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Data / Research funding / Colo-Rectal Cancer

Colo-Rectal Cancer: 512 NIH awards ($373.9M) to 182 organizations

512 NIH awards ($373.9M) in the NIH spending category Colo-Rectal Cancer, to 182 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 512 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
UT Southwestern Medical Center Simmons Comprehensive Cancer CenterNIHNational Cancer Institute2021 to 2025$21,900,548September 1, 2010July 31, 2026ARTEAGA, CARLOS Lreporter.nih.gov
Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$19,528,719June 1, 1997June 30, 2028STEIDL, ULRICHreporter.nih.gov
Administrative Supplement for the NCI P30 CCSG to extend partnerships with comprehensive cancer control coalitions to study implementation of evidence-based cancer control interventionsNIHNational Cancer Institute2021$11,079,774January 1, 1997March 31, 2022LYNCH, THOMAS JAMESreporter.nih.gov
Statistical Methods for Integrative Genomics in CancerNIHNational Cancer Institute2021 to 2025$8,721,062July 1, 2016August 31, 2027GAUDERMAN, WILLIAM JAMESreporter.nih.gov
Base Title: PREVENT Preclinical Drug Development Program: Preclinical Efficacy and Intermediate Endpoint BiomarkersTask Order Title: Colorectal Cancer (CRC) Prevention by TPST-1495 in PIRC rat modNIHNational Cancer Institute2021 to 2023$7,628,615September 11, 2023September 10, 2026RAO, CHINTHALAPALLYreporter.nih.gov
The Cleveland Digestive Diseases Research Core Center (DDRCC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,425,666February 15, 2015August 31, 2030COMINELLI, FABIOreporter.nih.gov
Optimizing Colorectal Cancer Screening PREcision and Outcomes in CommunIty-baSEd Populations (PRECISE)NIHNational Cancer Institute2021 to 2023$6,108,355April 15, 2018March 31, 2025CORLEY, DOUGLAS ALLENreporter.nih.gov
CRC-HUB-SPOKE: A ColoRectal Cancer screening Hub for Southern California community health centers.NIHNational Cancer Institute2021 to 2023$4,080,149September 19, 2019August 31, 2025MARTINEZ, MARIA ELENAreporter.nih.gov
Smarter CRC Supplement for ACCSIS Patient NavigationNIHNational Cancer Institute2021 to 2023$3,328,541September 23, 2019August 31, 2025DAVIS, MELINDA MARIEreporter.nih.gov
Targeting 15-Prostaglandin Dehydrogenase (15-PGDH) in Cancer Risk, Prevention, and TreatmentNIHNational Cancer Institute2021 to 2023$2,814,960December 29, 2016November 30, 2023MARKOWITZ, SANFORD D.reporter.nih.gov
ACCISIS-ChicagoNIHNational Cancer Institute2021 to 2022$2,329,000September 21, 2018August 31, 2023KIM, KAREN Ereporter.nih.gov
PCPT and SELECT Cohorts: Core Infrastructure Support for Cancer ResearchNIHNational Cancer Institute2021 to 2023$2,327,659September 20, 2013July 31, 2025TANGEN, CATHERINE M.reporter.nih.gov
(ACCSIS) Accelerating Colorectal Cancer Screening through Implementation Science in AppalachiaNIHNational Cancer Institute2021 to 2022$2,310,722September 19, 2018March 31, 2025DIGNAN, MARK Breporter.nih.gov
Development and Validation of Prognostic Radiomic Markers of Response and Recurrence for Patients with Colorectal Liver MetastasesNIHNational Cancer Institute2021 to 2023$2,284,583March 1, 2019August 31, 2025DO, RICHARD KINH GIANreporter.nih.gov
Scaling Colorectal Cancer Screening Through Outreach, Referral, and Engagement (SCORE): A State-Level Program to Reduce Colorectal Cancer Burden in Vulnerable PopulationsNIHNational Cancer Institute2021 to 2023$2,126,299September 30, 2018August 31, 2024REULAND, DANIEL S.reporter.nih.gov
Reverse transcriptase inhibitor effects on the mobilome of colon cancerNIHNational Cancer Institute2021 to 2023$2,117,061July 1, 2019June 30, 2025TING, DAVID TSAIreporter.nih.gov
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasmaNIHNational Cancer Institute2021 to 2022$2,099,368July 15, 2019August 31, 2024COFFEY, ROBERT J.reporter.nih.gov
Treg-depleting immunotherapyNIHNational Cancer Institute2021 to 2022$2,000,000September 7, 2020September 30, 2024SUZDAK, PETER DAVIDreporter.nih.gov
Robust Predictor of Colon Cancer RiskNIHNational Cancer Institute2022 to 2023$1,999,992September 13, 2018July 31, 2025OSTRER, HARRYreporter.nih.gov
Development of SUMO1 small molecule degraders as the first-in-class anticancerdrugs for metastatic colorectal cancerNIHNational Cancer Institute2022 to 2023$1,999,119July 1, 2022June 30, 2025BELLAIL, ANITAreporter.nih.gov
Cancer Registry for Understanding and Improving Survivorship Experiences (CRUISE)NIHNational Cancer Institute2021 to 2023$1,936,037June 10, 2019May 31, 2025SARKAR, URMIMALAreporter.nih.gov
Disparities in access to and outcomes of cancer surgery for rural Medicare patientsNIHNational Cancer Institute2021 to 2023$1,929,880March 1, 2020February 28, 2025TOSTESON, ANNA N. A.reporter.nih.gov
Ultra-high content analyses of circulating and solid tumor cells: A diagnostic reference system for disease burdenNIHNational Cancer Institute2021 to 2023$1,913,568August 16, 2021August 31, 2025NEDERLOF, MICHELreporter.nih.gov
Metabolomic Strategies for Discovery and Validation of Biomarkers of Colorectal Cancer RecurrenceNIHNational Cancer Institute2021 to 2022$1,902,826April 1, 2017March 31, 2024ULRICH, CORNELIA Mreporter.nih.gov
Transcriptome-wide association study to identify susceptibility genes for colorectal cancerNIHNational Cancer Institute2021 to 2023$1,901,832September 4, 2018August 31, 2025GUO, XINGYIreporter.nih.gov
Biology of R-Spondin-Induced Sensitization to Asparaginase in Colorectal CancerNIHNational Cancer Institute2021 to 2023$1,889,937August 1, 2021July 21, 2024GUTIERREZ, ALEJANDROreporter.nih.gov
Nano-Engineered Lab-on-a-Chip for Assessing HuR-Regulated Exosomes for Cancer Monitoring and Targeted TherapyNIHNational Cancer Institute2021 to 2023$1,832,571May 16, 2019April 30, 2026XU, LIANGreporter.nih.gov
Development and Validation of a Measure of Organizational Readiness (motivation x capacity) for ImplementationNIHNational Cancer Institute2021 to 2023$1,817,941December 1, 2018November 30, 2025FERNANDEZ, MARIA EULALIAreporter.nih.gov
The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative ColitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,790,331February 1, 2021June 4, 2023SWANSON, GARTH Rreporter.nih.gov
The immune contexture of colorectal adenomas and serrated polypsNIHNational Cancer Institute2021 to 2023$1,762,921September 1, 2020August 31, 2025WALLACE, KRISTINreporter.nih.gov
Microsystems imaging system for epithelial-derived cancer heterogeneityNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,730,519September 1, 2019May 31, 2025WANG, THOMAS Dreporter.nih.gov
A Noninvasive Integrated Genomic Approach for Early Cancer Detection and Risk Stratification after TransplantationNIHNational Cancer Institute2021 to 2023$1,728,199March 1, 2019February 29, 2024KHUSH, KIRAN KAURreporter.nih.gov
Discovery of Small Molecule Ligands for PHD1 Reader Domain of Histone Demethylase KDM5ANIHNational Cancer Institute2021 to 2023$1,722,094July 1, 2020June 30, 2024FUJIMORI, DANICA GALONICreporter.nih.gov
Culturally Adapted Multilevel Decision Support Navigation Trial to Reduce Colorectal Cancer Disparity among At-Risk Asian American Primary Care PatientsNIHNational Institute on Minority Health and Health Disparities2021 to 2022$1,695,812September 26, 2017December 31, 2025LEE, SUNMINreporter.nih.gov
Molecular basis for dietary chemopreventionNIHNational Cancer Institute2021 to 2022$1,628,302March 1, 2016February 28, 2023CHAPKIN, ROBERT STEPHENreporter.nih.gov
DNA Methyltransferase Gene Expression in Colon CancerNIHNational Institute of Environmental Health Sciences2021 to 2023$1,625,091April 1, 1991February 28, 2025BAYLIN, STEPHEN B.reporter.nih.gov
The NYU Women's Health StudyNIHNational Cancer Institute2021 to 2023$1,621,115May 1, 2015April 30, 2025CHEN, YUreporter.nih.gov
Immunoprevention and immunosurveillance of human non-viral cancersNIHNational Cancer Institute2021 to 2022$1,608,806August 1, 2016July 31, 2023FINN, OLIVERA Jreporter.nih.gov
Three-Dimensional Multi-Parametric Ultrasound for Monitoring Therapy of Liver MetastasisNIHNational Cancer Institute2021 to 2023$1,604,984April 1, 2016February 29, 2024EL KAFFAS, AHMEDreporter.nih.gov
The miR-20/c-Myc/E2F Regulatory Axis is Critical for the Tumor Promoting Activity of Inflammatory Fibroblasts in Colitis-Associated CancerNIHNational Cancer Institute2021 to 2023$1,582,909March 1, 2019August 31, 2025HUANG, EMINA HUI-NAreporter.nih.gov
Post-polypectomy Surveillance for Reducing Colon Cancer Incidence and MortalityNIHNational Cancer Institute2021 to 2023$1,569,749February 1, 2018December 31, 2024GUPTA, SAMIRreporter.nih.gov
SMAD4 regulation of colon epithelial cell inflammatory responsesNIHNational Cancer Institute2021 to 2023$1,533,094July 1, 2019June 30, 2024MEANS, ANNA Lreporter.nih.gov
Exosomal Biomarkers for the Noninvasive Detection of Colorectal CancerNIHNational Cancer Institute2021 to 2023$1,510,680August 20, 2019July 31, 2025GOEL, AJAYreporter.nih.gov
SurvivorCare: A digital health solution to support long-term cancer survivorship using patient navigationNIHNational Cancer Institute2021 to 2022$1,501,567September 21, 2021August 31, 2024HO, Y. XIANreporter.nih.gov
Point of care, real-time urine metabolomics test to diagnose colorectal cancers and polyps in low- and middle-income countriesNIHNational Cancer Institute2021 to 2022$1,491,465April 15, 2017April 30, 2024KINGHAM, T PETERreporter.nih.gov
Coordinating Center for Population-based Research to Optimize Cancer Screening (PROSPR) (U24)NIHNational Cancer Institute2022 to 2023$1,464,869April 15, 2018March 31, 2026LI, CHRISTOPHER Ireporter.nih.gov
Neoantigen Vaccination for Lynch Syndrome ImmunopreventionNIHNational Cancer Institute2021 to 2022$1,418,370September 30, 2018August 31, 2024LIPKIN, STEVEN Mreporter.nih.gov
Prediciting and addressing colonoscopy non-adherence in community settingsNIHNational Cancer Institute2021 to 2022$1,403,333April 1, 2018March 31, 2024CORONADO, GLORIA Dreporter.nih.gov
Drug-Loaded Nanobubbles for Ultrasound Enhanced Delivery to Colon Cancer Liver MetastasisNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,397,305September 30, 2019June 30, 2025EXNER, AGATA Areporter.nih.gov
A Fragment-Based Strategy for K-RAS Covalent InhibitorsNIHNational Cancer Institute2021 to 2023$1,388,881July 2, 2021March 1, 2024MEROUEH, SAMYreporter.nih.gov
Determining the risk factor profile and biology of colorectal cancer in NigeriaNIHNational Cancer Institute2021 to 2023$1,386,615August 1, 2020April 30, 2025KINGHAM, T PETERreporter.nih.gov
Addressing the Biology of Health Disparities by Targeting Geographical Ancestry-driven Variants of ImmunityNIHNational Institute on Minority Health and Health Disparities2021 to 2022$1,381,253September 20, 2021July 7, 2023KIMBRO, KEVIN SEANreporter.nih.gov
A Chemical Genetic Approach to Exploring Novel Therapeutic Space for Colorectal CancerNIHNational Cancer Institute2021 to 2023$1,377,857March 1, 2021May 31, 2023DAR, ARVINreporter.nih.gov
Tissue-specific genetic interactions in cancerNIHNational Cancer Institute2021 to 2022$1,375,018June 20, 2018May 31, 2024HAIGIS, KEVINreporter.nih.gov
Preclinical validation of oral therapeutic lead proteins targeting epithelial GM1 ganglioside for ulcerative colitis therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,370,301June 20, 2020March 31, 2026MATOBA, NOBUYUKIreporter.nih.gov
KanSurvive: Testing a model for improving cancer survivorship care in rural practiceNIHNational Cancer Institute2021 to 2023$1,358,381August 23, 2019July 31, 2025KLEMP, JENNIFER ROSEreporter.nih.gov
Microbiome-triggered reprogramming and mutation of colon epithelial cells leading to tumor stem-like cellsNIHNational Cancer Institute2021 to 2023$1,358,184April 1, 2019March 31, 2025HUYCKE, MARK Mreporter.nih.gov
Self-immolative prodrug/miRNA nanoparticle combinations for cancer treatmentNIHNational Cancer Institute2021 to 2023$1,351,610February 11, 2019January 31, 2026OUPICKY, DAVIDreporter.nih.gov
MDACC-PREDICTNIHNational Cancer Institute2021 to 2022$1,327,977September 1, 2020August 31, 2025MANNING, HENRY CHARLESreporter.nih.gov
Longitudinal therapeutic monitoring of colorectal cancer patients using exosome-based liquid biopsiesNIHNational Cancer Institute2021 to 2022$1,314,717July 1, 2018June 30, 2024MAITRA, ANIRBANreporter.nih.gov
Promoting follow-up of abnormal cancer screening tests using population-basedsystems to support stepped care multilevel interventionNIHNational Cancer Institute2021 to 2022$1,305,011September 30, 2018August 31, 2024HAAS, JENNIFER Sreporter.nih.gov
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersNIHNational Institute of General Medical Sciences2021 to 2023$1,295,118January 1, 2020December 31, 2025VO-DINH, TUANreporter.nih.gov
Ultrabright Theranostic SERRS Nanoparticles for Gastrointestinal EndoscopyNIHNational Cancer Institute2022 to 2023$1,275,697February 1, 2018May 31, 2025ROGALLA, STEPHANreporter.nih.gov
SREBP-Mediated Regulation of Intestinal Epithelial HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,268,460August 1, 2019May 31, 2025ENGELKING, LUKE JAMESreporter.nih.gov
