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Data / Research funding / Colorectal Cancer

Colorectal Cancer: 698 NIH awards ($1.1B) to 195 organizations

698 NIH awards ($1.1B) in the NIH spending category Colorectal Cancer, to 195 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 698 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Mayo Clinic Comprehensive Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$29,249,641April 25, 1997August 31, 2030WILLMAN, CHERYL LYNNreporter.nih.gov
Environmental triggers of early-onset colorectal cancer: interactions between microplastics and pks+ E coli in early-life gut colonizationNIHNational Cancer Institute2021 to 2025$22,669,275August 1, 1997July 31, 2026TUVESON, DAVID Areporter.nih.gov
A Follow-up Study for Causes of Cancer in Black WomenNIHNational Cancer Institute2021 to 2025$11,271,706September 21, 2012August 31, 2027PALMER, JULIE Rreporter.nih.gov
Determining the mechanism of pks+ E.coli-associated carcinogenesis in early onset colorectal cancer.NIHNational Cancer Institute2022 to 2025$9,558,240September 20, 2022August 31, 2027O'REILLY, EILEEN MARYreporter.nih.gov
Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyNIHNational Cancer Institute2021 to 2025$9,251,154September 19, 2016August 31, 2026ULRICH, CORNELIA Mreporter.nih.gov
Colon Cancer Family Registry CohortNIHNational Cancer Institute2021 to 2025$8,978,119May 1, 2013April 30, 2028JENKINS, MARK Areporter.nih.gov
Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeNIHNational Cancer Institute2022 to 2025$7,696,898September 20, 2022August 31, 2027GRADY, WILLIAM MALLORYreporter.nih.gov
Early Phase Clinical Cancer Prevention ConsortiumNIHNational Cancer Institute2021 to 2025$7,613,555July 7, 2020July 31, 2031SCHUETZE, SCOTT MICHAELreporter.nih.gov
Northwestern Cancer Prevention ConsortiumNIHNational Cancer Institute2021 to 2025$7,062,222September 3, 2019July 31, 2031KHAN, SEEMA AHSANreporter.nih.gov
iCAN PREVENT: MD Anderson International Cancer Prevention Clinical Trials ConsortiumNIHNational Cancer Institute2021 to 2025$7,046,172August 15, 2019July 31, 2031VILAR SANCHEZ, EDUARDOreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,882,445September 29, 2025September 28, 2026WACTAWSKI-WENDE, JEANreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$6,534,889September 29, 2025September 28, 2026STEFANICK, MARCIAreporter.nih.gov
Decoding mechanisms underlying metabolic dysregulation in obesity and digestive cancer riskNIHNational Cancer Institute2022 to 2025$6,443,697September 20, 2022August 31, 2027TOBIAS, DEIRDRE KAYreporter.nih.gov
BASE TITLE: PREVENT PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY AND INTERMEDIATE ENDPOINT BIOMAKERSTASK ORDER TITLE: VACCINES AGAINST FUSOBACTERIUM FOR FAP-AND LYNCH SYNDROME-ASSOCIANIHNational Cancer Institute2022 to 2024$6,227,249June 15, 2022May 15, 2025CLAPPER, MARGIE L.reporter.nih.gov
The role of stem cells and the microenvironment in gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$5,569,272January 7, 2016August 31, 2030WANG, TIMOTHY CRAGINreporter.nih.gov
Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancerNIHNational Cancer Institute2021 to 2025$5,241,422July 21, 2020June 30, 2027KANNEGANTI, THIRUMALA-DEVIreporter.nih.gov
Comparative Modeling of Effective Policies for Colorectal Cancer ControlNIHNational Cancer Institute2021 to 2025$5,238,594July 1, 2025August 31, 2026ZAUBER, ANN GRAHAMreporter.nih.gov
A Multimodal 3D Atlas of Colorectal Cancer Across Ages of OnsetNIHNational Cancer Institute2024 to 2025$5,159,940September 1, 2024August 31, 2029LAU, KEN Sreporter.nih.gov
Molecular Mechanism of Mammalian DNA Excision Repair and the Circadian ClockNIHNational Institute of General Medical Sciences2021 to 2025$5,040,955April 1, 2016August 31, 2027SANCAR, AZIZreporter.nih.gov
Utility of Random Biopsies in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$5,031,513July 1, 2024June 30, 2029LEWIS, JAMES Dreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$5,000,825September 29, 2025September 28, 2026JACKSON, REBECCAreporter.nih.gov
Dose-response of aerobic training during total neoadjuvant therapy for locally advanced rectal cancerNIHNational Cancer Institute2022 to 2025$4,937,681May 6, 2022April 30, 2027SCOTT, JESSICAreporter.nih.gov
Precision Prevention Research ProgramNIHNational Cancer Institute2021 to 2025$4,849,798September 1, 2020August 31, 2027CHAN, ANDREW Treporter.nih.gov
Great Lakes New England Clinical Validation CenterNIHNational Cancer Institute2022 to 2025$4,820,800May 15, 2000August 31, 2027RICCIARDIELLO, LUIGIreporter.nih.gov
Effects of Time-restricted Eating versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers among Adults with ObesityNIHNational Cancer Institute2021 to 2025$4,635,563September 1, 2021August 31, 2027TUSSING-HUMPHREYS, LISAreporter.nih.gov
Early to Late Events in Colorectal Neoplasia: Basic Biology to Clinical ImplementationNIHNational Cancer Institute2021 to 2025$4,608,771April 1, 2017July 31, 2031COFFEY, ROBERT J.reporter.nih.gov
Intracellular Innate Immune Receptors in Cancer Suppression and ImmunotherapyNIHNational Cancer Institute2021 to 2025$4,541,273September 17, 2019August 31, 2026TING, JENNY Preporter.nih.gov
Support for the Central Data Collection Center (CDCC)NIHNational Cancer Institute2021 to 2025$4,460,745February 27, 2021February 26, 2025MATHEW, SUNITHAreporter.nih.gov
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A2NIHNational Heart, Lung, and Blood Institute2021 to 2025$4,249,024September 29, 2025September 28, 2026VITOLINS, MARAreporter.nih.gov
Leveraging Omics and Electronic Health Records Data to study Colorectal Adenoma genetics and Drug RepurposingNIHNational Cancer Institute2025$4,174,595September 10, 2025August 31, 2029GUO, XINGYIreporter.nih.gov
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and ModeratorsNIHNational Cancer Institute2021 to 2025$4,123,295June 15, 2021August 31, 2026FIGUEIREDO, JANE C.reporter.nih.gov
IL-10NanoCap® for Therapy of Familial Adenomatous PolyposisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,969,244March 7, 2019March 31, 2026AUCI, DOMINICKreporter.nih.gov
Ceramides as novel drivers of metabolic dysfunction and colorectal cancerNIHNational Cancer Institute2022 to 2025$3,957,452September 2, 2022August 31, 2027PLAYDON, MARY CHRISTINEreporter.nih.gov
GEMS: Genomic approach to connecting Elevated germline Mutation rates with male infertility and Somatic healthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,803,952September 1, 2021May 31, 2027HOTALING, JAMESreporter.nih.gov
Columbus NCORP RFA-CA-18-016NIHNational Cancer Institute2021 to 2025$3,771,688August 1, 2014July 31, 2026RAJAGOPALAN, MALOLAN Sreporter.nih.gov
Optimization of a remote intervention to improve nutrition and physical activity in colorectal cancer survivorsNIHNational Cancer Institute2021 to 2025$3,771,145December 10, 2020November 30, 2025VAN BLARIGAN, ERIN LYNNreporter.nih.gov
Rational Integration of Polygenic Risk Scores (RIPS)NIHNational Human Genome Research Institute2022 to 2025$3,737,256March 10, 2022February 28, 2027PETERSON, JOSEPH F.reporter.nih.gov
Blood-Based Testing for Advanced AdenomaNIHNational Cancer Institute2022 to 2025$3,665,539September 12, 2022February 29, 2028SCHOEN, ROBERT E.reporter.nih.gov
Effects of inflammaging on intestinal epithelial cells and aspirin chemoprevention.NIHNational Cancer Institute2021 to 2025$3,654,173April 5, 2021March 31, 2027CHAN, ANDREW Treporter.nih.gov
Role of the Epitranscriptome in CancerNIHNational Cancer Institute2021 to 2024$3,597,010August 1, 2019November 30, 2024GREGORY, RICHARD I.reporter.nih.gov
Effectiveness and implementation of a health system intervention to improve quality of cancer care for rural, underserved patientsNIHNational Cancer Institute2021 to 2025$3,568,895April 1, 2021March 31, 2027CHARLTON, MARY E.reporter.nih.gov
A Transdisciplinary Approach to Investigating Metabolic Dysregulation in Obese Parent and Child Dyads and Risk of Colorectal CancerNIHNational Cancer Institute2022 to 2025$3,558,479August 16, 2022July 31, 2028HEBERT, JAMES Rreporter.nih.gov
Variation in tumor-associated immune profiles and colorectal cancer outcomesNIHNational Cancer Institute2021 to 2025$3,497,316September 15, 2021August 31, 2027SCHMIT, STEPHANIE L.reporter.nih.gov
A Phase 1-2 clinical program for the teatment of Microsatellite Stable Colorectal Cancer with the combination of SR-8541A, Botensilimab, and BalstilimabNIHNational Cancer Institute2022 to 2025$3,457,194August 14, 2025July 31, 2028KAADIGE, MOHAN RAOreporter.nih.gov
Chemical tools for developmental biologyNIHNational Institute of General Medical Sciences2021 to 2025$3,426,216April 1, 2018June 30, 2028CHEN, JAMES Kreporter.nih.gov
Optimizing Lung Cancer Screening in Cancer SurvivorsNIHNational Cancer Institute2021 to 2025$3,415,788July 15, 2021June 30, 2027WISNIVESKY, JUAN Preporter.nih.gov
Developing and Testing a Digital Toolkit to Improve Colorectal Cancer Screening Rates in Federally Qualified Health CentersNIHNational Cancer Institute2021 to 2025$3,348,072April 1, 2021March 31, 2027MILLER, SARAH Jreporter.nih.gov
Cancer Immune-Interception for Lynch SyndromeNIHNational Cancer Institute2021 to 2025$3,326,163September 21, 2021August 31, 2026VILAR SANCHEZ, EDUARDOreporter.nih.gov
Genetic and Molecular Dissection of Wnt Pathway ActivationNIHNational Institute of General Medical Sciences2021 to 2025$3,246,880June 1, 2020July 31, 2030AHMED, YASMATHreporter.nih.gov
Self-Management to Optimize Survivorship Care and Outcomes in Lung and Colorectal CancerNIHNational Cancer Institute2021 to 2024$3,217,584April 2, 2020March 31, 2026SUN, VIRGINIA CHIH-YIreporter.nih.gov
Active Disposable Cap for Endoscope Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile PolypsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$3,206,138August 7, 2018August 31, 2025MULVIHILL, MAUREEN L.reporter.nih.gov
Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesNIHNational Cancer Institute2021 to 2025$3,190,411April 5, 2021March 31, 2027SPIEGEL, BRENNANreporter.nih.gov
Adipose tissue-colorectal tumor cross-talk: new targets for breaking the obesity-cancer linkNIHNational Cancer Institute2021 to 2025$3,159,289September 23, 2021August 31, 2026ULRICH, CORNELIA Mreporter.nih.gov
Mechanistic understanding of the lifecycle of a circulating hybrid cellNIHNational Cancer Institute2021 to 2025$3,151,928June 1, 2021May 31, 2027WONG, MELISSA H.reporter.nih.gov
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer RiskNIHNational Cancer Institute2021 to 2025$3,149,705January 15, 2021December 31, 2026FITZGIBBON, MARIAN L.reporter.nih.gov
Engineering Native E. coli to Detect, Report, and Treat Colorectal CancerNIHNational Cancer Institute2021 to 2025$3,135,340September 21, 2021August 31, 2026ZARRINPAR, AMIRreporter.nih.gov
Microbiota, Metabolites, and Colon NeoplasiaNIHNational Cancer Institute2021 to 2025$3,124,761May 1, 2021April 30, 2027ROSENBERG, DANIEL WILLIAMreporter.nih.gov
Structural and functional studies of colibactinNIHNational Cancer Institute2021 to 2025$3,124,458December 11, 2017February 29, 2028HERZON, SETH B.reporter.nih.gov
Innate lymphoid cell regulation of the host-microbiota interactions in cancerNIHNational Cancer Institute2022 to 2025$3,122,275September 20, 2022August 31, 2027SONNENBERG, GREGORY Freporter.nih.gov
SPHERE (Survivorship Plan Health Record) Implementation TrialNIHNational Cancer Institute2021 to 2025$3,117,615June 1, 2021May 31, 2027HAGGSTROM, DAVID ANDREWreporter.nih.gov
Characterizing the Risk of Chemotherapy Side Effects Based on Epigenetic Age and Modification by Resistance Training InterventionNIHNational Cancer Institute2021 to 2025$3,091,560September 8, 2021August 31, 2027BINDER, ALEXANDRA MARGARET LYNNreporter.nih.gov
Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogenNIHNational Cancer Institute2021 to 2025$3,068,738September 13, 2021August 31, 2027KHAZAIE, KHASHAYARSHAreporter.nih.gov
Integrative single cell analyses of inflammation-derived circulating hybrid cells to identify aggressive diseaseNIHNational Cancer Institute2021 to 2025$3,044,035April 1, 2021March 31, 2027WONG, MELISSA H.reporter.nih.gov
Therapeutic Targeting Mitochondrial C1 MetabolismNIHNational Cancer Institute2021 to 2025$3,043,890January 1, 2021December 31, 2026MATHERLY, LARRY Hreporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
CARES-REACH (Colorectal Cancer Awareness, Research, Education and Screening-Rural Expansion, Access and Capacity for Health)NIHNational Cancer Institute2021 to 2024$3,016,341April 1, 2020March 31, 2026GWEDE, CLEMENT K.reporter.nih.gov
Regulating cell fate and shaping the body plan during morphogenesis and their alteration during oncogenesisNIHNational Institute of General Medical Sciences2021 to 2025$3,000,444July 1, 2016August 31, 2026PEIFER, MARK A.reporter.nih.gov
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon CancerNIHNational Cancer Institute2022 to 2024$2,997,017June 3, 2022February 28, 2025BROWN, JUSTIN Creporter.nih.gov
Bacterial biosensors for the prevention of gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$2,993,830May 18, 2020April 30, 2029HASTY, JEFF Mreporter.nih.gov
