Skip to the page

Data / Research funding / Vector-Borne Diseases

Vector-Borne Diseases: 2,009 NIH awards ($2.4B) to 383 organizations

2,009 NIH awards ($2.4B) in the NIH spending category Vector-Borne Diseases, to 383 organizations, read 2026-11-04. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Topic
NIH spending category

Awards

The 500 largest of 2,009 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Vaccine and Treatment Evaluation UnitsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$22,981,366December 11, 2019November 30, 2026ROUPHAEL, NADINE GEORGESreporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
Vermont Biomedical Research Network-Vermont INBRENIHNational Institute of General Medical Sciences2021 to 2025$19,534,463September 30, 2001June 30, 2030FRANCKLYN, CHRISTOPHER Sreporter.nih.gov
University of Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,173,751December 11, 2019November 30, 2026WALD, ANNAreporter.nih.gov
Kaiser Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,173,633December 11, 2019November 30, 2026JACKSON, LISA Areporter.nih.gov
Protective immunity following dengue virus natural infections and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,429,941July 29, 2015July 31, 2030HARRIS, EVAreporter.nih.gov
Task A71: Comprehensive In Vivo Screening of Viral Pathogens of Pandemic PotentialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,745,278July 18, 2022July 17, 2025MORREY, JOHNreporter.nih.gov
Complement Mediated Remodeling in Pulmonary Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$11,355,302August 1, 2020June 30, 2026STENMARK, KURT R.reporter.nih.gov
Viral Immunity and VAccination (VIVA) Human Immunology Project Consortium (HIPC)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$9,862,919March 22, 2022February 28, 2027FERNANDEZ-SESMA, ANAreporter.nih.gov
University of Washington Arboviral Research Network (UWARN)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,499,281May 22, 2020June 5, 2025VAN VOORHIS, WESLEY Creporter.nih.gov
COBRE: Eukaryotic Pathogens Innovation Center (EPIC)NIHNational Institute of General Medical Sciences2022 to 2025$9,118,734July 15, 2022May 31, 2027MORRIS, JAMES CULVINreporter.nih.gov
Development of Therapeutic Candidates for Biodefense, Infections and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$8,743,439September 25, 2023June 24, 2024RAMSTEDT, URBANreporter.nih.gov
Task C16: Production and Development of Schistosomiasis Research ReagentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,933,000February 1, 2023January 31, 2026MENTINK-KANE, MARGARETreporter.nih.gov
Integrating innate and adaptive pathways in vaccine responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$7,762,589April 1, 2014March 31, 2024RAVETCH, JEFFREY VICTORreporter.nih.gov
Administrative Supplements for NIAID Regional Biocontainment Laboratories (RBL)NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$7,369,853September 23, 2021February 28, 2025ALEM, FARHANGreporter.nih.gov
EpiCenter for Emerging Infectious Disease IntelligenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$7,215,074July 13, 2020June 5, 2025JOHNSON, CHRISTINE KREUDERreporter.nih.gov
Emerging Infectious Diseases Research Center - East and Central AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,734,930June 1, 2020June 5, 2025NJENGA, M KARIUKIreporter.nih.gov
Lyme Disease: B cell epitope discovery and mechanisms of antibody protectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,722,146September 16, 2019September 15, 2024MANTIS, NICHOLAS J.reporter.nih.gov
Emerging infections: surveillance, epidemiology and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,690,286May 11, 2020June 5, 2025WANG, DAVIDreporter.nih.gov
West African Center for Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,658,566June 9, 2020June 5, 2025WEAVER, SCOTT Creporter.nih.gov
B Cell Epitope Discovery and Mechanisms of Antibody Protection: Responses to Dengue 4, Powassan, Chikungunya, and Venezuelan Equine Encephalitis VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,634,396September 16, 2023September 15, 2024FREMONT, DAVEDreporter.nih.gov
Facility and Building System Upgrades Support for the Howard T. Ricketts Biocontainment LaboratoryNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$6,593,067September 16, 2021February 28, 2025ADAMS, ERIN JUNEreporter.nih.gov
Realizing Effectiveness Across Continents with Hydroxyurea(REACH): A Phase I/II Pilot Study of Hyroxyurea for Children with Sickle Cell AnemiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$6,498,374August 1, 2017July 31, 2027WARE, RUSSELL Ereporter.nih.gov
Regional Biocontainment Laboratory (RBL) Upgrade for Colorado State University (CSU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$6,493,184September 23, 2021February 28, 2025DOBOS, KAREN MARIEreporter.nih.gov
Coordinating Research on Emerging Arboviral Threats Encoing the Neotropics (CREATE-NEO)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,472,246June 1, 2020June 5, 2025VASILAKIS, NIKOSreporter.nih.gov
Small-molecule activators of STING-signaling as novel adjuvants for flavivirus vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,461,817September 30, 2019September 29, 2024NELSON, JAYreporter.nih.gov
American and Asian Centers for Arboviral Research and Enhanced Surveillance (A2CARES)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,361,142July 20, 2020May 31, 2025HARRIS, EVAreporter.nih.gov
Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,330,175February 4, 2021January 31, 2026KAPPE, STEFAN HIreporter.nih.gov
Enhancing immunity to malaria in young children with effective chemopreventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,263,495July 1, 2025June 30, 2027JAGANNATHAN, PRASANNAreporter.nih.gov
Expanding the breadth, magnitude, and durability of PfSPZ vaccines by creating multi-strain vaccines, designer hybrid and genetically altered parasite vaccines and use of a unique adjuvant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,933,702April 8, 2021March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Computational models of naturally acquired immunity to falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,666,873April 1, 2020March 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,664,388April 1, 2022March 31, 2027TAYLOR, STEVE MYERreporter.nih.gov
Task C08: Maintenance of Black Fly (Simulium Vittatum IS-7) Immature and Adult StagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,602,994July 10, 2020December 31, 2024GRAY, ELMERreporter.nih.gov
Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,573,382September 1, 2021August 31, 2027NIGROVIC, LISE E.reporter.nih.gov
DON in Pediatric Cerebral Malaria: A Phase I / II Dose-Escalation Safety StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,567,850June 1, 2025May 31, 2027POSTELS, DOUGLASreporter.nih.gov
Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,526,401July 17, 2020June 5, 2025SAKUNTABHAI, ANAVAJreporter.nih.gov
Comparative systems biology of apicomplexan cell divisionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,447,470July 21, 2022June 30, 2027GUBBELS, MARC-JANreporter.nih.gov
Structure-Function Analysis of Mxra8 Interaction with AlphavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,414,348June 1, 2019July 31, 2029DIAMOND, MICHAEL Sreporter.nih.gov
DNA damage response and repair of a broken chromosomeNIHNational Institute of General Medical Sciences2021 to 2025$5,083,668June 1, 2018May 31, 2028HABER, JAMES Ereporter.nih.gov
Focal mass drug administration (fMDA) to reduce Plasmodium vivax transmission, a pragmatic cluster randomized controlled trial in PeruNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,036,878June 1, 2025May 31, 2027HSIANG, MICHELLE SANGreporter.nih.gov
Methotrexate treatment of Arthritis caused by Chikungunya virus (MARCH): A randomized controlled trial of methotrexate versus placebo in the treatment of chronic arthritis after chikungunya infectionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$5,036,160September 1, 2022August 31, 2027CHANG, AILEENreporter.nih.gov
Development of Therapeutic Candidates for Biodefense, Infections and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$5,018,496July 5, 2023May 31, 2028VOIGT, EMILYreporter.nih.gov
Quanitifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,011,286April 1, 2020March 31, 2026VAZQUEZ PROKOPEC, GONZALO MARTINreporter.nih.gov
Evaluation of an OMV-adjuvanted Chimeritrope Vaccine against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,961,891September 30, 2018September 29, 2023MORICI, LISAreporter.nih.gov
Living in the post-Zika world: Impact of interactions between dengue and Zika viruses on diagnostics, antibody dynamics, and correlates of disease riskNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,905,886July 13, 2021April 30, 2027HARRIS, EVAreporter.nih.gov
Large Scale T Cell Epitope Discovery:Global identification of epitopes derived from Zika (ZIKV), Chikungunya (CHIKV) viruses following natural infection and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,881,220September 30, 2019September 29, 2024MITCHELL, MAYAreporter.nih.gov
IgE antibody responses to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal) in murine and human atherosclerosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,866,733July 1, 2022June 30, 2027ERICKSON, LOREN Dreporter.nih.gov
Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,835,728December 1, 2020November 30, 2026ADAMS, JOHN Hreporter.nih.gov
Mechanisms of Cell Regulation and Manipulation by the Ubiquitin SystemNIHNational Institute of General Medical Sciences2021 to 2025$4,827,601June 1, 2020May 31, 2030HOCHSTRASSER, MARK Wreporter.nih.gov
Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,809,096April 15, 2020March 31, 2026DORSEY, MATTHEW Greporter.nih.gov
Development of Non-Human Primate Models to Assess Immunological Mechanisms and Antigenic Targets of Protective Sporozoite (SPZ) Vaccines and Establish Superior Efficacy of Next Generation SPZ vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,717,265April 1, 2021March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Mechanisms of innate immune dysfunction in SIV/malaria co-infection in pregnancyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$4,672,308September 24, 2021July 31, 2026MANUZAK, JENNIFERreporter.nih.gov
Heritable immunization of the white-footed mouse reservoir of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,657,626September 1, 2021August 31, 2026ESVELT, KEVINreporter.nih.gov
DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,647,135June 29, 2020May 31, 2026ANTIA, RUSTOM NOSHIRreporter.nih.gov
IgE antibodies to the mammalian oligosaccharide galactose-alpha-1, 3-galactose (alpha-gal): immunology, epidemiology and relevance to allergic and inflammatory diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,621,686July 1, 1984May 31, 2028PLATTS-MILLS, THOMAS A.reporter.nih.gov
Development of the INI-4001 and INI-2002 adjuvants within the context of a vaccine to prevent Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,583,801September 30, 2018September 29, 2024EVANS, JAYreporter.nih.gov
Long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in TanzaniavNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,537,676April 15, 2022March 31, 2027HSIANG, MICHELLE SANGreporter.nih.gov
Vaccine and Treatment Evaluation Units: Wolbachia-Infected Aedes aegypti Mosquitos in Reducing Arboviral Infection BrazilNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,402,306February 4, 2020November 30, 2027ROUPHAEL, NADINEreporter.nih.gov
Genome-wide CRISPR-Cas9 screens in insect cells to characterize insecticidal toxinsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,239,439June 15, 2022May 31, 2027DONG, MINreporter.nih.gov
Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug DiscoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,163,372November 15, 2020October 31, 2026STAKER, BART LEEreporter.nih.gov
Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,114,200February 10, 2022January 31, 2027WILDER, BRANDON KEITHreporter.nih.gov
New chemotherapy regimens and biomarkers for Chagas diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,104,835August 17, 2018July 31, 2025ALMEIDA, IGOR Creporter.nih.gov
Development of an oral liver-targeted prime-and-trap malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,104,491December 1, 2020November 30, 2026MURPHY, SEAN Creporter.nih.gov
Mitochondrial DNA of Normal and Mutant TrypanosomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,069,462September 1, 1978April 30, 2029STUART, KENNETH Dreporter.nih.gov
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of miceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,052,693April 14, 2021March 31, 2027FIKRIG, EROLreporter.nih.gov
Molecular elucidation of the Francisella tularensis virulence mechanismNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,049,782May 21, 2021April 30, 2027SCHUMACHER, MARIAreporter.nih.gov
