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Cachexia: 145 NIH awards ($147M) to 83 organizations

145 NIH awards ($147M) in the NIH spending category Cachexia, to 83 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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145 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Moffitt Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$22,007,955February 18, 1998January 31, 2027CLEVELAND, JOHN L.reporter.nih.gov
The von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer: Insights into Oxygen Sensing and Treating Cancers Caused by Undruggable MutationsNIHNational Cancer Institute2021 to 2025$4,888,860September 1, 2016August 31, 2030KAELIN, WILLIAM G.reporter.nih.gov
Systemic regulation of metastasisNIHNational Cancer Institute2021 to 2024$3,947,638September 18, 2018August 31, 2025LYDEN, DAVID CHARLESreporter.nih.gov
Cachexia-mediated FcRn Modulation and Its Impact on Anti-PD1 Therapy in Lung CancerNIHNational Cancer Institute2022 to 2025$3,113,004August 8, 2022July 31, 2027PHELPS, MITCH Areporter.nih.gov
Identifying the Cellular and Molecular Targets of JAK/STAT-Driven Adipose Wasting to Reverse Cancer CachexiaNIHNational Cancer Institute2022 to 2025$2,999,575September 22, 2022August 31, 2027INFANTE, RODNEY Ereporter.nih.gov
Human on a chip systems to investigate disease comorbidities common in the aged populationNIHNational Institute on Aging2021 to 2022$2,967,932April 1, 2018April 30, 2025SHULER, MICHAEL Lreporter.nih.gov
Molecular Imaging and Theranostics of CancerNIHNational Cancer Institute2021 to 2023$2,907,093September 4, 2017March 31, 2025BHUJWALLA, ZAVER M.reporter.nih.gov
COPD cachexia: deciphering the impact of antioxidants, iron and mitochondrial function using 'omics approachesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,723,054June 10, 2021May 31, 2025MCDONALD DONNELLY, MERRY-LYNN NOELLEreporter.nih.gov
Targeting the GDF15-GFRAL system to treat nausea and emesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,667,223August 9, 2021May 31, 2026DE JONGHE, BART Creporter.nih.gov
Optimizing integration of veterinary clinical research findings with human health systems to improve strategies for early detection and interventionNIHNational Center for Advancing Translational Sciences2023 to 2025$2,512,809September 20, 2023June 30, 2028LONDON, CHERYL Areporter.nih.gov
Novel Nanomedicine-Based Therapeutic Approach For Treatment of Cancer CachexiaNIHNational Cancer Institute2021 to 2025$2,226,892May 1, 2024April 30, 2027TARATULA, OLEHreporter.nih.gov
CANCAN - COLDSPRINGNIHNational Cancer Institute2022 to 2025$2,225,345June 22, 2022May 31, 2026JANOWITZ, TOBIASreporter.nih.gov
Sizing and Scaling in Functional Muscle CellsNIHNational Institute of General Medical Sciences2021 to 2025$2,212,596June 1, 2021May 31, 2027BAYLIES, MARY Kreporter.nih.gov
The cytokine code and neural circuits for sensing inflammation stateNIHNational Institute of Mental Health2024 to 2025$2,177,000September 30, 2024July 31, 2029KEPECS, ADAMreporter.nih.gov
Identification of key tumor cell-released factors that induce cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,132,780July 1, 2013March 31, 2026LI, YI-PINGreporter.nih.gov
PQ6: Therapeutic approaches for autonomic and neuroendocrine dysfunction in cancer cachexiaNIHNational Cancer Institute2021 to 2025$2,124,924September 10, 2021August 31, 2026GROSSBERG, AARONreporter.nih.gov
Mechanism of chemotherapy potentiation of muscle wasting in cancer cachexiaNIHNational Cancer Institute2021 to 2025$2,092,178March 2, 2021February 28, 2027LI, YI-PINGreporter.nih.gov
Innate Inflammatory Control of CachexiaNIHNational Institute of General Medical Sciences2021 to 2025$2,072,091August 1, 2020July 31, 2030EWALD, SARAH E.reporter.nih.gov
Characterization of the Insulin to Autophagy Pathway in MusclesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,036,399August 1, 2010May 14, 2025PERRIMON, NORBERTreporter.nih.gov
Upgrade of 3T MRI system to Siemens Vida for metabolism-related human biomedical researchNIHOffice of the Director, National Institutes of Health2025$2,000,000August 1, 2025July 1, 2027CARMICHAEL, OWEN T.reporter.nih.gov
