Skip to the page

Data / Research funding / Dementia

Dementia: 8,438 NIH awards ($15.5B) to 792 organizations

8,438 NIH awards ($15.5B) in the NIH spending category Dementia, to 792 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Topic
NIH spending category

Awards

The 500 largest of 8,438 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Health and Retirement Study: Yrs 35-40NIHNational Institute on Aging2021 to 2025$142,220,153September 25, 1990December 31, 2029WEIR, DAVID R.reporter.nih.gov
Alzheimer's Clinical Trials Consortium (ACTC)NIHNational Institute on Aging2021 to 2025$119,771,576December 2, 2017August 31, 2028AISEN, PAUL S.reporter.nih.gov
Alzheimer's Disease Neuroimaging Initiative (ADNI4)NIHNational Institute on Aging2022 to 2025$95,332,786September 30, 2004July 31, 2028WEINER, MICHAEL Wreporter.nih.gov
Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)NIHNational Institute on Aging2021 to 2025$82,684,947September 30, 2020August 31, 2026HANDEN, BENJAMIN Lreporter.nih.gov
DIAN-TU Primary Prevention TrialNIHNational Institute on Aging2021 to 2025$79,373,454September 15, 2018May 31, 2026MCDADE, ERIC MARTINreporter.nih.gov
NIA AD/ADRD Health Care Systems Research CollaboratoryNIHNational Institute on Aging2021 to 2025$69,169,841September 1, 2019August 31, 2030MOR, VINCENTreporter.nih.gov
Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD ProjectNIHNational Institute on Aging2022 to 2025$66,521,567September 1, 2022August 31, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)NIHNational Institute on Aging2021 to 2025$65,403,220July 15, 2002May 31, 2027FOROUD, TATIANA M.reporter.nih.gov
The National Health and Aging Trends Study and National Study of CaregivingNIHNational Institute on Aging2021 to 2025$65,386,641September 30, 2008March 31, 2029SCHRACK, JENNIFER ANNreporter.nih.gov
The Alzheimer's Disease Tau Platform Clinical TrialNIHNational Institute on Aging2023 to 2024$60,700,604September 21, 2023August 31, 2028BOXER, ADAM L.reporter.nih.gov
ADRC Consortium for Clarity in ADRD Research Through ImagingNIHNational Institute on Aging2023 to 2024$60,357,563September 15, 2023August 31, 2028JOHNSON, STERLING Creporter.nih.gov
The Long Life Family StudyNIHNational Institute on Aging2021 to 2025$60,108,132August 15, 2019June 30, 2030PROVINCE, MICHAEL A.reporter.nih.gov
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)NIHNational Institute on Aging2021 to 2025$56,766,232September 15, 2019August 31, 2030BOEVE, BRADLEY Freporter.nih.gov
DIAN-TU: Tau Next Generation Prevention TrialNIHNational Institute on Aging2021 to 2025$49,839,335September 15, 2020May 31, 2027BATEMAN, RANDALL Jreporter.nih.gov
A multimodal brain cell atlas and community resource of Alzheimer's disease and comorbid dementias.NIHNational Institute on Aging2021 to 2025$48,445,852March 1, 2020August 31, 2030LEIN, EDreporter.nih.gov
National Alzheimer's Coordinating CenterNIHNational Institute on Aging2021 to 2025$45,845,722June 15, 2021May 31, 2027STEPHENS, KARI Areporter.nih.gov
IU/JAX/PITT MODEL-AD CenterNIHNational Institute on Aging2021 to 2025$45,129,948September 30, 2016August 31, 2027LAMB, BRUCE Treporter.nih.gov
Longitudinal multicenter head-to-head harmonization of tau PET tracersNIHNational Institute on Aging2021 to 2025$41,111,092September 1, 2021May 31, 2027PASCOAL, THARICKreporter.nih.gov
UC Irvine MODEL-ADNIHNational Institute on Aging2021 to 2025$40,119,354September 15, 2017August 31, 2027LAFERLA, FRANK Mreporter.nih.gov
Randomized Double Blind, Placebo Controlled, Parallel Group Trial to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease over 18 MonthsNIHNational Institute on Aging2021 to 2025$39,702,286June 1, 2020May 31, 2027CAGGIANO, ANTHONY Oreporter.nih.gov
Wisconsin longitudinal study: Initial lifetime's impact on Alzheimer's disease and related disorders (WLS-ILIAD)NIHNational Institute on Aging2021 to 2025$39,317,019September 15, 2018February 29, 2028ASTHANA, SANJAYreporter.nih.gov
Study of Muscle, Mobility and Aging: SOMMA2NIHNational Institute on Aging2021 to 2025$38,028,895June 15, 2018June 30, 2029CUMMINGS, STEVEN RONreporter.nih.gov
Alzheimer's Disease Sequencing Project Phenotype Harmonization ConsortiumNIHNational Institute on Aging2021 to 2025$37,497,984September 30, 2021August 31, 2026HOHMAN, TIMOTHY Jreporter.nih.gov
Cognitive training to reduce incidence of cognitive impairment in older adultsNIHNational Institute on Aging2021 to 2024$37,326,564February 1, 2021January 31, 2027O'BRIEN, JENNIFER LEEreporter.nih.gov
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyNIHNational Institute on Aging2021 to 2025$36,277,689August 1, 2020April 30, 2027O'BRYANT, SID Ereporter.nih.gov
Randomized, Double-Blind, Placebo-Controlled, Phase 3 StudyNIHNational Institute on Aging2021 to 2024$36,190,244August 15, 2020May 31, 2025ABUSHAKRA, SUSANreporter.nih.gov
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)NIHNational Institute on Aging2022 to 2025$35,910,792July 1, 2022June 30, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
The Neighborhoods Study: Contextual Disadvantage and Alzheimer’s Disease and Related Dementias (ADRD)NIHNational Institute on Aging2021 to 2025$35,388,433March 1, 2021May 31, 2026KIND, AMY J.reporter.nih.gov
The Emory Healthy Brain Study: Discovering Predictive Biomarkers for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$35,158,235February 15, 2021January 31, 2027LAH, JAMES Jreporter.nih.gov
Combination anti-amyloid therapy for preclinical Alzheimer's diseaseNIHNational Institute on Aging2021 to 2024$34,903,050September 30, 2018May 31, 2025AISEN, PAUL S.reporter.nih.gov
A Next Generation Data Infrastructure to Understand Disparities across the Life CourseNIHNational Institute on Aging2023 to 2025$34,372,705August 15, 2023July 31, 2028KAPTEYN, ARIEreporter.nih.gov
Education and Cognitive Functioning in Later Life: The Nation’s High School Class of 1972NIHNational Institute on Aging2024 to 2025$32,776,590September 30, 2022July 31, 2027MULLER, CHANDRA Lreporter.nih.gov
Early Onset AD Consortium - the LEAD Study (LEADS)NIHNational Institute on Aging2021 to 2023$31,594,379September 30, 2018May 31, 2025APOSTOLOVA, LIANA Greporter.nih.gov
IUSM TREAT-AD CenterNIHNational Institute on Aging2021 to 2025$31,208,587September 30, 2019November 30, 2029PALKOWITZ, ALAN D.reporter.nih.gov
Phase II randomized controlled trial of benfotiamine in early Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$30,295,384July 15, 2022June 30, 2028GIBSON, GARY Ereporter.nih.gov
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP)NIHNational Institute on Aging2024 to 2025$30,281,212August 15, 2024July 31, 2029BOXER, ADAM L.reporter.nih.gov
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Dementia with Lewy BodiesNIHNational Institute on Aging2021 to 2023$29,498,064May 15, 2021April 30, 2025CAGGIANO, ANTHONY Oreporter.nih.gov
Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical TrialNIHNational Institute on Aging2021 to 2025$28,784,116August 15, 2019April 30, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
Generation, Characterization, and Validation of Marmoset Models of Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$28,395,368September 1, 2022August 31, 2027SILVA, AFONSO Creporter.nih.gov
Bridge Funding for Dominantly Inherited Alzheimer NetworkNIHNational Institute on Aging2021 to 2025$27,724,157September 15, 2008June 30, 2026BATEMAN, RANDALL Jreporter.nih.gov
The INCLUDE Data Coordinating CenterNIHNational Heart, Lung, and Blood Institute2021 to 2025$27,560,616September 26, 2020August 31, 2030RESNICK, ADAM CAINreporter.nih.gov
API A4 Alzheimer's Prevention TrialNIHNational Institute on Aging2021 to 2025$26,251,396September 1, 2018November 30, 2025REIMAN, ERIC MICHAELreporter.nih.gov
ASPirin in Reducing Events in the Elderly - eXTensionNIHNational Institute on Aging2021 to 2023$24,851,437July 15, 2019April 30, 2026MURRAY, ANNE Mreporter.nih.gov
US POINTER Neuroimaging Ancillary StudyNIHNational Institute on Aging2021 to 2025$24,762,483August 1, 2019March 31, 2027LANDAU, SUSAN Mreporter.nih.gov
Precision Monitoring and Assessment in the Framingham Study: Cognitive, MRI, Genetic and Biomarker Precursors of AD & DementiaNIHNational Institute on Aging2021 to 2024$24,586,693September 15, 2020May 31, 2026FARRER, LINDSAY A.reporter.nih.gov
Center without Walls for Imaging Proteinopathies with PETNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$24,457,384September 24, 2019July 31, 2029MACH, ROBERT Hreporter.nih.gov
Asian Cohort for Alzheimer's Disease (ACAD)NIHNational Institute on Aging2023 to 2025$24,263,451July 1, 2023June 30, 2028WANG, LI-SANreporter.nih.gov
Metformin in Alzheimer's dementia Prevention (MAP)NIHNational Institute on Aging2021 to 2025$24,224,790August 15, 2019April 30, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
Integrating Information about Aging Surveys: Novel Integration of Contextual Data to Study Late-Life Cognition and Alzheimer’s Disease and Related Dementia and Dementia CareNIHNational Institute on Aging2021 to 2025$23,672,206May 1, 2007March 31, 2027LEE, JINKOOKreporter.nih.gov
Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Open-Label Extension StudyNIHNational Institute on Aging2021 to 2024$23,438,396May 15, 2019December 31, 2025SPERLING, REISA A.reporter.nih.gov
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$23,431,388August 15, 2021July 31, 2027MUCKE, LENNARTreporter.nih.gov
Interactions of SARS-CoV-2 infection and genetic variation on the risk of cognitive decline and Alzheimer’s disease in Ancestral and Admixed PopulationsNIHNational Institute on Aging2023 to 2025$23,106,653August 15, 2023July 31, 2028DE ERAUSQUIN, GABRIEL ALEJANDROreporter.nih.gov
Resilience/Resistance to Alzheimer's Disease in Centenarians and Offspring (RADCO)NIHNational Institute on Aging2021 to 2025$23,099,141September 30, 2021August 31, 2027PERLS, THOMAS Treporter.nih.gov
THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITENIHNational Institute on Aging2021 to 2025$21,982,300April 1, 2012April 30, 2027WANG, LI-SANreporter.nih.gov
Wisconsin Registry for Alzheimer's PreventionNIHNational Institute on Aging2023 to 2025$21,491,270June 1, 2023February 29, 2028JOHNSON, STERLING Creporter.nih.gov
BRAIN CONNECTS: A Center for High-throughput Integrative Mouse ConnectomicsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$21,489,807September 8, 2023August 31, 2028LICHTMAN, JEFF Wreporter.nih.gov
APOE in the Predisposition to, Protection from and Prevention of Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$21,355,638September 30, 2020March 31, 2027REIMAN, ERIC MICHAELreporter.nih.gov
Unraveling the earliest phases of vascular cognitive impairment and dementia using CADASIL--a monogenic form of small vessel cerebrovascular diseaseNIHNational Institute on Aging2021 to 2025$21,188,740September 30, 2021August 31, 2027PAULSEN, JANE Sreporter.nih.gov
Penn Artificial Intelligence and Technology Collaboratory for Healthy AgingNIHNational Institute on Aging2021 to 2025$21,174,898September 30, 2021May 31, 2027DEMIRIS, GEORGEreporter.nih.gov
A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Mild-to-Moderate Dementia with Lewy Bodies (DLB)NIHNational Institute on Aging2023 to 2025$21,072,036February 1, 2023January 31, 2026ALAM, JOHNreporter.nih.gov
Delaware Clinical and Translational Research ACCEL ProgramNIHNational Institute of General Medical Sciences2021 to 2025$21,011,968September 25, 2013June 30, 2028HICKS, GREGORY Ereporter.nih.gov
The Origins of Alzheimer Disease in African AmericansNIHNational Institute on Aging2022 to 2025$20,889,453September 15, 2022June 30, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
Alzheimer's Gut Microbiome ProjectNIHNational Institute on Aging2021 to 2023$20,743,566September 15, 2019August 31, 2025KADDURAH-DAOUK, RIMA Freporter.nih.gov
Frontotemporal Dementia: Genes, Images, and EmotionsNIHNational Institute on Aging2021 to 2025$20,694,825September 1, 2002April 30, 2028GORNO TEMPINI, MARIA LUISAreporter.nih.gov
Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-OldNIHNational Institute on Aging2022 to 2025$20,680,832September 15, 2017June 30, 2027WHITMER, RACHEL Areporter.nih.gov
Additional Sequencing for the Alzheimer Disease Sequencing Project (ADSP) the Follow-Up Study (FUS), The Diverse Population InitiativeNIHNational Institute on Aging2022 to 2024$20,575,729September 1, 2022August 31, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
Alzheimer's Prevention Initiative ADAD Colombia Trial ProgramNIHNational Institute on Aging2024 to 2025$20,406,409September 1, 2024August 31, 2029ALEXANDER, ROBERT Creporter.nih.gov
Einstein Aging StudyNIHNational Institute on Aging2021 to 2024$20,102,748September 29, 1982March 31, 2028DERBY, CAROL A.reporter.nih.gov
Massachusetts Alzheimer's Disease Research Center (MADRC)NIHNational Institute on Aging2021 to 2025$19,915,545May 15, 2019March 31, 2029GOMEZ-ISLA, TERESAreporter.nih.gov
National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)NIHNational Institute on Aging2021 to 2025$19,881,397August 1, 2017April 30, 2027MAYEUX, RICHARD Preporter.nih.gov
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30NIHNational Institute on Aging2021 to 2025$18,959,959May 1, 2019March 31, 2029BREWER, JAMES Breporter.nih.gov