Innovations in Functional B Cell Epitope Discovery for Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,031,164September 16, 2024September 15, 2026MANTIS, NICHOLASreporter.nih.gov
Defining functional humoral correlates of immunity to guide vaccine designNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,023,233November 24, 2020October 31, 2025BATISTA, FACUNDO DAMIANreporter.nih.gov
World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,949,988February 1, 2016March 24, 2025WEAVER, SCOTT Creporter.nih.gov
A systems immunology approach to evaluate malaria vaccine performance in endemic regions of KenyaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,921,000February 1, 2022January 31, 2027MOORMANN, ANN Mreporter.nih.gov
Next generation mosquito control through technology-driven trap development and artificial intelligence guided detection of mosquito breeding habitatsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,914,766September 17, 2021August 31, 2026NOLAN, MELISSA SUZANNEreporter.nih.gov
Selective Plasmodium proteasome inhibitors as novel multi-stage antimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,856,328September 1, 2019August 31, 2029LIN, GANGreporter.nih.gov
Optimization of novel phenotypic screening hits for treatment of MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,843,960April 1, 2021March 31, 2027PHILLIPS, MARGARET A.reporter.nih.gov
Task B24: Production of Well Characterized Challenge Material (WCCM) of High Priority Viral PathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,793,148February 29, 2024January 24, 2026TAMHANKAR, MANASIreporter.nih.gov
LDLRAD3 Receptor Interaction with Venezuelan Equine Encephalitis VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,787,436July 1, 2021June 30, 2027DIAMOND, MICHAEL Sreporter.nih.gov
Targeting the Genus Leishmania with Small MoleculesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,752,432March 24, 2021February 28, 2026SCHAUS, SCOTT EDWARDreporter.nih.gov
Skin microbiome contributions to the pathogenesis of cutaneous leishmaniasisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,738,057March 4, 2019April 30, 2029SCOTT, PHILLIPreporter.nih.gov
Validating the Flavivirus Envelope Protein as an Antiviral TargetNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,735,490March 1, 2020February 28, 2026YANG, PRISCILLA LI-NINGreporter.nih.gov
Lead Optimization of DHODH Inhibitors for MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,721,559January 1, 2013June 30, 2028PHILLIPS, MARGARET A.reporter.nih.gov
Enteric Pathogen Force of Infection among Children using SerologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,719,600July 1, 2021June 30, 2027ARNOLD, BENJAMIN Freporter.nih.gov
A Phase II Evaluation of the Safety and Protective Efficacy of the Live Attenuated Tetravalent Dengue Vaccine TetraVax-DV with Challenge by the Recombinant DENV-2 Virus in a Dengue Endemic PopulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$3,713,909August 21, 2019July 31, 2025KIRKPATRICK, BETH DIANEreporter.nih.gov
Structure-based design of broad flavivirus immunogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,710,975September 24, 2021August 31, 2026LAI, JONATHAN R.reporter.nih.gov
Functional B-cell Epitope Discovery for Arthropod-Borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,708,329September 16, 2024September 15, 2027reporter.nih.gov
Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,704,381March 19, 2021February 28, 2027AMARASINGHE, GAYA K.reporter.nih.gov
Research Program Award (R35 Clinical Trial Optional) - Dr. Robyn Klein NINDSNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,695,974May 1, 2021October 31, 2024CAIN, MATTHEW Dreporter.nih.gov
Malaria across borders: Measuring imported infections and contributions to local transmission in Uganda and ZimbabweNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,679,817June 16, 2021May 31, 2027RODRÍGUEZ-BARRAQUER, ISABELreporter.nih.gov
Neurodevelopment after postnatal Zika virus infection in infant macaquesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,679,627January 1, 2021November 30, 2026CHAHROUDI, ANN Mreporter.nih.gov
Severe Malaria And Risk to The Brain (SMART Brain)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,674,964April 15, 2008January 31, 2029JOHN, CHANDY C.reporter.nih.gov
Evaluation of Antibody Responses Elicited by Zika Vaccination in Flavivirus-naïve and -experienced IndividualsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,665,742April 13, 2021March 31, 2027KREBS, SHELLY Jreporter.nih.gov
PANDAA for universal, pan-lineage molecular detection of Crimean-Congo Hemorrhagic Fever virus.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,656,578March 24, 2021July 31, 2027MACLEOD, IAIN JAMESreporter.nih.gov
Fosinopril analogs for the treatment of human babesiosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,646,365April 21, 2021March 31, 2027BEN MAMOUN, CHOUKRIreporter.nih.gov
Development of a Replicon RNA-based Vaccine against Dengue and ZikaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,590,945June 1, 2021May 31, 2026SHRESTA, SUJANreporter.nih.gov
Optimizing the dose of tafenoquine for the radical cure of Plasmodium vivax malaria in Southeast AsiaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,588,034September 8, 2023August 31, 2028CHU, CINDY Sreporter.nih.gov
Sample-to-Answer, Rapid, Multiplexed and PCR-Free Diagnostics of Arboviral Diseases in Resource Limited SettingsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,579,220December 23, 2020November 30, 2026YANIK, AHMET ALIreporter.nih.gov
Adjuvant Development Program in the context of vaccines to protect against Y. pestis and Shigella.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,532,934September 30, 2018September 29, 2023ERNST, ROBERTreporter.nih.gov
The Tick Immune Response During Microbial InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,501,084December 1, 2015May 31, 2027PEDRA, JOAOreporter.nih.gov
Inducing durable, protective immune memory against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,488,192January 16, 2019December 31, 2023KAPPE, STEFAN HIreporter.nih.gov
Mechanisms of varied sensitivity of P. falciparum field isolates to the antimalarial drug pipelineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,469,861July 1, 2025June 30, 2028ROSENTHAL, PHILIP JONreporter.nih.gov
Rickettsia-host interface and multiple paths to invasionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,450,818June 15, 2016May 31, 2027RAHMAN, MOHAMMED SAYEEDURreporter.nih.gov
A Vaccine for Lymphatic Filariasis, LFGuard™NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,448,456March 1, 2019November 30, 2027CARTER, DARRICK ALBERTreporter.nih.gov
Evaluating the role of P53 pathways in malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,424,681February 1, 2021January 31, 2027TRAN, TUAN MANHreporter.nih.gov
Unraveling yellow fever 17D vaccine attenuation: The role of type I interferon and innate immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,421,854February 15, 2016July 31, 2027RICE, CHARLES Mreporter.nih.gov
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, DOSE-RANGING STUDY TO COMPARE THE SAFETY AND EFFICACY OF 3 DOSE LEVELS OF AV-1 IN HEALTHY ADULTS CHALLENGED WITH A CONTROLLED HUMAN INFECTION SNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$3,418,636August 23, 2023July 22, 2025DURBIN, ANNA PALMERreporter.nih.gov
Novel bi-specific immunotherapeutic against high-threat Gram-negative pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,410,042February 21, 2019January 31, 2025PERLIN, DAVID Sreporter.nih.gov
Chemogenomic Profiling of Plasmodium Falciparum Responses and ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,402,300February 10, 2015June 30, 2027ADAMS, JOHN Hreporter.nih.gov
Uncovering the parasite and host determinants of Plasmodium vivax hypnozoite formation and development using single cell sequencing and human liver-chimeric miceNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,399,010February 7, 2022January 31, 2027VAUGHAN, ASHLEY Mreporter.nih.gov
Optimization and Modes of Action of NEU-4438, a New Anti-trypanosome Lead DrugNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,385,142August 19, 2016March 31, 2027MENSA-WILMOT, KOJO A.reporter.nih.gov
Structure and function of the Plasmodium myosin XIV-actin glideosome.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,384,780May 11, 2017June 30, 2027TRYBUS, KATHLEEN Mreporter.nih.gov
Improving Response to Malaria Outbreaks in Amazon-Basin CountriesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,375,825September 1, 2025August 31, 2026PAN, WILLIAM KUANG-YAOreporter.nih.gov
Drug Discovery for Chagas DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,351,347May 9, 2019December 31, 2026BUCKNER, FREDERICK SIMMONSreporter.nih.gov
Innate Immune Activation in MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,341,812September 24, 2009February 28, 2025GOLENBOCK, DOUGLAS Treporter.nih.gov
Elucidating the role of TSR glycosylation in Plasmodium parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,339,688June 1, 2020May 31, 2026SWEARINGEN, KRISTIAN EDWARDreporter.nih.gov
The olfactory basis of locating nectar sugar sources in Aedes aegypti mosquitoesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,320,838March 5, 2021February 28, 2027RIFFELL, JEFFREY Areporter.nih.gov
Second-Generation Novel Liver Stage Active AntimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,320,110April 1, 2021March 31, 2027KELLY, JANE Xreporter.nih.gov
ncRNA: structure, function and inhibitionNIHNational Institute of General Medical Sciences2021 to 2025$3,317,990April 1, 2018May 31, 2028VARANI, GABRIELEreporter.nih.gov
Microbial Determinants of Excessive Inflammation and Severe Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$3,315,179September 19, 2025August 31, 2029STRLE, KLEMENreporter.nih.gov
Defining the resistome in P. falciparum: evolution and mechanismNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,309,597November 2, 2022October 31, 2027WINZELER, ELIZABETH Areporter.nih.gov
Trypanosome Transmission Biology in TsetseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,303,729December 17, 2021November 30, 2026AKSOY, SERAPreporter.nih.gov
The roles of ceramide and its derivatives in A. phagocytophilum pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,301,707June 6, 2018May 31, 2028CARLYON, JASON Areporter.nih.gov
Small molecule-induced degradation of dengue proteins as an antiviral strategyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,293,894July 23, 2020June 30, 2025YANG, PRISCILLA LI-NINGreporter.nih.gov
B cell Epitope Discovery and Mechanisms of Antibody Protection for Enterovirus and Bunyavirus Entry ProteinsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,291,808September 16, 2024September 15, 2026reporter.nih.gov
A structured transcriptional switching network that coordinates antigenic variation by malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,290,341September 22, 2021August 31, 2027DEITSCH, KIRK Wreporter.nih.gov
Malaria parasite determinants of host cell tropismNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,286,067July 1, 2022June 30, 2027DURAISINGH, MANOJ Treporter.nih.gov
Once Bitten: Acquisition of Malaria Adaptive Immunity (OBAMA - Immunity)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,285,014July 1, 2025June 30, 2028PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Treating Brain Swelling in Pediatric Cerebral MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,271,417December 12, 2016November 30, 2023TAYLOR, TERRIE ELLENreporter.nih.gov
Pathogenic low affinity CD8 T cells in malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,264,359September 17, 2021August 31, 2026LAMB, TRACEY JANEreporter.nih.gov
Vaccine-mediated cross-alphavirus protection for a live attenuated FDA licensed chikungunya virus vaccineNIHNational Institute of Allergy and Infectious Diseases2025$3,248,576July 25, 2025June 30, 2029COFFEY, LARK Lreporter.nih.gov
Human Monoclonal Antibodies for Encephalitic AlphavirusesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,248,015July 20, 2022June 30, 2027CROWE, JAMES Ereporter.nih.gov
A novel Lyme disease vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,240,479June 7, 2022May 31, 2027FIKRIG, EROLreporter.nih.gov
Spatial Targeting and Adaptive Vector Control for Residual Transmission and Malaria Elimination in Urban African SettingsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,239,370June 9, 2021May 31, 2027SMITH, DAVID L.reporter.nih.gov
Mechanisms and consequences of extrafollicular B cell activation during malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,235,595September 24, 2021August 31, 2027BUTLER, NOAH SULLIVANreporter.nih.gov
Gut Microbiota Modulation of Chikungunya Virus Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,216,725April 1, 2021March 31, 2027DIAMOND, MICHAEL Sreporter.nih.gov
Drivers of strain-specific and strain-transcendent antimalarial immunity in childhoodNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,209,021June 17, 2020May 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Development and Field Testing of a Novel Reservoir Targeted Antibiotic Against Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,201,446May 15, 2020April 30, 2026HU, LINDEN Treporter.nih.gov
