Data / Research funding / Vascular Contributions to Cognitive Impairment and Dementia (VCID)
Vascular Contributions to Cognitive Impairment and Dementia (VCID): 790 NIH awards ($1.9B) to 179 organizations
790 NIH awards ($1.9B) in the NIH spending category Vascular Contributions to Cognitive Impairment and Dementia (VCID), to 179 organizations, read 2026-11-04. NIH fiscal years 2021 to 2025.
SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.
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The 500 largest of 790 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project | NIH | National Institute on Aging | 2022 to 2025 | $66,521,567 | September 1, 2022 | August 31, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| ADRC Consortium for Clarity in ADRD Research Through Imaging | NIH | National Institute on Aging | 2023 to 2024 | $60,357,563 | September 15, 2023 | August 31, 2028 | JOHNSON, STERLING C | reporter.nih.gov |
| Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium | NIH | National Institute on Aging | 2021 to 2025 | $37,497,984 | September 30, 2021 | August 31, 2026 | HOHMAN, TIMOTHY J | reporter.nih.gov |
| Cognitive training to reduce incidence of cognitive impairment in older adults | NIH | National Institute on Aging | 2021 to 2024 | $37,326,564 | February 1, 2021 | January 31, 2027 | O'BRIEN, JENNIFER LEE | reporter.nih.gov |
| US POINTER Neuroimaging Ancillary Study | NIH | National Institute on Aging | 2021 to 2025 | $24,762,483 | August 1, 2019 | March 31, 2027 | LANDAU, SUSAN M | reporter.nih.gov |
| Metformin in Alzheimer's dementia Prevention (MAP) | NIH | National Institute on Aging | 2021 to 2025 | $24,224,790 | August 15, 2019 | April 30, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| Wisconsin Registry for Alzheimer's Prevention | NIH | National Institute on Aging | 2023 to 2025 | $21,491,270 | June 1, 2023 | February 29, 2028 | JOHNSON, STERLING C | reporter.nih.gov |
| Unraveling the earliest phases of vascular cognitive impairment and dementia using CADASIL--a monogenic form of small vessel cerebrovascular disease | NIH | National Institute on Aging | 2021 to 2025 | $21,188,740 | September 30, 2021 | August 31, 2027 | PAULSEN, JANE S | reporter.nih.gov |
| Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-Old | NIH | National Institute on Aging | 2022 to 2025 | $20,680,832 | September 15, 2017 | June 30, 2027 | WHITMER, RACHEL A | reporter.nih.gov |
| Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease | NIH | National Institute on Aging | 2022 to 2025 | $17,997,906 | May 15, 2022 | January 31, 2028 | GONZALEZ, HECTOR M | reporter.nih.gov |
| Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal) | NIH | National Institute on Aging | 2021 to 2025 | $17,112,209 | August 15, 2018 | May 31, 2029 | HUGHES, TIMOTHY M. | reporter.nih.gov |
| Offspring Study of Mechanisms for Racial Disparities in Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $17,095,138 | September 1, 2016 | May 31, 2027 | MANLY, JENNIFER JAIE | reporter.nih.gov |
| Diabetes and brain amyloid in middle aged Hispanics | NIH | National Institute on Aging | 2021 to 2025 | $16,383,484 | September 1, 2015 | May 31, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic Transitions | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $16,244,011 | September 24, 2001 | August 31, 2026 | JUDD, SUZANNE E | reporter.nih.gov |
| Alzheimer's Disease Research Centers | NIH | National Institute on Aging | 2021 to 2025 | $14,719,450 | September 1, 2020 | March 31, 2030 | CHUI, HELENA CHANG | reporter.nih.gov |
| Integrative Pathways to Cognitive, Affective, and Brain Health | NIH | National Institute on Aging | 2022 to 2025 | $14,488,542 | September 30, 2022 | August 31, 2028 | RYFF, CAROL D. | reporter.nih.gov |
| Mild Cognitive Impairment: A Prospective Community Study | NIH | National Institute on Aging | 2021 to 2025 | $14,337,476 | September 1, 2005 | April 30, 2026 | GANGULI, MARY | reporter.nih.gov |
| Study of Healthy Aging in African Americans | NIH | National Institute on Aging | 2023 to 2025 | $14,240,222 | January 1, 2017 | May 31, 2028 | WHITMER, RACHEL A | reporter.nih.gov |
| MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $14,117,524 | April 1, 2019 | September 30, 2026 | GUSTAFSON, DEBORAH R. | reporter.nih.gov |
| Vanderbilt Memory & Aging Project | NIH | National Institute on Aging | 2021 to 2025 | $14,019,775 | March 15, 2011 | March 31, 2027 | JEFFERSON, ANGELA L. | reporter.nih.gov |
| Epidemiological and Genetic Investigations of Blood-Based Biomarkers for Alzheimer's Disease in the Multiethnic, Washington Heights, Inwood, Columbia Aging Project (WHICAP) | NIH | National Institute on Aging | 2021 to 2025 | $13,310,071 | June 1, 2021 | March 31, 2027 | MAYEUX, RICHARD P | reporter.nih.gov |
| ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028 | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $13,305,831 | July 7, 2010 | March 31, 2029 | CORESH, JOSEF | reporter.nih.gov |
| MIND DIET AND DEMENTIA PREVENTION IN ISCHEMIC STROKE PATIENTS | NIH | National Institute on Aging | 2021 to 2025 | $13,186,351 | September 1, 2020 | May 31, 2027 | AGGARWAL, NEELUM T. | reporter.nih.gov |
| Testing Hypothesized Pathways Linking Infection, Physical Activity, Apoe Genotype, And Biological Sex To Low Dementia Prevalence And Reduced Brain Atrophy In Two Native American Populations | NIH | National Institute on Aging | 2022 to 2025 | $12,690,286 | April 15, 2017 | April 30, 2027 | KAPLAN, HILLARD S | reporter.nih.gov |
| Exploring Cognitive Aging Using Reference Ability Neural Networks | NIH | National Institute on Aging | 2021 to 2025 | $12,167,937 | September 1, 2011 | June 30, 2027 | STERN, YAAKOV | reporter.nih.gov |
| I3C DECADE: Developmental Epidemiology of Childhood Cardiovascular Exposures and Alzheimer’s Dementia | NIH | National Institute on Aging | 2022 to 2025 | $11,889,015 | July 1, 2022 | April 30, 2028 | MACLEHOSE, RICHARD F | reporter.nih.gov |
| Estrogens, Cardiometabolic Health, and Female Cognitive Aging | NIH | National Institute on Aging | 2022 to 2025 | $11,521,268 | March 1, 2022 | February 28, 2027 | DANIEL, JILL M | reporter.nih.gov |