Health, Aging and Dementia in South Africa: A Longitudinal Study (HAALSI)NIHNational Institute on Aging2021 to 2025$18,706,904September 15, 2013May 31, 2028BERKMAN, LISA Freporter.nih.gov
Mayo Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$18,486,241July 1, 2019April 30, 2029BOEVE, BRADLEY Freporter.nih.gov
Lifecourse health, cerebral pathology and differences in dementia risk (KHANDLE Study)NIHNational Institute on Aging2021 to 2025$18,022,067June 1, 2016February 28, 2027WHITMER, RACHEL Areporter.nih.gov
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$17,997,906May 15, 2022January 31, 2028GONZALEZ, HECTOR Mreporter.nih.gov
Mount Sinai Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,735,870May 1, 2020March 31, 2030SANO, MARYreporter.nih.gov
Aging eyes and aging brains in studying alzheimer's disease: Modern ophthalmic data collection in the adult changes in thought (ACT) studyNIHNational Institute on Aging2021 to 2024$17,711,217September 1, 2019August 31, 2029LEE, CECILIA SUNGMINreporter.nih.gov
Additional Sequencing for the Alzheimer's Disease Sequencing Project (ADSP)NIHNational Institute on Aging2021 to 2024$17,661,924July 1, 2020June 30, 2026VANCE, JEFFERY MARVINreporter.nih.gov
Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,255,961June 15, 2020April 30, 2030SMALL, SCOTT Areporter.nih.gov
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)NIHNational Institute on Aging2021 to 2025$17,112,209August 15, 2018May 31, 2029HUGHES, TIMOTHY M.reporter.nih.gov
Offspring Study of Mechanisms for Racial Disparities in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$17,095,138September 1, 2016May 31, 2027MANLY, JENNIFER JAIEreporter.nih.gov
NORTHWESTERN Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,093,229August 15, 2021June 30, 2026VASSAR, ROBERT Jreporter.nih.gov
Strategies for targeting astrocyte reactivity in Alzheimer's disease and related dementiasNIHNational Institute on Aging2022 to 2025$17,073,728September 1, 2022June 30, 2027NORRIS, CHRISTOPHER MARKreporter.nih.gov
Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD)NIHNational Institute on Aging2023 to 2025$17,039,516August 15, 2023April 30, 2028HARRIS, KATHLEEN MULLANreporter.nih.gov
Biomarkers of Cognitive Decline Among Normal Individuals: The Biocard CohortNIHNational Institute on Aging2021 to 2025$16,952,609July 1, 2009May 31, 2027ALBERT, MARILYN S.reporter.nih.gov
Goizueta Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$16,684,611July 15, 2020April 30, 2030LEVEY, ALLAN Ireporter.nih.gov
Diabetes and brain amyloid in middle aged HispanicsNIHNational Institute on Aging2021 to 2025$16,383,484September 1, 2015May 31, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
Cognition & Hippocampal/Cortical Systems in AgingNIHNational Institute on Aging2021 to 2025$16,383,227September 1, 1997March 31, 2027KNIERIM, JAMES Jreporter.nih.gov
National Social Life, Health, and Aging Project: Round 5NIHNational Institute on Aging2021 to 2025$16,330,170September 15, 2014April 30, 2029WAITE, LINDA Jreporter.nih.gov
University of Kansas Alzheimer's Disease Research Center (KU ADRC)NIHNational Institute on Aging2021 to 2025$16,309,323August 15, 2021June 30, 2026SWERDLOW, RUSSELL H.reporter.nih.gov
Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsNIHNational Institute of Neurological Disorders and Stroke2024$16,244,011September 24, 2001August 31, 2026JUDD, SUZANNE Ereporter.nih.gov
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectNIHNational Institute on Aging2021 to 2025$16,156,406January 15, 2021December 31, 2026HUMMER, ROBERT Areporter.nih.gov
The Alzheimer's Disease Research Center at the University of California, IrvineNIHNational Institute on Aging2021 to 2025$16,032,156June 15, 2020March 31, 2030LAFERLA, FRANK Mreporter.nih.gov
Alzheimer's Disease Genetics ConsortiumNIHNational Institute on Aging2021 to 2024$15,948,152April 1, 2009March 31, 2026SCHELLENBERG, GERARD DAVIDreporter.nih.gov
Arizona Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$15,728,435September 5, 2021June 30, 2027LANGBAUM, JESSICA BROOKEreporter.nih.gov
Educational and Early Life Predictors of Mild Cognitive Impairment: New Evidence about Mediators and Moderators from High School & BeyondNIHNational Institute on Aging2021 to 2022$15,706,591May 15, 2019February 29, 2024WARREN, JOHN ROBERTreporter.nih.gov
ARIC Neurocognitive Study (ARIC-NCS) RenewalNIHNational Heart, Lung, and Blood Institute2021 to 2022$15,682,941July 7, 2010March 31, 2024CORESH, JOSEFreporter.nih.gov
Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementiasNIHNational Institute on Aging2021 to 2025$15,514,157September 30, 2021May 31, 2027ELLERBY, LISA Mreporter.nih.gov
Center for Pacific Innovations, Knowledge, and Opportunities (PIKO)NIHNational Institute of General Medical Sciences2021 to 2025$15,507,862September 1, 2021July 31, 2027KAHOLOKULA, JOSEPH KEAWE'AIMOKUreporter.nih.gov
The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4)NIHNational Institute on Aging2021 to 2024$15,274,483September 1, 2015March 31, 2026PANIZZON, MATTHEW Sreporter.nih.gov
NIH NATIONAL BRAIN AND TISSUE REPOSITORYNIHNational Institute on Drug Abuse2021 to 2025$14,799,056May 1, 2025October 31, 2025reporter.nih.gov
Johns Hopkins University Trial Innovation CenterNIHNational Center for Advancing Translational Sciences2023 to 2025$14,762,337July 5, 2023April 30, 2028HANLEY, DANIEL Freporter.nih.gov
English Longitudinal Study of Ageing - Renewal 2024NIHNational Institute on Aging2021 to 2025$14,720,227September 30, 2000May 31, 2029STEPTOE, ANDREWreporter.nih.gov
Alzheimer's Disease Research CentersNIHNational Institute on Aging2021 to 2025$14,719,450September 1, 2020March 31, 2030CHUI, HELENA CHANGreporter.nih.gov
Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategiesNIHNational Institute on Aging2022 to 2025$14,689,794September 15, 2019December 31, 2026PERLS, THOMAS Treporter.nih.gov
Causes and Consequences of Healthcare Inefficiency in Alzheimer’s Disease and Related DementiasNIHNational Institute on Aging2021 to 2025$14,684,279August 1, 2001July 31, 2028BARNATO, AMBER Ereporter.nih.gov
Alzheimer's Disease Research Center - Administrative Supplement 2025NIHNational Institute on Aging2021 to 2025$14,671,380May 1, 2020April 30, 2026WISNIEWSKI, THOMAS Mreporter.nih.gov
Global Alzheimer's Platform Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$14,626,193May 1, 2017April 30, 2024AISEN, PAUL S.reporter.nih.gov
Advancing cross-disease comparisons through FAIR data practices to uncover shared molecular mechanisms between Alzheimer's disease and autoimmune disordersNIHNational Institute on Aging2021 to 2025$14,514,376September 1, 2025April 30, 2027HEATH, LAURA MICHELLEreporter.nih.gov
Integrative Pathways to Cognitive, Affective, and Brain HealthNIHNational Institute on Aging2022 to 2025$14,488,542September 30, 2022August 31, 2028RYFF, CAROL D.reporter.nih.gov
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksNIHNational Institute on Aging2021 to 2024$14,414,001September 15, 2020August 31, 2025THOMPSON, PAUL Mreporter.nih.gov
Long-term effects of hearing intervention on brain health in the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized studyNIHNational Institute on Aging2022 to 2025$14,339,100August 15, 2022July 31, 2028DEAL, JENNIFER ANNEreporter.nih.gov
Mild Cognitive Impairment: A Prospective Community StudyNIHNational Institute on Aging2021 to 2025$14,337,476September 1, 2005April 30, 2026GANGULI, MARYreporter.nih.gov
National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4NIHNational Institute on Aging2021 to 2025$14,285,263September 1, 2013February 28, 2027WAITE, LINDA Jreporter.nih.gov
Study of Healthy Aging in African AmericansNIHNational Institute on Aging2023 to 2025$14,240,222January 1, 2017May 31, 2028WHITMER, RACHEL Areporter.nih.gov
The Mobile Toolbox for Monitoring Cognitive and Behavioral Function (MTB2)NIHNational Institute on Aging2021 to 2024$14,206,304September 15, 2018May 31, 2029GERSHON, RICHARDreporter.nih.gov
Education and Cognitive Functioning in Later Life: The Nation’s High School Class of 1972NIHNational Institute on Aging2022 to 2023$14,187,625September 30, 2022July 31, 2027MULLER, CHANDRA Lreporter.nih.gov
MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$14,117,524April 1, 2019September 30, 2026GUSTAFSON, DEBORAH R.reporter.nih.gov
Vanderbilt Memory & Aging ProjectNIHNational Institute on Aging2021 to 2025$14,019,775March 15, 2011March 31, 2027JEFFERSON, ANGELA L.reporter.nih.gov
Multicultural Community Dementia ScreeningNIHNational Institute on Aging2021 to 2025$13,797,203May 1, 2021January 31, 2027GALVIN, JAMES Ereporter.nih.gov
Wyoming Sensory Biology COBRENIHNational Institute of General Medical Sciences2021 to 2025$13,747,906September 1, 2017July 31, 2027SUN, QIAN-QUANreporter.nih.gov
Admin. Supp.: Correction of Neurological Disease via Allele Specific Excision of Pathogenic RepeatsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$13,703,967May 15, 2023April 30, 2028DOUDNA, JENNIFER Areporter.nih.gov
A Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Phase II Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Mild to Moderate Alzheimerʼs DiseaseNIHNational Institute on Aging2021$13,634,548September 15, 2018May 31, 2024CAGGIANO, ANTHONY Oreporter.nih.gov
Lysosome Regulation and Signaling in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$13,495,371June 1, 2021February 28, 2027ZHENG, HUIreporter.nih.gov
1Florida Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$13,348,245June 15, 2020April 30, 2027SMITH, GLENN E.reporter.nih.gov
Epidemiological and Genetic Investigations of Blood-Based Biomarkers for Alzheimer's Disease in the Multiethnic, Washington Heights, Inwood, Columbia Aging Project (WHICAP)NIHNational Institute on Aging2021 to 2025$13,310,071June 1, 2021March 31, 2027MAYEUX, RICHARD Preporter.nih.gov
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028NIHNational Heart, Lung, and Blood Institute2024 to 2025$13,305,831July 7, 2010March 31, 2029CORESH, JOSEFreporter.nih.gov
MIND DIET AND DEMENTIA PREVENTION IN ISCHEMIC STROKE PATIENTSNIHNational Institute on Aging2021 to 2025$13,186,351September 1, 2020May 31, 2027AGGARWAL, NEELUM T.reporter.nih.gov
Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Surveys in India (LASI)NIHNational Institute on Aging2021 to 2025$13,167,007September 15, 2015April 30, 2026LEE, JINKOOKreporter.nih.gov
Plasma brain-derived tau: a novel Alzheimer’s disease-type neurodegeneration biomarker with potential to complete the AT(N) scheme in bloodNIHNational Institute on Aging2023 to 2025$12,972,426September 1, 2023May 31, 2028KARIKARI, THOMAS Kreporter.nih.gov
The A3 Study: Ante-Amyloid Prevention of Alzheimer's diseaseNIHNational Institute on Aging2021 to 2023$12,937,549August 15, 2016April 30, 2024SPERLING, REISA A.reporter.nih.gov
Testing Hypothesized Pathways Linking Infection, Physical Activity, Apoe Genotype, And Biological Sex To Low Dementia Prevalence And Reduced Brain Atrophy In Two Native American PopulationsNIHNational Institute on Aging2022 to 2025$12,690,286April 15, 2017April 30, 2027KAPLAN, HILLARD Sreporter.nih.gov
Medicare at a CrossroadsNIHNational Institute on Aging2021 to 2025$12,593,170August 15, 2009April 30, 2030LANDON, BRUCE E.reporter.nih.gov
A Randomized, Double-Blind, Placebo-Controlled Study of LHP588 in Subjects with P. gingivalis-Positive Alzheimer's DiseaseNIHNational Institute on Aging2025$12,591,952August 15, 2025July 31, 2029DETKE, MICHAEL J.reporter.nih.gov
Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial of T3D-959 in Mild to Moderate Alzheimer's Disease SubjectsNIHNational Institute on Aging2021 to 2022$12,573,346May 1, 2019February 28, 2023DIDSBURY, JOHNreporter.nih.gov
Investigating regional and cellular vulnerabilities to tau pathology in young-onset Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$12,536,106February 15, 2022November 30, 2026MURRAY, MELISSA ERINreporter.nih.gov
Center for Addiction and Disease Risk ExacerbationNIHNational Institute of General Medical Sciences2021 to 2025$12,487,946August 1, 2019July 31, 2029MONTI, PETER M.reporter.nih.gov
Impacts of receiving Alzheimer's disease genetic risk information among Latinos in northern ManhattanNIHNational Institute on Aging2021 to 2024$12,295,034February 15, 2020November 30, 2025OTTMAN, RUTHreporter.nih.gov
Exploring Cognitive Aging Using Reference Ability Neural NetworksNIHNational Institute on Aging2021 to 2025$12,167,937September 1, 2011June 30, 2027STERN, YAAKOVreporter.nih.gov
Center for Research and Education on Aging and Technology Enhancement - CREATENIHNational Institute on Aging2022 to 2025$12,069,399June 15, 2022May 31, 2027CZAJA, SARA Jreporter.nih.gov
Alzheimers Disease Patient Registry (Administrative Supplement)NIHNational Institute on Aging2021 to 2023$11,991,901September 30, 1986June 30, 2026PETERSEN, RONALD Creporter.nih.gov
A Placebo-Controlled Effectiveness in INPH Shunting (PENS) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$11,962,900September 30, 2021July 31, 2027LUCIANO, MARK GREGORYreporter.nih.gov
DIAN-TU: Next Generation Prevention TrialNIHNational Institute on Aging2022 to 2023$11,960,034September 1, 2017May 31, 2024BATEMAN, RANDALL Jreporter.nih.gov
Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems.NIHNational Institute on Aging2021 to 2025$11,898,685September 15, 2007May 31, 2029TRIVEDI, AMAL N.reporter.nih.gov
I3C DECADE: Developmental Epidemiology of Childhood Cardiovascular Exposures and Alzheimer’s DementiaNIHNational Institute on Aging2022 to 2025$11,889,015July 1, 2022April 30, 2028MACLEHOSE, RICHARD Freporter.nih.gov
REVERSE-Long COVID: A Multicenter Randomized, Placebo-Controlled Clinical Trial of Immunomodulation (with Baricitinib) for Long COVID Related ADRDNIHNational Institute on Aging2024 to 2025$11,773,020January 1, 2024December 31, 2028ELY, E WESLEYreporter.nih.gov
Cross Sectional and Longitudinal Racial Disparity in Molecular Biomarkers of Alzheimer DiseaseNIHNational Institute on Aging2021 to 2024$11,652,217June 1, 2020March 31, 2026XIONG, CHENGJIEreporter.nih.gov
Kynurenine accumulation drives loss of muscle and bone function with agingNIHNational Institute on Aging2021 to 2025$11,563,609May 1, 2011May 31, 2027ISALES, CARLOS M.reporter.nih.gov
Estrogens, Cardiometabolic Health, and Female Cognitive AgingNIHNational Institute on Aging2022 to 2025$11,521,268March 1, 2022February 28, 2027DANIEL, JILL Mreporter.nih.gov
Mapping Cellular Resolution Connectopathies in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$11,497,463May 15, 2022April 30, 2027DONG, HONG-WEIreporter.nih.gov
Sleep in Neurocognitive Aging and Alzheimers Research (SANAR)NIHNational Institute on Aging2021 to 2025$11,494,462February 1, 2021January 31, 2027RAMOS, ALBERTO RAFAELreporter.nih.gov
Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population StudyNIHNational Institute on Aging2021 to 2025$11,418,675September 1, 2021May 31, 2027RAJAN, KUMAR B.reporter.nih.gov
Genomic Characterization of Alzheimer Disease Risk in Admixed Populations with Native American and Southern European Genetic AncestryNIHNational Institute on Aging2021 to 2025$11,411,820February 1, 2021January 31, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$11,402,108September 30, 2004May 31, 2027BARNES, LISA Lreporter.nih.gov
Complement Mediated Remodeling in Pulmonary Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$11,355,302August 1, 2020June 30, 2026STENMARK, KURT R.reporter.nih.gov
Remote Monitoring and Virtual Collaborative Care for Hypertension Control to Prevent Cognitive DeclineNIHNational Institute on Aging2021 to 2024$11,354,079August 1, 2020July 31, 2025GUPTA, ADITIreporter.nih.gov
Circuit-specific cell types in aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$11,340,010June 1, 2022May 31, 2028LEE, KUO-FENreporter.nih.gov
Whole Genome Sequencing and Admixture Analyses of Neuropathologic Traits in Diverse Cohorts in USA and BrazilNIHNational Institute on Aging2023 to 2025$11,334,713August 15, 2023July 31, 2028BENNETT, DAVID ALANreporter.nih.gov
Pre-Symptomatic Familial ALS (Pre-fALS) Study: From Prodrome and Biomarkers to ALS/FTD PreventionNIHNational Institute of Neurological Disorders and Stroke2025$11,282,768September 15, 2018July 31, 2029BENATAR, MICHAELreporter.nih.gov
The Longitudinal Course of Imaging Biomarkers in People At Risk for Alzheimer’s DiseaseNIHNational Institute on Aging2022 to 2025$11,223,576August 15, 2004March 31, 2027JOHNSON, STERLING Creporter.nih.gov
KBASE2: Korean Brain Aging Study, Longitudinal Endophenotypes and Systems BiologyNIHNational Institute on Aging2021 to 2025$11,202,386August 15, 2021July 31, 2027SAYKIN, ANDREW Jreporter.nih.gov
Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$10,898,840May 15, 2022April 30, 2027XU, XIANGMINreporter.nih.gov
A Seamless Phase 2A-B Randomized Double Blind Placebo Controlled Trial to Evaluate the Efficacy and Safety of PQ 912 in Patients with Early Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$10,874,349April 1, 2019June 30, 2025FELDMAN, HOWARDreporter.nih.gov
Longitudinal Imaging Biomarkers of Prodromal DLBNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,821,041September 25, 2017August 31, 2027KANTARCI, KEJALreporter.nih.gov
Blood amyloid, tau, and neurodegeneration biomarkers and prediction of clinical onset, cognitive decline, and dementia diagnosisNIHNational Institute on Aging2024 to 2025$10,584,728September 30, 2008May 31, 2029BATEMAN, RANDALL Jreporter.nih.gov
Arterial Stiffness, Cognition, and Equol (ACE)NIHNational Institute on Aging2022 to 2025$10,581,052February 15, 2022January 31, 2027SEKIKAWA, AKIRAreporter.nih.gov
VCID Biomarkers Coordinating CenterNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$10,493,954September 30, 2016June 30, 2027GREENBERG, STEVEN Mreporter.nih.gov
The INCLUDE Project Down Syndrome Biorepository (DS-Biorepository)NIHNational Institute on Aging2024 to 2025$10,436,444September 30, 2024August 31, 2029ESPINOSA, JOAQUIN M.reporter.nih.gov
Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.NIHNational Institute on Aging2022 to 2025$10,320,460February 15, 2022January 31, 2027AGADJANYAN, MICHAEL Greporter.nih.gov
BRAIN-ICU-2 Study: Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction (Dementia) in ICU Survivors, 2nd StudyNIHNational Institute on Aging2021 to 2024$10,318,677April 15, 2019January 31, 2026ELY, E WESLEYreporter.nih.gov
Alzheimer's Disease and Related Dementias (ADRD) prevalence in American SamoaNIHNational Institute on Aging2022 to 2025$10,293,481September 30, 2022August 31, 2027TOFAEONO, VAATAUSILI Treporter.nih.gov
NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)NIHNational Center for Complementary & Integrative Health2021 to 2025$10,249,994September 22, 2022May 31, 2028HERNANDEZ, ADRIANreporter.nih.gov
Vermont Center for Cardiovascular and Brain HealthNIHNational Institute of General Medical Sciences2021 to 2024$10,185,844August 6, 2020May 31, 2026CUSHMAN, MARYreporter.nih.gov
ACTIVE MIND: An adaptive clinical trial of cognitive training to improve function and delay dementiaNIHNational Institute on Aging2022 to 2023$10,112,651September 1, 2022June 24, 2024O'BRIEN, JENNIFER LEEreporter.nih.gov
Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and SusceptibilityNIHNational Institute on Aging2021 to 2024$9,901,034May 1, 2021February 28, 2026REDLINE, SUSAN S.reporter.nih.gov
Life’s end Benefits of CannaBidol and TetrahYdrocannabinol (LiBBY) TrialNIHNational Institute on Aging2021 to 2022$9,892,823September 15, 2020April 30, 2026MINTZER, JACOBOreporter.nih.gov
Gateway Exposome Coordinating Center (GECC) For AD/ADRD ResearchNIHNational Institute on Aging2024 to 2025$9,887,007August 1, 2024July 31, 2029LEE, JINKOOKreporter.nih.gov
Vanderbilt Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,726,538December 1, 1996March 31, 2027POWERS, ALVIN Creporter.nih.gov
DEploying High ValuE LOngitudinal Population-Based dAta in Dementia Research (DEVELOP AD Research)NIHNational Institute on Aging2021 to 2024$9,684,597September 30, 2020May 31, 2026MORRISON, R. SEANreporter.nih.gov
Study to Uncover Pathways to Exceptional Cognitive Resilience in Aging (SUPERAging)NIHNational Institute on Aging2023 to 2025$9,673,461September 30, 2021August 31, 2027ROGALSKI, EMILY Jreporter.nih.gov
National Swine Resource and Research Center (NSRRC) Years 21-25NIHOffice of the Director, National Institutes of Health2021 to 2025$9,635,041September 1, 2003July 31, 2028LEE, KIHOreporter.nih.gov
TASK ORDER 1 - OCR PROJECT MANAGEMENT, DSMB AND CROMS-RELATED SUPPORTNIHNational Institute on Drug Abuse2024 to 2025$9,613,167March 25, 2024March 24, 2026APPELMANS, ELINEreporter.nih.gov
Collaborative Approach for Asian Americans, Native Hawaiians, and Pacific Islanders Research and Education (CARE) 2.0NIHNational Institute on Aging2023 to 2025$9,607,843August 1, 2023June 30, 2028PARK, VAN MY TAreporter.nih.gov
Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid and Tau in Older Adults (IPAT-study)NIHNational Institute on Aging2022 to 2025$9,488,371August 1, 2022July 31, 2027ZHANG, RONGreporter.nih.gov
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a TrialNIHNational Institute on Aging2021 to 2025$9,481,336February 15, 2021November 30, 2026HANLEY, DANIEL Freporter.nih.gov
Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)NIHNational Institute on Aging2025$9,466,491September 1, 2023August 31, 2028STONE, KATIE Lreporter.nih.gov
Tulane COBRE for Clinical and Translational Research in Cardiometabolic DiseasesNIHNational Institute of General Medical Sciences2022 to 2025$9,439,774March 10, 2016June 30, 2027MILLS, KATHERINE TERESAreporter.nih.gov
Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSPNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,418,230September 1, 2021August 31, 2026GOATE, ALISON Mreporter.nih.gov
TO ADMINISTRATIVELY DE-OBLIGATE UNEXPENDED AND EXPIRING FISCAL YEAR 2020 FUNDING IN ACCORDANCE WITH 31 U.S.C. SECTION 1552 (A), IN PREPARATION FOR SEPTEMBER 30, 2025, CLOSING OF THE PERIOD OF AVAILABINIHOffice of the Director, National Institutes of Health2021 to 2025$9,377,344May 1, 2025October 31, 2025reporter.nih.gov
Genetic Epidemiology and Multi-Omics Analyses in Familial and Sporadic Alzheimer's Disease Among Secular Caribbean Hispanics and Religious OrderNIHNational Institute on Aging2021 to 2024$9,373,073June 1, 2020March 31, 2026MAYEUX, RICHARD Preporter.nih.gov
The San Antonio Heart and Mind StudyNIHNational Institute on Aging2023 to 2025$9,286,743July 1, 2023March 31, 2029SATIZABAL, CLAUDIA Lreporter.nih.gov
African Americans Fighting Alzheimer’s in Midlife (AA-FAIM)NIHNational Institute on Aging2021 to 2025$9,250,399August 1, 2016November 30, 2027GLEASON, CAREY Ereporter.nih.gov
Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN CohortNIHNational Institute on Aging2021 to 2025$9,240,061August 1, 2017December 31, 2027YASSA, MICHAEL Areporter.nih.gov
The Care Ecosystem Response to COVID-19: Accelerating Research on Dementia Care that Meets the Needs of Caregivers and Persons with Dementia during COVID-19NIHNational Institute on Aging2022 to 2024$9,143,854June 15, 2022May 31, 2026POSSIN, KATHERINE LAURELreporter.nih.gov
Identification of TDP-43 Modifiers Through Single-Cell Transcriptional and Epigenomic Dissection of ALS and FTLD-MNDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,106,321September 29, 2021August 31, 2026DONNELLY, CHRISTOPHER JAMESreporter.nih.gov
Center of Excellence in Environmental ToxicologyNIHNational Institute of Environmental Health Sciences2021 to 2025$9,096,433April 1, 2006May 31, 2030PENNING, TREVOR Mreporter.nih.gov
Resilience and brain health of older adultsNIHNational Institute on Aging2021 to 2025$9,066,206August 15, 2021May 31, 2027LENZE, ERIC Jreporter.nih.gov
NATIONAL NEUROHIV TISSUE CONSORTIUM (NNTC) - CLINICAL SITE - Alzheimer's diseaseNIHNational Institute of Mental Health2023 to 2025$9,005,480August 23, 2023August 22, 2026HADIJAH, VACTORreporter.nih.gov
Epidemiologic Study of Neural Reserve and Neurobiology of AgingNIHNational Institute on Aging2021 to 2023$8,995,869September 30, 2001May 31, 2026BENNETT, DAVID ALANreporter.nih.gov
Center for Stress and Neural Regulation of Reproductive Aging Health OutcomesNIHNational Institute on Aging2021 to 2025$8,986,759June 1, 2020August 31, 2030JOFFE, HADINEreporter.nih.gov
Consequences of Incarceration on Health, Age-Related Conditions, and Risk Factors for ADRDNIHNational Institute on Aging2024 to 2025$8,887,003August 15, 2024April 30, 2029TEPLIN, LINDA Areporter.nih.gov
Johns Hopkins-Tufts Trial Innovation Center HEAL Pain ERN SupplementNIHNational Center for Advancing Translational Sciences2021 to 2022$8,842,412July 1, 2016June 30, 2023HANLEY, DANIEL Freporter.nih.gov
Risk Factors, Pathology, and Clinical Expressions of ADNIHNational Institute on Aging2021 to 2024$8,703,055July 15, 1998April 30, 2026BENNETT, DAVID ALANreporter.nih.gov
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular InteractionsNIHNational Institute on Aging2021 to 2025$8,654,669July 1, 2021June 30, 2027TEMPLE, SALLYreporter.nih.gov
Educational and Early Life Predictors of Mild Cognitive Impairment: New Evidence about Mediators and Moderators from High School & BeyondNIHNational Institute on Aging2023 to 2024$8,554,832May 15, 2019February 28, 2026WARREN, JOHN ROBERTreporter.nih.gov
P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in IndiaNIHNational Institute on Aging2024 to 2025$8,548,820September 15, 2024August 31, 2029NARAYAN, KABAYAM M VENKATreporter.nih.gov
Alzheimer variants: Propagation of shared functional changes across cellular networksNIHNational Institute on Aging2021 to 2025$8,542,236July 15, 2021June 30, 2027DE JAGER, PHILIP Lreporter.nih.gov
Preserving Cognitive Resilience: A Biracial Parent-Offspring StudyNIHNational Institute on Aging2022 to 2024$8,461,054March 1, 2019May 31, 2026RAJAN, KUMAR B.reporter.nih.gov
Functional Genomic Dissection of Alzheimer's Disease in Humans and Drosophila ModelsNIHNational Institute on Aging2021 to 2025$8,376,812July 1, 2021June 30, 2026SHULMAN, JOSHUA Mreporter.nih.gov
Genetic Architecture of Alzheimer’s disease ProteinopathiesNIHNational Institute on Aging2021 to 2024$8,376,544April 15, 2021February 28, 2026KAMBOH, M. ILYASreporter.nih.gov
Genetic Studies of Alzheimer's Disease in Jewish and Arab PopulationsNIHNational Institute on Aging2023 to 2025$8,372,205September 1, 2023August 31, 2028FARRER, LINDSAY A.reporter.nih.gov