Task B08: Development and Use of a Non-Human Primate Model of SARS-CoV-2 InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,192,083September 21, 2020June 14, 2023THOMPSON, KARENreporter.nih.gov
Impact of gene-drive systems for population modification on malaria vector mosquitoesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,173,474June 9, 2023May 31, 2026JAMES, ANTHONY A.reporter.nih.gov
Rational development of a vaccine against tick-borne rickettsiosesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,166,318August 1, 2022July 31, 2027FANG, RONG MEGANreporter.nih.gov
Transmission dynamics and fitness of reemerging St. Louis encephalitis virus in mosquito vectors and West Nile virus naïve and immune avian reservoirsNIHNational Institute of Allergy and Infectious Diseases2025$3,161,373July 22, 2025June 30, 2029COFFEY, LARK Lreporter.nih.gov
Mechanisms Of The Unusual Cytokinesis In TrypanosomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,158,051June 6, 2013May 31, 2027LI, ZIYINreporter.nih.gov
The role of γδ T cells in fetal and infant immune defense against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,151,506March 15, 2011May 31, 2027FEENEY, MARGARET Ereporter.nih.gov
Analysis of a novel Crimean-Congo hemorrhagic fever vaccine and its mechanism of protection in rodent modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,145,040August 25, 2022July 31, 2026SCHNELL, MATTHIAS JOHANNESreporter.nih.gov
Plasmodium Protein Kinase Focused Antimalarials DiscoveryNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,144,589July 11, 2022June 30, 2027CHAKRABARTI, DEBOPAMreporter.nih.gov
Maternal Antibody-Mediated Enhancement of Dengue PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,138,902March 5, 2021February 28, 2026SHRESTA, SUJANreporter.nih.gov
Mechanisms of Protection and Durability for a Live Attenuated Tetravalent Dengue VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,135,970February 1, 2019January 31, 2029DIEHL, SEAN A.reporter.nih.gov
B-Cell Epitope Discovery and Mechanisms of Antibody Protection for ZIKV, MARV, VEEV Envelope ProteinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,133,973September 16, 2019September 15, 2024DORANZ, BENJAMINreporter.nih.gov
Iron independent role for yersiniabactin in Yersinia pestisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,128,137June 4, 2021May 31, 2027LAWRENZ, MATTHEW Breporter.nih.gov
Genomic consequences of schistosome hybridizationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,122,895September 27, 2021August 31, 2027ANDERSON, TIM Jreporter.nih.gov
Redefining thermal suitability for urban malaria transmission in the context of humidityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,108,969September 14, 2020August 31, 2027MURDOCK, COURTNEYreporter.nih.gov
Mechanisms of myocarditis and progressive cardiac fibrosis in chronic Trypanosoma cruzi infection.NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,103,804March 18, 2022February 28, 2027JONES, KATHRYN MARIEreporter.nih.gov
Immunological characterization of rationally-designed vaccines against plague in mice and non-human primate modelsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,082,735February 1, 2021July 31, 2026CHOPRA, ASHOK Kreporter.nih.gov
Novel Therapeutics to Target Parasite Cytochrome bc1NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,077,845July 15, 2012June 30, 2027RISCOE, MICHAEL KEVINreporter.nih.gov
Molecular basis of antimalarial drug resistance in Plasmodium vivaxNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,064,807March 18, 2022February 28, 2027DURAISINGH, MANOJ Treporter.nih.gov
Trypanocidal Agents that Kill Multiple Stages of the Trypanosoma cruzi Life CycleNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,050,000July 20, 2020March 31, 2027MCDONNELL, MARK Ereporter.nih.gov
Point-of-care diagnostic test for T. cruzi (Chagas) infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,050,000August 7, 2018March 31, 2027LEVIN, ANDREW E.reporter.nih.gov
Systems biological assessment of vaccination-induced protective immunity in African childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,984February 1, 2022January 31, 2027PULENDRAN, BALIreporter.nih.gov
Innate Immune Mechanisms Governing Subclinical Malaria in ChildrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,030,131September 1, 2022August 31, 2026KAZURA, JAMES WALTERreporter.nih.gov
Early neural predictors and neuropathogenesis of sensorimotor neurodevelopmental deficits in macaque infants exposed to Zika virus in uteroNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,025,789June 1, 2020May 31, 2026MOHR, EMMA Lreporter.nih.gov
Novel Antimalarials from FungiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,025,049May 18, 2020April 30, 2026CHAKRABARTI, DEBOPAMreporter.nih.gov
A peptide-based point-of-care vertical flow assay for the rapid diagnosis of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,023,104June 24, 2020June 30, 2025ARNABOLDI, PAUL MICHAELreporter.nih.gov
Understanding the mechanisms of antibody-mediated transcytosis of ZIKV within the placentaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,021,123June 11, 2020May 31, 2026SUTHAR, MEHUL SHAMALreporter.nih.gov
Deciphering the Role of Chemokine Receptor CCR5 in Maternal Flavivirus InfectionsNIHNational Institute of Allergy and Infectious Diseases2025$3,021,038September 2, 2025August 31, 2029LIM, JEAN KYOUreporter.nih.gov
A Unique Automated Bioreactor for Rearing Aseptic Mosquitoes from Larvae to Adults to Support Manufacture of Sanaria PfSPZ ProductsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000July 18, 2018March 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
Development of a ZIKA viral pseudoinfectious virus as ZIKA vaccine candidate (STTR Phase II)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000August 1, 2017March 31, 2026PANG, XIAOWUreporter.nih.gov
Long Lasting Organic Semiochemical Formulation to Effectively Manage Blood Sucking Diptera.NIHNational Institute of Allergy and Infectious Diseases2022 to 2024$3,000,000July 12, 2017January 31, 2026MAFRA-NETO, AGENORreporter.nih.gov
DEVELOPMENT OF COVALENTLY BOUND HYALURONIC ACID AS AN ADJUVANT FOR MULTIVALENT LYME DISEASE VACCINENIHNational Institute of Allergy and Infectious Diseases2024$2,999,999September 30, 2024September 29, 2027PETILLO, PETER Areporter.nih.gov
Cofactor metabolism and mitochondrial function in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,772August 18, 2023July 31, 2027PRIGGE, SEAN TAYLORreporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,001April 21, 2020March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Recombinant West Nile Virus Vaccine Adjuvanted with SLA-LSQ Optimize Formulation of VSA AdjuvantNIHNational Institute of Allergy and Infectious Diseases2022$2,997,218July 5, 2022July 5, 2025CLEMENTS, DAVIDreporter.nih.gov
Integrin activator-adjuvanted DNA vaccine against Trypanosoma cruzi infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,995,034July 14, 2022June 30, 2026MARATHI, UPENDRAreporter.nih.gov
Progressing PfSPZ vaccines for malaria to licensure and commercializationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,994,338April 14, 2023March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Live-attenuated Rift Valley fever vaccines: comparative mechanisms of trans-placental transmission and vaccine efficacy for developing fetusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,993,583March 1, 2020February 28, 2027HARTMAN, AMY Lreporter.nih.gov
Intranasal Vaccine Against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,988,409July 12, 2022June 30, 2026GOMES-SOLECKI, MARIAreporter.nih.gov
Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasitesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,972,178March 4, 2022February 28, 2027DVORIN, JEFFREY Dreporter.nih.gov
Mechanisms of SFG Rickettsia-Host InteractionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,971,223August 12, 2021July 31, 2030LAMASON, REBECCA Lreporter.nih.gov
Optimization of antimalarials targeting multiple life stages of the parasiteNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,967,032August 4, 2021July 31, 2027CARLIER, PAUL Rreporter.nih.gov
Learning from the Ebola success: Can a mAb also save lives after yellow fever infection?NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,966,587August 6, 2021July 31, 2025WATKINS, DAVID Ireporter.nih.gov
Chikungunya Recombinant Subunit VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,965,282July 22, 2016September 30, 2025CLEMENTS, DAVID Ereporter.nih.gov
Advancing Fast-acting Antimalarials that Disrupt Na+ Homeostasis in ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,964,364August 12, 2020July 31, 2026VAIDYA, AKHIL Breporter.nih.gov
Pharmacological insights into antimalarial exposure, clinical outcomes, and drug resistance in AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,963,157February 10, 2015April 30, 2026ROSENTHAL, PHILIP JONreporter.nih.gov
Self-eliminating strategy to control gene driveNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,962,580June 25, 2020May 31, 2026ADELMAN, ZACH N.reporter.nih.gov
Artemisinin Resistance in Africa: its emergence and evolution in RwandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,954,668August 5, 2021July 31, 2025BAILEY, JEFFREY A.reporter.nih.gov
Determining the interactions between mosquito oogenesis and Plasmodium falciparum survival and transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,950,744June 11, 2020May 9, 2025CATTERUCCIA, FLAMINIAreporter.nih.gov
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1NIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,948,061January 21, 2019July 31, 2025FIKRIG, EROLreporter.nih.gov
Anchimerically Activatable Anti-Zika/Dengue ProTidesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,946,770August 1, 2021July 31, 2026WAGNER, CARSTON R.reporter.nih.gov
Mechanisms of Rickettsia invasion, intracellular survival, and actin-based motilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,937,177September 1, 2014August 31, 2028WELCH, MATTHEW Dreporter.nih.gov
A glycolipid adjuvant to promote dose sparing, accelerate immunization schedules and extend durability of high-level protection with an attenuated, live sporozoite malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,935,817July 1, 2016June 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
A universal malaria T cell vaccine based on HLA-E presentationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,934,908May 20, 2022April 30, 2027WILDER, BRANDON KEITHreporter.nih.gov
Biomarker-Based Test of Cure for Chagas DiseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,934,864July 16, 2019August 31, 2027LEVIN, ANDREW E.reporter.nih.gov
Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,925,300May 17, 2018June 30, 2025KHUONG, NHIreporter.nih.gov
Automating mosquito microdissection for a malaria PfSPZ vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,924,306June 20, 2017April 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Activation, Phenotype and Function of CD4 T Cells in Schistosoma-Pulmonary HypertensionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,921,561December 15, 2016August 31, 2027GRAHAM, BRIAN BARKLEYreporter.nih.gov
Genomic and geospatial analyses of malaria parasite migration to inform eliminationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,915,635March 1, 2020February 28, 2026HARRISON, SHANNON TAKALAreporter.nih.gov
Childhood Outcome After In Utero ZIKV ExposureNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,915,429September 10, 2020June 30, 2025MULKEY, SARAH BETHreporter.nih.gov
Leveraging PfCRT Structure to Discern Function and Predict Emergence of Drug-Resistant MalariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,908,665July 1, 2019November 30, 2029MANCIA, FILIPPOreporter.nih.gov
Comprehensive characterization of ancestral populations of the vector Aedes aegypti on Indian Ocean islandsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,908,225July 6, 2021December 31, 2026POWELL, JEFFREY Rreporter.nih.gov
The synergistic contributions of EBV and malaria to the etiology of Burkitt lymphomaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,895,508December 12, 2019January 31, 2025SAMAYOA REYES, GABRIELA Mreporter.nih.gov
PreQuine Platform. A novel point of care device for the diagnosis andmonitoring of Glucose-6-Phosphate Dehydrogenase (G6PD)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,893,164February 8, 2017August 31, 2025HARPER, ROBERTreporter.nih.gov
Structure based design of dengue subunit vaccines for inducing protective but not disease enhancing antibodiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,892,736April 21, 2022March 31, 2027DESILVA, ARAVINDA M.reporter.nih.gov
