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Data / Research funding / Congenital Structural Anomalies

Congenital Structural Anomalies: 2,300 NIH awards ($2.4B) to 316 organizations

2,300 NIH awards ($2.4B) in the NIH spending category Congenital Structural Anomalies, to 316 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 2,300 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)NIHNational Institute of Dental & Craniofacial Research2021 to 2024$25,635,194May 7, 2020April 30, 2026CHAI, YANGreporter.nih.gov
Ola HAWAIINIHNational Institute on Minority Health and Health Disparities2021 to 2025$25,522,287September 23, 1997May 31, 2027HEDGES, JERRIS ROBERTreporter.nih.gov
EO14042 DEVELOPMENT, STATISTICAL DESIGN, MONITORING AND COORDINATION OF VISION CLINICAL TRIALS AND EPIDEMIOLOGY RESEARCHNIHOffice of the Director, National Institutes of Health2022 to 2025$25,277,032November 1, 2021October 31, 2026MENEZES, SUPRIYAreporter.nih.gov
Michigan-Pittsburgh-Wyss Regenerative Medicine Resource Center: Advancing Dental, Oral, and Craniofacial Regeneration to Clinical Trial InitiationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$24,937,885May 1, 2020April 30, 2026KOHN, DAVID H.reporter.nih.gov
Administrative Coordinating Center: Bench to Bassinet ProgramNIHNational Heart, Lung, and Blood Institute2021 to 2024$21,378,391January 1, 2016December 31, 2025OLLBERDING, NICHOLAS Jreporter.nih.gov
Childhood Liver Disease Research Network (ChiLDReN) Scientific and Data Coordinating CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,404,513September 18, 2002May 31, 2029MAGEE, JOHN Creporter.nih.gov
Multiscale functional characterization of genomic variation in human developmental disordersNIHNational Human Genome Research Institute2021 to 2025$8,736,987September 1, 2021May 31, 2027HON, GARY CHUNGreporter.nih.gov
Supplement Year 2: USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration HubNIHNational Institute of Dental & Craniofacial Research2021 to 2023$8,573,318August 1, 2019July 31, 2024KESSELMAN, CARLreporter.nih.gov
Utilization of Advanced Technologies for the Understanding of Human Structural Birth DefectsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$8,390,717January 11, 2021December 31, 2025BEIER, DAVID R.reporter.nih.gov
IGF::OT::IGFEMMES NEIS-VNIHOffice of the Director, National Institutes of Health2021$7,315,897November 1, 2016October 31, 2021HAMMEL, KERIreporter.nih.gov
Brittle Bone Disorders Consortium of the Rare Disease Clinical Research NetworkNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$6,852,525September 15, 2014August 31, 2030LEE, BRENDANreporter.nih.gov
Cavopulmonary Assist to Reverse the FontanNIHNational Heart, Lung, and Blood Institute2021 to 2023$6,543,627September 14, 2020August 31, 2025RODEFELD, MARK Dreporter.nih.gov
NIDCD Temporal Bone ResourceNIHNational Institute of Dental & Craniofacial Research2024 to 2025$6,423,500January 1, 2025May 31, 2029KESSELMAN, CARLreporter.nih.gov
Intellectual and Developmental Disabilities Research CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$6,255,512June 1, 2025May 31, 2026JUUL, SANDRA Ereporter.nih.gov
Cardiovascular Development Data Resource Center (CDDRC)NIHNational Heart, Lung, and Blood Institute2021 to 2024$5,768,733August 20, 2020July 31, 2025YOST, H. JOSEPHreporter.nih.gov
Mechanical Clocks During Fetal DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$5,658,660September 16, 2022August 31, 2027NELSON, CELESTE Mreporter.nih.gov
System Wide Operations for Rare Disorders (SWORD)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,227,397September 30, 2009June 30, 2025KIM, HELENreporter.nih.gov
A Shared Neuroscience Platform for National Dissemination and Training in Brain Organogenesis, Behavioral and Brain Disease Models, Viral Vectors, and Imaging TechnologiesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$5,191,106June 16, 2022May 31, 2027SHAMLOO, MEHRDADreporter.nih.gov
Trisomy 21 and its impact on hedgehog-dependent gene regulation and differentiation timingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$5,112,898September 1, 2024March 31, 2026MOSKOWITZ, IVAN PAULreporter.nih.gov
Planar cell polarity mechanisms and systems architectureNIHNational Institute of General Medical Sciences2021 to 2025$4,888,004September 16, 2019August 31, 2029AXELROD, JEFFREY D.reporter.nih.gov
Mechanisms underlying the multifaceted basis of craniofacial dysmorphogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,875,590September 1, 2019June 30, 2027EBERHART, JOHANN Kreporter.nih.gov
Targeted DOK7 gene therapy for Congenital Myasthenic SyndromesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,856,116September 15, 2021August 31, 2026SEPULVEDA, PATRICIOreporter.nih.gov
Central Coordinating Site for the Polycystic Kidney Disease (PKD) Research Core CentersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,824,202July 20, 2020August 31, 2030WATNICK, TERRY Jreporter.nih.gov
Maryland Polycystic Kidney Disease Research Core Center (MPKD-RCC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,654,991August 24, 2020August 31, 2030WATNICK, TERRY Jreporter.nih.gov
Toward efficient performance for deep learning on medical imagingNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,624,228April 1, 2020March 31, 2030ARNAOUT, RIMAreporter.nih.gov
Pathological Mechanisms of Human Cerebellar MalformationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,519,501September 1, 2016June 30, 2028MILLEN, KATHLEEN JOYCEreporter.nih.gov
U24-Uncovering the Shared Genetic Origins of Childhood Cancer and Structural Birth Defects Through Enhanced Data Integration and Analysis with the CFDE Data Distillery Knowledge Graph.NIHOffice of the Director, National Institutes of Health2024 to 2025$4,408,884September 19, 2024August 31, 2027TAYLOR, DEANNE MARIEreporter.nih.gov
Progenitor Regulation in Craniofacial Development and RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$4,376,497September 14, 2017June 30, 2026CRUMP, GAGE Dreporter.nih.gov
UAB Childhood Cystic Kidney Disease Center (UAB-CCKDC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,330,298July 20, 2020August 31, 2030YODER, BRADLEY K.reporter.nih.gov
Body Composition and Energy Expenditure in Youth with Spina BifidaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$4,224,862July 1, 2019November 30, 2025POLFUSS, MICHELEreporter.nih.gov
: Clinical Outcomes in Aicardi Goutières SyndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$4,216,994July 1, 2019June 30, 2025VANDERVER, ADELINE LUCIEreporter.nih.gov
Evaluating Assessment and Medication Treatment of ADHD in Children with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$4,182,561May 1, 2024August 31, 2025ESBENSEN, ANNA J.reporter.nih.gov
Signaling control and cellular basis of craniofacial morphogenesis and congenital diseaseNIHNational Institute of Dental & Craniofacial Research2022 to 2025$4,167,216April 1, 2022March 31, 2030BUSH, JEFFREY OHMANNreporter.nih.gov
NIH Osteoporosis and Related Bone Diseases~National Resource Center (NRC)NIHNational Heart, Lung, and Blood Institute2021 to 2022$4,052,641January 15, 2018January 14, 2023BOWEN, MATTreporter.nih.gov
Coronal Suture Development in Health and DiseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,959,879September 20, 2021July 31, 2027HOLMES, GREG PETERreporter.nih.gov
Pulmonary Valved Graft with Regeneration Potential for Pediatric PatientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,958,584May 24, 2019February 28, 2027HOUDE, AJAYreporter.nih.gov
Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,938,586March 15, 2021February 28, 2027GRANT, PATRICIA ELLENreporter.nih.gov
Targeting Mitochondria in Single Ventricle Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,873,722March 15, 2021January 31, 2026MIYAMOTO, SHELLEY DEANNEreporter.nih.gov
In vivo Pathway Discovery in Autosomal Dominant Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,867,356September 9, 2019June 30, 2025SOMLO, STEFANreporter.nih.gov
Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart DefectsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,824,765July 1, 2015February 28, 2027JENKINS, MICHAEL W.reporter.nih.gov
SCGE Disease Models Studies Supplement: Development of LNP-mediated based editing to treat Leber Congenital Amaurosis (LCA) for vision restoration in mouse modelNIHNational Center for Advancing Translational Sciences2021 to 2022$3,783,475September 18, 2018July 31, 2023CHEN, ZHENG-YIreporter.nih.gov
Studies on the structure of basement membranesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,732,265September 1, 1986June 30, 2029HUDSON, BILLY GERALDreporter.nih.gov
Cilia in Heart Development and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,728,670February 15, 2019January 31, 2026BRUECKNER, MARTINAreporter.nih.gov
Cardiogenesis: Molecular MechanismsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,717,603January 10, 1997May 31, 2028SRIVASTAVA, DEEPAKreporter.nih.gov
Gastroschisis Outcomes of Delivery (GOOD) StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,695,902April 13, 2021March 31, 2027WAGNER, AMY Jreporter.nih.gov
Harnessing the therapeutic potential of neural crest cells by manipulating the primary ciliumNIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,694,614September 14, 2017June 30, 2025BRUGMANN, SAMANTHA Areporter.nih.gov
Neurodevelopment after postnatal Zika virus infection in infant macaquesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,679,627January 1, 2021November 30, 2026CHAHROUDI, ANN Mreporter.nih.gov
Clinical Diagnostic Sequencing of Structural VariationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,579,081April 1, 2015August 31, 2026TALKOWSKI, MICHAEL Ereporter.nih.gov
Multiscale coordination of planar cell polarityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,552,205September 19, 2025August 31, 2028DEVENPORT, DANELLE Nreporter.nih.gov
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical TrialNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,521,212September 15, 2020August 31, 2025BERGER, STUARTreporter.nih.gov
Evaluation of Clinical Outcome Assessment (COA) and Potential Biomarkers to Facilitate Interventional Trial for Mucopolysaccharidosis IIID PatientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,519,934September 21, 2021August 31, 2025SINGAMSETTY, SRIKANTHreporter.nih.gov
Inductive and morphogenetic processes shaping the zebrafish embryonic axesNIHNational Institute of General Medical Sciences2021 to 2025$3,518,099May 1, 2016May 31, 2026SOLNICAKREZEL, LILIANNAreporter.nih.gov
Mosaic: post-zygotic mutations in vascular malformationsNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,511,307February 8, 2016June 30, 2025BENNETT, JAMES Treporter.nih.gov
Clinical Center for Cholestatic Liver Disease in ChildrenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,505,921September 15, 2002May 31, 2029MIETHKE, ALEXANDERreporter.nih.gov
Craniofacial Morphogenesis in Prenatal Alcohol ExposureNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,497,846July 1, 1996August 31, 2029SMITH, SUSAN M.reporter.nih.gov
Health and Psychosocial Outcomes in Young Children with Cleft PalateNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,452,399August 1, 2021July 31, 2027CRERAND, CANICE ELLENreporter.nih.gov
Viral Gene Therapy for Menkes DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,444,962September 1, 2023June 30, 2027KALER, STEPHEN GERARDreporter.nih.gov
Single-cell epigenomic phenotyping of IMPC-generated mouse lines lacking chromatin regulatorsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,429,432June 1, 2021May 31, 2026GORKIN, DAVID USCHERreporter.nih.gov
Regulation of TLR signaling, Inflammation and Antigen Presentation by VPS33BNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,409,595July 1, 2021June 30, 2026PASARE, CHANDRASHEKHARreporter.nih.gov
Velopharyngeal insufficiency following cleft palate repair: a comparative effectiveness study of existing surgical procedures and identification of criteria to guide a personalized treatment approachNIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,404,346July 1, 2020June 30, 2026SITZMAN, THOMAS JAMESreporter.nih.gov
Developmental origins and homeostatic mechanisms underlying adult phenotypesNIHNational Institute of General Medical Sciences2021 to 2025$3,384,344May 1, 2017April 30, 2027PARICHY, DAVID Mreporter.nih.gov
Cellular and molecular mechanisms underlying DDX3X syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,350,844January 1, 2021November 30, 2026SILVER, DEBRA L.reporter.nih.gov
Genetic Control of Cardiac Development: Congenital Heart Disease Gene Discovery in DrosophilaNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,338,929August 1, 1995June 30, 2025BODMER, ROLFreporter.nih.gov
Role of Energy Metabolism in Patterning the Vertebrate Musculo-Skeletal AxisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,337,554March 1, 2016March 31, 2026POURQUIE, OLIVIERreporter.nih.gov
Why do Down Syndrome patients have high risk of Hirschsprung disease?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,330,453September 15, 2022July 31, 2027CHAKRAVARTI, ARAVINDAreporter.nih.gov
Novel peptide-impregnated hydrogel as a wound healing deviceNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,317,905April 1, 2016August 31, 2025ZHENG, ZHONGreporter.nih.gov
