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Data / Federal grants / December 2027

Federal grants closing in December 2027: 8 opportunities

8 accepting applications and 0 forecast, read from Grants.gov. The largest single award ceiling is $350,000. Most come from the Department of Health and Human Services (7), Department of the Interior (1).

SpecStream is the live web data engine for teams and agents. It reads every open and forecast federal opportunity on Grants.gov each morning, and this page is that reading. Describe your organization once and the grants that fit arrive in your sheet, CRM, Slack or agent as they are posted.

Every opportunity, by deadline

OpportunityAgencyStatusClosesAward ceilingTotal fundingRecord
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
RFA-DA-26-055
National Institutes of HealthOpenDec 3, 2027grants.gov
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
RFA-DA-26-056
National Institutes of HealthOpenDec 3, 2027grants.gov
Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)
RFA-HL-26-019
National Institutes of HealthOpenDec 23, 2027grants.gov
Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)
RFA-HL-26-016
National Institutes of HealthOpenDec 23, 2027$350,000grants.gov
Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)
RFA-HL-26-020
National Institutes of HealthOpenDec 23, 2027grants.gov
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)
RFA-HL-26-017
National Institutes of HealthOpenDec 23, 2027grants.gov
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
RFA-HL-26-018
National Institutes of HealthOpenDec 23, 2027grants.gov
NPS Cooperative Ecosystems Studies Units (CESU) Master Cooperative Agreements
P23AS00132
National Park ServiceOpenDec 31, 2027grants.gov

Other months

Read from the Grants.gov API, last updated 2026-10-23. Free to reuse with credit to SpecStream under CC BY 4.0.