Development of novel therapeutics for cancer cachexiaNIHNational Cancer Institute2023 to 2024$1,987,656April 1, 2023March 31, 2026EBERT, SCOTT MATTHEWreporter.nih.gov
PQ6: Lipocalin-2 as a therapeutic target for prevention of cancer cachexiaNIHNational Cancer Institute2021 to 2025$1,918,262April 1, 2021March 31, 2026ZIMMERS, TERESA Areporter.nih.gov
Preclinical Development of a Novel Gene Therapeutic for Inclusion Body MyositisNIHNational Institute on Aging2022 to 2023$1,877,616September 30, 2022August 31, 2025RODGERS, BUELreporter.nih.gov
The Complement System and Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,856,131August 1, 2022July 31, 2027JUDGE, ANDREW ROBERTreporter.nih.gov
NF-kB Regulation of the Muscle Microenvironment in Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,849,772February 26, 2020June 30, 2025GUTTRIDGE, DENIS Creporter.nih.gov
CANCAN - ROCHESTERNIHNational Cancer Institute2022 to 2025$1,728,753June 22, 2022May 31, 2026MUSTIAN, KAREN M.reporter.nih.gov
CANCAN-RUTGERSNIHNational Cancer Institute2023 to 2025$1,723,505June 22, 2022May 31, 2026WHITE, EILEEN P.reporter.nih.gov
Growth differentiation factor-15 (GDF15) as a novel myocardial hormone in heart failureNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,722,057February 1, 2022January 31, 2027BURKE, MICHAEL Areporter.nih.gov
CANCAN - KaiserNIHNational Cancer Institute2022 to 2025$1,705,380June 22, 2022May 31, 2026CAAN, BETTE Jreporter.nih.gov
IGFBP1 mediates a liver-bone-muscle axis in colorectal cancer cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,650,159September 1, 2022July 31, 2027BONETTO, ANDREAreporter.nih.gov
TWEAK/Fn14/UPR Signaling in Skeletal Muscle WastingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,621,760April 1, 2023January 31, 2028KUMAR, ASHOKreporter.nih.gov
The CANcer Cachexia Action Network (CANCAN): a Multidisciplinary Virtual Institute with the Mission to Cure Cancer CachexiaNIHNational Cancer Institute2024 to 2025$1,415,840June 1, 2024May 31, 2026GONCALVES, MARCUS DASILVAreporter.nih.gov
Control of cancer cachexia via stimulation of resolution of inflammationNIHNational Cancer Institute2024 to 2025$1,401,619January 1, 2024December 31, 2028PANIGRAHY, DIPAKreporter.nih.gov
The Role of Akt in Cell Survival and Cell GrowthNIHNational Institute on Aging2021 to 2023$1,370,232September 1, 1998February 28, 2025HAY, NISSIMreporter.nih.gov
Matricellular proteins of the CNN family as regulators of tumor-induced cachexiaNIHNational Cancer Institute2023 to 2025$1,357,279September 7, 2023August 31, 2028JUDGE, SARAH Mreporter.nih.gov
Targeting Muscle Fatigability During CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,317,536June 3, 2022April 30, 2027PISTILLI, EMIDIO EDWARDreporter.nih.gov
Targeting Transglutaminase 2 in cancer cachexiaNIHNational Cancer Institute2021 to 2024$1,307,284July 1, 2020June 30, 2025ATFI, AZEDDINEreporter.nih.gov
Targeting RANKL for the treatment of muscle and bone defects in cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,279,154December 10, 2022November 30, 2026BONETTO, ANDREAreporter.nih.gov
DEVELOPMENT OF TARGETED APPROACHES IN PREVENTION OF CANCER-CACHEXIANIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,276,939July 1, 2020June 30, 2025GREENE, NICHOLAS PERRYreporter.nih.gov
Metabolic vulnerability due to dysregulated lipid metabolism in PDAC cachexiaNIHNational Cancer Institute2023 to 2025$1,127,838September 22, 2023August 31, 2028GROSSBERG, AARONreporter.nih.gov
Modulating dietary zinc to prevent cachexia and improve survival in cancerNIHNational Cancer Institute2021 to 2023$1,096,903June 1, 2019May 31, 2025ACHARYYA, SWARNALIreporter.nih.gov
Mechanism by which ketogenic diet uncouples tumor growth and overall survivalNIHNational Cancer Institute2024 to 2025$1,062,713June 6, 2024May 31, 2029JANOWITZ, TOBIASreporter.nih.gov
Exploiting the Twist1 network in cancer cachexiaNIHNational Cancer Institute2021 to 2023$1,054,221June 1, 2019May 31, 2025ATFI, AZEDDINEreporter.nih.gov
Protein Nutrition in Experimental UremiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,052,625September 1, 1987June 30, 2028HU, ZHAOYONGreporter.nih.gov
