Data / Federal grants / October 2027

Federal grants closing in October 2027: 36 opportunities

Name: Federal grants closing in October 2027: 36 opportunities
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

36 accepting applications and 0 forecast, read from Grants.gov. The largest single award ceiling is $100 million. Most come from the Department of Health and Human Services (30), U.S. National Science Foundation (5), IV&V Test Agency (1).

SpecStream is the live web data engine for teams and agents. It reads every open and forecast federal opportunity on Grants.gov each morning, and this page is that reading. Describe your organization once and the grants that fit arrive in your sheet, CRM, Slack or agent as they are posted.

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Every opportunity, by deadline

Opportunity	Agency	Status	Closes	Award ceiling	Total funding	Record
Home Study and Post-Release Services for Unaccompanied Alien Children HHS-2026-ACF-ORR-ZU-0019	Administration for Children and Families - ORR	Open	Oct 1, 2027	$100,000,000	$555,000,000	grants.gov
BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed) RFA-NS-27-015	National Institutes of Health	Open	Oct 4, 2027		$10,000,000	grants.gov
Advanced Technological Education (ATE) 24-584	U.S. National Science Foundation	Open	Oct 7, 2027	$7,500,000	$74,000,000	grants.gov
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional) PAR-25-327	National Institutes of Health	Open	Oct 8, 2027			grants.gov
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed) PAR-25-248	National Institutes of Health	Open	Oct 8, 2027			grants.gov
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional) RFA-DC-25-002	National Institutes of Health	Open	Oct 12, 2027	$500,000	$500,000	grants.gov
Research Experiences for Teachers (RET) in Engineering and Computer Science 24-503	U.S. National Science Foundation	Open	Oct 13, 2027		$5,800,000	grants.gov
NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed) PAR-25-135	National Institutes of Health	Open	Oct 14, 2027			grants.gov
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required) PAR-25-313	National Institutes of Health	Open	Oct 14, 2027			grants.gov
Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required) PAR-25-179	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required) PAR-25-181	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) PAR-25-182	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required) PAR-25-183	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required) PAR-25-184	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) PAR-25-285	National Institutes of Health	Open	Oct 15, 2027			grants.gov
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required) PAR-25-180	National Institutes of Health	Open	Oct 15, 2027			grants.gov
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required) PAR-25-177	National Institutes of Health	Open	Oct 15, 2027			grants.gov
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional) PAR-25-120	National Institutes of Health	Open	Oct 15, 2027			grants.gov
NSF Astronomy and Astrophysics Postdoctoral Fellowships (AAPF) 22-621	U.S. National Science Foundation	Open	Oct 15, 2027		$990,000	grants.gov
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required) PAR-25-178	National Institutes of Health	Open	Oct 15, 2027			grants.gov
NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed) PAR-25-357	National Institutes of Health	Open	Oct 16, 2027			grants.gov
IVV-FT-OPP-10172026141319 IVV-FT-OPP-10172026141319	IV&V Test Agency	Open	Oct 17, 2027	$10	$10	grants.gov
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required) PAR-25-343	National Institutes of Health	Open	Oct 18, 2027			grants.gov
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) RFA-CA-27-019	National Institutes of Health	Open	Oct 19, 2027	$300,000	$2,400,000	grants.gov
Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR) 23-598	U.S. National Science Foundation	Open	Oct 19, 2027		$28,000,000	grants.gov
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) PAR-25-296	National Institutes of Health	Open	Oct 19, 2027	$650,000	$650,000	grants.gov
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed) PAR-25-060	National Institutes of Health	Open	Oct 20, 2027	$750,000	$750,000	grants.gov
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed) PAR-25-059	National Institutes of Health	Open	Oct 20, 2027	$750,000	$750,000	grants.gov
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed) PAR-25-225	National Institutes of Health	Open	Oct 20, 2027			grants.gov
Mathematical Sciences Postdoctoral Research Fellowships (MSPRF) 23-603	U.S. National Science Foundation	Open	Oct 20, 2027		$8,500,000	grants.gov
Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional) PAR-25-104	National Institutes of Health	Open	Oct 25, 2027			grants.gov
Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional) PAR-25-103	National Institutes of Health	Open	Oct 25, 2027			grants.gov
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional) PAR-25-352	National Institutes of Health	Open	Oct 25, 2027			grants.gov
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional) PAR-25-353	National Institutes of Health	Open	Oct 25, 2027			grants.gov
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) PAR-27-078	National Institutes of Health	Open	Oct 25, 2027	$375,000		grants.gov
Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed) RFA-MH-27-125	National Institutes of Health	Open	Oct 28, 2027			grants.gov

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Read from the Grants.gov API, last updated 2026-10-23. Free to reuse with credit to SpecStream under CC BY 4.0.