Longitudinal validation of retinal biomarkers against cerebral imaging in preclinical Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$8,348,817September 15, 2022May 31, 2027ALBER, JESSICAreporter.nih.gov
ASYMMETRIC NEURODEGENERATION AND LANGUAGE IN PRIMARY PROGRESSIVE APHASIANIHNational Institute on Aging2022 to 2025$8,306,361June 15, 2022March 31, 2027MESULAM, MAREK-MARSEL Mreporter.nih.gov
Multi-omic functional assessment of novel AD variants using high-throughput and single-cell technologiesNIHNational Institute on Aging2021 to 2025$8,305,058July 1, 2021June 30, 2026MONTINE, THOMAS Jreporter.nih.gov
Exceptional Longevity Data Management and Coordinating CenterNIHNational Institute on Aging2022 to 2025$8,296,806September 1, 2022July 31, 2027VARMA, SUSHEELreporter.nih.gov
A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$8,293,749September 30, 2021August 31, 2026ZAIDI, MONEreporter.nih.gov
Gulf Coast Center for Precision Environmental HealthNIHNational Institute of Environmental Health Sciences2021 to 2025$8,275,327May 15, 2019May 31, 2029WALKER, CHERYL L.reporter.nih.gov
Manufacturing of Drug Product, Dual Aβ/tau Vaccine for Clinical TrialsNIHNational Institute on Aging2021 to 2023$8,244,109February 1, 2019January 31, 2025AGADJANYAN, MICHAEL Greporter.nih.gov
The Physical Biology of Neurodegeneration in Sporadic Amyotrophic Lateral Sclerosis/Frontotemporal DementiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$8,227,499September 1, 2021August 31, 2027PHATNANI, HEMALIreporter.nih.gov
GLASS-AD: Global Latinos Sequencing Study for Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$8,212,071September 30, 2023August 31, 2028TOSTO, GIUSEPPEreporter.nih.gov
Race / Ethncicity, Hypertension and Prevention of VCID and Stroke after Intracerebral HemmorrhageNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,210,604February 1, 2016July 31, 2027ROSAND, JONATHANreporter.nih.gov
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targetsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$8,189,971September 15, 2024August 31, 2026GITLER, AARON D.reporter.nih.gov
Emergency General Surgery Delirium Recovery Model: A Collaborative Care InterventionNIHNational Institute on Aging2022 to 2025$8,173,947July 1, 2022June 30, 2027ZARZAUR, BEN Lreporter.nih.gov
Disordered Proteostasis as a Driver of Disease in the Aging LungNIHNational Institute on Aging2021 to 2024$8,161,610July 1, 2015March 31, 2025BUDINGER, GR SCOTTreporter.nih.gov
Alzheimer's Prevention Initiative ADAD Colombia TrialNIHNational Institute on Aging2021 to 2022$8,118,116April 1, 2017September 30, 2024REIMAN, ERIC MICHAELreporter.nih.gov
Racial/Ethnic Disparities in ADRD Risk: The Impact of Social RelationsNIHNational Institute on Aging2021 to 2024$8,105,276June 1, 2020March 31, 2026ANTONUCCI, TONI CLAUDETTEreporter.nih.gov
Characterizing the Genetic Risk for Alzheimer Disease in African and Admixed African-American AncestriesNIHNational Institute on Aging2024 to 2025$8,032,655September 30, 2024August 31, 2029GRISWOLD, ANTHONY JOHNreporter.nih.gov
Addressing Alzheimer's Disease and Related Dementias Disparities: The American Indigenous Cognitive Assessment (AMICA) ProjectNIHNational Institute on Aging2022 to 2025$7,983,648June 1, 2022May 31, 2027JACKLIN, KRISTENreporter.nih.gov
CHARTER Plus: A resource for cutting-edge research on neurological function and mental health in people with HIV and substance use disorders across the lifespanNIHNational Institute of Mental Health2022 to 2025$7,973,681February 1, 2022November 30, 2026LETENDRE, SCOTT Lreporter.nih.gov
Indiana Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,959,091July 6, 2015May 31, 2030EVANS-MOLINA, CARMELLAreporter.nih.gov
THE NIH PRECISION BRAIN HEALTH NETWORK: Open and Inclusive Measurement of Neuropsychological Change for AD/ADRD Primary Prevention TrialsNIHNational Institute on Aging2025$7,948,867August 1, 2025July 31, 2030SLIWINSKI, MARTIN Jreporter.nih.gov
Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasiaNIHNational Institute on Aging2023 to 2025$7,878,167September 15, 2017August 31, 2028ROGALSKI, EMILY Jreporter.nih.gov
Higher Order Chromatin and Genetic Risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$7,828,464September 1, 2015May 31, 2027ROUSSOS, PANAGIOTISreporter.nih.gov
Claude D. Pepper Older Americans Independence Center at YaleNIHNational Institute on Aging2021 to 2025$7,769,010September 30, 2002June 30, 2028GILL, THOMAS MICHAELreporter.nih.gov
ERICH-GENENIHNational Institute of Neurological Disorders and Stroke2021 to 2024$7,768,356August 1, 2010June 30, 2025DEMEL, STACIEreporter.nih.gov
The POINTER Neurovascular Ancillary StudyNIHNational Institute on Aging2021 to 2024$7,761,498April 15, 2020December 31, 2025BRINKLEY, TINA Ereporter.nih.gov
Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2021 to 2025$7,757,977July 1, 2021June 30, 2027KAYED, RAKEZreporter.nih.gov
Mapping the vulnerable locus coeruleus pathways in aging and ADNIHNational Institute on Aging2022 to 2025$7,731,727August 15, 2022July 31, 2027CHUNG, KWANGHUNreporter.nih.gov
SCAN: Standardized Centralized Alzheimer's and Related Dementias NeuroimagingNIHNational Institute on Aging2021 to 2025$7,600,838May 1, 2020April 30, 2027JAGUST, WILLIAM J.reporter.nih.gov
Vietnamese Insights into Cognitive Aging Program (VIP)NIHNational Institute on Aging2021 to 2025$7,598,841February 15, 2021May 31, 2026MEYER, OANH Lreporter.nih.gov
Look AHEAD Sleep: Sleep-disordered breathing, circadian rest/activity rhythms, and the risk of Alzheimer's disease and related dementias in Look AHEADNIHNational Institute on Aging2021 to 2025$7,592,411August 15, 2021May 31, 2027UDEH-MOMOH, CHINEDU THERESAreporter.nih.gov
Genotyping the Understanding America Study to generate novel opportunities for research on cognitive functioning and dementiaNIHNational Institute on Aging2023 to 2025$7,564,979September 15, 2023May 31, 2028GALAMA, TITUS JOHANNESreporter.nih.gov
THE PURPOSE OF THIS CONTRACT IS TO ESTABLISH COLLECTION SITE(S) (I.E., THE NIH BRAIN AND TISSUE REPOSITORY (NBTR) TO PROVIDE SERVICES THAT WILL ACTIVELY ACQUIRE, RECEIVE, STORE, CURATE, PRESERVE, ANDNIHNational Institute on Drug Abuse2021 to 2025$7,530,975May 1, 2025October 31, 2025SCOTT, WILLIAMreporter.nih.gov
A major contributor of serious multisystem disease in the elderly: varicella zoster virus-induced inflammationNIHNational Institute on Aging2021 to 2023$7,526,233March 1, 2009December 31, 2025NAGEL, MARIA ACENAreporter.nih.gov
Plasma Proteomic Signatures for Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2022$7,523,227September 15, 2022August 31, 2025SHADYAB, ALADDINreporter.nih.gov
REpeated ASseSsmEnt of SurvivorS in ICH (REASSESS ICH)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$7,516,765January 1, 2022December 31, 2027ZIAI, WENDY Creporter.nih.gov
Indigenous Cultural Understandings of Alzheimer's Disease and Related Dementias - Research and Engagement (I-CARE)NIHNational Institute on Aging2021 to 2025$7,489,463March 1, 2021February 28, 2027JACKLIN, KRISTENreporter.nih.gov
Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2024$7,486,964February 15, 2020January 31, 2026ROUSSOS, PANAGIOTISreporter.nih.gov
A randomized, placebo-controlled, double-blind study to evaluate safety and efficacy of NDX-1017 treatment in Alzheimer's dementia patientsNIHNational Institute on Aging2021 to 2022$7,416,643September 15, 2020May 31, 2023MOEBIUS, HANS JOERGreporter.nih.gov
Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and ResilienceNIHNational Institute on Aging2021 to 2024$7,413,273September 15, 2020May 31, 2025SESHADRI, SUDHAreporter.nih.gov
Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)NIHNational Institute on Aging2023 to 2024$7,403,993September 1, 2023August 31, 2028STONE, KATIE Lreporter.nih.gov
CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2025$7,389,501January 15, 2021December 31, 2026RAO, STEPHEN MARKreporter.nih.gov
Therapeutics targeting TDP-43 to treat Alzheimer's disease and related disordersNIHNational Institute on Aging2021 to 2025$7,375,647July 1, 2021December 31, 2026REITZ, ALLEN BERNARDreporter.nih.gov
Predictors of Altered CNS Structure, Function, and Connectomics in the Elderly using a Health Disparities FrameworkNIHNational Institute on Aging2022 to 2025$7,350,257February 15, 2022November 30, 2027COHEN, ANN D.reporter.nih.gov
Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS II)NIHNational Institute on Aging2024 to 2025$7,286,036June 15, 2024November 30, 2029JOHNSON-AKEJU, OLUWASEUNreporter.nih.gov
Leveraging the 24-hour movement paradigm to preserve cognitive function and prevent Alzheimer's disease: The Multi-Ethnic Study of Atherosclerosis (MESA) 24H-ACT StudyNIHNational Institute on Aging2021 to 2024$7,263,372May 1, 2021April 30, 2026DIAZ, KEITH Mreporter.nih.gov
The VETSA Longitudinal MRI Twin Study of Aging (VETSA MRI 4)NIHNational Institute on Aging2022 to 2025$7,252,240June 1, 2022March 31, 2027ELMAN, JEREMY Areporter.nih.gov
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy AgingNIHNational Institute on Aging2022 to 2025$7,239,829August 15, 2022June 30, 2027CRUCHAGA, CARLOSreporter.nih.gov
Aging eyes and aging brains in studying alzheimer''s disease: Modern ophthalmic data collection in the adult changes in thought (ACT) studyNIHNational Institute on Aging2025$7,155,353September 1, 2019April 30, 2029LEE, CECILIA SUNGMINreporter.nih.gov
Genetics of deep-learning-derived neuroimaging endophenotypes for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$7,153,018July 1, 2021June 30, 2027ZHI, DEGUIreporter.nih.gov
Escitalopram for Agitation in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2022$7,145,681September 30, 2016May 31, 2024LYKETSOS, CONSTANTINE Greporter.nih.gov
Developing a NAMPT activator for Alzheimer’s diseaseNIHNational Institute on Aging2023 to 2025$7,056,557September 15, 2023August 31, 2028CHEN, BEIBEIreporter.nih.gov
Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2023$7,036,460September 15, 2019May 31, 2025ROUSSOS, PANAGIOTISreporter.nih.gov
Integrating the exposome and methylome to inform brain molecular changes in ADRD across established diverse cohorts.NIHNational Institute on Aging2021 to 2022$6,989,910September 1, 2020August 31, 2025ERTEKIN-TANER, NILUFERreporter.nih.gov
University of Maryland Claude D. Pepper Older Americans Independence Center (OAIC)NIHNational Institute on Aging2021 to 2025$6,970,364September 15, 2006June 30, 2027RYAN, ALICE S.reporter.nih.gov
UCSF Older Americans Independence CenterNIHNational Institute on Aging2021 to 2025$6,946,581July 15, 2013June 30, 2028COVINSKY, KENNETH E.reporter.nih.gov
Multidimensional mapping of vulnerable cell types in humanized Alzheimer's disease mouse modelsNIHNational Institute on Aging2023 to 2025$6,945,316July 1, 2023March 31, 2028COBOS, INMAreporter.nih.gov
Differential Effects of Exercise Modality on Cognition and Brain in Older AdultsNIHNational Institute on Aging2021 to 2025$6,923,080April 1, 2021March 31, 2027VIDONI, ERIC DENNISreporter.nih.gov
Risk Factors for Future Cognitive Decline and Alzheimers Disease in Older African AmericansNIHNational Institute on Aging2021 to 2025$6,919,789May 15, 2018May 31, 2028GLUCK, MARK Areporter.nih.gov
Functional genomic studies in diverse populations to characterize risk loci for Alzheimer DiseaseNIHNational Institute on Aging2021 to 2025$6,908,458July 15, 2021June 30, 2027VANCE, JEFFERY MARVINreporter.nih.gov
Lifetime stressors and Alzheimer's Disease genetic variants and biomarkers in relation to cognitive decline among Black Women'sHealth Study participants.NIHNational Institute on Aging2024 to 2025$6,906,113February 15, 2024January 31, 2029ROSENBERG, LYNNreporter.nih.gov
Clinical trials to prevent Alzheimer's Disease in Down SyndromeNIHNational Institute on Aging2022 to 2024$6,863,895September 15, 2019August 31, 2025RAFII, MICHAEL Sreporter.nih.gov
GMP Production and Extended Toxicology of an Oral Formulation Drug for Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$6,827,181June 1, 2022May 31, 2027WATTERSON, DANIEL MARTINreporter.nih.gov
The adaptive-innate immune interactome across multiple tissues in Alzheimer's diseaseNIHNational Institute on Aging2023 to 2025$6,770,771May 15, 2023January 31, 2028ROUSSOS, PANAGIOTISreporter.nih.gov
Examining the Persistence of Neurocognitive Benefits of ExerciseNIHNational Institute on Aging2023 to 2025$6,759,799September 1, 2023May 31, 2028ERICKSON, KIRK Ireporter.nih.gov
Artificial Intelligence Strategies for Alzheimer's Disease ResearchNIHNational Institute on Aging2022 to 2025$6,749,268September 30, 2021August 31, 2026MOORE, JASON H.reporter.nih.gov
North Carolina Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,742,732April 7, 2020May 31, 2028NEUFER, P DARRELLreporter.nih.gov
Adapting the ShedMEDS Deprescribing Intervention to Dementia Care in Assisted LivingNIHNational Institute on Aging2021 to 2023$6,628,141August 15, 2019July 31, 2024STEINMAN, MICHAEL A.reporter.nih.gov
Developing Novel Soluble Epoxide Hydrolase Inhibitors for the Treatment of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2024$6,621,893September 15, 2020May 31, 2026WANG, JINreporter.nih.gov