LFA-9 (mPGES-1/5-LOX Inhibitor): Preclinical Studies to Support a Clinical Trial,NIHNational Cancer Institute2021 to 2023$1,262,892September 17, 2018March 16, 2024MCCORMICK, DAVIDreporter.nih.gov
Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustionNIHNational Cancer Institute2021 to 2023$1,259,518August 1, 2019July 31, 2025YI, QINGreporter.nih.gov
Integrative Single-Cell Atlas of Host and Microenvironment in Colorectal Neoplastic TransformationNIHNational Cancer Institute2021 to 2023$1,252,480May 1, 2023August 31, 2024COFFEY, ROBERT J.reporter.nih.gov
Microvasculature in Colon Field Carcinogenesis: Clinical-Biological ImplicationsNIHNational Cancer Institute2021 to 2022$1,244,763March 5, 2018February 28, 2025ROY, HEMANT K.reporter.nih.gov
Three dimensional nanoscale nuclear architecture mapping based taxonomy of precursor lesions for predicting colorectal cancer riskNIHNational Cancer Institute2021 to 2023$1,240,003April 1, 2019March 31, 2025UTTAM, SHIKHARreporter.nih.gov
Reducing Cancer Transcriptional Heterogeneity through Regulation of Chromatin StructureNIHNational Cancer Institute2021 to 2022$1,239,236April 9, 2018March 31, 2025BACKMAN, VADIMreporter.nih.gov
Bacterial correlates of colorectal cancer subgroups and survivalNIHNational Cancer Institute2021 to 2022$1,231,902September 1, 2018August 31, 2025PHIPPS, AMANDA IRENEreporter.nih.gov
Investigating Amino Acid Depletion in the Tumor Microenvironment as a Metabolic Immune CheckpointNIHNational Cancer Institute2021 to 2023$1,229,239December 2, 2020November 30, 2023THOMPSON, CRAIG Breporter.nih.gov
Rational translation of gold nanoparticle mediated radiosensitization tothe clinicNIHNational Cancer Institute2021 to 2022$1,222,438January 13, 2021September 5, 2022KRISHNAN, SUNILreporter.nih.gov
Genetic and Dietary Interactions in MMR Deficient Colon TumorigenesisNIHNational Cancer Institute2021 to 2022$1,203,660July 5, 2018May 31, 2024AUGENLICHT, LEONARD Hreporter.nih.gov
Statistical Methods for Analysis of Tumor Heterogeneity in Genetic EpidemiologyNIHNational Cancer Institute2021 to 2023$1,166,626July 1, 2015June 30, 2025HSU, LIreporter.nih.gov
Elucidating the Role of MALAT1 Somatic Driver Mutations in Colorectal CancerNIHNational Cancer Institute2021 to 2023$1,147,685December 4, 2018November 30, 2024LIPKIN, STEVEN Mreporter.nih.gov
Epigenomic Reprogramming in Patient Derived Models of Colorectal CancerNIHNational Cancer Institute2021 to 2022$1,141,487September 1, 2018August 31, 2024HSU, SHIAOWEN DAVIDreporter.nih.gov
D3-creatine dilution to determine skeletal muscle mass in colon cancer patientsNIHNational Cancer Institute2021 to 2023$1,136,772February 1, 2020January 31, 2025FELICIANO, ELIZABETH MARJORIE CESPEDESreporter.nih.gov
Role of the microbiota in DNA methylation and CRC developmentNIHNational Cancer Institute2021 to 2022$1,135,049December 15, 2017November 30, 2023ISSA, JEAN-PIERRE J.reporter.nih.gov
Detection of somatic, subclonal and mosaic CNVs from sequencingNIHNational Cancer Institute2021 to 2022$1,134,197May 1, 2018April 30, 2024ABYZOV, ALEXEJreporter.nih.gov
Carbohydrate Structure Controls on Human Gut Microbial EcologyNIHNational Institute of General Medical Sciences2021 to 2023$1,127,763August 9, 2019June 30, 2025LINDEMANN, STEPHEN ROBERTreporter.nih.gov
Development and Mechanistic Studies of an Engineered Human Enzyme to Abrogate Immune Suppression due to Elevated Methylthioadenosine (MTA) by MTAP null/low TumorsNIHNational Cancer Institute2021 to 2023$1,119,912July 1, 2019June 30, 2025STONE, EVERETTreporter.nih.gov
A Case-Control Study to Evaluate Broad-Spectrum Antibiotic use and High Birth Weight as Potential Risk Factors for Early-Onset Colorectal CancerNIHNational Cancer Institute2021 to 2023$1,102,454September 15, 2021August 31, 2025CHAO, CHUN R.reporter.nih.gov
CXCR4 as a target for colon cancer chemopreventionNIHNational Cancer Institute2021 to 2023$1,083,245July 1, 2019June 30, 2024BISSONNETTE, BRUCE MARCreporter.nih.gov
CCAR2 as a Target for Prevention of Colorectal Cancer.NIHNational Cancer Institute2021 to 2023$1,080,815April 1, 2008February 28, 2025DASHWOOD, RODERICK Hreporter.nih.gov
Regulation of Necroptosis and inflammationNIHNational Cancer Institute2021 to 2023$1,076,589January 1, 2019December 31, 2023LOU, ZHENKUNreporter.nih.gov
Enhancing Prevention Pathways Towards Tribal Colorectal HealthNIHNational Cancer Institute2021 to 2022$1,073,429April 1, 2016June 30, 2024MISHRA, SHIRAZ I.reporter.nih.gov
DOTA-based pre-targeting of alpha emittersNIHNational Cancer Institute2022 to 2023$1,071,344December 10, 2018November 30, 2024CHEAL, SARAH MARIEreporter.nih.gov
Defining Mechanisms of Transformation Driven By the Zinc Finger Transcription Factor PLAGL2 in the Intestinal EpitheliumNIHNational Cancer Institute2021 to 2023$1,066,433April 1, 2019March 31, 2025RUBIN, DEBORAH C.reporter.nih.gov
Wnt Signaling in intestinal stem cells, homeostasis, and cancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,042,786August 20, 2019May 31, 2024HE, XIreporter.nih.gov
SUPPORT SERVICES FOR THE PLCO ETIOLOGIC&EARLY MARKER STUDIES (PLCO EEMS)NIHNational Cancer Institute2021$1,024,263July 20, 2020July 19, 2021RILEY, THOMASreporter.nih.gov
Mechanisms and Correction of Abnormal Bicarbonate Secretion by DRA in DiarrheaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,021,334February 5, 2019May 31, 2024TSE, CHUNG-MINGreporter.nih.gov
DKK2 regulates NK activation and tumor immunityNIHNational Cancer Institute2021 to 2022$1,016,358December 1, 2017December 31, 2023WU, DIANQINGreporter.nih.gov
Early Prediction of Tumor Response to Treatment: Clinical Translation of [99mTc]-DuramycinNIHNational Cancer Institute2021 to 2022$1,015,350February 1, 2019January 31, 2025PAK, KOON Yreporter.nih.gov
The function of lysophosphatidic acid receptor LPA5R in intestinal inflammation and epithelial damageNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,014,004September 20, 2018May 31, 2024YUN, CHANGHYON CHRISreporter.nih.gov
Illuminating the evolutionary history of colorectal cancer metastasis: basic principles and clinical applicNIHNational Cancer Institute2021 to 2023$1,005,583June 1, 2023August 31, 2023NAXEROVA, KAMILAreporter.nih.gov
Active Disposable Cap for Endoscope Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile PolypsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$999,979August 7, 2018December 31, 2022MULVIHILL, MAUREEN L.reporter.nih.gov
Imaging nanoscale chromatin folding in early carcinogenesisNIHNational Cancer Institute2021 to 2023$996,716August 1, 2020December 31, 2023LIU, YANGreporter.nih.gov
Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid TumorsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$989,015August 21, 2018May 31, 2024TONG, SHENGreporter.nih.gov
Nutritionally Driven Sporadic Intestinal Tumors: Impact on Stem CellsNIHNational Cancer Institute2021 to 2022$976,612July 5, 2018May 31, 2024AUGENLICHT, LEONARD Hreporter.nih.gov
The role of Interleukin 17RB signaling in colorectal cancer progressionNIHNational Cancer Institute2021 to 2022$947,522July 1, 2021June 30, 2023GRIVENNIKOV, SERGEI Ireporter.nih.gov
Accelerating Transdisciplinary Epidemiology of Colorectal CancerNIHNational Cancer Institute2021$931,108August 1, 2019July 31, 2022OGINO, SHUJIreporter.nih.gov
Translation addiction and targeting in colon cancerNIHNational Cancer Institute2021 to 2022$928,987January 1, 2018March 31, 2023YU, JIANreporter.nih.gov
Combined NGS tumor-based detection of germline Lynch syndrome mutations and prognostic classification of endometrial cancersNIHNational Cancer Institute2021 to 2022$925,110July 6, 2018June 30, 2024GOODFELLOW, PAUL JOSEPHreporter.nih.gov
DOTA-based pre-targeting of alpha emittersNIHNational Cancer Institute2021 to 2022$918,123December 10, 2018December 31, 2021CHEAL, SARAH MARIEreporter.nih.gov
Multiscale systems biology modeling to exploit tumor-stromal metabolic crosstalk in colorectal cancerNIHNational Cancer Institute2021 to 2022$917,725September 13, 2018August 31, 2024FINLEY, STACEY DELERIAreporter.nih.gov
Mechanisms of cytokine driven tumor elicited inflammation in colorectal cancerNIHNational Cancer Institute2021 to 2022$912,962September 1, 2020August 31, 2024GRIVENNIKOV, SERGEI Ireporter.nih.gov
(PQ1) Adaptive immune and microbial mechanisms regulating Lynch syndrome penetranceNIHNational Cancer Institute2021 to 2022$911,675September 4, 2018August 31, 2024LIPKIN, STEVEN Mreporter.nih.gov
Development and validation of clinical prediction models for the use and interpretation of multigene hereditary cancer risk assessmentNIHNational Cancer Institute2021 to 2022$901,778September 30, 2008January 31, 2025SYNGAL, SAPNAreporter.nih.gov
Metabolic regulation of intestinal stem cell homeostasisNIHNational Cancer Institute2021 to 2022$900,942July 1, 2018June 30, 2024RUTTER, JARED Preporter.nih.gov
Early life exposures and risk of young-onset colorectal cancerNIHNational Cancer Institute2021 to 2023$892,717September 1, 2021August 31, 2025MURPHY, CAITLIN Creporter.nih.gov
Gain-of-function mutant p53 and metabolic reprogramming in colorectal cancerNIHNational Cancer Institute2021 to 2022$890,528April 1, 2021March 31, 2023HU, WENWEIreporter.nih.gov
Theory and methods for mediation and interactionNIHNational Cancer Institute2021 to 2022$885,392February 19, 2018January 31, 2025VANDERWEELE, TYLERreporter.nih.gov
Role of necroptosis in colorectal cancer therapyNIHNational Cancer Institute2021 to 2022$882,531June 1, 2019May 31, 2023ZHANG, LINreporter.nih.gov
Liver Cancer Therapy by MiR-22 and Its InducersNIHNational Cancer Institute2021 to 2023$876,644February 1, 2018January 31, 2025WAN, YU-JUI YVONNEreporter.nih.gov
A microengineered colon cancer-chip designed to investigate tumor-stromal interactions driving cancer progressionNIHNational Cancer Institute2021$875,151December 1, 2020November 30, 2021MUMENTHALER, SHANNON MICHELLEreporter.nih.gov
Targeting defective necroptosis in colorectal cancerNIHNational Cancer Institute2021 to 2022$874,071December 1, 2019November 30, 2024ZHANG, LINreporter.nih.gov
Using Natural Language Processing and Crowdsourcing to Monitor and Evaluate Public Information and Communication Disparities about Colon Cancer ScreeningNIHNational Cancer Institute2021 to 2022$867,795April 15, 2021June 30, 2022KING, ANDY Jreporter.nih.gov
The role of cell-specific TLR-4 signaling in oxaliplatin-induced peripheral neuropathyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$864,952September 15, 2018June 30, 2025WHITE, FLETCHER Areporter.nih.gov
Development of a Dual and Selective Small Molecule Inhibitor of EGFR and PI3 Kinase to Treat BRAF Mutant Colorectal CancerNIHNational Cancer Institute2021 to 2022$863,904April 17, 2018March 31, 2024LEOPOLD, JUDITH Sreporter.nih.gov
Massively parallel experimental measurement of variant functional impactsNIHNational Institute of General Medical Sciences2021 to 2022$861,644August 6, 2018May 31, 2024KITZMAN, JACOB OTTOreporter.nih.gov
Role of Bacteria in Colitis-Associated Colon CancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$858,754April 1, 2007April 30, 2025JOBIN, CHRISTIANreporter.nih.gov
Phase 1 Study of DNX-2440 for Resectable Colorectal Liver Metastasis - IND 018569NIHNational Cancer Institute2022$852,568September 1, 2022August 31, 2024ROBBINS, JOAN MARIEreporter.nih.gov
2/2 VSU-MCC Partnership for Cancer Disparities Research and Training program (SUCCEED)NIHNational Cancer Institute2021 to 2024$843,034September 20, 2021August 31, 2025FAISON, MILTON Oreporter.nih.gov
Physical Signaling Mechanisms That Regulate Intestinal ArchitectureNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$836,190May 19, 2020April 30, 2024PACK, MICHAEL Areporter.nih.gov
Activating p53 for colorectal cancer preventionNIHNational Cancer Institute2021 to 2023$833,467June 12, 2018May 31, 2024WU, XIANGWEIreporter.nih.gov
The regulation of mutant p53 protein accumulation in cancer: molecular basis and therapeutic potentialNIHNational Cancer Institute2021 to 2022$823,103July 1, 2021June 30, 2023FENG, ZHAOHUIreporter.nih.gov
High Mobility Group A1 Chromatin Regulators in Colon CarcinogenesisNIHNational Cancer Institute2021 to 2022$820,336July 24, 2018June 30, 2025RESAR, LINDA M Sreporter.nih.gov
Methods for Analyzing Cancer Somatic Mutation DataNIHNational Cancer Institute2021 to 2022$805,199September 20, 2018August 31, 2025HE, QIANCHUANreporter.nih.gov
Understanding NLRP6 function in intestinal homeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$800,348July 1, 2019April 30, 2023CHEN, GRACE Y.reporter.nih.gov
Sex specific epigenetic regulation of colon cancer metastasisNIHNational Cancer Institute2022 to 2023$799,225September 6, 2022August 31, 2028WANG, Y. ALANreporter.nih.gov
BET degraders for improving colorectal cancer therapyNIHNational Cancer Institute2021 to 2022$797,550April 1, 2021March 31, 2026ZHANG, LINreporter.nih.gov
Understanding the full spectrum of epigenetic vulnerability in cancer through the delineation of DNA methylation function in gene 3' endNIHNational Cancer Institute2021 to 2022$790,332February 1, 2019December 30, 2022TING, ANGELA Hreporter.nih.gov
Resistance Training to Reduce Chemotoxicity in Colon CancerNIHNational Cancer Institute2021$788,917June 15, 2017May 31, 2024CAAN, BETTE Jreporter.nih.gov