The role of RAMS11 in colorectal cancer progression and treatment resistanceNIHNational Cancer Institute2021 to 2025$2,937,715August 10, 2021July 31, 2026MAHER, CHRISTOPHER Areporter.nih.gov
Behavioral Economic Approaches for Population-based Colorectal Cancer ScreeningNIHNational Cancer Institute2022 to 2025$2,932,568December 17, 2021November 30, 2026MEHTA, SHIVAN JATINreporter.nih.gov
The EPICS (Engaging Primary care in Cancer Survivorship) study: A trial of novel models of care for cancer survivorsNIHNational Cancer Institute2021 to 2024$2,922,559June 1, 2020September 30, 2025HAHN, ERIN ELIZABETHreporter.nih.gov
Innate Immune Mechanisms Contributing to Cancer Growth in ObesityNIHNational Cancer Institute2021 to 2025$2,914,829July 1, 2021June 30, 2026ENGLEMAN, EDGAR G.reporter.nih.gov
Non-invasive imaging of the anti-tumor immune responseNIHNational Cancer Institute2021 to 2025$2,904,564December 14, 2020November 30, 2026PISHESHA, NOVALIAreporter.nih.gov
Tumor selective inhibition of the WNT pathwayNIHNational Cancer Institute2022 to 2025$2,875,859September 22, 2022August 31, 2027DOW, LUKAS EDWARDreporter.nih.gov
Understanding and Harnessing Microbial Reprogramming to Combat Carcinogenic Colibactin in Colorectal CancerNIHNational Cancer Institute2025$2,864,671September 10, 2025August 31, 2029LI, JIAHEreporter.nih.gov
Interdisciplinary Epidemiologic Consortium to Investigate T-cell Response in Colorectal CancerNIHNational Cancer Institute2021 to 2025$2,822,799May 1, 2020October 31, 2026PETERS, ULRIKEreporter.nih.gov
Overcoming adaptive feedback resistance to KRAS inhibition in colorectal cancerNIHNational Cancer Institute2022 to 2025$2,815,123April 1, 2022March 31, 2027CORCORAN, RYAN BRUCEreporter.nih.gov
Rural Community Support for ColonoscopyNIHNational Cancer Institute2021 to 2025$2,814,878March 8, 2021February 28, 2027COLE, ALLISONreporter.nih.gov
New Epidemiologic Methods for Reducing Measurement Error and Misclassification Bias in Cancer EpidemiologyNIHNational Cancer Institute2023 to 2025$2,790,776September 21, 2023August 31, 2027WANG, MOLINreporter.nih.gov
DNA Adduct Detection and Repair in Mammalian CellsNIHNational Institute of Environmental Health Sciences2021 to 2025$2,783,115September 17, 2021June 30, 2027SANCAR, AZIZreporter.nih.gov
Treating colon cancer by regulating intestinal immunity through microbial metabolismNIHNational Cancer Institute2021 to 2025$2,772,249June 1, 2021May 31, 2027ARPAIA, NICHOLASreporter.nih.gov
Multi-cancer early detection using cell-free DNA methylome analysisNIHNational Cancer Institute2023 to 2025$2,757,500September 19, 2023August 31, 2028ZHOU, XIANGHONG JASMINEreporter.nih.gov
Community Partnership for Telehealth Solutions to Counter Misinformation and Achieve Equity (PRIME)NIHNational Institute on Minority Health and Health Disparities2022 to 2024$2,752,440September 18, 2022May 2, 2024PETRIK, AMANDA F.reporter.nih.gov
Integration of epidemiology, pathology, immunology and outcomes in colorectal cancerNIHNational Cancer Institute2022 to 2025$2,735,518September 22, 2022August 31, 2027GRUBER, STEPHEN Breporter.nih.gov
AND-gated Synthetic Biomarkers for Early Detection of Liver MetastasisNIHNational Cancer Institute2021 to 2025$2,734,586September 23, 2021August 31, 2027KWONG, GABRIEL Areporter.nih.gov
Obesity, sedentary behaviors, and diet quality for prevention and early detection of early-onset colorectal neoplasiaNIHNational Cancer Institute2021 to 2025$2,729,669July 1, 2020June 30, 2027CAO, YINreporter.nih.gov
The ASPIRES Study: Activating Cancer Survivors and their Primary Care Providers to Increase Colorectal Cancer ScreeningNIHNational Cancer Institute2021 to 2025$2,725,531March 1, 2021March 31, 2025HENDERSON, TARA OLIVEreporter.nih.gov
Cancer Immune-Interception in a Spontaneous Non-Human Primate Model of Lynch SyndromeNIHNational Cancer Institute2022 to 2025$2,721,586August 22, 2022July 31, 2027VILAR SANCHEZ, EDUARDOreporter.nih.gov
Association between pre-diagnosis hepatic fat infiltration and risk of liver metastasis and mortality in a large cohort of stage I-III colorectal cancer survivorsNIHNational Cancer Institute2022 to 2025$2,716,606September 23, 2022August 31, 2027GIOVANNUCCI, EDWARDreporter.nih.gov
Understanding the Contribution of Colorectal Cancer Tumor Characteristics to Disparities in Colorectal Cancer SurvivalNIHNational Cancer Institute2021 to 2025$2,714,017July 15, 2021June 30, 2027WARREN ANDERSEN, SHANEDAreporter.nih.gov
Time-dependent and bidirectional effect of oxidative stress - a missing piece of the free radical theory of cancer and its potential implicationsNIHNational Cancer Institute2021 to 2025$2,701,769December 1, 2019November 30, 2026YANG, GONGreporter.nih.gov
Multiscale Modeling to Optimize Inhibition of Oncogenic ERK Pathway SignalingNIHNational Cancer Institute2021 to 2024$2,681,014February 7, 2020January 31, 2025LEMMON, MARK Areporter.nih.gov
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated CarcinogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,674,708March 31, 2021February 28, 2026WILSON, KEITH T.reporter.nih.gov
Preclinical Development of First-in-Class GSTO1 Degraders for Colorectal CancerNIHNational Cancer Institute2022 to 2025$2,673,041August 2, 2022July 31, 2027NEAMATI, NOURIreporter.nih.gov
Fiber-rich Foods to Treat Obesity and Prevent Colon CancerNIHNational Cancer Institute2021 to 2024$2,669,304July 15, 2020June 30, 2026HARTMAN, TERRYL J.reporter.nih.gov
Novel Biomarkers for Cancer-Related Fatigue: Integrating Metabolomics, Genomics and BehaviorsNIHNational Institute of Nursing Research2021 to 2024$2,663,131May 28, 2020March 31, 2025FIGUEIREDO, JANE C.reporter.nih.gov
Advancing equity in colorectal cancer genetic risk prediction through expansion of racial/ethnic minority representationNIHNational Cancer Institute2021 to 2024$2,661,057July 1, 2020June 30, 2025PETERS, ULRIKEreporter.nih.gov
An integrative omics approach to investigate gene-environment interaction in colorectal cancer riskNIHNational Cancer Institute2023 to 2025$2,659,982June 1, 2023May 31, 2028PETERS, ULRIKEreporter.nih.gov
Discovery and verification of methylated circulating tumor DNA markers for the detection of colorectal cancer in subjects under 50 years of ageNIHNational Cancer Institute2021 to 2024$2,647,966July 1, 2021June 30, 2026HITCHINS, MEGAN Preporter.nih.gov
Expansion of Tumoroid Models for Precise Treatment of the Rectal Cancer PatientNIHNational Cancer Institute2021 to 2025$2,633,017March 1, 2025June 30, 2025SMITH, JESSE JOSHUAreporter.nih.gov
Coffee and metabolites modulating the gut microbiome for improved colorectal cancer survivalNIHNational Cancer Institute2022 to 2025$2,628,801June 2, 2022May 31, 2027SONG, MINGYANGreporter.nih.gov
IMProving Adherence to Colonoscopy through Teams and Technology (IMPACTT)NIHNational Cancer Institute2022 to 2025$2,621,250May 16, 2022February 28, 2027SARKAR, URMIMALAreporter.nih.gov
Intestinal surveillance by intraepithelial lymphocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,589,419July 1, 2017April 30, 2026MUCIDA, DANIEL Sreporter.nih.gov
Investigation of FadA adhesin from Fusobacterium nucleatumNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,580,121September 10, 2020August 31, 2026HAN, YIPINGreporter.nih.gov
Personalized Provider Selection to Reduce Surgical DisparitiesNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,578,451May 19, 2022February 28, 2027KELZ, RACHELreporter.nih.gov
ALOX15 regulation of colon cancer invasiveness via PI3P-linoleic acid metabolismNIHNational Cancer Institute2022 to 2025$2,576,142January 1, 2022April 30, 2027SHUREIQI, IMADreporter.nih.gov
Kinome-guided Targeting of Cooperative Dependencies in BRAF Mutated Colorectal CancerNIHNational Cancer Institute2021 to 2025$2,574,186June 1, 2019May 31, 2029COPPE, JEAN-PHILIPPE FRANCOIS MARIEreporter.nih.gov
Unique targeting of PPARβ/δ regulation for cancer prevention and therapyNIHNational Cancer Institute2021 to 2024$2,559,468December 6, 2019November 30, 2025PETERS, JEFFREY Mreporter.nih.gov
Inhibition of the Wnt Receptor Complex by the Tumor Suppressor Adenomatous Polyposis ColiNIHNational Cancer Institute2021 to 2024$2,543,570July 15, 2020June 30, 2026AHMED, YASMATHreporter.nih.gov
Circadian Clock and Myc-dependent Regulation of Cellular TransformationNIHNational Cancer Institute2022 to 2025$2,542,136January 1, 2022December 31, 2026MASRI, SELMAreporter.nih.gov
A Statistical Physics Framework for Understanding the Role of Repeat RNA in Tumor ImmunityNIHNational Cancer Institute2021 to 2024$2,539,571September 15, 2020August 31, 2025GREENBAUM, BENJAMINreporter.nih.gov
SUMO Modification and Cancer TherapyNIHNational Cancer Institute2021 to 2025$2,526,679May 1, 2021April 30, 2026CHEN, YUANreporter.nih.gov
Design and characterization of bacterial population dynamics in solid tumor modelsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,515,679August 1, 2021April 30, 2025HASTY, JEFF Mreporter.nih.gov
Role of Erbb3 kinase activity in colorectal tumorigenesis.NIHNational Cancer Institute2021 to 2025$2,509,394February 9, 2021January 31, 2026WANG, ZHENGHEreporter.nih.gov
Fluorescence guided nerve sparing during colorectal cancer surgery using local application of a near infrared nerve fluorophoreNIHNational Cancer Institute2025$2,491,138August 15, 2025July 31, 2029GIBBS, SUMMER LYNNEreporter.nih.gov
Leveraging Novel Randomized Clinical Trials of Vitamin D Supplementation in Patients with Colorectal Cancer: Impact on Survival and Anti-Tumor ImmunityNIHNational Cancer Institute2021 to 2025$2,477,583March 15, 2017June 30, 2027NG, KIMMIEreporter.nih.gov
Mouse models of Kras-mutant colorectal cancerNIHNational Cancer Institute2021 to 2024$2,463,211July 1, 2020June 30, 2026HAIGIS, KEVINreporter.nih.gov
Tumor Organoid-Mediated Drug Testing and Clonality Analysis in Peritoneal Surface Disease of Intestinal OriginNIHNational Cancer Institute2021 to 2025$2,463,080March 1, 2021February 28, 2027VOTANOPOULOS, KONSTANTINOSreporter.nih.gov
Deconstructing and targeting aneuploidy in human cancer - Resubmission - 1NIHNational Cancer Institute2021 to 2025$2,458,661April 1, 2021March 31, 2026DAVOLI, TERESAreporter.nih.gov
Developing novel bispecific antibodies for cancer treatmentNIHNational Cancer Institute2021 to 2025$2,437,200July 1, 2021June 30, 2027FAN, ZHENreporter.nih.gov
Polymerase epsilon-based mouse and derived organoid models of intestinal cancerNIHNational Cancer Institute2022 to 2025$2,435,094September 15, 2022August 31, 2027CASTRILLON, DIEGO Hreporter.nih.gov
Role of immune regulation in colorectal cancer chemotherapeutic responseNIHNational Cancer Institute2021 to 2025$2,422,671September 1, 2021August 31, 2026LU, JUNreporter.nih.gov
Advancing Access in Cancer Care: Investigating Health-Related Social Needs and Colonoscopy Follow-Up Among FQHC PatientsNIHNational Cancer Institute2023 to 2025$2,422,382May 4, 2023April 30, 2028DOUBENI, CHYKE ABADAMAreporter.nih.gov
Upgrading rigor and efficiency of germline cancer gene variant classification for the 2020sNIHNational Cancer Institute2022 to 2025$2,422,203March 1, 2022January 31, 2027TAVTIGIAN, SEAN VAHRAMreporter.nih.gov
Designing a Plan of Action for Better Access and Quality of Surgery for African-Americans with Gastrointestinal Cancers in the Deep SouthNIHNational Institute on Minority Health and Health Disparities2021 to 2024$2,406,877June 15, 2020January 31, 2026PISU, MARIAreporter.nih.gov
SIRPant Technology for anti-Cancer ImmunityNIHNational Cancer Institute2021 to 2024$2,399,999September 22, 2021July 31, 2025MCCURLEY, NATHANAELreporter.nih.gov
The Gut Microbiome, Lifestyle, and Colorectal NeoplasiaNIHNational Cancer Institute2022 to 2025$2,397,399May 1, 2022April 30, 2027SONG, MINGYANGreporter.nih.gov
Optical imaging to predict cell-level genetic heterogeneity and treatment sensitivity in colorectal cancerNIHNational Cancer Institute2021 to 2024$2,396,849June 8, 2018May 31, 2025DEMING, DUSTIN Areporter.nih.gov
Time-varying relationships between built environment factors, colon and rectum cancer prognosis, and survivalNIHNational Cancer Institute2022 to 2025$2,370,003May 1, 2022April 30, 2027PLASCAK, JESSE JOHNreporter.nih.gov
NOT-CA-24-111 Improving Strategies for Cancer Reduction through Early-detection and ENgagement (I-SCREEN)NIHNational Cancer Institute2024 to 2025$2,357,813February 14, 2024December 31, 2027COOK, LINDA Sreporter.nih.gov
Engineering immunotherapeutic probiotics to mitigate irAENIHNational Cancer Institute2021 to 2024$2,351,179January 21, 2020December 31, 2024DANINO, TALreporter.nih.gov
A cloud-based digital health navigation program for colorectal cancer screeningNIHNational Cancer Institute2023 to 2025$2,350,065April 1, 2023June 30, 2027MILLER, DAVID Preporter.nih.gov
Functional optical imaging for rapid, label-free predictions of treatment response and clonal evolution in patient-derived cancer organoidsNIHNational Cancer Institute2023 to 2025$2,348,049April 1, 2023March 31, 2028SKALA, MELISSA CAROLINEreporter.nih.gov
MyGI Diet for Colorectal Cancer PreventionNIHNational Cancer Institute2021 to 2025$2,345,455July 1, 2021June 30, 2027BUIS, LORRAINE Rreporter.nih.gov