Primary Cilia: A Novel Signaling Gateway To Neural Circuit ModulationNIHNational Institute of Mental Health2022 to 2024$3,316,034August 19, 2022May 31, 2027ANTON, EVA Sreporter.nih.gov
Progressive acquisition of novel neural crest derivatives along the neural axis during vertebrate evolutionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,298,565May 15, 2019April 30, 2027BRONNER, MARIANNEreporter.nih.gov
Development of a Polymeric Percutaneous Pulmonary Valve for Use in Young ChildrenNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,231,750August 15, 2016February 28, 2029HARRINGTON, DANIEL Areporter.nih.gov
Promoting Preconception Care and Diabetes Self-Management among Reproductive-Aged Women with Diabetes: The PREPARED TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,218,943August 6, 2021June 30, 2027BAILEY, STACY Creporter.nih.gov
Wnt/Frizzled-PCP signaling in development and diseaseNIHNational Institute of General Medical Sciences2021 to 2025$3,213,988May 1, 2018April 30, 2028MLODZIK, MAREKreporter.nih.gov
Microstructural Response of the Myocardium to Mechanical LoadNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,205,295July 1, 2021May 31, 2026SOSNOVIK, DAVID Ereporter.nih.gov
ACC: Callosal Agenesis as a Window into Common Neurodevelopmental DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,202,009March 1, 2008April 30, 2027ARGILLI, EMANUELAreporter.nih.gov
Molecular mechanisms underlying force transduction at cellular adhesion complexesNIHNational Institute of General Medical Sciences2021 to 2025$3,192,720May 6, 2019June 30, 2029DUNN, ALEXANDER Rreporter.nih.gov
Human Umbilical Cord as a Regenerative Meningeal Patch to Prevent Tethering and Improve Neurological Function Following In-Utero Spina Bifida RepairNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,190,303April 1, 2021February 28, 2027PAPANNA, RAMESHAreporter.nih.gov
Regulation of Growth and MorphogenesisNIHNational Institute of General Medical Sciences2021 to 2025$3,183,036May 1, 2019April 30, 2029IRVINE, KENNETH Dreporter.nih.gov
Prenatal Environment And Child Health (PEACH) in ECHONIHOffice of the Director, National Institutes of Health2023 to 2024$3,172,491September 1, 2023May 31, 2025SCHMIDT, REBECCA JEANreporter.nih.gov
Signaling Mechanisms of Lens DevelopmentNIHNational Eye Institute2021 to 2025$3,164,271January 1, 2006September 14, 2028ZHANG, XINreporter.nih.gov
DUCTUS ARTERIOSUS STENT TO IMPROVE CONGENITAL HEART DEFECT MORTALITYNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,158,101August 6, 2021December 31, 2027TANG, BEVERLYreporter.nih.gov
Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementiaNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,134,584January 1, 2018December 31, 2023NICHOLS, COLIN Greporter.nih.gov
Dissection of the Molecular Basis of Pleiotropy Between GnRH Neuronal Development and Cranial Suture FusionNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,120,836August 1, 2022May 31, 2027BALASUBRAMANIAN, RAVIKUMARreporter.nih.gov
Defective heme transport in the development of congenital hydrocephalusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,120,419September 1, 2021June 30, 2026ARNOLD, THOMAS DARMODYreporter.nih.gov
Pbx-Directed Control of Cellular Behaviors that Drive Midface MorphogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,117,485July 15, 2021May 31, 2027SELLERI, LICIAreporter.nih.gov
Predicting Tissue Specific Gli3 Regulatory Activity Using Hand2NIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,109,614June 16, 2022March 31, 2027PETERSON, KEVIN ANTHONYreporter.nih.gov
Delineating mechanisms underlying azole-induced developmental toxicity using single cell transcriptomic approaches, genome editing tools, and alternative modelsNIHNational Institute of Environmental Health Sciences2022 to 2025$3,107,691March 4, 2022December 31, 2026ROBINSON, JOSHUA FREDERICKreporter.nih.gov
Crosstalk Between Lipid Droplets and Other Organelles in PodocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,102,617September 5, 2025September 4, 2029FORNONI, ALESSIAreporter.nih.gov
ADPKD: Disease Spectrum & Genotype-Phenotype CorrelationsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,092,802August 1, 2001May 31, 2028HARRIS, PETER C.reporter.nih.gov
Refining the Genetic and Genomic Architecture of Non‐syndromic Orofacial CleftsNIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,084,954February 1, 2020January 31, 2026BUTALI, AZEEZreporter.nih.gov
Genetic modifiers of congenital heart disease in 22q11.2 deletion syndromeNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,070,980February 1, 2022January 31, 2027MORROW, BERNICE Ereporter.nih.gov
Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial cleftingNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,070,067January 1, 2022December 31, 2026BRAND, HARRISONreporter.nih.gov
Genetic determinants of 4D genome folding in human cardiac developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,069,960September 21, 2020August 31, 2025BRUNEAU, BENOIT GAETANreporter.nih.gov
Mechanobiology of Cardiac Outflow Tract MorphogenesisNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,068,575March 15, 2022February 28, 2027BUTCHER, JONATHAN TALBOTreporter.nih.gov
Metabolic profiling and comprehensive metabolic pathway mapping: a systems biology approach to cardiovascular failure and organ injury following infant congenital heart disease surgeryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,061,754May 1, 2021April 30, 2027DAVIDSON, JESSEreporter.nih.gov
Gene-by-environment interactions that affect exposure-mediated congenital heart diseaseNIHNational Institute of Environmental Health Sciences2021 to 2025$3,058,037September 10, 2021June 30, 2027WHITEHEAD, JOHN ANDREWreporter.nih.gov
Molecular and Cellular Basis of CraniosynostosisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,051,443July 1, 2016July 31, 2026CRUMP, GAGE Dreporter.nih.gov
Early neural predictors and neuropathogenesis of sensorimotor neurodevelopmental deficits in macaque infants exposed to Zika virus in uteroNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,025,789June 1, 2020May 31, 2026MOHR, EMMA Lreporter.nih.gov
Early cardiac progenitorsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,025,531July 1, 2013July 31, 2029BRUNEAU, BENOIT GAETANreporter.nih.gov
Heightened hypoxia and DNA methylation in heart defects of diabetic embryopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,020,733September 15, 2022July 31, 2027YANG, PEIXINreporter.nih.gov
Mechanisms and rescue of craniosynostosis associated with gene-environment interactionNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,011,888July 1, 2021April 30, 2027CHEN, JIANFUreporter.nih.gov
In vivo Characterization of Regulatory Variant Pathogenicity in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,998,900January 1, 2022December 31, 2026VISEL, AXELreporter.nih.gov
Clinical Trial Readiness for Children 0-5 years with Congenital Muscular Dystrophy Secondary to LAMA2 MutationsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,998,564September 18, 2023August 31, 2028CONNOLLY, ANNE Mreporter.nih.gov
Pax6 as a key regulator of lens developmentNIHNational Eye Institute2021 to 2025$2,996,871January 1, 2000May 31, 2026CVEKL, ALESreporter.nih.gov
Development of Gene Replacement Therapy for Sanfilippo Syndrome Type CNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,990,505September 19, 2022August 31, 2025SINGAMSETTY, SRIKANTHreporter.nih.gov
Development of an oxygen delivery biotherapeutic for the preservation of myocardial function during pediatric cardiopulmonary bypassNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,986,551August 1, 2017August 31, 2027WINGER, JONATHAN Areporter.nih.gov
Blood vessel assembly from multipotent hemangioma-derived stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,982,138April 1, 2009April 30, 2028BISCHOFF, JOYCE E.reporter.nih.gov
A Randomized, Double-Blind, Placebo-controlled Clinical Trial of Choline Supplementation during Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive DevelopmentNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,980,724May 1, 2020April 30, 2026JACOBSON, SANDRA W.reporter.nih.gov
Specialized Translational Control of Stem Cell Differentiation and Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,979,836March 15, 2016March 31, 2026BARNA, MARIAreporter.nih.gov
Novel role of urinary urate in renal cystogenesis and water regulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,967,657September 1, 2025August 31, 2029CHEBIB, FOUAD Treporter.nih.gov
Defining disease mechanisms in SLC35A2 epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,951,492July 1, 2020April 30, 2025HEINZEN, ERIN Lreporter.nih.gov
Microphthalmia, Anophthalmia, and Coloboma Genetic Epidemiology in Children (MAGIC) StudyNIHNational Eye Institute2021 to 2024$2,946,040May 1, 2021April 30, 2026LUPO, PHILIPreporter.nih.gov
Wnt Signaling and Vertebrate embryogenesisNIHNational Institute of General Medical Sciences2021 to 2024$2,936,224January 1, 2020December 31, 2024HE, XIreporter.nih.gov
Non-invasive functional assessment and pathogenesis of Morquio ANIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,932,986May 1, 2021April 30, 2027TOMATSU, SHUNJIreporter.nih.gov
Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,918,081August 15, 2021July 31, 2026LI, PULINreporter.nih.gov
Identification of metabolic alterations during cortical development in a human cellular model for 22q11.2 deletion syndromeNIHNational Institute of Mental Health2022 to 2025$2,912,854January 18, 2022October 31, 2026PASCA, ANCA MIRABELAreporter.nih.gov
A novel treatment of aortic disease in Marfan Syndrome targeting oxidative stress and PKG dysregulationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,911,850April 1, 2016March 31, 2026PILZ, RENATE Breporter.nih.gov
Neurometabolic Outcomes of Different Cardiopulmonary Bypass StrategiesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,911,403February 15, 2021January 31, 2026HANLEY, FRANKreporter.nih.gov
Pharmacologic Contributors to Patent Ductus ArteriosusNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,898,557July 1, 2022June 30, 2027REESE, JOHN JEFFREYreporter.nih.gov
Mapping the ciliary interactome, an extensive protein interaction network underlying human ciliopathiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,888,402September 5, 2016June 30, 2027WALLINGFORD, JOHN Breporter.nih.gov
Role of Cyclohexanone Toxicity in Mediating Congenital Cardiac Surgery OutcomesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,885,985June 1, 2022May 31, 2027JANTZIE, LAUREN LEIGH COONEYreporter.nih.gov
Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of FallotNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,871,936August 1, 2021July 31, 2027EGBE, ALEXANDERreporter.nih.gov
A protein traffic control system that regulates left-right patterning and heart developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,868,559September 1, 2021August 31, 2025ROHATGI, RAJATreporter.nih.gov
Computer Modeling of the Tricuspid Valve in Hypoplastic Left Heart SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,867,475July 20, 2020June 30, 2026JOLLEY, MATTHEWreporter.nih.gov
WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,862,721September 10, 2021August 31, 2026LEE, BRENDANreporter.nih.gov
Genomics of Cleft PalateNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,853,623September 1, 2021May 31, 2026LESLIE-CLARKSON, ELIZABETH JANEreporter.nih.gov
Altered Lymphatic Function and Development in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,838,877June 1, 2016May 31, 2027DATAR, SANJEEV A.reporter.nih.gov
DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITYNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,836,728May 1, 2020April 30, 2028ANTON, EVA Sreporter.nih.gov
Epigenetic regulation in cardiac developmentNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,819,542April 1, 2023March 31, 2030HUANG, YUNreporter.nih.gov
Uncovering inversion formation in the human genome and its impact to disease.NIHNational Institute of General Medical Sciences2021 to 2024$2,819,375May 1, 2020April 30, 2026FONSECA, CLAUDIA CARVALHOreporter.nih.gov
Emerging therapeutic candidates for rare maternally inherited mitochondrial diseases with shared etiologiesNIHNational Center for Advancing Translational Sciences2023 to 2025$2,806,464July 1, 2021August 31, 2027CHIARAMELLO, ANNE ELIANEreporter.nih.gov
Cellular and molecular determinants of DDX3X syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,805,768May 1, 2021April 30, 2026DE RUBEIS, SILVIAreporter.nih.gov
4D Multimodal Image-Based Modeling for Bicuspid Aortic Valve Repair SurgeryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,803,281June 1, 2022May 31, 2027POUCH, ALISON MARIEreporter.nih.gov
Modern Analytics to Improve Quality & Outcome Assessments Following Congenital Heart SurgeryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,799,826June 15, 2022May 31, 2027NORMAND, SHARON-LISE TERESAreporter.nih.gov
RE-ENERGIZE FONTAN - RandomizEd Exercise INtERvention desiGned to MaximIZE Fitness in Pediatric FONTAN patientsNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,798,890March 10, 2020February 28, 2026SELAMET TIERNEY, ELIF SEDAreporter.nih.gov
