Data / Nonprofits / Tennessee / Knoxville / Health care
Health care nonprofits in Knoxville, TN: 69 registered with the IRS
69 health care nonprofits are registered with the IRS in Knoxville, TN, 68 of them 501(c)(3) charities; the 48 that report revenue took in $4.12 billion. The largest by revenue: University Health System Inc ($1.62 billion), Parkwest Medical Center ($469.8 million), Fort Sanders Regional Medical Center ($423.2 million).
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Every organization, largest by revenue first
| Organization | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|
| University Health System Inc | 501(c)(3) | 1999 | $1.62 billion | $1.32 billion | 2024-12 |
| Parkwest Medical Center | 501(c)(3) | 1990 | $469.8 million | $289.9 million | 2024-12 |
| Fort Sanders Regional Medical Center | 501(c)(3) | 2007 | $423.2 million | $249.5 million | 2024-12 |
| East Tennessee Childrens Hospital Association Inc | 501(c)(3) | 1952 | $413.8 million | $740.4 million | 2025-06 |
| Covenant Health | 501(c)(3) | 1996 | $235.7 million | $1.96 billion | 2024-12 |
| Methodist Medical Center | 501(c)(3) | 1960 | $184.4 million | $93.7 million | 2024-12 |
| Morristown Hamblen Hosp | 501(c)(3) | 1957 | $161.2 million | $109.8 million | 2024-12 |
| Leconte Medical Center | 501(c)(3) | 1981 | $160.4 million | $87.7 million | 2024-12 |
| Cumberland Medical Center Inc | 501(c)(3) | 1972 | $105.2 million | $82.7 million | 2024-12 |
| Vine International Inc | 501(c)(3) | 1994 | $58.2 million | $248,676 | 2024-12 |
| Fort Loudoun Medical Center | 501(c)(3) | 1990 | $53.8 million | $27.8 million | 2024-12 |
| Roane County Medical Center | 501(c)(3) | 2009 | $49.9 million | $49.1 million | 2024-12 |
| Hillcrest Healthcare Communities Inc | 501(c)(3) | 1962 | $43.3 million | $35.2 million | 2025-06 |
| Claiborne Medical Center | 501(c)(3) | 2014 | $37 million | $18.5 million | 2024-12 |
| Covenant Homecare | 501(c)(3) | 1997 | $25.4 million | $3.3 million | 2024-12 |
| Medic Inc | 501(c)(3) | 1981 | $22.6 million | $31 million | 2025-04 |
| Thompson Oncology Group Dba Covenant Health Oncology Group | 501(c)(3) | 1997 | $22.4 million | $9.8 million | 2024-12 |
| Interfaith Health Center Inc | 501(c)(3) | 1991 | $10 million | $15.5 million | 2025-06 |
| Special Spaces Inc | 501(c)(3) | 2005 | $2.8 million | $2.6 million | 2025-12 |
| East Tennessee Lions Eye Bank | 501(c)(3) | 1972 | $2.5 million | $4.1 million | 2025-06 |
| Covenant Health Foundation | 501(c)(3) | 1999 | $2 million | $18.4 million | 2024-12 |
| St Christopher Truckers Development & Relief Fund Inc | 501(c)(3) | 2008 | $1.9 million | $4.1 million | 2024-12 |
| Cerebral Palsy Center for Handicapped Adults Inc | 501(c)(3) | 2026 | $1.7 million | $524,345 | 2026-06 |
| Make A Wish Foundation of East Tennessee Inc | 501(c)(3) | 1988 | $1.5 million | $1.1 million | 2024-08 |
| Free Medical Clinic of America | 501(c)(3) | 2006 | $1.3 million | $2.2 million | 2025-06 |
| Sacred Ground Hospice House | 501(c)(3) | 2019 | $1.3 million | $2.7 million | 2024-12 |
| Ronald McDonald House Charities of Knoxville Tennessee Inc | 501(c)(3) | 1983 | $1.2 million | $14.7 million | 2025-12 |
| Hope Resource Center | 501(c)(3) | 1985 | $1 million | $937,240 | 2025-06 |
| Prevention Alliance of Tennessee | 501(c)(3) | 2021 | $903,487 | $404,245 | 2025-06 |
| Trinity Health Foundation of East Tennessee | 501(c)(3) | 2012 | $855,868 | $32.6 million | 2024-12 |
| U T Hospital Auxiliary Gift Shop Fund | 501(c)(3) | 1972 | $853,348 | $1.1 million | 2024-12 |
| Hellbender Harm Reduction | 501(c)(3) | 2023 | $709,498 | $70,832 | 2025-12 |
| New Direction Health Care Solutions | 501(c)(3) | 2021 | $639,262 | $206,729 | 2025-12 |