Colorectal Cancer Molecular Subtype Assay Development and ValidationNIHNational Cancer Institute2021 to 2023$787,854September 21, 2018August 31, 2025MARU, DIPEN M.reporter.nih.gov
Enterotoxigenic B. fragilis Acquisition in Disease SusceptibilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$787,500September 13, 2018August 31, 2024BUBECK WARDENBURG, JULIANEreporter.nih.gov
Cell-specific nanocarrier with endocytic and endosomolytic activities for therapeutic genome editingNIHNational Center for Advancing Translational Sciences2021$784,845August 22, 2019November 30, 2022LAM, KIT Sreporter.nih.gov
Progression, response, and resistance of RSPO fusion colorectal cancerNIHNational Cancer Institute2021 to 2022$760,809August 1, 2018July 31, 2023DOW, LUKAS EDWARDreporter.nih.gov
Extreme High Throughput Screening Via Massively Parallel Droplet Dispenser ArraysNIHNational Institute of General Medical Sciences2021 to 2022$754,805September 23, 2019August 31, 2024HUI, ELLIOT Ereporter.nih.gov
Scalable Clinical Decision Support for Individualized Cancer Risk ManagementNIHNational Cancer Institute2021$749,164August 1, 2017December 31, 2022DEL FIOL, GUILHERMEreporter.nih.gov
Targeting Cancer through Suppressing Stress Induction of GRP78/BiPNIHNational Cancer Institute2021 to 2022$747,327December 1, 2019November 30, 2023LEE, AMY Sreporter.nih.gov
Malignant Cell Engagement in Immune Circuits of Human Microsatellite-stable and Microsatellite-instable Colorectal CancerNIHNational Cancer Institute2021 to 2023$747,000April 8, 2021August 31, 2024PELKA, KARINreporter.nih.gov
Genetics and Biology of Metastatic Colorectal CancerNIHNational Cancer Institute2021 to 2022$746,515September 1, 2018August 31, 2023DEPINHO, RONALD ANTHONYreporter.nih.gov
Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal CancerNIHNational Cancer Institute2021 to 2022$746,393August 14, 2018July 31, 2024MANI, SRIDHARreporter.nih.gov
Coordinating Center for Population-based Research to Optimize Cancer Screening (PROSPR) (U24)NIHNational Cancer Institute2021$743,093April 15, 2018March 31, 2022LI, CHRISTOPHER Ireporter.nih.gov
(PQ4) - Tools for simultaneous disruption of multiple epigenetically silenced genes for studying their roles in tumorigenesis using ex vivo human and mouse colon organoid and in vivo mouse modelsNIHNational Cancer Institute2021 to 2022$741,665September 1, 2018August 31, 2024EASWARAN, HARIHARANreporter.nih.gov
Colonic responses to vitamin D and aspirin in African- and European-AmericansNIHNational Cancer Institute2021 to 2022$734,655July 3, 2018June 30, 2024KUPFER, SONIAreporter.nih.gov
Effectiveness and Implementation of mPATH-CRC: a Mobile Health System for Colorectal Cancer ScreeningNIHNational Cancer Institute2021 to 2022$734,252April 1, 2018March 31, 2024MILLER, DAVID Preporter.nih.gov
Targeted Nanomedicines with Synergistic Chemotherapeutics to Enhance Immunotherapy of Metastatic Colorectal CancerNIHNational Cancer Institute2021 to 2022$732,118July 1, 2018June 30, 2023LIN, WENBINreporter.nih.gov
Immunologic aspects of targeted therapy of erbB tumorsNIHNational Cancer Institute2021 to 2022$729,210April 1, 2018January 31, 2025GREENE, MARK Ireporter.nih.gov
Dietary Carcinogens for Colorectal CancerNIHNational Cancer Institute2021 to 2022$724,680October 16, 2019May 31, 2023LI, YONGreporter.nih.gov
The role of gene enhancer elements in colon cancerNIHNational Cancer Institute2021 to 2023$724,672April 1, 2012December 31, 2023TESAR, PAUL JOSEPHreporter.nih.gov
Mechanisms of lincDUSP Oncogenic Effects in Colon CancerNIHNational Cancer Institute2022 to 2023$721,844September 1, 2018August 31, 2025LAFRAMBOISE, THOMAS LOUISreporter.nih.gov
Improving Colorectal Cancer Screening and Risk Assessment through Deep Learning on Medical Images and RecordsNIHNational Library of Medicine2021 to 2022$713,400February 12, 2019January 31, 2024HASSANPOUR, SAEEDreporter.nih.gov
Exosomes and platinum-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2022$709,918July 1, 2018June 30, 2024ZHANG, ZHENG GANGreporter.nih.gov
The Functional Role of GRM3 in Colon CancerNIHNational Cancer Institute2021 to 2022$706,563March 14, 2017January 31, 2024WANG, JINGreporter.nih.gov
The Functional Role of LGR5 in Colon CancerNIHNational Cancer Institute2021 to 2022$706,563April 1, 2017January 31, 2024WANG, JINGreporter.nih.gov
Impact of germline variants on racial and ethnic differences in somatic mutation frequencyNIHNational Cancer Institute2021 to 2022$706,563March 1, 2018February 29, 2024TOLAND, AMANDA EWARTreporter.nih.gov
Mechanisms and therapeutic targeting of colon cancer stem cell plasticityNIHNational Cancer Institute2021 to 2022$704,550April 1, 2018March 31, 2025CARMON, KENDRA S.reporter.nih.gov
Oxalobacter formigenes-derived Factors Impact Hyperoxalemia, Hyperoxaluria, and Related Kidney StonesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$699,600January 1, 2022December 31, 2025HASSAN, HATIM Areporter.nih.gov
Molecular targeting the translational control axis in Wnt/beta-catenin signaling pathwayNIHNational Cancer Institute2021 to 2022$696,807August 1, 2017July 31, 2024ZHANG, JIAN-TINGreporter.nih.gov
Inactivation of MSH3 in Colorectal Cancer and RaceNIHNational Cancer Institute2021 to 2022$696,131August 1, 2021January 15, 2023CARETHERS, JOHN Mreporter.nih.gov
Role of Sulfiredoxin in Colorectal Cancer DevelopmentNIHNational Cancer Institute2021 to 2022$692,826January 1, 2018December 31, 2023WEI, QIOUreporter.nih.gov
Systems approaches to understanding the relationships between genotype, signaling, and therapeutic efficacyNIHNational Cancer Institute2021$679,295April 5, 2017March 31, 2022LAUFFENBURGER, DOUGLAS Areporter.nih.gov
Tumor-Associated Antigen Delivery using Protein Nanoparticles for Combined ImmunotherapyNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$667,636April 1, 2019December 31, 2024WANG, SZU-WENreporter.nih.gov
Aggressive colorectal cancer subtypes and social disadvantage in a racially diverse cohortNIHNational Cancer Institute2021 to 2022$655,223June 1, 2021July 31, 2022ROZEK, LAURAreporter.nih.gov
Longitudinal Adherence to Colorectal Cancer Screening in the VANIHNational Cancer Institute2021 to 2023$653,681April 1, 2019March 31, 2025LIANG, PETER SHUANGreporter.nih.gov
PCPT and SELECT Cohorts: Core Infrastructure Support for Cancer ResearchNIHNational Cancer Institute2021$653,163September 20, 2013March 31, 2022TANGEN, CATHERINE M.reporter.nih.gov
Development of novel metastatic mouse models that recapitulate the major immune contexts of human colon cancerNIHNational Cancer Institute2021 to 2022$650,862December 1, 2019November 30, 2022JACKS, TYLER E.reporter.nih.gov
Targeted Hyperpolarized Molecular Beacons for Colorectal Cancer DetectionNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$648,000September 30, 2021July 31, 2025BHATTACHARYA, PRATIP K.reporter.nih.gov
Systems Modeling of Tumor Heterogeneity and Therapy Response in Colorectal CancerNIHNational Cancer Institute2021$645,756June 1, 2017May 31, 2023GINTY, FIONAreporter.nih.gov
A patient-centered intervention using virtual technology to reduce colorectal cancer disparities in primary careNIHNational Cancer Institute2021$639,261February 1, 2017January 31, 2024LOK, BENJAMINreporter.nih.gov
Uncovering Roles of Metabolites in Colorectal Cancer EtiologyNIHNational Cancer Institute2021 to 2022$639,201August 1, 2020June 30, 2024SHU, XIANGreporter.nih.gov
Implementing Universal Lynch Syndrome Screening across Multiple Healthcare Systems: Identifying Strategies to Facilitate and Maintain Programs in Different Organizational ContextsNIHNational Cancer Institute2021$637,674August 1, 2017July 31, 2023RAHM, ALANNA Kreporter.nih.gov
Great Lakes New England Clinical Validation CenterNIHNational Cancer Institute2021$627,186May 15, 2000August 31, 2022BRENNER, DEAN E.reporter.nih.gov
Comparative Effectiveness of Fecal Immunochemical Tests with Optical ColonoscopyNIHNational Cancer Institute2021$623,145August 1, 2017June 30, 2023LEVY, BARCEY THURSTONreporter.nih.gov
Precision therapeutics of inflammatory bowel disease guided by Boolean logicNIHNational Center for Advancing Translational Sciences2021 to 2022$621,778August 28, 2020July 31, 2023SAHOO, DEBASHISreporter.nih.gov
Novel Strategies for Intervention of Inflammatory Diseases and CancerNIHNational Cancer Institute2021 to 2022$620,730July 1, 2004May 31, 2025WANG, RONGFUreporter.nih.gov
CLINCIAL VALIDATION OF APC AND TP53 AS BIOMARKERS FOR CETUXIMAB RESPONSENIHNational Cancer Institute2021 to 2022$607,571July 3, 2019March 31, 2023YEATMAN, TIMOTHY Jreporter.nih.gov
Safer Approaches to CRC ChemopreventionNIHNational Cancer Institute2021$607,251December 15, 2016November 30, 2023RAO, CHINTHALAPALLY V.reporter.nih.gov
Global Measurements of Protein Folding Stability for Characterization of Aging and DiseaseNIHNational Institute of General Medical Sciences2021 to 2022$605,750September 23, 2019August 31, 2023FITZGERALD, MICHAEL Creporter.nih.gov
Novel Path to Chronic Sensorimotor Dysfunction and Treatment for ChemotherapyNIHNational Cancer Institute2021 to 2022$604,292September 13, 2018July 31, 2024COPE, TIMOTHY Creporter.nih.gov
Development of 5hmC and 5mC biomarkers in cell-free circulating DNA for sensitive colon cancer detection and prognosisNIHNational Cancer Institute2021$599,788August 1, 2017July 31, 2023BISSONNETTE, BRUCE MARCreporter.nih.gov
Advanced Point-scanning Confocal Microscope for a Microscopy Core FacilityNIHOffice of the Director, National Institutes of Health2023$599,488September 15, 2023September 14, 2024AGUIRRE-GHISO, JULIO A.reporter.nih.gov
Randomized Controlled Trial of Resistant Starch to Reduce Colon Cancer Risk in Alaska Native PeopleNIHNational Cancer Institute2021$596,049January 10, 2017December 31, 2022O'KEEFE, STEPHEN J.D.reporter.nih.gov
Targeting Wnt-dependent colorectal cancerNIHNational Cancer Institute2021 to 2022$594,046August 12, 2021February 29, 2024ROBBINS, DAVID Jreporter.nih.gov
A Major Nutritional Effect on Intestinal Stem Cells and TumorsNIHNational Cancer Institute2021 to 2022$582,164July 17, 2018May 31, 2024AUGENLICHT, LEONARD Hreporter.nih.gov
Targeting VISTA eradicates large, established PD-1/CTLA-4 resistant tumorsNIHNational Cancer Institute2021$570,047May 1, 2017April 30, 2023NOELLE, RANDOLPH J.reporter.nih.gov
Paid Sick Leave Mandates and Cancer PreventionNIHNational Cancer Institute2021 to 2022$560,463August 5, 2019July 31, 2024CALLISON, KEVINreporter.nih.gov
Health care system-led familial risk notification: design and ethical assessmentNIHNational Human Genome Research Institute2021 to 2023$559,616September 20, 2018June 30, 2024BLASI, PAULA RAEreporter.nih.gov
Task Order: Colorectal Cancer Prevention by a Novel EPA Analogue TP-252 and Naproxen in FAP and lynch syndrome modelsNIHNational Cancer Institute2021$554,176September 15, 2019February 14, 2022KENNEDY, GREGORYreporter.nih.gov
Sulindac sensitizes colorectal cancer to anti-PD-L1 therapyNIHNational Cancer Institute2022$553,817August 15, 2022July 31, 2023XI, YAGUANGreporter.nih.gov
STING-Activating Polymeric Nanovaccines for T Cell Therapy of MelanomaNIHNational Cancer Institute2021$535,530September 30, 2017August 31, 2022GAO, JINMINGreporter.nih.gov
Developing an intervention to improve follow-up of abnormal fecal immunochemical test results in a safety-net population using a mixed methods approachNIHNational Cancer Institute2021 to 2023$534,394September 1, 2019March 31, 2025ISSAKA, RACHEL B.reporter.nih.gov
Functional Consequences of Racially Associated Ephrin Alterations on the Prostate Tumor MicroenvironmentNIHNational Cancer Institute2021 to 2022$530,308July 3, 2019October 31, 2022FRANCO CORONEL, OMARreporter.nih.gov
An organotypic model recapitulating colon cancer microenvironment and metastasisNIHNational Cancer Institute2021$521,870September 25, 2017August 30, 2024HUANG, EMINA HUI-NAreporter.nih.gov
Harnessing the CRL4 ubiquitin ligase for antagonizing colorectal carcinogenesisNIHNational Cancer Institute2021$517,885January 17, 2017December 31, 2023ZHOU, PENGBOreporter.nih.gov
Novel Mcl-1 inhibitors for overcoming therapeutic resistance in colorectal cancerNIHNational Cancer Institute2021$516,652June 5, 2017May 31, 2023NIKOLOVSKA-COLESKA, ZANETAreporter.nih.gov
Investigating L1CAM-dependent stem cell regeneration in metastasisNIHNational Cancer Institute2021 to 2022$513,638August 13, 2018July 31, 2023GANESH, KARUNAreporter.nih.gov
Validation of blood-based predictive biomarkers of therapeutic response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancerNIHNational Cancer Institute2022 to 2023$511,837May 1, 2022April 30, 2024ARORA, SANJEEVANIreporter.nih.gov
Behavioral Economics and Population-based Colorectal Cancer ScreeningNIHNational Cancer Institute2021 to 2022$506,972September 15, 2018August 31, 2023MEHTA, SHIVAN JATINreporter.nih.gov
Improved Treatment of Colorectal Cancer with CF10 Diversity SupplementNIHNational Cancer Institute2021 to 2022$500,917February 1, 2022July 31, 2022GMEINER, WILLIAM H.reporter.nih.gov
How beta-catenin expands Foxp3+RORgammat+ Pro-inflammatory T-regulatory cellsNIHNational Institute of Allergy and Infectious Diseases2021$498,990April 20, 2015June 30, 2022GOUNARI, FOTINIreporter.nih.gov