The Role of TGFβ2 and Macrophages in Cancer CachexiaNIHNational Cancer Institute2024 to 2025$1,051,908May 8, 2024April 30, 2029VELAZQUEZ, KANDY Treporter.nih.gov
Rewiring Cancer-Induced Abnormalities in the Vascular BarrierNIHNational Cancer Institute2024 to 2025$1,025,544July 5, 2024June 30, 2026IRUELA-ARISPE, M. LUISAreporter.nih.gov
Factor XIIa is the long-sought activator of circulating renin in heart failure.NIHNational Heart, Lung, and Blood Institute2024 to 2025$1,017,906July 1, 2024June 30, 2028GLADYSHEVA, INNA Preporter.nih.gov
CANCAN - SALKNIHNational Cancer Institute2022 to 2024$993,523June 22, 2022May 31, 2025AYRES, JANELLE Sreporter.nih.gov
A Meal Delivery and Exercise Intervention to Increase Resilience in Homebound Older AdultsNIHNational Institute on Aging2021 to 2025$955,395May 1, 2021February 28, 2027LEE, JESSICA LANreporter.nih.gov
Hepatic metabolic reprogramming drives pancreatic cancer cachexiaNIHNational Cancer Institute2021 to 2024$943,806July 3, 2020June 30, 2025GROSSBERG, AARONreporter.nih.gov
Exosomes as Endocrine Signaling Molecules in Cancer CachexiaNIHNational Cancer Institute2021 to 2022$870,788May 10, 2018April 30, 2023MARKS, DANIEL L.reporter.nih.gov
Cancer Gene Discovery to Identify Targetable TargetsNIHNational Cancer Institute2021$843,904September 11, 2015August 31, 2022CROCE, CARLO Mreporter.nih.gov
The role of unacylated ghrelin in age-associated progressive muscle weakness and cachexia elicited by cancer.NIHNational Institute on Aging2022 to 2024$839,466February 15, 2020January 31, 2026AHN, BUMSOOreporter.nih.gov
Cell autonomous and non autonomous induction of degeneration in DrosophilaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$780,506June 1, 2018January 31, 2024STERN, MICHAEL Jreporter.nih.gov
Inference of Common Pathways Underlying Neurodegeneration & Other Age-Progressive DiseasesNIHNational Institute on Aging2021 to 2022$749,942September 30, 2018May 31, 2024SHMOOKLER REIS, ROBERT JOSEPHreporter.nih.gov
The Musculoskeletal Cost of Organ RepairNIHNational Institute of General Medical Sciences2021 to 2022$735,732June 1, 2020December 31, 2022KONIARIS, LEONIDAS G.reporter.nih.gov
Cellular and Molecular Determinants of Post-Burn MyopathyNIHNational Institute of General Medical Sciences2024 to 2025$734,154August 1, 2024May 31, 2029OWEN, ALLISON M.reporter.nih.gov
Training and Research on Mechanisms of Pancreatic Cancer Associated Muscle Wasting and Related TherapiesNIHNational Cancer Institute2021 to 2025$713,515August 9, 2021July 31, 2026COLE, CALVIN LLOYDreporter.nih.gov
Role of Twist2+ myogenic progenitor cells in adult skeletal muscleNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$698,544May 15, 2018April 30, 2024LIU, NINGreporter.nih.gov
Role of BNIP3 and mitophagy in muscle atrophy and cancer cachexiaNIHNational Cancer Institute2025$698,076December 5, 2024November 30, 2029MACLEOD, KAY Freporter.nih.gov
CANCAN - CambridgeNIHNational Cancer Institute2022 to 2024$681,975June 22, 2022May 31, 2025BIFFI, GIULIAreporter.nih.gov
Muscle Fibrosis in CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$677,160September 1, 2022August 31, 2027ROY, ISHANreporter.nih.gov
CANCAN ? CORNELLNIHNational Cancer Institute2022 to 2023$656,764June 22, 2022May 31, 2024GONCALVES, MARCUS DASILVAreporter.nih.gov
CANCAN - HarvardNIHNational Cancer Institute2022 to 2024$626,777June 22, 2022May 31, 2025PERRIMON, NORBERTreporter.nih.gov
A SkeleTal muscle Recovery Intervention with Dietary protein in Heart Failure (ASTRID-HF)NIHNational Heart, Lung, and Blood Institute2024 to 2025$626,725March 15, 2023January 31, 2027VEST, AMANDA RUTHreporter.nih.gov
CANcer Cachexia Action Network/CANCANNIHNational Cancer Institute2022 to 2024$624,282September 8, 2022May 31, 2025JAMAL-HANJANI, MARIAMreporter.nih.gov
Targeting cancer cachexia drivers using antibody-based approachesNIHNational Cancer Institute2024 to 2025$617,343December 11, 2023March 31, 2025ATFI, AZEDDINEreporter.nih.gov
CANCAN-HARVARDTHCHANNIHNational Cancer Institute2022 to 2024$599,304June 22, 2022May 31, 2025HUI, SHENGreporter.nih.gov
Mechanisms driving muscle wasting and adipose tissue loss in the UBF mKO mouseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$590,958September 20, 2024February 28, 2027FIGUEIREDO, VANDRE CASAGRANDEreporter.nih.gov