Sleep-disordered breathing in infants with myelomeningoceleNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,798,528January 15, 2020November 30, 2025BARKS, JOHN Dreporter.nih.gov
An in vivo screen for genes underlying protective neonate respiratory reflexes to identify potential contributors to Sudden Infant Death Syndrome and other congenital respiratory pathophysiologiesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,797,311December 1, 2021November 30, 2026RAY, RUSSELL Sreporter.nih.gov
Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease SeverityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,785,740August 1, 1999August 31, 2026GELB, MICHAEL Hreporter.nih.gov
Understanding Hirschsprung disease using hPSC-derived models of the enteric nervous systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,781,801September 15, 2025September 14, 2029FATTAHI, FARANAKreporter.nih.gov
An expandable polymeric valved conduit to repair congenital heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,774,182December 15, 2020November 30, 2026FERRARI, GIOVANNIreporter.nih.gov
Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,760,413May 1, 2020April 30, 2026YANG, BOreporter.nih.gov
Dissecting single cell dynamics that coordinate neural crest migration and diversificationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,756,503April 1, 2021March 31, 2027SCHILLING, THOMAS Freporter.nih.gov
Retinal-adhesive thermoresponsive gel for AAV-mediated gene delivery to the outer retinaNIHNational Eye Institute2022 to 2025$2,749,546September 30, 2022July 31, 2027SAHEL, JOSE-ALAINreporter.nih.gov
Role of POGLUT2 and POGLUT3 in regulating microfibril structure and functionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,747,391July 1, 2022June 30, 2027HALTIWANGER, ROBERT S.reporter.nih.gov
Expanding on a new paradigm for MRI in pediatric congenital heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,744,758July 15, 2015March 31, 2026FINN, JOHN PAULreporter.nih.gov
Mechanisms of DMP Development and Atrioventricular SeptationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,723,098September 1, 2014August 31, 2027WESSELS, ARNOreporter.nih.gov
Angiopoietin-2 Signaling Targeted Therapeutics for Arteriovenous MalformationsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,722,127April 1, 2022March 31, 2027MEADOWS, STRYDER MEDOAHreporter.nih.gov
Investigation of common disease mechanisms in nonsyndromic and syndromic PKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,712,900April 15, 2002December 31, 2026HARRIS, PETER C.reporter.nih.gov
Biomechanical drivers of cystogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,696,798September 24, 2021July 31, 2025GUSELLA, GABRIELE LUCAreporter.nih.gov
Regulation of DNA methylation by TETs and QSER1NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,694,857September 22, 2022August 31, 2027EVANS, TODD Rreporter.nih.gov
Daily Caloric Restriction in Overweight and Obese Adults with ADPKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,687,567July 1, 2021May 31, 2027NOWAK, KRISTEN LYNNreporter.nih.gov
Pathomechanisms of SCN3A-related neurodevelopmental disorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,674,943December 1, 2020November 30, 2026GOLDBERG, ETHAN Mreporter.nih.gov
A comprehensive map of polycystin channel regulation and its implications in polycystic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,672,628September 15, 2021July 31, 2025DELLING, MARKUS Greporter.nih.gov
Genetics and Pathobiology of Disorders of KeratinizationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,669,422August 3, 2015April 30, 2027CHOATE, KEITH Areporter.nih.gov
Genetic Analysis of Hirschsprung Disease - RenewalNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,654,475April 1, 1991August 31, 2025CHAKRAVARTI, ARAVINDAreporter.nih.gov
Craniofacial microsomia: Accelerating Research and Education (CARE)NIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,650,134May 1, 2020February 28, 2026HEIKE, CARRIE LYNreporter.nih.gov
Down Syndrome Early Childhood Omics, Deep Phenotyping, and Epidemiology in Texas: DECODE IT CohortNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,644,869September 17, 2024May 31, 2029LUPO, PHILIPreporter.nih.gov
Brain Injury and Dysmaturation in Newborns with Congenital Heart Disease Born PretermNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,638,985March 1, 2023February 28, 2028MCQUILLEN, PATRICK SEANreporter.nih.gov
Regulation of Skeletal progenitor cells in Osteogenesis ImperfectaNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,636,174July 13, 2022April 30, 2027PARK, DONGSUreporter.nih.gov
Regulation of Craniofacial Development by ALX Transcription FactorsNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,632,904September 9, 2020August 31, 2025JIANG, RULANGreporter.nih.gov
Streamline assessment of early lethal phenotypes in the mouseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,631,878September 8, 2015August 31, 2025MAGER, JESSEreporter.nih.gov
Off-label drugs in cardiology: evaluating age- and disease-appropriate therapiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,627,273March 1, 2022February 28, 2027POSNACK, NIKKI GILLUMreporter.nih.gov
Deciphering how 3D genome organization orchestrates cardiac cellular identityNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,627,179May 1, 2023April 30, 2030JAIN, RAJANreporter.nih.gov
Clinically Applicable Orofacial Cleft Reconstruction Using Structural, Compositional Biomimetic Bone ScaffoldsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,621,884August 1, 2022July 31, 2027LEE, SANG JINreporter.nih.gov
Cell fate choices by Tbx1 in forming the mammalian heartNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,603,457August 20, 2020April 30, 2029MORROW, BERNICE Ereporter.nih.gov
Marfan Aortic Embryologic Origin Influences Aneurysm FormationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,603,051April 1, 2016March 31, 2027FISCHBEIN, MICHAEL PETERreporter.nih.gov
Genetic Regulatory Network in Craniofacial DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,599,984March 12, 2025January 31, 2030HSU, WEIreporter.nih.gov
Cell polarity and morphogenesis in Xenopus embryosNIHNational Institute of General Medical Sciences2021 to 2025$2,595,273August 1, 2017June 30, 2027SOKOL, SERGEIreporter.nih.gov
Development of an IOP-lowering gene therapy treatment for glaucomaNIHNational Eye Institute2022 to 2025$2,587,720June 1, 2022May 31, 2027LIPINSKI, DANIEL MARKreporter.nih.gov
Synthetic organogenesis: new paradigms in reconstituting human organ development in vitroNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,586,456September 21, 2021August 31, 2026SIMUNOVIC, MIJOreporter.nih.gov
Mechanisms involved in podocyte damage in Alport SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,586,175August 15, 2022May 31, 2027PERIN, LAURAreporter.nih.gov
Biomaterials for embolization and ablation of arterio-venous malformationsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,585,948July 1, 2022June 30, 2027OKLU, RAHMIreporter.nih.gov
Pediatric Heart Disease: Getting from Mutations to TherapeuticsNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,582,324February 15, 2017January 31, 2025GELB, BRUCE Dreporter.nih.gov
Cell lineage and transcriptional analysis of the vertebrate neural plate borderNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,580,495February 1, 2018January 31, 2028BRONNER, MARIANNEreporter.nih.gov
Intervention Strategies for Non-Folate Responsive Neural Tube DefectsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,575,383February 15, 2016July 31, 2025FINNELL, RICHARD H.reporter.nih.gov
Mito-Targeted AAV to treat Leber Hereditary Optic Neuropathy caused by ND4 mutationsNIHNational Eye Institute2021 to 2023$2,570,468March 1, 2019December 31, 2025PORCIATTI, VITTORIOreporter.nih.gov
Regulatory role of PI3K signaling pathways in lens differentiation and functionNIHNational Eye Institute2021 to 2025$2,568,508December 1, 2015April 30, 2030MENKO, A. SUEreporter.nih.gov
Zfp423 Mechanisms in Joubert Syndrome and Related DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,562,908February 1, 2017May 31, 2027HAMILTON, BRUCE Areporter.nih.gov
Establishing Efficacy for the Congenital Heart Disease Physical Activity Lifestyle InterventionNIHNational Institute of Nursing Research2022 to 2025$2,554,158September 23, 2022June 30, 2027JACKSON, JAMIE L.reporter.nih.gov
Mechanistic analysis and allellic genome editing of iPSC-derived dominant LCA modelNIHNational Eye Institute2021 to 2025$2,545,050January 1, 2021November 30, 2025ULLIAN, ERIK Mreporter.nih.gov
Phase IIB Transmural Systems Transcatheter Cavopulmonary Bypass EndograftNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,544,747June 15, 2021November 30, 2024RAFIEE, NASSERreporter.nih.gov
Functional roles of lymphatics in organogenesis and tissue repairNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,543,362January 7, 2021December 31, 2025OLIVER, GUILLERMO Creporter.nih.gov
Measuring cortical plate and subplate thickness in the human fetal brain from magnetic resonance imagesNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$2,534,043September 24, 2021June 30, 2026IM, KIHOreporter.nih.gov
Mechanisms of Clinical and Hemodynamic Response to Pulmonary Vasodilator Therapy in Fontan physiologyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,530,672December 20, 2021November 30, 2026EGBE, ALEXANDERreporter.nih.gov
Mesenchymal Regulation of OsteogenesisNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,523,606September 28, 2004March 31, 2027SCHNEIDER, RICHARD Areporter.nih.gov
Capillary malformation: From somatic GNAQ mutations to disrupted endothelial biologyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,522,214April 1, 2016June 30, 2026BISCHOFF, JOYCE E.reporter.nih.gov
Epigenetic and environmental impact on early embryonic developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,512,500September 20, 2021August 31, 2026SMITH, ZACHARY DYLANreporter.nih.gov
Deciphering Principles of Human Embryonic Patterning in Development and DiseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,512,500September 15, 2022August 31, 2027SOZEN, BERNAreporter.nih.gov
Fine-scale Spatiotemporal Mapping of Cellular Regulatory Networks Directing Heart DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,499,248August 1, 2020July 31, 2025CHI, NEIL Creporter.nih.gov
Beyond Gene Dosage: Understanding Down Syndrome via 4D Genome OrganizationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,496,816September 18, 2020August 31, 2025LI, WENBOreporter.nih.gov
Robust and Rapid 3D High-Resolution Cranial bone imaging for pediatric patients using MRINIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,488,491December 1, 2021November 30, 2026AN, HONGYUreporter.nih.gov
Molecular pathogenesis of congenital heart disease mediated by neural crest and second heart field cellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,484,708May 12, 2022April 30, 2027MORROW, BERNICE Ereporter.nih.gov
Gene therapy for disorders of the extracellular matrixNIHNational Institute of Neurological Disorders and Stroke2023$2,481,348April 1, 2023March 31, 2026GOULD, DOUGLASreporter.nih.gov
NEDD4 in right ventricular developmentNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,473,604September 1, 2021August 31, 2026FANG, XIreporter.nih.gov
Polycystins, cilia, and extracellular vesicles in C. elegansNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,467,492May 1, 2001June 30, 2027BARR, MAUREEN Mreporter.nih.gov
A Single-Cell Resolution Enhancer Atlas of Craniofacial DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,464,810May 1, 2019April 30, 2025VISEL, AXELreporter.nih.gov
A system approach to the analysis of Heterotaxy Candidate GenesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,462,797April 23, 2020January 31, 2025KHOKHA, MUSTAFA Kreporter.nih.gov
Brain lymphatic activation for craniosynostosis and Alzheimer’s diseaseNIHNational Institute of Neurological Disorders and Stroke2024$2,461,369June 1, 2024May 31, 2027CHEN, JIANFUreporter.nih.gov
An integrated human stem cell model for elucidating myocardial-endocardial interactions in cardiac development and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,460,707February 15, 2021January 31, 2027ZHAO, MINGTAOreporter.nih.gov
Obscurin-kinase 1/N-cadherin: a new signaling axis in cardiac structure/functionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,460,554August 5, 2022May 31, 2027KONTROGIANNI-KONSTANTOPOULOS, AIKATERINIreporter.nih.gov
White Matter Protection in the Fetus with Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,459,987April 1, 2020February 28, 2026ISHIBASHI, NOBUYUKIreporter.nih.gov
Elucidating ECM Signaling in Cardiac Organoids with Machine Learning and Single-cell MultiomicsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,451,978May 9, 2022April 30, 2027WU, JOSEPH C.reporter.nih.gov
Morphogenesis: Biophysics and Genetics of Dorsal ClosureNIHNational Institute of General Medical Sciences2021 to 2025$2,451,542July 1, 2018June 30, 2028KIEHART, DANIEL PETERreporter.nih.gov
