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Data / Federal grants / RFA-HG-27-013

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

National Institutes of Health (Department of Health and Human Services) is accepting applications until October 30, 2026. It lists awards of up to $500,000, 10 awards expected, $7.5 million in total.

SpecStream is the live web data engine for teams and agents. It reads every open and forecast federal opportunity on Grants.gov each morning, and this page is that reading. Describe your organization once and the grants that fit arrive in your sheet, CRM, Slack or agent as they are posted.

Key facts

Opportunity number
RFA-HG-27-013
Status
Posted, open
Posted
June 18, 2026
Closes
October 30, 2026
Award ceiling
$500,000
Award floor
$3
Expected awards
10
Total funding
$7,500,000
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Category
Health
Assistance listing
93.172 Human Genome Research
Contact
National Institutes of Health · [email protected] · 301-402-2541

Who can apply

  • For profit organizations other than small businesses
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Public and State controlled institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Small businesses
  • Special district governments
  • City or township governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Native American tribal governments (Federally recognized)
  • State governments
  • Independent school districts
  • County governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

What the agency says

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.

The notice on Grants.gov

Other open grants from the Department of Health and Human Services

All grants open to For profit organizations other than small businesses · All grants open to Public housing authorities/Indian housing authorities · All grants open to Tribal organizations · Everything closing in October 2026

Read from the Grants.gov API, last updated 2026-10-23. The agency's notice on Grants.gov is the official record; check it before you apply.