Cell Specific Perturbations of the Proteome in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$6,610,744September 30, 2021July 31, 2027YATES III, JOHN Rreporter.nih.gov
Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,609,782September 30, 2014August 31, 2030BENATAR, MICHAELreporter.nih.gov
A Pragmatic Trial of the UCSF Brain Health Assessment for the Detection of Cognitive Impairment in Primary CareNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$6,593,404September 15, 2022August 31, 2027POSSIN, KATHERINE LAURELreporter.nih.gov
Precision Editing of Granulin Mutations that Cause Frontotemporal DementiaNIHNational Institute of Neurological Disorders and Stroke2025$6,580,415August 15, 2025July 31, 2029SONTHEIMER, ERIK J.reporter.nih.gov
Life-course social adversity, pesticide exposure, and cognitive outcomes among an ongoing cohort of mid-life Latina women in an under served agricultural regionNIHNational Institute on Aging2021 to 2024$6,569,013September 15, 2020May 31, 2026TORRES, JACQUELINE MARIEreporter.nih.gov
Dementia with Lewy Bodies ConsortiumNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$6,563,373September 30, 2016August 31, 2027LEVERENZ, JAMES BRUCEreporter.nih.gov
Technology to Realize the Full Potential of UHF MRINIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$6,553,989February 1, 2019January 31, 2029METZGER, GREGORY JOHNreporter.nih.gov
The RAW Brain - The Effect of Rumination, Anxiety and Worry on Aging and Dementia RiskNIHNational Institute of Mental Health2021 to 2025$6,507,641September 20, 2016June 30, 2027ANDREESCU, CARMENreporter.nih.gov
The effects of Alzheimer's disease risk genes on metabolism and signaling across cell typesNIHNational Institute on Aging2022 to 2025$6,477,664September 19, 2022August 31, 2027FRAENKEL, ERNESTreporter.nih.gov
Extracranial Carotid Atherosclerosis Contributions to Cognitive Impairment and Alzheimer's Disease RiskNIHNational Institute on Aging2021 to 2025$6,475,434August 15, 2021May 31, 2027WEINKAUF, CRAIG Creporter.nih.gov
The Ante-Amyloid Treatment of Alzheimer's disease (A3) Trial and Alzheimer Plasma EXtension (APEX) StudyNIHNational Institute on Aging2025$6,467,513September 1, 2025August 31, 2030SPERLING, REISA A.reporter.nih.gov
The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center studyNIHNational Institute on Aging2021 to 2024$6,442,962June 15, 2020March 31, 2025VERGHESE, JOEreporter.nih.gov
Trends and Dynamics in Caregiving for Alzheimer’s Disease and Related Dementias: Extending the National Study of CaregivingNIHNational Institute on Aging2021 to 2023$6,436,858June 15, 2019May 31, 2026FREEDMAN, VICKI A.reporter.nih.gov
Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman PrimatesNIHNational Institute on Aging2025$6,424,607September 15, 2025September 14, 2029BAXTER, MARK Greporter.nih.gov
Contributions of stress reactivity to risk of Alzheimer's disease and related dementia's in a community-based cohortNIHNational Institute on Aging2021 to 2025$6,416,931September 30, 2021May 31, 2027KERSHAW, KIARRI Nreporter.nih.gov
Validation of the Remote Cognitive Aging and Alzheimer’s Disease REsearch (R-CARE) Toolbox for Diverse PopulationsNIHNational Institute on Aging2023 to 2025$6,381,700August 15, 2023May 31, 2028LIPTON, RICHARD B.reporter.nih.gov
Protective Genetic Variants for Alzheimer Disease in the Amish - RENEWALNIHNational Institute on Aging2022 to 2025$6,381,039September 1, 2022May 31, 2027HAINES, JONATHAN Lreporter.nih.gov
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2024$6,353,055May 15, 2020April 30, 2026TSAI, LI-HUEIreporter.nih.gov
Cerebral small vessel disease burden and racial disparity in vascular cognitive impairment and Alzheimer’s disease and its related dementiasNIHNational Institute on Aging2021 to 2025$6,336,090September 15, 2021May 31, 2027HYACINTH, HYACINTH IDUreporter.nih.gov
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationNIHNational Institute on Aging2021 to 2025$6,330,805June 15, 2018May 31, 2028LAI, JENNIFER C.reporter.nih.gov
A Life Course Approach to Integrating Trauma and Cognitive Aging: A Cohort of 9/11 RespondersNIHNational Institute on Aging2021 to 2024$6,329,240May 15, 2015April 30, 2026CLOUSTON, SEANreporter.nih.gov
Elevated FSH - A Driver for Sex Differences in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$6,313,088September 30, 2021August 31, 2026ZAIDI, MONEreporter.nih.gov
Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project IINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$6,308,426August 15, 2024July 31, 2029ALOSCO, MICHAELreporter.nih.gov
PhytoSERM Efficacy to Prevent Menopause Associated Decline in Brain Metabolism and Cognition: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical TrialNIHNational Institute on Aging2022 to 2025$6,295,083February 15, 2022January 31, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
Phase II trial of GM-CSF/sargramostim in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$6,265,868February 1, 2021November 30, 2026POTTER, HUNTINGTONreporter.nih.gov
The NH Explanatory Trials Network: Supporting Transformation by Enhancing Partnerships (The NEXT STEPS).NIHNational Institute on Aging2024 to 2025$6,261,370September 1, 2024May 31, 2029UNROE, KATHLEEN Treporter.nih.gov
Validation of Biomarkers of Small Vessel Injury in VCIDNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,258,167September 29, 2021July 31, 2026ROSENBERG, GARY ALLENreporter.nih.gov
Longitudinal Examination of Neighborhood Disadvantage, Cognitive Aging, and Alzheimer's Disease Risk in Disinvested, African American NeighborhoodsNIHNational Institute on Aging2022 to 2024$6,229,431February 15, 2022January 31, 2025DUBOWITZ, TAMARAreporter.nih.gov
Washington University University of Texas Southwestern VCID Consortium SiteNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,224,729September 29, 2021July 31, 2026LEE, JIN-MOOreporter.nih.gov
Expanding insights into FTD disease mechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$6,199,699December 1, 2016November 30, 2024PETRUCELLI, LEONARDreporter.nih.gov
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related DementiaNIHNational Institute on Aging2021 to 2023$6,168,197April 15, 2020March 31, 2024HAY, MEREDITHreporter.nih.gov
Traumatic Brain Injury and Repetitive Head Impacts: Contributions to AD/ADRD and CTE Neuropathology and Resulting Clinical SyndromesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,142,337September 30, 2019July 31, 2025MCKEE, ANN C.reporter.nih.gov
Imaging Genetics of Brain Structure and Cognitive Aging in Murine Models of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$6,121,279February 1, 2021January 31, 2027WILLIAMS, ROBERT W.reporter.nih.gov
The University of Kentucky MarkVCID Biomarker Validation Cohort: Development of a Toolbox to Advance VCID Interventional StudiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,120,000September 29, 2021July 31, 2026JICHA, GREGORY Areporter.nih.gov
Elucidate the roles of Alzheimer's disease risk genes and variants in gene expression and AD-related phenotypesNIHNational Institute on Aging2022 to 2025$6,109,739September 15, 2022August 31, 2027SHEN, YINreporter.nih.gov
Establishing the science behind Alzheimer's recruitment registries: opportunities for increasing diversity and accelerating enrollment into trialsNIHNational Institute on Aging2021 to 2023$6,105,662September 1, 2019March 21, 2025LANGBAUM, JESSICA BROOKEreporter.nih.gov
MarkVCID Validation in the General CommunityNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,100,999September 23, 2021July 31, 2026PETERSEN, RONALD Creporter.nih.gov
Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regionsNIHNational Institute on Aging2023 to 2025$6,093,858June 1, 2023February 29, 2028XU, XIANGMINreporter.nih.gov
Long-Term Nicotine Treatment of Mild Cognitive ImpairmentNIHNational Institute on Aging2022$6,088,879September 15, 2015January 31, 2026NEWHOUSE, PAUL A.reporter.nih.gov
Biomarker Evaluation in Young Onset Dementia from Diverse Populations (BEYONDD)NIHNational Institute on Aging2022$6,065,228September 15, 2022August 31, 2025BOXER, ADAM L.reporter.nih.gov
CNS Mechanisms Linking Exercise Training with Energy Balance and MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$6,058,407September 20, 2019August 31, 2025ELMQUIST, JOEL K.reporter.nih.gov
Diagnosis and Risk factors of hippocampal sclerosis of aging and limbic predominant age related TDP-43 encephalopathy; common Alzheimer’s mimicsNIHNational Institute on Aging2021 to 2025$6,052,469April 1, 2019May 31, 2029SAJJADI, SEYED AHMADreporter.nih.gov
Effectiveness of Implementing an Intensive Blood Pressure Reduction Intervention on Cognitive Decline in Low-income and Minority Hypertensive PatientsNIHNational Institute on Aging2021 to 2024$6,046,063August 1, 2020July 31, 2025MILLS, KATHERINE TERESAreporter.nih.gov
Delirium, Dementia, and the Vulnerable Brain: An Integrative ApproachNIHNational Institute on Aging2021 to 2022$6,002,449September 15, 2018May 31, 2024INOUYE, SHARON K.reporter.nih.gov
Decoding the impact of sex differences on Alzheimer's disease riskNIHNational Institute on Aging2021 to 2025$5,985,073September 15, 2021June 30, 2027LICHTARGE, OLIVIERreporter.nih.gov
Development of novel NLRP3 inflammasome inhibitors for intervening in Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$5,966,043June 1, 2022May 31, 2027ZHANG, SHIJUNreporter.nih.gov
Impact of sex differences on the trajectory of interactome dysfunctions across the AD spectrumNIHNational Institute on Aging2021 to 2025$5,959,465September 15, 2021May 31, 2027CHIOSIS, GABRIELAreporter.nih.gov
VCID CWOW: Identifying Novel Targets to Treat Cerebral Amyloid AngiopathyNIHNational Institute of Neurological Disorders and Stroke2024$5,949,022September 18, 2024August 31, 2027HOWELL, GARETH Rreporter.nih.gov
Integration of immune cell subtypes across diseases & tissueNIHNational Institute on Aging2021 to 2022$5,948,190September 30, 2018August 31, 2023DE JAGER, PHILIP Lreporter.nih.gov
URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related DementiasNIHNational Institute on Aging2021 to 2024$5,941,036September 1, 2019May 31, 2026NELSON, LONNIE A.reporter.nih.gov
Dissecting the role of sex-linked genes and APOE e4 risk in ADNIHNational Institute on Aging2021 to 2025$5,928,484September 30, 2021July 31, 2027YOUNG, JESSICA ELAINEreporter.nih.gov
Chaperome networks in Alzheimer's diseaseNIHNational Institute on Aging2021 to 2025$5,927,093February 15, 2021January 31, 2027CHIOSIS, GABRIELAreporter.nih.gov
Penn PET Addiction Center of Excellence (PACE)NIHNational Institute on Drug Abuse2021 to 2023$5,914,143August 15, 2019June 30, 2025MACH, ROBERT Hreporter.nih.gov
THE PURPOSE OF THIS TASK ORDER IS TO PROVIDE THE NATIONAL INSTITUTE ON AGING WITH INFORMATION RESOURCE CENTER SERVICES IN ACCORDANCE WITH THE ATTACHED STATEMENT OF WORK AND QUOTE DATED 8/1/2025.NIHNational Institute on Drug Abuse2024 to 2025$5,908,784September 16, 2025September 15, 2026reporter.nih.gov
PNA5: A Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Vascular Dementia and Alzheimer's Disease Related Dementia: an FDA required Toxicology StudyNIHNational Institute on Aging2023 to 2025$5,906,221September 1, 2023August 31, 2027HAY, MEREDITHreporter.nih.gov
Novel Reengineered Microbiome-based Biologic Therapy to Treat Cognitive and Behavioral Symptoms of Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2022 to 2025$5,896,816August 15, 2022May 31, 2027KANTHASAMY, ANUMANTHA GOUNDERreporter.nih.gov
Late-onset Unexplained Epilepsy as a Risk Factor for DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$5,883,988September 1, 2023February 28, 2029LAM, ALICE Dreporter.nih.gov
A Proteomic Comparison of Sporadic Early-Onset, Late-Onset, and Autosomal Dominant Alzheimer's DiseaseNIHNational Institute on Aging2024 to 2025$5,825,826September 30, 2024July 31, 2029JOHNSON, ERIK C.B.reporter.nih.gov
Examining Effects of Intensive BP Control on MCI/Dementia and Plasma Biomarker Trajectories by AD Pathology: Elucidating neuroprotective effects in the racially and ethnically diverse SPRINT trialNIHNational Institute on Aging2025$5,789,766September 30, 2025June 30, 2030BRESS, ADAM Preporter.nih.gov
VCID and Stroke in a Bi-racial National CohortNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$5,761,773September 24, 2001September 16, 2024JUDD, SUZANNE Ereporter.nih.gov
First-in-Human (Phase 1) Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of IBC-Ab002 in Persons with Early Alzheimer's Disease (AD)NIHNational Institute on Aging2021 to 2023$5,749,685September 1, 2021August 31, 2024YOLES, ETIreporter.nih.gov
Genetic models of sporadic Alzheimers Disease in the marmosetNIHNational Institute on Aging2021 to 2024$5,749,378September 1, 2021June 30, 2026LEE, KUO-FENreporter.nih.gov
The Alzheimer Disease Sequence Analysis CollaborativeNIHNational Institute on Aging2021 to 2022$5,746,500September 30, 2018August 31, 2025HAINES, JONATHAN Lreporter.nih.gov
Discovery of Drugs that Modulate Neuroinflammation for the treatment of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2024$5,740,022June 15, 2021May 31, 2026HODGETTS, KEVINreporter.nih.gov
Cerebral tau deposition and comorbid cerebrovascular disease across the Alzheimer's disease continuum in Mexican AmericansNIHNational Institute on Aging2024 to 2025$5,730,361August 15, 2024August 31, 2029HABES, MOHAMADreporter.nih.gov
