Data / Research funding / Chronic Pain
Chronic Pain: 2,747 NIH awards ($3.7B) to 502 organizations
2,747 NIH awards ($3.7B) in the NIH spending category Chronic Pain, to 502 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
The 500 largest of 2,747 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Center for Innovative TRIals in ChilDrEN and AdulTs (TRIDENT) | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $142,321,214 | September 23, 2022 | June 30, 2023 | BENJAMIN, DANIEL K. | reporter.nih.gov |
| NeuroTech Harbor: Seedling Cohort 3 | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $35,143,434 | September 30, 2022 | June 30, 2027 | SARMA, SRIDEVI V. | reporter.nih.gov |
| TARGET ENGAGEMENT OF INVESTIGATIONAL AGENTS IN PSPP | NIH | National Institute on Drug Abuse | 2021 to 2023 | $34,631,197 | September 15, 2023 | September 14, 2024 | GHAVAMI, AFSHIN | reporter.nih.gov |
| BPN-MCSP-HIT TO LEAD CHEMISTRY- MARTIN (NUVONURO) | NIH | National Institute on Drug Abuse | 2021 to 2025 | $25,707,343 | December 9, 2024 | June 8, 2026 | MICHELS, PETER C | reporter.nih.gov |
| SCREENING OF INVESTIGATIONAL AGENTS THROUGH THE NINDS PRECLINICAL SCREENING PLATFORM FOR PAIN (PSPP) | NIH | National Institute on Drug Abuse | 2024 to 2025 | $21,254,211 | September 6, 2024 | September 5, 2026 | HANANIA, TALEEN | reporter.nih.gov |
| West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $20,261,619 | September 30, 2001 | July 31, 2029 | JOSHI, TRUPTI | reporter.nih.gov |
| EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $19,316,294 | January 1, 2021 | July 31, 2026 | FAVA, MAURIZIO | reporter.nih.gov |
| BIOLOGICS IDIQ TASK ORDER- NON-GLP TOXICITY AND TOXICOKINETIC STUDIES IN RODENTS AND NON-RODENTS FOR A NOVEL, SUBCUTANEOUSLY-DOSED MODIFIED-HEPARIN DRUG | NIH | National Institute on Drug Abuse | 2022 to 2025 | $14,836,664 | September 29, 2025 | September 28, 2026 | reporter.nih.gov | |
| HEAL ERN: Data Coordinating Resource Center | NIH | National Center for Advancing Translational Sciences | 2022 to 2025 | $13,821,158 | September 23, 2022 | August 31, 2027 | WATT, KEVIN M | reporter.nih.gov |
| Integrated Care for Chronic Pain and Opioid Use Disorder: The IMPOWR Research Center at Montefiore/Einstein (IMPOWR-ME) | NIH | National Institute on Drug Abuse | 2021 to 2025 | $13,727,424 | September 30, 2021 | July 31, 2027 | STARRELS, JOANNA L. | reporter.nih.gov |
| HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers | NIH | National Institute on Drug Abuse | 2021 to 2025 | $12,902,047 | September 30, 2021 | July 31, 2026 | BECKER, WILLIAM C | reporter.nih.gov |
| Tailored Retention and Engagement for Effective integrated Treatment of OUD and Pain (TREETOP) | NIH | National Institute on Drug Abuse | 2021 to 2025 | $12,656,947 | September 30, 2021 | July 31, 2027 | WINSTANLEY, ERIN L | reporter.nih.gov |
| Center for Addiction and Disease Risk Exacerbation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $12,487,946 | August 1, 2019 | July 31, 2029 | MONTI, PETER M. | reporter.nih.gov |
| Mapping the joint-nerve interactome of the knee | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $11,877,917 | September 23, 2022 | August 31, 2027 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| CGMP MANUFACTURE OF VHCA8* FOR THE TREATMENT OF PAIN | NIH | National Institute on Drug Abuse | 2022 to 2025 | $11,758,351 | March 11, 2024 | April 29, 2027 | MAYER, CHRISTINA | reporter.nih.gov |
| Site-Directed RNA Editing of Nav1.7 as a Novel Analgesic | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $11,194,636 | September 23, 2021 | August 31, 2027 | ROSENTHAL, JOSHUA J.C. | reporter.nih.gov |
| From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $11,100,837 | September 22, 2022 | August 31, 2027 | WAINGER, BRIAN JASON | reporter.nih.gov |
| Innervation of the knee and TMJ | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $10,814,779 | September 23, 2022 | August 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Increasing the Efficiency of RE-JOIN Through Data Sharing and Integration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $10,788,004 | September 23, 2022 | July 31, 2027 | LEE, BRENDAN | reporter.nih.gov |
| HEAL Clinical Coordinating Resource Center for the Pain Management Effectiveness Research Network | NIH | National Center for Advancing Translational Sciences | 2022 to 2025 | $10,761,545 | September 23, 2022 | August 31, 2027 | BENJAMIN, DANIEL K. | reporter.nih.gov |
| Data Center for Acute to Chronic Pain Biosignatures | NIH | National Institute on Drug Abuse | 2021 to 2025 | $10,727,611 | September 1, 2019 | July 31, 2027 | LINDQUIST, MARTIN | reporter.nih.gov |
| A sequenced-strategy for improving outcomes in patients with knee osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $10,487,739 | September 25, 2019 | August 31, 2025 | CAMPBELL, CLAUDIA MICHELLE | reporter.nih.gov |
| Integrative Treatment for Achieving Holistic Recovery from Comorbid Chronic Pain and Opioid Use Disorder | NIH | National Institute on Drug Abuse | 2021 to 2025 | $10,475,915 | September 30, 2021 | July 31, 2027 | WITKIEWITZ, KATIE A | reporter.nih.gov |
| NIH Health Care Systems Research Collaboratory-Coordinating Center (U24) | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $10,249,994 | September 22, 2022 | May 31, 2028 | HERNANDEZ, ADRIAN | reporter.nih.gov |
| Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRE | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $9,739,425 | September 1, 2022 | April 30, 2027 | GLADWIN, MARK T | reporter.nih.gov |
| Defining Mechanisms of Pain Relief Associated with Dorsal Root Ganglion and Spinal Cord Stimulation | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $9,610,931 | September 17, 2022 | August 31, 2027 | KOERBER, H RICHARD | reporter.nih.gov |
| Neural Architecture of the Murine and Human Temporomandibular Joint | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $9,483,860 | September 23, 2022 | August 31, 2027 | DONNELLY, CHRISTOPHER RYAN | reporter.nih.gov |
| University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $9,423,992 | September 21, 2022 | August 31, 2027 | WILLIAMS, DAVID A | reporter.nih.gov |
| A novel therapeutic to ameliorate chronic pain and reduce opiate use | NIH | National Institute on Drug Abuse | 2021 to 2024 | $9,323,255 | March 15, 2019 | June 30, 2024 | TABAKOFF, BORIS | reporter.nih.gov |
| Human Nociceptor and Spinal Cord Molecular Signature Center | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $9,264,871 | September 19, 2022 | August 31, 2027 | PRICE, THEODORE J. | reporter.nih.gov |
| Johns Hopkins-Tufts Trial Innovation Center HEAL Pain ERN Supplement | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $8,842,412 | July 1, 2016 | June 30, 2023 | HANLEY, DANIEL F | reporter.nih.gov |
| Toward Next Generation Data on Health and Life Changes at Older Ages | NIH | National Institute on Aging | 2021 to 2022 | $8,740,462 | September 30, 2017 | June 30, 2023 | KAPTEYN, ARIE | reporter.nih.gov |
| Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH) - HEAL Supplement | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $8,727,151 | July 1, 2016 | June 30, 2023 | HARRIS, PAUL A. | reporter.nih.gov |
| EPPIC-NET DCC - Supplement | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $8,306,997 | September 1, 2023 | August 31, 2025 | TROXEL, ANDREA B | reporter.nih.gov |
| Back Pain Consortium (BACPAC) Research Program Data Integration, Algorithm Development and Operations Management Center | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $8,257,593 | September 26, 2019 | August 31, 2025 | ANSTROM, KEVIN J | reporter.nih.gov |
| Tailored Non-Pharmacotherapy Services for Chronic Pain: Testing Scalable and Pragmatic Approaches - Admin Supplement | NIH | National Institute on Aging | 2021 to 2023 | $8,205,902 | September 30, 2019 | August 31, 2025 | DEBAR, LYNN L. | reporter.nih.gov |
| Comprehensive functional phenotyping of trigeminal neurons innervating temporomandibular joint (TMJ) tissues in male female and aged mice primates and humans with and without TMJ disorders (TMJD) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $8,002,252 | September 23, 2022 | August 31, 2027 | AKOPIAN, ARMEN N | reporter.nih.gov |
| The Osteoarthritis Prevention Study (TOPS) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $7,779,027 | August 10, 2023 | July 31, 2028 | MESSIER, STEPHEN P | reporter.nih.gov |
| PURPOSE: Positively Uniting Researchers of Pain to Opine, Synthesize, and Engage | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $7,732,800 | September 28, 2022 | March 21, 2025 | COVERSTONE, JACOB SUTTON | reporter.nih.gov |
| Transition from Acute to Chronic Pain After Thoracic Surgery | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $7,656,419 | August 1, 2020 | July 31, 2024 | BRUMMETT, CHAD M | reporter.nih.gov |
| Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $7,501,613 | August 15, 2019 | July 31, 2025 | SLUKA, KATHLEEN A | reporter.nih.gov |
| Daily & Localized NSAID Sonophoresis for Symptomatic Treatment of Knee Osteoarthritis | NIH | National Institute on Aging | 2021 to 2025 | $7,422,310 | September 20, 2024 | May 31, 2027 | LEWIS, GEORGE KENNETH | reporter.nih.gov |
| Boston Alcohol Research Collaboration on HIV/AIDS - Comorbidity Center (Boston ARCH CC) | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $7,406,307 | September 22, 2021 | August 31, 2027 | STEIN, MICHAEL D | reporter.nih.gov |
| NIH-DOD-VA Pain Management Collaboratory Coordinating Center | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $7,344,466 | September 20, 2017 | July 31, 2030 | BECKER, WILLIAM C | reporter.nih.gov |
| Johns Hopkins Statistical and Safety Resource Center-HEAL PAIN ERN | NIH | National Center for Advancing Translational Sciences | 2022 to 2025 | $7,209,820 | September 23, 2022 | August 31, 2027 | HANLEY, DANIEL F | reporter.nih.gov |
| Understanding the Mechanistic, Neurophysiological, and Antinociceptive Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $7,138,197 | September 15, 2022 | July 31, 2027 | WILKES, DENISE | reporter.nih.gov |
| Sensory Phenotyping to Enhance Neuropathic Pain Drug Development | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $7,081,684 | September 21, 2023 | August 31, 2028 | FREEMAN, ROY | reporter.nih.gov |
| Pterygopalatine Fossa (PPF) Block as an Opioid Sparing Treatment for AcuteHeadache in Aneurysmal Subarachnold Hemorrhage | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $7,048,922 | March 15, 2023 | February 28, 2027 | BUSL, KATHARINA MARIA | reporter.nih.gov |
| 1/2 IMPACt-LBP CCC | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $6,933,572 | July 15, 2021 | July 31, 2027 | GOERTZ, CHRISTINE MARIE | reporter.nih.gov |
| IMPACT: Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $6,889,914 | September 21, 2023 | August 31, 2028 | KING, JEAN A | reporter.nih.gov |
| Optimizing Pain Treatment In Children On Mechanical ventilation (OPTICOM) | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $6,866,353 | September 5, 2024 | August 31, 2029 | TRAUBE, CHANI | reporter.nih.gov |
| Unravelling Mechanisms and Novel Therapeutic Targets for Peripheral Neuropathy and Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $6,767,963 | December 15, 2017 | November 30, 2025 | WOOLF, CLIFFORD J | reporter.nih.gov |
| Implementing and Personalizing Best-In-Class Opioid-sparing Pain Management for Major Inpatient Surgeries in Children | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $6,720,269 | September 5, 2024 | August 31, 2029 | SADHASIVAM, SENTHILKUMAR | reporter.nih.gov |
| Novel, Non-Opioid, Non-Addictive Intrathecal Therapy for the Treatment of Chronic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $6,612,268 | September 30, 2021 | January 31, 2026 | CAMPBELL, JAMES N | reporter.nih.gov |
| Mechanisms of Action of Peripheral Nerve Stimulation for the Treatment of Chronic Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $6,522,833 | September 20, 2023 | August 31, 2026 | HAH, JENNIFER | reporter.nih.gov |
| Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $6,352,490 | September 21, 2020 | August 31, 2025 | DOORENBOS, ARDITH Z | reporter.nih.gov |
| Clinical Translation of Ultrasonic Ketamine Uncaging for Non-Opioid Therapy of Chronic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $6,205,798 | September 30, 2019 | May 31, 2026 | AIRAN, RAAG D | reporter.nih.gov |
| Scheduled Prophylactic 6-hourly IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients (PANDORA) - Administrative Supplement | NIH | National Institute on Aging | 2021 to 2025 | $6,139,069 | September 30, 2019 | November 30, 2026 | SUBRAMANIAM, BALACHUNDHAR | reporter.nih.gov |
| Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy | NIH | National Cancer Institute | 2021 to 2025 | $6,132,390 | May 6, 2021 | April 30, 2027 | KOLB, NOAH ALLAN | reporter.nih.gov |
| BackInAction Administrative Supplement | NIH | National Center for Complementary & Integrative Health | 2021 to 2022 | $6,098,263 | September 28, 2019 | August 31, 2025 | DEBAR, LYNN L. | reporter.nih.gov |
| Group-Based Mindfulness for Patients with Chronic Low Back Pain in the Primary Care | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $6,091,168 | September 28, 2019 | August 31, 2025 | MORONE, NATALIA E. | reporter.nih.gov |
| Personalized Auricular Point Acupressure for Chronic Pain Self-Management in Rural Populations | NIH | National Center for Complementary & Integrative Health | 2025 | $5,982,014 | September 4, 2024 | August 31, 2029 | KAWI, JENNIFER | reporter.nih.gov |
| MIRHIQL Resource Center for Improving Quality of Life with Chronic Pain (MRC) | NIH | National Institute on Drug Abuse | 2023 | $5,978,096 | August 15, 2023 | July 31, 2028 | ADAMS, MEREDITH C. B. | reporter.nih.gov |
| Natural products as probes of the pain pathway | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,820,560 | December 15, 2017 | November 30, 2025 | JULIUS, DAVID | reporter.nih.gov |
| Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic Trial | NIH | National Center for Complementary & Integrative Health | 2024 to 2025 | $5,587,756 | May 19, 2023 | August 31, 2028 | WANG, CHENCHEN | reporter.nih.gov |
| Transition from Acute to Chronic Pain in Total Knee Arthroplasty Patients: Identifying Resilience and Vulnerability Profiles | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $5,585,899 | April 1, 2022 | July 31, 2025 | BURNS, JOHN W. | reporter.nih.gov |
| Development and Optimization of MNK Inhibitors for the Treatment of Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $5,575,218 | September 1, 2021 | August 31, 2025 | SAHN, JAMES JEFFREY | reporter.nih.gov |
| Understanding neural control of the ocular surface | NIH | National Eye Institute | 2022 to 2025 | $5,561,710 | September 30, 2022 | August 31, 2027 | JENKINS, MICHAEL W. | reporter.nih.gov |