Role of homocysteine metabolism, endothelial function and microvascular rarefaction on renal disease severity and progression in ADPKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,449,537May 1, 2021March 31, 2026IRAZABAL, MARIA Vreporter.nih.gov
Hermansky-Pudlak syndrome and melanosome formationNIHNational Eye Institute2022 to 2025$2,448,434May 1, 2004June 30, 2027MARKS, MICHAEL Sreporter.nih.gov
Evaluating the Impact of Mutations in Distant-Acting Enhancers in Structural Birth DefectsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,441,988September 21, 2023June 30, 2028PENNACCHIO, LEN ALEXANDERreporter.nih.gov
Intracellular nucleic acid detection in autoimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,440,748May 15, 2010April 30, 2025STETSON, DANIEL Breporter.nih.gov
Genetic Modifiers of Retinal DiseaseNIHNational Eye Institute2022 to 2025$2,439,084March 1, 2022February 28, 2027NISHINA, PATSY Mreporter.nih.gov
Development and Validation of Therapy for Mucopolysaccharidosis IIINIHNational Institute of Neurological Disorders and Stroke2022$2,435,870September 1, 2014June 30, 2025WOOD, JILLreporter.nih.gov
A Gata456 Pipeline of DiscoveryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,169January 10, 2017December 31, 2023EVANS, TODD Rreporter.nih.gov
Molecular Interactions during Neural Crest FormationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,429,629August 1, 2007July 31, 2026GARCIA-CASTRO, MARTIN I.reporter.nih.gov
Phenotype-driven approach to understanding the function of craniofacial regulators using IMPC-generated mouse strainsNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,427,773April 1, 2019June 30, 2023SELLERI, LICIAreporter.nih.gov
Colorado Center of Childhood Liver Disease ResearchNetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,425,994September 15, 2002May 31, 2029SOKOL, RONALD J.reporter.nih.gov
Gaining insights: the effects of the RMK gain-of-function mutations on brain development and neurodevelopmental disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,425,503August 21, 2022July 31, 2027GREEN, TAMARreporter.nih.gov
Gene regulatory networks for heart developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,410,652January 1, 2021December 31, 2025BRUNEAU, BENOIT GAETANreporter.nih.gov
Regulation of dynamic actin networks during epithelial morphogenesisNIHNational Institute of General Medical Sciences2022 to 2025$2,410,153May 13, 2022April 30, 2027HARDIN, JEFFREY Dreporter.nih.gov
A Novel computational approach to optimize Fontan and improve surgical predictabilityNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,410,109February 1, 2022January 31, 2027GOVINDARAJAN, VIJAYreporter.nih.gov
Molecular and Developmental Analysis of HoloprosencephalyNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,403,316August 1, 2015March 31, 2027KRAUSS, ROBERT S.reporter.nih.gov
Atlanta Center for the Childhood Liver Disease Research Network (ChiLDReN)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,403,001March 7, 2005May 31, 2024KARPEN, SAUL J.reporter.nih.gov
Autophagy and its Regulation in Diabetic EmbryopathyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,402,214May 7, 2014February 28, 2026YANG, PEIXINreporter.nih.gov
PKD proteins in endothelial cellsNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,397,306February 15, 2021January 31, 2026JAGGAR, JONATHAN Hreporter.nih.gov
Genetic Variants in Craniofacial DystoniasNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,396,510September 1, 2022May 31, 2027SHARMA, NUTANreporter.nih.gov
2/2 Milrinone for Prevention of Post-Patent Ductus Arteriosus Closure Syndrome in Extremely Preterm Infants (MIDAS Trial) - DCC ResubmissionNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,393,677July 1, 2024June 30, 2029DAS, ABHIKreporter.nih.gov
Small molecule therapeutic for calcific aortic valve diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,378,349August 1, 2023May 31, 2027SRIVASTAVA, DEEPAKreporter.nih.gov
Genetic and Environmental Regulation of Diaphragm Development and Congenital Diaphragmatic HerniasNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,376,535April 1, 2021March 31, 2026KARDON, GABRIELLEreporter.nih.gov
Role of primary cilium-generated signaling in polycystic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,373,193January 15, 2022November 30, 2026MUKHOPADHYAY, SAIKATreporter.nih.gov
Activation of the Angiopoietin-Tie2/TEK Pathway to Treat Ocular Hypertension and GlaucomaNIHNational Eye Institute2021 to 2024$2,366,638May 1, 2016June 30, 2026QUAGGIN, SUSAN E.reporter.nih.gov
Discoidin Domain Receptor 2, β1 Integrins and ECM Control of Bone FormationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,366,359March 12, 2021August 31, 2026FRANCESCHI, RENNY THEODOREreporter.nih.gov
Multi-center, randomized, controlled trial of the feasibility and safety of inhaled hydrogen gas during ECPRNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,366,065September 1, 2022August 31, 2026KHEIR, JOHN NAGIreporter.nih.gov
Intraflagellar Transport Proteins in MiceNIHNational Institute of General Medical Sciences2021 to 2025$2,358,960June 1, 2001January 31, 2027PAZOUR, GREGORY Jreporter.nih.gov
Generation of four-chambered hearts through organoid fusionsNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,358,480September 1, 2024August 31, 2026LI, GUANGreporter.nih.gov
Integrated Microphysiological System of Cerebral Organoid and Blood Vessel for Disease Modeling and Neuropsychiatric Drug screeningNIHNational Center for Advancing Translational Sciences2021 to 2022$2,355,934February 15, 2018January 31, 2025LEONG, KAM Wreporter.nih.gov
Kidney Stone Disease In ADPKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,353,533September 22, 2021June 30, 2027CHONCHOL, MICHEL BENJAMINreporter.nih.gov
Mechanisms of progression of vascular malformation to lymphangiosarcomaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,351,725April 8, 2003June 30, 2027GUAN, JUN-LINreporter.nih.gov
Nonhuman Primate Model of Inherited Photoreceptor DegenerationNIHNational Eye Institute2023 to 2025$2,341,778September 30, 2023March 31, 2027MCGILL, TREVOR JACKSONreporter.nih.gov
Roles of Nebulin in Structure and Function of Striated MuscleNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,336,550August 1, 2022July 31, 2027GRANZIER, HENK L.reporter.nih.gov
Safety and Efficacy of Human Clinical Trials Using Kidney-on-a-Chip Microphysiological SystemsNIHNational Center for Advancing Translational Sciences2022 to 2024$2,334,876July 15, 2020June 30, 2026FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Multi-Tissue Craniofacial Engineering using 3D-BMP9-Notch-Synergized Graphene Citrate Composite ScaffoldsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,334,479April 1, 2021January 31, 2027REID, RUSSELL R.reporter.nih.gov
In vivo Evaluation of Safety and Pharmacology of the Sustained Release Formulation of Dolutegravir in Pre-Conception and Early Stages of Pregnancy in Animal ModelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,332,164September 13, 2019July 31, 2025KOVAROVA, MARTINAreporter.nih.gov
Role and Regulation of Cellular Polarity in Craniofacial SkeletogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,330,991April 1, 2001September 22, 2028SCHILLING, THOMAS Freporter.nih.gov
ATTRACT: Assessment of Temporomandibular JoinT MoRphology, Mechanics, And Mechanobiology in Class II and III Target and Surgical PhenotypesNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,329,996January 15, 2022December 31, 2026YAO, HAIreporter.nih.gov
Etiology and pathogenesis of lethal lung developmental disorders in neonatesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,325,410August 15, 2023May 31, 2027STANKIEWICZ, PAWELreporter.nih.gov
Transcriptome and Network Analysis of Cleft PalateNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,324,762January 1, 2020September 15, 2023JABS, ETHYLIN WANGreporter.nih.gov
Modulation of cystogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,324,556May 1, 2022February 28, 2027ZHOU, JINGreporter.nih.gov
Interdisciplinary approaches for understanding how arsenic and micronutrients affect the epigenome to influence spina bifida riskNIHNational Institute of Environmental Health Sciences2023 to 2025$2,321,700January 20, 2023December 31, 2026MAZUMDAR, MAITREYIreporter.nih.gov
Transcriptional control of growth plate chondrocytesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,317,204May 15, 2022April 30, 2027LEFEBVRE, VERONIQUE Mreporter.nih.gov
Control of bone physiology by a novel type of adipose cellsNIHNational Institute on Aging2021 to 2025$2,313,640May 15, 2021February 28, 2027QIN, LINGreporter.nih.gov
Role of Slc25a32 and Its Interaction with Lrp6 in the Etiology of Neural Tube DefectsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,311,197March 10, 2020February 28, 2025LEI, YUNPINGreporter.nih.gov
Leveraging Ethnic Anotia-microtia Disparities for Discovery (LEADD) StudyNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,311,053July 31, 2023February 29, 2028SCHRAW, JEREMYreporter.nih.gov
The role of continuous phenotypic variation in structural defects of the faceNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,309,050July 23, 2010November 30, 2026MARCUCIO, RALPH Sreporter.nih.gov
Cellular Mechanisms in Fetal Alcohol Spectrum DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,304,997December 15, 2018May 31, 2029PARNELL, SCOTTreporter.nih.gov
Bioresorbable zinc-based drug-eluting stents for pediatric cardiovascular applicationsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,301,324June 1, 2018July 31, 2028ZHU, DONGHUIreporter.nih.gov
Mapping cell fate flow and feedback control on vertebrate embryonic landscapesNIHNational Institute of General Medical Sciences2021 to 2024$2,299,497September 23, 2021August 31, 2026WAGNER, DANIEL Ereporter.nih.gov
Creating high-resolution multi-omics molecular atlases for developing urogenital organsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,298,845September 30, 2021July 31, 2027CHEN, FENGreporter.nih.gov
Epitranscriptomic Alteration and Planar Cell Polarity Signaling In Diabetic EmbroyopathyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,294,873September 21, 2020July 31, 2025REECE, E. ALBERTreporter.nih.gov
Cell Therapy for Neuroprotection in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,294,475December 15, 2017April 30, 2027ISHIBASHI, NOBUYUKIreporter.nih.gov
Genetic and Hemodynamic Effects on Prenatal Cortical Development in Congenital Heart DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,289,171July 1, 2020March 31, 2026IM, KIHOreporter.nih.gov
Reduction of Brain AVM Severity through Inhibition of Pathogenic AngiogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,278,943February 1, 2020January 31, 2026SU, HUAreporter.nih.gov
Flow regulation of the Alk1/Eng pathway in vascular homeostasis and diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,277,780July 15, 2023May 31, 2027EICHMANN, ANNE CHRISTINEreporter.nih.gov
Mechanisms of Ciliary Signaling Controlling Obesity and Metabolic DiseaseNIHNational Institute of General Medical Sciences2022 to 2025$2,274,616March 1, 2017April 30, 2026JACKSON, PETER KENTreporter.nih.gov
Function and regulation of chromatin remodeling complexes in cardiac development and diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,274,375September 15, 2022July 31, 2026CONLON, FRANK LEOreporter.nih.gov
C. elegans Gastrulation: a Model for Understanding Apical Constriction MechanismsNIHNational Institute of General Medical Sciences2021 to 2025$2,274,307January 1, 2020December 31, 2028GOLDSTEIN, ROBERT Preporter.nih.gov
Molecular Dissection of the 22q11.2 Deletion SyndromeNIHNational Institute of General Medical Sciences2021 to 2024$2,272,016August 15, 2018August 31, 2025EMANUEL, BEVERLY Sreporter.nih.gov
MicroRNA regulation of neural tube closureNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,271,604March 10, 2020February 28, 2025PARCHEM, RONALD Jreporter.nih.gov
Neurodevelopmental defects of the thalamocortical pathway as a convergent feature of psychiatric disordersNIHNational Institute of Mental Health2023 to 2025$2,271,274May 1, 2023January 31, 2028NOWAKOWSKI, TOMASZreporter.nih.gov
Modeling uniquely human developmental gene regulatory networks using humanized miceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,266,740June 10, 2020February 28, 2026NOONAN, JAMES Preporter.nih.gov
Defining non-genetic mechanisms that prevent death in a Hirschsprung disease mouse modelNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,261,547August 27, 2021May 31, 2026HEUCKEROTH, ROBERT Oreporter.nih.gov
Tafazzin and metabolic reprogramming during cardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,259,577September 1, 2021August 31, 2025CONWAY, SIMON JAMESreporter.nih.gov
Structure-Function Studies of Aquaporin 0 in Lens Development and PhysiologyNIHNational Eye Institute2021 to 2025$2,258,153February 1, 2021January 31, 2027TOBIAS, DOUGLAS Jreporter.nih.gov
Chronic Health Conditions in Survivors of Down Syndrome-Associated LeukemiaNIHNational Cancer Institute2022 to 2025$2,251,638June 20, 2022May 31, 2028GRAMATGES, MARIA MONICAreporter.nih.gov
Epigenetics of inner ear neurosensory cell developmentNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,250,638July 1, 2020June 30, 2025MARTIN, DONNA M.reporter.nih.gov