Advancing Precision Oncology in a Humanized, Fully Autologous Mouse ModelNIHNational Cancer Institute2021 to 2024$2,342,069March 1, 2020February 28, 2026FIELDS, RYAN Creporter.nih.gov
Real time colon histopathology by infrared spectroscopic imagingNIHNational Cancer Institute2021 to 2025$2,305,182July 1, 2021June 30, 2027BHARGAVA, ROHITreporter.nih.gov
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal CryptsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,304,272February 15, 2022January 31, 2026KLEIN, OPHIR Dreporter.nih.gov
Optimizing colorectal cancer prevention: a multi-disciplinary, population-based investigation of serrated polyps using risk prediction and modelingNIHNational Cancer Institute2021 to 2024$2,300,681July 1, 2020June 30, 2025BUTTERLY, LYNN Freporter.nih.gov
Metabolism of cancer chemotherapeutics by the human gut microbiomeNIHNational Cancer Institute2023 to 2025$2,300,078September 1, 2023August 31, 2028TURNBAUGH, PETER JAMESreporter.nih.gov
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care (PRIME)NIHNational Institute on Minority Health and Health Disparities2024 to 2025$2,298,376September 18, 2022April 30, 2027CORONADO, GLORIA D.reporter.nih.gov
Sirtuins and CancerNIHNational Cancer Institute2022 to 2025$2,289,538June 15, 2022May 31, 2027HAIGIS, MARCIAreporter.nih.gov
HFH-MSU CSRN ACCrual Enrollment and Screening SiteNIHNational Cancer Institute2024 to 2025$2,289,116March 7, 2025December 31, 2027NESLUND-DUDAS, CHRISTINE MARIEreporter.nih.gov
Coordination of Innate and Adaptive Immunity in Intestinal Barrier DefenseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,271,848March 1, 2022February 28, 2027WEAVER, CASEY Treporter.nih.gov
Pathogenesis of Early Onset Colorectal Cancer: Microbiome Contributions and MechanismsNIHNational Cancer Institute2021 to 2025$2,266,043September 23, 2021August 31, 2026SEARS, CYNTHIAreporter.nih.gov
A cancer-derived truncating mutation in disease penetrance and progression of MSI CRCNIHNational Cancer Institute2021 to 2024$2,262,153August 6, 2020November 30, 2025LIANG, CHENGYUreporter.nih.gov
The selective advantage of mismatch repair loss in colonic stem cellsNIHNational Cancer Institute2021 to 2025$2,253,508April 1, 2021March 31, 2027HEINEN, CHRISTOPHER D.reporter.nih.gov
Molecular mechanisms driving mesenchymal colorectal cancerNIHNational Cancer Institute2021 to 2025$2,244,982March 17, 2021February 28, 2026MOSCAT, JORGEreporter.nih.gov
Role of Receptor Tyrosine Kinase cross-talk in colorectal cancerNIHNational Cancer Institute2021 to 2025$2,240,946May 12, 2021April 30, 2027SINGH, BHUMINDERreporter.nih.gov
PROSPECT-Global Consortium and Risk Factor DiscoveryNIHNational Cancer Institute2024 to 2025$2,222,328May 1, 2024April 30, 2026CAO, YINreporter.nih.gov
Colorectal carcinogenesis and Fusobacterium nucleatum: oncomicrobe, oncometabolites, and oncoimmunologyNIHNational Cancer Institute2021 to 2025$2,221,814March 18, 2011July 31, 2027GARRETT, WENDY S.reporter.nih.gov
Ethnicity and Nativity in Cancer - Latino & Asian Enclaves: The ENCLAVE StudyNIHNational Cancer Institute2021 to 2024$2,219,992April 1, 2020March 31, 2026SHARIFF-MARCO, SALMAreporter.nih.gov
Ubiquitination, Intestinal Homeostasis and CancerNIHNational Cancer Institute2022 to 2025$2,211,716September 1, 2022August 31, 2027MA, AVERIL Ireporter.nih.gov
Strengthening gut barrier integrity with beneficial microbes to increase lifespan and healthspanNIHNational Institute on Aging2022 to 2025$2,197,864September 15, 2021May 31, 2027CROTT, JIMMY Wreporter.nih.gov
The role of the senescent microenvironment on cancer initiating cells in the colon.NIHNational Institute on Aging2021 to 2025$2,183,637September 30, 2021August 31, 2026GRADY, WILLIAM MALLORYreporter.nih.gov
Mechanisms of Dynamic Transcriptional Reprogramming in Metastasis Stem CellsNIHNational Cancer Institute2022 to 2025$2,177,395March 1, 2022January 31, 2027GANESH, KARUNAreporter.nih.gov
Role of PTPRT in colon cancer progression and metastasisNIHNational Cancer Institute2022 to 2025$2,174,026August 24, 2022July 31, 2027WANG, ZHENGHEreporter.nih.gov
Uncovering colorectal cancer etiology and biology by integrating proteomics with other omics dataNIHNational Cancer Institute2023 to 2025$2,171,240April 11, 2023March 31, 2028GUO, XINGYIreporter.nih.gov
Inactivation of MSH3 in Colorectal Cancer and RaceNIHNational Cancer Institute2022 to 2025$2,166,564August 1, 2021July 31, 2026CARETHERS, JOHN Mreporter.nih.gov
Population-based assessment of patient-reported outcomes in adults living with metastatic colorectal cancerNIHNational Cancer Institute2023 to 2025$2,151,172September 19, 2023August 31, 2028POTOSKY, ARNOLD Lreporter.nih.gov
Characterization and modeling of m6A RNA methylation in cancerNIHNational Cancer Institute2021 to 2024$2,150,624September 1, 2020May 31, 2026LIANG, HANreporter.nih.gov
Aggressive colorectal cancer subtypes and social disadvantage in a racially diverse cohortNIHNational Cancer Institute2022 to 2025$2,146,832June 1, 2021December 31, 2026ROZEK, LAURAreporter.nih.gov
Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signalingNIHNational Cancer Institute2021 to 2024$2,143,591September 3, 2020May 31, 2026CHAPKIN, ROBERT STEPHENreporter.nih.gov
Discovery of small molecule inhibitors for protein N-terminal acetyltransferase DNIHNational Cancer Institute2022 to 2025$2,138,837December 1, 2021November 30, 2026HUANG, RONGreporter.nih.gov
Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancersNIHNational Cancer Institute2021 to 2025$2,137,708July 1, 2025June 30, 2027BRYANT, KIRSTEN Lreporter.nih.gov
Targeting colorectal cancer stem cells with ALDH1B1 antagonistsNIHNational Cancer Institute2021 to 2025$2,133,438June 1, 2021May 31, 2026CHEN, JAMES Kreporter.nih.gov
Gut microbiota-related mechanisms that impact colorectal cancer risk after bariatric surgeryNIHNational Cancer Institute2023 to 2025$2,129,873September 7, 2023August 31, 2028YU, DANXIAreporter.nih.gov
Biomaterials for modulating the gut microbiome for immune activationNIHNational Cancer Institute2022 to 2025$2,127,257May 1, 2022April 30, 2027MOON, JAMES J.reporter.nih.gov
Development of multifunctional drug and immune modulator delivery nanoparticles for the treatment of cancer patients with comorbid atherosclerosisNIHNational Cancer Institute2021 to 2025$2,122,501February 1, 2021January 31, 2026YANG, LILYreporter.nih.gov
Health and Financial Costs of Unequal Care: Colorectal Cancer as a Case StudyNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,119,031September 23, 2023March 31, 2028RUTTER, CAROLYN Mreporter.nih.gov
Exercise as Interception Therapy in Primary High Risk CancerNIHNational Cancer Institute2021 to 2024$2,107,239September 3, 2020June 30, 2026JONES, LEE Wreporter.nih.gov
TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumorsNIHNational Cancer Institute2023 to 2025$2,103,321June 9, 2023May 31, 2028BRACKETT, CRAIG M.reporter.nih.gov
Molecular and functional investigation of the role of CD1 in gamma delta T cell surveillanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,098,612September 22, 2020August 31, 2025ADAMS, ERIN JUNEreporter.nih.gov
Folic Acid Supplementation and Colitis-associated Colon CarcinogenesisNIHNational Cancer Institute2022 to 2025$2,082,906May 11, 2022April 30, 2027CLAPPER, MARGIE L.reporter.nih.gov
Understanding intrinsic resistance to direct KRAS inhibition in colorectal cancersNIHNational Cancer Institute2022 to 2025$2,067,058January 1, 2022December 31, 2026GORDAN, JOHN Dreporter.nih.gov
Deep molecular and cellular profiling of colorectal cancer tumor and immune microenvironment in Alaska Native peopleNIHNational Cancer Institute2023 to 2025$2,066,819May 25, 2023April 30, 2028HUYGHE, JEROEN Rreporter.nih.gov
Biomarkers, mechanisms and modulation of oxidative stress associated risk factors in carcinogenesisNIHOffice of the Director, National Institutes of Health2022 to 2025$2,065,432September 14, 2022December 31, 2025LI, YUN ROSEreporter.nih.gov
Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,053,464March 24, 2021February 28, 2027POOJARY, VENUPRASAD Kreporter.nih.gov
Investigating a master regulator of large intestine stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,038,576August 1, 2021July 31, 2025RAFII, SHAHINreporter.nih.gov
Circadian Clock Disruption and Colorectal CancerNIHNational Cancer Institute2021 to 2025$2,037,646March 1, 2020July 31, 2030MASRI, SELMAreporter.nih.gov
Mitochondria-to-Nucleus Signaling in Colorectal CancerNIHNational Cancer Institute2021 to 2024$2,035,169December 1, 2019November 30, 2024SHADEL, GERALDreporter.nih.gov
Impact of CLDN1 inhibition on chemoresistance and metastasis of colon cancerNIHNational Cancer Institute2021 to 2024$2,033,632February 12, 2021January 31, 2026DHAWAN, PUNITAreporter.nih.gov
Personalizing Post-Polypectomy Surveillance for Colorectal Cancer PreventionNIHNational Cancer Institute2023 to 2025$2,027,204September 19, 2023August 31, 2028LEE, JEFFREY KUANG ZOUreporter.nih.gov
UNCOVER: underlying novel causes of onset of very early cancer researchNIHNational Cancer Institute2021 to 2025$2,020,293September 6, 2021August 31, 2027YANG, WANreporter.nih.gov
Addressing the Biology of Health Disparities by Targeting Geographical Ancestry-driven Variants of ImmunityNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,010,639September 20, 2021May 31, 2027KIMBRO, KEVIN SEANreporter.nih.gov
Analyzing the Hypersensitivity of MMR-deficient Colorectal Cancers to mTOR Inhibition and the Response of Cancer Stem CellsNIHNational Cancer Institute2021 to 2025$2,004,798April 1, 2021March 31, 2026EDELMANN, WINFRIEDreporter.nih.gov
Small Molecule MYC Degraders as Novel Cancer Therapeutic AgentsNIHNational Cancer Institute2023 to 2024$2,000,000April 5, 2022August 31, 2025FEI, DENNIS LIANGreporter.nih.gov
Immunotherapy to deplete key Treg subsets in solid tumorsNIHNational Cancer Institute2024 to 2025$2,000,000August 13, 2024July 31, 2027SUZDAK, PETER DAVIDreporter.nih.gov
Antigen-targeted activation of Topo1 inhibitors via click chemistryNIHNational Cancer Institute2024 to 2025$1,999,929September 6, 2024August 31, 2026MEJIA ONETO, JOSE Mreporter.nih.gov
Risk stratified survivorship care pathways for early-onset colorectal cancerNIHNational Cancer Institute2023 to 2025$1,993,826March 21, 2023February 29, 2028WALLNER, LAUREN Preporter.nih.gov
Engineered Colon Cancer Tissue to Examine the Role of the Obese Microenvironment in Tumor AggressivenessNIHNational Cancer Institute2022 to 2025$1,993,201July 1, 2022June 30, 2027LIPKE, ELIZABETH Areporter.nih.gov
Topic Number 431Cancer Treatment Technologies for Low-Resource SettingsNIHNational Cancer Institute2024$1,987,032September 12, 2024September 11, 2026MONTY, NATHANreporter.nih.gov
Optimal Colorectal Cancer Surveillance Strategy for Lynch Syndrome by GenotypeNIHNational Cancer Institute2021 to 2025$1,983,781August 1, 2021July 31, 2026HUR, CHINreporter.nih.gov
Improved Treatment of Colorectal Cancer with CF10NIHNational Cancer Institute2023 to 2024$1,983,010May 1, 2023April 30, 2026GMEINER, WILLIAM H.reporter.nih.gov
Novel Targeted Anticancer Agents from Marine CyanobacteriaNIHNational Cancer Institute2021 to 2025$1,978,529March 6, 2013January 31, 2030LUESCH, HENDRIKreporter.nih.gov
Targeting immunoproteasome-mediated antigen presentation in colorectal cancer immunotherapyNIHNational Cancer Institute2022 to 2025$1,972,182January 1, 2022December 31, 2026ZHANG, XINNAreporter.nih.gov
Gasdermin E and pyroptosis in cancerNIHNational Cancer Institute2021 to 2024$1,970,899April 3, 2020March 31, 2025LIEBERMAN, JUDYreporter.nih.gov
Mechanisms of PIK3CA helical domain mutations driving colorectal tumorigenesisNIHNational Cancer Institute2021 to 2025$1,968,370August 6, 2021July 31, 2026WANG, ZHENGHEreporter.nih.gov
A Cereblon signaling network in Wnt-driven cancersNIHNational Cancer Institute2023 to 2025$1,966,061March 10, 2023February 29, 2028AHMED, YASMATHreporter.nih.gov
Wnt Pathway Regulation of Gastric Stem Cell FunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,965,318February 1, 2022January 31, 2026SAMUELSON, LINDA C.reporter.nih.gov
Multiplexed drug testing of micro-dissected tumors using a microfluidic platform with integrated electrochemical aptasensorsNIHNational Cancer Institute2023 to 2025$1,961,711April 1, 2023March 31, 2028FOLCH, ALBERTreporter.nih.gov
Diagnosis of Cancer in the Emergency Room - Explaining Persistent DisparitiesNIHNational Cancer Institute2021 to 2025$1,957,730July 1, 2021June 30, 2027THOMPSON, CAROLINE AVERYreporter.nih.gov
Rapid Adoption of Robotic Surgery: Risks, Benefits, and Unintended ConsequencesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,956,732January 21, 2022December 31, 2025DIMICK, JUSTIN BRIGHAMreporter.nih.gov
How beta-catenin expands Foxp3+RORgammat+ Pro-inflammatoryT-regulatory cells - RenewalNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,948,254July 1, 2022June 30, 2025GOUNARI, FOTINIreporter.nih.gov
REmote symptom COllection to improVE postopeRative care (RECOVER)NIHNational Institute on Minority Health and Health Disparities2023 to 2025$1,946,544July 15, 2023December 31, 2027SHARA, NAWARreporter.nih.gov