| Headache Assessment of Children for Emergent Intracranial Abnormalities | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $5,351,391 | September 1, 2020 | June 30, 2025 | TSZE, DANIEL SING-KWONG | reporter.nih.gov |
| Development of a Potent and Selective Nav1.8 inhibitor for the Treatment of Acute and Chronic Pain with the Goal of Reducing Opioid Use and Preventing Opioid Use Disorders | NIH | National Institute on Drug Abuse | 2023 | $5,341,667 | May 15, 2023 | April 30, 2025 | HUNTER, JOHN CURETON | reporter.nih.gov |
| Gut Microbiome and Individual Differences in Lumbosacral Radicular Pain | NIH | National Center for Complementary & Integrative Health | 2025 | $5,318,433 | August 15, 2025 | July 31, 2029 | SHEN, SHIQIAN | reporter.nih.gov |
| Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in Veterans | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $5,266,106 | January 1, 2024 | December 31, 2025 | SEAL, KAREN H | reporter.nih.gov |
| Optimizing the use of ketamine to reduce chronic postsurgical pain | NIH | National Cancer Institute | 2021 to 2024 | $5,247,593 | September 17, 2021 | August 31, 2025 | WANG, JING | reporter.nih.gov |
| High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,225,127 | January 1, 2025 | April 30, 2025 | MCLAUGHLIN, BRYAN L | reporter.nih.gov |
| IGNITE EP2 - Admin Supplement | NIH | National Human Genome Research Institute | 2021 to 2024 | $5,199,656 | July 1, 2024 | June 30, 2025 | CAVALLARI, LARISA HUMMA | reporter.nih.gov |
| Tele-Collaborative Outreach to Rural Patients with Chronic Pain: The CORPs Trial | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $5,197,675 | September 14, 2022 | August 31, 2027 | LOVEJOY, TRAVIS IAN | reporter.nih.gov |
| Trigeminal nociceptors: Neural intersection of chronic pain and alveolar bone remodeling | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $5,140,671 | September 8, 2020 | June 30, 2028 | CHUNG, MAN-KYO | reporter.nih.gov |
| Central and Peripheral Mechanisms of Corneal Pain | NIH | National Eye Institute | 2022 to 2025 | $5,081,730 | September 30, 2022 | August 31, 2027 | MENG, IAN D | reporter.nih.gov |
| MODEL-pain MOdeling Diverse Experiences and Longitudinal trajectories of pain | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $5,057,591 | September 12, 2025 | August 31, 2029 | PUNCHES, BRITTANY E | reporter.nih.gov |
| Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents | NIH | National Eye Institute | 2022 to 2025 | $5,054,648 | September 30, 2022 | August 31, 2027 | SABAN, DANIEL RAPHAEL | reporter.nih.gov |
| Nonpharmacologic Pain Management in FQHC primary care clinics | NIH | National Institute of Nursing Research | 2021 to 2024 | $4,905,424 | September 25, 2020 | August 31, 2026 | FRITZ, JULIE M | reporter.nih.gov |
| Leveraging inter-individual differences in walking pain and impairment to elucidate whole-person mechanisms of knee osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $4,899,748 | September 19, 2025 | August 31, 2029 | ALTER, BENEDICT J | reporter.nih.gov |
| Understanding vulvodynia: Using machine-learning-based modeling to identify factors associated with resolution and persistence of vulvar pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $4,867,750 | August 26, 2025 | June 30, 2030 | MITCHELL, CAROLINE M | reporter.nih.gov |
| Endosomal mechanisms signaling oral cancer pain | NIH | National Institute of Dental & Craniofacial Research | 2023 | $4,820,611 | September 19, 2023 | August 31, 2026 | SCHMIDT, BRIAN L | reporter.nih.gov |
| HEALing LB3P: Profiling Biomechanical, Biological and Behavioral phenotypes | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $4,810,232 | September 26, 2019 | August 31, 2025 | SOWA, GWENDOLYN A | reporter.nih.gov |
| Implementation Facilitation of Screening, Brief Intervention, and Referral to Treatment for Pain Management for Veterans Separating from Military Service | NIH | National Center for Complementary & Integrative Health | 2024 to 2025 | $4,796,168 | July 1, 2023 | August 31, 2028 | ROSEN, MARC I | reporter.nih.gov |
| Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial | NIH | National Cancer Institute | 2023 to 2025 | $4,784,222 | September 6, 2022 | August 31, 2027 | CHEVILLE, ANDREA LYNNE | reporter.nih.gov |
| Integrating Nonpharmacologic Strategies for Pain with Inclusion, Respect, and Equity (INSPIRE): Tailored digital tools, telehealth coaching, and primary care coordination | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,783,072 | August 15, 2022 | July 31, 2027 | SATTERFIELD, JASON M | reporter.nih.gov |
| Actigraphy Enhanced Clinical Chronic Lower Back Pain Management | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,765,363 | September 15, 2021 | July 31, 2027 | KRUGER, GRANT H | reporter.nih.gov |
| AIM BACK UH3 Transition | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $4,729,831 | September 20, 2017 | February 28, 2026 | GEORGE, STEVEN Z | reporter.nih.gov |
| Clinical Coordinating Center for the Health Initiative in Early Phase Pain Investigation Clinical Network | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $4,660,324 | September 30, 2019 | August 31, 2025 | FAVA, MAURIZIO | reporter.nih.gov |
| Network modeling as a unified framework to understand inter-individual differences in chronic musculoskeletal pain | NIH | National Center for Complementary & Integrative Health | 2025 | $4,649,740 | August 15, 2025 | July 31, 2029 | SIKDAR, SIDDHARTHA | reporter.nih.gov |
| Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy - Yale Resource Center (MIRHIQL-YRC) | NIH | National Institute on Drug Abuse | 2023 | $4,626,338 | August 15, 2023 | July 31, 2026 | BECKER, WILLIAM C | reporter.nih.gov |
| Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid Analgesics | NIH | National Institute on Drug Abuse | 2024 to 2025 | $4,623,799 | September 30, 2019 | December 31, 2026 | CORTES-PUCH, IRENE | reporter.nih.gov |
| IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain after Surgery | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,618,885 | September 18, 2024 | August 31, 2027 | HAROUTOUNIAN, SIMON | reporter.nih.gov |
| Neural Mechanisms of Colored Light Driven Analgeisa | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,572,599 | September 19, 2024 | August 31, 2027 | MAUCK, MATTHEW CHRISTOPHER | reporter.nih.gov |
| UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $4,545,348 | September 25, 2019 | August 31, 2025 | LOTZ, JEFFREY C. | reporter.nih.gov |
| Partners for Pain & Wellbeing Equity: A Randomized Trial of Community Supported Complementary and Integrative Health Self Management for Back Pain | NIH | National Center for Complementary & Integrative Health | 2024 | $4,532,340 | September 19, 2022 | August 31, 2027 | EVANS, RONI L. | reporter.nih.gov |
| Behavioral and Psychosocial Effects on Study Outcomes in End-Stage Cancer Treatment (BEST End-Stage Cancer Study) | NIH | National Cancer Institute | 2021 to 2025 | $4,525,183 | September 1, 2015 | July 31, 2029 | PRIGERSON, HOLLY GWEN | reporter.nih.gov |
| Clinical Optimization of Ultrasonic Drug Delivery Technologies for US Veteran Populations that Experience Health Disparities with Arthritis and Chronic Pain | NIH | National Institute on Minority Health and Health Disparities | 2023 to 2025 | $4,518,543 | September 14, 2020 | February 28, 2026 | LEWIS, GEORGE KENNETH | reporter.nih.gov |
| Interdisciplinary Center of Excellence for the Study of Pain and Sensory Function | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $4,486,170 | June 1, 2022 | May 31, 2027 | MENG, IAN D | reporter.nih.gov |
| Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients with Chronic Pain | NIH | National Institute of Nursing Research | 2025 | $4,451,386 | August 1, 2025 | July 31, 2028 | TONG, SEBASTIAN | reporter.nih.gov |
| Meaningful data integration, visualization and distribution for Human Pain Associated Genes & Cells Datasets | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,446,277 | September 30, 2023 | August 31, 2026 | WAGENAAR, JOOST B | reporter.nih.gov |
| Non-pharmacological Options in postoperative Hospital-based And Rehabilitation pain Management (NOHARM) pragmatic clinical trial | NIH | National Institute on Aging | 2021 to 2023 | $4,429,006 | September 30, 2019 | August 31, 2025 | CHEVILLE, ANDREA LYNNE | reporter.nih.gov |
| Sodium and Calcium Channels: Structure, Function, Neuroplasticity, and Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $4,413,116 | May 1, 2019 | April 30, 2025 | SCOTT, JOHN D | reporter.nih.gov |
| Translating an MR-guided focused ultrasound system for first-in-human precision neuromodulation of pain circuits | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,364,294 | September 20, 2023 | August 31, 2026 | CASKEY, CHARLES F | reporter.nih.gov |
| WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use Disorder | NIH | National Institute on Drug Abuse | 2022 to 2025 | $4,339,941 | September 30, 2022 | August 31, 2028 | ADAMS, MEREDITH C. B. | reporter.nih.gov |
| Biased Mu-Opioid Receptor Analgesics to Prevent Overdose and Opioid Use Disorders | NIH | National Institute on Drug Abuse | 2021 to 2023 | $4,306,927 | September 15, 2018 | August 31, 2023 | KUO, LAWRENCE C | reporter.nih.gov |
| Bioactive lipids as effectors and indicators of the deleterious effects of environmental exposure on chronic diseases | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $4,304,396 | June 15, 2019 | April 30, 2027 | MORISSEAU, CHRISTOPHE HP | reporter.nih.gov |
| Preclinical optimization of a gene therapy for erythromelalgia and chronic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $4,279,361 | June 1, 2021 | May 31, 2025 | ALEMAN GUILLEN, FERNANDO | reporter.nih.gov |
| Cornell Roybal Center-Translational Research Institute on Pain in Later Life | NIH | National Institute on Aging | 2021 to 2025 | $4,228,788 | September 30, 2003 | May 31, 2029 | REID, MANNEY CARRINGTON | reporter.nih.gov |
| Small molecule targeting an epigenetic regulator for the treatment of osteoarthritis | NIH | National Institute on Aging | 2021 to 2024 | $4,178,124 | September 30, 2021 | May 2, 2025 | ADORNO, MADDALENA | reporter.nih.gov |
| Neuronal and Network Mechanisms of Electrocortical Stimulation | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,175,793 | August 15, 2023 | July 31, 2026 | SLUTZKY, MARC W. | reporter.nih.gov |
| Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK) Study | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $4,171,920 | September 1, 2017 | July 31, 2024 | BRONFORT, GERT | reporter.nih.gov |
| Integrated Omics Analysis of Pain: Omics Data Generation Center | NIH | National Institute on Drug Abuse | 2021 to 2025 | $4,167,733 | September 1, 2019 | July 31, 2027 | OLIVIER, MICHAEL | reporter.nih.gov |
| Elucidating Factors Contributing to Disparities in Neurobiological Vulnerabilities and Alzheimers Disease and Related Dementias Risk | NIH | National Institute on Aging | 2021 to 2023 | $4,137,397 | April 1, 2009 | February 28, 2025 | FILLINGIM, ROGER B | reporter.nih.gov |
| Opiod Analgesic Reduction Study (OARS): Managing Acute Post-Operative Surgical Pain | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2023 | $4,090,798 | August 1, 2020 | July 31, 2025 | FELDMAN, CECILE | reporter.nih.gov |
| Pain Mechanisms in Fabry Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,085,512 | May 15, 2019 | March 31, 2026 | STUCKY, CHERYL LOUISE | reporter.nih.gov |
| SPRINT: Signature for Pain Recovery IN Teens | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $4,074,189 | September 30, 2019 | July 31, 2025 | SIMONS, LAURA E | reporter.nih.gov |
| A fully humanized functional genomic screen to identify and validate pain therapeutic targets | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $4,039,366 | September 1, 2025 | August 31, 2028 | PRICE, THEODORE J. | reporter.nih.gov |
| Integrative Training Program for Pediatric Sickle Cell Pain | NIH | National Center for Complementary & Integrative Health | 2024 | $4,030,343 | September 19, 2022 | August 31, 2027 | SIL, SOUMITRI | reporter.nih.gov |
| A Layered Examination of the Patient Experience to Elucidate the Role of Palliative Care in Surgical Care for Seriously Ill Older Adults | NIH | National Institute on Aging | 2021 to 2025 | $4,002,174 | August 1, 2021 | April 30, 2026 | COOPER, ZARA R | reporter.nih.gov |
| ICERCH-Supporting the HEAL Pain ERN | NIH | National Center for Advancing Translational Sciences | 2022 to 2025 | $3,992,010 | September 24, 2022 | August 31, 2027 | HARRIS, PAUL A. | reporter.nih.gov |
| Technology Research Site for Advanced, Faster Quantitative Imaging for BACPAC | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $3,960,533 | September 26, 2019 | July 31, 2025 | MAJUMDAR, SHARMILA | reporter.nih.gov |
| RELAXaHEAD: A Behavioral Approach to Remote Migraine Management in Primary Care | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $3,954,279 | September 23, 2022 | August 31, 2028 | MINEN, MIA | reporter.nih.gov |
| Targeting HB-EGF and trigeminal EGFR for oral cancer pain and opioid tolerance | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $3,950,748 | September 19, 2022 | September 18, 2027 | YE, YI | reporter.nih.gov |
| PNPase inhibition as an effective treatment for chronic bladder pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $3,942,335 | September 24, 2022 | August 31, 2027 | BIRDER, LORI A | reporter.nih.gov |
| Evaluation of Cannabidiol for Reduction of Brain Neuroinflammation | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,931,875 | June 1, 2021 | March 31, 2027 | LOGGIA, MARCO LUCIANO | reporter.nih.gov |
| The Center for Innovation and Translation of Point of Care Technologies for Expanded Cancer Care Access (CITEC) | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $3,900,000 | September 13, 2023 | July 31, 2028 | RICHARDS-KORTUM, REBECCA R. | reporter.nih.gov |
| Osteoarthritis Progression And Sensory Pathway Alterations | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,899,677 | May 1, 2013 | July 31, 2029 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer. | NIH | National Institute of Dental & Craniofacial Research | 2025 | $3,892,146 | September 1, 2025 | August 31, 2029 | LI, XIN | reporter.nih.gov |
| The Spine Phenome Project: Enhancing Patient Diversity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $3,879,795 | September 26, 2019 | August 31, 2024 | MARRAS, WILLIAM STEVEN | reporter.nih.gov |
| Multisite adaptive brain stimulation for multidimensional treatment of refractory chronic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $3,850,834 | September 30, 2019 | July 31, 2025 | SHIRVALKAR, PRASAD | reporter.nih.gov |
| Chiropractic Care for Veterans: A Pragmatic Randomized Trial Addressing Dose Effects for cLBP | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $3,826,274 | September 20, 2017 | August 31, 2025 | LONG, CYNTHIA R | reporter.nih.gov |
| Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $3,808,274 | April 7, 2022 | June 30, 2028 | VISWANATHAN, ASHWIN | reporter.nih.gov |
| Molecular genetic mechanisms of opioid receptor signaling | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,788,093 | September 15, 2019 | April 30, 2029 | GRILL, BROCK | reporter.nih.gov |
| Group-based Integrative Pain Management: A multi-level approach to address intersectional stigma and social isolation in diverse primary care safety net patients with chronic pain | NIH | National Institute on Minority Health and Health Disparities | 2024 | $3,752,243 | August 12, 2022 | April 30, 2027 | CHAO, MARIA T | reporter.nih.gov |
| Omics Data Generation Center (ODGC) for the Acute to Chronic Pain Signatures (A2CPS) Program | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,741,527 | September 1, 2019 | July 31, 2027 | LAURENT, LOUISE CHANG | reporter.nih.gov |
| Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $3,735,563 | August 10, 2023 | July 31, 2028 | ROLLMAN, BRUCE LAWRENCE | reporter.nih.gov |
| Differentiation of Clinical Phenotypes of Inflammatory and Neuropathic Ocular Pain Conditions with Morphologic Measures and Functional Brain Imaging | NIH | National Eye Institute | 2022 to 2025 | $3,722,281 | September 30, 2022 | August 31, 2027 | MOULTON, ERIC ALAN | reporter.nih.gov |
| PSP Omics Center of Acute to Chronic Pain Signatures | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,716,997 | September 1, 2019 | July 31, 2027 | JACOBS, JON | reporter.nih.gov |
| CNS Pain Mechanisms in Early Rheumatoid Arthritis: Implications for the Acute to Chronic Pain Transition | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,704,355 | July 1, 2013 | April 30, 2027 | LEE, YVONNE CLAIRE | reporter.nih.gov |
| From the spinal cord to the brain: Neurology of the pain and itch neurons | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,643,601 | December 1, 2016 | November 30, 2024 | BASBAUM, ALLAN I. | reporter.nih.gov |
| The Role of Implicit Bias on Outcomes of Patients with Advanced Solid Cancers | NIH | National Cancer Institute | 2021 to 2025 | $3,605,222 | May 18, 2022 | March 31, 2026 | SMITH, CARDINALE B | reporter.nih.gov |
| Supplement-Discovery and Validation of Epigenetic Biomarkers in Brain Tissue | NIH | National Institute on Aging | 2021 to 2024 | $3,602,826 | May 15, 2020 | February 28, 2026 | CRUZ-ALMEIDA, YENISEL | reporter.nih.gov |
| Peripheral blood mononuclear cell epigenetic associations in and biomarkers for knee osteoarthritis development and progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,596,032 | June 16, 2020 | August 31, 2028 | JEFFRIES, MATLOCK | reporter.nih.gov |
| Implementing genomic medicine through pragmatic trials in diverse and underserved populations across Indiana. | NIH | National Human Genome Research Institute | 2021 to 2024 | $3,584,747 | September 19, 2018 | June 30, 2025 | SKAAR, TODD C. | reporter.nih.gov |
| Cannabidiol for postoperative Opioid Reduction in primary total Knee arthroplasty – a randomized, 2x2 factorial, double-blind, placebo-controlled clinical trial (The CORK trial) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $3,579,362 | September 18, 2023 | August 31, 2028 | BRUMMETT, CHAD M | reporter.nih.gov |
| Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention (RAMP-WH) | NIH | National Institute of Nursing Research | 2025 | $3,568,521 | August 1, 2025 | July 31, 2028 | BURGESS, DIANA J | reporter.nih.gov |
| 1/2 Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE Trial) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $3,567,710 | May 15, 2019 | August 31, 2022 | GLADWIN, MARK T | reporter.nih.gov |
| Transspinal Magnetic Stimulation for the Treatment of Neuropathic Pain | NIH | National Institute of Biomedical Imaging and Bioengineering | 2024 | $3,565,780 | September 18, 2024 | August 31, 2027 | BONMASSAR, GIORGIO | reporter.nih.gov |
| Development and validation of a porcine model of spinal cord injury-induced neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $3,560,956 | September 21, 2023 | August 31, 2026 | FLOYD, CANDACE L. | reporter.nih.gov |
| 2/2: IMPACt-LBP DCC | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,548,007 | July 15, 2021 | June 30, 2027 | CHAKRABORTY, HRISHIKESH | reporter.nih.gov |
| Addressing the chronic pain epidemic among older adults in underserved community center; The GetActive+ study. | NIH | National Institute on Aging | 2024 | $3,542,451 | September 1, 2022 | August 31, 2027 | VRANCEANU, ANA-MARIA | reporter.nih.gov |
| Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal Biomechanics | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,536,892 | July 14, 2016 | June 30, 2027 | MAJUMDAR, SHARMILA | reporter.nih.gov |
| Opioid therapy for pain in individuals with metastatic cancer: benefits, harms and stakeholder perspectives | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,491,253 | September 15, 2021 | June 30, 2027 | WHITE, GRETCHEN | reporter.nih.gov |
| SmartStim, a novel implantable neuromodulation system to cure chronic pain. | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $3,473,616 | August 15, 2025 | July 31, 2028 | FENG, BIN | reporter.nih.gov |
| Center for chronic pain and drug abuse | NIH | National Institute on Drug Abuse | 2021 to 2022 | $3,471,757 | September 1, 2018 | June 30, 2025 | APKARIAN, APKAR VANIA | reporter.nih.gov |
| Mechanisms of Pain and Photophobia in Migraine and Dry Eye | NIH | National Eye Institute | 2022 to 2025 | $3,466,540 | September 30, 2022 | August 31, 2027 | AICHER, SUE A | reporter.nih.gov |
| Integrated, Individualized, and Intelligent Prescribing (I3P) Clinical Trial Network | NIH | National Human Genome Research Institute | 2021 to 2024 | $3,458,289 | July 1, 2024 | June 30, 2025 | PETERSON, JOSEPH F. | reporter.nih.gov |
| More than a Movement Disorder: Applying Palliative Care to Parkinson's Disease and Lewy Body Dementias | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,433,868 | September 15, 2016 | September 30, 2026 | KLUGER, BENZI M | reporter.nih.gov |
| Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous system | NIH | National Cancer Institute | 2021 to 2025 | $3,433,365 | July 1, 2021 | June 30, 2027 | BOTA, DANIELA ANNENELIE | reporter.nih.gov |
| SMART Stepped Care Management for Low Back Pain in Military Health System | NIH | National Center for Complementary & Integrative Health | 2021 to 2022 | $3,420,219 | September 20, 2017 | August 31, 2025 | FRITZ, JULIE M | reporter.nih.gov |
| Characterizing the Complexity of Advanced Cancer Pain in the Home Context by Leveraging Smart Health Technology | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,419,796 | February 1, 2021 | November 30, 2026 | LEBARON, VIRGINIA TOWNSEND | reporter.nih.gov |
| PATH-Pain: A Primary Care-Based Psychosocial Intervention To Improve Cognitive and Depression Outcomes in Older Adults with MCI and Early Stage AD | NIH | National Institute on Aging | 2021 to 2025 | $3,411,409 | August 15, 2021 | July 31, 2027 | KIOSSES, DIMITRIS N | reporter.nih.gov |
| Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Spine Surgery (MIRHIQL) | NIH | National Institute on Drug Abuse | 2023 | $3,406,550 | August 15, 2023 | July 31, 2026 | HAH, JENNIFER | reporter.nih.gov |
| Prolonged duration and triggered local anesthesia | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,405,757 | May 1, 2019 | May 31, 2029 | KOHANE, DANIEL S | reporter.nih.gov |
| Commercialization of an Improved Treatment of Extremity Fractures Using a Regenerative Bone Adhesive to Accelerate Bone Healing in Aging Patients | NIH | National Institute on Aging | 2023 to 2025 | $3,400,899 | September 30, 2023 | August 31, 2026 | HESS, BRIAN | reporter.nih.gov |
| Psychedelics for Older Adults with Chronic Pain | NIH | National Institute on Aging | 2025 | $3,399,999 | August 15, 2025 | July 31, 2027 | FISCHER, STACY M | reporter.nih.gov |
| Structure and Function of Pentameric Ligand-gated Ion Channels | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,395,619 | January 21, 2020 | December 31, 2029 | CHAKRAPANI, SUDHA | reporter.nih.gov |
| Longitudinal assessment of benefits and harms of cannabis use among community-based cancer patients during initial cancer treatment | NIH | National Cancer Institute | 2023 to 2025 | $3,343,401 | September 19, 2023 | August 31, 2028 | POTOSKY, ARNOLD L | reporter.nih.gov |
| Wake Forest IMPOWR Dissemination Education and Coordination Center (IDEA-CC) | NIH | National Institute on Drug Abuse | 2021 to 2023 | $3,329,368 | September 30, 2021 | July 31, 2027 | ADAMS, MEREDITH C. B. | reporter.nih.gov |
| Mind Body Balance for Pediatric Migraine | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $3,320,406 | June 1, 2020 | May 31, 2026 | POWERS, SCOTT W | reporter.nih.gov |
| Innovative modeling of the biopsychosocial model in animals: Validation of outcomes for assessing emotional and cognitive domains affected by naturally-occurring chronic pain in dogs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $3,320,159 | September 18, 2024 | August 31, 2027 | GRUEN, MARGARET ELIZABETH | reporter.nih.gov |
| Discovery of PSD95 protein-protein interaction inhibitors as novel non-opioid analgesics | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,311,688 | March 1, 2021 | February 28, 2026 | FLORIO, STEPHANIE K | reporter.nih.gov |
| Mechanisms and interventions addressing accelerated cardiovascular disease risk in women with endometriosis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,309,680 | January 5, 2022 | December 31, 2026 | ALEXANDER, LACY M. | reporter.nih.gov |
| Optimizing Response to Chronic Pain Treatments in Veterans: Identifying Key Moderators | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,290,935 | September 15, 2021 | June 30, 2027 | JENSEN, MARK P | reporter.nih.gov |
| Sequential Trial of Adding Buprenorphine, Cognitive Behavioral Treatment, and Transcranial Magnetic Stimulation to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION) | NIH | National Institute on Drug Abuse | 2023 | $3,290,624 | August 15, 2023 | July 31, 2026 | BARTH, KELLY S. | reporter.nih.gov |
| An Efficacy Trial of Community Health Worker-Delivered Chronic Pain Self-Management Support for Vulnerable Older Adults | NIH | National Institute on Aging | 2021 to 2025 | $3,289,340 | September 15, 2021 | August 31, 2026 | JANEVIC, MARY ROSE | reporter.nih.gov |
| Immune modulating therapies to treat complex regional pain syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,283,186 | September 30, 2022 | August 31, 2027 | AJIT, SEENA | reporter.nih.gov |
| A BRIEF, TRANSDIAGNOSTIC COGNITIVE BEHAVIORAL TREATMENT FOR UROLOGIC CHRONIC PELVIC PAIN SYNDROME (UCPPS): PROCESS, PREDICTIONS, OUTCOMES | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,263,376 | September 21, 2021 | July 31, 2027 | LACKNER, JEFFREY M | reporter.nih.gov |
| Biomarkers of Tissue Tolerance and Behavior in a Rat Model | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,262,661 | July 1, 2009 | May 31, 2026 | BARBE, MARY F | reporter.nih.gov |
| Development of Hsp90 Isoform- Selective Inhibitors as a Novel Opioid Dose-Reduction Therapy | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,250,198 | July 15, 2021 | April 30, 2027 | STREICHER, JOHN MICHAEL | reporter.nih.gov |
| A fully-implanted spinal cord stimulation system to restore sensation and relieve phantom limb pain after lower-limb amputation | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,242,520 | September 1, 2025 | August 31, 2027 | FISHER, LEE E | reporter.nih.gov |
| Displacement-guided focused ultrasound for pain modulation. | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $3,220,027 | August 21, 2025 | July 31, 2028 | KONOFAGOU, ELISA E. | reporter.nih.gov |
| Psychometric Reliability and Validity for Behavioral Metrics of Osteoarthritic Pain in Horses | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $3,196,061 | September 19, 2024 | August 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Optimization and multi-site feasibility of yoga for chronic pain in people in treatment for opioid use disorder | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $3,193,009 | April 1, 2020 | March 31, 2026 | UEBELACKER, LISA A | reporter.nih.gov |
| Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes | NIH | National Cancer Institute | 2021 to 2025 | $3,190,411 | April 5, 2021 | March 31, 2027 | SPIEGEL, BRENNAN | reporter.nih.gov |
| \SINGLE ASCENDING DOSE (SAD) PHASE I STUDY | NIH | National Institute on Drug Abuse | 2022 to 2024 | $3,187,404 | July 8, 2016 | June 30, 2026 | BOYLE, CRAIG | reporter.nih.gov |
| Peripherally-restricted non-addictive cannabinoids for cancer pain treatment | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $3,174,343 | August 1, 2023 | July 31, 2025 | SPIGELMAN, IGOR | reporter.nih.gov |
| Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $3,167,756 | September 25, 2019 | July 31, 2025 | SPIEGEL, BRENNAN | reporter.nih.gov |
| Functional peripheral and central vagal neural circuits of interoception inhibiting pain | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $3,162,890 | January 1, 2022 | October 31, 2025 | KIM, YU SHIN | reporter.nih.gov |
| PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,153,647 | July 15, 2021 | April 30, 2027 | NEOGI, TUHINA | reporter.nih.gov |
| Modulation of pain mechanisms by cannabis-derived phytochemicals. | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,150,461 | December 1, 2020 | November 30, 2026 | SETO, TODD B | reporter.nih.gov |
| Physical Activity and Weight Loss to Improve Function and Pain after Total Knee Replacement | NIH | National Institute on Aging | 2021 to 2025 | $3,144,626 | July 15, 2021 | June 30, 2027 | PELLEGRINI, CHRISTINE ANN | reporter.nih.gov |
| Clinical Development of SBS-147: First-in-class Oral Arylepoxamide Agonist for Pain | NIH | National Institute on Drug Abuse | 2025 | $3,138,031 | July 1, 2025 | June 30, 2027 | ASHWORTH, JUDY | reporter.nih.gov |
| Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,129,999 | September 20, 2022 | February 28, 2026 | NWAOKOBIA, CHARLES CHIEDU | reporter.nih.gov |
| Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcoma | NIH | National Cancer Institute | 2025 | $3,128,074 | September 20, 2022 | May 31, 2028 | BRINKMAN, TARA M | reporter.nih.gov |
| Opiod Analgesic Reduction Study (OARS): Managing Acute Post-Operative Surgical Pain | NIH | National Institute of Dental & Craniofacial Research | 2021 | $3,127,499 | August 1, 2020 | July 31, 2024 | FELDMAN, CECILE | reporter.nih.gov |
| University of Michigan BACPAC Mechanistic Research Center | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $3,124,149 | September 26, 2019 | August 31, 2025 | CLAUW, DANIEL J | reporter.nih.gov |
| CNS Mechanisms of IC/BPS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,109,471 | August 1, 2018 | March 31, 2027 | GEREAU, ROBERT W | reporter.nih.gov |
| Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors | NIH | National Cancer Institute | 2023 to 2025 | $3,108,577 | September 20, 2022 | August 31, 2027 | IM, EUN-OK | reporter.nih.gov |
| Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $3,098,703 | August 12, 2022 | June 30, 2027 | KWOH, C KENT | reporter.nih.gov |
| Analgesic and subjective effects of terpenes administered alone and in combination with THC: Potential THC- and opioid-sparing effects of myrcene and ß-caryophyllene | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,089,484 | February 15, 2020 | January 31, 2026 | COOPER, ZIVA D | reporter.nih.gov |
| Quantifying and Treating Myofascial Dysfunction in Post Stroke Shoulder Pain | NIH | National Center for Complementary & Integrative Health | 2024 | $3,086,679 | September 21, 2022 | August 31, 2027 | RAGHAVAN, PREETI | reporter.nih.gov |
| Genetic and chemical biological studies of K2P structure, function, andmodulation | NIH | National Institute of Mental Health | 2022 to 2025 | $3,080,529 | March 1, 2011 | February 28, 2027 | MINOR, DANIEL L | reporter.nih.gov |
| Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $3,077,376 | September 17, 2024 | August 31, 2027 | HELLMAN, KEVIN | reporter.nih.gov |
| Anti-inflammatory Cell Based Repair of Intervertebral Disc Degeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,075,117 | September 1, 2021 | August 31, 2026 | CHAHINE, NADEEN O. | reporter.nih.gov |
| TRPV1 nociceptors in oral carcinogenesis and pain | NIH | National Cancer Institute | 2021 to 2025 | $3,070,266 | March 1, 2021 | February 28, 2027 | ALBERTSON, DONNA G | reporter.nih.gov |
| The glymphatic system at the crossroad of integrative health approaches inchronic pain | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,067,927 | August 1, 2021 | May 31, 2026 | NEDERGAARD, MAIKEN | reporter.nih.gov |
| Cannabis use among older adults: Potential risks and benefits to an aging population | NIH | National Institute on Aging | 2021 to 2025 | $3,055,285 | February 15, 2021 | January 31, 2027 | BRYAN, ANGELA | reporter.nih.gov |
| Accelerating the non-opioid analgesic AFA-281 clinical development with TABA-supported business development | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,049,862 | August 1, 2025 | April 30, 2026 | XIE, XINMIN SIMON | reporter.nih.gov |
| Maladaptive Plasticity in Spinal Cord Injury: Cellular Mechanisms | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,042,505 | July 15, 2021 | June 30, 2026 | FERGUSON, ADAM R | reporter.nih.gov |
| The PREVENTABLE Physical Performance Ancillary Study | NIH | National Institute on Aging | 2021 to 2024 | $3,040,350 | September 30, 2021 | May 31, 2028 | HOUSTON, DENISE KATHRYN | reporter.nih.gov |
| Development of a Novel Chemokine Receptor Antagonist Peptide as a Non-Opioid Treatment for Relief of Chronic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,999,505 | September 15, 2021 | August 31, 2023 | RUFF, MICHAEL R | reporter.nih.gov |
| Nociceptive Mechanisms Underlying Sickle Cell Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,998,866 | September 30, 2009 | December 31, 2028 | STUCKY, CHERYL LOUISE | reporter.nih.gov |
| Designing Novel MR Imaging Tools to Quantify Lower-Limb Exercise Adaptations in Knee Osteoarthritis | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2025 | $2,997,092 | September 20, 2003 | April 30, 2028 | GOLD, GARRY E | reporter.nih.gov |
| Electrical stimulation to reduce pain and improve function after knee replacement | NIH | National Institute on Aging | 2021 to 2023 | $2,996,575 | August 15, 2015 | August 31, 2025 | BOGGS, JOSEPH WILDER | reporter.nih.gov |
| Signal integration by specialized mesenchyme in urothelial homeostasis and Interstitial Cystitis / Bladder Pain Syndrome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,991,425 | September 24, 2022 | August 31, 2027 | BEACHY, PHILIP A | reporter.nih.gov |
| Genetically-engineered stem cells for self-regulating arthritis therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,983,611 | April 1, 2022 | March 31, 2027 | GUILAK, FARSHID | reporter.nih.gov |
| Transcending COVID-19 barriers to pain care in rural America: Pragmatic comparative effectiveness trial of evidence-based, on-demand, digital behavioral treatments for chronic pain | NIH | National Institute of Nursing Research | 2021 to 2023 | $2,982,292 | June 10, 2021 | September 30, 2025 | SPIEGEL, BRENNAN | reporter.nih.gov |
| Comprehensive Phenotyping of Specific Populations of Spinal Neurons Processing Cutaneous Information Before and After Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,973,851 | September 16, 2016 | August 31, 2026 | KOERBER, H RICHARD | reporter.nih.gov |
| Development of KLS-13019 for Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,970,772 | September 30, 2021 | August 31, 2025 | BRENNEMAN, DOUGLAS ERIC | reporter.nih.gov |
| Individual differences in brain morphology and connectivity to identify the mechanisms of comorbidities and treatment-refractory disease in females with endometriosis-associated pelvic pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $2,969,745 | August 1, 2025 | July 31, 2028 | SCHREPF, ANDREW | reporter.nih.gov |
| Dissection of SARM1-Induced Axon Degeneration and Cell Death | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,966,646 | September 1, 2014 | May 31, 2029 | MILBRANDT, JEFFREY D | reporter.nih.gov |
| A staged, comprehensive investigation for developing insular deep brain stimulation to treat refractory chronic pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,959,839 | September 20, 2022 | December 31, 2028 | ELIAS, WILLIAM JEFFREY | reporter.nih.gov |
| Optimizing the value of pain management in knee OA patients with comorbidities | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,947,711 | August 1, 2018 | March 31, 2029 | LOSINA, ELENA | reporter.nih.gov |
| Developing Active Stimulation and Monitoring Technologies to Optimize Pain and Nociception Management During Regional Anesthesia, General Anesthesia, and Post-Operative Care | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,938,451 | September 19, 2023 | August 31, 2026 | LE MAU, TUAN | reporter.nih.gov |
| Knee Arthroplasty Activity Trial (KArAT) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,935,459 | September 23, 2022 | August 31, 2027 | LOSINA, ELENA | reporter.nih.gov |
| Tear protein biomarkers of refractive surgery pain | NIH | National Eye Institute | 2023 to 2025 | $2,933,372 | September 1, 2020 | February 28, 2027 | AICHER, SUE A | reporter.nih.gov |
| Indiana University (IU) Clinical Center for Chronic Pancreatitis Clinical Research Network | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,908,091 | September 28, 2015 | June 30, 2030 | EASLER, JEFFREY JAMES | reporter.nih.gov |
| Allosteric Targeting of Cannabinoid CB1 Receptor to Develop Non-Addictive Small Molecule Analgesics | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,903,097 | September 1, 2022 | August 31, 2025 | LU, DAI | reporter.nih.gov |
| Mechanism and optimization of CBD-mediated analgesic effects (Diversity Supplement) | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,902,023 | September 15, 2019 | June 30, 2025 | HE, ZHIGANG | reporter.nih.gov |
| Molecular Pathways of Pain Generation in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,896,087 | February 1, 2011 | June 30, 2026 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Effects of Sleep Disruption on Subjective Responses to Opioid Administration in Patients with Chronic Pain | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,894,566 | May 1, 2019 | February 28, 2026 | SMITH, MICHAEL T | reporter.nih.gov |
| Intratumor co-delivery of DNA and RNA to relieve cancer pain | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,893,104 | January 8, 2021 | December 31, 2026 | SCHMIDT, BRIAN L | reporter.nih.gov |
| CMG2 as a target for safe and effective treatment of endometriosis-associate pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,887,122 | September 20, 2022 | August 31, 2027 | ROGERS, MICHAEL SEAN | reporter.nih.gov |
| P-QST Project: Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,884,008 | July 1, 2021 | June 30, 2027 | PHILLIPS, ANNA EVANS | reporter.nih.gov |
| Investigating Mechanisms of Intra- and Inter-individual Pain Variability in Patients with Comorbid Chronic Pain and Depression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $2,884,008 | May 29, 2025 | April 30, 2028 | HERBERT, MATTHEW S | reporter.nih.gov |
| Optimization of Cannabinoids for Development as FDA-Approved Migraine Therapeutics | NIH | National Institute on Drug Abuse | 2024 to 2025 | $2,883,639 | September 30, 2020 | August 31, 2026 | PAPPAS, GEORGE | reporter.nih.gov |
| Characterization of the Properties and Mechanisms of Photobiomodulation-Induced Axonal Block and Evaluation as a Treatment for Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,878,214 | May 1, 2021 | April 30, 2027 | MOFFITT, MICHAEL | reporter.nih.gov |
| Identifying novel therapeutic targets for chronic neck pain: RNA-sequencing in human painful atlanto-axial arthropathy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,872,749 | September 1, 2021 | August 31, 2026 | CURATOLO, MICHELE | reporter.nih.gov |
| Cannabinoid interactions with central and peripheral pain mechanisms in osteoarthritis of the knee | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $2,864,374 | August 1, 2020 | May 31, 2026 | HARTE, STEVEN EDWARD | reporter.nih.gov |
| Quantitative Multiparametric MRI to Assess the Effect of Stem Cell Therapy on Chronic Low Back Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,858,064 | August 1, 2014 | July 31, 2025 | LI, DEBIAO | reporter.nih.gov |
| Deterrents for prescription opioid abuse | NIH | National Institute on Drug Abuse | 2021 to 2025 | $2,853,877 | September 15, 2015 | May 31, 2027 | FREEMAN, KEVIN B. | reporter.nih.gov |
| Opioid and cannabinoid interactions in pain and reward | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,852,096 | September 30, 2020 | June 30, 2026 | NEUBERT, JOHN K | reporter.nih.gov |
| Voltage-Gated Calcium Channels in Nociceptors and Mechanoreceptors | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,837,880 | August 2, 2006 | July 31, 2027 | LIPSCOMBE, DIANE | reporter.nih.gov |
| Targeting Schwann cell dysfunction and repair signaling in chemotherapy induced painful peripheral neuropathy | NIH | National Institute of Dental & Craniofacial Research | 2024 | $2,833,086 | September 20, 2024 | August 31, 2027 | YE, YI | reporter.nih.gov |
| Glycosaminoglycans to Treat and Prevent Radiation-Induced Oral Mucositis | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2023 | $2,826,053 | September 20, 2021 | February 28, 2025 | SAVAGE, JUSTIN RODNEY | reporter.nih.gov |
| Discovery and development of potent inhibitors of Jun N-terminal kinase for non-hormonal treatment of endometriosis and associated pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,824,721 | August 11, 2021 | May 31, 2026 | MONSIVAIS, DIANA | reporter.nih.gov |
| Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,821,209 | September 10, 2021 | August 31, 2026 | BUXBAUM, LAUREL J | reporter.nih.gov |
| Cannabis use and outcomes in ambulatory patients with cancer: A 12-month cohort study | NIH | National Cancer Institute | 2022 to 2025 | $2,815,567 | April 15, 2022 | March 31, 2027 | MEGHANI, SALIMAH H. | reporter.nih.gov |
| Improving pain management and opioid safety through a systemwide, data driven evaluation of the CDC opioid prescribing guideline best practices and the use of Clinical Decision Support | NIH | National Institute on Drug Abuse | 2024 | $2,814,796 | September 30, 2022 | August 31, 2027 | HOPPE, JASON | reporter.nih.gov |
| Metabolomic Signatures of Urologic Chronic Pelvic Pain Syndrome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,812,460 | July 15, 2021 | April 30, 2027 | HENDERSON, JEFFREY P | reporter.nih.gov |
| Long-term Suppressive Valacyclovir Treatment for Herpes Zoster Ophthalmicus | NIH | National Eye Institute | 2022 to 2023 | $2,806,822 | September 30, 2016 | July 31, 2023 | COHEN, ELISABETH J | reporter.nih.gov |
| Improving Physical and Psychosocial Functioning in Older Adults: A Community Health Worker-Led Intervention | NIH | National Institute of Nursing Research | 2021 to 2025 | $2,796,614 | September 24, 2021 | June 30, 2027 | JANEVIC, MARY ROSE | reporter.nih.gov |
| Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms | NIH | National Institute on Drug Abuse | 2021 to 2025 | $2,790,999 | May 1, 2021 | February 28, 2027 | BRUEHL, STEPHEN | reporter.nih.gov |
| Adapting Web-based CBT to improve adherence and outcome for individuals with opioid use disorder and chronic pain treated with opioid agonists | NIH | National Center for Complementary & Integrative Health | 2022 to 2024 | $2,785,965 | June 1, 2022 | February 28, 2026 | HEAPY, ALICIA | reporter.nih.gov |
| Simultaneous Imaging of Tissue Biochemistry and Metabolism associated with Biomechanics in Patella Femoral Joint Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,778,600 | March 15, 2022 | February 28, 2027 | SOUZA, RICHARD BRIAN | reporter.nih.gov |
| Selective actin remodeling of sensory neurons for acute pain management | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,776,138 | September 19, 2023 | August 31, 2025 | BLUM, PAUL | reporter.nih.gov |
| Weighting Longitudinal Data to Access Opioid Analgesia Tapering Outcomes among Patients with Co-occurring Chronic Pain and Substance Use Disorder | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,773,978 | September 30, 2022 | July 31, 2027 | QEADAN, FARES | reporter.nih.gov |
| Modulation of local adenosine signaling to attenuate fracture pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,768,294 | April 15, 2021 | March 31, 2027 | VARGHESE, SHYNI | reporter.nih.gov |
| Mechanisms of Pain Associated with Trigeminal Nerve Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,760,934 | August 1, 2021 | June 30, 2027 | GOLD, MICHAEL S | reporter.nih.gov |
| Interdisciplinary Research Training in Pain and/or Substance Use Disorders | NIH | National Institute on Drug Abuse | 2021 to 2025 | $2,755,818 | July 1, 2013 | June 30, 2029 | MACKEY, SEAN C | reporter.nih.gov |
| Linking VA and non-VA data to study the risk of suicide in chronic pain patients. | NIH | National Institute of Mental Health | 2021 to 2024 | $2,750,827 | August 10, 2020 | May 31, 2025 | PATHAK, JYOTISHMAN | reporter.nih.gov |
| Real-Time and Long-Term Effects of Medical Marijuana on Older Adults: A Prospective Cohort Study | NIH | National Institute on Aging | 2022 to 2025 | $2,747,244 | February 15, 2022 | November 30, 2026 | WANG, YAN | reporter.nih.gov |
| Next Generation Gene Therapy for Refractory Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,745,930 | February 1, 2022 | January 31, 2027 | RENTHAL, WILLIAM RUSSELL | reporter.nih.gov |