NPTX2: Preserving memory circuits in normative aging and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$5,697,103May 1, 2021April 30, 2027BARNES, CAROL A.reporter.nih.gov
Brain pathologies, reserve and cognition in aging and dementiaNIHNational Institute on Aging2022 to 2025$5,694,414March 1, 2009March 31, 2027TOMASZEWSKI-FARIAS, SARAH Ereporter.nih.gov
A Single Ascending Dose / Multiple Ascending Dose Phase I study of the GSM 776890 in healthy normal subjectsNIHNational Institute on Aging2021 to 2022$5,678,762February 1, 2021May 31, 2024GALASKO, DOUGLAS Rreporter.nih.gov
NBER Center for Aging and Health ResearchNIHNational Institute on Aging2021 to 2025$5,663,258August 1, 1997August 31, 2027CUTLER, DAVID Mreporter.nih.gov
Earlier-Life Predictors of Midlife Risk Factors for Dementia: A 35-Year Follow-up (Revision)NIHNational Institute on Aging2023 to 2025$5,646,724March 1, 2023February 29, 2028REBOK, GEORGE W.reporter.nih.gov
Identifying resilience proteins in key motor tissues that drive motor and cognitive decline and offset the negative effects of ADRD pathologies within and outside the brainNIHNational Institute on Aging2022 to 2025$5,619,647April 1, 2022January 31, 2027BUCHMAN, ARON Sreporter.nih.gov
Adversity, Aging and ADRD Risk among the Global Poor: A Biosocial Lifecourse ApproachNIHNational Institute on Aging2023 to 2025$5,604,169May 1, 2023February 28, 2029KOHLER, HANS-PETERreporter.nih.gov
Development of an Innovative Vervet (Chlorocebus aethiops sabaeus) Model of Early Alzheimer's-like Neuropathology and SymptomatologyNIHNational Institute on Aging2021 to 2024$5,592,774September 15, 2021May 31, 2026SHIVELY, CAROL A.reporter.nih.gov
Influence of Dietary Botanical Supplements on Biological and Behavioral ResilienceNIHNational Center for Complementary & Integrative Health2021 to 2024$5,585,106July 1, 2020June 30, 2026MURROUGH, JAMES WARRENreporter.nih.gov
Atlas for neuronal and glial cell types selectively vulnerable to proteinopathies during progression of Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$5,580,121June 1, 2023February 28, 2029LEE, KUO-FENreporter.nih.gov
Early risk factors of accelerated neural aging trajectories and cognitive decline: a nonhuman primate longitudinal modelNIHNational Institute on Aging2021 to 2025$5,565,416August 1, 2021April 30, 2027SANCHEZ, MAR Mreporter.nih.gov
Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study of India (LASI)-Genomic studyNIHNational Institute on Aging2021 to 2023$5,561,015September 15, 2019August 31, 2025LEE, JINKOOKreporter.nih.gov
Interplay of Myocardial Fibrosis and Cardiac TTR Amyloid in Age Related Cardiac Remodeling in MESA-Multi-Ethnic Study of AtherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,552,808April 1, 2022March 31, 2027LIMA, JOAO A Creporter.nih.gov
Roles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyNIHNational Institute on Aging2021$5,546,075March 1, 2005February 29, 2024AIZENSTEIN, HOWARD Jreporter.nih.gov
Alzheimer’s Disease Related Biomarkers following SARS-CoV-2 InfectionNIHNational Institute on Aging2022 to 2025$5,518,240June 15, 2022March 31, 2027WISNIEWSKI, THOMAS Mreporter.nih.gov
Phase II clinical trial of transcranial direct current stimulation in the treatment of primary progressive aphasiaNIHNational Institute on Aging2022 to 2025$5,516,416September 30, 2022May 31, 2027HAMILTON, ROY Hreporter.nih.gov
Primary Care Detection of Cognitive Impairment Leveraging Health and Consumer Technologies in Underserved Communities: The MyCog TrialNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$5,515,593September 25, 2017August 31, 2027WOLF, MICHAEL Sreporter.nih.gov
Enabling nationwide AD PET imaging to support most efficient clinical trials by adoption of radically simplified and standardized quality control in commercial production of AD PET tracers.NIHNational Institute on Aging2021 to 2025$5,508,448February 1, 2021April 30, 2027ELIZAROV, ARKADIJreporter.nih.gov
Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural PopulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,484,212March 6, 2020March 21, 2025GALVIN, JAMES Ereporter.nih.gov
Alzheimer Diagnosis in older Adults with Chronic Conditions ADACC NetworkNIHNational Institute on Aging2023 to 2025$5,472,632September 15, 2023May 31, 2028MIELKE, MICHELLE Mreporter.nih.gov
An automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populationsNIHNational Institute on Aging2023 to 2025$5,455,529August 15, 2023June 30, 2028GORNO TEMPINI, MARIA LUISAreporter.nih.gov
The role of 24-hour activity cycles in preserving cognitive function and preventing Alzheimer's disease and related dementiasNIHNational Institute on Aging2022$5,450,271June 1, 2022May 31, 2025DIAZ, KEITH Mreporter.nih.gov
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2025$5,445,522September 30, 2021May 31, 2027KELLIS, MANOLISreporter.nih.gov
Center for Label-free Imaging and Multiscale Biophotonics (CLIMB)NIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$5,439,409September 30, 2022June 20, 2027BOPPART, STEPHEN Areporter.nih.gov
Characterizing TDP-43 related hippocampal degeneration and memory loss in agingNIHNational Institute on Aging2021 to 2024$5,432,993June 1, 2020March 31, 2026SCHNEIDER, JULIE A.reporter.nih.gov
THE NNTC COLLECTS, STORE, AND PROVIDE CLINICAL DATA AND WELL CHARACTERIZED BIOLOGICAL SPECIMENS, INCLUDING POST-MORTEM TISSUE FROM STUDY VOLUNTEERS AND/OR ORGAN DONORS WITH HIV AS WELL AS HIV-NEGATIVENIHNational Institute of Mental Health2023 to 2025$5,429,596August 23, 2025August 22, 2026MOORE, DAVID Jreporter.nih.gov
Translational Control in Memory and Brain DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,426,946May 1, 2021April 30, 2029KLANN, ERICreporter.nih.gov
Vascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathologyNIHNational Institute of Neurological Disorders and Stroke2024$5,423,836September 19, 2024August 31, 2027YANG, ANDREW CHRISreporter.nih.gov
Identification of cognitive decline and dementia: Prediction by everyday driving behaviors and physiological responsesNIHNational Institute on Aging2021 to 2024$5,415,921September 15, 2020May 31, 2026GIORDANI, BRUNOreporter.nih.gov
Naturalistic driving as a functional neurobehavioral marker of preclinical and symptomatic Alzheimer diseaseNIHNational Institute on Aging2021 to 2024$5,397,726September 15, 2020May 31, 2026BABULAL, GANESH Mreporter.nih.gov
Leadership in AD/ADRD Drug DiscoveryNIHNational Institute on Aging2021 to 2025$5,389,748September 1, 2021August 31, 2027LIPTON, STUART Areporter.nih.gov
Multi-morbidity 3-City Alzheimer's Disease EHR Study (M3AD Study)NIHNational Institute on Aging2024$5,387,161September 17, 2024August 31, 2025DESVARIEUX, MOISEreporter.nih.gov
Clinical, Imaging, and Pathological Studies in the Oldest Old: The 90+ Study - RevisionNIHNational Institute on Aging2021 to 2024$5,354,279September 15, 2002May 31, 2025KAWAS, CLAUDIA H.reporter.nih.gov
Investigating the Benefits of Remotely-supervised Neuromodulation in Primary Progressive AphasiaNIHNational Institute on Aging2025$5,343,452September 15, 2025August 31, 2029HENRY, MAYAreporter.nih.gov
FDA approved IND 29644: Multicenter Phase 1 Trial to Evaluate Safety and Immunogenicity of Preventive Tau Vaccine, AV-1980R/A, in cognitively unimpaired preclinical AD participants.NIHNational Institute on Aging2025$5,308,961August 1, 2025July 31, 2030AGADJANYAN, MICHAEL Greporter.nih.gov
Phase 1 Clinical Trial of CMS121, a Novel Therapeutic Candidate for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$5,303,779September 15, 2021August 31, 2023RASCHKE, WILLIAM Creporter.nih.gov
Validation of Video Administration of a Modified UDSv3 Cognitive BatteryNIHNational Institute on Aging2022 to 2025$5,299,547March 1, 2022February 28, 2027SACHS, BONNIEreporter.nih.gov
Clinical Features and Neuropathological Basis of Sleep Wake Behavior in Alzheimer's and PSPNIHNational Institute on Aging2021 to 2025$5,284,458June 1, 2019March 31, 2029NEYLAN, THOMAS Creporter.nih.gov
Advancing Diagnosis of Dementia in Primary Care Practice(ADDPCP)NIHNational Institute on Aging2024 to 2025$5,273,754September 1, 2024May 31, 2029ROSEN, HOWARD Jreporter.nih.gov
Astrocyte and neuron brain-region and compartment-specific proteome dynamics in aging and Alzheimer’s diseaseNIHNational Institute on Aging2021 to 2025$5,247,255September 30, 2021July 31, 2026KHAKH, BALJITreporter.nih.gov
Advancing RNA Therapeutics for Huntington’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$5,226,511February 1, 2020January 31, 2026ARONIN, NEILreporter.nih.gov
Vervet Research Colony as a Biomedical ResourceNIHOffice of the Director, National Institutes of Health2021 to 2025$5,196,934July 1, 2004March 31, 2030JORGENSEN, MATTHEWreporter.nih.gov
Tau based Monkey model of Alzheimer's Disease; Structure and FunctionNIHNational Institute on Aging2021 to 2024$5,183,524September 1, 2021May 31, 2026MORRISON, JOHN Hreporter.nih.gov
Digital Health Technologies for Monitoring Motor Function in Progressive Supranuclear Palsy and Dementia with Lewy BodiesNIHNational Institute on Aging2025$5,174,076September 1, 2025August 31, 2029VAZIRI, ASHKANreporter.nih.gov
Mexican Teachers Cohort Study: Genetics and Cognitive FunctionNIHNational Institute on Aging2024 to 2025$5,167,040September 30, 2024August 31, 2029GRODSTEIN, FRANCINEreporter.nih.gov
Environmental Exposures and Brain HealthNIHNational Institute on Aging2025$5,164,012September 1, 2025August 31, 2029JAMES, PETERreporter.nih.gov
Characterizing the AD Metabolome in Brain Tissue Samples of Individuals from Diverse PopulationsNIHNational Institute on Aging2021 to 2022$5,150,658September 30, 2018August 31, 2025KADDURAH-DAOUK, RIMA Freporter.nih.gov
Using a Health Disparity Research Framework to examine mechanisms linking Obstructive Sleep Apnea with higher Alzheimer’s disease risk in older Blacks/African-AmericansNIHNational Institute on Aging2023 to 2025$5,141,003June 1, 2023April 30, 2028BUBU, OMONIGHO A MICHAELreporter.nih.gov
Microbial Impact on NeuroDegeneration in Alzheimer's Dementia: MIND-ADNIHNational Institute on Aging2021 to 2025$5,121,493September 30, 2021May 31, 2027SPIRA, ADAM PETERreporter.nih.gov
Developing the Privately Owned Companion Dog as a Model for Alzheimers DiseaseNIHNational Institute on Aging2021 to 2024$5,115,565September 1, 2021May 31, 2025KEENE, CHRISTOPHER DIRKreporter.nih.gov
The Neuropathologic Landscape of Alzheimer's Disease in Hispanic DecedentsNIHNational Institute on Aging2021 to 2025$5,113,642August 1, 2019July 31, 2029DUGGER, BRITTANY NICOLEreporter.nih.gov
Targeting Dysregulated RNA Splicing in Neurodegenerative DiseasesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$5,093,143September 1, 2023August 31, 2028LAGIER-TOURENNE, CLOTILDEreporter.nih.gov
Non-Invasive Home Neurostimulation for Mild to Moderate Alzheimer's Disease: Double-Blind, Sham Controlled Randomized Clinical TrialNIHNational Institute on Aging2021 to 2024$5,087,598September 15, 2020May 31, 2025VERGHESE, JOEreporter.nih.gov
A Precision Medicine Approach for the Study of Targetable Pathways in Vascular DementiaNIHNational Institute on Aging2022 to 2025$5,086,657February 1, 2022November 30, 2026GOATE, ALISON Mreporter.nih.gov
ARMCADA - Advancing Reliable Measurement in Cognitive Aging and Decision-making AbilityNIHNational Institute on Aging2023 to 2025$5,076,835April 1, 2023March 31, 2028GERSHON, RICHARDreporter.nih.gov
Enhancing Sleep Quality for Nursing Home Residents with Dementia: Pragmatic TrialNIHNational Institute on Aging2023 to 2025$5,065,841September 15, 2019April 30, 2027SNOW, A LYNNreporter.nih.gov
Dietary Restriction, GH/IGF-1 & Mechanisms of Cellular Protection and RegenerationNIHNational Institute on Aging2021 to 2023$5,057,227February 15, 2018January 31, 2024LONGO, VALTER D.reporter.nih.gov
Study of Latinos Investigation of Neurocognitive Aging 2NIHNational Institute on Aging2021$5,055,467September 1, 2015April 30, 2023GONZALEZ, HECTOR Mreporter.nih.gov
AI + Aging (a2) Coordinating Center for the NIA Artificial Intelligence and Technology Collaboratories for Aging Research (AITCs)NIHNational Institute on Aging2021 to 2025$5,055,437September 30, 2021May 31, 2027LI, ROSE MARIAreporter.nih.gov
Brain Health and Ethnic Disparities in ADRD Risk: The Case of Arab AmericansNIHNational Institute on Aging2021 to 2025$5,040,162April 1, 2021March 31, 2027ANTONUCCI, TONI CLAUDETTEreporter.nih.gov
Cardiorenal and Metabolic Diseases Research CenterNIHNational Institute of General Medical Sciences2021 to 2022$5,037,364September 5, 2013April 30, 2023HALL, JOHN Ereporter.nih.gov
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care SettingsNIHNational Institute on Aging2021 to 2025$5,006,816September 30, 2020May 31, 2026NOWINSKI, CINDY J.reporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2022$5,005,696September 1, 2022August 31, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Pragmatic Trial of the Effectiveness and Cost-Effectiveness of Dementia CareNIHNational Institute on Aging2021 to 2023$4,994,799September 30, 2018May 31, 2025REUBEN, DAVID B.reporter.nih.gov