Decoding the mechanisms of cell-cell fusion - Renewal - 1NIHNational Institute of General Medical Sciences2021 to 2025$2,246,895May 4, 2020April 30, 2030CHEN, ELIZABETH Hreporter.nih.gov
Identifying the RNA Splicing and Gene Expression Changes that Cause Congenital Myotonic Dystrophy (Renewal)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,243,012April 1, 2018July 31, 2029JOHNSON, NICHOLAS ELWOODreporter.nih.gov
Regulation of SAMHD1 antiviral activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,242,957September 20, 2016June 30, 2025DIAZ-GRIFFERO, FELIPEreporter.nih.gov
Genetic Basis of Dorso-Ventral Patterning in the Drosophila EyeNIHNational Eye Institute2021 to 2025$2,241,926August 1, 2021June 30, 2027SINGH, AMITreporter.nih.gov
Brain development phenotyping of IMPC lethal mutant miceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,240,058September 1, 2020June 30, 2026DWYER, NOELLE Dreporter.nih.gov
Innovative Approaches to Treating Alport SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,233,451September 22, 2021June 30, 2027MINER, JEFFREY Hreporter.nih.gov
Shared Reading Intervention for Children with Oral CleftsNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,231,030September 10, 2021August 31, 2028COLLETT, BRENT RUSSELLreporter.nih.gov
A comparative effectiveness study of speech and surgical treatments using a Cleft Palate Registry/Research Outcomes Network.NIHNational Institute of Dental & Craniofacial Research2021 to 2022$2,228,849March 1, 2018February 28, 2026CHAPMAN, KATHY Lreporter.nih.gov
Oxylipin Signaling in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,228,649January 1, 2021November 30, 2026AGUIRRE, AITORreporter.nih.gov
Retinal Contributions to Vision Loss in AlbinismNIHNational Eye Institute2022 to 2025$2,224,859July 1, 2022June 30, 2027CARROLL, JOSEPHreporter.nih.gov
TASK ORDER FOR TWO NATIONAL INFORMATION CLEARNINGHOUSESNIHNational Heart, Lung, and Blood Institute2023 to 2024$2,222,528January 15, 2023June 14, 2024ROBINSON, NATEreporter.nih.gov
Novel Approaches to Therapy of Muscle Ion ChannelopathiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,214,757April 1, 2019February 28, 2030RICH, MARK Mreporter.nih.gov
Molecular Mechanism of the Cytoplasmic Dynein-Dynactin Motor ComplexNIHNational Institute of General Medical Sciences2021 to 2025$2,212,300August 1, 2012March 31, 2027GENNERICH, ARNEreporter.nih.gov
Genetic, Tissue, and Anatomical Interactions in Mandibulofacial DysmorphogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,211,956September 1, 2021July 31, 2024JABS, ETHYLIN WANGreporter.nih.gov
Optogenetic regulation of intra-ciliary calcium signaling in cardiac situs developmentNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,193,015July 1, 2022June 30, 2027YUAN, SHIAULOUreporter.nih.gov
Acute Imposition of Fontan Physiology in The Single Ventricle Patient: Effects on Fibrosis, Function and Drug InterventionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,190,858July 1, 2020June 30, 2026FOGEL, MARK Areporter.nih.gov
Primary Cilia: A Novel Signaling Gateway To Neural Circuit ModulationNIHNational Institute of Mental Health2025$2,189,936August 19, 2022May 31, 2027ANTON, EVA Sreporter.nih.gov
The Risk of Acquired Neonatal Significant brain Injury during perinatal Transition in Congenital Heart Disease: TRANSIT CHD studyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,188,348May 1, 2022February 28, 2027PEYVANDI, SHABNAMreporter.nih.gov
The role of RNA binding proteins in heart development and congenital heart defectsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,181,968April 12, 2023April 30, 2027KUYUMCU-MARTINEZ, MUGE NESLIHANreporter.nih.gov
Systematic Identification and Phenotypic Characterization of causal genetic variants in Rare Disease-Associated Birth DefectsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,179,104December 21, 2022November 30, 2027YOUNGER, SCOTT Treporter.nih.gov
An immunomodulatory approach to improve oral cavity wound healingNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,169,288April 1, 2020March 31, 2025GOUDY, STEVEN Lreporter.nih.gov
Genetic underpinnings of craniofacial disorders explored with spatial sequencingNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,169,288August 1, 2023May 31, 2028RUOHOLA-BAKER, HANNELEreporter.nih.gov
NPHP2 in ciliary function, renal fibrosis and cyst formationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,168,386September 15, 2017April 30, 2027SUN, ZHAOXIAreporter.nih.gov
Novel function of a mitochondria phosphatase in cardiac developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,163,950July 1, 2021June 30, 2025CHEN, JUreporter.nih.gov
Neurodevelopment and Psychosis in the 22q11.2 Copy Number VariantsNIHNational Institute of Mental Health2023 to 2025$2,163,535December 14, 2009April 30, 2028BEARDEN, CARRIE Ereporter.nih.gov
Template-based replication of the centriole organelleNIHNational Institute of General Medical Sciences2021 to 2025$2,163,020August 1, 2009December 31, 2027TSOU, MENG-FU BRYANreporter.nih.gov
The Role of NMD in Cortical Neural Progenitor CellsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,162,010December 1, 2021November 30, 2026ZHENG, SIKAreporter.nih.gov
Cardiovascular potassium channels: From molecular basis to disease therapeuticsNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,160,901January 1, 2024December 31, 2030NICHOLS, COLIN Greporter.nih.gov
PKD1 derepression as a potential therapy for Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,160,777September 1, 2022May 31, 2027PATEL, VISHALreporter.nih.gov
Non-coding RNA regulation of early neural developmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,159,490December 1, 2019November 30, 2025NISWANDER, LEE A.reporter.nih.gov
Ion Channel Function and Regulation of the Polycystin-1/2 Complex in Kidney Physiology and Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,154,216July 1, 2020May 31, 2026QIAN, FENGreporter.nih.gov
Interplay between mechanical forces and retinoic acid in lung developmentNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,150,300January 1, 2022November 30, 2026NELSON, CELESTE Mreporter.nih.gov
Mechanistic clinical trial of β-blocker administration for reactivating cardiomyocyte division in Tetralogy of FallotNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,148,915July 1, 2021January 31, 2024KUHN, BERNHARDreporter.nih.gov
Genomic Risk Variants in Orofacial Clefting: Discovery and Functional ValidationNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,147,454December 21, 2022November 30, 2027MARAZITA, MARY L.reporter.nih.gov
Mechanisms of mechanotransduction during neural tube morphogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,145,119September 1, 2022June 30, 2027LU, XIAOWEIreporter.nih.gov
Dissecting and targeting lysosomal signaling in kidney tumorigenesisNIHNational Cancer Institute2022 to 2025$2,144,296March 21, 2022February 28, 2027ZONCU, ROBERTOreporter.nih.gov
Protein tyrosine phosphatase non-receptor 14 in vascular stability and remodelingNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,141,603March 15, 2023February 28, 2027AKHURST, ROSEMARY Jreporter.nih.gov
Understanding Genetic Complexity in Spina BifidaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,136,543September 12, 2023August 31, 2028ROSS, MARGARET ELIZABETHreporter.nih.gov
Mechanism and Function of Cardiac Transcriptional Repression NetworksNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,136,223July 16, 2021June 30, 2025CONLON, FRANK LEOreporter.nih.gov
Investigating the role of genes, maternal exposures, and interactions on orofacial cleftsNIHNational Institute of Dental & Craniofacial Research2022 to 2024$2,134,032July 15, 2022April 30, 2026SHAFFER, JOHN Rreporter.nih.gov
Molecular Pathobiology of Alport SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,132,321September 15, 2022April 30, 2027HUDSON, BILLY GERALDreporter.nih.gov
Dual Role of TRPV2 in the STING-mediated innate immune responseNIHNational Institute of Allergy and Infectious Diseases2025$2,129,684July 25, 2025June 30, 2029PISTON, DAVID Wreporter.nih.gov
X chromosome regulation and role in aneuploidyNIHNational Institute of General Medical Sciences2021 to 2023$2,120,346May 1, 2019April 30, 2025DISTECHE, CHRISTINE M.reporter.nih.gov
Mechanisms of Sonic Hedgehog Signal TransductionNIHNational Institute of General Medical Sciences2021 to 2025$2,117,185August 1, 2017July 31, 2028OGDEN, STACEY KATHRYNreporter.nih.gov
Development of a Fully-Implantable Ventricular Assist Device for Neonates and Children with Heart Failure - with Magnetic Levitation to Improve HemocompatibilityNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,115,146August 1, 2020June 30, 2025FRAZIER, O. H.reporter.nih.gov
Human Genetics and Molecular Mechanisms of Vein of Galen Aneurysmal MalformationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,114,574July 15, 2020June 30, 2025KAHLE, KRISTOPHERreporter.nih.gov
Epigenetic dysregulation of muscle differentiation in Kabuki syndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,111,652February 2, 2022December 31, 2026GUSSONI, EMANUELAreporter.nih.gov
Protein methylation pathways that control genetic susceptibility to environmental pollutants in the occurrence of craniofacial defectsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,110,596July 1, 2021June 30, 2027XU, JIANreporter.nih.gov
Role of keratin intermediate filaments in skin epithelial differentiation.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,104,207August 9, 2021May 31, 2026COULOMBE, PIERREreporter.nih.gov
Genetic Regulation of Inner, Middle and Outer Ear DevelopmentNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,101,738March 22, 2013November 30, 2025GROVES, ANDREW Kreporter.nih.gov
Hox-Regulated MSCs in Skeletal Development, Growth and Fracture HealingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,099,262July 8, 2022June 30, 2027WELLIK, DENEEN Mreporter.nih.gov
ROS Mechanisms in BAV AortopathyNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,094,708July 1, 2021June 30, 2026GLEASON, THOMAS GILLETTEreporter.nih.gov
Uncertainty aware virtual treatment planning for peripheral pulmonary artery stenosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,093,561July 1, 2023June 30, 2028MARSDEN, ALISON Lreporter.nih.gov
2/2 CORD-CHD: Clamp OR Delay among neonates with Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,091,921April 1, 2023March 31, 2030RICE, MADELINE MURGUIAreporter.nih.gov
DEVELOPMENT OF A PULMONARY FLOW RESTRICTOR FOR HYPOPLASTIC LEFT HEART SYNDROMENIHNational Heart, Lung, and Blood Institute2024 to 2025$2,088,353February 15, 2022March 31, 2026TANG, BEVERLYreporter.nih.gov
A developmental engineering toolbox for controlled epithelial morphogenesisNIHNational Institute of General Medical Sciences2021 to 2025$2,088,018August 1, 2019July 31, 2029HUGHES, ALEXreporter.nih.gov
Understanding and targeting molecular and cellular events responsible for pulmonary arteriovenous malformation development, growth and regressionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,087,563September 1, 2023August 31, 2027SPIEKERKOETTER, EDDA FRAUKEreporter.nih.gov
Structural basis of BBSome-mediated ciliary exitNIHNational Eye Institute2021 to 2023$2,085,339June 1, 2020May 31, 2024NACHURY, MAXENCE Vreporter.nih.gov
Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,084,787August 16, 2022July 31, 2027GARCIA, BENJAMIN Areporter.nih.gov
Human Epilepsy Genetics - Neuronal Migration DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,084,281July 1, 1997November 30, 2024WALSH, CHRISTOPHER A.reporter.nih.gov
Transcriptional regulation of neuronal cell lineage decisions in the developing enteric nervous systemNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,081,926June 15, 2022April 30, 2027BRONNER, MARIANNEreporter.nih.gov
Additive Manufacturing of Patient-Specific Masks and Nasal Prongs to Improve Pediatric Ventilation Outcomes and Reduce Pressure SoresNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,080,370March 1, 2022April 30, 2026BAGWELL, ROGER BROOKSreporter.nih.gov
Proteoglycan Metabolism During Cardiac Valve Development and DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,080,075January 1, 2022December 31, 2026KERN, CHRISTINE BRUINSreporter.nih.gov
Nephronophthisis-related ciliopathies and ciliary specializationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,071,959February 15, 2023December 31, 2026BARR, MAUREEN Mreporter.nih.gov
Transcriptional regulatory landscapes underlying FEZ FormationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,070,849March 11, 2020February 28, 2026MARCUCIO, RALPH Sreporter.nih.gov
Mobile Three-Dimensional Screening for Cranial MalformationsNIHNational Institute of Dental & Craniofacial Research2022 to 2024$2,070,785September 1, 2023February 28, 2026AALAMIFAR, FERESHTEHreporter.nih.gov
Linking State Medicaid and Congenital Heart Surgical Registry Data: Building Capacity to Assess Disparities in Longitudinal Outcomes and Value for Children with Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,070,625January 5, 2020June 30, 2030ANDERSON, BRETT ROMEOreporter.nih.gov
5 D impulse mapping in the embryonic heartNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,066,665January 1, 2023December 31, 2026ROLLINS, ANDREW MARTINreporter.nih.gov