The roles of Lyme spirochete adhesins in hematogenous disseminationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,886,252February 10, 2022January 31, 2027COBURN, JENIFER Lreporter.nih.gov
Malaria transmission blocking through mosquito contact with treated surfacesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,877,675February 4, 2020January 31, 2026CATTERUCCIA, FLAMINIAreporter.nih.gov
Structure-Function Relationships in the Spirochetal Flagellar MotorNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,865,323February 15, 2010May 31, 2027LIU, JUNreporter.nih.gov
High accuracy automated tick classification using computer visionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,863,916April 18, 2022September 30, 2026GOODWIN, AUTUMNreporter.nih.gov
Dual artemisinin action combats resistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,862,998March 18, 2021February 28, 2027SULLIVAN, DAVID JOSEPHreporter.nih.gov
Preclinical Development of a Crimean-Congo Hemorrhagic Fever Virus VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,862,279July 15, 2020June 30, 2026GEISBERT, THOMAS WILLIAMreporter.nih.gov
Gut microbiota and human malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,860,358July 1, 2020June 30, 2026SCHMIDT, NATHANreporter.nih.gov
JAK-STAT Control of Zika Virus-Induced Fetal InjuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,840,817July 1, 2019June 30, 2025ADAMS WALDORF, KRISTINA M.reporter.nih.gov
PANDAA for universal, pan-lineage molecular detection of filoviruses to enable rapid epidemic response.NIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,838,974August 1, 2022July 31, 2025MACLEOD, IAIN JAMESreporter.nih.gov
Multivalent Tick-Microbe targeted Lyme disease vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,836,037July 20, 2020June 30, 2027PAL, UTPALreporter.nih.gov
Genetic architecture of host response to tickborne disease in Peromyscus leucopusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,831,395September 17, 2020August 31, 2025LONG, ANTHONY DOUGLASreporter.nih.gov
Defining targets of protective immunity to vivax malaria using human monoclonal antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,825,320March 24, 2020February 28, 2026KING, CHRISTOPHER Lreporter.nih.gov
Relapsing malaria in Africa: mechanisms for persistence amid falciparum declineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,825,021July 25, 2022June 30, 2027JULIANO, JONATHAN Jreporter.nih.gov
A Randomized Phase I Clinical Trial of HydroVax-YFV, a Novel Inativated Yellow Fever VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,822,362July 1, 2019June 30, 2025AMANNA, IAN JAMESreporter.nih.gov
Importation and transmission of malaria in Zanzibar: a case study for eliminationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,816,019August 1, 2021July 31, 2025JULIANO, JONATHAN Jreporter.nih.gov
An integrated approach to understand and diagnose congenital Chagas diseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,811,708June 1, 2025May 31, 2027BOWMAN, NATALIE MCCARTERreporter.nih.gov
Mechanisms of endothelial dysfunction in cerebral malaria and barrier restorative pathwaysNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,808,572September 23, 2020August 31, 2025SMITH, JOSEPH Dreporter.nih.gov
Accelerating Malaria Vaccines with a Custom Preclinical Humanized Mouse Model PlatformNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,803,324March 1, 2022February 28, 2027BATISTA, FACUNDO DAMIANreporter.nih.gov
Developing a multi-component vaccine harnessing potent antibody and cellular responses against the blood-stage of Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,802,178May 1, 2022April 30, 2027SRINIVASAN, PRAKASHreporter.nih.gov
After the flood: Optimal strategies to prevent malaria epidemics caused by severe floodingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,800,889September 1, 2025August 31, 2028BOYCE, ROSS MATHEWreporter.nih.gov
Chromatin Biology of the African TrypanosomeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,795,048June 1, 2025May 31, 2027DEBLER, ERIKreporter.nih.gov
Developing capsid-importin alpha inhibitors for the treatment of VEEV infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,793,911September 15, 2020August 31, 2025PAIGE, MIKELLreporter.nih.gov
Discovery of long-acting, chemoprotective antimalarial compoundsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,791,259March 25, 2020February 28, 2026WINZELER, ELIZABETH Areporter.nih.gov
Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine CandidatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,788,646August 1, 2025July 31, 2027BEI, AMY KRISTINEreporter.nih.gov
Mapping Drug Resistance Genes in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,782,422September 1, 2000November 30, 2027ANDERSON, TIM Jreporter.nih.gov
Collective Responses to Malaria VaccinationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,779,001February 9, 2022January 31, 2027STUART, KENNETH Dreporter.nih.gov
Yersinia Outer-Membrane-Vesicle Vaccines Against Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,776,243January 25, 2022December 31, 2026SUN, WEIreporter.nih.gov
Polymeric matrix loaded with tick repellent or toxic compositions for incorporation into fabrics or for granular dispersalNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,775,723September 23, 2022August 31, 2025BANFIELD, MICHAEL GILBERTreporter.nih.gov
MEDSCAN: Mobile Enabled Diagnostics for Schistosomiasis Control AnalyticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,773,593July 9, 2021June 30, 2027SCHERR, THOMAS Freporter.nih.gov
Hybrid ELISA: Simple and specific one-tier assay for Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,764,666March 6, 2019August 31, 2027LEVIN, ANDREW E.reporter.nih.gov
Genetics and genomics of schistosome resistance in snailsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,761,828June 17, 2022May 31, 2027ZHANG, SI-MINGreporter.nih.gov
Molecular basis of immunity to tick-borne rickettsiosesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,758,756September 1, 2021August 31, 2027KIM, HWAN KEUNreporter.nih.gov
Host and parasite factors influencing P. vivax RBC invasion and asexual developmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,748,338June 1, 2025May 31, 2027SERRE, DAVIDreporter.nih.gov
Harnessing the Malarial Immunity Omics Landscape in Vaccinated and Unvaccinated Children for Improved Therapeutic StrategiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,743,704July 1, 2025June 30, 2029PERKINS, DOUGLAS JAYreporter.nih.gov
Neural and molecular rules of mosquito olfactory rhythmsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,742,882June 1, 2021May 31, 2027VINAUGER, CLEMENTreporter.nih.gov
Proline homeostasis: a novel mediator of drug tolerance in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,742,796April 1, 2020March 31, 2025MAZITSCHEK, RALPHreporter.nih.gov
Opsins and TRP channels controlling sensation and behavior in Aedes aeygptiNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,737,710September 24, 2021August 31, 2026MONTELL, CRAIGreporter.nih.gov
Targeting Cyclic Dinucleotide Signaling Pathways to Interrupt the Nature Cycle of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,734,150June 9, 2020May 31, 2026YANG, X. FRANKreporter.nih.gov
New Targets for Reproductive Control of Mosquito VectorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,733,145June 1, 2011July 31, 2027HARRINGTON, LAURA Creporter.nih.gov
Defining conserved epitopes on polymorphic malaria antigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,726,813February 19, 2021January 31, 2027BUNNIK, EVELIEN MARGARETHAreporter.nih.gov
Dengue-Zika: Correlates of Cross-Protection in Non-Human PrimatesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,724,960January 9, 2020December 31, 2025SARIOL, CARLOS Areporter.nih.gov
West Nile virus control through mosquitocidal avian bloodmealsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,710,198September 22, 2020August 31, 2026FOY, BRIAN DAVIDreporter.nih.gov
Host Metabolic Biosignatures for the Diagnosis of Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,695,774June 19, 2019May 31, 2025BELISLE, JOHN Treporter.nih.gov
Regulatory Pathways in Borrelial PathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,694,240August 5, 2022July 31, 2027SKARE, JON Treporter.nih.gov
Metabolic basis of mosquito-endosymbiont-virus interactionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,685,944March 1, 2020February 28, 2026PERERA, RUSHIKAreporter.nih.gov
Comprehensively Defining the Novel Alphaviral Capsid Protein / IRAK1 InteractionNIHNational Institute of Allergy and Infectious Diseases2025$2,681,840September 4, 2025August 31, 2029SOKOLOSKI, KEVIN JOSEPHreporter.nih.gov
COVID Transmission and Morbidity in Malawi (COVID-TMM)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,666,340April 1, 2025March 31, 2027VALIM, CLARISSAreporter.nih.gov
Molecular pathways affected by drugs that disrupt Na+ and lipid homeostasis in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,652,142May 5, 2017December 31, 2027VAIDYA, AKHIL Breporter.nih.gov
Lead optimization and target identification of drugs targeting hypnozoitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,647,674August 7, 2020July 31, 2025KYLE, DENNIS Ereporter.nih.gov
Host factors and viral determinants mediating flavivirus NS1 tissue-specific endothelial dysfunction and vascular leakNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,639,200April 18, 2022March 31, 2027HARRIS, EVAreporter.nih.gov
The molecular and cellular basis of short-range host cue sensing in mosquito vectorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,636,373September 21, 2020August 31, 2025GARRITY, PAULreporter.nih.gov
Resistance of Malaria Parasites to Artemisinin-Based Combination Therapies in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,627,211August 1, 2008August 31, 2025ROSENTHAL, PHILIP JONreporter.nih.gov
Understanding alpha-gal red meat allergyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,615,501September 24, 2018January 31, 2029COMMINS, SCOTT PALMERreporter.nih.gov
DEVELOPMENT OF A BROAD-SPECTRUM THERAPEUTICNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,609,829September 23, 2016September 30, 2022RAMSTEDT, URBANreporter.nih.gov
Baseline host and environmental factors that impact pre-erythrocytic malaria vaccine (hypo)responsiveness in endemic regionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,600,040March 8, 2022February 28, 2027YAZDANBAKHSH, MARIAreporter.nih.gov
Population genomics and new tools for the endgame of onchocerciasis elimination in AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,588,507December 1, 2019November 30, 2025MITREVA, MAKEDONKAreporter.nih.gov
Global Research Endeavors to Advance Treatment of Neurological Disorders in Africa (GREAT Neurology)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,561,391May 1, 2021April 30, 2029BIRBECK, GRETCHEN L.reporter.nih.gov
Tick Saliva and Pathogen TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,544,342May 9, 2018June 30, 2029PEDRA, JOAOreporter.nih.gov
Defining the Role of PfCRT and PfMDR1 as Pleiotropic Mediators of Plasmodium falciparum Multidrug ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,538,591August 1, 2001January 31, 2028FIDOCK, DAVID Areporter.nih.gov
Assessing desiccation tolerance's impact on Aedes aegypti midgut infectionNIHNational Institute of Allergy and Infectious Diseases2025$2,536,503September 8, 2025August 31, 2029DICKSON, LAURA Breporter.nih.gov
Vaccines for Prevention of RG3 and RG4 Emerging Tickborne Viral DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,523,497August 20, 2021July 31, 2026VERARDI, PAULO Hreporter.nih.gov
Novel Multiple-Stage Active AntimalarialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,520,964June 14, 2019August 31, 2030KANCHARLA, PAPIREDDYreporter.nih.gov
Implicating a previously unknown Dectin1-RIPK2-CARD9 signaling in providing resistance against Leishmania major infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,516,676March 24, 2021February 28, 2027GURUNG, PRAJWALreporter.nih.gov
Enhancing dengue virus genomic surveillance to uncover circulating genetic diversityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,514,500September 21, 2022August 31, 2027GRUBAUGH, NATHAN DALEreporter.nih.gov
Membrane Protein Effectors of Pathogen Interactions With HostNIHNational Institute of General Medical Sciences2022 to 2025$2,510,135June 1, 2016May 31, 2026MARASSI, FRANCESCA Mreporter.nih.gov
Opsins as a new class of evolutionarily conserved taste receptorsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,503,868June 1, 2017May 31, 2027MONTELL, CRAIGreporter.nih.gov
Optimization of Antischistosomal ChemotypesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,501,475February 1, 2015March 31, 2026VENNERSTROM, JONATHAN Lreporter.nih.gov
A GLYCOLIPID ADJUVANT 7DW8-5 FOR MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,501,040September 30, 2023September 29, 2028TSUJI, MORIYAreporter.nih.gov
Development of vaccines targeting a tick-borne phlebovirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,499,856July 10, 2020June 30, 2025BATES, PAULreporter.nih.gov