Characterization of microbial and host requirements for colonic biofilm assembly and biofilm-mediated colon tumorigenesisNIHNational Cancer Institute2021 to 2022$497,999September 1, 2020August 30, 2024DREWES, JULIA Lreporter.nih.gov
Mechanisms of gut epithelial DUOX-mediated intestinal homeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$497,721April 1, 2018January 31, 2023KAO, JOHN Yreporter.nih.gov
(PQ6) Radiogenomics of colorectal polyps to assess benign proliferative vs. premalignant states.NIHNational Cancer Institute2021$491,493September 21, 2017March 31, 2022GRADY, WILLIAM MALLORYreporter.nih.gov
Effectiveness of screening for colorectal cancer in average risk adults: Colonoscopy vs FITNIHNational Cancer Institute2021$490,729April 10, 2017June 30, 2022DOUBENI, CHYKE ABADAMAreporter.nih.gov
Multidisciplinary Study of Folate Intake and Colorectal CancerNIHNational Cancer Institute2021 to 2022$481,357August 10, 2021February 29, 2024ZHANG, XUEHONGreporter.nih.gov
The role of PGC1beta and ERRalpha as novel targets for therapy in colorectal cancerNIHNational Cancer Institute2021 to 2022$475,164July 2, 2018June 30, 2023FISHER, KURTreporter.nih.gov
Development of nanoparticulate solution for cancer treatment by breakup of tumor extracellular hydroxyapatite: a new paradigmNIHNational Cancer Institute2021$472,960May 1, 2021April 30, 2024TANTAWY, MOHAMMED NOORreporter.nih.gov
Role of necroptosis in colorectal cancer therapyNIHNational Cancer Institute2023$461,812June 1, 2023May 31, 2025ZHANG, LINreporter.nih.gov
Ultra-bright fluorescent nanoparticles for colorectal adenoma detectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$461,090July 27, 2021May 31, 2024ROPER, JATINreporter.nih.gov
Targeting DNA Mismatches for Auger Electron RadiotherapyNIHNational Cancer Institute2023$457,607September 8, 2023August 31, 2025ZEGLIS, BRIAN MATTHEWreporter.nih.gov
Development of Drug Detoxifying Bacteria for Chemotherapy Induced Gut InjuryNIHNational Cancer Institute2021 to 2022$454,955September 23, 2021August 31, 2022SINGH, RASHIMreporter.nih.gov
A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral NeuropathyNIHNational Cancer Institute2022$452,540September 23, 2022August 31, 2025LEE, RICHARD Treporter.nih.gov
The role of the senescent microenvironment on cancer initiating cells in the colon.NIHNational Institute on Aging2021$451,960September 30, 2021March 31, 2022GRADY, WILLIAM MALLORYreporter.nih.gov
Neoadjuvant PD-1 blockade in mismatch repair deficient rectal cancerNIHNational Cancer Institute2021 to 2022$450,975February 1, 2021January 31, 2024CERCEK, ANDREAreporter.nih.gov
Patient-derived organoids reveal rectal cancers develop radiosensitivityNIHNational Cancer Institute2021 to 2022$450,147February 5, 2021January 31, 2024KOLESNICK, RICHARD Nreporter.nih.gov
CDHR5 tumor suppressor function in the intestineNIHNational Cancer Institute2021$449,218September 1, 2021August 31, 2025CRAWLEY, WILLIAM SCOTTreporter.nih.gov
Gut Microbiome, Antibiotic Use & Colon Cancer RecurrenceNIHNational Cancer Institute2021$446,142September 25, 2017August 31, 2025FEDIRKO, VERONIKAreporter.nih.gov
Virulence determinants of Fusobacterium nucleatumNIHNational Institute of Dental & Craniofacial Research2021$443,892September 1, 2018August 31, 2023TON-THAT, HUNGreporter.nih.gov
Strategy for Safe Colon-targeted Local Therapy of Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$441,111September 22, 2021June 30, 2025TUMMALA, HEMACHANDreporter.nih.gov
Gut microbiota-derived signaling in liver carcinogenesis and cancer treatmentNIHNational Cancer Institute2021 to 2023$440,819September 19, 2019August 31, 2024HU, YINGreporter.nih.gov
Designer EcN for treatment of solid tumorsNIHNational Cancer Institute2022 to 2023$440,436March 1, 2022February 28, 2025LESSER, CAMMIEreporter.nih.gov
Development of PDE5 Inhibitors for Localized Delivery to Prevent Colorectal CancerNIHNational Cancer Institute2021$439,332August 1, 2021January 31, 2025MIAO, SHAOBINreporter.nih.gov
Visualization and Epigenomic Characterization of Early Intestinal Tumorigenesis in MiceNIHNational Cancer Institute2021$434,625January 5, 2017December 31, 2021LAIRD, PETER Wreporter.nih.gov
Estrogenic protection against colorectal cancer development in obesityNIHNational Cancer Institute2023$433,500July 19, 2023June 30, 2026SHI, HAIFEIreporter.nih.gov
(PQ1) Mechanisms for Early Onset Colorectal CancerNIHNational Cancer Institute2021 to 2022$430,036August 1, 2021July 31, 2024ROSENBERG, DANIEL WILLIAMreporter.nih.gov
Defining the role of S1p and myeloid cells during enterotoxigenic B. fragilis infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$429,750September 22, 2021August 31, 2024DENG, ZHONG-BINreporter.nih.gov
Targeting the kinome in K-ras driven colorectal cancersNIHNational Cancer Institute2021$427,763December 8, 2016November 30, 2022DUNCAN, JAMES STUARTreporter.nih.gov
In vivo CRISPR-screening of novel cancer cell-intrinsic targets that sensitize to local ionizing radiation, and possible combination with systemic checkpoint blockade.NIHNational Cancer Institute2022 to 2023$425,653August 16, 2022July 31, 2025WEICHSELBAUM, RALPH Rreporter.nih.gov
Altered Lipid Metabolism as a Novel Target for Colon Cancer TreatmentNIHNational Cancer Institute2021$425,312August 1, 2017July 31, 2023EVERS, BERNARD MARKreporter.nih.gov
A novel Drosophila platform for sequential genetic manipulations in vivoNIHNational Institute of General Medical Sciences2021 to 2022$423,500July 1, 2021June 30, 2024BASS, HENRY Wreporter.nih.gov
Paracrine Role of Endothelial Cells in HER3-Mediated Colon Cancer Cell SurvivalNIHNational Cancer Institute2021 to 2022$420,869May 1, 2020April 30, 2024WANG, RUIreporter.nih.gov
Implementing and Evaluating Genetic Screening in Healthy Adults for Precision Public HealthNIHNational Human Genome Research Institute2022$420,769September 1, 2022August 31, 2024ROBERTS, MEGAN C.reporter.nih.gov
Breast, Colorectal, and Ovary Cancer Clinical Validation CenterNIHNational Cancer Institute2021$418,953August 16, 2010March 31, 2022LI, CHRISTOPHER Ireporter.nih.gov
Interrupting tumor progression by restoration of VDR expressionNIHNational Cancer Institute2022 to 2023$417,085April 1, 2022March 31, 2025NAKANISHI, MASAKOreporter.nih.gov
Biomarkers for Early Detection of Colorectal Cancer in Ulcerative ColitisNIHNational Cancer Institute2021 to 2022$415,805June 19, 2017May 31, 2024CHEN, RUreporter.nih.gov
Racial Disparities and Colorectal DNA Methylation- Driven Gene ExpressionNIHNational Cancer Institute2023$415,257September 15, 2023August 31, 2025LI, LIreporter.nih.gov
Hes1-loss promotes dysregulation of epithelial homeostasis and inflammation in a serrated adenocarcinoma modelNIHNational Cancer Institute2021 to 2022$415,164July 1, 2018March 31, 2023ZHOU, LANreporter.nih.gov
Modulation of microbiome function by host-derived noncoding small RNANIHNational Institute of Allergy and Infectious Diseases2021 to 2022$414,965June 1, 2021November 30, 2023JOBIN, CHRISTIANreporter.nih.gov
Development of a novel imaging modality for adoptive cell therapyNIHNational Cancer Institute2021$413,974September 17, 2021August 31, 2023WALD, DAVIDreporter.nih.gov
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults with Colorectal Cancer: The M&M StudyNIHNational Cancer Institute2021 to 2022$412,901September 1, 2018July 15, 2023WILLIAMS, GRANT Rreporter.nih.gov
Engaging diverse colorectal cancer survivors in the design of an adaptive text message-based intervention to improve diet qualityNIHNational Cancer Institute2022 to 2023$410,906August 1, 2022June 30, 2024VAN BLARIGAN, ERIN LYNNreporter.nih.gov
Understanding and Targeting Tiam1 in CancerNIHNational Cancer Institute2021 to 2022$410,209January 1, 2021December 31, 2023MANOR, DANNYreporter.nih.gov
Super Natural Killer Cells That Target Metastases in the Tumor-Draining Lymph NodesNIHNational Cancer Institute2021$409,817December 23, 2016November 30, 2022KING, MICHAEL R.reporter.nih.gov
Inhibition of CaMKK2 sensitizes rectal cancers to radiation therapyNIHNational Cancer Institute2021 to 2022$409,455January 1, 2021December 31, 2022ROPER, JATINreporter.nih.gov
Microfluidic Droplet Organoids to Decipher the Tumor Heterogeneity in CRC of African AncestryNIHNational Cancer Institute2022 to 2023$409,455March 1, 2022February 28, 2025HSU, SHIAOWEN DAVIDreporter.nih.gov
Cancer-specific metabolites as cues to engineer and target anti-tumor therapeutic bacteriaNIHNational Cancer Institute2022 to 2023$409,455August 1, 2022July 31, 2025DWIDAR, MOHAMMEDreporter.nih.gov
Integration of Genomic and Clinical Data to Enhance Subtyping of Colon CancerNIHNational Cancer Institute2021$407,754January 18, 2017June 30, 2022SINICROPE, FRANK A.reporter.nih.gov
Biomarkers for Reducing Mortality of Cancers of the Colon and EsophagusNIHNational Cancer Institute2021$407,598August 25, 2010September 30, 2022MARKOWITZ, SANFORD D.reporter.nih.gov
Epigenomic analysis of cell-free nucleosomes for cancer researchNIHNational Cancer Institute2023$406,374July 1, 2023June 30, 2024VENTERS, BRYAN Jreporter.nih.gov
Role of genetic and epigenetic alterations in CFTR in colorectal cancerNIHNational Cancer Institute2021 to 2022$405,711July 26, 2021June 30, 2024PRIZMENT, ANNAreporter.nih.gov
PG545 synergizes with PARP inhibitors in ovarian cancer to disrupt DNA repair through modulation of DEK-RAD51 axisNIHNational Cancer Institute2022 to 2023$404,369February 1, 2022January 31, 2025SHRIDHAR, VIJIreporter.nih.gov
Application of mucus modulating multipurpose trypsin nanoparticles to overcome the mucus barrier and deliver mitochondria-targeted anticancer drugs in mucinous carcinoma peritoneiNIHNational Cancer Institute2022 to 2023$404,369September 1, 2022August 31, 2025CHOUDRY, MOHAMMAD HAROON ASIFreporter.nih.gov
Are racial disparities in colon cancer due to epigenetic outliers.NIHNational Cancer Institute2021 to 2022$403,839July 16, 2021June 30, 2024SAPIENZA, CARMENreporter.nih.gov
Clinical biomarker for early prediction of chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2023$403,240September 19, 2023August 31, 2025HAROUTOUNIAN, SIMONreporter.nih.gov
CDK4/6 inhibition: a novel therapeutic strategy for GNAS-mutant gastrointestinal malignanciesNIHNational Cancer Institute2022 to 2023$401,826August 2, 2022June 30, 2025LOWY, ANDREW Mreporter.nih.gov
Cancer therapy with a combination of oncolytic bacteria and virus to enhance targeted cell killing and anti-tumor immune responsesNIHNational Cancer Institute2021 to 2022$400,018December 15, 2020November 30, 2023KONG, WEIreporter.nih.gov
Efficacy of an Electrophile Scavenger in the Prevention of Gastrointestinal Inflammatory CarcinogenesisNIHNational Cancer Institute2021$400,000April 9, 2021September 30, 2023RATHMACHER, JOHN Areporter.nih.gov
TOPIC 418 "HIGH THROUGHPUT SPATIALOMICS PROFILING FOR THICK TUMORTISSUES"NIHNational Cancer Institute2021$400,000September 16, 2021June 15, 2022HAUSER, ALANreporter.nih.gov
Exonuclease Based Microsatellite SequencingNIHNational Cancer Institute2022$400,000April 12, 2022March 31, 2024ERVIN, ERICreporter.nih.gov
Development of drug conjugates of R-spondin peptibodies for the treatment of colorectal cancerNIHNational Cancer Institute2023$400,000May 1, 2023April 30, 2025CUI, JIEreporter.nih.gov
Microsatellite Instability Sequencing via Single-Molecule DNA Re-ReadingNIHNational Cancer Institute2023$400,000September 18, 2023March 31, 2025SCHIBEL, ANNAreporter.nih.gov
SBIR Topic #446 Phase I -Development of Senotherapeutic Agents for Cancer TreatmentNIHNational Cancer Institute2023$400,000September 25, 2023September 24, 2024FROST, GRANT Breporter.nih.gov
SBIR PHASE I TOPIC 431, INTEGRATED CELL CULTURE CHAMBER AND FLOW GUIDE FOR POC, WALK-AWAY OPERATION FOR AUTOLOGOUS T CELL MANUFACTURINGNIHNational Cancer Institute2022$398,625September 15, 2022September 14, 2023MONTY, NATHANreporter.nih.gov
Preclinical Evaluation of a Novel ADAM10 Modulator to Treat ColorectalCancerNIHNational Cancer Institute2023$397,916May 10, 2023April 30, 2024PREMSRIRUT, PREM KHOVABUTRreporter.nih.gov
Development of Novel Combination Strategies to Overcome Resistance to KRASG12C Inhibition in Colorectal CancersNIHNational Cancer Institute2022 to 2023$397,469August 1, 2022July 31, 2025LEOPOLD, JUDITH Sreporter.nih.gov
Microbiome-derived regulators of therapy-resistant colorectal tumorsNIHNational Cancer Institute2022 to 2023$397,033August 9, 2022July 31, 2025GRIFFIN, TIMOTHY J.reporter.nih.gov
Novel Antibody-Drug Conjugate Combination Therapy for Treating Colorectal CancerNIHNational Cancer Institute2022 to 2023$396,739February 1, 2022January 31, 2025CARMON, KENDRA S.reporter.nih.gov
Organoid modeling of pre-metastatic niche formation in the liver by primary colorectal tumor secreted factorsNIHNational Cancer Institute2022 to 2023$395,529August 23, 2022January 31, 2025SKARDAL, ALEKSANDERreporter.nih.gov
Cancer Hijacks Enzyme Substrate Mutations to Facilitate TumorigenesisNIHNational Cancer Institute2022 to 2023$395,468May 1, 2022April 30, 2025LIU, PENGDAreporter.nih.gov
L1 element mutagenesis as a driver of epithelial cancers in African AmericansNIHNational Cancer Institute2022 to 2023$393,647January 1, 2022December 31, 2024DEVINE, SCOTT Ereporter.nih.gov
