Rural Expansion, Access and Capacity for Health)NIHNational Cancer Institute2021 to 2024$3,016,341April 1, 2020March 31, 2026GWEDE, CLEMENT K.reporter.nih.gov
HAWAII CLINICAL RESEARCH NETWORK FOR HEALTH EQUITYNIHNational Institute on Minority Health and Health Disparities2022 to 2023$3,015,250September 24, 2022June 30, 2024SHIKUMA, CECILIA M.reporter.nih.gov
Role of the p53 P47S mutation in influencing prevalence and immune response to H. pyloriNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,013,399January 20, 2021December 31, 2026CLAIBORNE, DANIEL THOMASreporter.nih.gov
Uncovering the rules of gut microbiome strain transmissionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,013,179January 20, 2020December 31, 2028FAITH, JEREMIAH JAMESreporter.nih.gov
Dietary Fiber-Microbiome Interactions: Elucidating Mechanisms to Suppress Multi-Drug Resistant Organisms in the Human GutNIHNational Institute of Allergy and Infectious Diseases2025$3,012,181September 10, 2025August 31, 2029VENTURELLI, OPHELIAreporter.nih.gov
Multi-level Evaluation of Racial/ethnic Disparities in Liver Disease OutcomesNIHNational Cancer Institute2021 to 2025$3,010,755March 18, 2021February 28, 2027KANWAL, FASIHAreporter.nih.gov
Non-Clinical Pharmacology of CX-01NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,007,043June 1, 2014January 31, 2027VID, GALINAreporter.nih.gov
CyberGut: towards personalized human-microbiome metabolic modeling for precision health and nutritionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,006,256July 1, 2022April 30, 2027GIBBONS, SEAN MICHAELreporter.nih.gov
Generating Exogenic Organs for Transplantation without the Use of ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,005,890September 21, 2022July 31, 2027STEER, CLIFFORD JOHNreporter.nih.gov
Harnessing human brain and liver microphysiological systems for testing therapeutics for metastatic melanomaNIHNational Center for Advancing Translational Sciences2021 to 2022$3,003,024August 1, 2018July 31, 2024WIKSWO, JOHN PETERreporter.nih.gov
Mechanisms of T Cell Quiescence and ExhaustionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,001,713March 1, 2019February 28, 2029SARKAR, SUROJITreporter.nih.gov
The REASON Score: An Epigenetic And Clinicopathologic Score to Predict Risk of Poor Survival in Early Stage Oral Squamous Cell Carcinoma PatientsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,001,101August 11, 2022May 31, 2027VIET, CHI T.reporter.nih.gov
Regulating cell fate and shaping the body plan during morphogenesis and their alteration during oncogenesisNIHNational Institute of General Medical Sciences2021 to 2025$3,000,444July 1, 2016August 31, 2026PEIFER, MARK A.reporter.nih.gov
Preclinical development of capsid assembly modulators for the treatment of chronic hepatitis B virus infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000May 24, 2021April 30, 2025COBURN, GLEN ANDREWreporter.nih.gov
Regulation of mitochondrial health in mammalian livers.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,999,512September 1, 2025August 31, 2029MISHRA, PRASHANTreporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,001April 21, 2020March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon CancerNIHNational Cancer Institute2022 to 2024$2,997,017June 3, 2022February 28, 2025BROWN, JUSTIN Creporter.nih.gov
Development of TP-317 in Ulcerative ColitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,996,955September 18, 2017February 28, 2027PARKINSON, JOHNreporter.nih.gov
DIRECT TO PHASE II SBIR CONCEPT AWARD FOR NOVEL IONTOPHORETIC DRUG DELIVERY DEVICE FOR LOCAL AND EFFECTIVE TREATMENT OF ORAL CANCERNIHNational Cancer Institute2025$2,995,581September 5, 2025September 4, 2027HAM, STEPHANIEreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California Los AngelesLos Angeles, CA102$685.7 million0$0
Johns Hopkins UniversityBaltimore, MD188$291.5 million0$0
University of Michigan at Ann ArborAnn Arbor, MI256$260.9 million0$0
University of California, San DiegoLa Jolla, CA173$236 million0$0