USC-Yale Roybal Center for Behavioral Interventions in AgingNIHNational Institute on Aging2021 to 2025$4,993,847September 30, 2004May 31, 2029DOCTOR, JASON N.reporter.nih.gov
Multi-scale and multi-modality imaging of neuropathology in VCIDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,964,481September 22, 2023August 31, 2028GE, YULINreporter.nih.gov
IND Enabling Studies for RASRx 1902, a novel Mas receptor agonist, for treatment of cognitive impairment in patients at risk for Alzheimer's disease.NIHNational Institute on Aging2021 to 2023$4,958,940May 1, 2020April 30, 2026RODGERS, KATHLEEN E.reporter.nih.gov
Preventing Cognitive Decline by Reducing BP Target Trial (PCOT)NIHNational Institute on Aging2021 to 2024$4,956,317September 1, 2020August 31, 2025VAZQUEZ, MIGUEL Areporter.nih.gov
Novel Protein Biomarkers of Corticolimbic Pathophysiology in Lewy body DementiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$4,943,234September 15, 2022June 30, 2027SEYFRIED, NICHOLAS THOMASreporter.nih.gov
Botanicals enhancing neurological and functional resilience in aging (BENFRA)NIHNational Center for Complementary & Integrative Health2021 to 2024$4,931,479July 1, 2020June 30, 2026SOUMYANATH, AMALAreporter.nih.gov
Contribution of Longitudinal Neighborhood Determinants to Cognitive Health and Dementia Disparities within a Multi-Ethnic CohortNIHNational Institute on Aging2021 to 2025$4,930,675May 15, 2021February 28, 2027HIRSCH, JANA ARIELreporter.nih.gov
Assessing Novel Biomarkers for Cognitive Fluctuations in DLBNIHNational Institute of Neurological Disorders and Stroke2025$4,924,374September 1, 2025July 31, 2029PILLAI, JAGAN AYYAPPANreporter.nih.gov
Preclinical and early clinical development of a GABA-A a5 PAMNIHNational Institute on Aging2022 to 2025$4,921,400September 1, 2022August 31, 2026PAYIE, KENNETH Greporter.nih.gov
Establishing Sleep Apnea as a non-cognitive phenotype of brainstem ADRD pathologies in older adultsNIHNational Institute on Aging2021 to 2025$4,900,406April 1, 2021March 31, 2027VANDERHORST, VERONIQUEreporter.nih.gov
Molecular Diversity Among Hippocampal and Entorhinal Cells in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2021$4,896,138September 30, 2021August 31, 2024SESTAN, NENADreporter.nih.gov
Health of the Cholinergic System and Risk for Alzheimer's Disease in Postmenopausal WomenNIHNational Institute on Aging2021 to 2023$4,889,665September 15, 2019May 31, 2026DUMAS, JULIE Areporter.nih.gov
Federated digital pathology platform for AD/ADRD research and diagnosticsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,861,895September 20, 2023August 31, 2028NELSON, PETER T.reporter.nih.gov
Investigations of the protein aggregation inhibitor NU-9 and its derivatives: mode of action and impact on Alzheimer’s disease and related dementiasNIHNational Institute on Aging2021 to 2025$4,851,218August 1, 2019July 31, 2029OZDINLER, PEMBE HANDEreporter.nih.gov
CLINICAL RESEARCH OPERATIONS AND MANAGEMENT SYSTEM (CROMS) 2.0NIHNational Institute on Drug Abuse2025$4,851,124July 1, 2025June 30, 2026reporter.nih.gov
Upregulated Norepinephrine Synthesis Capacity in AgingNIHNational Institute on Aging2022 to 2025$4,846,427June 1, 2022March 31, 2027BERRY, ANNE SHIVELYreporter.nih.gov
China Health and Retirement Longitudinal studyNIHNational Institute on Aging2021 to 2024$4,842,807June 15, 2020February 28, 2025WANG, YAFENGreporter.nih.gov
Characterizing Cognitive Decline in Late Life Depression: The ADNI-D ProjectNIHNational Institute of Mental Health2022 to 2025$4,842,533August 1, 2013May 31, 2027MACKIN, ROBERT SCOTTreporter.nih.gov
Web-based Automated Imaging Differentiation of ParkinsonismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,837,150April 1, 2021March 31, 2027VAILLANCOURT, DAVID Ereporter.nih.gov
Reimagining Precision Medicine Approaches to AD DiagnosisNIHNational Institute on Aging2021 to 2025$4,816,964April 15, 2021March 31, 2027RABINOVICI, GIL DANreporter.nih.gov
[18F]-PU-AD epichaperome PET imaging probeNIHNational Institute on Aging2022 to 2025$4,816,476June 15, 2022May 31, 2027CHIOSIS, GABRIELAreporter.nih.gov
Vasculo-neuronal pathophysiological interface in Alzheimer’s and AtherosclerosisNIHNational Institute of Neurological Disorders and Stroke2024$4,815,513September 18, 2024August 31, 2027IRUELA-ARISPE, M. LUISAreporter.nih.gov
Hippocampal-dependent memory decline in aging and early Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$4,814,781February 1, 2022January 31, 2027MORMINO, ELIZABETHreporter.nih.gov
Achieving specificity in imaging neurodegeneration with visible light Optical Coherence TomographyNIHOffice of the Director, National Institutes of Health2024 to 2025$4,798,178September 15, 2024September 14, 2027SRINIVASAN, VIVEK JAYreporter.nih.gov
Cognitive Resilience among Older SamoansNIHNational Institute on Aging2021 to 2025$4,777,899March 1, 2021February 28, 2027LEVY, BECCA Rreporter.nih.gov
Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal ModelsNIHNational Institute on Aging2021 to 2024$4,771,429September 1, 2021May 31, 2025XU, XIANGMINreporter.nih.gov
The Role of Chemical Exposures in Alzheimer's Disease (AD) and its TrajectoryNIHNational Institute on Aging2024 to 2025$4,768,289August 15, 2024July 31, 2029KADDURAH-DAOUK, RIMA Freporter.nih.gov
Spatial navigation, sex hormones, and the aging brainNIHNational Institute on Aging2025$4,765,698August 5, 2025July 31, 2029JACOBS, EMILY Greporter.nih.gov
Preclinical development of a novel small molecule inhibitor of Alzheimer's disease-related cognitive impairmentNIHNational Institute on Aging2021 to 2023$4,763,535May 15, 2020April 30, 2025WATTERSON, DANIEL MARTINreporter.nih.gov
Training in the Molecular Biology of Neurodegeneration and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$4,742,300September 30, 1992August 31, 2027YANKNER, BRUCE Areporter.nih.gov
Novel retinal higher-order capillary hemodynamics imaging for detecting cerebral small vessel diseaseNIHOffice of the Director, National Institutes of Health2024 to 2025$4,719,171September 15, 2024September 14, 2027WANG, JIANHUAreporter.nih.gov
Center for Molecular Imaging Technology & Translation (CMITT)NIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$4,717,243September 30, 2017April 30, 2027EL FAKHRI, GEORGESreporter.nih.gov
Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$4,709,163May 15, 2014August 31, 2023ZHANG, BINreporter.nih.gov
Primary Progressive Aphasia: Cognition, Anatomy and ProgressionNIHNational Institute of Neurological Disorders and Stroke2022$4,705,247July 15, 2004August 31, 2025GORNO TEMPINI, MARIA LUISAreporter.nih.gov
The BrainCellQTL consortium: QTL mapping in the human brain at the single cell levelNIHNational Institute on Aging2024 to 2025$4,701,117April 15, 2024March 31, 2029ROUSSOS, PANAGIOTISreporter.nih.gov
Center to Accelerate Population Research in Alzheimer's (CAPRA)NIHNational Institute on Aging2021 to 2025$4,693,477August 1, 2020August 31, 2027BYNUM, JULIE PWreporter.nih.gov
Defining the molecular spectrum of white matter vascular lesionsNIHNational Institute of Neurological Disorders and Stroke2024$4,693,249September 17, 2024August 31, 2027HINMAN, JASON Dreporter.nih.gov
Brain mitochondrial PET imaging and 31P-MR spectroscopy to dissect the role of mitochondrial dysfunction in bioenergetic dysregulation in Dementia with Lewy Bodies pathogenesisNIHNational Institute on Aging2023 to 2025$4,683,243September 15, 2023May 31, 2029BERMAN, SARAH Breporter.nih.gov
Learning the Regulatory Code of Alzheimer's Disease GenomesNIHNational Institute on Aging2021 to 2024$4,650,607September 1, 2020August 31, 2025RAJ, TOWFIQUEreporter.nih.gov
Whole Genome Sequencing in Ethnically Diverse Cohorts for the ADSP Follow-Up Study (FUS)NIHNational Institute on Aging2021$4,626,374September 30, 2017August 31, 2024PERICAK-VANCE, MARGARET A.reporter.nih.gov
Towards Treatment of Alzheimer’s Disease by Targeting Pathogenic Tau and Beta-Amyloid StructuresNIHNational Institute on Aging2022 to 2025$4,622,158February 1, 2022January 31, 2027EISENBERG, DAVIDreporter.nih.gov
Sexual dimorphic cell type and connectivity atlases of the aging and AD mouse brainsNIHNational Institute on Aging2023 to 2025$4,621,936September 1, 2023May 31, 2028DONG, HONG-WEIreporter.nih.gov
Brain fluid clearance and misfolded protein dynamics following traumatic brain injuryNIHNational Institute on Aging2023 to 2025$4,618,282September 30, 2023June 30, 2029BUTLER, TRACY A.reporter.nih.gov
Aging of Emotion Circuitry and Risk for Alzheimer's disease: Impact of Sex, Immunity, and Fetal OriginsNIHNational Institute on Aging2021 to 2025$4,614,422June 15, 2018February 28, 2029GOLDSTEIN, JILL Mreporter.nih.gov
Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk FactorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,613,790December 15, 2015November 30, 2023STERN, ROBERT Areporter.nih.gov
Early Age-Related Hearing Loss Investigation (EARHLI): A Randomized Controlled Trial to Assess Mechanisms Linking Early Age-Related Hearing Loss and Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2022 to 2025$4,610,876September 15, 2022August 31, 2027GOLUB, JUSTIN SCOTTreporter.nih.gov
Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2)NIHNational Institute on Aging2021 to 2022$4,599,025June 1, 2015May 31, 2023REYNOLDS, CHANDRA Areporter.nih.gov
Model-based cerebrovascular markers extracted from hemodynamic data for diagnosing MCI or AD and predicting disease progression.NIHNational Institute on Aging2021 to 2022$4,594,525September 1, 2018May 31, 2025MARMARELIS, VASILIS Zreporter.nih.gov
Digital speech markers for early detection of Alzheimer’s disease in a longitudinal racially and ethnically diverse cohortNIHNational Institute on Aging2025$4,591,694September 5, 2025August 31, 2029VONK, JET M.J.reporter.nih.gov
Illuminating the APOE Locus with Long-Read Sequencing and Targeted GenomicsNIHNational Institute on Aging2021 to 2025$4,590,209September 1, 2021May 31, 2026GREICIUS, MICHAEL Dreporter.nih.gov
Cell Type-Specific Proteins that Promote Resilience to Cognitive Aging and Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$4,581,949September 30, 2021May 31, 2027KACZOROWSKI, CATHERINE COOKreporter.nih.gov
Therapeutic target discovery in ADSP data via comprehensive whole-genome analysis incorporating ethnic diversity and systems approachesNIHNational Institute on Aging2021 to 2022$4,574,416September 30, 2018August 31, 2025DESTEFANO, ANITA Lreporter.nih.gov
First in Human Study of a Tau Self-Association Small Molecule Inhibitor in Healthy VolunteersNIHNational Institute on Aging2022 to 2024$4,567,070August 1, 2022July 31, 2025ERHARDT, WILLIAM A.reporter.nih.gov
Development of a MT-stabilizing agent for the treatment of tauopathiesNIHNational Institute on Aging2024 to 2025$4,559,463September 1, 2024August 31, 2027CAFFREY, CONORreporter.nih.gov
USC/UCLA Center on Biodemography and Population HealthNIHNational Institute on Aging2021 to 2025$4,559,155August 15, 1999August 31, 2027CRIMMINS, EILEEN Mreporter.nih.gov
The wandering nerve: gateway to boost Alzheimer's disease related cognitive performanceNIHNational Institute on Aging2021 to 2025$4,558,716May 1, 2021April 30, 2027JACOBS, HEIDI IRMAreporter.nih.gov
The CHARMED model: a multimorbidity simulation model for people aging with HIVNIHNational Institute on Aging2021 to 2025$4,557,763April 1, 2021March 31, 2027HYLE, EMILY PARKERreporter.nih.gov
ACTIVE MIND: An adaptive clinical trial of cognitive training to improve function and delay dementiaNIHNational Institute on Aging2024$4,555,241September 1, 2024August 31, 2027EDWARDS, JERRIreporter.nih.gov
Sex-specific risk factors and trajectories of blood biomarkers for Alzheimer's disease and related dementiasNIHNational Institute on Aging2022 to 2024$4,547,001September 15, 2022August 31, 2025MURRAY, ANNE Mreporter.nih.gov
Completion of Non-clinical long-term GLP safety and GMP manufacture for first-in-class neuron regenerative therapy, NNI-362 Phase 2 POC AD trialNIHNational Institute on Aging2023 to 2024$4,543,556September 1, 2023August 31, 2025KELLEHER-ANDERSSON, JUDITH Areporter.nih.gov
An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCIDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,539,313September 22, 2023August 31, 2028VAN DER KOUWE, ANDRE JAN WILLEMreporter.nih.gov
Joint Estimate Diffusion Imaging (JEDI) for improved Tissue Characterization and Neural Connectivity in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$4,533,578June 1, 2023February 29, 2028FRANK, LAWRENCE Rreporter.nih.gov
Shared resource to develop tools and reagents to study structural polymorphisms in Abeta amyloid aggregates in ADNIHNational Institute on Aging2022 to 2025$4,533,350September 30, 2022May 31, 2027GLABE, CHARLES G.reporter.nih.gov
Center on the Economics and Demography of AgingNIHNational Institute on Aging2021 to 2025$4,524,890July 1, 1997August 31, 2027DOW, WILLIAM Hreporter.nih.gov
Supplemental Request: Therapeutic APOE2 overexpression for early Alzheimer's diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,517,405May 1, 2019April 30, 2023DAVIDSON, BEVERLY L.reporter.nih.gov
IMPACT-ADRD: Investigating the Multi-omics Perturbations Associated with Complex Environmental Toxicants and their Contribution to Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2024 to 2025$4,511,944August 15, 2024July 31, 2029HUELS, ANKEreporter.nih.gov
Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,511,697January 1, 2019December 31, 2026NELSON, MARK Treporter.nih.gov
Targeting REST in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$4,505,937May 1, 2021April 30, 2027YANKNER, BRUCE Areporter.nih.gov
African Ancestry and the Genomic Architecture of AD and Other Common Neurodegenerative Disease NeuropathologiesNIHNational Institute on Aging2021 to 2023$4,504,699September 15, 2016May 31, 2024BENNETT, DAVID ALANreporter.nih.gov
Spousal dementia caregivers: Risk for accelerated agingNIHNational Institute on Aging2021 to 2024$4,503,425September 15, 2020May 31, 2026CHRISTIAN, LISA MICHELLEreporter.nih.gov
A Phase 1b Multiple Ascending Dose Study of the Safety and Tolerability of BMS-984923 in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$4,500,015September 30, 2021August 31, 2025MECCA, ADAM PETERreporter.nih.gov
A Pragmatic Crossover Trial to Test the Effectiveness of a Novel Lighting System to Reduce Nighttime Falls in Persons with Alzheimer’s Disease and Related DementiasNIHNational Institute on Aging2022 to 2025$4,499,469July 1, 2022June 30, 2028ZIMMERMAN, SHERYLreporter.nih.gov
Ambulatory Methods for Measuring Cognitive ChangeNIHNational Institute on Aging2021 to 2022$4,488,274September 15, 2018May 31, 2025SLIWINSKI, MARTIN Jreporter.nih.gov
Development and Validation of a Marmoset Model of Late-Onset Alzheimer Disease Based on Tau SeedingNIHNational Institute on Aging2021 to 2024$4,484,803August 15, 2021May 31, 2025SILVA, AFONSO Creporter.nih.gov
Prognostic Implications of Home-Based Blood Pressure Monitoring in Older AdultsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,461,092July 20, 2021May 31, 2027JURASCHEK, STEPHEN Preporter.nih.gov
Innovative Deep Phenotyping of African Americans at Risk for Alzheimers diseaseNIHNational Institute on Aging2023 to 2025$4,456,098June 1, 2023February 29, 2028LOEWENSTEIN, DAVIDreporter.nih.gov
Harnessing Diverse Bioinformatic Approaches To Repurpose Drugs For Alzheimers Disease And Related DementiasNIHNational Institute on Aging2021 to 2025$4,452,998September 30, 2018May 31, 2028ALBERS, MARK Wreporter.nih.gov
A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC CollaborationNIHNational Institute on Aging2023 to 2025$4,445,528September 15, 2017June 30, 2028SACHDEV, PERMINDER Sreporter.nih.gov
A Phase 3 Pivotal Trial of AGB101 to Slow Progression in MCI due to Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$4,440,050September 30, 2018May 31, 2025MOHS, RICHARD CHARLESreporter.nih.gov
Cognitive Computing of Alzheimer's Disease Genes and RiskNIHNational Institute on Aging2021 to 2025$4,431,314July 1, 2021June 30, 2027LICHTARGE, OLIVIERreporter.nih.gov
Combining Computational Methods, RDoC, and Big Neuroimaging Data to Understand Mechanisms of Neuropsychiatric Symptoms in Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$4,421,675September 30, 2022August 31, 2027NICKERSON, LISA Dreporter.nih.gov
Measurement and Analysis of Aging, Cognition and Alzheimer's Disease and Related Dementia (ADRD) Risk Factors at Midlife in the Kenya Life Panel Survey (KLPS)NIHNational Institute on Aging2022 to 2025$4,411,923May 15, 2022April 30, 2027MIGUEL, EDWARD ANDREWreporter.nih.gov
Project HoPe: Achieving Home Discharge for institutionally-bound Patients with PROMs, AI, and the EHRNIHNational Institute on Aging2022 to 2025$4,403,711August 3, 2022April 30, 2028CHEVILLE, ANDREA LYNNEreporter.nih.gov
Alzheimer's dementia onset and progression in international cohorts (Amended)NIHNational Institute on Aging2021 to 2022$4,403,042September 30, 2018May 31, 2025MASTERS, COLINreporter.nih.gov
Cognitive Impairment and Dementia, Vascular Brain Injury, and Atrial Myopathy: Implications for Prevention of Alzheimer's Disease-Related DementiasNIHNational Institute of Neurological Disorders and Stroke2023$4,390,219September 20, 2023August 31, 2026CHEN, LIN YEEreporter.nih.gov
Precursors of Stroke Incidence and PrognosisNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,368,194December 1, 1981August 31, 2028ROMERO, JOSE RAFAELreporter.nih.gov
5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical TrialNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$4,365,934September 15, 2017October 31, 2024VERGHESE, JOEreporter.nih.gov
Optimizing a closed-loop digital meditation intervention for remediating cognitive decline and reducing stress in older adultsNIHNational Institute on Aging2022 to 2024$4,364,410June 1, 2022May 31, 2027ZIEGLER, DAVID Areporter.nih.gov
COGNITIVE TRAINING AND NEUROPLASTICITY IN MILD COGNITIVE IMPAIRMENTNIHNational Institute on Aging2021 to 2025$4,364,339July 15, 2017February 28, 2029DEVANAND, DAVANGERE Preporter.nih.gov
VCID Center Without Walls for Understanding and Leveraging Small Vessel Cerebrovascular Disease Mechanisms in ADRDNIHNational Institute of Neurological Disorders and Stroke2024$4,361,625September 24, 2024August 31, 2027LEE, JIN-MOOreporter.nih.gov
Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,359,590December 1, 2016November 30, 2024GITLER, AARON D.reporter.nih.gov
Vanderbilt Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2023$4,356,837August 15, 2020July 31, 2025JEFFERSON, ANGELA L.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Southern CaliforniaLos Angeles, CA158$538.6 million0$0
Columbia University Health SciencesNew York, NY216$534.2 million0$0
Washington UniversitySaint Louis, MO193$509.8 million0$0
University of California, San FranciscoSan Francisco, CA267$487.5 million0$0
Johns Hopkins UniversityBaltimore, MD235$474.5 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA129$391.2 million0$0
Massachusetts General HospitalBoston, MA254$388.5 million0$0
University of PennsylvaniaPhiladelphia, PA173$353.7 million0$0
University of Michigan at Ann ArborAnn Arbor, MI148$349.3 million0$0
University of Wisconsin-MadisonMadison, WI112$339 million0$0
University of California, San DiegoLa Jolla, CA161$313.9 million0$0
Indiana University IndianapolisIndianapolis, IN102$304.5 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY148$297.1 million0$0
University of Miami School of MedicineCoral Gables, FL62$254.2 million0$0
Boston University Medical CampusBoston, MA111$236.4 million0$0
Emory UniversityAtlanta, GA130$227 million0$0
Northwestern University at ChicagoChicago, IL111$223.1 million0$0
Brigham and Women's HospitalBoston, MA95$215.5 million0$0
University of California-IrvineIrvine, CA112$215.4 million0$0
Mayo Clinic RochesterRochester, MN71$205.5 million0$0
Stanford UniversityStanford, CA137$184.7 million0$0
University of MinnesotaMinneapolis, MN94$170.6 million0$0
University of WashingtonSeattle, WA88$168.5 million0$0
Brown UniversityProvidence, RI71$165.3 million0$0
Yale UniversityNew Haven, CT111$160.9 million0$0
Rush University Medical CenterChicago, IL52$158.4 million0$0
New York University School of MedicineNew York, NY75$151.6 million0$0
Vanderbilt University Medical CenterNashville, TN58$150 million0$0
Duke UniversityDurham, NC79$149 million0$0
University of California at DavisDavis, CA68$148 million0$0
University of FloridaGainesville, FL123$145.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY96$139.7 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC91$134.9 million0$0
University of California Los AngelesLos Angeles, CA88$132.9 million0$0
Northern California Institute/res/eduSan Francisco, CA15$120.8 million0$0
Wake Forest University Health SciencesWinston-Salem, NC58$120.7 million0$0
University of ArizonaTucson, AZ47$112.6 million0$0
University of KentuckyLexington, KY82$112.4 million0$0
University of Alabama at BirminghamBirmingham, AL92$112.4 million0$0
Baylor College of MedicineHouston, TX71$111.6 million0$0
University of Colorado DenverAurora, CO67$105.2 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX77$99 million0$0
University of Texas HLTH Science CenterSan Antonio, TX49$97.3 million0$0
Mayo Clinic JacksonvilleJacksonville, FL46$95.5 million0$0
Banner HealthPhoenix, AZ10$91.7 million0$0
University of Kansas Medical CenterKansas City, KS47$89.8 million0$0
Cognition Therapeutics, Inc.Pittsburgh, PA5$86.6 million0$0
University of South FloridaTampa, FL47$86.1 million0$0
Ut Southwestern Medical CenterDallas, TX50$84.9 million0$0
University of Maryland BaltimoreBaltimore, MD56$81.8 million0$0
University of California-BerkeleyBerkeley, CA37$79 million0$0
University of Texas at AustinAustin, TX32$75.5 million0$0
Albert Einstein College of MedicineBronx, NY30$74 million0$0
Case Western Reserve UniversityCleveland, OH60$73.2 million0$0
J. David Gladstone InstitutesSan Francisco, CA33$72.6 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA53$71.8 million0$0
Massachusetts Institute of TechnologyCambridge, MA36$71.2 million0$0
Scripps Research Institute, theLa Jolla, CA37$66.5 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH40$66.3 million0$0
Tulane University of LouisianaNew Orleans, LA20$60.4 million0$0
Oregon Health & Science UniversityPortland, OR51$58.1 million0$0
California Pacific Med CTR Res InstituteSan Francisco, CA5$58.1 million0$0
Beth Israel Deaconess Medical CenterBoston, MA29$54.4 million0$0
University of Illinois at ChicagoChicago, IL51$54 million0$0
Allen InstituteSeattle, WA2$51.3 million0$0
Harvard Medical SchoolBoston, MA35$50.1 million0$0
University of North Texas HLTH Sci CTRFort Worth, TX10$49.2 million0$0
Ohio State UniversityColumbus, OH46$49.1 million0$0
University of RochesterRochester, NY49$48.8 million0$0
Vanderbilt UniversityNashville, TN46$48.6 million0$0
Augusta UniversityAugusta, GA29$47 million0$0
University of IowaIowa City, IA45$47 million0$0
Buck Institute for Research on AgingNovato, CA21$46.5 million0$0
Medical University of South CarolinaCharleston, SC32$45.9 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA23$44.7 million0$0
University of Texas Med BR GalvestonGalveston, TX31$44.4 million0$0
University of VirginiaCharlottesville, VA46$44.3 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA22$43.7 million0$0
SUNY at Stony BrookStony Brook, NY32$42.4 million0$0
Salk Institute for Biological StudiesLa Jolla, CA15$40.2 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA9$39.1 million0$0
University of UtahSalt Lake City, UT33$38.8 million0$0
Arizona State UniversityScottsdale, AZ29$38.7 million0$0
Alzheon, Inc.Framingham, MA1$36.2 million0$0
National Opinion Research CenterChicago, IL5$34.7 million0$0
University of CincinnatiCincinnati, OH16$33.8 million0$0
University of ChicagoChicago, IL19$33.6 million0$0
Georgetown UniversityWashington, DC29$32.8 million0$0
Winifred Masterson Burke Med Res InstWhite Plains, NY2$32.5 million0$0
Harvard UniversityCambridge, MA9$32 million0$0
University of DelawareNewark, DE12$31.8 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ32$30.6 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN4$30.3 million0$0
Mclean HospitalBelmont, MA8$29.8 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA18$29.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA23$29.4 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY11$29.3 million0$0
University of Vermont & ST Agric CollegeBurlington, VT14$29.1 million0$0
Jackson LaboratoryBar Harbor, ME20$28.9 million0$0
Seattle Inst for Biomedical/clinical ResSeattle, WA16$28.1 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20253,603$3,244,517,4940$0
20243,981$3,194,491,3280$0
20233,744$3,216,253,1600$0
20223,678$3,067,453,5650$0
20213,442$2,817,748,2670$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 50 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 5 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 4 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 4 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIHNovember 24, 2026Not listedNotice number printed on 2 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)PA-24-179NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32)PAR-25-250NIHJanuary 7, 2028Not listedNotice number printed on 1 award here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)PAR-25-095NIH93.866November 6, 2026$350,000Same assistance listing 93.866 as 6,470 awards here
Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)RFA-AG-27-010NIH93.866November 10, 2026Not listedSame assistance listing 93.866 as 6,470 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)PAR-25-096NIH93.866November 17, 2026$200,000Same assistance listing 93.866 as 6,470 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.866November 23, 2026$375,000Same assistance listing 93.866 as 6,470 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.866December 3, 2026Not listedSame assistance listing 93.866 as 6,470 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.866December 3, 2026Not listedSame assistance listing 93.866 as 6,470 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.866December 4, 2026Not listedSame assistance listing 93.866 as 6,470 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.866January 5, 2027Not listedSame assistance listing 93.866 as 6,470 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.866January 5, 2027Not listedSame assistance listing 93.866 as 6,470 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.