Biodegradable nanocarriers and antibodies as targeting delivery vehicles for cancer metallodrugsNIHNational Institute of General Medical Sciences2021$392,500June 1, 2018July 31, 2023CONTEL, MARIAreporter.nih.gov
Colorectal screening fear-reduction and racially-targeted norm messaging entreaties to increase colorectal cancer screening rates among African AmericansNIHNational Institute on Minority Health and Health Disparities2021 to 2023$392,495September 25, 2021June 30, 2025MANNING, MARK Areporter.nih.gov
Understanding the full spectrum of epigenetic vulnerability in cancer through the delineation of DNA methylation function in gene 3' endNIHNational Cancer Institute2023$392,412January 19, 2023March 31, 2025TING, ANGELA Hreporter.nih.gov
Exploration of Novel Mutation Biomarkers to Repurpose EGFRi for Mutant KRAS Colorectal CancerNIHNational Cancer Institute2021 to 2022$392,146July 15, 2021June 30, 2025FLOROU, VAIAreporter.nih.gov
Optimizing the Population Representativeness of Older Adults in Cancer TrialsNIHNational Cancer Institute2021$392,116April 8, 2021March 31, 2024BIAN, JIANGreporter.nih.gov
ctDNA for the Early Detection and Monitoring of Colorectal CancerNIHNational Cancer Institute2021$390,867September 7, 2010March 31, 2022SCHOEN, ROBERT E.reporter.nih.gov
A HTS Approach to Discover Guanine Nucleotide-Competitive Inhibitors of Oncogenic KRASNIHNational Cancer Institute2021$389,545September 13, 2018August 31, 2023ROSSMAN, KENTreporter.nih.gov
Chronic Kidney Disease Development in Cancer Treatment and SurvivalNIHNational Cancer Institute2021$389,545September 16, 2021December 31, 2023HILL, DEIRDREreporter.nih.gov
Engineered Enteric Nervous System-Peri Neural Invasion platform to improve predictive preclinical screens in early-stage colorectal adenocarcinomasNIHNational Cancer Institute2021 to 2022$388,972July 1, 2021June 30, 2024RAGHAVAN, SHREYAreporter.nih.gov
Validating p53 Ser46 crotonylation as a potential target for possible anti-cancer therapyNIHNational Cancer Institute2022 to 2023$387,941July 26, 2022June 30, 2025LU, HUAreporter.nih.gov
Bacteriophage-mediated microbiota modification to prevent colorectal cancer developmentNIHNational Cancer Institute2022 to 2023$387,838May 10, 2022February 28, 2025EL HADDAD, LYNNreporter.nih.gov
Mechanisms of cell death and autophagy in intestinal epithelial cells in inflammation and cancerNIHNational Cancer Institute2021$387,731March 21, 2017February 28, 2022MOSCAT, JORGEreporter.nih.gov
A large animal model to elucidate the role of LGR5 stem cells in cancerNIHNational Cancer Institute2021 to 2022$387,278February 1, 2021January 31, 2024PIEDRAHITA, JORGE Areporter.nih.gov
Development of Superior Chelation Chemistry for 89Zr-ImmunoPET ImagingNIHNational Institute of Biomedical Imaging and Bioengineering2021$386,534September 15, 2020July 31, 2022CHONG, HYUN-SOONreporter.nih.gov
Pragmatic randomized trial of polygenic risk scoring for common diseases in primary careNIHNational Human Genome Research Institute2021$386,100September 1, 2019June 30, 2022VASSY, JASON Lreporter.nih.gov
Suppression of Dominant-Negative Transcripts Escaping from Nonsense-Mediated mRNA DecayNIHNational Institute of General Medical Sciences2022 to 2023$383,110September 20, 2022August 31, 2024KUROSAKI, TATSUAKIreporter.nih.gov
Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal CancerNIHNational Cancer Institute2021$383,077September 1, 2019August 31, 2023DE VLAMINCK, IWIJNreporter.nih.gov
Cell type and molecular determinants of colorectal cancer initiation downstream of APC inactivationNIHNational Cancer Institute2021$382,375June 1, 2017May 31, 2023LENGNER, CHRISTOPHER JOACHIMreporter.nih.gov
MicroRNA regulation of endothelial DNA repair to enhance anti-tumor immunityNIHNational Heart, Lung, and Blood Institute2021$382,183July 20, 2018April 30, 2023ANAND, SUDARSHANreporter.nih.gov
Anticancer Effects of a Repurposed Drug in Colon CancerNIHNational Cancer Institute2023$381,834September 1, 2023August 31, 2025DATTA, PRAN Kreporter.nih.gov
Development of a patient-derived organotypic spheroids (PDOTS) platform for prediction of clinical responses to immuno-oncology drugsNIHNational Cancer Institute2021$381,800September 1, 2021August 31, 2022AREF, AMIR REZAreporter.nih.gov
Spectral precision imaging for early diagnosis of colorectal lesions with CT colonographyNIHNational Cancer Institute2021 to 2022$380,147December 1, 2017November 30, 2024YOSHIDA, HIROYUKIreporter.nih.gov
CRL3KEAP1 complex licenses genotoxic stress-induced tumor cell deathNIHNational Cancer Institute2021 to 2022$380,098April 1, 2021March 31, 2023GONG, YI-NANreporter.nih.gov
Understanding the regulatory role and therapeutic potential of long non-coding RNAs in metastatic colorectal cancerNIHNational Cancer Institute2021 to 2022$378,924July 1, 2020June 30, 2024SILVA-FISHER, JESSICAreporter.nih.gov
Ex Vivo Profiling of Immunotherapy Combinations Using Organotypic Tumor SpheroidsNIHNational Cancer Institute2021 to 2022$378,260August 16, 2018July 31, 2023JENKINS, RUSSELL WILLIAMreporter.nih.gov
Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon CarcinogenesisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$378,000June 10, 2018May 31, 2023BISHEHSARI, FARAZreporter.nih.gov
Deciphering the Code for Senescence Escape During Cancer Progression in HumansNIHNational Cancer Institute2021$376,527August 9, 2010January 31, 2024HERBIG, UTZreporter.nih.gov
Novel effects of xenoestrogens and gut microbiota derived estrogenic compounds in colonic inflammationNIHNational Institute of Environmental Health Sciences2022$374,998September 6, 2022May 31, 2024JAYARAMAN, ARULreporter.nih.gov
The role of butyrate-producing bacteria in CIMP colorectal cancer tumorigenesisNIHNational Cancer Institute2021$373,477March 15, 2017February 28, 2022WILLIAMS, BRENT LAMONTreporter.nih.gov
Signature-guided therapy for mismatch repair defective cancersNIHNational Cancer Institute2021$373,331August 1, 2017July 31, 2023LIN, SHIAW-YIHreporter.nih.gov
The role of leukemia inhibitory factor in colorectal cancerNIHNational Cancer Institute2022$372,497February 1, 2022January 31, 2023HU, WENWEIreporter.nih.gov
The LIN28b-Let7-IMP1 axis in colonic epithelial biologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$371,155March 1, 2000May 31, 2022RUSTGI, ANIL Kreporter.nih.gov
Stimulating Lymphocyte Activation Combined with Inhibition of Immunosuppressive Signals in Colon Cancer MetastasesNIHNational Cancer Institute2021$365,771January 22, 2020December 31, 2024MAKER, AJAY V.reporter.nih.gov
Utility of Random Biopsies in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$365,625September 21, 2022August 31, 2024LEWIS, JAMES Dreporter.nih.gov
Selenium Chemoprevention: Benefits and HarmsNIHNational Cancer Institute2021$364,547July 1, 2011May 31, 2022JACOBS, ELIZABETH Treporter.nih.gov
SENP6, a novel p53 negative regulator, is an important new player in cancerNIHNational Cancer Institute2021$363,713July 1, 2018June 30, 2022FENG, ZHAOHUIreporter.nih.gov
Endogenous and Dietary Sphingolipids as Modulators in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$363,375June 15, 2018May 31, 2023SABA, JULIE Dreporter.nih.gov
Beyond Body Mass Index: Bringing Body Composition into Oncology PracticeNIHNational Cancer Institute2021 to 2022$358,714April 1, 2018March 31, 2023FELICIANO, ELIZABETH MARJORIE CESPEDESreporter.nih.gov
Guanylin GUCY2C axis in Colorectal Cancer InitiationNIHNational Cancer Institute2021$357,970January 1, 2017December 31, 2022WALDMAN, SCOTT Areporter.nih.gov
Targeting TGFbeta/PDK4 to Overcome Drug Resistance in Colorectal CancerNIHNational Cancer Institute2021$356,850August 16, 2018August 31, 2022WANG, JINGreporter.nih.gov
SENP6, a novel p53 negative regulator, is an important new player in cancerNIHNational Cancer Institute2022$356,438July 1, 2018June 30, 2024FENG, ZHAOHUIreporter.nih.gov
Network-Based Novel Therapeutics in Colorectal CancersNIHNational Center for Advancing Translational Sciences2022$355,500September 11, 2019July 31, 2023GHOSH, PRADIPTAreporter.nih.gov
Precision therapeutics of inflammatory bowel disease guided by Boolean logicNIHNational Center for Advancing Translational Sciences2023$355,500August 28, 2020July 31, 2024SAHOO, DEBASHISreporter.nih.gov
G-CSF inhibition as a colorectal cancer therapyNIHNational Cancer Institute2021$355,323July 6, 2016June 30, 2023BESWICK, ELLEN J.reporter.nih.gov
A Novel Device Alternative to Temporary Diverting Ostomies after Rectal Cancer SurgeryNIHNational Cancer Institute2021 to 2022$353,509June 22, 2022January 31, 2023FONG, KENTON DODYANreporter.nih.gov
Site-specific epigenetic activation of TP53 to improve cancer therapyNIHNational Institute of General Medical Sciences2021$350,000September 16, 2021September 15, 2023HATHAWAY, NATHANIEL A.reporter.nih.gov
Surgery triggered immune response and liver metastasesNIHNational Cancer Institute2021 to 2022$348,373January 1, 2018June 26, 2022TSUNG, ALLANreporter.nih.gov
DNA damage signaling to immune checkpointsNIHNational Cancer Institute2021$347,953January 1, 2017December 31, 2022BAKKENIST, CHRISTOPHER J.reporter.nih.gov
Role of HOS in Cell Transformation and ApoptosisNIHNational Cancer Institute2021$344,138March 1, 2001November 30, 2021FUCHS, SERGE Yreporter.nih.gov
Functional characterization of novel oncogenic loci driving progression and immune response in gastrointestinal cancerNIHNational Cancer Institute2021 to 2022$343,440September 1, 2021February 28, 2023LO, YUAN-HUNGreporter.nih.gov
The role of Dclk1 in the initiation of colorectal cancerNIHNational Cancer Institute2021$338,550June 15, 2017May 31, 2023HOUCHEN, COURTNEY WAYNEreporter.nih.gov
A phase-1 trial of intraperitoneal 5-fluorouracil and oxaliplatin in patients with colorectal cancer and unresectable peritoneal metastasis.NIHNational Cancer Institute2023$336,425September 12, 2023August 31, 2025MITTRA, ARJUNreporter.nih.gov
Mechanism of colon cancer metastasis: combined role of activin and TGF-beta signalingNIHNational Cancer Institute2021$332,601September 27, 2010March 31, 2023JUNG, BARBARA Hreporter.nih.gov
Increasing Colorectal Cancer Screening in Alaska Native MenNIHNational Institute of Nursing Research2021 to 2022$331,502June 18, 2021June 30, 2024MULLER, CLEMMA JACOBSENreporter.nih.gov
Implementation and Impact of Cancer Screening Navigation by Community Health Workers in Two National Screening ProgramsNIHNational Cancer Institute2021 to 2022$329,385September 15, 2018August 31, 2024BARRINGTON, WENDY ELIZABETHreporter.nih.gov
Uncovering the Role of Colorectal Stem Cells on Disease Penetrance in Lynch SyndromeNIHNational Cancer Institute2021$320,000September 12, 2017August 31, 2023VILAR SANCHEZ, EDUARDOreporter.nih.gov
Identification of Microbiome Based Markers to Improve Colorectal Cancer DetectionNIHNational Cancer Institute2021$319,318January 15, 2018December 31, 2021SCHLOSS, PATRICK DAVIDreporter.nih.gov
Diabetes, Medications and the Cost-Effectiveness of Screening for Colorectal NeoplasiaNIHNational Cancer Institute2021 to 2022$316,306September 1, 2018August 31, 2024HARDIKAR, SHEETALreporter.nih.gov
Network-Based Novel Therapeutics in Colorectal CancersNIHNational Center for Advancing Translational Sciences2021$316,000September 11, 2019July 31, 2022GHOSH, PRADIPTAreporter.nih.gov
Detection of microsatellite instability biomarkers for therapeutic clinical trial eligibilityNIHNational Cancer Institute2021$314,062September 25, 2017March 31, 2022ROYCHOWDHURY, SAMEEKreporter.nih.gov
Optimizing Colorectal Cancer Screening among Patients with Diabetes in Safety-Net Primary Care Settings: Targeting Implementation ApproachesNIHNational Cancer Institute2021 to 2022$313,199January 1, 2021May 31, 2022O'MALLEY, DENALEE M.reporter.nih.gov
Coordinate roles of histone H3K27me3 and DNA methylation in intestinal homeostasis and tumorigenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$310,608January 1, 2018November 30, 2022JADHAV, UNMESHreporter.nih.gov
Novel Molecular Biomarkers and Therapeutics for Colorectal CancerNIHNational Cancer Institute2021 to 2022$310,128September 18, 2018August 31, 2023FINK, STEPHEN PAULreporter.nih.gov
CLINCIAL VALIDATION OF APC AND TP53 AS BIOMARKERS FOR CETUXIMAB RESPONSENIHNational Cancer Institute2023$309,375April 1, 2023March 31, 2025YEATMAN, TIMOTHY Jreporter.nih.gov
Improving Routine Asymptomatic Cancer Screening among Federally Qualified Health Center Users in Florida: Application of a Health Literacy FrameworkNIHNational Cancer Institute2021 to 2022$309,240April 1, 2018March 31, 2023BEST, ALICIA LYNETTEreporter.nih.gov
NCI PATTERNS OF CARE STUDY - DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCERNIHNational Cancer Institute2023$303,638December 23, 2022December 22, 2023SHRESTHA, ANSHUreporter.nih.gov
Use of a Novel Toilet Seat to Passively Collect Digital Biomarkers in Assisted Living SettingsNIHNational Institute on Aging2021$299,676September 1, 2021August 31, 2024BAYAT SARMADI, PARMOONreporter.nih.gov
A microscope for ultra-high multiplex spatial imaging of transcripts and proteins in tissuesNIHOffice of the Director, National Institutes of Health2023$299,500April 1, 2023March 31, 2024HACOHEN, NIRreporter.nih.gov