A clear view of encephalitis: a single cell approach to determine the basis of flaviviral pathogenesis in the central nervous systemNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,486,737January 21, 2022December 31, 2026RICE, CHARLES Mreporter.nih.gov
Zika virus nonstructural protein 5 inhibition of interferon signalingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,477,738August 21, 2023July 31, 2027EVANS, MATTHEW Jreporter.nih.gov
Translation of evolution-guided insights for new models of human infectious diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,475,525May 6, 2021April 30, 2026MITCHELL, PATRICK Sreporter.nih.gov
Malaria associated pathogenesis of chronic kidney disease (MAP-CKD)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,470,944June 1, 2025May 31, 2027CONROY, ANDREA L.reporter.nih.gov
Development of a pre-erythrocytic P. vivax vaccine to prevent clinical relapseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,467,626January 1, 2019December 31, 2023SATHER, D. NOAHreporter.nih.gov
Drug Target Discovery, Validation, and Prioritization for SchistosomiasisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,457,864December 20, 2022November 30, 2027COLLINS, JAMES Jreporter.nih.gov
Impairment of anti-Plasmodium T cell memory by type I Interferon SignalingNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,456,734June 1, 2023May 31, 2028MINKAH, NANA KWAKUreporter.nih.gov
Genital Immune, Mucosal, and Viral Effects of Female Genital Schistosomiasis in TanzaniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,453,764March 25, 2022February 28, 2027DOWNS, JENNIFER ALZOSreporter.nih.gov
Innovative therapeutic strategies to support elimination of river blindnessNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,445,389September 11, 2023August 31, 2027MITREVA, MAKEDONKAreporter.nih.gov
Molecular Aspects of Tsetse and Trypanosome TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,438,925January 11, 2019December 31, 2025AKSOY, SERAPreporter.nih.gov
Sex ratio distortion in Aedes aegyptiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,436,620September 16, 2020August 31, 2025TU, ZHIJIAN JAKEreporter.nih.gov
Long-term neurocognitive outcomes of HIV-exposed uninfected childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$2,434,267July 17, 2022June 30, 2026LAUFER, MIRIAM K.reporter.nih.gov
Identification of novel anthelmintics through a target-based screen of a parasite ion channelNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,419,635March 5, 2021February 28, 2026MARCHANT, JONATHAN Sreporter.nih.gov
Immunity to Liver-stage malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,414,340January 12, 2022January 14, 2025HARTY, JOHN Treporter.nih.gov
Epidemiology and determinants of emerging artemisinin-resistant malaria in EthiopiaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,413,258June 9, 2023May 31, 2028PARR, JONATHAN BOYDreporter.nih.gov
Olfactory modulation of color vision and behavior in mosquitoesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,412,809February 16, 2023January 31, 2028RIFFELL, JEFFREY Areporter.nih.gov
Toward novel therapies against Lyme disease through the inhibition of lysinoalaine cross-linking in the bacterial flagella.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,405,876August 16, 2021July 31, 2025CRANE, BRIAN Rreporter.nih.gov
Defining the role of the RNA modification N6-methyladenosine during Flaviviridae virus infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,403,276June 1, 2016January 31, 2027HORNER, STACY MICHELLEreporter.nih.gov
UV to blue neuronal phototransduction mechanismsNIHNational Institute of General Medical Sciences2021 to 2025$2,402,747April 1, 2018March 31, 2028HOLMES, TODD Creporter.nih.gov
Elucidating the Role of Endocytosis Via the Cytostome in the Life Cycle of Trypanosoma cruziNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,399,085June 1, 2021May 31, 2027ETHERIDGE, RONALD DREWreporter.nih.gov
An Informed Approach to Live Attenuated Vaccines against Encephalitis AlphavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,389,767June 12, 2020May 31, 2025KLIMSTRA, WILLIAM Breporter.nih.gov
Innate Immune Regulation of Zika Virus InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,388,284March 1, 2019February 28, 2025GALE, MICHAELreporter.nih.gov
Cyclic di-AMP-dependent signaling in tickborne relapsing fever BorreliaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,380,916August 8, 2022July 31, 2027BLEVINS, JON SCOTTreporter.nih.gov
Impact of malaria on shaping immunity to EBV in the etiology of Burkitt lymphomaNIHNational Cancer Institute2021 to 2024$2,374,490July 10, 2014June 30, 2025MOORMANN, ANN Mreporter.nih.gov
Liver resident memory for malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,368,344November 23, 2018October 31, 2024MURPHY, SEAN Creporter.nih.gov
Maturation of human humoral immunity through repeat malaria challengesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,367,571May 24, 2023April 30, 2028WILLIAMSON, KIM Creporter.nih.gov
Conserved mechanisms of ciliary signaling and cell-cell fusionNIHNational Institute of General Medical Sciences2022 to 2025$2,363,676September 20, 2022June 30, 2027SNELL, WILLIAM Jreporter.nih.gov
Rigorous Assessment of P. vivax Relapses and Primaquine Efficacy for Radical CureNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,362,550July 17, 2020June 30, 2026SERRE, DAVIDreporter.nih.gov
Parasite and host cell factors involved in the formation and persistence of Plasmodium vivax hypnozoitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,358,624February 9, 2023January 31, 2028KAPPE, STEFAN HIreporter.nih.gov
From Drosophila Immunity to Anti-InflammatoriesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,351,847February 15, 2004November 30, 2027SILVERMAN, NEALreporter.nih.gov
Role of human innate immune mutations in loss of tolerance to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,344,769September 8, 2020August 31, 2025HU, LINDEN Treporter.nih.gov
Virulence Mechanisms of Multifunctional Borrelial ProteinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,337,463June 15, 2020August 16, 2024GARCIA, BRANDON LEEreporter.nih.gov
Hijacking Plasmodium ubiquitin-proteasome system to defeat drug resistanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,334,364July 1, 2023June 30, 2028LIN, GANGreporter.nih.gov
Durable Schistosome induced metabolic alterations to the myeloid lineageNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,333,788March 5, 2021February 28, 2026FAIRFAX, KEKE CELESTEreporter.nih.gov
The Biology of Stem Cells in the Human Parasite Schistosoma MansoniNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,328,971February 1, 2016January 31, 2026COLLINS, JAMES Jreporter.nih.gov
Reassortment of Bunyavirus in ticks and animal modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,326,633August 19, 2022July 31, 2027JUNG, JAE Ureporter.nih.gov
Flavivirus immunity in endemic and non-endemic human cohortsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,322,225February 16, 2021January 31, 2027MESSER, WILLIAMreporter.nih.gov
Developing methionyl tRNA synthetase inhibitors as therapeutics for Chagas diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,320,008April 1, 2020March 31, 2026FAN, ERKANGreporter.nih.gov
Characterizing the role of LDL related receptor 1 (Lrp1) as host entry factor for multiple bunyavirusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,318,306March 14, 2023February 29, 2028AMARASINGHE, GAYA K.reporter.nih.gov
Investigations of Lyme spirochete transmission as a complex network of microbial and ecological interactionsNIHNational Institute of General Medical Sciences2022 to 2025$2,315,379September 16, 2022July 31, 2027COURET, JANNELLEreporter.nih.gov
Elucidating the functions of red blood cell factors in malaria parasite invasionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,314,537July 1, 2023June 30, 2028EGAN, ELIZABETH S.reporter.nih.gov
Anti-flavivirus B cell response analysis to aid vaccine designNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,304,231February 6, 2023January 31, 2028LI, YUXINGreporter.nih.gov
Resolving the properties of schistosome TRPMPZQ, the target of the anthelmintic drug praziquantelNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,302,312April 1, 2020March 31, 2030MARCHANT, JONATHAN Sreporter.nih.gov
Development of Inhibitors Targeting Flavivirus MethyltransferaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,302,146April 7, 2023March 31, 2028LI, HONGMINreporter.nih.gov
A Self-Adjuvanting Virus Like Particle Vaccine Platform for Emerging VirusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,297,827June 8, 2023May 31, 2028DEFILIPPIS, VICTOR ROBERTreporter.nih.gov
Surveillance to track and characterize antimalarial resistance trends in Ugandan Plasmodium falciparum parasites (STARTUP)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,293,828December 20, 2022November 30, 2025CONRAD, MELISSA Dreporter.nih.gov
Orientia tsutsugamushi Ank-host interactions in scrub typhus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,292,269February 15, 2022January 31, 2027CARLYON, JASON Areporter.nih.gov
Mechanisms of Neuronal Infection by Prototype Emerging BunyavirusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,287,685August 7, 2023July 31, 2027HARTMAN, AMY Lreporter.nih.gov
TMEM41B: a pan-flavivirus and pan-coronavirus host factor with antiviral potentialNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,286,496September 19, 2022July 31, 2027RICE, CHARLES Mreporter.nih.gov
Emerging Flea-Borne Rickettsial Diseases: vector competence and transmission biologyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,286,335December 1, 2015July 31, 2027MACALUSO, KEVIN R.reporter.nih.gov
Identity, function and control of Francisella effectors encoded outside its pathogenicity islandNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,279,849July 1, 2019June 30, 2025MOUGOUS, JOSEPH DAVIDreporter.nih.gov
Development of next-generation gene drive technologies for Anopheles population engineeringNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,276,593June 1, 2021May 31, 2026BIER, ETHANreporter.nih.gov
A modular platform for infectious disease surveillance at point-of-need.NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,274,286August 7, 2020August 31, 2025FISHER, JAY KENNETHreporter.nih.gov
Regulation of RIG-I signaling and viral immune evasion by ufmylationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,272,375June 1, 2021May 31, 2026HORNER, STACY MICHELLEreporter.nih.gov
Dengue virus mRNA lipid nanoparticle vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,268,440August 12, 2021July 31, 2025RICHNER, JUSTINreporter.nih.gov
Aedes antiviral RNAi pathwayNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,267,812November 20, 2018October 31, 2025DIMOPOULOS, GEORGEreporter.nih.gov
Development of a Virus-Like Particle Vaccine for Powassan VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,265,539June 1, 2020May 31, 2026HIRSCH, ALEC Jreporter.nih.gov
Defining P. falciparum resistance to artemisinin-based combination therapiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,262,645August 1, 2014February 28, 2027FIDOCK, DAVID Areporter.nih.gov
SFTSV nonstructural protein NSs-mediated immunopathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,260,994July 1, 2018June 30, 2024JUNG, JAE Ureporter.nih.gov
Long Term Immunity Following Yellow Fever VaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,259,248February 5, 2020January 31, 2026MESSER, WILLIAMreporter.nih.gov
Develop a candidate subunit vaccine for Powassan Virus and West Nile virus adjuvanted with Alhydroxiquim-IINIHNational Institute of Allergy and Infectious Diseases2022$2,258,969September 30, 2018September 29, 2023DAVID, SUNILreporter.nih.gov
Tickborne SFTS Virus Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,258,000August 3, 2020July 31, 2026JUNG, JAE Ureporter.nih.gov
Sex determination and the sex-determining locus in aedine mosquitoesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,254,128July 14, 2023June 30, 2028TU, ZHIJIAN JAKEreporter.nih.gov
Disentangling the human vector relationship to disrupt dengue and chikungunya virus outbreaks in KenyaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,253,756July 5, 2013April 30, 2025LABEAUD, ANGELLE DESIREEreporter.nih.gov
US-UK Collab: Modelling reassortment at the cellular, clinical, and phylogenetic level in emerging BunyavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,245,998July 1, 2021June 30, 2027MOLINA-PARIS, CARMENreporter.nih.gov
Mechanisms of Antibody-Dependent Enhancement of Dengue DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,244,008September 24, 2018August 31, 2028BOURNAZOS, STYLIANOSreporter.nih.gov
Developing New Statistical Methods for Vector-Borne Disease Surveillance to Improve Accuracy while Reducing CostNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,240,192September 19, 2023July 31, 2028SELF, STELLA COKER WATSONreporter.nih.gov