Massachusetts General HospitalBoston, MA197$235 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA192$215.7 million0$0
University of California, San FranciscoSan Francisco, CA165$215.1 million0$0
University of PennsylvaniaPhiladelphia, PA217$203.6 million0$0
Columbia University Health SciencesNew York, NY143$201.2 million0$0
Ut Southwestern Medical CenterDallas, TX149$199.3 million0$0
Washington UniversitySaint Louis, MO192$193.5 million0$0
Yale UniversityNew Haven, CT153$190.2 million0$0
University of TX MD Anderson Can CTRHouston, TX132$182.3 million0$0
Stanford UniversityStanford, CA153$181.2 million0$0
Mayo Clinic RochesterRochester, MN116$172.7 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC142$169.9 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY109$160.4 million0$0
Vanderbilt University Medical CenterNashville, TN98$149.3 million0$0
Duke UniversityDurham, NC118$131.7 million0$0
Weill Medical Coll of Cornell UnivNew York, NY113$128.3 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY94$125.9 million0$0
University of WashingtonSeattle, WA96$125.3 million0$0
Baylor College of MedicineHouston, TX123$120.2 million0$0
Boston Children's HospitalBoston, MA73$120 million0$0
Brigham and Women's HospitalBoston, MA66$113 million0$0
University of Colorado DenverAurora, CO114$112.7 million0$0
Northwestern University at ChicagoChicago, IL67$109.9 million0$0
University of Maryland BaltimoreBaltimore, MD52$109.4 million0$0
Indiana University IndianapolisIndianapolis, IN92$103.5 million0$0
Case Western Reserve UniversityCleveland, OH62$100.3 million0$0
Emory UniversityAtlanta, GA107$95.5 million0$0
University of UtahSalt Lake City, UT94$94.2 million0$0
University of ChicagoChicago, IL78$92 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH69$90.9 million0$0
Oregon Health & Science UniversityPortland, OR61$87.3 million0$0
University of VirginiaCharlottesville, VA69$84.2 million0$0
Fred Hutchinson Cancer CenterSeattle, WA52$82.9 million0$0
University of Southern CaliforniaLos Angeles, CA70$79.7 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA60$79.1 million0$0
University of Wisconsin-MadisonMadison, WI71$78.8 million0$0
University of FloridaGainesville, FL94$75.4 million0$0
University of ArizonaTucson, AZ62$74.8 million0$0
Albert Einstein College of MedicineBronx, NY44$73.6 million0$0
Ohio State UniversityColumbus, OH75$73.2 million0$0
Medical University of South CarolinaCharleston, SC63$71.8 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA36$70.6 million0$0
New York University School of MedicineNew York, NY63$68.7 million0$0
University of MinnesotaMinneapolis, MN64$65.5 million0$0
University of Alabama at BirminghamBirmingham, AL71$65 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH53$64.4 million0$0
University of LouisvilleLouisville, KY50$64.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA59$62.6 million0$0
University of California at DavisDavis, CA70$61.8 million0$0
University of Nebraska Medical CenterOmaha, NE60$61.3 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX50$59.8 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL24$59.6 million0$0
Dana-Farber Cancer InstBoston, MA49$51.9 million0$0
University of Illinois at ChicagoChicago, IL54$51.1 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK47$50.6 million0$0
University of IowaIowa City, IA43$49.2 million0$0
University of KentuckyLexington, KY47$48.9 million0$0
Medical College of WisconsinMilwaukee, WI43$46.7 million0$0
Beth Israel Deaconess Medical CenterBoston, MA38$45.5 million0$0
Seattle Children's HospitalSeattle, WA23$45.1 million0$0
Beckman Research Institute/city of HopeDuarte, CA32$45 million0$0
Wake Forest University Health SciencesWinston-Salem, NC36$42.9 million0$0
University of Texas HLTH Science CenterSan Antonio, TX33$42.7 million0$0
University of Miami School of MedicineCoral Gables, FL41$42.4 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA29$41.8 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ47$41 million0$0