Burn induces hypermetabolism via browning of the white adipose tissueNIHNational Institute of General Medical Sciences2022 to 2023$570,500May 1, 2022April 30, 2025JESCHKE, MARC GERHARDreporter.nih.gov
Assessing if tumor induced muscle cachexia is initiated by defects in Myosin Heavy Chain production and localization in a Drosophila tumor modelNIHNational Institute of General Medical Sciences2023 to 2025$512,380September 15, 2023July 31, 2027ATKINS, MARDELLE RENEEreporter.nih.gov
The Musculoskeletal Cost of Organ RepairNIHNational Institute of General Medical Sciences2022 to 2023$497,064June 1, 2020February 28, 2025KONIARIS, LEONIDAS G.reporter.nih.gov
The Extracellular Matrix in Muscle AtrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$488,037January 15, 2020December 31, 2023TALBERT, ERIN Ereporter.nih.gov
Targeting NLRP3 inflammasome for treating muscle complications of chronic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$473,938August 15, 2020May 31, 2023MAK, ROBERT Hreporter.nih.gov
Molecular pathogenesis of skeletal muscle atrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$472,103July 22, 2017May 31, 2023ADAMS, CHRISTOPHER Mreporter.nih.gov
Using the gut microbiome to treat skeletal muscle atrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$458,907February 1, 2025January 31, 2030MCCARTHY, JOHN JOSEPHreporter.nih.gov
CANCAN - PENNINGTONNIHNational Cancer Institute2022 to 2025$456,589June 22, 2022May 31, 2026HEYMSFIELD, STEVENreporter.nih.gov
Managing metabolic disruption in pancreatic cancer to prevent weight loss and improve quality of lifeNIHNational Cancer Institute2023 to 2025$455,112August 1, 2023June 30, 2026FLORY, JAMES Hreporter.nih.gov
Development and utility of a wearable sensor for continuous monitoring of nutrients and hormones in subjects with chronic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$446,172June 10, 2022May 31, 2025NISTALA, RAVIreporter.nih.gov
Mitokines as new targets for fatigue induced by mitochondrial stressNIHNational Institute of Neurological Disorders and Stroke2022$445,500September 15, 2022August 31, 2024DANTZER, ROBERTreporter.nih.gov
Targeting RANKL for the treatment of muscle and bone defects in cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$441,832July 12, 2021May 31, 2026BONETTO, ANDREAreporter.nih.gov
Targeting the Metabolic Basis of Cachexia in Pancreatic CancerNIHNational Cancer Institute2021$434,065December 16, 2016May 11, 2022SINGH, PANKAJ KUMARreporter.nih.gov
Molecular Imaging and Metabolotheranostics of PDAC-Induced CachexiaNIHNational Cancer Institute2025$432,889April 1, 2025March 31, 2030BHUJWALLA, ZAVER M.reporter.nih.gov
FoxO signaling and skeletal muscle atrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$431,531August 1, 2011August 31, 2023JUDGE, ANDREW ROBERTreporter.nih.gov
Skeletal Muscle Wasting as a Modifiable Target for Treating Patients with Heart Failure with Reduced Ejection FractionNIHNational Heart, Lung, and Blood Institute2023$430,492March 15, 2023January 31, 2024VEST, AMANDA RUTHreporter.nih.gov
The musculoskeletal cost of metastatic colorectal cancerNIHNational Cancer Institute2025$423,084May 5, 2025April 30, 2030HUOT, JOSHUAreporter.nih.gov
A novel multi-omics approach to explore mechanisms of lean mass recoveryNIHNational Institute of General Medical Sciences2025$421,829June 1, 2025March 31, 2030GERSON, ALEXANDER R.reporter.nih.gov
Regulation of exercise physiology by mammalian cryptochromesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$416,667December 7, 2017November 30, 2021LAMIA, KATJA Areporter.nih.gov
The role of the gut microbiome in susceptibility to Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$413,689July 3, 2023June 30, 2026WOLF, ASHLEY ROBINreporter.nih.gov
Burn induces hypermetabolism via browning of the white adipose tissueNIHNational Institute of General Medical Sciences2021 to 2022$407,497May 1, 2020July 31, 2022JESCHKE, MARC GERHARDreporter.nih.gov
MuRF1 substrates and mechanisms of skeletal muscle atrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$406,984April 1, 2024March 31, 2026BODINE, SUE Creporter.nih.gov