A Study Evaluating the Safety and Efficacy of Second-Generation Tissue Engineered Vascular Grafts (TEVG2)NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,061,658September 11, 2019February 28, 2026BREUER, CHRISTOPHER KANEreporter.nih.gov
Olfactory and facial markers of developmental risk for psychosis in 22q11 deletion syndromeNIHNational Institute of Mental Health2021 to 2024$2,059,648September 24, 2019January 31, 2025ROALF, DAVID Rreporter.nih.gov
Positive Airway Pressure For The Treatment Of The Obstructive Sleep Apnea Syndrome In Children With Down SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,055,867September 23, 2019June 30, 2023TAPIA, IGNACIO ESTEBANreporter.nih.gov
Molecular and Functional Analysis of Hirschsprung Defects in Humans and MouseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,054,821April 15, 2020March 31, 2025DAVIS, BRIAN Mreporter.nih.gov
Balancing Airway Progenitor versus Progeny: a Pathway from MitochondriaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,054,106August 20, 2021June 30, 2026SUN, XINreporter.nih.gov
Molecular, material, and structural design principles of centrosomesNIHNational Institute of General Medical Sciences2021 to 2025$2,049,896August 1, 2021July 31, 2026WOODRUFF, JEFFREY Breporter.nih.gov
Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and CiliogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,046,879January 15, 2004June 30, 2028PREKERIS, RYTISreporter.nih.gov
A Mass Spectrometry Approach to the Genetic and Epigenetic Mechanisms Controlling Neuronal IdentityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,046,607March 1, 2020January 31, 2026DAHMANE, NADIAreporter.nih.gov
Longitudinal mapping of brain-face-behavior trajectories in prenatal alcohol exposure from birth through adolescenceNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,045,919September 20, 2018March 31, 2029JOSHI, SHANTANU H.reporter.nih.gov
Wnt Signaling in Cardiac Conduction and ArrhythmogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,037,430January 1, 2016February 28, 2026RENTSCHLER, STACEY LYNNreporter.nih.gov
Aortic Valve Disease: Mechanisms and Therapeutic ApproachesNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,037,372February 10, 2020January 31, 2025SRIVASTAVA, DEEPAKreporter.nih.gov
Molecular control of mechanical forces driving buckling morphogenesis of the small intestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,034,943August 1, 2022May 31, 2027NERURKAR, NANDAN Lreporter.nih.gov
Plausible Causative Mechanism for Dolutegravir Developmental ToxicityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,023,722September 18, 2019July 31, 2025CABRERA, ROBERT Mreporter.nih.gov
Determining the genetic and social determinants of heart failure and mortality in patients with congenital heart diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,019,406July 1, 2023January 31, 2026LANDSTROM, ANDREW P.reporter.nih.gov
Pathogenic Mechanisms of Craniometaphyseal DysplasiaNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,018,261July 1, 2022June 30, 2027CHEN, I-PINGreporter.nih.gov
Investigating the intracellular vesicle-mediated mechanism contributing to cerebral cavernous malformationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,017,643April 1, 2021January 16, 2026ZHOU, JENNY HUANJIAOreporter.nih.gov
Multimodal AI for Precise Clinical and Genetic Diagnosis of Congenital Heart DiseaseNIHOffice of the Director, National Institutes of Health2025$2,013,196September 8, 2025September 7, 2026MILOSAVLJEVIC, ALEKSANDARreporter.nih.gov
Clinical benefits and mechanism of action of angiotensin-II receptor blocker on Cardiovascular remodeling in patients with repaired coarctation of aortaNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,012,689August 25, 2023July 31, 2028EGBE, ALEXANDERreporter.nih.gov
Identification of new therapeutic targets for ADPKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,012,444September 1, 2021June 30, 2025SKOLNIK, EDWARD Yreporter.nih.gov
Thinking outside the cell: Leveraging HuBMAP data to build the human ECM atlasNIHNational Human Genome Research Institute2022 to 2025$2,010,000July 1, 2022April 30, 2026NABA, ALEXANDRAreporter.nih.gov
A Gene-Network Discovery Approach to Structural Brain DisordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,006,305September 15, 2023May 31, 2028LOUVI, ANGELIKIreporter.nih.gov
Gene Mutation and Rescue in Human Diaphragmatic HerniaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$2,005,141August 29, 2011April 30, 2024DONAHOE, PATRICIA Kreporter.nih.gov
Connexin Function and Mechanisms of Cx26 Deficiency Induced Hearing LossNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,004,730July 19, 2021May 31, 2027ZHAO, HONG-BOreporter.nih.gov
Novel ocular imaging and molecular analysis of anterior eye segment for glaucomaNIHNational Eye Institute2023 to 2025$2,003,442March 1, 2023February 29, 2028KUME, TSUTOMUreporter.nih.gov
Psychosis-related Physiological and Neuronal Phenotypes in 22q11 Deletion SyndromeNIHNational Institute of Mental Health2021 to 2023$1,997,858September 1, 2019September 30, 2024CUBELLS, JOSEPH F.reporter.nih.gov
Identification and molecular characterization of somatic mutations in MCDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,992,437September 30, 2016May 31, 2028HEINZEN, ERIN Lreporter.nih.gov
Trophic interactions directing proper kidney developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,991,995February 21, 2020May 31, 2030O'BRIEN, LORI Lreporter.nih.gov
Change of InstitutionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,991,250January 1, 2017June 30, 2024BURNS, CAROLINE Ereporter.nih.gov
Lipid Peroxidation-Induced Mitochondrial Injury Inhibits Vascular Function in Single Ventricle Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,984,499July 1, 2023May 31, 2027REDDY, SUSHMAreporter.nih.gov
1/2 percutaneous intervention versus observational trial of arterial ductus in lower gestational age infants (PIVOTAL)NIHNational Heart, Lung, and Blood Institute2023 to 2025$1,979,315March 21, 2022February 28, 2027BACKES, CARLreporter.nih.gov
CranioRate: An imaging-based, deep-phenotyping analysis toolset, repository, and online clinician interface for craniosynostosisNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,979,312September 1, 2023August 31, 2028ELHABIAN, SHIREEN YOUSSEFreporter.nih.gov
Integrating Volumetric Light-Field with Computational Fluid Dynamics to Study Myocardial Trabeculation and FunctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,975,848August 1, 2021May 31, 2026HSIAI, TZUNG Kreporter.nih.gov
Molecular mechanisms and treatment of cardiomyopathy in Barth SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,974,688April 1, 2021March 31, 2026FANG, XIreporter.nih.gov
Prenatal Environment And Child Health (PEACH) in ECHONIHOffice of the Director, National Institutes of Health2025$1,973,808September 1, 2023May 31, 2030SCHMIDT, REBECCA JEANreporter.nih.gov
Engineered Neuroprotective Stem-Cell Exosomes for In Utero Spina Bifida TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,972,069September 30, 2020August 31, 2025FARMER, DIANA LEEreporter.nih.gov
Neural representation of mating partners by male C. elegansNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,970,487August 15, 2019October 31, 2024STERNBERG, PAUL WARRENreporter.nih.gov
Discovery Pipeline for Genetic Defects in Hypothalamic-pituitary Development Using International Mouse Phenotyping Consortium MiceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,970,408May 23, 2023April 30, 2027CAMPER, SALLY A.reporter.nih.gov
Brain pathology and function in a chronic mouse model of ZIKV transmissionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,965,040April 1, 2019March 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
Clinical genetics of drug-resistant epilepsy with focal cortical dysplasiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,963,087April 15, 2021June 30, 2023LAL, DENNISreporter.nih.gov
Targeted therapy to reverse aortic aneurysmsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,959,963April 1, 2017March 31, 2027VYAVAHARE, NAREN Rreporter.nih.gov
Development of Stop Consonants in Children with Repaired Cleft PalateNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,959,879April 4, 2013March 31, 2026ZAJAC, DAVID Jreporter.nih.gov
Improving high-risk infant care: from Hospital to Home with Neoneur TelehealthNIHNational Institute of Nursing Research2022 to 2023$1,959,107March 3, 2022July 31, 2025HOEDEMAKER, CAROLINEreporter.nih.gov
Epigenetic-mediated Notch pathway activation promotes elastin aortopathyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,957,640February 1, 2023January 31, 2028GREIF, DANIELreporter.nih.gov
Injury Response Mediated Pathogenesis in Renal CiliopathiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,950,967February 1, 2023November 30, 2026YODER, BRADLEY K.reporter.nih.gov
Pluripotent Stem Cell Derived 3D Retinas for Studies of Early Onset Retinal DegenerationNIHNational Eye Institute2021 to 2024$1,950,685April 1, 2020March 31, 2026WAHLIN, KARL Jreporter.nih.gov
Intersection of the mTOR/p70S6K1 signaling and the HIPPO-Yap tissue organizer in neurulation and diabetic embryopathyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,948,955December 21, 2022November 30, 2027YANG, PEIXINreporter.nih.gov
Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleftNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,948,725February 15, 2023January 31, 2028LIAO, ERIC CHIEN-WEIreporter.nih.gov
Genomic Effects on Right Ventricular Function, Clinical Features and Outcomes in CHDNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,948,211September 30, 2009July 31, 2025NEWBURGER, JANE W.reporter.nih.gov
Identification of Potential Biomarkers and Clinical Tools for use in Mucopolysaccharidosis IIIC Patients.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,944,180July 1, 2024June 30, 2027SINGAMSETTY, SRIKANTHreporter.nih.gov
Genetic and extrinsic mechanisms governing early enteric nervous system developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,941,485March 27, 2021February 28, 2027URIBE, ROSA Areporter.nih.gov
Structure and Function of Complexes that Regulate Ciliary MotilityNIHNational Institute of General Medical Sciences2021 to 2025$1,939,213September 28, 2007February 29, 2028NICASTRO, DANIELAreporter.nih.gov
Dual roles of Nell-1 in craniofacial bones and brain through interaction with Cntnap4NIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,936,998August 1, 2020July 31, 2025SOO, CHIAreporter.nih.gov
Molecular and cell biological basis of convergent extensionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,934,505June 1, 2025April 30, 2030WALLINGFORD, JOHN Breporter.nih.gov
The systems developmental biology of zebrafish body elongationNIHNational Institute of General Medical Sciences2023 to 2025$1,929,446January 1, 2023December 31, 2027HOLLEY, SCOTT Areporter.nih.gov
The Roles of Neural Crest Derived Cardiomyocytes in Adult-Onset Heart Failure and RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,928,505February 15, 2020January 31, 2026TRISTANI-FIROUZI, MARTINreporter.nih.gov
Developmental regulation of lens gene expressionNIHNational Eye Institute2021 to 2024$1,924,100April 1, 2003April 30, 2026CVEKL, ALESreporter.nih.gov
The crosstalk of DNA and lysine methyltransferases in ADPKD.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,917,952September 15, 2020July 31, 2026LI, XIAOGANGreporter.nih.gov
Endothelial subpopulations in heart valve development and congenital heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,915,051December 15, 2020November 30, 2025YUTZEY, KATHERINE Ereporter.nih.gov
Mechanisms of Abnormal Diaphragm and Cardiac DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,910,630July 1, 2020April 30, 2025SCOTT, DARYL ARMSTRONGreporter.nih.gov
Accelerating research to advance care for adults with congenital heart disease through development of validated scalable computational phenotypesNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,910,551July 10, 2020May 31, 2025OPOTOWSKY, ALEXANDER R.reporter.nih.gov
Transposable Element Interaction and Its Impact on Human Development and HealthNIHOffice of the Director, National Institutes of Health2022 to 2025$1,909,873September 15, 2022August 31, 2027XIA, BOreporter.nih.gov
Multi-organism platform for functional assessment of human birth defect associated genomic variantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,906,531December 20, 2022November 30, 2027SOLNICAKREZEL, LILIANNAreporter.nih.gov
Gene regulatory network controlling neural crest derived formation of facial cartilageNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,903,262June 1, 2014March 31, 2026BRONNER, MARIANNEreporter.nih.gov
Molecular Determinants of Pigmentation (MDoP)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,895,636July 15, 2021November 30, 2026AHMED, ZUBAIR M.reporter.nih.gov
Establishing and Mimicking Patterning Mechanisms in the Distal Nephron Tubule and Kidney OrganoidNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,891,016August 1, 2023June 30, 2028LINDSTROM, NILS OLOFreporter.nih.gov
BCM/TCH Cholestatic Liver Disease ConsortiumNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,886,576September 10, 2014May 31, 2029SHNEIDER, BENJAMIN Lreporter.nih.gov