| Sleep in Neurocognitive Aging and Alzheimers Research (SANAR) | NIH | National Institute on Aging | 2021 to 2025 | $11,494,462 | February 1, 2021 | January 31, 2027 | RAMOS, ALBERTO RAFAEL | reporter.nih.gov |
| Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population Study | NIH | National Institute on Aging | 2021 to 2025 | $11,418,675 | September 1, 2021 | May 31, 2027 | RAJAN, KUMAR B. | reporter.nih.gov |
| Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $11,402,108 | September 30, 2004 | May 31, 2027 | BARNES, LISA L | reporter.nih.gov |
| VCID Biomarkers Coordinating Center | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $10,493,954 | September 30, 2016 | June 30, 2027 | GREENBERG, STEVEN M | reporter.nih.gov |
| Vermont Center for Cardiovascular and Brain Health | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $10,185,844 | August 6, 2020 | May 31, 2026 | CUSHMAN, MARY | reporter.nih.gov |
| Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility | NIH | National Institute on Aging | 2021 to 2024 | $9,901,034 | May 1, 2021 | February 28, 2026 | REDLINE, SUSAN S. | reporter.nih.gov |
| Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid and Tau in Older Adults (IPAT-study) | NIH | National Institute on Aging | 2022 to 2025 | $9,488,371 | August 1, 2022 | July 31, 2027 | ZHANG, RONG | reporter.nih.gov |
| BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a Trial | NIH | National Institute on Aging | 2021 to 2025 | $9,481,336 | February 15, 2021 | November 30, 2026 | HANLEY, DANIEL F | reporter.nih.gov |
| The San Antonio Heart and Mind Study | NIH | National Institute on Aging | 2023 to 2025 | $9,286,743 | July 1, 2023 | March 31, 2029 | SATIZABAL, CLAUDIA L | reporter.nih.gov |
| African Americans Fighting Alzheimer’s in Midlife (AA-FAIM) | NIH | National Institute on Aging | 2021 to 2025 | $9,250,399 | August 1, 2016 | November 30, 2027 | GLEASON, CAREY E | reporter.nih.gov |
| Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort | NIH | National Institute on Aging | 2021 to 2025 | $9,240,061 | August 1, 2017 | December 31, 2027 | YASSA, MICHAEL A | reporter.nih.gov |
| Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions | NIH | National Institute on Aging | 2021 to 2025 | $8,654,669 | July 1, 2021 | June 30, 2027 | TEMPLE, SALLY | reporter.nih.gov |
| P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India | NIH | National Institute on Aging | 2024 to 2025 | $8,548,820 | September 15, 2024 | August 31, 2029 | NARAYAN, KABAYAM M VENKAT | reporter.nih.gov |
| Race / Ethncicity, Hypertension and Prevention of VCID and Stroke after Intracerebral Hemmorrhage | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $8,210,604 | February 1, 2016 | July 31, 2027 | ROSAND, JONATHAN | reporter.nih.gov |
| THE NIH PRECISION BRAIN HEALTH NETWORK: Open and Inclusive Measurement of Neuropsychological Change for AD/ADRD Primary Prevention Trials | NIH | National Institute on Aging | 2025 | $7,948,867 | August 1, 2025 | July 31, 2030 | SLIWINSKI, MARTIN J | reporter.nih.gov |
| ERICH-GENE | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $7,768,356 | August 1, 2010 | June 30, 2025 | DEMEL, STACIE | reporter.nih.gov |
| The POINTER Neurovascular Ancillary Study | NIH | National Institute on Aging | 2021 to 2024 | $7,761,498 | April 15, 2020 | December 31, 2025 | BRINKLEY, TINA E | reporter.nih.gov |
| Vietnamese Insights into Cognitive Aging Program (VIP) | NIH | National Institute on Aging | 2021 to 2025 | $7,598,841 | February 15, 2021 | May 31, 2026 | MEYER, OANH L | reporter.nih.gov |
| Look AHEAD Sleep: Sleep-disordered breathing, circadian rest/activity rhythms, and the risk of Alzheimer's disease and related dementias in Look AHEAD | NIH | National Institute on Aging | 2021 to 2025 | $7,592,411 | August 15, 2021 | May 31, 2027 | UDEH-MOMOH, CHINEDU THERESA | reporter.nih.gov |
| REpeated ASseSsmEnt of SurvivorS in ICH (REASSESS ICH) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $7,516,765 | January 1, 2022 | December 31, 2027 | ZIAI, WENDY C | reporter.nih.gov |
| Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience | NIH | National Institute on Aging | 2021 to 2024 | $7,413,273 | September 15, 2020 | May 31, 2025 | SESHADRI, SUDHA | reporter.nih.gov |
| CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimers Disease | NIH | National Institute on Aging | 2021 to 2025 | $7,389,501 | January 15, 2021 | December 31, 2026 | RAO, STEPHEN MARK | reporter.nih.gov |
| Predictors of Altered CNS Structure, Function, and Connectomics in the Elderly using a Health Disparities Framework | NIH | National Institute on Aging | 2022 to 2025 | $7,350,257 | February 15, 2022 | November 30, 2027 | COHEN, ANN D. | reporter.nih.gov |
| Leveraging the 24-hour movement paradigm to preserve cognitive function and prevent Alzheimer's disease: The Multi-Ethnic Study of Atherosclerosis (MESA) 24H-ACT Study | NIH | National Institute on Aging | 2021 to 2024 | $7,263,372 | May 1, 2021 | April 30, 2026 | DIAZ, KEITH M | reporter.nih.gov |
| The VETSA Longitudinal MRI Twin Study of Aging (VETSA MRI 4) | NIH | National Institute on Aging | 2022 to 2025 | $7,252,240 | June 1, 2022 | March 31, 2027 | ELMAN, JEREMY A | reporter.nih.gov |
| A Pragmatic Trial of the UCSF Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $6,593,404 | September 15, 2022 | August 31, 2027 | POSSIN, KATHERINE LAUREL | reporter.nih.gov |
| Extracranial Carotid Atherosclerosis Contributions to Cognitive Impairment and Alzheimer's Disease Risk | NIH | National Institute on Aging | 2021 to 2025 | $6,475,434 | August 15, 2021 | May 31, 2027 | WEINKAUF, CRAIG C | reporter.nih.gov |
| The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center study | NIH | National Institute on Aging | 2021 to 2024 | $6,442,962 | June 15, 2020 | March 31, 2025 | VERGHESE, JOE | reporter.nih.gov |
| Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman Primates | NIH | National Institute on Aging | 2025 | $6,424,607 | September 15, 2025 | September 14, 2029 | BAXTER, MARK G | reporter.nih.gov |