Sex-dependent rescue of cancer cachexiaNIHNational Cancer Institute2021$397,258April 15, 2021March 31, 2024TALBERT, ERIN Ereporter.nih.gov
Development of a clinically relevant mouse model of lung cancer cachexia to study pathoetiology and therapeutic strategiesNIHNational Cancer Institute2023 to 2024$391,998August 4, 2023July 31, 2026TOTH, MICHAEL Jreporter.nih.gov
Mediators of Pancreatic Cancer-Associated CachexiaNIHNational Cancer Institute2021 to 2022$388,715December 4, 2020November 30, 2023CRUZ-MONSERRATE, ZOBEIDAreporter.nih.gov
Delineating the contribution of muscle wasting to tumor progressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$383,570September 20, 2023August 31, 2025DOLES, JASONreporter.nih.gov
The Role of Platelets in Cancer CachexiaNIHNational Cancer Institute2024 to 2025$373,830March 5, 2024February 28, 2027VELAZQUEZ, KANDY Treporter.nih.gov
The Role of AMPK in Regulating Muscle Mass and Function in Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$366,363June 1, 2023May 31, 2028KERR, HAIMING LIUreporter.nih.gov
The CANcer Cachexia Action Network (CANCAN):a Multidisciplinary Virtual Institutewith the Mission to Cure Cancer CachexiaCANCAN - BEATSONNIHNational Cancer Institute2022 to 2024$357,489June 22, 2022May 31, 2025LEWIS, DAVID Yreporter.nih.gov
Interrogating functional and molecular properties of PAX7+ putative skeletal muscle stem/progenitor cells derived from human iPSCs of healthy donors and Duchenne muscular dystrophy patientsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$348,502March 1, 2017February 28, 2022LEE, GABSANGreporter.nih.gov
Utilizing senolytics to enhance the response to exercise in cachectic miceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$341,600August 15, 2024July 31, 2026DUNGAN, CORYreporter.nih.gov
MUC16 in Pancreatic Cancer Progression and MetastasisNIHNational Cancer Institute2021$338,280April 1, 2017March 31, 2023RADHAKRISHNAN, PRAKASHreporter.nih.gov
A Novel Small Molecule Oral Therapeutic to Prevent and Reverse Skeletal Muscle Atrophy in Aging AdultsNIHNational Institute on Aging2023$322,432September 1, 2023August 31, 2025WILEY, ANDREA LEAHreporter.nih.gov
The Role of the Gut Microbiome in Post-Sepsis Skeletal Muscle AtrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$304,946April 1, 2024March 31, 2029BONGERS, KALE Sreporter.nih.gov
Using phosphorylation signatures of drug perturbagens to identify exercise-mimetic compoundsNIHOffice of the Director, National Institutes of Health2021$298,188September 22, 2021September 21, 2022MANI, DENKANIKOTA Rreporter.nih.gov
Electrical impedance myography (EIM) to detect and track cancer cachexiaNIHNational Cancer Institute2025$263,052September 1, 2025August 31, 2027DICKINSON, DAVID P.reporter.nih.gov
Targeting Perp in PDAC tumor and cancer cachexiaNIHNational Cancer Institute2024 to 2025$262,144April 1, 2024August 10, 2025DASGUPTA, ANEESHAreporter.nih.gov
Therapeutic antibody for cancer-associated cachexiaNIHNational Cancer Institute2021$252,282July 13, 2021June 30, 2023YU, BOreporter.nih.gov
Mechanistic study of skeletal muscle proteolysis induced by breast cancer-secreted extracellular vesiclesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$250,000September 20, 2022August 31, 2024WANG, SHIZHEN EMILYreporter.nih.gov
Targeting Perp in PDAC tumor and cancer cachexiaNIHNational Cancer Institute2025$249,000April 1, 2024July 31, 2028DASGUPTA, ANEESHAreporter.nih.gov
Targeting KLF10 to prevent cancer-associated muscle lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$239,239September 18, 2023August 31, 2025DOLES, JASONreporter.nih.gov
Elucidating the role of hepatic ketogenesis in pancreatic cancer cachexia and recoveryNIHNational Cancer Institute2024 to 2025$236,082February 1, 2024January 31, 2026ARNESON-WISSINK, PAIGE Creporter.nih.gov
CANCAN-RUTGERSNIHNational Cancer Institute2022$223,182June 22, 2022May 31, 2023WHITE, EILEEN P.reporter.nih.gov
Targeting GDF15-GFRAL signaling in mitochondrial myopathiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$216,113June 1, 2025May 31, 2027D'AURELIO, MARILENAreporter.nih.gov
CANCAN-GlasgowNIHNational Cancer Institute2022 to 2023$209,850June 22, 2022May 31, 2024MADDOCKS, OLIVERreporter.nih.gov
