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Data / Nonprofits / South Dakota / Sioux Falls / Human services

Human services nonprofits in Sioux Falls, SD: 98 registered with the IRS

98 human services nonprofits are registered with the IRS in Sioux Falls, SD, 97 of them 501(c)(3) charities; the 48 that report revenue took in $1.22 billion. The largest by revenue: The Evangelical Lutheran Good Samaritan Society ($1.01 billion), South Dakota Achieve ($46.6 million), Childrens Home Society of South Dakota ($36.1 million).

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Every organization, largest by revenue first

OrganizationTypeSinceRevenueAssetsFiling
The Evangelical Lutheran Good Samaritan Society501(c)(3)1955$1.01 billion$970.4 million2024-12
South Dakota Achieve501(c)(3)1970$46.6 million$30.6 million2025-06
Childrens Home Society of South Dakota501(c)(3)1944$36.1 million$58.9 million2025-06
Dow Rummel Village501(c)(3)1968$26.2 million$71.7 million2025-04
Dakotabilities501(c)(3)1970$22.8 million$27.5 million2025-06
Childrens Home Foundation501(c)(3)1982$16.7 million$179.1 million2025-06
Boys and Girls Clubs of Sioux Empire501(c)(3)1988$11.3 million$11.2 million2025-12
Senior Citizens Services Inc501(c)(3)1968$7.1 million$19.6 million2025-12
Ronald McDonald House Charities of South Dakota Inc501(c)(3)1983$6.6 million$12.1 million2024-12
Asone Ministries501(c)(3)2015$5.6 million$3 million2025-12
Young Mens Christian Association501(c)(3)1942$4.9 million$7.5 million2025-08
Call To Freedom Inc501(c)(3)2016$3.2 million$3.9 million2024-12
Compassion Child Care501(c)(3)2014$3 million$2.1 million2024-12
Karl & Mary Jo Wegner Health Science Information Center501(c)(3)1998$1.7 million$9.2 million2025-06
Sioux Falls Ministry Center501(c)(3)2009$1.6 million$9.2 million2024-12
Furniture Mission501(c)(3)2003$1.2 million$3 million2024-12
Tallgrass Recovery & Sober Living Homes501(c)(3)2004$1.1 million$906,1922024-12
Giving Hope Inc501(c)(3)2017$920,674$247,7202025-12
Catholic Family Services501(c)(3)1946$917,346$1.1 million2025-06
South Dakota Parent Connection501(c)(3)1986$718,164$447,6912025-09
Emilys Hope Inc501(c)(3)2019$623,685$525,0672024-12
Sioux Falls Hope Coalition501(c)(3)2017$568,569$849,6432026-06
Shift Garage501(c)(3)2022$556,335$109,8942024-12
Lil Troopers Learning Center501(c)(3)1992$533,145$170,7702024-12
Community Outreach Corporation501(c)(3)1992$530,051$164,9492024-12
Center of Hope501(c)(3)2002$500,870$513,7372026-03
New Haven501(c)(3)1996$352,280$201,2242024-12
Justice Through Empowerment Network South Dakota Foundation501(c)(3)2022$340,942$14,9822024-06
East River Foster Parent Network501(c)(3)2012$307,461$168,4172025-12
Transformation Project Inc501(c)(3)2019$256,695$277,6662025-06
Judy Shaw Foundation Inc501(c)(3)2015$242,262$23,1352025-12
Sioux Residential Services Inc501(c)(3)1985$217,138$317,3492025-06
Project C A R Call-A-Ride501(c)(3)1989$216,810$259,8312025-12
Foster605501(c)(3)2024$182,544$53,6452025-12
Kids Against Hunger-Sioux Falls501(c)(3)2009$178,104$63,1202025-12
Evermore Blooms Co501(c)(3)2021$163,056$43,9472025-12
Cosmopolitan International501(c)(4)2025$158,975$557,4192025-06