Quantitative top-down proteomics of human colorectal cancer cells and tumorsNIHNational Cancer Institute2021 to 2025$1,944,242February 10, 2021January 31, 2027SUN, LIANGLIANGreporter.nih.gov
Early response to radiotherapy and immunotherapy in rectal cancer: an integrated molecular, cellular, and spatial approachNIHNational Cancer Institute2023 to 2025$1,938,556August 1, 2023July 31, 2028AGUILERA, TODD Areporter.nih.gov
Registering Cancer Recurrences in the Georgia Cancer RegistryNIHNational Cancer Institute2021 to 2024$1,933,624February 15, 2019July 31, 2025WARD, KEVIN Creporter.nih.gov
Implementing evidence based colorectal cancer screening in rural clinicsNIHNational Cancer Institute2023 to 2025$1,922,166January 1, 2023December 31, 2027CHAMPION, VICTORIA LEEreporter.nih.gov
Therapeutic targeting of Wnt signaling in cancerNIHNational Cancer Institute2023 to 2025$1,913,719December 1, 2022November 30, 2027CHEN, CHUOreporter.nih.gov
Novel Post-surgical Incision Management Device to Prevent Ostomy ComplicationsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,909,235March 1, 2023February 28, 2027OBST, ANDREW Treporter.nih.gov
Defining the function of Complex I truncating mutations in cancerNIHNational Cancer Institute2023 to 2025$1,896,011January 1, 2023December 31, 2027REZNIK, EDUARDreporter.nih.gov
Multilevel health system intervention to increase surveillance colonoscopy for high-risk colorectal polypsNIHNational Cancer Institute2022 to 2025$1,892,563August 1, 2022November 30, 2027MAY, FOLASADE POPOOLAreporter.nih.gov
Assessing the long-term impacts of the COVID-19 pandemic on disparities in cancer screening and follow-upNIHNational Cancer Institute2021 to 2024$1,886,468July 15, 2021July 2, 2024DICKERSON, JOHN Freporter.nih.gov
Understanding the role and clinical potential of dominant immune suppressive myeloid-cell responses in human cancerNIHNational Cancer Institute2021 to 2025$1,881,297September 10, 2021August 31, 2026SCHALPER, KURT Areporter.nih.gov
Mismatch Repair and CarcinogenesisNIHNational Cancer Institute2021 to 2025$1,880,282April 1, 1995June 30, 2027FISHEL, RICHARDreporter.nih.gov
Understanding the mechanisms of iron addiction in colon cancerNIHNational Cancer Institute2021 to 2024$1,878,533July 1, 2020June 30, 2025SHAH, YATRIK Mreporter.nih.gov
The kynurenine-AHR pathway in biomass productionNIHNational Cancer Institute2021 to 2024$1,873,349March 1, 2020February 28, 2026CONACCI-SORRELL, MARALICEreporter.nih.gov
Defining the role of tumoral MHC Class I Expression in Mediating Colorectal Cancer Racial DisparitiesNIHNational Cancer Institute2023 to 2025$1,868,361August 1, 2023July 31, 2028RUBINSTEIN, MARK Preporter.nih.gov
Advancing MRI technology for early diagnosis of liver metastasesNIHNational Cancer Institute2021 to 2024$1,861,579December 1, 2019November 30, 2025ALTBACH, MARIA I.reporter.nih.gov
Long-Term Adverse Outcomes Among Rural Cancer Survivors in a Population-Based CohortNIHNational Cancer Institute2021 to 2024$1,858,613July 16, 2020June 30, 2025CAMP, NICOLA J.reporter.nih.gov
Elucidating the role of gut microbiota in colitis-associated colorectal cancerNIHNational Cancer Institute2023 to 2025$1,850,100January 1, 2023December 31, 2027CHEN, RUreporter.nih.gov
Multi-modal machine learning to guide adjuvant therapy in surgically resectable colorectal cancerNIHNational Cancer Institute2023 to 2025$1,848,386May 2, 2023April 30, 2028SHEN, JEANNEreporter.nih.gov
Control of regulatory T cells by IL-17 in colorectal cancerNIHNational Cancer Institute2021 to 2025$1,841,987June 1, 2021May 31, 2026WANG, KEPENGreporter.nih.gov
Prebiotic effect of eicosapentaenoic acid treatment for colorectal cancerNIHNational Cancer Institute2021 to 2024$1,831,134June 1, 2020June 30, 2024CHAN, ANDREW Treporter.nih.gov
Evaluating a remotely delivered, digital health CRC screening intervention among rural patients of a community health centerNIHNational Cancer Institute2023 to 2025$1,824,412August 1, 2023July 31, 2028FRERICHS, LEAH M.reporter.nih.gov
Role of the complement C3a receptor on immune and non immune intestinal barrier functions and microbiota in colorectal cancer developmentNIHNational Cancer Institute2022 to 2025$1,824,040August 1, 2022July 31, 2027GUGLIETTA, SILVIAreporter.nih.gov
The role of ACSS2 in colon cancerNIHNational Cancer Institute2022 to 2025$1,822,535April 1, 2022March 31, 2027WOTTON, DAVIDreporter.nih.gov
Epigenetic dysregulation in APC-negative colorectal cancerNIHNational Cancer Institute2021 to 2024$1,815,653August 1, 2020December 31, 2025ELLIS, NATHAN A.reporter.nih.gov
Harnessing the power of p53 with Panaxynol from American Ginseng to suppress colitis and prevent colon cancerNIHNational Cancer Institute2021 to 2024$1,813,414January 1, 2020December 31, 2024HOFSETH, LORNE Jreporter.nih.gov
Use of radioprotector in rectal cancerNIHNational Cancer Institute2022 to 2025$1,812,623April 8, 2022January 31, 2028OBERLEY-DEEGAN, REBECCA Ereporter.nih.gov
Molecular mechanisms of modular nuclease domainsNIHNational Institute of General Medical Sciences2021 to 2025$1,812,290September 15, 2021August 31, 2026MANHART, CAROL Mreporter.nih.gov
Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral originsNIHNational Cancer Institute2021 to 2024$1,811,473May 1, 2021April 30, 2025SCHMIT, STEPHANIE L.reporter.nih.gov
Mechanisms of nuclear Mcl-1 mediated chemoresistanceNIHNational Cancer Institute2021 to 2025$1,808,294December 4, 2020November 30, 2025MELENHORST, JAN Jreporter.nih.gov
Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colon CancerNIHNational Cancer Institute2022 to 2024$1,797,544June 3, 2022February 28, 2025BROWN, JUSTIN Creporter.nih.gov
The role of HIF2alpha in colon carcinogenesisNIHNational Cancer Institute2021 to 2025$1,782,443July 6, 2010June 30, 2026SHAH, YATRIK Mreporter.nih.gov
A Chemical Genetic Approach to Exploring Novel Therapeutic Space for Colorectal CancerNIHNational Cancer Institute2023 to 2025$1,782,261June 1, 2023February 28, 2026DAR, ARVINreporter.nih.gov
Targeting Tryptophan Metabolism in Rectal CancerNIHNational Cancer Institute2023 to 2025$1,780,760September 21, 2023August 31, 2028CIORBA, MATTHEW AARONreporter.nih.gov
Physiological and psychosocial aspects of reproductive health after early-onset colorectal cancerNIHNational Cancer Institute2023 to 2025$1,773,238May 11, 2023April 30, 2028HOLOWATYJ, ANDREANA NATALIEreporter.nih.gov
Safety and Efficacy Trial of the ColoSeal ICD System for the Treatment of Rectal Cancer PatientsNIHNational Cancer Institute2024 to 2025$1,767,129September 20, 2024August 31, 2026FONG, KENTON DODYANreporter.nih.gov
Bayesian Network-Based Integrative Genomics Methods for Precision MedicineNIHNational Cancer Institute2021 to 2024$1,760,765February 1, 2021January 31, 2026MORRIS, JEFFREY Sreporter.nih.gov
Allosteric inhibitors targeting oncogenic BRAF V600E dimersNIHNational Cancer Institute2021 to 2024$1,760,127December 1, 2019November 30, 2024GAVATHIOTIS, EVRIPIDISreporter.nih.gov
Immunoepigenetic targeting of MHC regulators in FAPNIHNational Cancer Institute2023 to 2025$1,755,233April 1, 2023March 31, 2028DASHWOOD, RODERICK Hreporter.nih.gov
Understanding the Mechanism of a Gut Microbial Genotoxin Involved in Colorectal CarcinogenesisNIHNational Cancer Institute2021 to 2025$1,752,081July 1, 2016January 31, 2027BALSKUS, EMILY PATRICIAreporter.nih.gov
Development of an automated, point of care DNA methylation cartridge blood test for colorectal cancer detection in LMICs- an academic-industrial partnershipNIHNational Cancer Institute2023 to 2025$1,730,278June 6, 2023May 31, 2028SUKUMAR, SARASWATIreporter.nih.gov
Personalized Risk-AdaptIve Surveillance (PRAISE) - Implications of Algorithmic BiasNIHNational Cancer Institute2021 to 2024$1,727,788September 1, 2018August 31, 2026BANSAL, AASTHAAreporter.nih.gov
Reducing Colorectal Cancer Health Disparities: An mHealth Intervention to Improve Screening among African American MenNIHNational Cancer Institute2021 to 2024$1,724,375September 11, 2019June 30, 2025LEAF, SAMANTHA L.reporter.nih.gov
Nanodelivery of FP polymers to improve treatment of metastatic colorectal cancerNIHNational Cancer Institute2023 to 2025$1,721,807July 1, 2023June 30, 2028GMEINER, WILLIAM H.reporter.nih.gov
Targeting Lipid Metabolism in Colorectal CancerNIHNational Cancer Institute2021 to 2025$1,709,510April 1, 2021March 31, 2027ZAYTSEVA, YEKATERINAreporter.nih.gov
Regulation of CD8+T cells by Zbtb42NIHNational Cancer Institute2022 to 2025$1,705,648September 1, 2022August 31, 2027POOJARY, VENUPRASAD Kreporter.nih.gov
NR4A1 Antagonists Inhibit Colorectal Cancer Growth and Enhance Immune SurveillanceNIHNational Cancer Institute2023 to 2025$1,700,667January 1, 2023December 31, 2026SAFE, STEPHEN H.reporter.nih.gov
Development of an NTSR1-Targeted Radiotherapeutic for Colorectal CancerNIHNational Cancer Institute2021 to 2025$1,691,139April 1, 2021March 31, 2027GARRISON, JERED Creporter.nih.gov
I-SCREEN: Increasing Screening for Cancer using a Randomized Evaluation of EHR-based NudgesNIHNational Institute on Aging2022 to 2024$1,679,739August 15, 2020August 31, 2025NAVATHE, AMOL Sreporter.nih.gov
Oxidative pentose phosphate pathway regulates AMPK homeostasis by balancing opposing LKB1 and PP2ANIHNational Cancer Institute2021 to 2024$1,679,559April 15, 2014February 28, 2025CHEN, JINGreporter.nih.gov
Identifying the mechanism of anti-colorectal immunity induced by mucoinvasive colonic bacteriaNIHNational Cancer Institute2023 to 2025$1,677,626December 1, 2022November 30, 2027HAND, TIMOTHY WESLEYreporter.nih.gov
Molecular and Epigenetic Control of Wnt/b-catenin-mediated oncogenesis by KDM4BNIHNational Cancer Institute2021 to 2024$1,675,571February 1, 2020January 31, 2025WANG, CUN-YUreporter.nih.gov
Immune determinants modulating cancer development in Lynch SyndromeNIHNational Cancer Institute2024 to 2025$1,672,056June 15, 2024May 31, 2026BHARDWAJ, NINAreporter.nih.gov
IGFBP1 mediates a liver-bone-muscle axis in colorectal cancer cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,650,159September 1, 2022July 31, 2027BONETTO, ANDREAreporter.nih.gov
Novel synthetic lethality strategy for TP53 mutant colorectal cancerNIHNational Cancer Institute2023 to 2025$1,631,453August 10, 2023July 31, 2027FOUNTZILAS, CHRISTOSreporter.nih.gov
Interpretable deep learning models for translational medicine RenewalNIHNational Library of Medicine2021 to 2025$1,626,752April 1, 2015May 31, 2028LU, XINGHUAreporter.nih.gov
Regulation of DGAT - dependent lipogenesis in colonic epithelial growthNIHNational Cancer Institute2021 to 2025$1,619,709April 1, 2021June 30, 2026SAVKOVIC, SUZANA D.reporter.nih.gov
Role of Circadian Factors in Inflammation and Colorectal Adenoma RiskNIHNational Cancer Institute2021 to 2024$1,602,654September 11, 2019August 31, 2025BURCH, JAMESreporter.nih.gov
Novel TYRO3 inhibitors for treatment of cancerNIHNational Cancer Institute2021 to 2025$1,600,201April 1, 2021March 31, 2027WANG, XIAODONGreporter.nih.gov
Surgery triggered immune response and liver metastasesNIHNational Cancer Institute2022 to 2025$1,581,913January 1, 2018March 31, 2028TSUNG, ALLANreporter.nih.gov
Defining the Function of Age-Related Epimutation in Intestinal TumorigenesisNIHNational Cancer Institute2021 to 2025$1,579,721August 8, 2019July 31, 2030SHEN, LANLANreporter.nih.gov
Patient-Centered Reminders to Inform, Motivate, and Engage Colorectal Cancer Screening Adherence in Rural Communities: The PRIME-CRC TrialNIHNational Cancer Institute2021 to 2024$1,579,255June 1, 2020May 31, 2026ARNOLD, CONNIE L.reporter.nih.gov
Role of innate immunity and the microbiome in colitis-associated dysplasiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,577,776September 1, 2014April 30, 2027ABREU, MARIA TERESAreporter.nih.gov
Strategies for Optimizing a Mailed FIT Program in AppalachiaNIHNational Cancer Institute2023 to 2025$1,574,752August 28, 2023July 31, 2028REITER, PAUL Lreporter.nih.gov
Fatty acids and their receptors-mediated tumor metastasis and progressionNIHNational Cancer Institute2021 to 2024$1,574,167February 14, 2020January 31, 2026YU, HUA Ereporter.nih.gov
Multi-site Gastrointestinal Cancer Detection by Stool DNA MethylationNIHNational Cancer Institute2021 to 2024$1,573,848April 1, 2023March 31, 2025KISIEL, JOHNreporter.nih.gov
Znf740 in the regulation of CD8+T cell exhaustionNIHNational Cancer Institute2023 to 2025$1,563,506September 1, 2023August 31, 2028POOJARY, VENUPRASAD Kreporter.nih.gov
Geriatric assessment domains in relation to treatment outcomes among older adults with colorectal cancerNIHNational Institute on Aging2024 to 2025$1,562,259July 15, 2024March 31, 2029HARDIKAR, SHEETALreporter.nih.gov
ST8Sia6 expression on tumors inhibits the immune responseNIHNational Cancer Institute2021 to 2024$1,561,669December 1, 2019November 30, 2024SHAPIRO, VIRGINIA SMITHreporter.nih.gov
Role of the Epitranscriptome in CancerNIHNational Cancer Institute2024 to 2025$1,560,410August 1, 2019July 31, 2026GREGORY, RICHARD I.reporter.nih.gov
The Role of PHLPP in Colon CancerNIHNational Cancer Institute2021 to 2024$1,552,740April 1, 2009April 30, 2026GAO, TIANYANreporter.nih.gov
An ensemble deep learning model for tumor bud detection and risk stratification in colorectal carcinoma.NIHNational Cancer Institute2023 to 2025$1,550,974July 1, 2023June 30, 2028CHEN, WEIreporter.nih.gov