| Individualized Assessment and Treatment Program for TMD: Coping as a Mechanism | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $2,740,343 | February 11, 2020 | June 30, 2024 | LITT, MARK D. | reporter.nih.gov |
| The Physiology of Store-Operated Channels in the Nervous System | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,728,667 | May 1, 2023 | April 30, 2031 | PRAKRIYA, MURALI | reporter.nih.gov |
| Validation of Prenatal Rabbit Hypoxia Ischemia as a Model of Cerebral Palsy-induced Pain | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,727,001 | September 19, 2023 | August 31, 2026 | QUINLAN, KATHARINA ANN | reporter.nih.gov |
| Mechanisms of cannabidiol in persons with MS: the role of sleep and pain phenotype | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $2,725,289 | August 15, 2021 | May 31, 2026 | BRALEY, TIFFANY JOY | reporter.nih.gov |
| Neutralizing the degenerate disc microenvironment to enhance the efficacy of therapeutic stem cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,717,504 | February 1, 2021 | December 31, 2026 | SMITH, LACHLAN JAMES | reporter.nih.gov |
| Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging | NIH | National Cancer Institute | 2025 | $2,714,830 | August 6, 2025 | July 31, 2030 | ZHENG, QIN | reporter.nih.gov |
| Administrative Supplement: Medical Marijuana, Pain, and Opioid Use in Patients with Chronic Non-cancer Pain | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,712,570 | September 30, 2021 | June 30, 2026 | GILMAN, JODI | reporter.nih.gov |
| Central glutamate signaling in postoperative pain regulation - Renewal 2 | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,705,425 | August 1, 2015 | July 31, 2028 | WANG, JING | reporter.nih.gov |
| Mechanisms of alteration of gastrointestinal physiology by gut microbes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,700,677 | September 1, 2017 | June 30, 2027 | KASHYAP, PURNA C | reporter.nih.gov |
| Identifying plasma proteomic profiles of chronic pain development in endometriosis from adolescence to adulthood | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 | $2,689,739 | September 19, 2023 | August 31, 2026 | SASAMOTO, NAOKO | reporter.nih.gov |
| Enhancing Exercise and Psychotherapy to Treat Comorbid Addiction and Pain for ImprovingAdherence to Medication Assisted Treatment in Opioid Use Disorders | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $2,684,192 | September 28, 2019 | November 30, 2025 | NOCK, NORA L. | reporter.nih.gov |
| Study of Activity-Dependent Sympathetic Sprouting | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,675,718 | May 4, 2004 | June 30, 2026 | ZHANG, JUN-MING | reporter.nih.gov |
| Role of Developmental Signaling Pathways in Maintenance of Spinal Discs | NIH | National Institute on Aging | 2021 to 2024 | $2,674,109 | August 15, 2021 | April 30, 2027 | DAHIA, CHITRA L | reporter.nih.gov |
| Randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,669,702 | April 11, 2022 | March 31, 2027 | PALERMO, TONYA M | reporter.nih.gov |
| Implantable, Degradable Drug Delivery Devices for Non-Opioid Post-Surgical Pain Management | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $2,668,301 | September 15, 2025 | August 31, 2028 | BURKE, KELLY ANNE | reporter.nih.gov |
| Rehabilitation from Spinal Cord Injury Using Targeted, Activity-Dependent Intraspinal Stimulation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,662,265 | August 15, 2021 | July 31, 2026 | PERLMUTTER, STEVE I | reporter.nih.gov |
| Pain Sensitivity and Unpleasantness in People with Alzheimer's Disease and Cancer | NIH | National Institute on Aging | 2021 to 2023 | $2,659,054 | August 15, 2019 | May 31, 2026 | COWAN, RONALD L | reporter.nih.gov |
| Mindfulness meditation training for Irritable Bowel Syndrome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,643,486 | May 4, 2021 | April 30, 2026 | CRESWELL, JOHN DAVID | reporter.nih.gov |
| Trajectories of non-pharmacologic and opioid health services for pain management in association with military readiness and health status outcomes: SUPIC renewal | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,634,655 | September 1, 2014 | July 31, 2025 | LARSON, MARY JO | reporter.nih.gov |
| Molecular mechanism and targeting of chronic pain in sickle cell disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,632,365 | January 16, 2018 | January 31, 2025 | WANG, ZAIJIE JIM | reporter.nih.gov |
| Neuro-immune modulation of pain in health and disease | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,624,155 | September 1, 2022 | August 31, 2027 | DONNELLY, CHRISTOPHER RYAN | reporter.nih.gov |
| Pharmacogenomics to Catalyze Decision Support in Oncology Care | NIH | National Human Genome Research Institute | 2023 to 2025 | $2,619,474 | June 1, 2023 | March 31, 2028 | O'DONNELL, PETER HUGH | reporter.nih.gov |
| Development of a novel disease-modifying glycan therapeutic for early at-home intervention of acute vaso-occlusive crisis in sickle cell disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $2,611,866 | March 5, 2023 | February 28, 2026 | JOHN PADERI, JOHN PADERI JOHN PADERI | reporter.nih.gov |
| CAPSITE: Community Assessment of Pain and Sensitization in the Elderly | NIH | National Institute on Aging | 2021 to 2025 | $2,604,210 | January 1, 2020 | November 30, 2026 | NEOGI, TUHINA | reporter.nih.gov |
| Supraspinal Processing of Sensory Aspects of Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,602,000 | December 22, 2000 | August 31, 2027 | COGHILL, ROBERT C | reporter.nih.gov |
| Neurobiological and psychosocial risk for transition from acute to chronic musculoskeletal pain in adolescence | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,599,410 | August 5, 2022 | July 31, 2027 | WILSON, ANNA CAMILLE | reporter.nih.gov |
| Harvard School of Dental Medicine Collaborative Clinical Practice-based REsearch Program for DENTal Schools (H-CREDENT) | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,593,801 | September 13, 2023 | June 30, 2028 | GIANNOBILE, WILLIAM V | reporter.nih.gov |
| Anatomic, Physiologic and Transcriptomic Mechanisms of Neuropathic Pain in Human DRG | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,590,497 | April 15, 2020 | February 28, 2026 | DOUGHERTY, PATRICK M | reporter.nih.gov |
| A novel glycan-based selectin and complement inhibitor for at-home disease-modifying rescue of pain crisis in sickle cell disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,589,070 | September 18, 2023 | August 31, 2025 | JOHN PADERI, JOHN PADERI JOHN PADERI | reporter.nih.gov |
| NeuronS_MATTR Network: Neuronal & Systems Mechanisms of Affective Touch & Therapeutic Tissue Manipulation Research Network | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $2,583,267 | April 20, 2022 | March 31, 2027 | LUMPKIN, ELLEN A | reporter.nih.gov |
| Development of an Opioid Sparing Therapeutic to Minimize Opioid Use Disorderand Tolerance in the Treatment of Pain | NIH | National Institute on Drug Abuse | 2023 | $2,579,875 | September 1, 2023 | August 31, 2025 | MEYN, MALCOLM A | reporter.nih.gov |
| TRPV1-dependent neuro-immune modulation and regulation of endogenous acyl-dopamines in sepsis and acute inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,579,514 | June 3, 2022 | May 31, 2027 | HELLMAN, JUDITH | reporter.nih.gov |
| Role of TNFalpha in discogenic pain progression and as a treatment target | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,577,911 | February 1, 2022 | December 31, 2026 | IATRIDIS, JAMES C. | reporter.nih.gov |
| Neural Mechanisms of Immersive Virtual Reality in Chronic Pain | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $2,576,515 | August 1, 2021 | May 31, 2027 | COLLOCA, LUANA | reporter.nih.gov |
| SPINE-WORK: An inclusive research community to study and improve force-based manipulations for spine pain | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $2,571,690 | April 20, 2022 | March 31, 2027 | WINKELSTEIN, BETH A | reporter.nih.gov |
| Targeting checkpoint inhibitors for pain control | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,569,851 | September 21, 2023 | August 31, 2026 | JI, RU-RONG | reporter.nih.gov |
| Multi-Omic Biomarkers for Neuropathic Pain Secondary to Chemotherapy | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $2,568,308 | September 30, 2020 | August 31, 2025 | ROTROFF, DANIEL | reporter.nih.gov |
| The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,563,053 | August 1, 2020 | July 31, 2025 | HUARD, JOHNNY | reporter.nih.gov |
| Best Case/Worst Case: A Multisite Randomized Clinical Trial of Scenario Planning for Patients with End-Stage Kidney Disease | NIH | National Institute on Aging | 2021 to 2024 | $2,560,965 | June 1, 2020 | February 28, 2026 | SCHWARZE, MARGARET | reporter.nih.gov |
| Mechanisms for Regenerative Healing in Intervertebral Discs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,560,545 | January 15, 2022 | December 31, 2026 | IATRIDIS, JAMES C. | reporter.nih.gov |
| Evaluating Standing as a Health Behavior to Promote Cardiovascular Risk Reduction in African Americans | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,554,747 | April 15, 2021 | March 31, 2026 | DIAZ, KEITH M | reporter.nih.gov |
| Understanding Mechanisms and Sex-Differences in Visceral Pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,551,050 | September 1, 2023 | May 31, 2028 | INGRAHAM, HOLLY A. | reporter.nih.gov |
| Evaluation of Small-Fiber Polyneuropathy in Youth | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,545,391 | August 15, 2015 | May 31, 2026 | OAKLANDER, ANNE LOUISE | reporter.nih.gov |
| Chemical biology of Peptide Regulation of Opioid Receptor Function | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,544,923 | May 1, 2020 | February 28, 2026 | HASKELL-LUEVANO, CARRIE | reporter.nih.gov |
| Role of disability and pain in opioid overdose: mechanism and risk mitigation | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,540,888 | March 1, 2022 | January 31, 2027 | RUDOLPH, KARA ELIZABETH | reporter.nih.gov |
| Pain in community-based older African American Adults: The Jackson Heart Study | NIH | National Institute on Aging | 2021 to 2024 | $2,538,438 | September 30, 2020 | May 31, 2026 | NEOGI, TUHINA | reporter.nih.gov |
| Effects of Fish Oil ± Salsalate on the Omega-3 Index and the Circulating Lipodome of Omega-3 Polyunsaturated Fatty Acid Metabolites in Patients with Type 2 Diabetes and Diabetic Neuropathy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,534,893 | February 7, 2022 | January 31, 2027 | YOREK, MARK A. | reporter.nih.gov |
| Using Mouse Pain Scales to Discover Unusual Pain Sensitivity and New Pain Targets | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $2,530,010 | July 1, 2023 | June 30, 2024 | ABDUS-SABOOR, ISHMAIL JOHN | reporter.nih.gov |
| Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty | NIH | National Institute on Aging | 2025 | $2,526,074 | September 30, 2023 | August 31, 2028 | BRUEHL, STEPHEN | reporter.nih.gov |
| REmotely-delivered Supportive Programs for Improving surgical pain and disTrEss (RESPITE) | NIH | National Cancer Institute | 2022 to 2025 | $2,524,281 | August 7, 2022 | July 31, 2027 | SOHL, STEPHANIE JEAN | reporter.nih.gov |
| Online TEAM Migraine: Online Techniques and Education Aimed to Manage Migraine | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $2,523,202 | July 1, 2022 | June 30, 2027 | WELLS, REBECCA ERWIN | reporter.nih.gov |
| Biopsychosocial pain predictors of mobility decline in aging | NIH | National Institute on Aging | 2022 to 2025 | $2,519,850 | June 1, 2022 | February 28, 2027 | CRUZ-ALMEIDA, YENISEL | reporter.nih.gov |
| Scale up single-cell technologies to map pain-associated genes and cells across the lifespan | NIH | National Center for Advancing Translational Sciences | 2022 | $2,518,511 | September 15, 2022 | August 31, 2025 | SHU, JIAN | reporter.nih.gov |
| Understanding the role of early life social determinants and sex-specific pubertal pathways in the development of adolescent chronic pain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $2,515,828 | September 30, 2025 | August 31, 2029 | LI, RUI | reporter.nih.gov |
| Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial | NIH | National Cancer Institute | 2022 to 2025 | $2,513,680 | June 1, 2022 | May 31, 2027 | RINI, CHRISTINE | reporter.nih.gov |
| Structure, function, and pharmacology of neuronal membrane transport proteins | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,513,041 | September 1, 2016 | August 31, 2024 | LEE, SEOK-YONG | reporter.nih.gov |
| Genetic and Environmental Origins of the Development of Pain in Children | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,512,240 | August 1, 2016 | February 28, 2027 | DAVIS, MARY COLLEEN | reporter.nih.gov |
| Total-body PET for assessing myofascial pain | NIH | National Center for Complementary & Integrative Health | 2025 | $2,507,539 | September 19, 2022 | August 31, 2027 | CHAUDHARI, ABHIJIT J | reporter.nih.gov |
| A Superiority Trial of Radiofrequency Ablation for Low Back Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $2,502,935 | September 4, 2024 | August 31, 2029 | SURI, PRADEEP | reporter.nih.gov |
| Neural and Energetic Drivers of Performance and Perceived Fatigability in Older Adults | NIH | National Institute on Aging | 2022 to 2025 | $2,501,429 | September 15, 2022 | May 31, 2027 | ROSANO, CATERINA | reporter.nih.gov |
| A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III) | NIH | National Institute on Aging | 2024 to 2025 | $2,500,587 | September 15, 2024 | August 31, 2029 | FANNING, JASON | reporter.nih.gov |
| Development of an oral analgesic with reduced liabilities | NIH | National Institute on Drug Abuse | 2022 to 2023 | $2,500,000 | April 15, 2022 | March 31, 2025 | GEHLERT, DONALD R | reporter.nih.gov |
| New Inactivators of GABA Aminotransferase for Epilepsy and Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,498,237 | July 15, 2021 | June 30, 2026 | SILVERMAN, RICHARD B | reporter.nih.gov |
| Emotion regulation as a primary mechanism of action in yoga interventions for chronic low back pain: An RCT testing biological and psychological pathways | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $2,498,080 | June 1, 2020 | May 31, 2026 | PARK, CRYSTAL L. | reporter.nih.gov |
| Genotype-Phenotype Relationships in Fragile X Families | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,496,604 | June 15, 1998 | May 31, 2028 | HAGERMAN, RANDI J. | reporter.nih.gov |
| Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive Enzyme | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,493,979 | April 1, 2022 | March 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Engaging Veterans Seeking Service-Connection Payments in Pain Treatment | NIH | National Center for Complementary & Integrative Health | 2022 to 2023 | $2,493,751 | September 20, 2017 | August 31, 2025 | ROSEN, MARC I | reporter.nih.gov |