| Contributions of stress reactivity to risk of Alzheimer's disease and related dementia's in a community-based cohort | NIH | National Institute on Aging | 2021 to 2025 | $6,416,931 | September 30, 2021 | May 31, 2027 | KERSHAW, KIARRI N | reporter.nih.gov |
| Validation of the Remote Cognitive Aging and Alzheimer’s Disease REsearch (R-CARE) Toolbox for Diverse Populations | NIH | National Institute on Aging | 2023 to 2025 | $6,381,700 | August 15, 2023 | May 31, 2028 | LIPTON, RICHARD B. | reporter.nih.gov |
| Cerebral small vessel disease burden and racial disparity in vascular cognitive impairment and Alzheimer’s disease and its related dementias | NIH | National Institute on Aging | 2021 to 2025 | $6,336,090 | September 15, 2021 | May 31, 2027 | HYACINTH, HYACINTH IDU | reporter.nih.gov |
| A Life Course Approach to Integrating Trauma and Cognitive Aging: A Cohort of 9/11 Responders | NIH | National Institute on Aging | 2021 to 2024 | $6,329,240 | May 15, 2015 | April 30, 2026 | CLOUSTON, SEAN | reporter.nih.gov |
| Validation of Biomarkers of Small Vessel Injury in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,258,167 | September 29, 2021 | July 31, 2026 | ROSENBERG, GARY ALLEN | reporter.nih.gov |
| Washington University University of Texas Southwestern VCID Consortium Site | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,224,729 | September 29, 2021 | July 31, 2026 | LEE, JIN-MOO | reporter.nih.gov |
| IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia | NIH | National Institute on Aging | 2021 to 2023 | $6,168,197 | April 15, 2020 | March 31, 2024 | HAY, MEREDITH | reporter.nih.gov |
| The University of Kentucky MarkVCID Biomarker Validation Cohort: Development of a Toolbox to Advance VCID Interventional Studies | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,120,000 | September 29, 2021 | July 31, 2026 | JICHA, GREGORY A | reporter.nih.gov |
| MarkVCID Validation in the General Community | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,100,999 | September 23, 2021 | July 31, 2026 | PETERSEN, RONALD C | reporter.nih.gov |
| VCID CWOW: Identifying Novel Targets to Treat Cerebral Amyloid Angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $5,949,022 | September 18, 2024 | August 31, 2027 | HOWELL, GARETH R | reporter.nih.gov |
| URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related Dementias | NIH | National Institute on Aging | 2021 to 2024 | $5,941,036 | September 1, 2019 | May 31, 2026 | NELSON, LONNIE A. | reporter.nih.gov |
| PNA5: A Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Vascular Dementia and Alzheimer's Disease Related Dementia: an FDA required Toxicology Study | NIH | National Institute on Aging | 2023 to 2025 | $5,906,221 | September 1, 2023 | August 31, 2027 | HAY, MEREDITH | reporter.nih.gov |
| Examining Effects of Intensive BP Control on MCI/Dementia and Plasma Biomarker Trajectories by AD Pathology: Elucidating neuroprotective effects in the racially and ethnically diverse SPRINT trial | NIH | National Institute on Aging | 2025 | $5,789,766 | September 30, 2025 | June 30, 2030 | BRESS, ADAM P | reporter.nih.gov |
| Cerebral tau deposition and comorbid cerebrovascular disease across the Alzheimer's disease continuum in Mexican Americans | NIH | National Institute on Aging | 2024 to 2025 | $5,730,361 | August 15, 2024 | August 31, 2029 | HABES, MOHAMAD | reporter.nih.gov |
| Brain pathologies, reserve and cognition in aging and dementia | NIH | National Institute on Aging | 2022 to 2025 | $5,694,414 | March 1, 2009 | March 31, 2027 | TOMASZEWSKI-FARIAS, SARAH E | reporter.nih.gov |
| Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural Population | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $5,484,212 | March 6, 2020 | March 21, 2025 | GALVIN, JAMES E | reporter.nih.gov |
| Vascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathology | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $5,423,836 | September 19, 2024 | August 31, 2027 | YANG, ANDREW CHRIS | reporter.nih.gov |
| Environmental Exposures and Brain Health | NIH | National Institute on Aging | 2025 | $5,164,012 | September 1, 2025 | August 31, 2029 | JAMES, PETER | reporter.nih.gov |
| Microbial Impact on NeuroDegeneration in Alzheimer's Dementia: MIND-AD | NIH | National Institute on Aging | 2021 to 2025 | $5,121,493 | September 30, 2021 | May 31, 2027 | SPIRA, ADAM PETER | reporter.nih.gov |
| A Precision Medicine Approach for the Study of Targetable Pathways in Vascular Dementia | NIH | National Institute on Aging | 2022 to 2025 | $5,086,657 | February 1, 2022 | November 30, 2026 | GOATE, ALISON M | reporter.nih.gov |
| Brain Health and Ethnic Disparities in ADRD Risk: The Case of Arab Americans | NIH | National Institute on Aging | 2021 to 2025 | $5,040,162 | April 1, 2021 | March 31, 2027 | ANTONUCCI, TONI CLAUDETTE | reporter.nih.gov |
| Multi-scale and multi-modality imaging of neuropathology in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,964,481 | September 22, 2023 | August 31, 2028 | GE, YULIN | reporter.nih.gov |
| Characterizing Cognitive Decline in Late Life Depression: The ADNI-D Project | NIH | National Institute of Mental Health | 2022 to 2025 | $4,842,533 | August 1, 2013 | May 31, 2027 | MACKIN, ROBERT SCOTT | reporter.nih.gov |
| Vasculo-neuronal pathophysiological interface in Alzheimer’s and Atherosclerosis | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,815,513 | September 18, 2024 | August 31, 2027 | IRUELA-ARISPE, M. LUISA | reporter.nih.gov |
| Novel retinal higher-order capillary hemodynamics imaging for detecting cerebral small vessel disease | NIH | Office of the Director, National Institutes of Health | 2024 to 2025 | $4,719,171 | September 15, 2024 | September 14, 2027 | WANG, JIANHUA | reporter.nih.gov |
| Defining the molecular spectrum of white matter vascular lesions | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,693,249 | September 17, 2024 | August 31, 2027 | HINMAN, JASON D | reporter.nih.gov |
| An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,539,313 | September 22, 2023 | August 31, 2028 | VAN DER KOUWE, ANDRE JAN WILLEM | reporter.nih.gov |
| Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,511,697 | January 1, 2019 | December 31, 2026 | NELSON, MARK T | reporter.nih.gov |
| A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC Collaboration | NIH | National Institute on Aging | 2023 to 2025 | $4,445,528 | September 15, 2017 | June 30, 2028 | SACHDEV, PERMINDER S | reporter.nih.gov |
| Cognitive Impairment and Dementia, Vascular Brain Injury, and Atrial Myopathy: Implications for Prevention of Alzheimer's Disease-Related Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,390,219 | September 20, 2023 | August 31, 2026 | CHEN, LIN YEE | reporter.nih.gov |
| Precursors of Stroke Incidence and Prognosis | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,368,194 | December 1, 1981 | August 31, 2028 | ROMERO, JOSE RAFAEL | reporter.nih.gov |
| VCID Center Without Walls for Understanding and Leveraging Small Vessel Cerebrovascular Disease Mechanisms in ADRD | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,361,625 | September 24, 2024 | August 31, 2027 | LEE, JIN-MOO | reporter.nih.gov |
| Spreading Tau Pathology in Non-Amnestic Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $4,306,312 | July 1, 2018 | June 30, 2028 | PHILLIPS, JEFFREY S | reporter.nih.gov |
| Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $4,141,255 | September 30, 2024 | August 31, 2029 | GOLDSTEIN, LEE E. | reporter.nih.gov |
| Structural and diffusion changes of perivascular space in aging, cognitive decline and Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $4,101,683 | September 5, 2021 | June 30, 2027 | CHOUPAN, JEIRAN | reporter.nih.gov |
| Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,093,112 | September 30, 2016 | July 31, 2027 | LU, HANZHANG | reporter.nih.gov |
| Vascular Pathology in Early and Asymptomatic Cerebral Amyloid Angiopathy | NIH | National Institute on Aging | 2021 to 2025 | $3,993,325 | September 30, 2014 | March 31, 2027 | VISWANATHAN, ANAND | reporter.nih.gov |
| Building an unbiased pooled cohort for the study of lifecourse social and vascular determinants of Alzheimer's Disease and Related Disorders | NIH | National Institute on Aging | 2021 to 2025 | $3,985,562 | June 15, 2021 | March 31, 2027 | ZEKI AL HAZZOURI, ADINA | reporter.nih.gov |
| Preeclampsia and the Brain: Small vessel disease and cognitive function in early midlife | NIH | National Institute on Aging | 2022 to 2025 | $3,960,160 | February 1, 2022 | November 30, 2026 | CATOV, JANET M | reporter.nih.gov |
| Burden and change in Alzheimers disease neuropathology in aging World Trade Center responders | NIH | National Institute on Aging | 2021 to 2025 | $3,952,934 | March 15, 2021 | February 28, 2027 | CLOUSTON, SEAN | reporter.nih.gov |
| Synergistic white matter injury from diesel exhaust particulate and chronic cerebral hypoperfusion exposures: Interaction between the Nogo/NgR1 receptor pathway and extravascular fibrinogen toxicity | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,929,367 | September 20, 2022 | August 31, 2027 | MACK, WILLIAM J | reporter.nih.gov |
| Depression treatment and Aβ dynamics: A study of Alzheimer’s disease risk | NIH | National Institute on Aging | 2021 to 2025 | $3,865,122 | August 15, 2021 | July 31, 2027 | POMARA, NUNZIO | reporter.nih.gov |
| Validation of Imaging and Blood-based Small Vessel VCID Biomarkers in Multiethnic Population | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,859,697 | September 30, 2021 | July 31, 2027 | WANG, DANNY JJ | reporter.nih.gov |
| PRE3BAD: Preclinical Research on Emerging Environmental Exposures, Brain Aging, and Dementia | NIH | National Institute on Aging | 2024 to 2025 | $3,859,319 | September 30, 2024 | August 31, 2029 | CAMPEN, MATTHEW J | reporter.nih.gov |
| Perivascular fibroblasts, vascular fibrosis, and their contributions to cerebral amyloid angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,851,096 | September 19, 2022 | July 31, 2027 | LIPPMANN, ETHAN | reporter.nih.gov |
| Menopausal Vasomotor Symptoms and Brain Aging in Women | NIH | National Institute on Aging | 2021 to 2025 | $3,849,407 | August 15, 2016 | June 30, 2027 | THURSTON, REBECCA C | reporter.nih.gov |
| Resilience to Cognitive Decline and Resistance to Alzheimer's Disease and Related Neurodegenerative Diseases in Individuals from Colombia with Autosomal Dominant Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $3,821,618 | August 15, 2023 | July 31, 2026 | QUIROZ, YAKEEL T. | reporter.nih.gov |
| Alzheimer's Disease Pathology in a Primate Model | NIH | National Institute on Aging | 2021 to 2025 | $3,764,077 | February 15, 2021 | January 31, 2027 | HOPKINS, WILLIAM D | reporter.nih.gov |
| Digital Biomarkers for Vascular Cognitive Decline in Patients with Minor Stroke | NIH | National Institute on Aging | 2022 to 2025 | $3,752,944 | September 10, 2022 | August 31, 2027 | MARSH, ELISABETH BREESE | reporter.nih.gov |
| Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF) | NIH | National Institute on Aging | 2021 to 2025 | $3,724,610 | September 1, 2021 | May 31, 2027 | MATHEW, JOSEPH P | reporter.nih.gov |
| Digital Accessible Remote Olfactory Mediated Health Assessments forPreclinical AD | NIH | National Institute on Aging | 2021 to 2025 | $3,718,193 | September 30, 2018 | June 30, 2027 | REINEKE, SEAN | reporter.nih.gov |
| TRP channels as fundamental sensors of the cerebral microcirculation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,709,945 | February 1, 2021 | July 31, 2024 | EARLEY, SCOTT | reporter.nih.gov |
| Reducing African Americans' Alzheimer's Disease Risk Through Exercise-MCI Cohort (RAATE-MCI) | NIH | National Institute on Aging | 2021 to 2025 | $3,689,143 | July 1, 2020 | March 31, 2027 | NEWTON, ROBERT LEE | reporter.nih.gov |
| Lymphatics-Glymphatics in CNS Fluid Homeostasis | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,644,017 | April 1, 2021 | March 31, 2026 | BENVENISTE, HELENE D | reporter.nih.gov |
| Molecular and Physiological Mechanisms of Hypertensive Cerebral Microangiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,627,088 | July 1, 2020 | April 30, 2026 | GUROL, MAHMUT EDIP | reporter.nih.gov |