University of Kansas Medical CenterKansas City, KS41$41 million0$0
Saint Louis UniversitySaint Louis, MO19$39.9 million0$0
New York UniversityNew York, NY23$38.4 million0$0
University of Missouri-ColumbiaColumbia, MO29$37.3 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY15$36.7 million0$0
Virginia Commonwealth UniversityRichmond, VA41$36.3 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL34$35.2 million0$0
Boston University Medical CampusBoston, MA25$34.3 million0$0
Rockefeller UniversityNew York, NY27$34.2 million0$0
Michigan State UniversityEast Lansing, MI32$34.2 million0$0
University of California-IrvineIrvine, CA33$33.9 million0$0
Vanderbilt UniversityNashville, TN41$32.7 million0$0
Tulane University of LouisianaNew Orleans, LA33$31.4 million0$0
Salk Institute for Biological StudiesLa Jolla, CA13$30.7 million0$0
Thomas Jefferson UniversityPhiladelphia, PA31$30.4 million0$0
North Carolina State UniversityRaleigh, NC24$30.4 million0$0
Lurie Children's Hospital of ChicagoChicago, IL17$30.3 million0$0
University of RochesterRochester, NY32$29.9 million0$0
Scripps Research Institute, theLa Jolla, CA23$29.7 million0$0
Wayne State UniversityDetroit, MI26$29.6 million0$0
Research Inst Nationwide Children's HospColumbus, OH25$28.6 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA22$27.7 million0$0
Kaiser Foundation Research InstituteOakland, CA15$26.1 million0$0
University of Texas Med BR GalvestonGalveston, TX27$26 million0$0
University of HawaiiHonolulu, HI14$25.7 million0$0
Oklahoma Medical Research FoundationOklahoma City, OK11$24.5 million0$0
Mayo Clinic ArizonaScottsdale, AZ18$24.3 million0$0
University of California-BerkeleyBerkeley, CA20$23.6 million0$0
SUNY at BuffaloAmherst, NY23$23.2 million0$0
Georgetown UniversityWashington, DC33$22.9 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20254,231$2,378,928,3970$0
20244,491$2,199,454,1530$0
20234,491$2,251,667,0910$0
20224,458$2,201,388,9390$0
20214,433$2,143,559,3930$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 81 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 17 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 13 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 9 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 8 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 7 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 4 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIHDecember 3, 2026Not listedNotice number printed on 1 award here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIHJanuary 7, 2028Not listedNotice number printed on 1 award here
Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)RFA-DK-27-125NIH93.847November 6, 2026Not listedSame assistance listing 93.847 as 2,546 awards here
Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)RFA-DK-27-112NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 2,546 awards here
Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)RFA-DK-27-139NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 2,546 awards here
Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)RFA-DK-27-122NIH93.847November 17, 2026Not listedSame assistance listing 93.847 as 2,546 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.847December 4, 2026Not listedSame assistance listing 93.847 as 2,546 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.847January 5, 2027Not listedSame assistance listing 93.847 as 2,546 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.847January 7, 2027Not listedSame assistance listing 93.847 as 2,546 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.847January 15, 2027$350,000Same assistance listing 93.847 as 2,546 awards here
Diabetes Research Centers (P30 Clinical Trial Optional)RFA-DK-26-310NIH93.847January 27, 2027$1 millionSame assistance listing 93.847 as 2,546 awards here
NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)RFA-DK-28-114NIH93.847January 28, 2027Not listedSame assistance listing 93.847 as 2,546 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.