| Ultra-High-Throughput Plate Reader for Drug Discovery Using All-Optical Electrophysiology | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,492,936 | February 17, 2025 | August 31, 2025 | LU, YANG | reporter.nih.gov |
| Development of anti-inflammatory nanodrug for endometriosis treatment | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,492,373 | September 30, 2022 | June 30, 2027 | KIM, TAEHO | reporter.nih.gov |
| Brain Circuits of Migraine Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,478,945 | September 30, 2022 | July 31, 2027 | PORRECA, FRANK | reporter.nih.gov |
| A Mobile Health Behavioral Pain Intervention Protocol for Breast Cancer Patients with Pain in Medically Underserved Communities: A Randomized Controlled Trial | NIH | National Cancer Institute | 2021 to 2024 | $2,478,031 | January 10, 2020 | December 31, 2025 | SOMERS, TAMARA J | reporter.nih.gov |
| Ion Channel Pharmacology for Pain and Epilepsy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,475,651 | May 1, 2022 | April 30, 2025 | BEAN, BRUCE P | reporter.nih.gov |
| Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis | NIH | National Cancer Institute | 2021 to 2024 | $2,474,212 | April 1, 2020 | March 31, 2026 | SHELBY, REBECCA A | reporter.nih.gov |
| Improving Function and Reducing Opioid Use for Patients with Chronic Low Back Pain in Rural Communities through Improved Access to Physical Therapy using Telerehabilitation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $2,471,042 | September 25, 2023 | July 31, 2028 | SKOLASKY, RICHARD L. | reporter.nih.gov |
| IND-enabling toxicology studies to reach IND approval for a proprietary biologic to treat oral mucositis in cancer patients | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2024 | $2,470,033 | September 21, 2023 | August 31, 2025 | YOUNG, CHRISTIAN | reporter.nih.gov |
| Amygdala pain mechanisms | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,469,334 | December 15, 2021 | November 30, 2026 | NEUGEBAUER, VOLKER | reporter.nih.gov |
| Novel Approaches to Opiate Use Reduction | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,469,078 | April 1, 2020 | January 31, 2026 | HUTCHISON, KENT E. | reporter.nih.gov |
| “Conus venom peptides and their molecular targets: Using pharmaconomics and neuroethology as a framework for discovery” | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,461,992 | March 15, 2022 | February 28, 2026 | OLIVERA, BALDOMERO M | reporter.nih.gov |
| Efficient and Cost-Effective Multimodal System for Pain Management in Low Back Pain | NIH | National Institute of Nursing Research | 2021 to 2025 | $2,459,788 | March 16, 2020 | December 31, 2026 | HAMMAL, ZAKIA | reporter.nih.gov |
| Altered T Cell Responses in Myalgic Enchephalomeylitis/Chronic Fatigue Syndrome (ME/CFS) | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,446,878 | March 8, 2021 | February 28, 2027 | SELIN, LIISA KAARINA | reporter.nih.gov |
| Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain with Machine Learning to Predict Treatment Response | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,446,704 | August 1, 2015 | March 31, 2027 | FREGNI, FELIPE | reporter.nih.gov |
| Patterns and predictors of symptoms, falls, and functioning across treatment and recovery in patients treated with neurotoxic chemotherapy for cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,446,165 | September 10, 2020 | June 30, 2026 | WINTERS-STONE, KERRI M | reporter.nih.gov |
| Regulation of Opioid Sensitivity and Tolerance by Ubiquitin Ligase Signaling | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,445,633 | July 15, 2022 | May 31, 2027 | GRILL, BROCK | reporter.nih.gov |
| Imaging neuroglial mechanisms of neuropathic pain-opioid interaction in HIV | NIH | National Institute on Drug Abuse | 2021 to 2022 | $2,441,399 | July 15, 2018 | July 31, 2025 | LOGGIA, MARCO LUCIANO | reporter.nih.gov |
| Neuropeptidergic Inhibition of Spinal Pain Transmission | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,433,566 | September 10, 2002 | November 30, 2026 | TAYLOR, BRADLEY K. | reporter.nih.gov |
| Control of Seizure and Migraine Susceptibility by GPR37L1 | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,433,005 | July 15, 2021 | June 30, 2027 | HALL, RANDY A. | reporter.nih.gov |
| Novel biomarkers and pathways of persistent endometriosis-associated pain across the life course | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,430,576 | March 23, 2023 | February 29, 2028 | AS-SANIE, SAWSAN | reporter.nih.gov |
| The cellular and molecular mechanisms underlying nociception and pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,430,000 | September 15, 2021 | August 31, 2026 | SHARMA, NIKHIL | reporter.nih.gov |
| Rapid Quantitative Assessment of Knee Joint with Compressed Sensing | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,428,622 | August 3, 2020 | July 31, 2026 | REGATTE, RAVINDER | reporter.nih.gov |
| Development and identification of magnetic resonance, electrophysiological, and fiber-optic imaging biomarkers of myofascial pain | NIH | National Center for Complementary & Integrative Health | 2025 | $2,426,607 | September 20, 2022 | August 31, 2027 | HU, SONG | reporter.nih.gov |
| Androgen Replacement to Improve Patient-Important Outcomes in Men with Opioid-Induced Hypogonadism | NIH | National Institute on Aging | 2021 to 2023 | $2,425,607 | September 30, 2020 | May 31, 2027 | BASARIA, SHEHZAD | reporter.nih.gov |
| Genipin’s ECM Crosslinking Action as an Agent to Prevent Neurodegeneration in Familial Dysautonomia | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,424,350 | April 1, 2021 | June 30, 2030 | ZELTNER, NADJA | reporter.nih.gov |
| Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,420,406 | August 15, 2020 | July 31, 2025 | GRAHN, PETER JONAS | reporter.nih.gov |
| Immunomodulatory Therapy for Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,420,195 | September 1, 2018 | August 31, 2025 | CHEN, RIDONG | reporter.nih.gov |
| Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in vivo) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,419,698 | September 30, 2015 | November 30, 2026 | DASILVA, ALEXANDRE | reporter.nih.gov |
| The Pain Identification and Communication Toolkit: A Training Program to Support Family Caregivers of Persons with ADRD | NIH | National Institute on Aging | 2023 to 2025 | $2,413,080 | February 15, 2023 | January 31, 2028 | RIFFIN, CATHERINE | reporter.nih.gov |
| Enhancing Efficacy of Migraine Self-Management in Children with Comorbid Insomnia | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,410,913 | April 14, 2020 | March 31, 2026 | PALERMO, TONYA M | reporter.nih.gov |
| Development of Pathology-activated Drugs for Treatment of Neuropathic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,408,109 | September 20, 2022 | August 31, 2024 | GRACE, PETER M | reporter.nih.gov |
| The Effects of Visit Characteristics on Patient-Clinician Interactions and Health Outcomes in Knee Osteoarthritis | NIH | National Institute on Aging | 2023 to 2025 | $2,402,726 | September 1, 2023 | June 30, 2028 | DOSSETT, MICHELLE L | reporter.nih.gov |
| A Stress and Pain Self-management m-Health App for Adult Outpatients with Sickle Cell Disease | NIH | National Institute of Nursing Research | 2021 to 2024 | $2,402,223 | September 7, 2020 | June 30, 2026 | EZENWA, MIRIAM OMELEBELE | reporter.nih.gov |
| Next generation anti-cancer drugdelivering cement for bone metastasis patients | NIH | National Cancer Institute | 2022 to 2025 | $2,399,999 | September 1, 2022 | August 31, 2027 | JANG, HAE LIN | reporter.nih.gov |
| A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury (SCI) | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,395,166 | September 15, 2020 | April 30, 2027 | LAD, SHIVANAND P | reporter.nih.gov |
| VZV in the enteric nervous system: pathogenesis and consequences | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,394,880 | August 1, 2011 | June 30, 2027 | GERSHON, ANNE A. | reporter.nih.gov |
| Disruption of Homeostatic Neuroimmune Interactions in Descending Circuitry in the Development of Pain Chronicity | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $2,391,373 | July 1, 2020 | June 30, 2026 | WEI, FENG | reporter.nih.gov |
| Supporting Family Caregivers of Persons with Dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,389,895 | January 15, 2022 | December 31, 2026 | DEMIRIS, GEORGE | reporter.nih.gov |
| Bionic Breast Project: A Neuroprosthesis to Restore Touch Sensation and Reduce Chronic Pain After Mastectomy | NIH | National Cancer Institute | 2023 to 2025 | $2,385,909 | August 1, 2023 | July 31, 2028 | LINDAU, STACY TESSLER | reporter.nih.gov |
| Multi-organ-on-chip device for modeling opioid reinforcement and withdrawal, and the negative affective component of pain: a therapeutic screening tool. | NIH | National Center for Advancing Translational Sciences | 2022 to 2024 | $2,380,820 | September 26, 2019 | July 31, 2025 | MAIDMENT, NIGEL T | reporter.nih.gov |
| Advancing Clinical Science in Pediatric Gastroparesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,376,063 | September 25, 2016 | July 31, 2027 | PREIDIS, GEOFFREY A | reporter.nih.gov |
| Identification and validation of LPA/LPAR signaling as a target for the treatment of temporomandibular disorder pain | NIH | National Institute of Dental & Craniofacial Research | 2024 | $2,372,116 | July 5, 2024 | June 30, 2027 | CHEN, YONG | reporter.nih.gov |
| Developing Human Pluripotent Stem Cell Tools for Region-Specific Pain Circuits | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,370,000 | September 6, 2024 | August 31, 2027 | IYER, NISHA | reporter.nih.gov |
| Addressing the chronic pain-early cognitive decline comorbidity among older adults; The Active Brains study | NIH | National Institute on Aging | 2022 to 2025 | $2,366,771 | February 1, 2022 | January 31, 2027 | VRANCEANU, ANA-MARIA | reporter.nih.gov |
| MECHANISMS OF VISCERAL PAIN DRIVEN BY SMALL INTESTINAL MICROBIOTA | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,366,065 | September 19, 2023 | July 31, 2028 | KASHYAP, PURNA C | reporter.nih.gov |
| Enhancing modulation Effect of Baduanjin through Non-invasive Neuromodulation for knee Osteoarthritis | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $2,363,880 | August 4, 2023 | May 31, 2028 | KONG, JIAN | reporter.nih.gov |
| Complex inflammatory mechanisms and therapeutic targeting in endometriosis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,360,570 | April 1, 2021 | March 31, 2027 | HAYASHI, KANAKO | reporter.nih.gov |
| Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain (DIRECTPain) | NIH | National Institute of Nursing Research | 2022 to 2025 | $2,358,097 | September 21, 2022 | June 30, 2027 | SORGE, ROBERT | reporter.nih.gov |
| Toolkit for Optimal Recovery after Orthopedic Injury; A multi-site feasibility study to prevent persistent pain and disability | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,355,817 | May 1, 2020 | April 30, 2025 | VRANCEANU, ANA-MARIA | reporter.nih.gov |
| Electrophysiological and ultrasound quantitative biomarkers for myofascial pain | NIH | National Center for Complementary & Integrative Health | 2022 | $2,351,578 | September 19, 2022 | August 31, 2025 | RUTKOVE, SEWARD B. | reporter.nih.gov |
| Imaging of Joint Response to Physiological Stress with Age, Sex and in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,351,319 | May 1, 2022 | February 28, 2027 | KOGAN, FELIKS | reporter.nih.gov |
| Internet-Delivered Pain Self-Management to Reduce Pain and Interference in Chronic Pancreatitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,338,773 | September 1, 2023 | July 31, 2028 | PALERMO, TONYA M | reporter.nih.gov |
| Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,333,844 | April 1, 2022 | February 28, 2027 | MA, YAJUN | reporter.nih.gov |
| Photobiomodulation for the management of Temporomandibular disorder pain | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,330,492 | July 1, 2022 | December 31, 2026 | RIBEIRO-DASILVA, MARGARETE C | reporter.nih.gov |
| Comparative Mechanisms (Mediators, Moderators) of Psychosocial Chronic Pain Treatments | NIH | National Institute of Nursing Research | 2022 to 2024 | $2,327,983 | September 26, 2022 | June 30, 2026 | BURNS, JOHN W. | reporter.nih.gov |
| Axonal transport and chemotherapy induced peripheral neuropathy | NIH | National Cancer Institute | 2022 to 2025 | $2,319,802 | April 1, 2016 | June 30, 2027 | SEGAL, ROSALIND A. | reporter.nih.gov |
| Leveraging a National Pediatric Health Learning System for Phenotyping Pediatric Chronic Primary Pain to Advance Timely Patient-Centered Care | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $2,319,459 | September 19, 2025 | July 31, 2030 | PALERMO, TONYA M | reporter.nih.gov |
| Examining the synergistic effects of cannabis and prescription opioid policies on chronic pain, opioid prescribing, and opioid overdose | NIH | National Institute on Drug Abuse | 2021 to 2023 | $2,319,128 | January 1, 2019 | November 30, 2025 | CERDA, MAGDALENA | reporter.nih.gov |
| Immune Functions of Cutaneous Nociceptors | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,315,978 | March 1, 2017 | May 31, 2027 | KAPLAN, DANIEL H | reporter.nih.gov |
| Psychophysical distillation of pure pain by nociceptive-specific heating | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,314,276 | August 7, 2024 | July 31, 2027 | HARPER, DANIEL ELLIOTT | reporter.nih.gov |
| Electrophysiological and ultrasound quantitative biomarkers for myofascial pain | NIH | National Center for Complementary & Integrative Health | 2025 | $2,313,780 | September 19, 2022 | August 31, 2027 | RUTKOVE, SEWARD B. | reporter.nih.gov |
| Regulation of Peripheral Neuropathic Pain by B Cells | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,308,227 | March 15, 2022 | February 28, 2027 | GRACE, PETER M | reporter.nih.gov |
| Multi-site Randomized Clinical Trial of FIT Teens for Juvenile Fibromyalgia | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $2,307,295 | June 21, 2017 | May 31, 2024 | KASHIKAR-ZUCK, SUSMITA | reporter.nih.gov |
| Focused Ultrasound Neuromodulation of Dorsal Root Ganglion for Noninvasive Mitigation of Low Back Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $2,304,494 | September 25, 2019 | August 31, 2025 | RIEKE, VIOLA | reporter.nih.gov |
| Development of MRGPRX1 positive allosteric modulators as non-addictive therapies for neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,299,466 | September 30, 2019 | August 31, 2024 | TSUKAMOTO, TAKASHI | reporter.nih.gov |
| Music4Pain Network: A research network to advance the study of mechanisms underlying the effects of music and music-based interventions on pain. | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $2,299,092 | September 21, 2023 | August 31, 2028 | BRADT, JOKE | reporter.nih.gov |