BMP and Notch crosstalk in cerebral arteriovenous malformationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,885,175June 1, 2012May 31, 2027YAO, YUCHENGreporter.nih.gov
Hedgehog signaling at the cell's antenna: Smoothened and the primary ciliumNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,880,954July 15, 2007June 30, 2025REITER, JEREMY Freporter.nih.gov
Coronary artery dysfunction in OSA: Role of mineralocorticoid receptorsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,880,847June 1, 2023May 31, 2028BADRAN, MOHAMMADreporter.nih.gov
Mechanism of Wnt5a signaling in skeletal development and diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,878,910August 15, 2022May 31, 2028WANG, JIANBOreporter.nih.gov
Measuring and modeling the dynamics ofpatterning in human stem cellsNIHNational Institute of General Medical Sciences2021 to 2025$1,875,174January 11, 2019July 31, 2027RAMANATHAN, SHARADreporter.nih.gov
Genomic and functional investigations of the transcriptional regulatory network of tooth enamel developmentNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,875,117July 1, 2023June 30, 2028KWON, HYUK JAE EDWARDreporter.nih.gov
Mechanisms governing the differentiation and maintenance of atrial identityNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,871,877April 1, 2023March 31, 2027WAXMAN, JOSHUAreporter.nih.gov
Genetics of human renal hypodysplasiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,871,360April 1, 2008May 31, 2025GHARAVI, ALI Greporter.nih.gov
The Cardiac Atlas ProjectNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,871,310January 1, 2014June 30, 2025MCCULLOCH, ANDREW D.reporter.nih.gov
Functions of chromatin remodeler Chd7 in retinal cell developmentNIHNational Eye Institute2023 to 2025$1,869,476September 30, 2023July 31, 2027MORRIS, ANN Creporter.nih.gov
Role of Glutamine Metabolism During Osteoblast Differentiation and Bone FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,868,808April 1, 2018April 30, 2029KARNER, COURTNEY MICHAELreporter.nih.gov
Drug Eluting Silk Fibroin Grafts for Repair of Long Urethral StricturesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,864,246February 15, 2023December 31, 2026MAUNEY, JOSHUA ROBERTreporter.nih.gov
Activation of Nrf2 during embryonic development - mechanisms and consequencesNIHNational Institute of Environmental Health Sciences2022 to 2025$1,864,170June 1, 2016December 31, 2026TIMME-LARAGY, ALICIA Rreporter.nih.gov
Cis-regulatory circuitry underlying Hedgehog mediated limb developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,863,322August 1, 2012December 31, 2028VOKES, STEVEN ALEXANDERreporter.nih.gov
Long-term Outcomes after Interventions for Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,858,355April 1, 2014July 31, 2025KOCHILAS, LAZAROS K.reporter.nih.gov
Modeling p63-associated human birth defects with systems developmental biology approachesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,849,197September 16, 2022August 31, 2027YI, RUIreporter.nih.gov
Molecular Pathogenesis of Hereditary Hemorrhagic TelangiectasiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,848,384February 1, 2020January 31, 2026WANG, RONGreporter.nih.gov
Neuronal Regulation of Skeletal Development and RepairNIHNational Institute of Dental & Craniofacial Research2022 to 2025$1,847,634February 20, 2023August 31, 2026CLEMENS, THOMAS Lreporter.nih.gov
Hyperglycemia of Maternal Diabetes Induces Cardiac Isl1 Positive Progenitor Dysfunction Leading to Heart DefectsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,845,222August 28, 2020June 30, 2025YANG, PEIXINreporter.nih.gov
Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated OutcomesNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,843,596December 15, 2018November 30, 2025SLAUGHTER, JONATHAN LEEreporter.nih.gov
ADPKD: Understanding immunosuppression mechanisms and discovering treatmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,841,779September 1, 2021June 30, 2025LI, XIAOGANGreporter.nih.gov
Targeting TGFb In Osteogenesis ImperfectaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,840,003September 7, 2023June 30, 2028BAE, YANGJINreporter.nih.gov
Analysis of Congenital Hydrocephalus Genes in XenopusNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,831,719June 1, 2022May 31, 2027DENIZ, ENGINreporter.nih.gov
Digoxin Pharmacodynamics in Infants with Heart Failure due to Single Ventricle Congenital Heart DiseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$1,830,595April 1, 2022February 28, 2027HORNIK, CHRISTOPHreporter.nih.gov
MECHANISTIC BASIS FOR REGIONAL PREDISPOSITION FOR ANEURYSMNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,825,653August 1, 2019July 31, 2025GALLO MACFARLANE, ELENAreporter.nih.gov
Structural, mechanical, and cell biological properties of the ciliary zonuleNIHNational Eye Institute2021 to 2025$1,815,956June 1, 2018February 29, 2028BASSNETT, STEVENreporter.nih.gov
The Role of Macrophages in Hepatobiliary DevelopmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,815,657May 1, 2023March 31, 2028GOESSLING, WOLFRAMreporter.nih.gov
Diversification of cell types during male and female external genital developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,815,494September 30, 2021July 31, 2026COHN, MARTIN Jreporter.nih.gov
FUNCTIONAL CHARACTERIZATION OF NOVEL DETERMINANTS OF HOLOPROSENCEPHALY (HPE)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,814,013March 5, 2021February 28, 2026GUCCIONE, ERNESTOreporter.nih.gov
Gene Regulatory Networks that Establish Mandible and Maxilla PatterningNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,812,123August 1, 2020July 31, 2025CLOUTHIER, DAVID E.reporter.nih.gov
Molecular and cellular basis of the renal diseases associated with Alagille SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,811,392May 1, 2021February 28, 2027SURENDRAN, KAMESWARANreporter.nih.gov
Identifying and applying genetic variation relevant to clinical outcomes for individuals with congenital heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,810,339August 1, 2020July 31, 2025SHEN, YUFENGreporter.nih.gov
Cellular Stress-Induced Gene Dysregulation in Heart Defects Formation of Diabetic PregnancyNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,809,936July 1, 2020June 30, 2025YANG, PEIXINreporter.nih.gov
Establishing an In Vitro Embryotoxicity Risk Classification System Based on Human Cardiac Organoid ModelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,809,852April 1, 2020November 30, 2026MA, ZHENreporter.nih.gov
Genetics and Pathobiology of Cutaneous Mosaic DisordersNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,809,250May 1, 2018August 31, 2030CHOATE, KEITH Areporter.nih.gov
Function and regulatory mechanisms of the Wnt5a-Ror morphogenetic pathwayNIHNational Institute of General Medical Sciences2022 to 2025$1,808,362February 1, 2022January 31, 2027HO, HSIN-YI HENRYreporter.nih.gov
Fetal Brain MRI as a Predictor of Late Neurodevelopmental Outcome in Congenital Heart DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,800,997January 1, 2022December 31, 2026ROLLINS, CAITLINreporter.nih.gov
Understanding Cardiac C-Looping Using Microscale In Vitro ModelsNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,800,914July 7, 2021May 31, 2026WAN, LEO Q.reporter.nih.gov
Gene x Environment Interactions and Congenital Heart Defects – Illuminating the MechanismsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,791,765July 21, 2023April 30, 2028ZOHN, IRENE Ereporter.nih.gov
Ketosis as a therapy for polycystic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,790,657April 1, 2020January 31, 2026WEIMBS, THOMASreporter.nih.gov
Resolving Uncertainty in Alagille Syndrome DiagnosticsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,789,630July 1, 2023April 30, 2028SPINNER, NANCY BETTINAreporter.nih.gov
Injury, Progression, and Fibrosis of the Extrahepatic Bile DuctNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,789,450August 1, 2019April 30, 2027WELLS, REBECCA Greporter.nih.gov
Development of novel therapeutic approaches for treatment of Alveolar Capillary DysplasiaNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,783,643May 1, 2021May 31, 2029KALINICHENKO, VLADIMIRreporter.nih.gov
Retinal Patterning During Eye DevelopmentNIHNational Eye Institute2021 to 2025$1,781,988February 1, 2001August 31, 2029MLODZIK, MAREKreporter.nih.gov
Germline mutations of PTPN11 (SHP2) in the stem cell microenvironmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,781,734August 5, 2016June 30, 2026QU, CHENG-KUIreporter.nih.gov
Structural basis of receptor-mediated cellular vitamin A uptakeNIHNational Eye Institute2023 to 2025$1,781,124April 1, 2017April 30, 2028MANCIA, FILIPPOreporter.nih.gov
Role of SPECC1L cytoskeletal protein in palate elevation dynamicsNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,780,609August 10, 2023May 31, 2028SAADI, IRFANreporter.nih.gov
Mechanisms and Treatment of Hajdu Cheney SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,778,744July 1, 2021May 31, 2027CANALIS, ERNESTOreporter.nih.gov
2/2 Percutaneous Intervention Versus Observational Trial of Arterial ductus management in Low-weight infants (PIVOTAL) Data Coordinating CenterNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,778,031March 21, 2022February 28, 2027WISNIEWSKI, STEPHEN Rreporter.nih.gov
Integration of Advanced Diffusion MRI and 3D Histology for Improved Neurosurgical TargetingNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,776,184July 1, 2016May 31, 2028MCNAB, JENNIFER Areporter.nih.gov
IntelliStent: A minimally Invasive, Adjustable Pulmonary Flow Restrictor System for Congenital and Acquired Heart DiseaseNIHNational Heart, Lung, and Blood Institute2025$1,771,084September 1, 2025August 31, 2027BOGNER, SETH ADAMreporter.nih.gov
Continuation of the Childhood Liver Disease Research Network - Seattle Clinical CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,770,356September 10, 2009May 31, 2029VALENTINO, PAMELAreporter.nih.gov
Mechanisms of bone fragility in Autosomal Dominant Osteopetrosis type II: from human to mouse and backNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,769,891September 1, 2022May 31, 2026CHARLES, JULIA Freporter.nih.gov
Targeting CHI3L1 and its receptors in Hermansky-Pudlak Syndrome-associated lung diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,769,742March 20, 2020February 28, 2026ZHOU, YANGreporter.nih.gov
Molecular drivers of tissue-specific morphogenetic programsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,769,567June 22, 2022March 31, 2027WILLIAMS, MARGOT L.K.reporter.nih.gov
Developmental Progression of Youth with Critical Congenital Heart DefectsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,767,874April 1, 2020March 31, 2026VANNATTA, KATHRYNreporter.nih.gov
PeriPath: A Single Incision Delivery Tool for Epicardial Pacing and Defibrillation: Phase 2NIHNational Heart, Lung, and Blood Institute2022 to 2023$1,764,433September 1, 2022August 31, 2025OPFERMANN, JUSTINreporter.nih.gov
Development of gene therapy product for treating MPS IIIBNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,762,240September 1, 2024August 31, 2027MCCARTY, DOUGLAS Mreporter.nih.gov
Alcohol-induced cardiac injury and repair in human induced pluripotent stem cell modelNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,760,250April 20, 2021March 31, 2027XU, CHUNHUIreporter.nih.gov
Molecular Mechanisms of Atrial Development and RegenerationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,759,486July 21, 2017December 31, 2026WAXMAN, JOSHUAreporter.nih.gov
Cellular determinants of cardiopharyngeal multipotency and early fate choicesNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,759,231August 1, 2011May 31, 2024MOGILNER, ALEXANDERreporter.nih.gov
1/2 CORD-CHD: Clamp OR Delay among neonates with Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,758,207April 1, 2023March 31, 2030BACKES, CARLreporter.nih.gov
MR Fingerprinting for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,753,171January 15, 2019December 31, 2024MA, DANreporter.nih.gov
The role of the Foxi3 transcription factor in craniofacial microsomiaNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,750,708March 15, 2023April 30, 2025GROVES, ANDREW Kreporter.nih.gov
Pluripotent stem cell-derived organoid model of human gonad development, functions, and disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,746,338September 18, 2023August 31, 2027JORDAN, PHILIP Wreporter.nih.gov
A Smart, Fully Subcutaneous Distraction System to Improve Outcomes in Patients with Congenital or Acquired Craniofacial DifferencesNIHNational Institute of Dental & Craniofacial Research2023 to 2024$1,742,500September 14, 2023September 13, 2025DESNOYER, JESSICAreporter.nih.gov
Coding and Noncoding RNA Contributions to 22q11.2 Deletion SyndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,737,187July 1, 2015June 30, 2026VAN OERS, NICOLAI STANISLAS CYRILLEreporter.nih.gov
Therapeutic genetics and disease modeling in LAMA2-CMDNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,737,152July 1, 2022May 31, 2027VOCKLEY, GERARDreporter.nih.gov