| Immunovascular interactions in postoperative delirium superimposed on dementia (DSD). | NIH | National Institute on Aging | 2022 to 2025 | $3,624,866 | September 15, 2022 | August 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Advanced MRI studies of cerebrovascular and lymphatic abnormalities in LRRK2 mouse models of Parkinson's disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,536,285 | April 1, 2021 | March 31, 2027 | SMITH, WANLI W | reporter.nih.gov |
| Assessing the Role of Sex-Specific Genetic Drivers of Cerebrovascular Disease in the Alzheimer's Disease Brain | NIH | National Institute on Aging | 2025 | $3,531,593 | September 1, 2025 | August 31, 2029 | DUMITRESCU, LOGAN C | reporter.nih.gov |
| SPRINT MIND 2020 | NIH | National Institute on Aging | 2021 to 2023 | $3,485,934 | June 15, 2017 | May 31, 2025 | REBOUSSIN, DAVID M | reporter.nih.gov |
| Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,480,622 | September 29, 2021 | July 31, 2027 | ARFANAKIS, KONSTANTINOS | reporter.nih.gov |
| Construction of an Integrated Immune - Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $3,475,569 | September 20, 2019 | May 31, 2024 | TSAI, LI-HUEI | reporter.nih.gov |
| Role of Fibrinogen in Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,431,479 | April 1, 2018 | July 31, 2028 | STRICKLAND, SIDNEY | reporter.nih.gov |
| The Role of PAI-1 in Cerebral Microvascular Dysfunction and the Development of Alzheimer’s Disease Neuropathology | NIH | National Institute on Aging | 2021 to 2025 | $3,397,256 | September 1, 2021 | June 30, 2027 | LAWRENCE, DANIEL A | reporter.nih.gov |
| Metabolic and neural activity normalization by cerebral blood flow increase in AD/ADRD models | NIH | National Institute on Aging | 2023 to 2025 | $3,391,148 | April 15, 2023 | January 31, 2028 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Sex Differences in Inflammation Across the Lifespan | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,353,112 | May 1, 2023 | April 30, 2031 | MCCULLOUGH, LOUISE D. | reporter.nih.gov |
| BRain Aging and Cognition in Epilepsy (BRACE): A longitudinal investigation of vascular, genetic, and biomarker risk profiles in elderly patients with epilepsy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,346,371 | September 1, 2021 | February 28, 2027 | MCDONALD, CARRIE R | reporter.nih.gov |
| Multiethnic Validation of VCID Biomarkers in South Texas | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,325,938 | September 30, 2021 | July 31, 2027 | SATIZABAL, CLAUDIA L | reporter.nih.gov |
| Locus Coeruleus Imaging Markers in Preclinical Alzheimers disease, Cerebrovascular Disease and Cognitive Decline | NIH | National Institute on Aging | 2024 to 2025 | $3,322,482 | April 1, 2023 | March 31, 2029 | NATION, DANIEL A | reporter.nih.gov |
| Innate Immunity Stimulation Effects on Biomarkers, Cognition, and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAA | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,321,272 | July 15, 2022 | June 30, 2027 | SCHOLTZOVA, HENRIETA | reporter.nih.gov |
| Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $3,312,473 | September 5, 2021 | June 30, 2026 | DING, YU-SHIN | reporter.nih.gov |
| Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and Inattention | NIH | National Institute on Aging | 2022 to 2025 | $3,308,332 | August 1, 2022 | April 30, 2027 | DEVINNEY, MICHAEL JOSEPH | reporter.nih.gov |
| Role of GPR39 in Aging-Related Vascular Cognitive Impairment (VCI) | NIH | National Institute on Aging | 2022 to 2025 | $3,287,439 | September 15, 2022 | August 31, 2027 | ALKAYED, NABIL J | reporter.nih.gov |
| Microglia-Amyloid interactions in delirium superimposed on dementia | NIH | National Institute on Aging | 2021 to 2025 | $3,246,663 | September 15, 2017 | December 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Role of endothelium in pathogenesis of cerebral amyloid angiopathy | NIH | National Institute on Aging | 2021 to 2025 | $3,245,352 | September 1, 2021 | June 30, 2026 | KATUSIC, ZVONIMIR S | reporter.nih.gov |
| ApoE4, Neurovascular Injury and Cognitive Impairment | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,244,519 | April 1, 2022 | March 31, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Cerebral hemodynamic impairment in symptomatic and asymptomatic Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,221,061 | February 1, 2022 | January 31, 2027 | QIU, DEQIANG | reporter.nih.gov |
| Vascular contribution to white matter lesions and motor dysfunction in AD and ADRD | NIH | National Institute on Aging | 2022 to 2025 | $3,210,645 | September 15, 2022 | August 31, 2027 | AHN, HYUNG JIN | reporter.nih.gov |
| RCT Targeting Cognition in Early Alzheimer's Disease by Improving Sleep with Trazodone (Rest) | NIH | National Institute on Aging | 2021 to 2024 | $3,203,115 | September 15, 2021 | August 31, 2026 | GREENBERG, BARRY DAVID | reporter.nih.gov |
| Characterization of relationship between tau pathology and neurodegeneration in Alzheimer's disease using multimodal imaging | NIH | National Institute on Aging | 2022 to 2025 | $3,200,041 | April 15, 2022 | January 31, 2027 | DAS, SANDHITSU | reporter.nih.gov |
| Effects of vascular risk factors on risk for dementia and stroke after late-onset epilepsy (EpilepsyCOG) | NIH | National Institute on Aging | 2022 to 2025 | $3,188,533 | July 1, 2022 | March 31, 2027 | CHOI, HYUNMI | reporter.nih.gov |
| Novel Imaging and Biofluid Biomarkers of Small Vessel Cerebrovascular Disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,180,774 | September 29, 2021 | July 31, 2027 | KRAMER, JOEL H | reporter.nih.gov |
| Cerebrovascular Remodeling and Neurodegenerative Changes in Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,178,600 | February 1, 2022 | January 31, 2027 | ZHANG, YANHANG KATHERINE | reporter.nih.gov |
| Contributions of modifiable physical attributes to cognitive and brain aging | NIH | National Institute on Aging | 2021 to 2025 | $3,167,967 | May 15, 2021 | April 30, 2027 | HAYES, SCOTT M | reporter.nih.gov |