Characterization of Maf function in muscle atrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$190,160August 1, 2024July 31, 2026DOS SANTOS, MATTHIEUreporter.nih.gov
Targeting circulating HSP70 and HSP90 for the treatment of cancer cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$166,452July 8, 2020June 30, 2022LI, YI-PINGreporter.nih.gov
The role of adrenergic signaling in cancer cachexia-associated cardiac remodelingNIHNational Heart, Lung, and Blood Institute2023 to 2025$161,206August 25, 2023February 24, 2027DIBA, PARHAMreporter.nih.gov
Integrative Multi-Omics of Metabolomics and Epigenetics to Explore thePathophysiology of Cachexia and Survival in Head and Neck SquamousCell CarcinomaNIHNational Cancer Institute2025$156,500August 1, 2025July 31, 2027ELDRIDGE, RONALD Creporter.nih.gov
Metastatic Bone Disease and IL-6 as Drivers of Cachexia in Kidney CancerNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$156,210May 7, 2025April 30, 2030COLLIER, CHRISTOPHER DAVIDreporter.nih.gov
The Role of Hypoketonemia in the Cancer Anorexia-Cachexia SyndromeNIHNational Cancer Institute2021$149,682August 1, 2018May 1, 2022GONCALVES, MARCUS DASILVAreporter.nih.gov
Hyperphosphatemia Contributes to Skeletal Muscle Atrophy in the Absence and Presence of Chronic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$143,421May 1, 2022April 30, 2025HEITMAN, KYLIEreporter.nih.gov
AVGN7, a Novel Gene Therapeutic for Treating Cancer CachexiaNIHNational Cancer Institute2021$134,809September 25, 2017August 31, 2022RODGERS, BUELreporter.nih.gov
Determining how cancer cachexia influences gluconeogenesisNIHNational Cancer Institute2025$133,955August 7, 2025July 31, 2027ZHANG, YICHIreporter.nih.gov
Effect of a ghrelin receptor agonist on muscle and boneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$131,551April 10, 2019February 29, 2024DAWSON-HUGHES, BESSreporter.nih.gov
Transcriptional Regulation and Therapeutic Modulation of Muscle CDKN1A in Cancer CachexiaNIHNational Cancer Institute2025$130,501July 9, 2025June 30, 2027WANG, HUIreporter.nih.gov
Adipose tissue as a novel facilitator of tumor growth and cachexiaNIHNational Cancer Institute2025$129,624July 14, 2025June 30, 2026SNOKE, DEENA Breporter.nih.gov
Chronic aryl hydrocarbon receptor activation and skeletal myopathy in chronic kidney diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$122,186August 16, 2021May 7, 2024THOME, TRACEreporter.nih.gov
REWIRING CANCER-INDUCED ABNORMALITIES IN THE VASCULAR BARRIERNIHNational Cancer Institute2023$120,000September 19, 2023May 31, 2024IRUELA-ARISPE, M. LUISAreporter.nih.gov
CANCAN - Spatially resolved metabolic measurements in cells and organs during cancer cachexiaNIHNational Cancer Institute2024$114,726June 1, 2024May 31, 2025DAVIDSON, SHAWN MICHAELreporter.nih.gov
Investigating cancer-associated cachexia in genetic subtypes of lung cancerNIHNational Cancer Institute2024 to 2025$97,572May 13, 2024May 12, 2028CROSS, MICHAELreporter.nih.gov
The role of unacylated ghrelin on age-associated progressive muscle weakness and cachexia elicited by cancerNIHNational Institute on Aging2021$95,979February 15, 2020January 31, 2022AHN, BUMSOOreporter.nih.gov
Microbiome-Mitochondrial Interactions Driving Cancer-Induced Cachexia in the Obese StateNIHNational Cancer Institute2024 to 2025$79,462September 1, 2024November 30, 2025CARDACI, THOMASreporter.nih.gov
Elucidating the role of xanthine oxidoreductase in regulating muscle dysfunction in cancer cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$77,284September 23, 2025MILLER, SPENCER GRAHAMreporter.nih.gov
Muscle Circadian Clock Disruption as a Cancer Cachexia ModifierNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$73,408July 1, 2025June 30, 2028MORENA CLARK, FRANCIELLYreporter.nih.gov
Development of Dietary Quercetin to Treat Muscle Wasting DisordersNIHNational Center for Complementary & Integrative Health2021$52,000September 15, 2020September 14, 2021VANDERVEEN, BRANDONreporter.nih.gov
Impact of obesity on chemotherapy-induced muscle mitochondrial dysfunctionNIHNational Cancer Institute2023 to 2024$49,531July 1, 2023August 31, 2024CARDACI, THOMASreporter.nih.gov