CD8 T cell-dependent pathways leading to immunopathology in cutaneous leishmaniasisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,230,533February 12, 2020January 31, 2025SCOTT, PHILLIPreporter.nih.gov
CD8 T cell mediated disruption of Blood Brain Barrier Tight JunctionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,226,916July 1, 2017February 28, 2030JOHNSON, AARON Jreporter.nih.gov
MEP pathway resistance in Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,223,785December 1, 2012March 31, 2028ODOM JOHN, AUDREY RAGANreporter.nih.gov
Elucidating Chemical Signaling Mechanisms that Regulate Multicellularity and the Transmission of Infectious DiseaseNIHNational Institute of General Medical Sciences2021 to 2025$2,219,184August 1, 2020July 31, 2030GERDT, JOSEPH P.reporter.nih.gov
ANTIBODY-BASED PROTECTION AGAINST FLAVIVIRUSESNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,212,878September 15, 2007January 31, 2029DIAMOND, MICHAEL Sreporter.nih.gov
OspC and its role in defining host range and dissemination propertiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,211,024August 1, 2022July 31, 2026MARCONI, RICHARD Treporter.nih.gov
SpoVG and PlzA Regulation of Lyme Disease Spirochete Infection ProcessesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,207,935April 1, 2020March 31, 2026STEVENSON, BRIANreporter.nih.gov
Etiology of Persistent Microalbuminuria in NigeriaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,202,068July 1, 2021May 31, 2026WESTER, C. WILLIAMreporter.nih.gov
Composition, Atomic Structure and Function of the Francisella Type 6 Secretion System, a Distinct Subtype Essential for Phagosomal Escape, Intracellular Replication, and VirulenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,198,656September 21, 2020August 31, 2025HORWITZ, MARCUS AARONreporter.nih.gov
Quasispecies dynamics in arbovirus persistence emergence and fitnessNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,197,799May 15, 2007January 31, 2027EBEL, GREGORY DAVIDreporter.nih.gov
Rocky Mountain Spotted Fever Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,192,703September 1, 2021August 31, 2027GANTA, ROMAN R.reporter.nih.gov
Probing Functional States and Inhibition of Flaviviral Proteases Using Nanopore TweezersNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,190,088June 10, 2021May 31, 2027CHEN, MINreporter.nih.gov
Biogenic amines, malaria and manipulation of mosquito physiology and behavior.NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,184,819August 8, 2022July 31, 2027LUCKHART, SHIRLEYreporter.nih.gov
Borrelia gene products critical for natural infection cycleNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,181,619July 1, 2009July 31, 2025PAL, UTPALreporter.nih.gov
Identification of the initial cells infected by West Nile virus ex vivo and in vivoNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,178,310September 21, 2022July 31, 2027LIM, JEAN KYOUreporter.nih.gov
Impact of inflammatory lipids on Yersinia pestis infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,171,406July 14, 2023June 30, 2027LAWRENZ, MATTHEW Breporter.nih.gov
Characterizing sexual development of the human parasite Schistosoma mansoniNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,152,107July 1, 2020June 30, 2025COLLINS, JAMES Jreporter.nih.gov
The paradox of flavivirus antigenic non-reciprocityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,146,248July 24, 2024May 31, 2029FRIEDRICH, THOMAS C.reporter.nih.gov
Non-inferiority trial of a therapeutic vaccine against Chagas disease in naturally-infected rhesus macaquesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,145,891February 16, 2023January 31, 2028DUMONTEIL, ERICreporter.nih.gov
Investigating astrocytic RIPK3 as a driver of protective neuroinflammation during viral encephalitisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,142,099February 15, 2021January 31, 2027DANIELS, BRIANreporter.nih.gov
Role of IgE in human disease and immunity to ticksNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,139,543March 20, 2024January 31, 2026SMITH, SCOTT ALANreporter.nih.gov
Predictors of cardiomyopathy progression in a Chagas disease cohort in BoliviaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,136,387February 15, 2014June 30, 2024GILMAN, ROBERT Hreporter.nih.gov
Mechanisms of alphavirus infectivity and adaptation - Resubmission - 1NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,136,232February 1, 2022January 31, 2027STAPLEFORD, KENNETHreporter.nih.gov
Mechanisms of viral RNA maturation by co-opting cellular exonucleasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,134,101June 1, 2023May 31, 2027KIEFT, JEFFREY Sreporter.nih.gov
Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,130,877May 1, 2025April 30, 2027ELLIOTT, ALISONreporter.nih.gov
Biogenesis of the Trypanosoma brucei subpellicular microtubule arrayNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,127,931September 17, 2021August 31, 2026DE GRAFFENRIED, CHRISTOPHER LUISreporter.nih.gov
Defining the mechanism of coma in cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,123,692July 8, 2022June 30, 2027DAILY, JOHANNA PATRICIAreporter.nih.gov
Multi-Omics Characterization of Plasmodium Vivax HypnozoitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,118,231December 22, 2022November 30, 2027SERRE, DAVIDreporter.nih.gov
Orally Bioavailable 4(1H)-Quinolones with Multi-Stage Antimalarial ActivityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,114,325April 11, 2019March 31, 2025MANETSCH, ROMANreporter.nih.gov
Genome-wide sieve analysis and immunological validation to identify targets of protective efficacy in field trials of a whole-organism malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,110,841January 15, 2019December 31, 2024CARNEIRO DA SILVA, JOANAreporter.nih.gov
The role of natural killer cells and antibodies in protection from malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,108,688March 25, 2020February 28, 2026HART, GEOFFREY Treporter.nih.gov
Molecular genetics of gustatory detectionNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,107,835July 1, 2006June 30, 2026MONTELL, CRAIGreporter.nih.gov
Essential early events in the flavivirus lifecycleNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,093,750March 9, 2021February 28, 2027UCHIL, PRADEEP Dreporter.nih.gov
Control of VSG pre-mRNA processing in infectious Trypanosoma bruceiNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,093,750September 23, 2021August 31, 2026TSCHUDI, CHRISTIANreporter.nih.gov
Intra-tick and intra-host infection dynamics of a tick-borne bunyavirusNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,092,645July 1, 2022June 30, 2027HERMANCE, MEGHAN ELIZABETHreporter.nih.gov
PlzA, cyclic-di-GMP and the enzootic cycle for Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,090,540November 18, 2022October 31, 2027MARCONI, RICHARD Treporter.nih.gov
Repurposing human kinase inhibitor chemotypes for Neglected Tropical DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,089,227December 4, 2014March 31, 2026FERRINS, LORIreporter.nih.gov
Mechanism and Inhibition of Thogotovirus EntryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,085,008November 22, 2022October 31, 2027BOON, ADRIANUS CMreporter.nih.gov
THE IDENTIFICATION AND VALIDATION OF EPITOPES CONSERVED IN VIRAL PATHOGEN FAMILIES WITH PANDEMIC POTENTIALNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,080,465September 30, 2025September 29, 2026FABRITZKY, BRANDONreporter.nih.gov
Interplay between AMPK and Hippo Signaling Regulates Ocular Antiviral Response to Zika virus infectionNIHNational Eye Institute2021 to 2024$2,079,783January 1, 2021December 31, 2025ARUMUGASWAMI, VAITHILINGARAJAreporter.nih.gov
Innate immune signaling in placental antiviral defensesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,078,112July 17, 2019June 30, 2025COYNE, CAROLYN Breporter.nih.gov
New tools for tick-borne pathogen surveillanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,075,697December 8, 2022November 30, 2027OLIVER, JONATHAN Dreporter.nih.gov
Field trial and modeling of transmission blocking vaccine to prevent Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,072,628June 19, 2019May 31, 2025BROWN, GRANT Dreporter.nih.gov
Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,067,031April 1, 2003June 30, 2029GILBERT, PETER B.reporter.nih.gov
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile ImmunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,065,107August 23, 2023July 31, 2027MILICH, DAVID R.reporter.nih.gov
Esophageal gland-mediated immune evasion by the human parasite Schistosoma mansoniNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,064,827August 24, 2023July 31, 2028LEE, JAYHUNreporter.nih.gov
The roles of Anaplasma phagocytophilum surface proteins in infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,062,336July 15, 2007June 30, 2027CARLYON, JASON Areporter.nih.gov
Peptide regulation of mosquito blood feeding and matingNIHNational Institute of General Medical Sciences2021 to 2025$2,059,337August 1, 2020August 31, 2030DUVALL, LAURAreporter.nih.gov
Task A71: Comprehensive In Vivo Screening of Viral Pathogens of Pandemic PotentialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,055,396August 3, 2022August 2, 2025BOWEN, RICHARD ARNOLDreporter.nih.gov
Defining correlates of protection from dengue illness in a long-term cohort study of multigenerational house-holds in ThailandNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,054,463July 1, 2025June 30, 2028ANDERSON, KATHRYN Breporter.nih.gov
Plasmodium falciparum gametocytogenesis in vitro and in vivoNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,054,301January 8, 2020December 31, 2025WILLIAMSON, KIM Creporter.nih.gov
Trade-offs between Arbovirus Transmission and Clearance in Native and Novel HostsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,054,277February 24, 2020January 31, 2025HANLEY, KATHRYN ALYCEreporter.nih.gov
The evolutionary genetics and genomics of Wolbachia effects on host physiologyNIHNational Institute of General Medical Sciences2021 to 2025$2,054,249August 4, 2017July 31, 2027COOPER, BRANDON S.reporter.nih.gov
Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,049,089July 11, 2022June 30, 2027SHAW, DANA KATHLEENreporter.nih.gov
The role of stem-cell mediated midgut repair in the dynamics of mosquito infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,045,645June 5, 2020May 31, 2026BUCHON, NICOLASreporter.nih.gov
Systemic Neurotropic virus infection effects on GI DysmotilityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,043,482July 1, 2020April 30, 2025STAPPENBECK, THADDEUS Sreporter.nih.gov
Schistosomiasis at the edge of elimination: characterizing sources of new infections in residual transmission hotspotsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,041,847November 23, 2018October 31, 2025CARLTON, ELIZABETHreporter.nih.gov
The essential role of cyclin-dependent kinase CRK9 in trypanosome pre-mRNA processingNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,037,700March 2, 2021February 28, 2027GUNZL, ARTHURreporter.nih.gov
Vanderbilt University Medical Center (VUMC) CoFAR Clinical Research CenterNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,036,652March 14, 2024February 28, 2031BACHARIER, LEONARD Breporter.nih.gov
Function and Trafficking of Flagellar Membrane Proteins in Leishmania mexicanaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,026,198May 22, 2023April 30, 2028LANDFEAR, SCOTT Mreporter.nih.gov
Function of hemolymph plasma proteins in insect immune responsesNIHNational Institute of General Medical Sciences2021 to 2025$2,022,182May 1, 2021February 28, 2027KANOST, MICHAEL Rreporter.nih.gov
The Function of Antimalarial Drug Resistance ProteinsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,016,655June 15, 2003October 31, 2026ROEPE, PAUL D.reporter.nih.gov
Scramblases for protein glycosylationNIHNational Institute of General Medical Sciences2022 to 2025$2,015,483April 1, 2022March 31, 2027MENON, ANANT Kreporter.nih.gov
Germline Transformation of TicksNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,013,002May 11, 2023April 30, 2028GULIA-NUSS, MONIKAreporter.nih.gov
The evolution of copy number variations in the AT-rich Plasmodium genomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,000,646April 1, 2021March 31, 2027GULER, JENNIFER LYNNreporter.nih.gov
FH-Fc as a Pre-Exposure Prophylactic for Tickborne DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,000,000July 17, 2020April 30, 2025WYCOFF, KEITHreporter.nih.gov
Commercialization Readiness Pilot (CRP) program support for: Ultra-sensitive, direct-from-blood, molecular detection of Borrelia infections.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,000,000April 2, 2024March 31, 2027SINGER, ALONreporter.nih.gov
Recombinant Outer Membrane Vesicles as a Novel Adjuvant for a Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,755December 8, 2023November 30, 2026LOCHER, CHRISTOPHERreporter.nih.gov