A novel thermogel for topical treatment of ulcerative colitis with microbialmetabolite mimicry.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023$296,475June 1, 2023May 31, 2025LINHARDT, JEFFREYreporter.nih.gov
Spatial Molecular Imager for Translational ResearchNIHOffice of the Director, National Institutes of Health2023$295,000May 15, 2023May 14, 2024FRAIETTA, JOSEPH ANTHONYreporter.nih.gov
I-SCREEN: Increasing Screening for Cancer using a Randomized Evaluation of EHR-based NudgesNIHNational Institute on Aging2021$294,241August 15, 2020July 31, 2022NAVATHE, AMOL Sreporter.nih.gov
Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and Liver Cancer (CLOVER)NIHNational Institute on Aging2021$293,756August 15, 2020July 31, 2022CHAK, ERIC Wreporter.nih.gov
Targeting regenerative reprogramming in colorectal cancerNIHNational Cancer Institute2023$292,597September 1, 2023June 30, 2024ALONSO MARTINEZ, SALVADORreporter.nih.gov
A Novel Bacterially-derived Product to Enhance Immunity and Response to Immune Checkpoint TherapyNIHNational Institute of Allergy and Infectious Diseases2022$289,194May 6, 2022April 30, 2024KOH, ANDREWreporter.nih.gov
Dietary Regulation of Colon Cancer MetastasisNIHNational Cancer Institute2021 to 2023$283,042May 1, 2021January 18, 2024GOSWAMI, SWAGATAreporter.nih.gov
Improving Cancer Screening Through A Tailored Technology-Based InterventionNIHNational Institute on Aging2021$283,016August 15, 2020July 31, 2022DIAZ, VANESSA ASTRUDreporter.nih.gov
Targeting casein kinase 1-alpha for cancer therapyNIHNational Cancer Institute2021 to 2022$282,603July 6, 2018June 30, 2024CORSELLO, STEVEN MUNTEANreporter.nih.gov
Investigation of the Carcinogenic Effects of Bactericidal Antibiotics in the GutNIHNational Cancer Institute2021 to 2023$278,201February 1, 2021March 14, 2023SHIN, WOOJUNGreporter.nih.gov
Nuclear Transport of Extracellular Vesicle BiomaterialsNIHNational Cancer Institute2021$275,000August 1, 2021July 31, 2024LORICO, AURELIOreporter.nih.gov
EPICERTIN for Mucosal Healing in Ulcerative ColitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$273,556September 19, 2022August 31, 2024TUSE, DANIELreporter.nih.gov
Improving the safety and effectiveness of adhesion prevention following colorectal procedures with high risk of cancer or infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$269,911September 30, 2022August 31, 2024KEANE, TIMOTHY JOSEPHreporter.nih.gov
SESORRS endoscopy for the staging and evaluation of colorectal cancerNIHNational Cancer Institute2022 to 2023$266,978June 8, 2022December 31, 2023NICOLSON, FAYreporter.nih.gov
The Effects of Insurance Benefit Design Innovation on Patient HealthNIHNational Institute on Aging2021 to 2023$259,455March 15, 2019August 15, 2023WHALEY, CHRISTOPHERreporter.nih.gov
Dye-free, multimodal, quantitative imaging to assess bowel perfusion during laparoscopic colorectal resectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$256,579September 1, 2021August 31, 2023CHA, RICHARD JAEPYEONGreporter.nih.gov
Low Cost Spectroscopic OCT for GI ApplicationsNIHNational Institute of Biomedical Imaging and Bioengineering2021$256,323September 20, 2021December 19, 2022BROWN, WILLIAMreporter.nih.gov
Molecular Mechanisms Underlying Environmental Effects that Influence Penetrance in Lynch Syndrome-Associated Endometrial CancerNIHNational Cancer Institute2021$256,000April 5, 2017February 28, 2024YATES, MELINDA S.reporter.nih.gov
Optimizing Thermal Ablation for Colon Cancer Liver Metastases: Rapid Tissue Analysis Allowing for Immediate Retreatment; Metabolic Imaging Biomarker Validation; and Predictive Genetic SignaturesNIHNational Cancer Institute2022$251,889September 12, 2019February 29, 2024SOFOCLEOUS, CONSTANTINOS THASOSreporter.nih.gov
Impact of sugary drinks on gut microbiota and development of young-onset colorectal cancerNIHNational Cancer Institute2021$251,400June 1, 2021August 31, 2022YUN, JIHYEreporter.nih.gov
Inflammation, Physical Activity, and Colon Cancer Recurrence and SurvivalNIHNational Cancer Institute2021$249,000April 3, 2019March 31, 2024BROWN, JUSTIN Creporter.nih.gov
The effects of Ojeok-san on neuro-immune interactions in cancer-induced visceral painNIHNational Center for Complementary & Integrative Health2021$249,000September 1, 2019August 31, 2023VELAZQUEZ, KANDY Treporter.nih.gov
Optimizing Colorectal Cancer Screening among Patients with Diabetes in Safety-Net Primary Care Settings: Targeting Implementation ApproachesNIHNational Cancer Institute2022$249,000January 1, 2021May 31, 2023O'MALLEY, DENALEE M.reporter.nih.gov
Early prediction of colorectal liver metastases treatment response with ultrasound microvessel imagingNIHNational Cancer Institute2021$248,964March 1, 2017January 31, 2023SONG, PENGFEIreporter.nih.gov
American Samoa Indigenous Samoan Partnership to Initiate REsearch Excellence (INSPIRE) in Colorectal Cancer Health LiteracyNIHNational Institute on Minority Health and Health Disparities2021$246,550July 1, 2016January 31, 2023TOFAEONO, VAATAUSILI Treporter.nih.gov
Inferring the roots of metastases and their effects on patient survivalNIHNational Cancer Institute2021$245,022July 1, 2018August 28, 2022REITER, JOHANNES Greporter.nih.gov
Dissecting roles of microbiome-host interactions in colorectal neoplasia etiology using multi-omics dataNIHNational Cancer Institute2021 to 2022$242,406January 5, 2021December 31, 2022YANG, YAOHUAreporter.nih.gov
Influence of Dietary Pattern and Race on Metabolic and Epigenetic Alterations Associated with Cancer DevelopmentNIHNational Institute on Minority Health and Health Disparities2021 to 2022$240,748September 25, 2020April 30, 2024MILES, FAYTHreporter.nih.gov
Overcoming barriers to cancer screening among women living in rural and segregated communitiesNIHNational Cancer Institute2021 to 2022$239,476September 1, 2019August 31, 2023MOSS, JENNIFER LINDSAYreporter.nih.gov
Defining host-microbiota interactions during colorectal cancer and immune checkpoint blockadeNIHNational Cancer Institute2021$237,724April 1, 2020March 31, 2023SONNENBERG, GREGORY Freporter.nih.gov
Targeting the IL-33/ST2 Pathway in Colorectal Cancer ImmunotherapyNIHNational Cancer Institute2021 to 2022$237,442April 1, 2021September 30, 2022VAN DER JEUGHT, KEVINreporter.nih.gov
Optimal early colorectal cancer screening initiationNIHNational Cancer Institute2022 to 2023$233,896September 1, 2022December 31, 2024DEMB, JOSHUA BRIANreporter.nih.gov
Tumor-specific activation of transgene expression by Scd3 locusNIHNational Cancer Institute2021$230,010December 11, 2019November 30, 2023NAKANISHI, MASAKOreporter.nih.gov
Reducing serine biosynthesis and utilization as a novel approach for colon cancer preventionNIHNational Cancer Institute2021$229,478February 1, 2019January 31, 2022MONTROSE, DAVID Creporter.nih.gov
Delineating the mechanisms by which tumor immunity multicellular networks shape T cell stateNIHNational Cancer Institute2023$226,554August 23, 2023June 30, 2024CHEN, JONATHAN HOWARDreporter.nih.gov
Statistical Methods for Analysis of Tumor Heterogeneity in Genetic EpidemiologyNIHNational Cancer Institute2021$218,775July 1, 2015March 31, 2022HSU, LIreporter.nih.gov
APC + TP53 Combinatorial Mutations Emerging as Biomarkers to Predict EGFRI SensitivityNIHNational Cancer Institute2021$213,881August 1, 2021April 16, 2022YEATMAN, TIMOTHY Jreporter.nih.gov
Leveraging Implementation Science to Promote Behavior Change and Reduce Cancer Health Disparities among American Indian and Alaska Native Older AdultsNIHNational Cancer Institute2021 to 2023$206,400May 4, 2021August 31, 2023PEDERSEN, MAJAreporter.nih.gov
Investigating cancer metabolism and its potential for therapeutic interventionNIHNational Cancer Institute2021 to 2022$204,317July 23, 2019December 23, 2022MONTAL, EMILY DINAreporter.nih.gov
The role of Fusobacterium in colorectal cancer treatment, tumor ecology and chemotherapeutic efficacyNIHNational Cancer Institute2021$204,273August 1, 2019March 31, 2022BULLMAN, SUSANreporter.nih.gov
A Metabolic Engineering Strategy to Map Sialyltransferase GlycositesNIHNational Institute of General Medical Sciences2021 to 2023$202,284July 26, 2021July 25, 2024TILL, NICHOLAS ALEXANDERreporter.nih.gov
Defining an immunological mechanism for a microbiota-based therapy for colorectal cancerNIHNational Cancer Institute2021$200,410March 6, 2020February 28, 2022HAND, TIMOTHY WESLEYreporter.nih.gov
Use of simulation-based mastery learning to improve polypectomy outcomesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$198,958June 1, 2020March 31, 2024BARSUK, JEFFREY Hreporter.nih.gov
Alcohol, Gut Dysbiosis, Endotoxemia, and Colorectal CancerNIHNational Institute on Alcohol Abuse and Alcoholism2021$195,270February 20, 2020January 31, 2023CAO, YINreporter.nih.gov
Defining the relationship between kinase inhibitor pharmacophores and pro-/anti-targets using in vivo models of colorectal cancerNIHNational Cancer Institute2021 to 2022$195,178February 15, 2019April 29, 2022MARSIGLIA, WILLIAM Mreporter.nih.gov
Targeting macrophages to reduce colorectal cancer: Impact of metabolic reprogrammingNIHNational Cancer Institute2021 to 2022$193,112September 14, 2018August 31, 2023BADER, JACKIEreporter.nih.gov
High-Throughput Functional Genomics to Guide Precision Oncology in Gastrointestinal TumorsNIHNational Cancer Institute2021$192,240January 1, 2019December 31, 2021SHEN, JOHN PAUL YING CHINGreporter.nih.gov
Colon cancer prevention with non-systemic PDE5 inhibitorsNIHNational Cancer Institute2022$191,738August 1, 2022July 31, 2024BROWNING, DARREN D.reporter.nih.gov
Saturation genome editing approach to functionally test all possible MSH2 variantsNIHNational Cancer Institute2021$191,675December 12, 2019November 30, 2023HEINEN, CHRISTOPHER D.reporter.nih.gov
Comprehensive identification of RAS mutations and allelic co-segregation patterns in colorectal cancerNIHNational Cancer Institute2021 to 2022$187,000December 14, 2020November 30, 2023SEREBRIISKII, ILYAreporter.nih.gov
Determinants of Repeat Colorectal Cancer Screening in a Safety-Net SystemNIHNational Cancer Institute2022 to 2023$180,582July 1, 2022June 30, 2025NONZEE, NARISSA JENNIFERreporter.nih.gov
The role of DCLK1 in the initiation of pancreatic ductal adenocarcinoma and colorectal cancerNIHNational Cancer Institute2021 to 2022$179,310September 19, 2018August 31, 2023QU, DONGFENGreporter.nih.gov
Developing a Barbershop-Based Trial on Masculinity Barriers to Care and Colorectal Cancer Screening Uptake among African-American Men using a Mixed Methods ApproachNIHNational Cancer Institute2021$175,673September 17, 2018May 20, 2022ROGERS, CHARLES R.reporter.nih.gov
Developing a Barbershop-Based Trial on Masculinity Barriers to Care and Colorectal Cancer Screening Uptake among African-American Men using a MixedMethods ApproachNIHNational Cancer Institute2022$175,673September 17, 2018August 31, 2024ROGERS, CHARLES R.reporter.nih.gov
NCI PATTERNS OF CARE STUDIES FOR DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCER CASESNIHNational Cancer Institute2023$173,602December 23, 2022December 22, 2023DURBIN, ERICreporter.nih.gov
Development of a noninvasive, rapid and affordable method for early detection of colorectal cancerNIHNational Cancer Institute2021 to 2022$172,029July 1, 2020June 30, 2025OSKERITZIAN, CAROLE Areporter.nih.gov
APC + TP53 Combinatorial Mutations Emerging as Biomarkers to Predict EGFRI SensitivityNIHNational Cancer Institute2022$171,233April 16, 2022July 31, 2024YEATMAN, TIMOTHY Jreporter.nih.gov
Targeting ERK5 for Colorectal Cancer TherapyNIHNational Cancer Institute2021$169,469May 13, 2020August 31, 2022POWIS, GARTHreporter.nih.gov
Cancer Emulation Analysis with Deep Neural NetworkNIHNational Cancer Institute2023$167,500September 19, 2023August 31, 2025MA, SHUANGGEreporter.nih.gov
Targeting Wnt-dependent colorectal cancerNIHNational Cancer Institute2021$166,963March 1, 2018May 31, 2021ROBBINS, DAVID Jreporter.nih.gov
Delineating the Role of KAP1 in WNT-induced Colorectal CancerNIHNational Cancer Institute2022 to 2023$164,000January 1, 2022December 31, 2023D'ORSO, IVANreporter.nih.gov
A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalkNIHNational Cancer Institute2021$162,759May 1, 2019August 31, 2022KIM, HYUN JUNGreporter.nih.gov
Measuring Gender in the Healthy Oregon ProjectNIHNational Cancer Institute2023$161,578September 13, 2023May 31, 2025SHANNON, JACKILENreporter.nih.gov
Gene Dependent Cancer Risk and Optimal Cancer Prevention Strategies in Lynch SyndromeNIHNational Cancer Institute2021$158,516April 11, 2018September 30, 2022SHARAF, RAVIreporter.nih.gov
Identifying the active factor of an anti-inflammatory chemopreventive bacteriumNIHNational Cancer Institute2021$157,235May 1, 2021February 5, 2022CROTT, JIMMY Wreporter.nih.gov
Role of a Two-Factor Genetic Circuit Regulating Stemness in Colorectal CancerNIHNational Cancer Institute2021 to 2023$155,482June 1, 2021October 31, 2025HU, SOFIAreporter.nih.gov
Infertility and Risk of Breast, Gynecologic, and Colorectal CancerNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$153,500April 1, 2021March 31, 2024FARLAND, LESLIE Vreporter.nih.gov