Hawthorne Hall Inc501(c)(3)2002$135,095$344,8682025-12
Gathering Well501(c)(3)2020$130,486$87,4352024-12
Hands & Voices South Dakota501(c)(3)2020$125,237$138,0692025-12
Journey of Hope Inc501(c)(3)2021$124,002$59,7422025-12
Transforming Wealth501(c)(3)2021$118,934$98,1022024-12
Regency Cares501(c)(3)2018$87,685$207,9472025-12
South Dakota Association for the Deaf Foundation Inc501(c)(3)2017$70,518$1.1 million2025-12
Camp Gilbert Inc501(c)(3)2007$66,838$384,3072025-12
Community Action for Veterans501(c)(3)2022$66,352$10,7892025-06
South Dakota Association of the Deaf Inc501(c)(3)2003$55,498$54,0352025-06
Jakes Summer Classic501(c)(3)2020$30,165$1022025-12
A Hand 2 Hold Inc501(c)(3)2024$0$02025-12
A Voice for Children and Families501(c)(3)2008$0$02025-12
Agape United Foundation501(c)(3)2017$0$02024-12
Assist Foundation501(c)(3)2026
Bakat Orphan Care501(c)(3)2026
Bash 4 Cash LTD501(c)(3)2010$0$02024-12
Bor County Development Association501(c)(3)2026
Caring 4 Kidz Inc501(c)(3)2026
Childrens Advocacy Centers of South Dakota Inc501(c)(3)2025
Counseling and Crisis Center of Sou TH Dakota501(c)(3)2025
East River Hip Hop Church501(c)(3)2022$0$12023-12
Educated Mommy Inc501(c)(3)2012$0$02025-12
Emo Ya Mmbembe Mmbondo South Dakota501(c)(3)2025
Go Beyond Inc501(c)(3)2025
Homefront Warriors Foundation Inc501(c)(3)2017$0$02023-12
Inner Child Care Inc501(c)(3)2026$0$02025-12
JJS Kicks 4 Kids Inc501(c)(3)2024$0$02025-12
Kids Chance of South Dakota501(c)(3)2025$0$02021-12
Kirbys Closet501(c)(3)2019$0$02026-03
Lost Lives Matter Inc501(c)(3)2021$0$02025-12
Madylynnbrave501(c)(3)2024
Maeve Marie Foundation501(c)(3)2025$0$02025-04
Marions Song501(c)(3)2026
Mighty Hearts Charitable Fund NFP501(c)(3)2017$0$02025-12
Minnehaha County Family Violence Council501(c)(3)2000$0$02025-01
Moms Club501(c)(3)2001$0$02026-06
Move To Heal South Dakota501(c)(3)2025$0$02025-12
Moving Assistance Program501(c)(3)2007$0$02026-06
National Christian Association of P Rofessional Speakers501(c)(3)2025
Navigate Freedom Inc501(c)(3)2026
New Directions501(c)(3)2009$0$02025-12
One Leg B4 the Other501(c)(3)2025
Operation Meaningful Life Inc501(c)(3)2017$0$02024-12
Planning Life Inc501(c)(3)2004$0$02025-12
Quilting Allies501(c)(3)2023$1,0452025-12
SFS Foundation501(c)(3)2022$22,7732025-12
Sioux Falls Birthright Inc501(c)(3)2014
Sioux Falls Community Auto Repair501(c)(3)2022$0$02025-12
Socks From Sis501(c)(3)2026
Sons of Southfork Foundation501(c)(3)2015$0$02024-12
South Dakota Association of Residential Youth Care Providers501(c)(3)2008$0$02025-12
South Dakota Doulas501(c)(3)2023$0$02025-12
South Dakota Senior Games Association501(c)(3)1997$0$02025-12
Sowing Seeds for the Future FDTN501(c)(3)2000$0$02026-06
Step Up501(c)(3)2022$0$02023-12
Sunflower Haven501(c)(3)2022$0$02025-12
The Elevate Collective501(c)(3)2026
Themtjfoundation501(c)(3)2026
Trash the Stats501(c)(3)2024$0$02025-12
Voices Beyond Border501(c)(3)2025

Other causes in Sioux Falls, SD

Every nonprofit in Sioux Falls, SD · Human services nonprofits across the state · Nonprofits in every city of the state

Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.