| Discovery and Validation of a Novel Response Biomarker Signature for Painful Peripheral Neuropathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,298,698 | September 1, 2022 | April 30, 2026 | NEMENOV, MIKHAIL I. | reporter.nih.gov |
| Impact of Amygdala Lateralization on Processing and Modulation of Bladder Pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,294,587 | August 1, 2018 | August 31, 2028 | KOLBER, BENEDICT J | reporter.nih.gov |
| Joint Pain on a Chip: Mechanistic Analysis Therapeutic Targets and an Empirical Strategy for Personalized Pain Management | NIH | National Center for Advancing Translational Sciences | 2021 | $2,287,391 | September 26, 2019 | July 31, 2025 | GOLD, MICHAEL S | reporter.nih.gov |
| Development and identification of magnetic resonance, electrophysiological, and fiber-optic imaging biomarkers of myofascial pain | NIH | National Center for Complementary & Integrative Health | 2022 | $2,284,469 | September 20, 2022 | August 31, 2025 | HU, SONG | reporter.nih.gov |
| A prolactin-mediated neuroendocrine link between stress-induced latent sensitization and female-selective pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,283,646 | August 1, 2021 | July 31, 2027 | PORRECA, FRANK | reporter.nih.gov |
| Peripheral and Central Pathways of α3 Glycine Receptors as Non-Opioid Molecular Targets to Treat Pain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,282,554 | May 1, 2022 | January 31, 2027 | XU, YAN | reporter.nih.gov |
| Neural Mechanisms Underlying IC/BPS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,281,071 | May 5, 2021 | February 28, 2027 | SAMINENI, VIJAY K | reporter.nih.gov |
| Imaging of pain sources in myofascial pain syndrome | NIH | National Institute of Biomedical Imaging and Bioengineering | 2024 | $2,280,771 | September 6, 2024 | August 31, 2027 | GOLD, GARRY E | reporter.nih.gov |
| STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,276,480 | April 1, 2022 | January 31, 2027 | ROTH, BRYAN L. | reporter.nih.gov |
| Delivery of an At-Home Nonpharmacologic Intervention (Transcranial Neurostimulation) to Mitigate Pain in Patients with End Stage Kidney Disease Receiving Hemodialysis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,272,259 | December 1, 2021 | November 30, 2026 | REID, MANNEY CARRINGTON | reporter.nih.gov |
| Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment (PROSPECTS) | NIH | National Institute on Aging | 2021 to 2024 | $2,271,824 | September 30, 2020 | May 31, 2026 | RUNDELL, SEAN DANIEL | reporter.nih.gov |
| Move and Snooze: Adding insomnia treatment to an exercise program to improve pain outcomes in older adults with knee osteoarthritis | NIH | National Institute on Aging | 2023 to 2025 | $2,261,590 | September 30, 2023 | June 30, 2028 | WHIBLEY, DANIEL | reporter.nih.gov |
| Amygdala kappa opioid system involvement in opioid relapse in pain states | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,256,959 | May 1, 2022 | February 28, 2027 | CAHILL, CATHERINE M | reporter.nih.gov |
| Molecular and Computational Dissection of Cold Nociception | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,254,672 | July 15, 2019 | July 31, 2029 | CYMBALYUK, GENNADY S | reporter.nih.gov |
| Moving beyond the Pain-Suicidality Link: An Investigation of Fluctuations in Social Threat and Neural Response to Social Threat in Momentary Pain and Proximal Risk for Suicidal Ideation in Adolescence | NIH | National Institute of Mental Health | 2023 to 2025 | $2,253,234 | July 1, 2023 | April 30, 2028 | OPPENHEIMER, CAROLINE | reporter.nih.gov |
| Spinal root stimulation for restoration of function in lower-limb amputees | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,252,657 | September 25, 2017 | April 30, 2024 | FISHER, LEE E | reporter.nih.gov |
| Exploring the EphB2-NMDA receptor interaction in spinal cord injury-induced neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,249,630 | September 1, 2018 | June 30, 2029 | LEPORE, ANGELO C. | reporter.nih.gov |
| Validation of neuronal senescence as a target for chronic pain in aging | NIH | National Institute on Aging | 2024 | $2,249,392 | September 15, 2024 | August 31, 2027 | TAWFIK, VIVIANNE L | reporter.nih.gov |
| Development of Opportunities for Research (DOOR) in Dental Schools: Future Academic Interdisciplinary Workforce and Collaborators for the National Dental Practice-Based Research Network (PBRN) | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,241,930 | September 13, 2023 | June 30, 2028 | MCNEIL, DANIEL W | reporter.nih.gov |
| Increased CNS Opioid Exposure by an Acetaminophen-Induced Blood-Brain Barrier Mechanism | NIH | National Institute on Drug Abuse | 2021 to 2024 | $2,240,104 | July 1, 2020 | May 31, 2026 | DAVIS, THOMAS PAUL | reporter.nih.gov |
| The impact of interpersonal stressors and residential stressors on chronic pain in older adults: neurobiological and psychological mechanisms | NIH | National Institute on Aging | 2023 to 2025 | $2,239,708 | April 1, 2023 | January 31, 2028 | TERRY, ELLEN L. | reporter.nih.gov |
| Microbial reactivation of sex steroids and visceral pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,236,187 | August 1, 2022 | May 31, 2027 | RAO, MEENAKSHI | reporter.nih.gov |
| Chronic Postsurgical Pain in Cerebral Palsy | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,233,628 | September 23, 2022 | July 31, 2027 | BURKITT, CHANTEL COURTNEY | reporter.nih.gov |
| Development and Validation of a Multimodal Ultrasound- Based Biomarker for Myofascial Pain | NIH | National Center for Complementary & Integrative Health | 2022 | $2,232,541 | September 19, 2022 | August 31, 2025 | WASAN, AJAY D | reporter.nih.gov |
| The Effect of Medical Cannabis Laws on Health Care Use in Insured Populations with Pain | NIH | National Institute on Drug Abuse | 2021 to 2023 | $2,228,671 | July 1, 2019 | April 30, 2026 | ABRAHAM, AMANDA J | reporter.nih.gov |
| Alternative Mechanisms of Signaling Via Trimeric G Proteins | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,224,007 | September 1, 2014 | March 31, 2026 | GARCIA-MARCOS, MIKEL | reporter.nih.gov |
| Randomized Controlled Trial of Migraine Manager: A Digital Therapeutic Self-Management Tool for Adolescents with Migraine | NIH | National Institute of Nursing Research | 2021 to 2024 | $2,223,497 | August 26, 2020 | May 31, 2026 | HOMMEL, KEVIN | reporter.nih.gov |
| Treatment of cancer pain by lipid mediator Resolvin D1: role of Prostaglandin and Endocannabinoid signaling | NIH | National Cancer Institute | 2021 to 2025 | $2,219,816 | August 5, 2021 | July 31, 2026 | KHASABOV, SERGEY G | reporter.nih.gov |
| Protein biomarkers to predict pain outcomes after total pancreatectomy with islet autotransplant | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,216,262 | September 22, 2023 | July 31, 2027 | BELLIN, MELENA D. | reporter.nih.gov |
| Interpretation and Utility of Novel Composite Structural Endpoints of Cumulative Damage and Disease Activity in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,206,921 | January 23, 2024 | May 31, 2026 | DRIBAN, JEFFREY B | reporter.nih.gov |
| What is Endometriosis? Deep Phenotyping to Advance Diagnosis and Treatment | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $2,201,801 | August 1, 2018 | April 30, 2025 | FAZLEABAS, ASGERALLY T. | reporter.nih.gov |
| Development of KCC2 Neuromodulators to Treat Paralysis After Spinal Cord Injury. | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $2,200,694 | March 1, 2022 | February 28, 2025 | STANICKA, JOANNA | reporter.nih.gov |
| Selective Kv7.2/3 activators for the treatment of neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,200,680 | September 1, 2021 | March 31, 2022 | SIGNORE, ARMANDO | reporter.nih.gov |
| Dissecting Neural Mechanisms Supporting Mind and Body Approaches to Pain Reduction in Youth with Migraine | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,200,367 | April 5, 2019 | September 30, 2025 | POWERS, SCOTT W | reporter.nih.gov |
| Biased Kappa Opioid Agonists as Non-addictive Analgesics | NIH | National Institute on Drug Abuse | 2021 to 2023 | $2,199,015 | April 15, 2019 | August 31, 2025 | MARTIN, THOMAS JEFFREY | reporter.nih.gov |
| In vivo mechanisms mediating sickle cell vaso-occlusion and organ damage | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,197,616 | September 30, 2001 | August 31, 2025 | KELLY, LIBUSHA | reporter.nih.gov |
| Mechanistic-Based Treatment of Interstitial Cystitis/Bladder Pain Syndrome | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,193,826 | May 5, 2023 | February 29, 2028 | MCKERNAN, LINDSEY COLMAN | reporter.nih.gov |
| Cellular signaling mechanisms that drive persistent hyperexcitability in nociceptors | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,193,348 | August 15, 2015 | July 31, 2030 | DESSAUER, CARMEN W. | reporter.nih.gov |
| Epidermal Nonpeptidergic Nerves Modulate Cutaneous Immunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,191,191 | July 15, 2020 | June 30, 2025 | KAPLAN, DANIEL H | reporter.nih.gov |
| Functional and histological changes to peripheral innervation following spinal cord stimulation in patients with painful diabetic neuropathy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,189,785 | September 12, 2023 | July 31, 2028 | TOWNSEND, KRISTY L | reporter.nih.gov |
| Role of Lateral Hypothalamic Neurotensin Neurons in Energy Balance | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,189,758 | September 15, 2014 | January 31, 2028 | LEINNINGER, GINA MARIE | reporter.nih.gov |
| Diverging Effects of Closeness in Older Adults with Chronic Low Back Pain and Spousal Caregivers | NIH | National Institute on Aging | 2021 to 2024 | $2,189,028 | February 15, 2020 | November 30, 2025 | MARTIRE, LYNN M. | reporter.nih.gov |
| Monitoring acute and longer-term effects of cannabis on psychomotor performance in daily life in medical cannabis patients | NIH | National Institute on Drug Abuse | 2023 to 2025 | $2,187,146 | August 15, 2023 | June 30, 2029 | CHUNG, TAMMY | reporter.nih.gov |
| Supplement to Promote Diversity, Inclusion, and Career Development of a Female Scientist | NIH | National Cancer Institute | 2021 to 2022 | $2,183,954 | December 31, 2021 | August 23, 2023 | ALEMAN GUILLEN, FERNANDO | reporter.nih.gov |
| Palliative care needs and outcomes for dementia patients | NIH | National Institute on Aging | 2021 to 2023 | $2,183,654 | September 30, 2018 | May 31, 2025 | PERIYAKOIL, VYJEYANTHI S | reporter.nih.gov |
| Lipoteichoic acid mediated modulation of chronic pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,182,686 | August 1, 2016 | June 30, 2027 | THUMBIKAT, PRAVEEN | reporter.nih.gov |
| Biomarkers to stratify pain severity and type in pancreatic disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,181,860 | August 15, 2023 | May 31, 2027 | STEEN, HANNO | reporter.nih.gov |
| Myeloid lineage targeting to improve recovery from injury and surgery: Cellular and molecular mechanism | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,181,628 | September 15, 2020 | July 31, 2030 | TAWFIK, VIVIANNE L | reporter.nih.gov |
| Neuromodulatory regulation of synaptic plasticity in spinal nociceptive circuits | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,180,687 | April 1, 2022 | May 31, 2026 | BACCEI, MARK L | reporter.nih.gov |
| Personalizing Perioperative Preventive Analgesia: Translational Studies Investigating the Biopsychosocial Underpinnings of Enhanced Pain Propensity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,178,571 | September 1, 2018 | September 19, 2025 | SCHREIBER, KRISTIN | reporter.nih.gov |
| Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings | NIH | National Institute on Drug Abuse | 2021 to 2023 | $2,174,053 | February 15, 2019 | January 31, 2026 | STEIN, MICHAEL D | reporter.nih.gov |
| The role of neuroinflammation in human peripheral neuropathic pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,171,620 | July 1, 2022 | February 28, 2028 | LOGGIA, MARCO LUCIANO | reporter.nih.gov |
| Sensory Amplifications as Biomarkers of Migraine Progression | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,169,126 | April 15, 2023 | September 30, 2026 | BRENNAN, KEVIN CHRISTOPHER | reporter.nih.gov |
| Equity Using Interventions for Pain and Depression (EQUIPD) | NIH | National Institute of Nursing Research | 2024 | $2,166,321 | September 21, 2022 | April 30, 2027 | MATTHIAS, MARIANNE S | reporter.nih.gov |
| Opioid Prescribing Practices and Health Outcomes among Patients with Alzheimer's Disease and Related Dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,165,511 | September 1, 2022 | May 31, 2027 | WEI, YU-JUNG “JENNY” | reporter.nih.gov |
| Sex-specific mechanisms underlying the effects of pain on opioid seeking | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,163,671 | September 15, 2022 | June 30, 2027 | MORON-CONCEPCION, JOSE A | reporter.nih.gov |
| Behavioral and Neural Phenotypes of Primary Dysmenorrhea in Adolescents | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $2,163,490 | September 26, 2019 | April 30, 2026 | PAYNE, LAURA A | reporter.nih.gov |
| Neural correlates of hypoalgesia driven by observation | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,157,462 | August 15, 2019 | July 31, 2025 | COLLOCA, LUANA | reporter.nih.gov |
| The neural bases of placebo effects and their relation to regulatory processes | NIH | National Institute of Mental Health | 2021 to 2023 | $2,155,781 | July 1, 2019 | July 14, 2024 | WAGER, TOR D. | reporter.nih.gov |
| Investigating the Role and Regulation of the MAP7 Family Proteins in Axonal Morphogenesis and Function | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,154,714 | December 15, 2020 | November 30, 2026 | MA, LE | reporter.nih.gov |
| Pain and Motor Learning in Older Adults | NIH | National Institute on Aging | 2022 to 2025 | $2,154,497 | February 1, 2022 | January 31, 2027 | MORTON, SUSANNE M | reporter.nih.gov |
| TRP channel regulation of feeding behavior in Drosophila | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $2,153,052 | September 24, 2021 | August 31, 2027 | JA, WILLIAM W | reporter.nih.gov |
| Modulating single cell types in the sensory nervous system | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,152,157 | July 1, 2022 | June 30, 2027 | SCHMIDT, ERIC W | reporter.nih.gov |
| Explosive Synchronization of Brain Network Activity in Chronic Pain | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $2,141,346 | September 10, 2019 | June 30, 2025 | DASILVA, ALEXANDRE | reporter.nih.gov |
| Pediatric Chronic Headache and COVID-19: Use of Machine Learning and Biobehavioral Analysis to Classify Headache Mechanism and Optimize Treatment Course. | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,140,031 | August 18, 2022 | May 31, 2027 | HOLMES, SCOTT | reporter.nih.gov |