Fatty acid synthase in regulation of UDP-GlcNAc synthesis in colorectal cancerNIHNational Cancer Institute2021 to 2022$153,000July 1, 2021June 30, 2023ZAYTSEVA, YEKATERINAreporter.nih.gov
Alterations in DNA Damage following Major Surgery and Hyperthermic Intraperitoneal ChemotherapyNIHNational Cancer Institute2022 to 2023$152,670August 5, 2022July 31, 2024KIM, JOSEPHreporter.nih.gov
Colorectal tumorigenesis on a cricket powder-based diet versus diets based on more typical protein sourcesNIHNational Cancer Institute2021 to 2022$151,000March 8, 2021August 31, 2023MASON, JOEL Breporter.nih.gov
Global metabolomics profiling, dietary factors, and colorectal cancer risk in the NIH-Consortium of Metabolomics Studies (COMETS)NIHNational Cancer Institute2022 to 2023$150,975June 14, 2022May 31, 2025PLAYDON, MARY CHRISTINEreporter.nih.gov
Exploring the impact of HSP90 inhibition on antigen presentation and anti-tumor immune responsesNIHNational Cancer Institute2021$150,223March 2, 2020February 28, 2022JAEGER, ALEXreporter.nih.gov
Statistical methods for cancer progression delineation and subtype identificationNIHNational Cancer Institute2021 to 2022$149,804July 1, 2021June 30, 2024WANG, CHIreporter.nih.gov
Translational Epigenomics in Gastrointestinal CancerNIHNational Cancer Institute2021$147,343September 19, 2018March 31, 2022YU, MINGreporter.nih.gov
Malignant Cell Engagement in Immune Circuits of Human Microsatellite-stable and Microsatellite-instable Colorectal CancerNIHNational Cancer Institute2021$137,295April 8, 2021August 31, 2021PELKA, KARINreporter.nih.gov
The Functional Role of GRM3 in Colon CancerNIHNational Cancer Institute2021$135,998August 15, 2020June 21, 2022GENG, LIYINGreporter.nih.gov
AVGN7, a Novel Gene Therapeutic for Treating Cancer CachexiaNIHNational Cancer Institute2021$134,809September 25, 2017August 31, 2022RODGERS, BUELreporter.nih.gov
Developing an intervention to improve follow-up of abnormal fecal immunochemical test results in a safety-net population using a mixed methods approachNIHNational Cancer Institute2021$134,048September 1, 2019March 31, 2022ISSAKA, RACHEL B.reporter.nih.gov
Elucidating Molecular Mechanisms of Cancer Development by Investigating Key DNA Repair PathwaysNIHNational Cancer Institute2021$131,595September 1, 2020August 31, 2023LEBLANC, SHARONDAreporter.nih.gov
Targeting casein kinase 1-alpha for cancer therapyNIHNational Cancer Institute2021$130,475July 6, 2018February 28, 2022CORSELLO, STEVEN MUNTEANreporter.nih.gov
Investigating the Role of IL-23R in Mucosal Regulatory T CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$129,750July 10, 2020April 30, 2022GOETTEL, JEREMY ALLENreporter.nih.gov
Risk-stratified self-management care for colorectal cancer survivors: a new approach to increasing adherence to health behavior recommendationsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$129,507August 1, 2023July 31, 2024SLEIGHT, ALIX G.reporter.nih.gov
Shared decision-making and colorectal cancer screening behaviors among older adults with low health literacyNIHNational Institute on Aging2021$126,484January 15, 2020December 31, 2021CADET, TAMARA J.reporter.nih.gov
Investigating a Wnt-telomere feedback loop in the colorectal adenoma-carcinoma sequenceNIHNational Cancer Institute2021 to 2023$122,674March 1, 2021August 4, 2023ESTEP, KATRINA NOELreporter.nih.gov
Elucidating the Role of SMAD4 in Colorectal CancerNIHNational Cancer Institute2021$120,264May 1, 2020April 30, 2022TONG, KEVINreporter.nih.gov
An Engineered Nanocarrier Platform for Enhancing Immune Responses to Neoantigen-Targeted Cancer VaccinesNIHNational Cancer Institute2021 to 2023$119,772January 13, 2021May 13, 2023BALJON, JESSALYN Jreporter.nih.gov
Advanced genetic systems for Fusobacterium nucleatum in oral and extra-oral pathologiesNIHNational Institute of Dental & Craniofacial Research2023$119,645September 19, 2023May 1, 2024JOHNSTON, CHRISTOPHER Dreporter.nih.gov
Diet and the colonic exfoliome: a novel, non-invasive approach to testing interventions in humansNIHNational Cancer Institute2021$119,129January 1, 2020March 31, 2022LAMPE, JOHANNA Wreporter.nih.gov
Genetics of Tumor Suppression by p53NIHNational Cancer Institute2021$119,031March 4, 2020December 1, 2021BARNOUD, THIBAUTreporter.nih.gov
Deciphering the mechanism of colibactin-induced DNA damage through quantitative and biochemical approachesNIHNational Cancer Institute2021 to 2022$114,015July 6, 2020February 17, 2023CARLSON, ERIK Sreporter.nih.gov
The Social Environment and Colorectal Cancer in the United StatesNIHNational Cancer Institute2021 to 2023$112,964September 1, 2021June 30, 2024SANTIAGO-RODRIGUEZ, EDUARDO JOSEreporter.nih.gov
NCI PATTERNS OF CARE STUDY: (DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCER)NIHNational Cancer Institute2023$109,264December 23, 2022December 22, 2023SCHWARTZ, PHD, STEPHENreporter.nih.gov
Optimizing the Impact of Aspirin for ChemopreventionNIHNational Cancer Institute2021$108,708July 6, 2018September 30, 2022CAO, YINreporter.nih.gov
EFFECT OF WESTERN DIET IN GASTROINTESTINAL CANCER BY NMR METABOLOMICSNIHNational Institute of General Medical Sciences2021$105,000July 1, 2018June 30, 2024KRISHNAN, VISWANATHAN Vreporter.nih.gov
Adaptive immunity in primary sclerosing cholangitis patients at risk for colorectal cancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$102,788July 1, 2019June 30, 2023SHAW, DUSTINreporter.nih.gov
Developing multiplexed microenvironmental sensors for precision diagnostics of cancer metastasisNIHNational Cancer Institute2021$101,334December 1, 2019November 30, 2022HAO, LIANGLIANGreporter.nih.gov
Colonoscopy in young onset colorectal cancerNIHNational Cancer Institute2021 to 2022$101,291March 1, 2022August 31, 2022DEMB, JOSHUA BRIANreporter.nih.gov
Functional analyses of super-enhancer dysregulation in colorectal carcinoma patient samples.NIHNational Cancer Institute2021 to 2022$101,064July 1, 2019June 5, 2023ZHOU, ROYCEreporter.nih.gov
PATTERNS OF CARE STUDY: DIAGNOSIS YEAR 2020 (BREAST CANCER AND COLORECTAL CANCER)NIHNational Cancer Institute2023$97,457December 23, 2022December 22, 2023GONSALVES, LOUreporter.nih.gov
The Role of Klotho Beta in Colorectal Cancer TumorigenesisNIHNational Cancer Institute2021 to 2023$97,150January 4, 2021January 3, 2024ROHR, MICHAEL Wreporter.nih.gov
The role of unacylated ghrelin on age-associated progressive muscle weakness and cachexia elicited by cancerNIHNational Institute on Aging2021$95,979February 15, 2020January 31, 2022AHN, BUMSOOreporter.nih.gov
Restoring Guanylin-Guanylate cyclase C Signaling to Prevent Colorectal CancerNIHNational Cancer Institute2021 to 2022$95,324January 1, 2019December 31, 2022RAPPAPORT, JEFFREYreporter.nih.gov
Ferroptosis as a Modulator of Checkpoint Inhibitor ImmunotherapyNIHNational Cancer Institute2021 to 2023$94,531April 1, 2021March 31, 2024TALTY, RONAN CHRISTOPHERreporter.nih.gov
Molecular mechanisms of Trypanosoma cruzi induced colon pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$94,446December 9, 2021December 8, 2023RAYFORD, KAYLAreporter.nih.gov
Dissecting mechanisms of inflammation driven cancer susceptibility in epithelial barrier tissuesNIHNational Cancer Institute2021 to 2022$94,288September 1, 2021August 31, 2023COWLEY, CHRISTOPHERreporter.nih.gov
Bacterial Rogue Methyltransferases Inducing Human EpimutationsNIHNational Cancer Institute2021 to 2022$91,888June 1, 2021August 31, 2022FINK, EMILY Ereporter.nih.gov
PATTERNS OF CARE STUDY -DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCERNIHNational Cancer Institute2023$90,751December 23, 2022December 22, 2023MANISCALCO, LAURENreporter.nih.gov
Cell type and molecular determinants of colorectal cancer initiation downstream of APC inactivationNIHNational Cancer Institute2021$89,314September 19, 2017August 31, 2022LI, NINGreporter.nih.gov
NCI PATTERNS OF CARE STUDIES FOR DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCER CASESNIHNational Cancer Institute2023$88,805December 23, 2022December 22, 2023STROUP, ANTOINETTEreporter.nih.gov
Discovery and Mechanistic Characterization of New Cytotoxic Agents from Marine CyanobacteriaNIHNational Institute of General Medical Sciences2021 to 2022$88,646August 16, 2021August 15, 2023ELSADEK, LOBNAreporter.nih.gov
PATTERNS OF CARE (POC) STUDY: DIAGNOSIS YEAR 2020 (BREAST CANCER AND COLORECTAL CANCER)NIHNational Cancer Institute2023$87,431December 23, 2022December 22, 2023WIGGINS, CHARLESreporter.nih.gov
Elucidating the impact of DNA hypomethylation on genome organization and anti-tumor transcriptional programs.NIHNational Cancer Institute2021$87,051April 1, 2021August 31, 2021JOHNSTONE, SARAH Ereporter.nih.gov
Optimizing Gram-positive bacteria as a candidate for targeted anti-tumor therapyNIHNational Cancer Institute2021 to 2022$86,115July 1, 2020December 1, 2022SHUSTER, BENTLEY M.reporter.nih.gov
Function of IRF8 in T cell activation and immune toleranceNIHNational Cancer Institute2021 to 2022$84,901December 18, 2018May 13, 2022KLEMENT, JOHN DAVIDreporter.nih.gov
Functions of KAT2A and KAT2B in intestinal homeostasis and colon cancer.NIHNational Cancer Institute2021 to 2022$84,768September 1, 2020August 31, 2023NGUYEN, MAI UYENreporter.nih.gov
Exploring the Role of Drp1 in Colorectal CancerNIHNational Cancer Institute2021 to 2023$84,752April 1, 2021July 25, 2023HASANI, SUMATI RAJreporter.nih.gov
Investigating the role of EZH2 as a therapeutic target in colorectal cancersNIHNational Cancer Institute2021 to 2023$84,628April 1, 2021May 31, 2023LOI, PATRICKreporter.nih.gov
Biomarkers of Inflammation, Vitamin D, and Colorectal Cancer Risk and SurvivalNIHNational Cancer Institute2021 to 2022$84,329January 3, 2019June 28, 2022GIBBS, DAVID CORLEYreporter.nih.gov
Oncogenic Kras drives stromal adipogenesis to promote colorectal cancer (CRC) progressionNIHNational Cancer Institute2022 to 2023$83,670August 1, 2022November 8, 2023HSU, WEN-HAOreporter.nih.gov
Integrative Approach to Understand the Role of Diet, Physical Activity and Adiposity on Survival in Patients with Colorectal, Endometrial and Prostate CancerNIHNational Cancer Institute2021$82,818May 15, 2020April 30, 2022LEE, DONGHOONreporter.nih.gov
Missorting of EGFR in cancer pathogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$81,875March 10, 2020February 28, 2022SINGLA, AMIKAreporter.nih.gov
Sensitizing Colorectal Cancer to Checkpoint Inhibitors by WNT Pathway SuppressionNIHNational Cancer Institute2021 to 2022$81,540January 1, 2020August 2, 2022KATTI, ALYNAreporter.nih.gov
Engineering injectable T cell stimulating microparticles for cancer immunotherapyNIHNational Cancer Institute2022 to 2023$81,027September 1, 2022March 8, 2024LIVINGSTON, NATALIE KATERINAreporter.nih.gov
Epigenetic regulation of myeloid regulatory cell accumulation in the tumor microenvironmentNIHNational Cancer Institute2021 to 2022$80,603December 18, 2020June 30, 2022MERTING, ALYSSAreporter.nih.gov
Defining the function of SETD8 in colorectal cancerNIHNational Cancer Institute2021 to 2022$80,215March 1, 2020February 28, 2023CRAMER, ZVIreporter.nih.gov
ω-3 fatty acid-derived mediators promote resolution of inflammation: Uncovering new strategies for preventing colitis-associated colon cancerNIHNational Cancer Institute2021$80,000February 10, 2020January 31, 2023ZUO, XIANGSHENGreporter.nih.gov
WDR5 WIN Site Inhibition in Colorectal CancerNIHNational Cancer Institute2022$79,988July 1, 2022June 30, 2023GRIEB, BRIAN Creporter.nih.gov
NCI PATTERNS OF CARE STUDY: DIAGNOSIS YEAR (2020 BREAST CANCER AND COLORECTAL CANCER)NIHNational Cancer Institute2023$79,740December 23, 2022December 22, 2023DOHERTY, JENNIFERreporter.nih.gov
Characterization of the PKM2-RAS Interaction as a Novel Metabolic Vulnerability of RAS-driven TumorsNIHNational Cancer Institute2021 to 2022$76,330April 1, 2021March 31, 2023KOCHEN ROSSI, JUAN ANDRESreporter.nih.gov
Identification of a central player in neoplastic transformation of intestinal stem cells:protocadherin 8NIHNational Cancer Institute2021$76,000December 10, 2019November 30, 2022VAN LANDEGHEM, LAURIANNE CHANTALreporter.nih.gov
NCI PATTERNS OF CARE STUDY: DIAGNOSIS YEAR (2020 BREAST CANCER AND COLORECTAL CANCER)NIHNational Cancer Institute2023$75,887December 23, 2022December 22, 2023WEST, MICHELEreporter.nih.gov
Microbiota metabolites SCFA promote intestinal epithelial repair and wound healingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$72,468March 1, 2019February 28, 2023BILOTTA, ANTHONY Jreporter.nih.gov
NCI PATTERNS OF CARE STUDY - DIAGNOSIS YEAR 2020 BREAST CANCER AND COLORECTAL CANCERNIHNational Cancer Institute2023$71,719December 23, 2022December 22, 2023HERNANDEZ, BRENDAreporter.nih.gov
Exploiting Oncogenic Chromatin Regulators in Cancer Initiation and ProgressionNIHNational Cancer Institute2021 to 2022$71,638September 1, 2021August 31, 2023HYDER, USMANreporter.nih.gov
Immune-regulating MHC class I-like proteins and colorectal cancer riskNIHNational Cancer Institute2021$71,244March 1, 2020August 31, 2022PRIZMENT, ANNAreporter.nih.gov