| Methodist Medical Center Foundation | 501(c)(3) | 1990 | $503,123 | $2.1 million | 2024-12 |
| A Step Ahead Foundation of East Tennessee Inc | 501(c)(3) | 2016 | $438,050 | $173,498 | 2025-06 |
| National Embryo Adoption Center | 501(c)(3) | 2006 | $419,229 | $458,279 | 2025-06 |
| Random Acts of Flowers | 501(c)(3) | 2009 | $409,065 | $481,591 | 2025-12 |
| Morristown-Hamblen Hospital | 501(c)(3) | 1998 | $300,197 | $2 million | 2024-12 |
| Breast Connect Inc | 501(c)(3) | 2015 | $182,116 | $194,085 | 2025-12 |
| The Dream Connection Inc | 501(c)(3) | 1986 | $108,977 | $441,476 | 2025-12 |
| Autism Breakthrough Foundation | 501(c)(3) | 2024 | $76,311 | $73,425 | 2025-06 |
| East Knox Free Medical Clinic Inc | 501(c)(3) | 2013 | $51,948 | $54,099 | 2025-12 |
| Proton Therapy Center LLC | 501(c)(3) | 2012 | $26,750 | $15,670 | 2025-12 |
| Soulbridge | 501(c)(3) | 2025 | $7,038 | $1,403 | 2025-12 |
| MTPC LLC | 501(c)(3) | 2015 | $3,363 | $46,488 | 2025-12 |
| American Association of Psychedelics | 501(c)(3) | 2022 | $2,110 | $2,613 | 2023-12 |
| Surgery On Sunday - Knoxville | 501(c)(3) | 2023 | $1,999 | $87,286 | 2025-12 |
| Provision Cares Foundation Inc | 501(c)(3) | 2012 | $128 | $2 million | 2025-12 |
| Alex Gardners Mother-Baby Nutrition Foundation | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| American Doctor of Medical Science Association | 501(c)(6) | 2019 | $0 | $0 | 2025-12 |
| Brooks Books | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Compassion in Action Corporation | 501(c)(3) | 2013 | $0 | $0 | 2024-12 |
| Dental Mission for Children Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Derrick Stone Safe Sleep | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Eddie Check | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Firefly Cancer Awareness and Care | 501(c)(3) | 2025 | $75,925 | 2025-12 | |
| Grace Health Corp | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Her Huddle | 501(c)(3) | 2026 | |||
| Inspiring Ubuntu Coalition Nonprofit Inc | 501(c)(3) | 2022 | $0 | $0 | 2026-03 |
| Kidz Team Inc | 501(c)(3) | 2008 | $0 | $0 | 2024-12 |
| Mildmay USA Inc | 501(c)(3) | 2026 | |||
| PCPT Lenexa LLC | 501(c)(3) | 2019 | $0 | $802,306 | 2025-12 |
| People Empowering People Project | 501(c)(3) | 2001 | $0 | $0 | 2025-12 |
| Relief Aid United Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Restoration Movement Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Second To None Mobility | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Smiles for Hope | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Smoky Mountain Lions Charities-Mobile Vision Lab | 501(c)(3) | 2015 | $0 | $0 | 2026-06 |
| Zimbabwe Medical Project | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
Other causes in Knoxville, TN
- Religion-related 301
- Education 279
- Human services 196
- Recreation and sports 147
- Arts, culture and humanities 136
- Philanthropy, voluntarism and grantmaking foundations 111
- Community improvement and capacity building 91
- Youth development 67
- Animal-related 44
- Mental health and crisis intervention 42
- Public and societal benefit 36
- Housing and shelter 35
- Environment 32
- International, foreign affairs and national security 32
- Mutual and membership benefit 26
- Food, agriculture and nutrition 25
- Diseases, disorders and medical disciplines 23
- Employment 18
- Crime and legal-related 16
- Medical research 15
- Civil rights, social action and advocacy 15
- Public safety, disaster preparedness and relief 14
- Science and technology 13
- Social science 5
Every nonprofit in Knoxville, TN · Health care nonprofits across the state · Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.