The Role of Lipocalin 2 in Cancer CachexiaNIHNational Cancer Institute2021$47,795July 30, 2020May 24, 2022OLSON, BRENNAN GLENNreporter.nih.gov
Evaluating the role of the tumor macroenvironment in cancer cachexiaNIHNational Cancer Institute2025$44,158August 1, 2025July 30, 2027ARREOLA, ALEXreporter.nih.gov
The Role of the Gut Microbiome in Post-Sepsis Skeletal Muscle AtrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$35,847April 1, 2024June 27, 2024BONGERS, KALE Sreporter.nih.gov
2025 Cancer Cachexia Conference: Cachexia management today and potential treatments for tomorrowNIHNational Cancer Institute2025$35,000September 1, 2025June 30, 2026JUDGE, ANDREW ROBERTreporter.nih.gov
The Role of Oncostatin M in the PDAC tumor microenvironment and macroenvironmentNIHNational Cancer Institute2021$30,306August 3, 2021August 2, 2023JENGELLEY, DAENIQUEreporter.nih.gov
FGF21-IGFBP1 axis mediates musculoskeletal deficits in colorectal cancer cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$23,267June 1, 2022July 31, 2022HUOT, JOSHUAreporter.nih.gov
Enhancing Diversity and Addressing Disparities at the 7th Cancer Cachexia ConferenceNIHNational Cancer Institute2023$15,000September 19, 2023August 31, 2024ZIMMERS, TERESA Areporter.nih.gov
Nutrient Sensing and Signaling in MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$10,000July 9, 2024July 31, 2025ANTHONY, TRACY G.reporter.nih.gov
The Role of Leukocytes in the Hypothalamus in Cancer CachexiaNIHNational Cancer Institute2021$574March 1, 2018March 8, 2021BURFEIND, KEVIN GLENNreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
H. Lee Moffitt Cancer CTR & Res InstTampa, FL1$22 million0$0
Oregon Health & Science UniversityPortland, OR11$7.9 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX4$5.3 million0$0
Weill Medical Coll of Cornell UnivNew York, NY4$5 million0$0
Dana-Farber Cancer InstBoston, MA1$4.9 million0$0
Ohio State UniversityColumbus, OH3$4.3 million0$0
Ut Southwestern Medical CenterDallas, TX3$3.9 million0$0
University of FloridaGainesville, FL6$3.9 million0$0
Johns Hopkins UniversityBaltimore, MD3$3.7 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY2$3.3 million0$0
Virginia Commonwealth UniversityRichmond, VA3$3 million0$0
Hesperos, LLCOrlando, FL1$3 million0$0
University of Colorado DenverAurora, CO2$2.9 million0$0
University of Alabama at BirminghamBirmingham, AL2$2.9 million0$0
Indiana University IndianapolisIndianapolis, IN9$2.7 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY2$2.7 million0$0
University of PennsylvaniaPhiladelphia, PA1$2.7 million0$0
Harvard Medical SchoolBoston, MA2$2.7 million0$0
Tufts University BostonBoston, MA2$2.6 million0$0
LSU Pennington Biomedical Research CTRBaton Rouge, LA2$2.5 million0$0
University of RochesterRochester, NY2$2.4 million0$0
Oregon State UniversityCorvallis, OR1$2.2 million0$0
Washington UniversitySaint Louis, MO1$2.2 million0$0
University of VirginiaCharlottesville, VA1$2.1 million0$0
Aavogen, Inc.Rockville, MD2$2 million0$0
Emmyon, Inc.Rochester, MN1$2 million0$0
Medical University of South CarolinaCharleston, SC2$1.9 million0$0
Emory UniversityAtlanta, GA2$1.9 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ1$1.7 million0$0
Kaiser Foundation Research InstituteOakland, CA1$1.7 million0$0
University of HoustonHouston, TX1$1.6 million0$0
University of South Carolina at ColumbiaColumbia, SC4$1.6 million0$0
New York University School of MedicineNew York, NY2$1.5 million0$0
Beth Israel Deaconess Medical CenterBoston, MA1$1.4 million0$0
University of Illinois at ChicagoChicago, IL1$1.4 million0$0
West Virginia University Research CorporationMorgantown, WV1$1.3 million0$0
University of ArkansasFayetteville, AR1$1.3 million0$0
Northwestern University at ChicagoChicago, IL3$1.3 million0$0
University of KentuckyLexington, KY2$1.2 million0$0
University of IowaIowa City, IA3$1.2 million0$0
Salk Institute for Biological StudiesLa Jolla, CA2$1.1 million0$0
Columbia University Health SciencesNew York, NY1$1.1 million0$0
Baylor College of MedicineHouston, TX1$1.1 million0$0
University of ArizonaTucson, AZ1$1 million0$0
Wake Forest University Health SciencesWinston-Salem, NC1$839,4660$0