Cholesterol metabolism in mesenchymal colorectal cancerNIHNational Cancer Institute2023 to 2025$1,543,273December 9, 2022November 30, 2027MOSCAT, JORGEreporter.nih.gov
The Development of First-in-Class Inhibitors of Oncogenic CHD1L for the Treatment of Colorectal Cancer.NIHNational Cancer Institute2021 to 2024$1,530,498August 1, 2020April 30, 2026LABARBERA, DANIEL V.reporter.nih.gov
A novel, transferable sialylation-mediated mechanism of chemoradioresistance in GI cancerNIHNational Cancer Institute2022 to 2025$1,527,409February 1, 2022January 31, 2027HARDIMAN, KARIN MARIEreporter.nih.gov
MicroRNA control of tumor-promoting inflammation in colon cancerNIHNational Cancer Institute2022 to 2025$1,518,283February 8, 2022January 31, 2027GOPAL, MURUGAIYANreporter.nih.gov
Molecular Mechanisms of Fructose-induced Colorectal Cancer Cell SurvivalNIHNational Cancer Institute2022 to 2024$1,515,840January 10, 2022May 31, 2024GONCALVES, MARCUS DASILVAreporter.nih.gov
Impact of fasting on intestinal stem cells and cancerNIHNational Cancer Institute2021 to 2024$1,507,842September 1, 2020May 31, 2025YILMAZ, OMERreporter.nih.gov
Exploiting the distinct genomics and signaling of colorectal cancers to effectively target ERKNIHNational Cancer Institute2021 to 2024$1,502,540December 10, 2018November 30, 2024YAEGER, RONAreporter.nih.gov
Cancer in Your Community: Strategies to Reduce Cancer and Chronic Disease in the Arkansas DeltaNIHOffice of the Director, National Institutes of Health2023 to 2024$1,499,585September 21, 2023April 7, 2025MITCHELL, TRENAreporter.nih.gov
Colorectal Cancer Screening with Optical Coherence TomographyNIHNational Cancer Institute2024 to 2025$1,482,339August 1, 2024July 31, 2029TEARNEY, GUILLERMO Jreporter.nih.gov
Determining the structural- and functional-level effects of diet-specific interventions on the gut microbiota of a diverse sample of Southern United States adultsNIHNational Cancer Institute2021 to 2025$1,479,557June 1, 2021May 31, 2026CARSON, TIFFANY LASHAUNreporter.nih.gov
Characterization and targeting of rapid nucleotide exchange RAS mutationsNIHNational Cancer Institute2021 to 2024$1,473,768March 1, 2020February 28, 2025WESTOVER, KENNETHreporter.nih.gov
Targeting SUMO1 degradation for advanced colon cancer therapyNIHNational Cancer Institute2022 to 2025$1,470,853July 1, 2022June 30, 2027BELLAIL, ANITAreporter.nih.gov
Randomized controlled trial of the stool DNA test to improve colorectal cancer screening among Alaska Native peopleNIHNational Cancer Institute2021 to 2024$1,453,189April 1, 2020August 31, 2025REDWOOD, DIANAreporter.nih.gov
Reactivation of type I interferon pathway to increase the efficacy of chemotherapyNIHNational Cancer Institute2021 to 2024$1,453,040March 3, 2020February 28, 2025FUCHS, SERGE Yreporter.nih.gov
Couple Communication in Cancer: A Multi-Method Examination - Renewal - 1NIHNational Cancer Institute2024 to 2025$1,448,909September 20, 2016August 31, 2029LANGER, SHELBYreporter.nih.gov
Wnt signaling in obesity-associated colorectal cancerNIHNational Cancer Institute2022 to 2025$1,447,372May 23, 2022February 28, 2027ROPER, JATINreporter.nih.gov
The role of long noncoding RNA CRNDE in normal physiology and cancerNIHNational Cancer Institute2023 to 2025$1,444,226June 1, 2023May 31, 2028MENDELL, JOSHUA Treporter.nih.gov
Understanding how heme and iron are metabolized by anaerobic commensal bacteria and host-microbiome communitiesNIHNational Institute of General Medical Sciences2021 to 2025$1,426,148May 1, 2020February 28, 2026DUBOIS, JENNIFER Lreporter.nih.gov
Stimulating Lymphocyte Activation Combined with Inhibition of Immunosuppressive Signals in Colon Cancer MetastasesNIHNational Cancer Institute2022 to 2025$1,423,726January 22, 2020December 31, 2026MAKER, AJAY V.reporter.nih.gov
Targeting Translation Dependence in Colorectal Cancer ProgressionNIHNational Cancer Institute2021 to 2024$1,420,797April 1, 2013November 30, 2025SHE, QING-BAIreporter.nih.gov
Rational translation of gold nanoparticle mediated radiosensitization to the clinicNIHNational Cancer Institute2023 to 2025$1,412,352January 13, 2021December 31, 2026KRISHNAN, SUNILreporter.nih.gov
Refined Capture-Recapture Methods for Surveilling Cancer RecurrenceNIHNational Cancer Institute2022 to 2025$1,402,863September 20, 2022August 31, 2026LYLES, ROBERT Hreporter.nih.gov
p38gamma MAPK signaling promotes intestinal tumorigenesisNIHNational Cancer Institute2021 to 2025$1,395,284June 15, 2020May 31, 2026CHEN, GUANreporter.nih.gov
Body composition and adiposity-associated thromboinflammation in colorectal cancer prognosisNIHNational Cancer Institute2024 to 2025$1,388,285May 1, 2024April 30, 2028BYRD, DORATHA ARMENTHUSreporter.nih.gov
DNA Damage Repair by MUTYH and MUTYH Variants Associated with Colorectal CancerNIHNational Cancer Institute2021 to 2025$1,387,699July 15, 1995June 30, 2027DAVID, SHEILA SUEreporter.nih.gov
Addressing challenges in colorectal cancer risk predictionNIHNational Cancer Institute2024 to 2025$1,385,791June 7, 2024May 31, 2028NELSON, KERRIE Preporter.nih.gov
A microengineered colon cancer-chip designed to investigate tumor-stromal interactions driving cancer progressionNIHNational Cancer Institute2022 to 2025$1,384,529December 1, 2021November 30, 2026MUMENTHALER, SHANNON MICHELLEreporter.nih.gov
Elucidating the role of transcriptomics in driving ethnicity and ancestry-related disparities in colorectal cancerNIHNational Cancer Institute2024 to 2025$1,384,221April 1, 2024March 31, 2029FIGUEIREDO, JANE C.reporter.nih.gov
Tumor-Targeted Multimodality Nanoscale Coordination Polymers for Chemo-Immunotherapy of Metastatic Colorectal CancerNIHNational Cancer Institute2023 to 2025$1,377,117March 1, 2023February 29, 2028WEICHSELBAUM, RALPH Rreporter.nih.gov
Evaluating and Optimizing Novel nSMase2 Inhibitors in the Treatment of CancersNIHNational Cancer Institute2024 to 2025$1,375,950September 1, 2024August 31, 2029BLELLOCH, ROBERTreporter.nih.gov
Targeting ß-TrCP regulators to improve CRC response to chemotherapyNIHNational Cancer Institute2024 to 2025$1,375,343March 5, 2024February 28, 2029SPIEGELMAN, VLADIMIR S.reporter.nih.gov
Semi-supervised Approaches to Denoising Electronic Health Records Data for Risk PredictionNIHNational Library of Medicine2021 to 2024$1,374,026August 1, 2021April 30, 2026CAI, TIANXIreporter.nih.gov
Defining the mechanism of inositol 1,4,5-triphosphate receptor-mediated metastatic liver colonization in colorectal cancerNIHNational Cancer Institute2021 to 2025$1,373,770September 21, 2021August 31, 2026MOY, RYANreporter.nih.gov
mHealth Navigation using SMS Texting to Improve Colorectal Cancer Screening Among Homeless PersonsNIHNational Institute on Minority Health and Health Disparities2025$1,372,725September 19, 2025June 30, 2027ASGARY, RAMINreporter.nih.gov
FITting noninvasive testing into Lynch syndrome colorectal cancer surveillance: a multicenter, prospective trialNIHNational Cancer Institute2024 to 2025$1,371,823September 5, 2024August 31, 2029KUPFER, SONIAreporter.nih.gov
Nutrigenomics of Intestinal Vitamin D ActionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,369,028July 5, 2017March 31, 2028CHRISTAKOS, SYLVIA Sreporter.nih.gov
Interrogating the Role of Bacterial Methyl-modifying Enzymes in Pathoadaptation and Host Epigenetic Interference in CancerNIHNational Cancer Institute2024 to 2025$1,368,607August 5, 2024July 31, 2029JOHNSTON, CHRISTOPHER Dreporter.nih.gov
Cytokine-mediated regulation of immunity and microenvironment in colorectal cancer metastasisNIHNational Cancer Institute2024 to 2025$1,363,074January 9, 2024December 31, 2028GRIVENNIKOV, SERGEI Ireporter.nih.gov
Personalizing genetic test results management and outcomes after diagnosis of cancer: the Georgia-California SEER Genelink StudyNIHNational Cancer Institute2024 to 2025$1,362,587March 5, 2024February 28, 2029KURIAN, ALLISON W.reporter.nih.gov
Harnessing DNA methylation in peripheral blood for improved colorectal cancer preventionNIHNational Cancer Institute2024 to 2025$1,359,876August 1, 2024July 31, 2028SONG, MINGYANGreporter.nih.gov
Methodologic Innovations in Cancer EpidemiologyNIHNational Cancer Institute2023 to 2025$1,359,433March 1, 2023February 28, 2027ROSNER, BERNARD Areporter.nih.gov
Early detection of colorectal cancer in the traditional and serrated pathwaysNIHNational Cancer Institute2021 to 2024$1,349,852September 1, 2020August 31, 2025WANG, THOMAS Dreporter.nih.gov
Gain-of-function mutant p53 and metabolic reprogramming in colorectal cancerNIHNational Cancer Institute2023 to 2025$1,346,662April 1, 2021March 31, 2027HU, WENWEIreporter.nih.gov
Defining the role of seed and soil in peritoneal metastasis evolutionNIHNational Cancer Institute2024 to 2025$1,343,975May 1, 2024April 30, 2029NAXEROVA, KAMILAreporter.nih.gov
Implementing multilevel colon cancer screening interventions to reduce rural cancer disparitiesNIHNational Cancer Institute2021 to 2024$1,343,441July 15, 2019June 30, 2025JAMES, AIMEE Sreporter.nih.gov
Mechanisms of Serrated Colon Tumor SuppressionNIHNational Cancer Institute2023 to 2025$1,339,086June 8, 2023May 31, 2028VERZI, MICHAEL P.reporter.nih.gov
Assessment of hyperthermia-based multimodal approach for hepatic colorectal metastasesNIHNational Cancer Institute2023 to 2025$1,326,934September 19, 2023July 31, 2028LEE, YONG JUNreporter.nih.gov
Expanding access to colorectal cancer screening through community pharmacies: The PharmFIT studyNIHNational Cancer Institute2024 to 2025$1,316,228February 1, 2024January 31, 2029BRENNER, ALISON Treporter.nih.gov
Role for myeloid acid ceramidase in colon inflammation and cancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,315,037April 1, 2022March 31, 2027SNIDER, ASHLEY JONESreporter.nih.gov
Advanced Colonoscopy Training Developed Through Manikin Sensorization and Computational Optimization ModelingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,314,913July 1, 2023April 30, 2027MOORE, JASON ZACHARYreporter.nih.gov
Randomized Trial to Improve Care of Patients with Hereditary Cancer SyndromesNIHNational Cancer Institute2024 to 2025$1,314,067April 1, 2024March 31, 2029O'CONNOR, PATRICK Jreporter.nih.gov
Epithelial adherens junctions regulate colon cell behavior through RNAi and lncRNAsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,314,045March 26, 2021February 28, 2026KOURTIDIS, ANTONISreporter.nih.gov
Nanoscale Coordination Polymers of Cyclic-di-nucleotides and Peptide Antigens for Effective Therapy of Metastatic Colorectal CancerNIHNational Cancer Institute2023 to 2025$1,313,375June 1, 2023May 31, 2028WEICHSELBAUM, RALPH Rreporter.nih.gov
Immunomodulatory Effects of Targeting DNA Repair with Novel Temozolomide Combinations in Colorectal CancerNIHNational Cancer Institute2021 to 2025$1,304,790August 5, 2021September 30, 2026CECCHINI, MICHAELreporter.nih.gov
Development of blood-based methylation biomarkers for CRC risk predictionNIHNational Cancer Institute2023 to 2025$1,300,887September 20, 2023August 31, 2028GHOSH, JAYASHRIreporter.nih.gov
Predicting neoadjuvant treatment response of locally advanced rectal cancer using co-registered endo-rectal photoacoustic and ultrasound imagingNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,298,022May 1, 2023April 30, 2027ZHU, QUINGreporter.nih.gov
Translational Science of Gastrointestinal Cancer Initiation and ProgressionNIHNational Cancer Institute2021 to 2025$1,289,608September 19, 2018August 31, 2028YU, MINGreporter.nih.gov
Roles for Intracellular pH Dynamics in CancerNIHNational Cancer Institute2021 to 2025$1,284,345June 1, 2016March 31, 2028BARBER, DIANE Lreporter.nih.gov
Biology of R-Spondin-Induced Sensitization to Asparaginase in Colorectal CancerNIHNational Cancer Institute2024 to 2025$1,282,528August 1, 2021July 31, 2027GUTIERREZ, ALEJANDROreporter.nih.gov
MS4A7 in tumor resistance to immunotherapyNIHNational Cancer Institute2024 to 2025$1,281,774March 5, 2024February 28, 2029ZOU, WEIPINGreporter.nih.gov
Single-molecule nanopore-based identification of methylome signatures in cfDNA for early colorectal cancer detectionNIHNational Cancer Institute2024 to 2025$1,280,475September 1, 2024August 31, 2029JI, HANLEE Preporter.nih.gov
BET degraders for improving colorectal cancer therapyNIHNational Cancer Institute2023 to 2025$1,279,978October 9, 2023March 31, 2027ZHANG, LINreporter.nih.gov
Targeting GARP-TGFbeta for Immunotherapy of Non-Small Cell Lung CancerNIHNational Cancer Institute2024 to 2025$1,273,521September 1, 2024August 31, 2029LI, ZIHAIreporter.nih.gov
Mechanisms of DNA methylation signaling and dysregulation in colon cancerNIHNational Cancer Institute2024 to 2025$1,264,638July 2, 2024June 30, 2029ROTHBART, SCOTTreporter.nih.gov
A magnetic capsule endoscope for colonoscopy in patients with inflammatory bowel diseaseNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,258,230September 18, 2014December 31, 2025OBSTEIN, KEITH Lreporter.nih.gov
MGH- PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal TumorsNIHNational Cancer Institute2024 to 2025$1,257,849May 1, 2024April 30, 2026CHAN, ANDREW Treporter.nih.gov