Rapid Point-of-Care RNA Diagnostic for Dengue InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,999,598March 15, 2019July 31, 2025CHO, HYUNDAEreporter.nih.gov
REPEAT-CONTAINING RNA BINDING PROTEINS OF TRYPANOSOMESNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,998,600January 5, 2015January 31, 2026AFASIZHEVA, INNAreporter.nih.gov
Role of microglia in neural infectionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,997,135January 15, 2022December 31, 2026WU, PINGreporter.nih.gov
Manufacture of aseptic, purified, cryopreserved Plasmodium vivax sporozoitesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,995,482April 21, 2016July 31, 2027CHAKRAVARTY, SUMANAreporter.nih.gov
Malarial retinopathy screening system for improved diagnosis of cerebral malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,992,098May 6, 2021April 30, 2024JOSHI, VINAYAK Sreporter.nih.gov
Targeted Prevention of Human EhrlichiosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,991,816August 17, 2021July 31, 2027RIKIHISA, YASUKOreporter.nih.gov
Development of Next-gen Chagas DetectTM Plus Rapid test for sensitive and specific diagnosis of Chagas diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,988,974May 8, 2024April 30, 2027RAYCHAUDHURI, SYAMAL Xreporter.nih.gov
The role of pattern recognition and autophagy in innate anti-bunyaviral immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,986,831September 23, 2019August 31, 2025CHERRY, SARAreporter.nih.gov
Role of Zika virus (ZIKV) infection in glaucoma pathobiologyNIHNational Eye Institute2021 to 2025$1,980,186September 1, 2021August 31, 2027SINGH, PAWAN KUMARreporter.nih.gov
PfSPZ Vaccine for Malaria: Towards a Successful Biologics License Application and CommercializationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,973,577February 15, 2004June 30, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
Development of an automated IVD for the ultra-sensitive, direct, molecular detection of Borrelia for early Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,972,995June 15, 2020May 31, 2024SINGER, ALONreporter.nih.gov
Reproductive Responses to the Zika Virus Epidemic in BrazilNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,969,272September 15, 2018June 30, 2023MARTELETO, LETICIA Jreporter.nih.gov
Structural Studies of TogavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,968,857February 20, 2012January 31, 2025KUHN, RICHARD J.reporter.nih.gov
A Randomized Phase I Clinical Trial of HydroVax-CHIKV, a Novel Inactivated Chikungunya Virus VaccineNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,967,096July 1, 2020June 30, 2027AMANNA, IAN JAMESreporter.nih.gov
An immune system for the city: a new paradigm for control of urban disease vectorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,967,064July 1, 2019June 30, 2025LEVY, MICHAEL Zreporter.nih.gov
Brain pathology and function in a chronic mouse model of ZIKV transmissionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,965,040April 1, 2019March 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
Advancing evolutionary genetics through deep learningNIHNational Institute of General Medical Sciences2021 to 2025$1,962,893July 1, 2020April 30, 2030SCHRIDER, DANIEL Rreporter.nih.gov
Mechanisms of visual transduction and light-driven behaviors in Aedes aegyptiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,960,699January 1, 1995January 31, 2027MONTELL, CRAIGreporter.nih.gov
Model-based inference and forecasting of co-circulating pathogen dynamicsNIHNational Institute of General Medical Sciences2021 to 2025$1,956,250September 24, 2021June 30, 2027PERKINS, ALEXreporter.nih.gov
Ultrasensitive, High-Specificity Rapid Test to Support the End-Game of the Global Program to Eliminate Lymphatic FilariasisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,954,629May 1, 2022June 30, 2027BIAMONTE, MARCO ANTONIOreporter.nih.gov
Mechanistic Analysis of Zika Virus Induced Placental Damage During PregnancyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,951,673June 1, 2019May 31, 2025STREBLOW, DANIEL Nreporter.nih.gov
Identifying functional antibody responses that protect against malaria in childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,938,902August 1, 2025July 31, 2027SEYDEL, KARL BOYNTONreporter.nih.gov
Employing viruses to unravel the functional significance of the m5C epitranscriptomeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,938,825February 7, 2023January 31, 2028RICE, CHARLES Mreporter.nih.gov
Manufacture of aseptic, purified, cryopreserved Plasmodium vivax sporozoitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,938,759April 21, 2016May 31, 2024CHAKRAVARTY, SUMANAreporter.nih.gov
Perturbations of host cell signaling by a complex hepatotropic pathogenNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,938,593April 1, 2013January 31, 2028KAUSHANSKY, ALEXISreporter.nih.gov
A point of care vertical flow assay for the direct detection of Babesia microti and the serodiagnosis of Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,933,868July 1, 2024February 28, 2027DATTWYLER, RAYMOND JAMESreporter.nih.gov
Exploring the coevolutionary potential of chikungunya virus and its Aedes mosquito vectorsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,932,881May 19, 2023April 30, 2028MCGRAW, ELIZABETH ANNreporter.nih.gov
Mechanistic Insights into flavivirus NS5-mediated STAT2 SuppressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,932,088March 15, 2021February 28, 2026HAI, RONGreporter.nih.gov
Cryopreservation of Anopheles EmbryosNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,928,928August 1, 2010January 31, 2024BILLINGSLEY, PETER F.reporter.nih.gov
Comprehensive Definition of the Critical Role(s) of the Alphaviral Noncapped Genomic RNAs to Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,927,696May 21, 2020April 30, 2026SOKOLOSKI, KEVIN JOSEPHreporter.nih.gov
Modeling the influence of temperature on the evolution of vector-virus interactionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,926,486February 3, 2022January 31, 2027CIOTA, ALEXANDER TIMOTHYreporter.nih.gov
Dissecting the role of EBV and P. falciparum in endemic Burkitt lymphoma pathogenesisNIHNational Cancer Institute2021 to 2023$1,923,862August 14, 2019January 31, 2025LUFTIG, MICAH A.reporter.nih.gov
Impairment of B cell Responses by Pathogenic Chikungunya VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,921,199January 25, 2019December 31, 2024MORRISON, THOMAS Ereporter.nih.gov
Identifying Wolbachia effectors that facilitate host infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,918,425May 10, 2019March 31, 2029NEWTON, IRENEreporter.nih.gov
Defining the immunogenic landscape of early mosquito-stage P. falciparum to accelerate malaria transmission-blocking vaccine discoveryNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,917,896July 5, 2024May 31, 2029SWEARINGEN, KRISTIAN EDWARDreporter.nih.gov
Development of a multiplexed assay in kinetoplastid parasites to identify probes for glycolysisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,915,091April 3, 2021March 31, 2026MORRIS, JAMES CULVINreporter.nih.gov
In-Vitro Culture of Plasmodium falciparum Sporozoites for Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,912,715February 15, 2010May 31, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Trypanosoma cruzi dormancy and its implications for therapeutic treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,908,036March 10, 2020February 28, 2026TARLETON, RICK Lreporter.nih.gov
Molecular Mechanisms Underlying Insect Odorant Receptor Function and ModulationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,907,239December 15, 2013November 30, 2025RUTA, VANESSAreporter.nih.gov
Understanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,906,728September 19, 2008January 31, 2027LI, CHUNHAO CHRISreporter.nih.gov
Antibody-based Protection against FlavivirsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,903,581September 15, 2007March 13, 2024DIAMOND, MICHAEL Sreporter.nih.gov
Functional analysis of host and viral determinants for ZAP inhibitionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,901,640April 1, 2021March 31, 2027LI, MELODYreporter.nih.gov
Molecular mechanisms of schizogony in malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,900,856June 1, 2019May 31, 2025DVORIN, JEFFREY Dreporter.nih.gov
Dissection of molecular events driving alphavirus entry and assemblyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,900,539August 15, 1995November 30, 2024KIELIAN, MARGARETreporter.nih.gov
Natural Product Inspired Novel Antimalarials with Radical Cure PotentialNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,900,470April 4, 2023March 31, 2028KANCHARLA, PAPIREDDYreporter.nih.gov
Uncovering and harnessing connected metabolic pathways essential to virus infection.NIHNational Institute of General Medical Sciences2021 to 2025$1,891,981September 1, 2020May 31, 2030MOUNCE, BRYAN Creporter.nih.gov
Role of Translesional Polymerases in Genome Diversification of the Malaria ParasiteNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,889,240June 10, 2019May 31, 2025KIRKMAN, LAURAreporter.nih.gov
Type-I Interferons drive cell-autonomous immunity to malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,887,500June 21, 2022May 31, 2027KURUP, SAMreporter.nih.gov
Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigationNIHNational Institute of General Medical Sciences2021 to 2025$1,886,759August 23, 2016May 31, 2026BEDFORD, TREVOR BCreporter.nih.gov
Discovery of early immunologic biomarkers for risk of PTLDS through machine learning-assisted broad temporal profiling of humoral immune responseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,885,162July 7, 2023June 30, 2028WOODBURY, NEAL WALTERreporter.nih.gov
Slo-1K channels, TRP-2 channels, emodepside and diethylcarbamazine in FilariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,876,476September 16, 2020August 31, 2025MARTIN, RICHARD JOHNreporter.nih.gov
Safety and Immunogenicity of novel, live-attenuated V4020 vaccine for Venezuelan Equine Encephalitis (VEE) in healthy adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,876,310March 1, 2022February 28, 2026PUSHKO, PETER M.reporter.nih.gov
Efficacy of novel reservoir-host targeted bait formulations against a tick-borne pathogenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,875,000September 1, 2021August 31, 2026SESHU, JANAKIRAMreporter.nih.gov
Unlocking serology’s secrets: harnessing novel immune biomarkers to predict Lyme disease progression and recoveryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,872,987July 1, 2023June 30, 2028TAL, MICHAL CASPIreporter.nih.gov
Next Generation Infectious Disease Diagnostics: Microfluidic-Free Gigapixel PCR with Self-Assembled PartitioningNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,871,100June 15, 2023May 31, 2028ABATE, ADAM R.reporter.nih.gov
Regulation of cell cycle transitions by cyclin-dependent kinase in trypanosomesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,869,624May 13, 2016April 30, 2027LI, ZIYINreporter.nih.gov
Virulence regulation by BadR in the Lyme disease spirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,868,750March 24, 2021February 28, 2027OUYANG, ZHIMINGreporter.nih.gov
Determinants of Post-Treatment Phenotypes in Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,868,460July 1, 2023June 30, 2028AUCOTT, JOHNreporter.nih.gov
Statistical innovation to integrate sequences and phenotypes for scalable phylodynamic inferenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,862,316April 9, 2021March 31, 2026SUCHARD, MARC A.reporter.nih.gov
Innate immune recognition and response to Rift Valley fever virusNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,861,528August 25, 2022July 31, 2027MCELROY, ANITA Kreporter.nih.gov
How to starve a parasite: Manipulating CoA biosynthesis to control Plasmodium development in the mosquitoNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,855,815April 14, 2023March 31, 2027RIEHLE, MICHAEL ALLENreporter.nih.gov
Biomarkers to Identify Individuals at RIsk for Progression of S. Japonicum Associated Hepatic Fibrosis with Point of Care Test DevelopmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,852,531June 1, 2022March 31, 2027FRIEDMAN, JENNIFER Freporter.nih.gov
Clearance of Blood-Borne ArbovirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,851,575January 21, 2020December 31, 2025MORRISON, THOMAS Ereporter.nih.gov
Transfusion-related immunomodulation influences infectious disease outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,851,251September 1, 2020June 30, 2025SIMMONS, GRAHAMreporter.nih.gov
Genetic mechanisms of snail/schistosome compatibilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,848,750January 10, 2019May 31, 2028BLOUIN, MICHAEL SCOTTreporter.nih.gov
Precision guided SIT for the control of vector-borne diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,847,066January 23, 2020December 31, 2024AKBARI, OMAR SULTANreporter.nih.gov