Shear stress and light-field to elucidate the initiation of cardiac outflow tractNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,736,801July 9, 2015December 31, 2025HSIAI, TZUNG Kreporter.nih.gov
Cilium-associated structures in rod cellsNIHNational Eye Institute2021 to 2024$1,735,948April 1, 2016March 31, 2025WENSEL, THEODORE Greporter.nih.gov
Molecular underpinnings of Prader-Willi syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,733,926September 9, 2019June 30, 2025CARMICHAEL, GORDON Greporter.nih.gov
Regulation of Kidney-Specific Gene ExpressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,731,451November 18, 2022June 30, 2027IGARASHI, PETERreporter.nih.gov
Homeotic hotspot in the human genome for eye and brain diseaseNIHNational Eye Institute2022 to 2025$1,730,360August 1, 2022June 30, 2027GLASER, THOMAS M.reporter.nih.gov
Cfp1 Action in Cartilage DevelopmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,728,659March 1, 2020July 31, 2025CARLONE, DIANA LYNNreporter.nih.gov
Biomechanics of MorphogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,724,197July 1, 2005May 31, 2027DAVIDSON, LANCE A.reporter.nih.gov
Craniofacial skeletal cell lineage plasticity for reconstituting stem cells and their nichesNIHNational Institute of Dental & Craniofacial Research2022 to 2025$1,714,785March 1, 2022February 28, 2027ONO, NORIAKIreporter.nih.gov
Functional and mechanistic characterization of YWHAZ variants associated with human diseasesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,713,090April 1, 2020March 31, 2025CHANG, CHENBEIreporter.nih.gov
Catheter Based Cardiovascular Device Retrieval SystemNIHNational Heart, Lung, and Blood Institute2021$1,708,264September 24, 2018June 30, 2024GORMAN, JOSEPH Hreporter.nih.gov
Molecular and cellular mechanisms of the actin cytoskeleton organization and functionNIHNational Institute of General Medical Sciences2022 to 2025$1,704,179September 1, 2022August 31, 2026KUDRYASHOV, DMITRIreporter.nih.gov
Molecular Basis for Lens TransparencyNIHNational Eye Institute2021 to 2023$1,703,694February 1, 1998June 30, 2025MCHAOURAB, HASSANE Sreporter.nih.gov
Characterization of TMEM251 that causes a new type of severe lysosome storage diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,701,036September 15, 2022August 31, 2027LI, MINGreporter.nih.gov
Redox and Proteomic Stress Responses in Biliary DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,699,864June 15, 2022May 31, 2027PACK, MICHAEL Areporter.nih.gov
Congenital Heart Disease Genetics and Clinical OutcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,698,901September 30, 2009July 31, 2025BRUECKNER, MARTINAreporter.nih.gov
Elucidating pathogenic mechanisms in STRADA-related brain malformation and epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,696,274August 15, 2022June 30, 2027DANG, LOUIS TUONG CHINHreporter.nih.gov
Deep learning for decoding genetic regulation and cellular maps in craniofacial developmentNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,694,464April 1, 2021March 31, 2026ZHAO, ZHONGMINGreporter.nih.gov
Four-dimensional prediction and quantification of how physical forces impact organogenesis in zebrafishNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,691,309September 25, 2020August 31, 2025MANNING, MARY ELIZABETH LISAreporter.nih.gov
The impact of RNA chemical modifications on polycystic kidney disease progressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,686,633May 11, 2015December 31, 2025PATEL, VISHALreporter.nih.gov
FASD Diagnostic Telemedicine ResourceNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,684,699September 15, 2022April 30, 2027GIST, LAURENreporter.nih.gov
Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM StudyNIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,674,517August 1, 2024April 30, 2029MCKINNEY, CHRISTY MICHELLEreporter.nih.gov
Mechanisms of sex-biased risk and resiliency in aneurysm and dissectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,670,000September 16, 2022August 31, 2026PARKER, SARAH Jreporter.nih.gov
The transcriptional regulation of smooth muscle genes by PRDM6 in vascular health and diseasesNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,669,985December 11, 2023November 30, 2027MANI, ARYAreporter.nih.gov
Skin-targeted Cell Therapy for Recessive Dystrophic Epidermolysis BullosaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,669,505April 1, 2013August 31, 2030TOLAR, JAKUBreporter.nih.gov
Bridging the Gap between Genomics and Clinical Outcomes in CHDNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,669,113August 15, 2015July 31, 2025TRISTANI-FIROUZI, MARTINreporter.nih.gov
Sequences controlling H19 Gene ImprintingNIHNational Institute of General Medical Sciences2021 to 2024$1,663,398August 1, 1994June 30, 2025BARTOLOMEI, MARISA S.reporter.nih.gov
MicroRNA regulation of neural crest differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,661,787August 1, 2019May 31, 2025PARCHEM, RONALD Jreporter.nih.gov
Potassium channels, membrane potential, and CHDNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,661,160May 1, 2020April 30, 2024KHOKHA, MUSTAFA Kreporter.nih.gov
The emergence of collective cell behaviors from intercellular interactionsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,660,203June 24, 2022May 31, 2027DEVENPORT, DANELLE Nreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California, San FranciscoSan Francisco, CA80$92.2 million0$0
University of Michigan at Ann ArborAnn Arbor, MI53$81.5 million0$0
Baylor College of MedicineHouston, TX60$73.3 million0$0
Yale UniversityNew Haven, CT67$71.4 million0$0
University of Southern CaliforniaLos Angeles, CA24$67.4 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH54$67.2 million0$0
Boston Children's HospitalBoston, MA65$66.6 million0$0
Stanford UniversityStanford, CA46$62.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC40$46.1 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA37$45.9 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY32$43.1 million0$0
University of Colorado DenverAurora, CO60$43 million0$0
University of Maryland BaltimoreBaltimore, MD26$42 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA45$39.5 million0$0
Washington UniversitySaint Louis, MO38$39.4 million0$0
University of California, San DiegoLa Jolla, CA36$38.7 million0$0
Emory UniversityAtlanta, GA46$36.3 million0$0
Research Inst Nationwide Children's HospColumbus, OH31$36 million0$0
Massachusetts General HospitalBoston, MA27$34.1 million0$0
The Emmes Company, LLCRockville, MD2$32.6 million0$0
Columbia University Health SciencesNew York, NY33$32.2 million0$0
Seattle Children's HospitalSeattle, WA19$31.8 million0$0
Ut Southwestern Medical CenterDallas, TX22$31.3 million0$0
University of PennsylvaniaPhiladelphia, PA42$31.1 million0$0
University of WashingtonSeattle, WA23$30.8 million0$0
University of UtahSalt Lake City, UT24$30.2 million0$0
University of California at DavisDavis, CA28$29.2 million0$0
Johns Hopkins UniversityBaltimore, MD38$28.5 million0$0
Mayo Clinic RochesterRochester, MN23$28 million0$0
University of HawaiiHonolulu, HI5$25.8 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX25$24 million0$0
Albert Einstein College of MedicineBronx, NY16$23.6 million0$0
University of California Los AngelesLos Angeles, CA23$22.9 million0$0
Indiana University IndianapolisIndianapolis, IN24$22.5 million0$0
Northwestern University at ChicagoChicago, IL22$21.3 million0$0
Duke UniversityDurham, NC22$19.2 million0$0
University of Alabama at BirminghamBirmingham, AL18$18.8 million0$0
Brigham and Women's HospitalBoston, MA17$18.2 million0$0
California Institute of TechnologyPasadena, CA17$17.3 million0$0
J. David Gladstone InstitutesSan Francisco, CA9$17 million0$0
Vanderbilt University Medical CenterNashville, TN14$16.9 million0$0
University of Wisconsin-MadisonMadison, WI19$16.9 million0$0
Children's Research InstituteWashington, DC15$16.8 million0$0
Medical College of WisconsinMilwaukee, WI14$16.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY18$15.9 million0$0
University of Texas at AustinAustin, TX20$15.2 million0$0
Princeton UniversityPrinceton, NJ11$15.1 million0$0
University of VirginiaCharlottesville, VA16$14.8 million0$0
University of California-IrvineIrvine, CA15$14.8 million0$0
University of ChicagoChicago, IL10$14.2 million0$0
Case Western Reserve UniversityCleveland, OH12$12.8 million0$0
University of Connecticut SCH of Med/dntFarmington, CT14$12.5 million0$0
SUNY at Stony BrookStony Brook, NY13$12 million0$0
University of MinnesotaMinneapolis, MN18$11.9 million0$0
George Washington UniversityWashington, DC12$11.7 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH13$11.4 million0$0
Oregon Health & Science UniversityPortland, OR12$11.2 million0$0
Harvard Medical SchoolBoston, MA16$11 million0$0
Phoenix Nest, Inc.Brooklyn, NY4$10.9 million0$0
University of IowaIowa City, IA18$10.5 million0$0
Children's Hospital of Los AngelesLos Angeles, CA10$10.5 million0$0
New York University School of MedicineNew York, NY9$10.3 million0$0
Jackson LaboratoryBar Harbor, ME8$10.1 million0$0
University of Massachusetts AmherstAmherst, MA7$9.6 million0$0
University of Kansas Medical CenterKansas City, KS12$9.4 million0$0
University of Miami School of MedicineCoral Gables, FL11$9.1 million0$0
Wayne State UniversityDetroit, MI10$8.9 million0$0
Lurie Children's Hospital of ChicagoChicago, IL10$8.8 million0$0
University of Calif-Lawrenc Berkeley LabBerkeley, CA4$8.7 million0$0
Rutgers University New BrunswickNew Brunswick, NJ5$8.4 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA4$8.1 million0$0
University of Georgia Research Foundation IncAthens, GA7$7.6 million0$0
University of CincinnatiCincinnati, OH8$7.3 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA7$6.9 million0$0
Cornell UniversityIthaca, NY8$6.8 million0$0
Starlight Cardiovascular, Inc.San Diego, CA5$6.7 million0$0
Thomas Jefferson UniversityPhiladelphia, PA6$6.6 million0$0
Iq Solutions, Inc.Rockville, MD2$6.3 million0$0
University of ArizonaTucson, AZ8$6.3 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA9$6.2 million0$0
Amplo Biotechnology, Inc.Towson, MD2$6.2 million0$0
University of DelawareNewark, DE9$6.1 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK10$6 million0$0
University of KentuckyLexington, KY9$5.9 million0$0
University of California-RiversideRiverside, CA6$5.8 million0$0
Medical University of South CarolinaCharleston, SC6$5.6 million0$0
New York UniversityNew York, NY11$5.5 million0$0
Ada Forsyth Institute, Inc.Somerville, MA3$5.4 million0$0
University of California-BerkeleyBerkeley, CA7$5.4 million0$0
Texas A&m University Health Science CTRCollege Station, TX4$5.4 million0$0
Columbia UniversityNew York, NY6$5.4 million0$0
Massachusetts Eye and Ear InfirmaryBoston, MA2$5.3 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY6$5.3 million0$0
Tulane University of LouisianaNew Orleans, LA6$5.1 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ7$5.1 million0$0
Syracuse UniversitySyracuse, NY4$5 million0$0
Boston University Medical CampusBoston, MA7$4.9 million0$0
Virginia Commonwealth UniversityRichmond, VA6$4.9 million0$0
University of Tennessee Health Sci CTRMemphis, TN4$4.8 million0$0
University of Texas at DallasRichardson, TX6$4.7 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025962$455,807,5820$0
20241,045$477,948,8050$0
20231,104$498,414,6740$0
20221,142$493,299,7240$0
20211,087$457,921,8810$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 15 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 10 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 2 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)PA-24-191NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIHJanuary 7, 2028Not listedNotice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.837December 3, 2026Not listedSame assistance listing 93.837 as 472 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.837December 3, 2026Not listedSame assistance listing 93.837 as 472 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.837December 4, 2026Not listedSame assistance listing 93.837 as 472 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.837January 5, 2027Not listedSame assistance listing 93.837 as 472 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.837January 5, 2027Not listedSame assistance listing 93.837 as 472 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.837January 7, 2027$375,000Same assistance listing 93.837 as 472 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.837January 7, 2027Not listedSame assistance listing 93.837 as 472 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)PAR-25-025NIH93.837February 3, 2027$1.5 millionSame assistance listing 93.837 as 472 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)PAR-25-026NIH93.837February 3, 2027Not listedSame assistance listing 93.837 as 472 awards here
Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)PAR-27-125NIH93.837February 16, 2027Not listedSame assistance listing 93.837 as 472 awards here
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)RFA-DK-27-108NIH93.837March 10, 2027$500,000Same assistance listing 93.837 as 472 awards here
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)PAR-25-032NIH93.837March 16, 2027Not listedSame assistance listing 93.837 as 472 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.