Defining the landscape of bacterial-colonized microniches in tumors and their role in intratumoral heterogeneity.NIHNational Cancer Institute2024 to 2025$1,247,680September 1, 2024August 31, 2029BULLMAN, SUSANreporter.nih.gov
Bacteria-derived xenobiotics in colon cancer prevention: Link to GPR109A and colonic ketogenesisNIHNational Cancer Institute2023 to 2025$1,247,181July 7, 2023June 30, 2028THANGARAJU, MUTHUSAMYreporter.nih.gov
Project Title: Low-dose erlotinib and mesalamine for prevention of colitis-associated colorectal cancer (CAC)NIHNational Cancer Institute2024 to 2025$1,246,808September 25, 2025March 24, 2027VILAR SANCHEZ, EDUARDOreporter.nih.gov
Interrogating the role of arachidonic acid metabolism in modulating the tumor immune microenvironment as a novel path to therapeutic interventionNIHNational Cancer Institute2024 to 2025$1,246,745September 6, 2024August 31, 2029YEATMAN, TIMOTHY Jreporter.nih.gov
Aspirins legacy on cancer and overall benefit: risk balance over a 15-year horizonNIHNational Cancer Institute2024 to 2025$1,238,913September 26, 2024August 31, 2029WARNER, ERICA Treporter.nih.gov
Investigating the contribution of cellular senescence to the efficacy of radiation therapy.NIHNational Cancer Institute2021 to 2025$1,237,994September 1, 2021August 31, 2026ROMESSER, PAUL BERNARDreporter.nih.gov
Evaluating a Multilevel Intervention to Increase Colonoscopic Follow-up after Abnormal Stool-based Colorectal Cancer Screening in a Community Safety-Net SettingNIHNational Cancer Institute2024 to 2025$1,230,397September 5, 2024August 31, 2029MAY, FOLASADE POPOOLAreporter.nih.gov
PB-iCRC: Multi-site Practice-Based Implementation of a ColoRectal Cancer screening interventionNIHNational Cancer Institute2024 to 2025$1,229,626May 10, 2024April 30, 2029LEMASTER, JOSEPH Wreporter.nih.gov
The regulation of mutant p53 protein accumulation in cancer: molecular basis and therapeutic potentialNIHNational Cancer Institute2023 to 2025$1,225,741July 1, 2021June 30, 2027FENG, ZHAOHUIreporter.nih.gov
MTGs in Intestinal Biology and Injury ResponsesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,223,368July 1, 2024May 31, 2028WILLIAMS, CHRISTOPHER S.reporter.nih.gov
Elucidating the role and mechanisms by which collagenase producing intestinal bacteria promote colorectal cancer recurrence and metastasis following surgery.NIHNational Cancer Institute2021 to 2025$1,208,495January 1, 2021December 31, 2025SHOGAN, BENJAMINreporter.nih.gov
LIN28B promotes colorectal cancer differentiation and metastasisNIHNational Cancer Institute2023 to 2025$1,202,020March 1, 2000March 31, 2028RUSTGI, ANIL Kreporter.nih.gov
Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal CancerNIHNational Cancer Institute2024 to 2025$1,199,980May 1, 2024April 30, 2029MOSHER, CATHERINE Ereporter.nih.gov
The lysosomal fasting response in intestinal stem cells and cancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,198,646August 15, 2024June 30, 2028YILMAZ, OMERreporter.nih.gov
Safety and Efficacy Trial of the ColoSeal ICD System for the Treatment of Diverticular Disease PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$1,192,362September 19, 2025August 31, 2027FONG, KENTON DODYANreporter.nih.gov
Targeting the Sam68-stimulated PARP1 activation for cancer treatmentNIHNational Cancer Institute2021 to 2025$1,190,833June 1, 2020October 1, 2025WAN, FENGYIreporter.nih.gov
Transfer RNA sequencing and application to cancer research and clinicsNIHNational Cancer Institute2022 to 2024$1,187,465September 15, 2022August 31, 2025PAN, TAOreporter.nih.gov
A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer researchNIHNational Cancer Institute2022 to 2024$1,181,771June 8, 2022May 31, 2026CHIU, BRIAN C-Hreporter.nih.gov
Targeting the Immunosuppressive Tumor Microenvironment for Colorectal Cancer TreatmentNIHNational Cancer Institute2023 to 2025$1,180,814September 1, 2023August 31, 2028WANG, QINGDINGreporter.nih.gov
Using Natural Language Processing and Crowdsourcing to Monitor and Evaluate Public Information and Communication Disparities about Colon Cancer ScreeningNIHNational Cancer Institute2023 to 2025$1,174,537April 15, 2021February 28, 2027KING, ANDY Jreporter.nih.gov
Assessing the long-term impacts of the COVID-19 pandemic on disparities in cancer screening and follow-up (RESTORE)NIHNational Cancer Institute2024 to 2025$1,174,468July 15, 2021June 30, 2027CORONADO, GLORIA D.reporter.nih.gov
The oral-gut axis in colorectal cancerNIHNational Cancer Institute2024 to 2025$1,161,644March 1, 2024February 28, 2029KAMADA, NOBUHIKOreporter.nih.gov
Expanding cancer research capacity in Nigeria with team scienceNIHNational Cancer Institute2022 to 2025$1,160,841March 8, 2022February 28, 2027KINGHAM, T PETERreporter.nih.gov
muMS2: an open source R package for analyzing and integrating multi-omics datasets to improve early detection and understanding of colorectal cancerNIHNational Cancer Institute2022 to 2024$1,150,435June 1, 2022May 31, 2025SCHLOSS, PATRICK DAVIDreporter.nih.gov
Three-Dimensional Multi-Parametric Ultrasound for Monitoring Therapy of Liver MetastasisNIHNational Cancer Institute2023 to 2025$1,150,411April 1, 2016February 28, 2027EL KAFFAS, AHMEDreporter.nih.gov
Study of PTPRF-Mediated Regulation of Wnt SignalingNIHNational Institute of General Medical Sciences2023 to 2025$1,133,508June 1, 2023March 31, 2027GAO, TIANYANreporter.nih.gov
International Study of Subsequent Colorectal Cancer Among Survivors of Childhood, Adolescent, and Young Adult Cancers (I-SCRY)NIHNational Cancer Institute2022 to 2024$1,132,151February 8, 2022January 31, 2026MOSKOWITZ, CHAYAreporter.nih.gov
A Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of an Intervention to Promote Guideline-Concordant Colorectal Cancer SurveillanceNIHNational Cancer Institute2024 to 2025$1,122,732August 1, 2024July 31, 2029VEENSTRA, CHRISTINEreporter.nih.gov
Functional and molecular characterization of Oncofetal Stem Cells in CRCNIHNational Cancer Institute2024 to 2025$1,120,594September 1, 2024August 31, 2029MZOUGHI, SLIMreporter.nih.gov
Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III StudyNIHNational Cancer Institute2021 to 2024$1,106,695January 10, 2019December 31, 2025SMITH, ELLEN MARY LAVOIEreporter.nih.gov
A20 and Tumor Immune ResponsesNIHNational Cancer Institute2024 to 2025$1,105,779August 1, 2024July 31, 2026MA, AVERIL Ireporter.nih.gov
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancerNIHNational Cancer Institute2021 to 2024$1,104,519July 1, 2019December 31, 2024BAYLIN, STEPHEN B.reporter.nih.gov
Molecular mechanisms of developmental reprogramming in colorectal cancerNIHNational Cancer Institute2024 to 2025$1,103,696September 1, 2024August 31, 2029SETHI, NILAYreporter.nih.gov
MRI and blood biomarkers of neoadjuvant therapy response and outcomes in rectal cancerNIHNational Cancer Institute2024 to 2025$1,098,438February 1, 2024January 31, 2029LI, RUIJIANGreporter.nih.gov
Sulindac sensitizes colorectal cancer to anti-PD-L1 therapyNIHNational Cancer Institute2023 to 2024$1,096,423August 1, 2023July 31, 2027XI, YAGUANGreporter.nih.gov
ROLE OF SORD IN SUGAR-MEDIATED CANCER METASTASISNIHNational Cancer Institute2022 to 2025$1,087,515March 8, 2022February 28, 2028YUN, JIHYEreporter.nih.gov
Armed nanobodies as anti-infectives and anti-tumor agentsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,085,800July 19, 2024May 31, 2029WU, HAOreporter.nih.gov
Hereditary Cancer Variants of Uncertain Significance in Stem CellsNIHNational Cancer Institute2021 to 2024$1,085,466April 4, 2019March 31, 2026HEINEN, CHRISTOPHER D.reporter.nih.gov
Systematic liquid biopsy to monitor residual disease and treatment efficacy in gastrointestinal cancer patientsNIHNational Cancer Institute2022 to 2025$1,079,955September 5, 2022June 30, 2027PARIKH, APARNA RAJreporter.nih.gov
Engineering S. typhimurium for metastatic colorectal cancerNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$1,060,835June 15, 2020November 30, 2025DANINO, TALreporter.nih.gov
A 4D-tunable hydrogel for the study of the impact of the tumor microenvironment on the development of colorectal cancerNIHNational Cancer Institute2024 to 2025$1,050,192July 1, 2024June 30, 2029ALLBRITTON, NANCY L.reporter.nih.gov
Towards a complete characterization of the metastasis founder clones in colorectal cancerNIHNational Cancer Institute2023 to 2025$1,046,031July 1, 2023December 31, 2028NAXEROVA, KAMILAreporter.nih.gov
Automated Colorectal Cancer Educational Support System (ACCESS): Development and Validation of a Novel Online Decision Aid for Improving Colorectal Cancer Screening UptakeNIHNational Cancer Institute2021 to 2024$1,043,808July 1, 2020June 30, 2026ALMARIO, CHRISTOPHER Vreporter.nih.gov
Assessing residential neighborhood exposome exposures and the associations with cancer incidenceNIHNational Cancer Institute2023 to 2025$1,035,844July 8, 2023June 30, 2028PERERA, ROBERT ANTHONYreporter.nih.gov
A vascularized microphysiological system (MPS) platform for modeling peritoneal carcinomatosisNIHNational Cancer Institute2024 to 2025$1,022,846June 1, 2024May 31, 2026HUGHES, CHRISTOPHER C. W.reporter.nih.gov
PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal TumorsNIHNational Cancer Institute2024 to 2025$1,020,731May 1, 2024April 30, 2026BALSKUS, EMILY PATRICIAreporter.nih.gov
The role of leukemia inhibitory factor in colorectal cancerNIHNational Cancer Institute2023 to 2025$1,018,588February 1, 2022January 31, 2027HU, WENWEIreporter.nih.gov
Mitochondrial bioenergetics and colorectal cancerNIHNational Cancer Institute2024 to 2025$1,018,451February 19, 2024May 31, 2029FISHER-WELLMAN, KELSEY Hreporter.nih.gov
The role of the mycobiome in cancerNIHNational Cancer Institute2024 to 2025$1,017,386February 1, 2024January 31, 2029ILIEV, ILIYAN DIMITROVreporter.nih.gov
A Phospholipid-Derived Nanotherapeutic Platform for Improved Colorectal Cancer ImmunochemotherapyNIHNational Cancer Institute2023 to 2025$1,016,541April 1, 2023March 31, 2028LU, JIANQINreporter.nih.gov
Enteric Glia is New Biological Target to Block Drug Resistance in Colon CancerNIHNational Cancer Institute2023 to 2025$993,191April 1, 2023March 31, 2028VAN LANDEGHEM, LAURIANNE CHANTALreporter.nih.gov
Assembly and function of outer membrane tubules in Fusobacterium nucleatumNIHNational Institute of Dental & Craniofacial Research2024 to 2025$988,946May 1, 2024April 30, 2029TON-THAT, HUNGreporter.nih.gov
Advancing top-down proteomics with capillary electrophoresis-mass spectrometryNIHNational Institute of General Medical Sciences2024 to 2025$983,629May 1, 2024April 30, 2029SUN, LIANGLIANGreporter.nih.gov
Development of SUV39H1-selective inhibitor for human colon cancer therapyNIHNational Cancer Institute2024 to 2025$982,509February 1, 2024January 31, 2029LIU, KEBINreporter.nih.gov
Mechanism and approach to inactivate mutant KRAS of lung metastatic colon cancer by RNA-ligand-displaying exosome to co-deliver dCas9--gRNA ribonucleoprotein complex and KRAS siRNANIHNational Cancer Institute2024 to 2025$972,447July 2, 2024June 30, 2026GUO, PEIXUANreporter.nih.gov
Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platformNIHNational Cancer Institute2022 to 2025$962,266September 13, 2022August 31, 2027EYLER, CHRISTINE ELISSAreporter.nih.gov
TLR Agonist Nano-Immune Therapy for Peritoneal MetastasesNIHNational Cancer Institute2024 to 2025$948,125September 9, 2024August 31, 2029SERDA, RITA ELENAreporter.nih.gov
Research and mentoring program in shared decision making in the care of older adultsNIHNational Institute on Aging2021 to 2025$946,256April 1, 2021March 31, 2027SCHONBERG, MARA Areporter.nih.gov
Targeting defective necroptosis in colorectal cancerNIHNational Cancer Institute2023 to 2024$926,503December 1, 2019March 31, 2026ZHANG, LINreporter.nih.gov
Colon cell mechanoregulation through an E-cadherin - associated RNAi machineryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$926,351April 1, 2024March 31, 2028KOURTIDIS, ANTONISreporter.nih.gov
Mechanisms for environmental microplastics-enhanced colorectal tumor progressionNIHNational Institute of Environmental Health Sciences2024 to 2025$909,141August 16, 2024July 31, 2029XUE, XIANGreporter.nih.gov
Building a Cancer Epidemiology Cohort to Investigate Factors Associated with Higher Risk of Colorectal Cancer among Alaska Native PeopleNIHNational Cancer Institute2024 to 2025$893,216August 1, 2024July 31, 2029REDWOOD, DIANAreporter.nih.gov
Elucidating the impact of DNA hypomethylation on genome organization and anti-tumor transcriptional programsNIHNational Cancer Institute2021 to 2025$888,619April 1, 2021March 31, 2027JOHNSTONE, SARAH Ereporter.nih.gov
Assessment of strategies for targeting transcriptional co-activators in colorectal cancerNIHNational Cancer Institute2024 to 2025$885,766August 15, 2024July 31, 2029FISHER, KURTreporter.nih.gov
Biomarker discovery in colon cancer through next-generation metabolomicsNIHNational Cancer Institute2025$881,647September 2, 2025August 31, 2027STANCLIFFE, ETHANreporter.nih.gov
Validation of blood-based predictive biomarkers of therapeutic response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancerNIHNational Cancer Institute2024 to 2025$870,915May 1, 2022April 30, 2027ARORA, SANJEEVANIreporter.nih.gov