Primaquine metabolism and treatment of P. vivax in MadagascarNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,843,113January 1, 2020September 19, 2023ZIMMERMAN, PETER A.reporter.nih.gov
Virus-like Particle based malaria vaccines targeting vulnerable epitopes in the circumsporozoite proteinNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,841,511November 9, 2022October 31, 2027CHACKERIAN, BRYCE Creporter.nih.gov
Host and parasite determinants of Leishmania Viannia persistence in naturally infected human populationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,833,337December 28, 2022November 30, 2027EL-SAYED, NAJIB Mreporter.nih.gov
Auto-antibodies as predictive markers for Post treatment Lyme Disease SyndromeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,830,220July 5, 2023June 30, 2028HU, LINDEN Treporter.nih.gov
SUPPORTING WHO ONCHOCERCIASIS ELIMINATION PROGRAMS: PROGRESSING A HIGHLY SENSITIVE AND ULTRA-SPECIFIC RAPID DIAGNOSTIC TEST TO COMMERCIALIZATION READINESSNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,829,744March 16, 2023February 28, 2026BIAMONTE, MARCO ANTONIOreporter.nih.gov
Genome-based diagnostics for mapping, monitoring and management of insecticide resistance in major African malaria vectorsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,808,286February 15, 2016May 31, 2027DONNELLY, MARTIN JAMESreporter.nih.gov
Targeting a New Therapy for TrypanosomatidsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,805,632June 12, 2019May 31, 2025WETZEL, DAWN MARIEreporter.nih.gov
Mosquito hydration status as a mechanism that alters pre-feeding host interactions and post-feeding physiologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,800,822June 12, 2020May 31, 2026BENOIT, JOSH B.reporter.nih.gov
Optimizing HIV-malaria treatment in a shifting treatment and resistance landscape in AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,796,782December 23, 2010June 30, 2029PARIKH, SUNILreporter.nih.gov
Partial maturation in mosquito-borne flaviviruses: developing new approaches to characterize the role of lattice heterogeneity in fusion, infectivity, and antibody neutralizationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,790,590January 20, 2022December 31, 2026METSKAS, LAUREN ANNreporter.nih.gov
Antiviral and immunomodulatory effects of interferon lambda in the skinNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,784,166March 13, 2023February 29, 2028LAZEAR, HELENreporter.nih.gov
POLYAMINE AND TRYPANOTHIONE METABOLISM IN TRYPANOSOMA BRUCEINIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,783,125December 1, 1994June 30, 2026PHILLIPS, MARGARET A.reporter.nih.gov
Extent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplificationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,777,806July 1, 2025June 30, 2028POPOVICI, JEANreporter.nih.gov
Snail-Related Studies of Transmission & Control of Schistosomiasis in KenyaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,777,676May 15, 2012April 30, 2027LOKER, ERIC SAMUELreporter.nih.gov
Impacts of phenology on disease transmission dynamicsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,776,375August 1, 2023July 31, 2028BRISSON, DUSTINreporter.nih.gov
Immunological characterization of the P. vivax DBPNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,773,948August 1, 2006March 31, 2026ADAMS, JOHN Hreporter.nih.gov
A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virusNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,768,228June 7, 2024April 30, 2029SHRESTA, SUJANreporter.nih.gov
Innate Immunity to West Nile VirusNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,763,090July 1, 2024May 31, 2029OBERST, ANDREW ATWELLreporter.nih.gov
Antibody-mediated immunity to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,759,416March 8, 2021February 28, 2027BAUMGARTH, NICOLEreporter.nih.gov
Essential PK/PD relationships of antimalarial drugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,753,200February 1, 2012August 31, 2025SHAPIRO, THERESA Areporter.nih.gov
The role of ascorbate in myelopoiesis and infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,753,030April 1, 2021July 31, 2026AGATHOCLEOUS, MICHALISreporter.nih.gov
Caspase-8 as a focal hub in effector-triggered immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,752,183May 10, 2019April 30, 2025LIEN, EGILreporter.nih.gov
Cellular and humoral immunity in Lyme arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,748,421January 8, 2019June 30, 2024STEERE, ALLEN Creporter.nih.gov
DISCOVERY AND PRECLINICAL DEVELOPMENT OF EFFICACIOUS P. vivax PRE-ERYTHROCYTIC STAGE MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,745,498November 20, 2020October 31, 2023HERRERA VALENCIA, SOCRATESreporter.nih.gov
Comprehensive characterization of the genetic factors and the host immune response associated to protection from clinical Plasmodium vivax malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,744,699March 16, 2023February 29, 2028POPOVICI, JEANreporter.nih.gov
Once bitten: A longitudinal, observational study of successful malaria parasite transmission events between humans and mosquitosNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,739,571July 16, 2019June 30, 2024PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Origin of the innate immunity suppression caused by nairovirus' protease activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,738,279September 16, 2020August 31, 2025PEGAN, SCOTT DUSANreporter.nih.gov
A multidisciplinary approach to study ecotypes driving transmission and pathogenesis of Visceral Leishmaniasis (VL) and Post kala-azar dermal leishmaniasis (PKDL) in Eastern AfricaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,736,288April 1, 2025March 31, 2027SATOSKAR, ABHAY Rreporter.nih.gov
Peptide-vaccine development against Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,724,972May 15, 2020April 30, 2026BARBIER, MARIETTEreporter.nih.gov
Mitochondrial Functions in Malaria ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,717,892July 1, 1989October 31, 2028VAIDYA, AKHIL Breporter.nih.gov
Structure-based Vaccine Design for CCHFVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,714,028June 25, 2020November 30, 2025MCLELLAN, JASON SCOTTreporter.nih.gov
ER-shaping proteins of PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,698,924June 1, 2021May 31, 2027BHANOT, PURNIMAreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of WashingtonSeattle, WA40$71.5 million0$0
Washington UniversitySaint Louis, MO48$71.5 million0$0
University of California, San FranciscoSan Francisco, CA45$66.1 million0$0
Emory UniversityAtlanta, GA22$53.6 million0$0
University of Texas Med BR GalvestonGalveston, TX49$53.6 million0$0
Yale UniversityNew Haven, CT41$52.3 million0$0
University of Maryland BaltimoreBaltimore, MD42$45 million0$0
Johns Hopkins UniversityBaltimore, MD47$41.9 million0$0
Seattle Children's HospitalSeattle, WA20$41 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC39$40.1 million0$0
Sanaria, Inc.Rockville, MD20$39.5 million0$0
Duke UniversityDurham, NC31$39 million0$0
Oregon Health & Science UniversityPortland, OR26$38.8 million0$0
University of California-BerkeleyBerkeley, CA13$37 million0$0
Stanford UniversityStanford, CA23$32.8 million0$0
University of Georgia Research Foundation IncAthens, GA31$31.6 million0$0
University of Vermont & ST Agric CollegeBurlington, VT4$29.8 million0$0
Colorado State UniversityFort Collins, CO22$26.4 million0$0
University of Colorado DenverAurora, CO18$26 million0$0
Indiana University IndianapolisIndianapolis, IN23$24.6 million0$0
University of PennsylvaniaPhiladelphia, PA27$24.3 million0$0
Weill Medical Coll of Cornell UnivNew York, NY16$23.4 million0$0
Ut Southwestern Medical CenterDallas, TX16$23.3 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA24$23.1 million0$0
Rockefeller UniversityNew York, NY11$23.1 million0$0
Columbia University Health SciencesNew York, NY16$22.2 million0$0
Saint Louis UniversitySaint Louis, MO4$22 million0$0
Boston Children's HospitalBoston, MA16$21.8 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA31$21.5 million0$0
University of California at DavisDavis, CA15$21.5 million0$0
Tufts University BostonBoston, MA19$21.4 million0$0
Tulane University of LouisianaNew Orleans, LA13$21.3 million0$0
University of California, San DiegoLa Jolla, CA25$21.2 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY11$20.5 million0$0
University of South FloridaTampa, FL20$19.6 million0$0
University of MinnesotaMinneapolis, MN17$18.3 million0$0
University of IowaIowa City, IA18$18.2 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA16$17.7 million0$0
Virginia Commonwealth UniversityRichmond, VA13$17 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA11$16.3 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA5$15.5 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA19$15.4 million0$0
Albert Einstein College of MedicineBronx, NY15$15.1 million0$0
University of California Los AngelesLos Angeles, CA17$15 million0$0
Kaiser Foundation Research InstituteOakland, CA2$14.8 million0$0
Vanderbilt University Medical CenterNashville, TN11$14.6 million0$0
University of VirginiaCharlottesville, VA7$14.3 million0$0
University of California-IrvineIrvine, CA14$14.2 million0$0
University of UtahSalt Lake City, UT16$13.7 million0$0
Cornell UniversityIthaca, NY13$13.7 million0$0
Brown UniversityProvidence, RI15$13.6 million0$0
Washington State UniversityPullman, WA15$13.5 million0$0
University of Maryland, College ParkCollege Park, MD12$13.5 million0$0
University of California-RiversideRiverside, CA15$13.3 million0$0
Ohio State UniversityColumbus, OH12$12.8 million0$0
Drexel UniversityPhiladelphia, PA10$12.8 million0$0
Medical College of WisconsinMilwaukee, WI10$12.7 million0$0
University of Wisconsin-MadisonMadison, WI10$12.7 million0$0
Utah State UniversityLogan, UT2$12.1 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH10$11.9 million0$0
Massachusetts General HospitalBoston, MA9$11.8 million0$0
Boston University Medical CampusBoston, MA11$11.7 million0$0
University of LouisvilleLouisville, KY9$11.7 million0$0
Clemson UniversityClemson, SC3$11.4 million0$0
Abviro, LLCBethesda, MD2$11.4 million0$0
Health Research Incorporated/New York State Department of HealthMenands, NY2$10.8 million0$0
Kephera Diagnostics, LLCFramingham, MA6$10.6 million0$0
New York University School of MedicineNew York, NY12$10.5 million0$0
Massachusetts Institute of TechnologyCambridge, MA5$10.5 million0$0
SUNY at Stony BrookStony Brook, NY10$10.4 million0$0
University of Missouri-ColumbiaColumbia, MO13$10.2 million0$0
George Mason UniversityFairfax, VA2$10.2 million0$0
University of California-Santa BarbaraSanta Barbara, CA6$10 million0$0
Children's Research InstituteWashington, DC5$9.2 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD6$9.2 million0$0
University of ChicagoChicago, IL4$9.2 million0$0
L2 Diagnostics, LLCNew Haven, CT13$9.1 million0$0
Brandeis UniversityWaltham, MA5$9.1 million0$0
Case Western Reserve UniversityCleveland, OH6$8.8 million0$0
Michigan State UniversityEast Lansing, MI8$8.6 million0$0
Texas Biomedical Research InstituteSan Antonio, TX6$8.4 million0$0
Iowa State UniversityAmes, IA16$8.2 million0$0
Thomas Jefferson UniversityPhiladelphia, PA5$8.2 million0$0
University of MontanaMissoula, MT7$8.1 million0$0
University of Illinois at ChicagoChicago, IL5$8.1 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX6$8 million0$0
Biomedical Research InstituteRockville, MD1$7.9 million0$0
Vanderbilt UniversityNashville, TN9$7.9 million0$0
Texas A&m Agrilife ResearchCollege Station, TX12$7.8 million0$0
The University of Central Florida Board of TrusteesOrlando, FL4$7.8 million0$0
Portland State UniversityPortland, OR3$7.7 million0$0
University of FloridaGainesville, FL9$7.7 million0$0
George Washington UniversityWashington, DC5$7.3 million0$0
Hawaii Biotech, Inc.Honolulu, HI4$7.2 million0$0
Kansas State UniversityManhattan, KS7$7.2 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH2$7.2 million0$0
University of ArizonaTucson, AZ7$7 million0$0
University of South Carolina at ColumbiaColumbia, SC3$6.6 million0$0
Aldatu Biosciences, Inc.Watertown, MA2$6.5 million0$0
Integral MolecularPhiladelphia, PA2$6.4 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025859$452,768,5850$0
2024914$476,069,0530$0
2023904$457,637,0230$0
2022969$511,263,8160$0
20211,022$513,132,0510$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 13 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 3 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 1,645 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 1,645 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 1,645 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 1,645 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 1,645 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 1,645 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 1,645 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 1,645 awards here

Updated November 4, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-04). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.