| Carotid Revascularization and Medical Management for Asymptomatic CarotidStenosis Trial - Hemodynamics (CREST-H) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,153,445 | May 15, 2017 | July 31, 2027 | MARSHALL, RANDOLPH S | reporter.nih.gov |
| POINTER-zzz: Sleep Ancillary to U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $3,144,541 | August 15, 2019 | May 31, 2025 | BAKER, LAURA D. | reporter.nih.gov |
| Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementia | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $3,134,584 | January 1, 2018 | December 31, 2023 | NICHOLS, COLIN G | reporter.nih.gov |
| Investigating Resistance and Resilience Mechanisms in Alzheimer’s Disease | NIH | National Institute on Aging | 2021 to 2025 | $3,131,976 | September 15, 2017 | February 29, 2028 | VEMURI, PRASHANTHI | reporter.nih.gov |
| Alzheimer's Abeta, Tau, Apolipoproteins and Blood-brain barrier | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,119,037 | September 1, 1995 | February 28, 2026 | YASSINE, HUSSEIN N | reporter.nih.gov |
| Longitudinal MRI Investigation of Traumatic Microvascular Injury | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,116,729 | February 15, 2022 | January 31, 2027 | WARE, JEFFREY B | reporter.nih.gov |
| Impairment of Ischemia-induced Vascular Functions by PS1 FAD Mutants | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,116,100 | January 15, 2021 | December 31, 2025 | GEORGAKOPOULOS, ANASTASIOS | reporter.nih.gov |
| Alzheimer's Disease Hallmark Pathology and Associated Inflammation in the Retina | NIH | National Institute on Aging | 2021 to 2025 | $3,113,565 | April 1, 2018 | June 30, 2028 | KORONYO-HAMAOUI, MAYA | reporter.nih.gov |
| Recovery of StrokE - Longitudinal Assessment With Neuroimaging (ROSE LAWN) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,104,674 | December 15, 2020 | November 30, 2025 | WOO, DANIEL | reporter.nih.gov |
| Advanced MR Imaging of Olfactory Impairment in Prodromal Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $3,102,717 | May 1, 2020 | February 28, 2026 | HUA, JUN | reporter.nih.gov |
| Immune Cells in Alzheimer’s Disease and Related Dementias in the Jackson Heart Study | NIH | National Institute on Aging | 2022 to 2025 | $3,079,808 | March 1, 2022 | November 30, 2026 | RAFFIELD, LAURA M | reporter.nih.gov |
| Covert Cerebrovascular Disease Detected by Artificial Intelligence (C2D2AI): A Platform for Pragmatic Evidence Generation for Stroke and Dementia Prevention | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,076,281 | February 1, 2023 | January 31, 2026 | KENT, DAVID M | reporter.nih.gov |
| Novel Volumetric Optical Microscopy to Unravel Cerebral Microvascular Architecture and the Role in Functional Neuroimaging in Human Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,069,316 | August 1, 2022 | July 31, 2027 | WANG, HUI | reporter.nih.gov |
| Efflux Route Responses of Cerebral Waste Clearance During Progression of Alzheimer’s Disease | NIH | National Institute on Aging | 2025 | $3,062,355 | September 15, 2025 | August 31, 2029 | JIANG, QUAN | reporter.nih.gov |
| The Amylin Dyshomeostasis Hypothesis of Vascular Contributions to Cognitive Impairment and Dementia (VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,056,084 | April 1, 2020 | March 31, 2026 | DESPA, FLORIN | reporter.nih.gov |
| Intracranial arterial compliance, cerebral blood flow, and dementia risk in older adults with type 2 diabetes | NIH | National Institute on Aging | 2021 to 2024 | $3,038,302 | May 1, 2020 | February 28, 2026 | BANGEN, KATHERINE | reporter.nih.gov |
| Aging Research Characterizing Health Equity via Social determinants (ARCHES) | NIH | National Institute on Aging | 2021 to 2024 | $3,033,223 | September 1, 2021 | May 31, 2026 | BABULAL, GANESH M | reporter.nih.gov |
| Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimer’s Disease | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,032,391 | May 15, 2021 | April 30, 2026 | TSAI, LI-HUEI | reporter.nih.gov |
| Gas-free cerebrovascular reactivity (CVR) MRI in vascular cognitive impairment | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,984,490 | August 16, 2021 | July 31, 2027 | LIU, PEIYING | reporter.nih.gov |
| Safety and Tolerability Studies for an Anti-Fibrin P2 Monoclonal Antibody for the Treatment of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $2,970,786 | September 30, 2021 | August 31, 2024 | KANTOR, AARON B | reporter.nih.gov |
| Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communities | NIH | National Institute on Aging | 2022 to 2025 | $2,961,521 | August 15, 2022 | April 30, 2027 | MANTYH, WILLIAM G | reporter.nih.gov |
| Air pollution and early signs of dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,959,713 | September 30, 2022 | August 31, 2027 | HUELS, ANKE | reporter.nih.gov |
| Brain signature of SARS-CoV-2 Infection and its impact on long-term cognitive functioning in older adults | NIH | National Institute on Aging | 2022 to 2025 | $2,954,828 | July 1, 2022 | June 30, 2027 | SCHIFITTO, GIOVANNI | reporter.nih.gov |
| Development and Evaluation of Portable Compendium of Psychophysical and Physiological Tests for Alzheimer's Disease and Related Dementias (ADRD) | NIH | National Institute on Aging | 2023 to 2025 | $2,947,375 | August 1, 2023 | April 30, 2026 | NWAOKOBIA, CHARLES CHIEDU | reporter.nih.gov |
| Global Brain Health Predictors of Post-Stroke Sensorimotor Recovery using AI-Enhanced Clinical MRIs | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,942,690 | April 1, 2020 | June 30, 2029 | LIEW, SOOK-LEI | reporter.nih.gov |
| Stroke Connectome MRI Biomarkers for VCID Risk Assessment | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,928,784 | April 1, 2022 | March 31, 2027 | NAIR, VEENA A | reporter.nih.gov |
| Longitudinal multi-omic biomarkers for neurocognitive decline prior to dementia onset | NIH | National Institute on Aging | 2024 to 2025 | $2,904,500 | September 30, 2024 | June 30, 2029 | HARRIS, SARAH ELIZABETH | reporter.nih.gov |