| Development, Evaluation and Translation of Robotic Apparel for Alleviating Low Back Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $2,138,911 | September 26, 2019 | August 31, 2025 | WALSH, CONOR | reporter.nih.gov |
| Tissue Adhesive RNA Interference Nanoparticles to Block Progression of Posttraumatic and Spontaneous Osteoarthritis. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,136,077 | August 22, 2022 | July 31, 2027 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Improvement of Animal Models for TMJ Stem Cell-Based Regeneration | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2023 | $2,135,816 | July 15, 2019 | April 30, 2025 | EMBREE, MILDRED CHRISTINE | reporter.nih.gov |
| Novel Implantable Device to Negate Post-Amputation Pain | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $2,130,641 | September 30, 2021 | September 29, 2024 | LABIB, MOHAMED E | reporter.nih.gov |
| Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations | NIH | National Cancer Institute | 2023 to 2025 | $2,127,624 | September 19, 2023 | August 31, 2028 | VAN CLEAVE, JANET H | reporter.nih.gov |
| Randomized Clinical Trial Intervention to Treat Chronic Pain Among Persons Maintained on Methadone for Opioid Use Disorder | NIH | National Institute on Drug Abuse | 2022 to 2024 | $2,127,553 | June 1, 2022 | January 31, 2025 | ANTOINE, DENIS GODWIN | reporter.nih.gov |
| Sexually dimorphic pain signaling mechanisms | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,121,704 | September 13, 2022 | July 31, 2026 | DONNELLY, CHRISTOPHER RYAN | reporter.nih.gov |
| Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,114,450 | September 15, 2022 | May 31, 2027 | GRIFFITH, JAMES WILLIAM | reporter.nih.gov |
| Neural immunoregulation of post-traumatic autoimmunity | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,111,177 | September 1, 2016 | July 31, 2027 | KINGERY, WADE S | reporter.nih.gov |
| Development of cannabinoid-opioid combination with opioid sparing and synergistic analgesic effects to prevent opioid use disorder and overdose. | NIH | National Institute on Drug Abuse | 2021 to 2022 | $2,110,556 | September 30, 2019 | August 31, 2025 | BRIONES, MARISA | reporter.nih.gov |
| Development and qualification of Talon microIPG to treat Chronic Migraines | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,108,531 | March 1, 2018 | May 31, 2025 | DULAK, GARY | reporter.nih.gov |
| Repurposing FDA-approved oxytocin to treat opioid-induced respiratory depression | NIH | National Institute on Drug Abuse | 2025 | $2,104,389 | July 1, 2025 | June 30, 2027 | MENDELOWITZ, DAVID | reporter.nih.gov |
| Cellular Mechanisms and Therapeutic Potential of NR4A1 in Pain Resolution | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,103,564 | June 1, 2024 | May 31, 2027 | BERTA, TEMUGIN | reporter.nih.gov |
| Total-body PET for assessing myofascial pain | NIH | National Center for Complementary & Integrative Health | 2022 | $2,097,423 | September 19, 2022 | August 31, 2025 | CHAUDHARI, ABHIJIT J | reporter.nih.gov |
| Development of G protein beta gamma subunit inhibitors to improve the safety and efficacy of opioid analgesics | NIH | National Institute on Drug Abuse | 2021 to 2023 | $2,097,030 | September 30, 2019 | July 31, 2024 | SMRCKA, ALAN V. | reporter.nih.gov |
| Molecular mechanisms of TRPA1 regulation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,093,750 | July 1, 2021 | April 30, 2026 | PAULSEN, CANDICE ELAINE | reporter.nih.gov |
| A novel oral immunotherapy for chronic visceral pain of irritable bowel syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,091,549 | September 1, 2024 | August 31, 2026 | YANG, ZHIYONG | reporter.nih.gov |
| Technology Assisted Collaborative Care Implementation Trial | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,082,502 | July 5, 2017 | May 31, 2029 | JHAMB, MANISHA | reporter.nih.gov |
| Role of neuron-satellite glia cell signaling in pelvic pain and visceral cross-sensitization | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,081,882 | September 20, 2023 | July 31, 2028 | SUADICANI, SYLVIA OTTILIE | reporter.nih.gov |
| Supplement to Pathogenesis of HIV-associated sensory neuropathy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,080,000 | September 30, 2021 | August 31, 2026 | YUAN, SUBO | reporter.nih.gov |
| Development of MMP-9 inhibitory monoclonal antibodies to relieve neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,079,796 | August 11, 2025 | July 31, 2027 | GE, XIN | reporter.nih.gov |
| Spinal Cord Nociceptive Circuits that Deliver Outputs to the Brain to Initiate Pain | NIH | National Center for Complementary & Integrative Health | 2023 to 2024 | $2,078,643 | September 15, 2020 | May 19, 2025 | GINTY, DAVID D | reporter.nih.gov |
| Leveraging machine learning to improve risk prediction for chemotherapy inducedneuropathy | NIH | National Cancer Institute | 2021 to 2024 | $2,077,393 | June 1, 2020 | May 31, 2026 | ADAMS, ALYCE SOPHIA | reporter.nih.gov |
| Dissecting the role of mPFC dynorphin circuits in the modulation of different pain states | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,068,842 | September 20, 2024 | August 31, 2027 | SHEETS, PATRICK L | reporter.nih.gov |
| Modulation of the prefrontal cortical network in neuropathic pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,066,533 | April 1, 2020 | March 31, 2025 | MARTINA, MARCO | reporter.nih.gov |
| Plasma metabolite and proteome signatures for migraine classification | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,065,041 | September 1, 2021 | May 31, 2025 | CHASMAN, DANIEL IAN | reporter.nih.gov |
| Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) Syndrome in the Diabetic, Neuropathic Foot | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,064,907 | March 1, 2016 | June 30, 2028 | HASTINGS, MARY K | reporter.nih.gov |
| Glycosylation in ocular surface health and disease | NIH | National Eye Institute | 2021 to 2025 | $2,064,667 | August 1, 2016 | July 31, 2028 | ARGUESO, PABLO | reporter.nih.gov |
| Sensitization of developing sensory neurons after incision | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,061,836 | June 1, 2019 | February 28, 2029 | JANKOWSKI, MICHAEL P | reporter.nih.gov |
| Motor cortical neuromodulation in women with Interstitial Cystitis/Bladder Pain Syndrome: reducing pain by improving brain and muscle activity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,060,111 | August 15, 2020 | April 30, 2026 | KUTCH, JASON J. | reporter.nih.gov |
| Impact of Theory of Mind Training on Brain-to-Brain Patient-Clinician Concordance | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $2,058,989 | April 4, 2023 | January 31, 2028 | NAPADOW, VITALY | reporter.nih.gov |
| Targeting visceral pain through intestinal neuropod cell GUCY2C signaling | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,058,142 | September 19, 2023 | July 31, 2028 | WALDMAN, SCOTT A. | reporter.nih.gov |
| Mechanisms and Modification of Pain Modulatory Capacity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,057,672 | May 15, 2020 | April 30, 2026 | BISHOP, MARK D. | reporter.nih.gov |
| CRP: Noninvasive brain stimulation for chronic pain treatment | NIH | National Institute on Aging | 2025 | $2,055,669 | August 20, 2025 | April 30, 2027 | DIPIETRO, LAURA | reporter.nih.gov |
| Modulating Signaling Endocannabinoids and Fatty Acid Amides | NIH | National Institute on Drug Abuse | 2021 to 2025 | $2,053,125 | December 1, 2021 | November 30, 2026 | BOGER, DALE L | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Duke University | Durham, NC | 70 | $255 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 61 | $128.8 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 90 | $124.8 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 71 | $121.9 million | 0 | $0 |
| University of Florida | Gainesville, FL | 64 | $90.1 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 72 | $89.9 million | 0 | $0 |
| Washington University | Saint Louis, MO | 79 | $84.2 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 54 | $82.2 million | 0 | $0 |
| Stanford University | Stanford, CA | 60 | $72.8 million | 0 | $0 |
| Psychogenics, Inc. | Paramus, NJ | 2 | $55.9 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 35 | $52.8 million | 0 | $0 |
| Yale University | New Haven, CT | 30 | $52.2 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 41 | $48.5 million | 0 | $0 |
| University of Washington | Seattle, WA | 42 | $46.3 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 19 | $41.5 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 33 | $38.4 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 27 | $38.1 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 20 | $37.5 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 30 | $37.2 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 42 | $36.7 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 17 | $36.6 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 44 | $36.5 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 29 | $36.2 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 19 | $36 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 24 | $35.6 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 13 | $31.9 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 27 | $31.9 million | 0 | $0 |
| New York University | New York, NY | 26 | $31.1 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 20 | $31.1 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 16 | $29.6 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 18 | $29.3 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 24 | $28.2 million | 0 | $0 |
| Ohio State University | Columbus, OH | 18 | $28 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 25 | $27.9 million | 0 | $0 |
| University of Texas at Dallas | Richardson, TX | 21 | $27.8 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 30 | $27.3 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 18 | $27.3 million | 0 | $0 |
| University of Iowa | Iowa City, IA | 18 | $27.2 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 20 | $26.5 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 23 | $26.4 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 26 | $25.9 million | 0 | $0 |
| Albany Molecular Research, Inc. | Albany, NY | 1 | $25.7 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 23 | $25.6 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 17 | $25.4 million | 0 | $0 |
| Albert Einstein College of Medicine | Bronx, NY | 14 | $23.2 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 23 | $23.1 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 17 | $22.7 million | 0 | $0 |
| Emory University | Atlanta, GA | 23 | $22.7 million | 0 | $0 |
| University of TX MD Anderson Can CTR | Houston, TX | 20 | $22.4 million | 0 | $0 |
| University of California at Davis | Davis, CA | 16 | $22.4 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 21 | $22 million | 0 | $0 |
| Marshall University Research Corporation | Huntington, WV | 3 | $21.9 million | 0 | $0 |
| Seattle Children's Hospital | Seattle, WA | 13 | $21.8 million | 0 | $0 |
| Medical College of Wisconsin | Milwaukee, WI | 26 | $21.4 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 11 | $20.4 million | 0 | $0 |
| University of Rochester | Rochester, NY | 19 | $20.1 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 17 | $19.6 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 20 | $18.7 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 17 | $17.9 million | 0 | $0 |
| Kaiser Foundation Research Institute | Oakland, CA | 5 | $17.8 million | 0 | $0 |
| University of New England | Biddeford, ME | 12 | $17 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 8 | $16.5 million | 0 | $0 |
| Brown University | Providence, RI | 9 | $16.1 million | 0 | $0 |
| University of Texas Med BR Galveston | Galveston, TX | 12 | $16 million | 0 | $0 |
| Battelle Memorial Institute | Columbus, OH | 1 | $14.8 million | 0 | $0 |
| University of Connecticut | Storrs, CT | 14 | $14 million | 0 | $0 |
| Thomas Jefferson University | Philadelphia, PA | 11 | $13.5 million | 0 | $0 |
| Tufts Medical Center | Boston, MA | 9 | $13.3 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 11 | $12.9 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 11 | $12.8 million | 0 | $0 |
| University of New Mexico | Albuquerque, NM | 2 | $12.5 million | 0 | $0 |
| Zetroz Systems, LLC | Trumbull, CT | 3 | $12.2 million | 0 | $0 |
| Michigan State University | East Lansing, MI | 11 | $12.1 million | 0 | $0 |
| Advanced Bioscience Laboratories, Inc. | Kensington, MD | 1 | $11.8 million | 0 | $0 |
| Marine Biological Laboratory | Woods Hole, MA | 1 | $11.2 million | 0 | $0 |
| SUNY at Buffalo | Amherst, NY | 9 | $11.1 million | 0 | $0 |
| Wake Forest University | Winston Salem, NC | 4 | $10.9 million | 0 | $0 |
| Virginia Commonwealth University | Richmond, VA | 17 | $10.9 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 7 | $10.8 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 16 | $10.5 million | 0 | $0 |
| Drexel University | Philadelphia, PA | 8 | $10.3 million | 0 | $0 |
| Revbio, Inc. | Lowell, MA | 5 | $9.9 million | 0 | $0 |
| University of Vermont & ST Agric College | Burlington, VT | 5 | $9.8 million | 0 | $0 |
| Spaulding Rehabilitation Hospital | Charlestown, MA | 9 | $9.6 million | 0 | $0 |
| Dana-Farber Cancer Inst | Boston, MA | 10 | $9.6 million | 0 | $0 |
| Saint Louis University | Saint Louis, MO | 8 | $9.5 million | 0 | $0 |
| Lohocla Research Corporation | Aurora, CO | 1 | $9.3 million | 0 | $0 |
| Sloan-Kettering Inst Can Research | New York, NY | 8 | $9.3 million | 0 | $0 |
| Texas A&m University Health Science CTR | College Station, TX | 10 | $9.1 million | 0 | $0 |
| Temple Univ of the Commonwealth | Philadelphia, PA | 7 | $9.1 million | 0 | $0 |
| Northern California Institute/res/edu | San Francisco, CA | 3 | $9 million | 0 | $0 |
| University of South Florida | Tampa, FL | 9 | $8.9 million | 0 | $0 |
| University of Colorado at Boulder | Boulder, CO | 7 | $8.7 million | 0 | $0 |
| Centrexion Therapeutics Corporation | Boston, MA | 2 | $8.7 million | 0 | $0 |
| Worcester Polytechnic Institute | Worcester, MA | 2 | $8.5 million | 0 | $0 |
| Pennsylvania State Univ University Park | University Park, PA | 7 | $8.5 million | 0 | $0 |
| Endeavor Health Clinical Operations | Evanston, IL | 5 | $8.4 million | 0 | $0 |
| Harvard Medical School | Boston, MA | 8 | $8.3 million | 0 | $0 |
| University of Chicago | Chicago, IL | 6 | $8.2 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 9 | $7.9 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 1,094 | $737,767,183 | 0 | $0 |
| 2024 | 1,213 | $713,278,919 | 0 | $0 |
| 2023 | 1,268 | $731,482,228 | 0 | $0 |
| 2022 | 1,278 | $752,306,998 | 0 | $0 |
| 2021 | 1,166 | $768,101,298 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.