William Marsh Rice UniversityHouston, TX1$780,5060$0
University of Nebraska Medical CenterOmaha, NE2$772,3450$0
Univ of Arkansas for Med ScisLittle Rock, AR1$749,9420$0
University of California, San DiegoLa Jolla, CA2$723,9380$0
University of ChicagoChicago, IL1$698,0760$0
University of CambridgeCambridge1$681,9750$0
Rehabilitation Institute of Chicago D/b/a Shirley Ryan AbilitylabChicago, IL1$677,1600$0
Cleveland Clinic Lerner Com-CwruCleveland, OH1$626,7250$0
University College LondonLondon1$624,2820$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA1$599,3040$0
Oakland UniversityRochester, MI1$590,9580$0
Hamilton Health Sciences CorporationHamilton1$570,5000$0
University of Vermont & ST Agric CollegeBurlington, VT2$521,6220$0
Sam Houston State UniversityHuntsville, TX1$512,3800$0
Oklahoma Medical Research FoundationOklahoma City, OK2$502,9630$0
Mayo Clinic RochesterRochester, MN1$472,1030$0
University of Missouri-ColumbiaColumbia, MO1$446,1720$0
University of TX MD Anderson Can CTRHouston, TX1$445,5000$0
Tufts Medical CenterBoston, MA1$430,4920$0
University of Massachusetts AmherstAmherst, MA1$421,8290$0
Scripps Research Institute, theLa Jolla, CA1$416,6670$0
University of California-BerkeleyBerkeley, CA1$413,6890$0
Sunnybrook Research InstituteToronto1$407,4970$0
University of WashingtonSeattle, WA1$366,3630$0
Beatson Institute for Cancer ResearchGlasgow1$357,4890$0
Baylor UniversityWaco, TX1$341,6000$0
Ridgeline Therapeutics, LLCHouston, TX1$322,4320$0
Broad Institute, Inc.Cambridge, MA1$298,1880$0
Myolex, Inc.Brookline, MA1$263,0520$0
Larix Bioscience, LLCSunnyvale, CA1$252,2820$0
University of North Carolina at CharlotteCharlotte, NC1$249,0000$0
RBHS -Cancer Institute of New JerseyNew Brunswick, NJ1$223,1820$0
University of GlasgowGlasgow1$209,8500$0
Massachusetts Institute of TechnologyCambridge, MA1$133,9550$0
Acepre, LLCColumbia, SC1$52,0000$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK1$44,1580$0
University of Michigan at Ann ArborAnn Arbor, MI1$35,8470$0
Federation of Amer Soc for Exper BiologyRockville, MD1$10,0000$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202569$31,536,2100$0
202475$31,519,7280$0
202368$30,315,5240$0
202265$29,146,2910$0
202154$24,491,9680$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)PAR-24-279NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 34 awards here
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)PAR-24-280NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 34 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.846November 23, 2026$375,000Same assistance listing 93.846 as 34 awards here
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0RFA-AR-26-006NIH93.846December 1, 2026Not listedSame assistance listing 93.846 as 34 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.846December 4, 2026Not listedSame assistance listing 93.846 as 34 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 34 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 34 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.846January 7, 2027Not listedSame assistance listing 93.846 as 34 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.846January 15, 2027$350,000Same assistance listing 93.846 as 34 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.846January 27, 2027$500,000Same assistance listing 93.846 as 34 awards here
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)PAR-25-141NIH93.846March 4, 2027Not listedSame assistance listing 93.846 as 34 awards here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin DiseasesPAR-27-109NIH93.846March 4, 2027$600,000Same assistance listing 93.846 as 34 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 34 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 34 awards here
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)PA-24-201NIH93.846April 18, 2027Not listedSame assistance listing 93.846 as 34 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIH93.846May 7, 2027Not listedSame assistance listing 93.846 as 34 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.846May 7, 2027Not listedSame assistance listing 93.846 as 34 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.