Targeting LSD1 to prevent therapy-induced transdifferentiation in BRAF mutant colorectal cancerNIHNational Cancer Institute2024 to 2025$866,472April 1, 2024March 31, 2029O'HAGAN, HEATHER Mreporter.nih.gov
Regulation of RBP Function during EMTNIHNational Cancer Institute2024 to 2025$853,791May 1, 2024April 30, 2029LEWIS, ROBERT E.reporter.nih.gov
Molecular Mechanisms of Fructose-induced Colorectal Cancer Cell SurvivalNIHNational Cancer Institute2024 to 2025$845,322January 10, 2022December 31, 2026GONCALVES, MARCUS DASILVAreporter.nih.gov
Type VII secretion in Streptococcus gallolyticus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$842,340December 1, 2023October 31, 2028XU, YIreporter.nih.gov
Improving Diagnosis in Gastrointestinal Cancer: Integrating Prediction Models into Routine Clinical CareNIHNational Cancer Institute2023 to 2025$829,581July 1, 2023June 30, 2027READ, ANDREW Jreporter.nih.gov
Mutant p53 gain-of-function as an actionable target in cancer therapyNIHNational Cancer Institute2021 to 2024$828,596September 11, 2020August 31, 2025NEMAJEROVA, ALICEreporter.nih.gov
PROSPECT - Stem cell modelsNIHNational Cancer Institute2024 to 2025$811,617May 1, 2024April 30, 2026YILMAZ, OMERreporter.nih.gov
Fatty Acid Synthase as a Novel Molecular Target for Colon Cancer TreatmentNIHNational Cancer Institute2024 to 2025$805,936March 1, 2024February 28, 2029GAO, TIANYANreporter.nih.gov
Neoadjuvant Tucatinib plus Trastuzumab in HER2-amplified Locally Advanced Rectal CancerNIHNational Cancer Institute2024 to 2025$805,200March 1, 2024February 28, 2029CERCEK, ANDREAreporter.nih.gov
Mechanisms of metabolic reprogramming by PIK3CA oncogenic mutationsNIHNational Cancer Institute2024 to 2025$805,000January 17, 2024December 31, 2028WANG, ZHENGHEreporter.nih.gov
Physical activity intervention co-created and pilot tested with African American Colorectal Cancer SurvivorsNIHNational Institute on Minority Health and Health Disparities2021 to 2025$795,103May 3, 2021January 31, 2026HIRSCHEY, RACHELreporter.nih.gov
Regulation and Localization of Mismatch Repair ProteinsNIHNational Institute of General Medical Sciences2022 to 2025$794,650August 1, 2022May 31, 2027HAYE, JOANNA Ereporter.nih.gov
The Impact of HIV on the Tumor Microenviornment and Survival in Colorectal Cancer Patients in South AfricaNIHNational Cancer Institute2024 to 2025$779,156April 1, 2024March 31, 2029HERSHMAN, DAWNreporter.nih.gov
Imaging nanoscale chromatin folding in early carcinogenesisNIHNational Cancer Institute2023 to 2025$777,902August 1, 2020May 31, 2026LIU, YANGreporter.nih.gov
A Targeted Approach to Treat Immunotherapy-Induced Myocarditis with CXCR3 BlockadeNIHNational Heart, Lung, and Blood Institute2025$773,843September 19, 2025May 31, 2029ZHU, HANreporter.nih.gov
Mechanistic and Pharmacokinetic Studies of Classical Chinese Formula Xiao Chai Hu Tang Against Irinotecan-Induced Gut ToxicitiesNIHNational Cancer Institute2021 to 2024$769,859September 11, 2020June 30, 2025HU, MINGreporter.nih.gov
Exploiting Carbon Monoxide Biofoams to Radio-Sensitize Rectal Cancer Cells While Protecting Normal BowelNIHNational Cancer Institute2023 to 2025$756,848June 9, 2023May 31, 2028BYRNE, JAMES DONALDreporter.nih.gov
Discovery of host genetic elements affecting response to immune checkpoint inhibitorsNIHNational Cancer Institute2025$754,511December 13, 2024November 30, 2029LIU, EDISON TAK-BUNreporter.nih.gov
Leveraging artificial intelligence/machine learning-based technology to overcome specialized training and technology barriers for the diagnosis and prognostication of colorectal cancer in AfricaNIHNational Cancer Institute2023 to 2025$749,998September 15, 2023August 31, 2026SALEH, MANSOOR Nreporter.nih.gov
Novel radiomic signatures for treatment response to neoadjuvant therapy in rectal cancersNIHNational Cancer Institute2024 to 2025$749,106May 15, 2024September 15, 2025VISWANATH, SATISH EASWARreporter.nih.gov
Genetics of Tumor Suppression by p53NIHNational Cancer Institute2022 to 2024$747,000March 4, 2020November 30, 2024BARNOUD, THIBAUTreporter.nih.gov
Understanding methionine metabolism and its therapeutic potential in cancerNIHNational Cancer Institute2022 to 2024$747,000April 1, 2022September 30, 2025GAO, XIAreporter.nih.gov
Elucidating the Role of SMAD4 in Colorectal CancerNIHNational Cancer Institute2022 to 2024$747,000July 1, 2022June 30, 2026TONG, KEVINreporter.nih.gov
Targeting the IL-33/ST2 Pathway in Colorectal Cancer ImmunotherapyNIHNational Cancer Institute2023 to 2025$747,000February 1, 2023January 31, 2026VAN DER JEUGHT, KEVINreporter.nih.gov
Functional characterization of novel oncogenic loci driving progression and immune response in gastrointestinal cancerNIHNational Cancer Institute2023 to 2025$747,000September 1, 2021August 31, 2026LO, YUAN-HUNGreporter.nih.gov
Developing multiplexed microenvironmental sensors for precision diagnostics of cancer metastasisNIHNational Cancer Institute2023 to 2025$747,000January 1, 2020February 28, 2026HAO, LIANGLIANGreporter.nih.gov
InSiGHT-ClinGen Polyposis/Colon Cancer Variant Curation Expert PanelNIHNational Cancer Institute2021 to 2024$745,538June 10, 2021May 31, 2026GREENBLATT, MARC Sreporter.nih.gov
Characterization of polyamine biosynthetic enzymes from human gut microbes associated with colon and pancreatic cancerNIHNational Institute of General Medical Sciences2022 to 2025$744,530July 15, 2022June 30, 2027MCFARLANE, JEFFREY Sreporter.nih.gov
Exploring the impact of HSP90 inhibition on antigen presentation and anti-tumor immune responsesNIHNational Cancer Institute2022 to 2024$742,016March 2, 2020February 28, 2025JAEGER, ALEXreporter.nih.gov
Role of lncRNA UCA1 in anoikis resistantce and colorectal cancer metastasisNIHNational Institute of General Medical Sciences2022 to 2025$740,000September 1, 2022July 31, 2027TRIPATHI, MANISH Kreporter.nih.gov
Role of LRG1 in colorectal cancer tumorigenesisNIHNational Cancer Institute2024 to 2025$736,576February 1, 2024January 31, 2029WANG, RUIreporter.nih.gov
Polyunsaturated fatty acids and colorectal tumor risk: a molecular and genetic epidemiology studyNIHNational Cancer Institute2021 to 2024$736,512February 1, 2021July 31, 2025KHANKARI, NIKHIL KISHORreporter.nih.gov
Illuminating the evolutionary history of colorectal cancer metastasis: basic principles and clinical applicationsNIHNational Cancer Institute2023 to 2024$735,681September 1, 2023May 14, 2025NAXEROVA, KAMILAreporter.nih.gov
Leveraging Radiation-Induced Senescence and PTPN2 Inhibition to Enhance Immune-Mediated Tumor Control in Rectal CancerNIHNational Cancer Institute2025$730,398September 1, 2025August 31, 2030ROMESSER, PAUL BERNARDreporter.nih.gov
Engineered probiotic bacteria for colorectal cancer immunoprevention and interceptionNIHNational Cancer Institute2025$727,904August 11, 2025May 31, 2027ARPAIA, NICHOLASreporter.nih.gov
Persistent Poverty and Colorectal Cancer Risk: Elucidating biological, behavioral, and place-based pathwaysNIHNational Cancer Institute2025$724,840August 21, 2025July 31, 2030CHENG, IONA Creporter.nih.gov
Increasing CRC Screening in Community Health Centers through Mobile Messaging OptimizationNIHNational Cancer Institute2025$724,556August 1, 2025July 31, 2030KRUSE, GINA RAEreporter.nih.gov
Dissecting roles of microbiome-host interactions in colorectal neoplasia etiology using multi-omics dataNIHNational Cancer Institute2023 to 2025$723,990January 5, 2021March 31, 2027YANG, YAOHUAreporter.nih.gov
Chemical synthesis to access rare heterocycles and tool compounds to probe bacterial polysaccharide metabolismNIHNational Institute of General Medical Sciences2024 to 2025$721,207September 1, 2024June 30, 2029WHITEHEAD, DANIEL CHARLESreporter.nih.gov
Automated Multi-Timepoint CT Analysis for Enhanced Metastatic Disease Evaluation in Colorectal Cancer: An Anatomy-Aware Vision-Language AI ApproachNIHNational Institute of Biomedical Imaging and Bioengineering2025$718,456July 1, 2025May 31, 2029WANG, KANGreporter.nih.gov
The Meharry Cancer Summer Research Program (SuRP)NIHNational Cancer Institute2023 to 2025$717,582September 1, 2023August 31, 2028STEWART, LAMONICA VANETTEreporter.nih.gov
Addressing cancer disparities in Nigeria through Immuno-oncology Research – The NOLA ProgramNIHNational Cancer Institute2024 to 2025$716,532September 16, 2024August 31, 2026KINGHAM, T PETERreporter.nih.gov
T helper cells and stem cells in colon homeostasis and tumor initiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$715,501March 15, 2025January 31, 2030HAN, ARNOLDreporter.nih.gov
Redefining indications of EGFR inhibitors in cancers that harbor mutant RASNIHNational Cancer Institute2024 to 2025$713,700September 1, 2024August 31, 2029MCFALL, THOMAS BRADLEYreporter.nih.gov
The regulation of gut macrophage’s function by the bile acid receptor FXRNIHNational Cancer Institute2024 to 2025$711,412May 1, 2024April 30, 2029FU, TINGreporter.nih.gov
A spatial profiling-based immune hub perturbation platform to improve immunotherapy in colon cancerNIHNational Cancer Institute2025$710,361August 1, 2025May 31, 2030PELKA, KARINreporter.nih.gov
Prebiotic effect of eicosapentaenoic acid treatment for colorectal cancer livermetastasisNIHNational Cancer Institute2024$710,138July 1, 2024May 19, 2025GARRETT, WENDY S.reporter.nih.gov
Dissecting the in vivo stromal metabolic and inflammatory crosstalk in colorectal cancerNIHNational Cancer Institute2022 to 2025$701,144August 16, 2022July 31, 2027DURAN MOLINA, MARIA ANGELESreporter.nih.gov
Deciphering the Critical Determinants of Enteric and Tumor Niche Colonization by Microbes in Colorectal CancerNIHNational Cancer Institute2025$697,763February 1, 2025January 31, 2030JOHNSTON, CHRISTOPHER Dreporter.nih.gov
Exercise as Interception Therapy in Primary High Risk CancerNIHNational Cancer Institute2025$693,662September 3, 2020June 30, 2027JONES, LEE Wreporter.nih.gov
A non-invasive blood test for multi-cancer detection and determination of tissue of origin preceding overt cancer diagnosisNIHNational Cancer Institute2025$692,491May 1, 2025April 30, 2030BISSONNETTE, BRUCE MARCreporter.nih.gov
Role and Regulation of Asparagine in Colorectal CancerNIHNational Cancer Institute2025$688,092January 1, 2025December 31, 2029JOHNSON, CAROLINE HELENreporter.nih.gov
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon CancerNIHNational Cancer Institute2024 to 2025$675,764June 3, 2022May 31, 2028BROWN, JUSTIN Creporter.nih.gov
Addressing Colorectal Cancer-Related Distress: Developing and Evaluating a Couple-Based Mindfulness InterventionNIHNational Cancer Institute2022 to 2025$672,640August 12, 2022August 31, 2027ZIMMARO, LAUREN A.reporter.nih.gov
Optical hyperspectral nanoscale chromatin analysis for colon cancer risk-stratificationNIHNational Cancer Institute2025$670,534May 1, 2025April 30, 2030BACKMAN, VADIMreporter.nih.gov
A Systems Theory Approach to the Study of Colon and Lung Cancer Survivorship Using Novel Data LinkagesNIHNational Cancer Institute2024 to 2025$669,183September 16, 2024August 31, 2029ADAMS, SWANN ARPreporter.nih.gov
Regulatory role for an epithelial repair protein, LINGO2, in colitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$667,440July 1, 2020March 31, 2025BELLE, NICOLE MALONEYreporter.nih.gov
Discovery and verification of methylated circulating tumor DNA markers for the detection of colorectal cancer in subjects under 50 years of ageNIHNational Cancer Institute2025$663,923July 1, 2021June 30, 2027HITCHINS, MEGAN Preporter.nih.gov
Tumor-Selective Radiosensitization by Targeting Hypoxia in Rectal CancerNIHNational Cancer Institute2025$662,096February 1, 2025January 31, 2030WILLIAMS, TERENCE MARQUESreporter.nih.gov
Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosisNIHNational Cancer Institute2025$658,336June 1, 2025May 31, 2028GEORGE, TADreporter.nih.gov
Metabolic reprogramming to boost the fitness of anti-tumor immunity against metastatic colon cancerNIHNational Cancer Institute2025$640,583April 1, 2025March 31, 2030BEYAZ, SEMIRreporter.nih.gov
Interventions to Decrease Cancer Information AvoidanceNIHNational Cancer Institute2025$637,596April 4, 2025March 31, 2030OROM, HEATHERreporter.nih.gov
A community-engaged intervention to increase colorectal cancer screening in communities with suboptimal screeningNIHNational Cancer Institute2022 to 2025$635,025September 14, 2022August 31, 2027VANG, SUZANNE SHARRYreporter.nih.gov
Impact of Aspirin on the Gut Microbiome and Mucosal MicroenvironmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$632,880February 6, 2020February 28, 2025DREW, DAVID Areporter.nih.gov
Targeting a human gut bacterial genotoxin via engineered commensal bacteriaNIHNational Cancer Institute2025$627,422May 1, 2025April 30, 2030LI, JIAHEreporter.nih.gov
Improving colorectal cancer screening decisions through consideration of life expectancyNIHNational Institute on Aging2025$625,452January 1, 2025December 31, 2029MARTINEZ, KATHRYN ANNEreporter.nih.gov
Influence of developmental programming in adult stem cells and cancerNIHNational Cancer Institute2025$621,570August 8, 2025July 31, 2030MANA, MIYEKOreporter.nih.gov