| Dietary Sodium, Neurovascular Dysfunction and Cerebrovascular Risk | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,895,400 | December 1, 2015 | June 30, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Roles of Gray Matter Brain Aging and Small Vessel Disease in AD Pathophysiology | NIH | National Institute on Aging | 2024 to 2025 | $2,872,909 | March 1, 2005 | February 28, 2027 | AIZENSTEIN, HOWARD J | reporter.nih.gov |
| Multiethnic machine learning brain signatures of ADRD | NIH | National Institute on Aging | 2022 to 2025 | $2,860,890 | September 1, 2022 | June 30, 2027 | HABES, MOHAMAD | reporter.nih.gov |
| Elucidating Molecular Drivers of Aging and Alzheimer's Disease via Multimodal Imaging Mass Spectrometry | NIH | National Institute on Aging | 2022 to 2025 | $2,856,050 | September 1, 2022 | June 30, 2027 | SPRAGGINS, JEFFREY M | reporter.nih.gov |
| Auracle: An AI-Enabled Telecare System to Support the Independence and Safety of Individuals with AD/ADRD and Other Dementias | NIH | National Institute on Aging | 2021 to 2023 | $2,851,310 | September 1, 2021 | August 31, 2025 | FAUCI, MARK A | reporter.nih.gov |
| The relationship between ocus-coeruleus-norepinephrine network and neurovascular coupling in health and disease | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,813,759 | August 15, 2025 | July 31, 2029 | TRAN, CAM HA THAI | reporter.nih.gov |
| An Epidemiologic Study of Disparities in Sleep and Cognition in Older Adults (DISCO) | NIH | National Institute on Aging | 2021 to 2023 | $2,797,984 | July 1, 2019 | March 31, 2024 | KNUTSON, KRISTEN | reporter.nih.gov |
| Pathological mechanisms of white matter hyperintensities | NIH | National Institute on Aging | 2021 to 2024 | $2,796,704 | September 1, 2021 | January 15, 2025 | RANE LEVENDOVSZKY, SWATI | reporter.nih.gov |
| Modeling and Therapeutic Approaches for Genetic Vasculopathies | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,784,876 | September 20, 2022 | July 31, 2027 | MUSOLINO, PATRICIA L | reporter.nih.gov |
| Investigating the Microvascular Mechanisms of O2 Supply-Demand Mismatch in Small Vessel Disease using Novel High-Resolution Optical Imaging | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,778,545 | May 1, 2020 | April 30, 2026 | SAKADZIC, SAVA | reporter.nih.gov |
| BBB Dysfunction in Post-Stroke Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,776,180 | September 15, 2022 | August 31, 2027 | BUCKWALTER, MARION S | reporter.nih.gov |
| Favorable cardiovascular health, connectome integrity, and ADRD clinical outcomes and pathologic underpinnings in a diverse cohort. | NIH | National Institute on Aging | 2022 to 2025 | $2,728,963 | August 1, 2022 | July 31, 2028 | LAMAR, MELISSA | reporter.nih.gov |
| Metabolic and Vascular Factors in tau pathogenesis | NIH | National Institute on Aging | 2021 to 2024 | $2,720,466 | September 15, 2020 | May 31, 2025 | FRAUTSCHY, SALLY ANN | reporter.nih.gov |
| Metabolic and Hormonal Mechanisms of VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,707,906 | April 15, 2019 | August 31, 2029 | ZULOAGA, KRISTEN LEANNE | reporter.nih.gov |
| Role of Endothelial K+ Channels in Age-Related Dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,707,384 | May 1, 2022 | April 30, 2027 | BEHRINGER, ERIK J. | reporter.nih.gov |
| Establishment of a Human Microphysiological System to Elucidate Cellular Mechanisms Underlying Vulnerability to AD | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,683,965 | May 1, 2025 | April 30, 2028 | YOUNG-PEARSE, TRACY L | reporter.nih.gov |
| Enhancing gamma band response to improve working memory in individuals with mild cognitive impairment | NIH | National Institute on Aging | 2021 to 2024 | $2,658,625 | April 1, 2020 | March 31, 2026 | SINGH, FIZA | reporter.nih.gov |
| Underlying Mechanisms in CADASIL | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,643,847 | April 20, 2021 | March 31, 2026 | IRUELA-ARISPE, M. LUISA | reporter.nih.gov |
| 24-hour Activity Cycles to Optimize Cognitive Resilience to Alzheimer's Disease in African Americans: The Jackson Heart Study | NIH | National Institute on Aging | 2021 to 2023 | $2,629,362 | September 15, 2020 | May 31, 2026 | GABRIEL, KELLEY PETTEE | reporter.nih.gov |
| Development and validation of novel models for cerebral small vessel disease and vascular cognitive impairment | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,624,637 | September 18, 2019 | August 31, 2025 | GOULD, DOUGLAS | reporter.nih.gov |
| Diversity Supplement for Jenny Lutshumba | NIH | National Institute on Aging | 2023 to 2024 | $2,600,455 | September 1, 2023 | August 31, 2026 | STOWE, ANN MARIE | reporter.nih.gov |
| Cerebral Microvascular Signaling and Neurovascular Coupling: An Integrated Approach to Investigate VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,597,866 | August 1, 2021 | June 30, 2026 | TSOUKIAS, NIKOLAOS MICHAEL | reporter.nih.gov |
| Sex differences in the contribution of cerebrovascular injury and immune activation to neurocognitive impairment in HIV infection | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,594,711 | May 15, 2022 | February 28, 2027 | CHOW, FELICIA C. | reporter.nih.gov |
| Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study | NIH | National Institute on Aging | 2021 to 2024 | $2,594,669 | April 15, 2020 | March 31, 2026 | MURABITO, JOANNE M | reporter.nih.gov |
| Human 3D Neuro-Vascular Interaction and Meningeal Lymphatic Models with Application to Alzheimer’s Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,593,927 | May 1, 2021 | April 30, 2026 | KAMM, ROGER D | reporter.nih.gov |
| Blood-Brain Barrier Disruption as a Biomarker for Perioperative Neurocognitive Disorder:Cognitive Recovery after Elective Surgery | NIH | National Institute on Aging | 2021 to 2024 | $2,592,630 | May 1, 2019 | February 28, 2026 | DAIELLO, LORI A | reporter.nih.gov |
| Using AI on Routine Clinical and Imaging Data from Acute Stroke Encounter to Predict Post-Stroke Vascular Contributions to Cognitive Impairment (AI - RESPECT) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $2,575,013 | September 1, 2024 | July 31, 2027 | HU, XIAO | reporter.nih.gov |