Small-molecule Inhibition of Glycogen Synthase Kinase-3 Sensitizes Colorectal Cancer Cells and Stimulates Immune Cells to Bolster Immune Cell-mediated Tumor CytotoxicityNIHNational Cancer Institute2022 to 2023$70,682March 15, 2022May 31, 2023HUNTINGTON, KELSEY ELIZABETHreporter.nih.gov
Determining how the human gut microbiota modulates colon cancer tumorigenesisNIHNational Cancer Institute2021$70,458September 1, 2019August 31, 2022WEIS, ALLISONreporter.nih.gov
Detection of Colorectal Cancer Adaptive Mutability May Justify Combination of Targeted- and Immune-TherapiesNIHNational Cancer Institute2021$68,770September 20, 2021April 16, 2022YEATMAN, TIMOTHY Jreporter.nih.gov
Defining the contributions of WT RAS in RAS-mutant lung cancerNIHNational Cancer Institute2021$68,562January 2, 2019January 1, 2022STALNECKER, CLINT Areporter.nih.gov
Leveraging Metalloinsertors for the PET Imaging and Endoradiotherapy of MMR-Deficient CancersNIHNational Cancer Institute2022 to 2023$65,410August 15, 2022August 14, 2024DELANEY, SAMANTHA PATRICIAreporter.nih.gov
Top-down proteomic characterization of MEK/ERK in MAPK-driven cancersNIHNational Cancer Institute2021$63,738September 1, 2020August 14, 2022DROWN, BRYON SHANEreporter.nih.gov
Systems Approach to Dynamic Interplay between cAMP/PKA and ERK SignalingNIHNational Cancer Institute2022 to 2023$62,682March 1, 2022July 31, 2023POSNER, CLARA ANNEreporter.nih.gov
Small molecule inhibitors for the study of colibactin-induced carcinogenesis by gut microbesNIHNational Cancer Institute2021 to 2022$62,196February 1, 2020June 10, 2022VOLPE, MATTHEW ROBERTreporter.nih.gov
Defining the Boundaries of RNAi in a cellNIHNational Institute of General Medical Sciences2021 to 2022$60,788May 11, 2020May 10, 2023JOHNSON, KRYSTAL COURTNEYreporter.nih.gov
Development of Novel Herbal Therapy for Prevention of Irinotecan-induced Severe Delayed Onset DiarrheaNIHNational Center for Complementary & Integrative Health2021$52,000September 21, 2020September 20, 2022SINGH, RASHIMreporter.nih.gov
CLEAN: A community-engaged intervention to increase colorectal cancer screening in Chinese American immigrantsNIHNational Cancer Institute2022$51,530September 14, 2022January 31, 2023VANG, SUZANNE SHARRYreporter.nih.gov
Mechanisms of Transcriptional Regulation by MTG16 in the IntestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$51,036September 1, 2018April 30, 2023BROWN, RACHEL ELIZABETHreporter.nih.gov
Engineered Fibroblasts as Cell Therapy to Treat Colorectal Cancer via Tumor Stroma StabilizationNIHNational Cancer Institute2021$46,036August 1, 2020February 28, 2022JUNG, WEI-HUNGreporter.nih.gov
Engineering tumor-targeting bacteria to sense and deliver therapeuticsNIHNational Cancer Institute2021$46,036August 10, 2020July 31, 2022HARIMOTO, TETSUHIROreporter.nih.gov
Quantifying heterocellular communication and spatial intratumoral heterogeneity from high dimensional spatial proteomics dataNIHNational Cancer Institute2021$45,520September 1, 2020August 31, 2022FURMAN, SAMANTHA A.reporter.nih.gov
Combating Cetuximab Resistance in Colorectal CancerNIHNational Cancer Institute2021$43,397April 1, 2017March 31, 2022ZHANG, YUESHENGreporter.nih.gov
Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Bind, Placebo-Controlled Phase II to Phase III StudyNIHNational Cancer Institute2021$42,581January 10, 2019May 31, 2021SMITH, ELLEN MARY LAVOIEreporter.nih.gov
Effects of oxaliplatin-based chemotherapy on proprioception in cancer survivorsNIHNational Institute of Neurological Disorders and Stroke2021$42,252September 1, 2020August 31, 2022WANG, ALLISON BINGQINGreporter.nih.gov
Genome-wide Patterns of DNA Damage and Repair in Resistance to Platinum-Based ChemotherapyNIHNational Cancer Institute2021$41,629July 10, 2019May 31, 2022VAUGHN, COURTNEY MICHELLEreporter.nih.gov
Defining the role of microenvironmental ammonia in colorectal cancersNIHNational Cancer Institute2021 to 2022$40,225August 1, 2021August 2, 2022BELL, HANNAH NOELLEreporter.nih.gov
ROLE OF SORD IN SUGAR-MEDIATED CANCER METASTASISNIHNational Cancer Institute2022$38,297March 8, 2022July 7, 2022YUN, JIHYEreporter.nih.gov
Integrated Epidemiologic Study of Ultra-processed Foods and Colorectal Cancer SurvivalNIHNational Cancer Institute2022$36,141August 1, 2022July 31, 2023DU, MENGXIreporter.nih.gov
Inflammation Induced Cytosine Deamination and the Initiation of CancerNIHNational Cancer Institute2021$35,571July 1, 2018June 30, 2022HSU, CHIA WEIreporter.nih.gov
Investigating the role of the mitochondrial pyruvate carrier in colon tumorigenesisNIHNational Cancer Institute2021$31,138February 1, 2018May 22, 2021BENSARD, CLAIREreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Ut Southwestern Medical CenterDallas, TX9$26.2 million0$0
Albert Einstein College of MedicineBronx, NY6$23.6 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA14$14.7 million0$0
Case Western Reserve UniversityCleveland, OH11$14.5 million0$0
University of Southern CaliforniaLos Angeles, CA7$12.7 million0$0
Kaiser Foundation Research InstituteOakland, CA7$11.5 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY12$10.1 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK5$10.1 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA14$9.7 million0$0
University of Michigan at Ann ArborAnn Arbor, MI13$8 million0$0
Vanderbilt University Medical CenterNashville, TN9$7.9 million0$0
University of TX MD Anderson Can CTRHouston, TX14$7.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY10$6.7 million0$0
University of California, San DiegoLa Jolla, CA9$6.5 million0$0
Fred Hutchinson Cancer CenterSeattle, WA7$6.5 million0$0
University of ChicagoChicago, IL8$6.5 million0$0
Massachusetts General HospitalBoston, MA9$6.2 million0$0
University of UtahSalt Lake City, UT14$6 million0$0
Stanford UniversityStanford, CA8$5.9 million0$0
University of KentuckyLexington, KY9$5.1 million0$0
Ohio State UniversityColumbus, OH10$4.9 million0$0
Johns Hopkins UniversityBaltimore, MD7$4.8 million0$0
University of California, San FranciscoSan Francisco, CA5$4.5 million0$0
Duke UniversityDurham, NC6$4.3 million0$0
Mayo Clinic RochesterRochester, MN6$4.2 million0$0
University of PennsylvaniaPhiladelphia, PA11$4 million0$0
Oregon Health & Science UniversityPortland, OR3$3.9 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX4$3.8 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC6$3.4 million0$0
Indiana University IndianapolisIndianapolis, IN5$3.3 million0$0
Dartmouth CollegeHanover, NH3$3.2 million0$0
University of California-IrvineIrvine, CA3$3.1 million0$0
Boston Children's HospitalBoston, MA2$2.9 million0$0
University of FloridaGainesville, FL7$2.8 million0$0
Baylor College of MedicineHouston, TX5$2.7 million0$0
Dana-Farber Cancer InstBoston, MA4$2.7 million0$0
Washington UniversitySaint Louis, MO5$2.5 million0$0
RBHS -Cancer Institute of New JerseyNew Brunswick, NJ4$2.4 million0$0
University of California at DavisDavis, CA4$2.4 million0$0
New York University School of MedicineNew York, NY3$2.4 million0$0
Rush University Medical CenterChicago, IL2$2.2 million0$0
Beckman Research Institute/city of HopeDuarte, CA3$2.1 million0$0
Medical University of South CarolinaCharleston, SC2$2 million0$0
Sonoval LLCGaithersburg, MD1$2 million0$0
Morgan and Mendel Genomics, Inc.Wilmington, DE1$2 million0$0
HB Therapeutics, Inc.Indianapolis, IN1$2 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA3$2 million0$0
Quantitative Imaging Systems, LLCMonroeville, PA1$1.9 million0$0
University of WashingtonSeattle, WA3$1.9 million0$0
Massachusetts Institute of TechnologyCambridge, MA5$1.9 million0$0
University of Kansas Center for Research IncLawrence, KS1$1.8 million0$0
University of Nebraska Medical CenterOmaha, NE2$1.8 million0$0
University of LouisvilleLouisville, KY2$1.8 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY4$1.7 million0$0
Texas A&m Agrilife ResearchCollege Station, TX1$1.6 million0$0
Veterans Medical Research Fdn/san DiegoSan Diego, CA1$1.6 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM3$1.6 million0$0
Dimagi, Inc.Cambridge, MA1$1.5 million0$0
Brigham and Women's HospitalBoston, MA2$1.4 million0$0
North Carolina Central UniversityDurham, NC1$1.4 million0$0
University of Kansas Medical CenterKansas City, KS1$1.4 million0$0
University of Alabama at BirminghamBirmingham, AL3$1.3 million0$0
Northwestern UniversityChicago, IL3$1.3 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH3$1.3 million0$0
University of Texas at AustinAustin, TX2$1.3 million0$0
Yale UniversityNew Haven, CT3$1.3 million0$0
University of Connecticut SCH of Med/dntFarmington, CT4$1.3 million0$0
Iit Research InstituteChicago, IL1$1.3 million0$0
Methodist Hospital Research InstituteHouston, TX1$1.3 million0$0
Mayo Clinic JacksonvilleJacksonville, FL1$1.2 million0$0
Coriell Institute for Medical ResearchCamden, NJ1$1.1 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA4$1.1 million0$0
Purdue UniversityWest Lafayette, IN1$1.1 million0$0
Emory UniversityAtlanta, GA3$1.1 million0$0
Texas A&m University Health Science CTRCollege Station, TX1$1.1 million0$0
Information Management Services, Inc.Calverton, MD1$1 million0$0
Molecular Targeting Technologies, Inc.West Chester, PA1$1 million0$0
Actuated Medical, Inc.Bellefonte, PA1$999,9790$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA2$968,2100$0
Tulane University of LouisianaNew Orleans, LA2$948,4040$0
University of MinnesotaMinneapolis, MN3$873,9880$0
Iowa State UniversityAmes, IA1$867,7950$0
Dnatrix, Inc.Carlsbad, CA1$852,5680$0
Virginia State UniversityPetersburg, VA1$843,0340$0
Electronic Biosciences, Inc.San Diego, CA2$800,0000$0
University of South FloridaTampa, FL3$789,8480$0
Texas A&M Engineering Experiment StationCollege Station, TX2$763,9700$0
J. David Gladstone InstitutesSan Francisco, CA1$747,0000$0
Columbia University Health SciencesNew York, NY2$744,6320$0
Wake Forest University Health SciencesWinston-Salem, NC1$734,2520$0
Henry Ford Health SystemDetroit, MI1$709,9180$0
University of IowaIowa City, IA2$699,0320$0
University of Toledo Health Sci CampusToledo, OH1$696,8070$0
Rbhs-Robert Wood Johnson Medical SchoolPiscataway, NJ3$651,0040$0
General Electric Global Research CTRNiskayuna, NY1$645,7560$0
LSU Health Sciences CenterNew Orleans, LA2$644,5680$0
Geisinger ClinicDanville, PA1$637,6740$0
Harvard Medical SchoolBoston, MA3$626,2100$0
Vanderbilt UniversityNashville, TN4$611,0210$0
Augusta UniversityAugusta, GA3$604,8360$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20254$12,086,3140$0
20245$10,699,2970$0
2023162$64,145,2180$0
2022316$121,909,2990$0
2021410$165,050,8440$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.393November 2, 2026Not listedSame assistance listing 93.393 as 96 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)PAR-25-095NIH93.393November 6, 2026$350,000Same assistance listing 93.393 as 96 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)PAR-25-096NIH93.393November 17, 2026$200,000Same assistance listing 93.393 as 96 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.393November 20, 2026Not listedSame assistance listing 93.393 as 96 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.393January 7, 2027$375,000Same assistance listing 93.393 as 96 awards here
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)PAR-25-069NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 96 awards here
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)PAR-25-070NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 96 awards here
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)PAR-25-081NIH93.393January 7, 2027$499,999Same assistance listing 93.393 as 96 awards here
Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)PAR-25-167NIH93.393January 7, 2027Not listedSame assistance listing 93.393 as 96 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.393January 15, 2027$350,000Same assistance listing 93.393 as 96 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.393January 25, 2027Not listedSame assistance listing 93.393 as 96 awards here
Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)RFA-CA-26-010NIH93.393January 25, 2027Not listedSame assistance listing 93.393 as 96 awards here
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)RFA-CA-28-013NIH93.393February 9, 2027$700,000Same assistance listing 93.393 as 96 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.393April 5, 2027Not listedSame assistance listing 93.393 as 96 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.393April 5, 2027Not listedSame assistance listing 93.393 as 96 awards here
Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)PAR-28-057NIH93.393May 25, 2027$500,000Same assistance listing 93.393 as 96 awards here
Implementation and Evaluation of Databases to Examine AIDSRFA-AI-28-025NIH93.393May 27, 2027Not listedSame assistance listing 93.393 as 96 awards here
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)PAR-25-210NIH93.393June 2, 2027Not listedSame assistance listing 93.393 as 96 awards here
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)PAR-25-211NIH93.393June 2, 2027Not listedSame assistance listing 93.393 as 96 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)RFA-CA-28-003NIH93.393June 11, 2027$600,000Same assistance listing 93.393 as 96 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.