PROACT: Promoting Follow-up of Abnormal Colorectal Cancer Screening Tests through Multilevel InterventionsNIHNational Cancer Institute2025$621,406August 1, 2025July 31, 2030ISSAKA, RACHEL B.reporter.nih.gov
3D Engineered Model of Microscopic Colorectal Cancer Liver Metastasis for Adjuvant Chemotherapy ScreensNIHNational Cancer Institute2023 to 2025$620,295January 1, 2023December 31, 2028RAGHAVAN, SHREYA A.reporter.nih.gov
The Role of Prohibitin 1 in Ethanol's Sensitizing Effect on Colorectal Liver MetastasisNIHNational Institute on Alcohol Abuse and Alcoholism2025$617,748September 10, 2025June 30, 2030LU, SHELLY CHI-LOOreporter.nih.gov
Discovery and Development of Natural Products for Interception of CRCNIHNational Cancer Institute2024 to 2025$607,750May 14, 2024April 30, 2027RAO, CHINTHALAPALLY V.reporter.nih.gov
Metabolic modulation of Fusobacterium nucleatum virulenceNIHNational Institute of Dental & Craniofacial Research2023 to 2024$604,857March 1, 2023February 28, 2026TON-THAT, HUNGreporter.nih.gov
Mechanisms and strategies to rescue suboptimal T cell priming in colon cancerNIHNational Cancer Institute2023 to 2025$603,126September 1, 2023August 31, 2026WESTCOTT, PETER MAXWELL KIENITZreporter.nih.gov
Decoding the functional pleiotropy of IL-20Rβ ligands in inflammation and tumorigenesisNIHNational Cancer Institute2023 to 2025$600,696February 20, 2023January 31, 2026SAXTON, ROBERT ANDREWreporter.nih.gov
Microbial and host biomarkers in colorectal cancer oncogenesisNIHNational Cancer Institute2025$600,499April 1, 2025March 31, 2030HAN, YIPINGreporter.nih.gov
Chimeric RNA driven neopeptide vaccine for prevention of breast cancer in germline BRCA1/2 carriersNIHNational Cancer Institute2025$597,289July 9, 2025June 30, 2027BEDROSIAN, ISABELLEreporter.nih.gov
Computational approaches to the mechanistic elucidation of the serrated pathway of human colon carcinogenesisNIHNational Cancer Institute2023 to 2025$596,163August 1, 2023July 31, 2028MOUSSA, MARMARreporter.nih.gov
A Novel Nanodrug for Metabolic Disease TreatmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$594,547September 2, 2024August 31, 2025WAN, YU-JUI YVONNEreporter.nih.gov
Engineering ingestible nanosensors for breath-based detection of colorectal cancerNIHNational Cancer Institute2025$592,866March 15, 2025February 28, 2030CHAN, LESLIEreporter.nih.gov
Optimization of an active mutant KRAS peptide vaccine in colorectal cancerNIHNational Cancer Institute2025$589,838January 10, 2025December 31, 2029AZAD, NILOFER S.reporter.nih.gov
3D Printed Engineered Living Materials for Drug DeliveryNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$588,952April 5, 2022December 31, 2025NELSON, ALSHAKIMreporter.nih.gov
Differential Wnt Dependencies in Colon Epithelium.NIHNational Cancer Institute2023 to 2025$588,612September 1, 2023August 31, 2028ENG, GEORGEreporter.nih.gov
Targeting regenerative reprogramming in colorectal cancerNIHNational Cancer Institute2024 to 2025$585,188September 1, 2024August 31, 2028ALONSO MARTINEZ, SALVADORreporter.nih.gov
Administrative Supplement: Autophagy mediated immune stimulation by reovirus in KRAS mutated colorectal cancerNIHNational Cancer Institute2022 to 2024$578,463January 14, 2022December 31, 2024MAITRA, RADHASHREEreporter.nih.gov
Let's Talk: Overcoming barriers to the uptake of cascade screening through a stakeholder-informed online interventionNIHNational Human Genome Research Institute2024$575,098September 20, 2024August 31, 2026ROBERTS, MEGAN C.reporter.nih.gov
Assessing feasibility of gastric cancer screening in the USNIHNational Cancer Institute2025$564,414April 1, 2025March 31, 2030KIM, MICHELLE KANGreporter.nih.gov
Immune control of oncogene selection in preneoplastic colonNIHNational Cancer Institute2023 to 2025$555,942September 14, 2023August 31, 2028MIRZA, HARISreporter.nih.gov
Bundled Multicancer Screening and Genetic Services Navigation to Improve Cancer OutcomesNIHNational Cancer Institute2025$547,047May 1, 2025April 30, 2030O'NEILL, SUZANNE C.reporter.nih.gov
Targeting iRhom to Improve Colon Cancer ImmunochemotherapyNIHNational Cancer Institute2025$546,625January 9, 2025December 31, 2029LI, SONGreporter.nih.gov
Functional Consequences of Racially Associated Ephrin Alterations on the Prostate Tumor MicroenvironmentNIHNational Cancer Institute2022 to 2024$538,243July 3, 2019June 30, 2025FRANCO CORONEL, OMARreporter.nih.gov
Role of innate immunity and the microbiome in colitis associated dysplasiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$536,536September 1, 2014April 30, 2027ABREU, MARIA TERESAreporter.nih.gov
Interaction between dietary taurine and microbiota sulfur metabolism in the development of colorectal cancerNIHNational Cancer Institute2025$536,489January 1, 2025December 31, 2029JOBIN, CHRISTIANreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Sloan-Kettering Inst Can ResearchNew York, NY21$41.4 million0$0
University of Michigan at Ann ArborAnn Arbor, MI22$38.2 million0$0
Mayo Clinic RochesterRochester, MN5$33.2 million0$0
University of TX MD Anderson Can CTRHouston, TX19$31.6 million0$0
Vanderbilt University Medical CenterNashville, TN13$29.9 million0$0
University of UtahSalt Lake City, UT12$28.2 million0$0
University of California, San FranciscoSan Francisco, CA16$27 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC13$25.9 million0$0
Fred Hutchinson Cancer CenterSeattle, WA12$25.1 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY3$23.9 million0$0
Stanford UniversityStanford, CA14$22 million0$0
Massachusetts General HospitalBoston, MA14$20.4 million0$0
Columbia University Health SciencesNew York, NY11$20.3 million0$0
Ohio State UniversityColumbus, OH12$20.2 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA10$18.9 million0$0
Ut Southwestern Medical CenterDallas, TX11$17.3 million0$0
University of PennsylvaniaPhiladelphia, PA10$16.7 million0$0
University of ChicagoChicago, IL15$15.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY12$15.6 million0$0
Washington UniversitySaint Louis, MO11$15.3 million0$0
Boston University Medical CampusBoston, MA3$14.9 million0$0
University of California, San DiegoLa Jolla, CA7$14.7 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA12$14 million0$0
Yale UniversityNew Haven, CT10$13.3 million0$0
Brigham and Women's HospitalBoston, MA6$12.7 million0$0
Indiana University IndianapolisIndianapolis, IN7$11 million0$0
Beckman Research Institute/city of HopeDuarte, CA6$10.9 million0$0
Boston Children's HospitalBoston, MA5$10 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY5$9.9 million0$0
Wake Forest University Health SciencesWinston-Salem, NC6$9.9 million0$0
University of ArizonaTucson, AZ8$9.9 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA4$9.6 million0$0
Kaiser Foundation Research InstituteOakland, CA4$9.6 million0$0
University of California Los AngelesLos Angeles, CA6$9.1 million0$0
Case Western Reserve UniversityCleveland, OH8$9.1 million0$0
University of MelbourneMelbourne1$9 million0$0
University of Alabama at BirminghamBirmingham, AL9$8.9 million0$0
Oregon Health & Science UniversityPortland, OR4$8.9 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH6$8.7 million0$0
University of WashingtonSeattle, WA7$8.7 million0$0
Northwestern University at ChicagoChicago, IL4$8.4 million0$0
University of Connecticut SCH of Med/dntFarmington, CT4$8.3 million0$0
Emory UniversityAtlanta, GA5$8.2 million0$0
Dana-Farber Cancer InstBoston, MA9$8.2 million0$0
University of Illinois at ChicagoChicago, IL4$8 million0$0
University of KentuckyLexington, KY7$8 million0$0
Dartmouth CollegeHanover, NH3$7.8 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA5$7.7 million0$0
SUNY at BuffaloAmherst, NY2$7.5 million0$0
University of Nebraska Medical CenterOmaha, NE6$7.4 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL5$7.3 million0$0
Johns Hopkins UniversityBaltimore, MD7$7.2 million0$0
University of Colorado DenverAurora, CO7$7.1 million0$0
University of South Carolina at ColumbiaColumbia, SC6$7 million0$0
ST. Jude Children's Research HospitalMemphis, TN2$6.5 million0$0
Harvard Medical SchoolBoston, MA7$6.2 million0$0
University of California-IrvineIrvine, CA5$6 million0$0
University of Wisconsin-MadisonMadison, WI3$5.8 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ5$5.4 million0$0
Vanderbilt UniversityNashville, TN3$5.3 million0$0
Medical University of South CarolinaCharleston, SC6$5.2 million0$0
Mayo Clinic ArizonaScottsdale, AZ2$5 million0$0
Georgetown UniversityWashington, DC3$4.8 million0$0
LSU Pennington Biomedical Research CTRBaton Rouge, LA2$4.8 million0$0
Westat, Inc.Bethesda, MD1$4.5 million0$0
New York University School of MedicineNew York, NY4$4.4 million0$0
University of IowaIowa City, IA2$4.3 million0$0
University of VirginiaCharlottesville, VA4$4.3 million0$0
Albert Einstein College of MedicineBronx, NY4$4.2 million0$0
Baylor College of MedicineHouston, TX3$4.2 million0$0
Therapyx, Inc.Buffalo, NY1$4 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA3$3.9 million0$0
Massachusetts Institute of TechnologyCambridge, MA4$3.8 million0$0
Columbus Community Clinical Oncology PRGColumbus, OH1$3.8 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY2$3.7 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL3$3.5 million0$0
Stingray Therapeutics, Inc.Houston, TX1$3.5 million0$0
Harvard UniversityCambridge, MA5$3.4 million0$0
University of HawaiiHonolulu, HI2$3.4 million0$0
Columbia UniversityNew York, NY2$3.4 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA3$3.3 million0$0
Georgia Tech Research CorporationAtlanta, GA2$3.3 million0$0
Michigan State UniversityEast Lansing, MI3$3.3 million0$0
Virginia Commonwealth UniversityRichmond, VA4$3.2 million0$0
Actuated Medical, Inc.Bellefonte, PA1$3.2 million0$0
Wayne State UniversityDetroit, MI1$3 million0$0
BCN Biosciences, LLCPasadena, CA1$3 million0$0
Texas A&m University Health Science CTRCollege Station, TX3$3 million0$0
Averto Medical INCFremont, CA2$3 million0$0
University of FloridaGainesville, FL3$2.9 million0$0
University of Southern CaliforniaLos Angeles, CA5$2.9 million0$0
Rockefeller UniversityNew York, NY3$2.8 million0$0
Augusta UniversityAugusta, GA3$2.7 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX4$2.6 million0$0
Louisiana State Univ HSC ShreveportShreveport, LA3$2.5 million0$0
Morehouse School of MedicineAtlanta, GA2$2.4 million0$0
Duke UniversityDurham, NC2$2.4 million0$0
Bobcatbio, Inc.Hummelstown, PA1$2.4 million0$0
Deep Creek Pharma, LLCYadkinville, NC2$2.4 million0$0
Digital Health Navigation Solutions, LLCWinston Salem, NC1$2.4 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025528$286,750,1910$0
2024569$275,131,2080$0
2023423$226,617,3380$0
2022296$167,947,5150$0
2021202$120,703,1850$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 17 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.393November 2, 2026Not listedSame assistance listing 93.393 as 159 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)PAR-25-095NIH93.393November 6, 2026$350,000Same assistance listing 93.393 as 159 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)PAR-25-096NIH93.393November 17, 2026$200,000Same assistance listing 93.393 as 159 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.393November 20, 2026Not listedSame assistance listing 93.393 as 159 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.393January 7, 2027$375,000Same assistance listing 93.393 as 159 awards here
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)PAR-25-069NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 159 awards here
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)PAR-25-070NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 159 awards here
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)PAR-25-081NIH93.393January 7, 2027$499,999Same assistance listing 93.393 as 159 awards here
Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)PAR-25-167NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 159 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.393January 15, 2027$350,000Same assistance listing 93.393 as 159 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.393January 25, 2027Not listedSame assistance listing 93.393 as 159 awards here
Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)RFA-CA-26-010NIH93.393January 25, 2027Not listedSame assistance listing 93.393 as 159 awards here
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)RFA-CA-28-013NIH93.393February 9, 2027$700,000Same assistance listing 93.393 as 159 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.393April 5, 2027Not listedSame assistance listing 93.393 as 159 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.393April 5, 2027Not listedSame assistance listing 93.393 as 159 awards here
Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)PAR-28-057NIH93.393May 25, 2027$500,000Same assistance listing 93.393 as 159 awards here
Implementation and Evaluation of Databases to Examine AIDSRFA-AI-28-025NIH93.393May 27, 2027Not listedSame assistance listing 93.393 as 159 awards here
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)PAR-25-210NIH93.393June 2, 2027Not listedSame assistance listing 93.393 as 159 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.