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Data / Federal grants / RFA-HD-28-003

Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier

National Institutes of Health (Department of Health and Human Services) expects to post this opportunity around July 24, 2027, with applications due around October 20, 2027. It lists $3 million in total.

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Key facts

Opportunity number
RFA-HD-28-003
Status
Forecast
Posted
July 16, 2026
Closes
October 20, 2027
Total funding
$3,000,000
Cost sharing
Not required
Funding instrument
Grant
Category
Health
Assistance listing
93.865 Child Health and Human Development Extramural Research
Contact
Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · [email protected] · Please contact via e-mail

Who can apply

  • Public and State controlled institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • City or township governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Public housing authorities/Indian housing authorities
  • State governments
  • Native American tribal governments (Federally recognized)
  • Special district governments
  • Independent school districts
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • County governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What the agency says

The Eunice Kennedy Shriver National Institute of Child Health and Human Development seeks to advance its mission of supporting maternal, fetal, and child health by continuing to enhance the understanding of maternal, fetal, and child exposure to nutrients, metabolites, medications, supplements, microbiome-derived products, and environmental chemicals. This will be done by supporting a second phase of the Transporter Elucidation Network (TEN). This phase of the TEN will establish perinatal multi-barrier transport network frameworks to clarify how transporters and local biotransformation regulate these processes. Building on prior organ-focused models, methods, and datasets, this initiative will develop   standards, resources, models, and prototype multi-compartment approaches spanning maternal gut, placenta, lactating mammary epithelium, infant gut, and infant blood-brain barrier. The initiative is expected to support a mechanistic understanding of  transporter function, polarity, kinetics, and transformation capacity relevant to pregnancy, lactation, infant nutrition, pediatric pharmacology, and neurodevelopment. By emphasizing multi-barrier perinatal transporter frameworks this phase of the TEN will provide community resources for future integrated studies of perinatal exposure, risk, and intervention across interlinked maternal, fetal, and infant systems. It will also strengthen coordination among investigators, accelerate dissemination of tools, and advance human-based, developmentally relevant transporter research and workforce development. The grant authority for this is 42 U.S.C. § 241

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to Public colleges and universities · All grants open to Private colleges and universities · All grants open to For profit organizations other than small businesses · Everything closing in October 2027

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.