| Investigating the Role and the therapeutic potential of Perlecan in experimental vascular dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,573,724 | June 12, 2024 | April 30, 2027 | BIX, GREGORY JAYE | reporter.nih.gov |
| Transferring Speed of Processing Gains to Everyday Cognitive Tasks after Stroke | NIH | National Institute on Aging | 2021 to 2024 | $2,570,286 | September 5, 2021 | August 31, 2025 | USWATTE, GITENDRA | reporter.nih.gov |
| Pericyte control of capillary perfusion in the Alzheimer's disease brain | NIH | National Institute on Aging | 2023 to 2025 | $2,557,000 | April 15, 2023 | January 31, 2028 | SHIH, ANDY Y | reporter.nih.gov |
| Neuropathology and inflammation in a nonhuman primate model of insulin resistance/metabolic syndrome | NIH | National Institute on Aging | 2024 to 2025 | $2,556,565 | February 15, 2024 | November 30, 2028 | HAVEL, PETER J | reporter.nih.gov |
| Impact of SARS-CoV-2 on the cerebrovasculature as a risk factor for VCID: Role of Wnt/beta-catenin | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,549,080 | August 11, 2025 | July 31, 2029 | LUTZ, SARAH ELIZABETH | reporter.nih.gov |
| Citalopram as a posterior cortical protective therapy in Parkinson disease | NIH | National Institute on Aging | 2021 to 2024 | $2,545,093 | August 15, 2020 | April 30, 2026 | KOTAGAL, VIKAS | reporter.nih.gov |
| Non-Invasive Imaging Markers to Elicit the Role of Vascular Involvement in Alzheimer’s Disease | NIH | National Institute on Aging | 2022 to 2025 | $2,534,541 | February 15, 2022 | January 31, 2027 | JOHNSON, KEVIN MICHAEL | reporter.nih.gov |
| The role of brain border-associated macrophages in aging and cerebral amyloid angiopathy | NIH | National Institute on Aging | 2022 to 2025 | $2,534,516 | January 15, 2022 | December 31, 2026 | LAFAILLE, JUAN | reporter.nih.gov |
| BRAIN HEALTH TOGETHER: A LIVE-STREAMING GROUP-BASED DIGITAL PROGRAM | NIH | National Institute on Aging | 2021 to 2023 | $2,534,108 | September 30, 2021 | November 30, 2024 | BENJAMIN, CYNTHIA LOUISE | reporter.nih.gov |
| Effects of NAD restoration on neurovascular coupling in community dwelling older adults | NIH | National Institute on Aging | 2022 to 2025 | $2,531,921 | August 15, 2022 | April 30, 2027 | YABLUCHANSKIY, ANDRIY | reporter.nih.gov |
| Activated protein C mechanisms of brain white matter protection and new therapies for brain white matter ischemic injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,531,008 | July 15, 2020 | April 30, 2026 | MACK, WILLIAM J | reporter.nih.gov |
| Vascular Contributions to Cognitive Impairment after Adverse Pregnancy Outcomes: the nuMoM2b-Heart Health Study | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,523,397 | July 15, 2021 | June 30, 2027 | MILLER, ELIZA C | reporter.nih.gov |
| Sex-specific cognitive expression and risk in preclinical Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2023 | $2,519,693 | September 15, 2019 | May 31, 2025 | BANKS, SARAH | reporter.nih.gov |
| Effects of global brain health on sensorimotor recovery after stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,507,791 | April 1, 2020 | March 31, 2026 | LIEW, SOOK-LEI | reporter.nih.gov |
| Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older Adults | NIH | National Institute on Aging | 2022 to 2025 | $2,505,518 | September 30, 2022 | June 30, 2027 | GRODSTEIN, FRANCINE | reporter.nih.gov |
| Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,499,958 | April 1, 2022 | August 31, 2027 | LEIGH, RICHARD | reporter.nih.gov |
| Early Detection of Mild Cognitive Impairment, Alzheimer's Disease and Other Dementias using EHR | NIH | National Institute on Aging | 2021 to 2025 | $2,490,121 | September 15, 2020 | May 31, 2027 | SOHN, SUNGHWAN | reporter.nih.gov |
| Imaging Cerebral Small Vessels in Vascular Cognitive Impairment and Dementia (VCID) | NIH | National Institute on Aging | 2023 | $2,487,668 | September 1, 2023 | August 31, 2026 | WANG, DANNY JJ | reporter.nih.gov |
| Gene therapy for disorders of the extracellular matrix | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,481,348 | April 1, 2023 | March 31, 2026 | GOULD, DOUGLAS | reporter.nih.gov |
| Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE) | NIH | National Institute on Aging | 2021 to 2025 | $2,465,845 | February 15, 2019 | November 30, 2025 | NEWTON, ROBERT LEE | reporter.nih.gov |
| Leveraging Electronic Health Records and artificial IntelligeNce to improve Dementia Screening and early Detection in primary care (LEARN-DSD) | NIH | National Institute on Aging | 2023 to 2025 | $2,462,815 | September 21, 2023 | July 31, 2028 | RAZAVIAN, NARGES | reporter.nih.gov |
| Brain lymphatic activation for craniosynostosis and Alzheimer’s disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,461,369 | June 1, 2024 | May 31, 2027 | CHEN, JIANFU | reporter.nih.gov |
| Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging - AD/ADRD | NIH | National Institute on Aging | 2021 to 2023 | $2,458,774 | April 1, 2019 | January 31, 2025 | KACENA, MELISSA A | reporter.nih.gov |
| Velocity-Selective Arterial Spin Labeling based Perfusion Mapping for Alzheimer's disease | NIH | National Institute on Aging | 2023 | $2,448,470 | May 1, 2023 | April 30, 2026 | QIN, QIN | reporter.nih.gov |
| Vascular contributions to HIV-associated Neurocognitive Disorders (HAND) | NIH | National Institute on Aging | 2022 to 2024 | $2,441,402 | August 1, 2022 | July 31, 2027 | GUTIERREZ, JOSE | reporter.nih.gov |
| Development of perivascular space mapping toolset as a diagnostic aid for Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $2,439,170 | August 1, 2024 | July 31, 2027 | CHOUPAN, JEIRAN | reporter.nih.gov |
| Role of Microglia in Cerebral Small Vessel Disease (CSVD)/Vascular Cognitive Impairment (VCI) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,430,570 | July 15, 2022 | June 30, 2027 | WEINSTEIN, JONATHAN R | reporter.nih.gov |
| Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation | NIH | National Institute on Aging | 2021 to 2023 | $2,427,515 | August 1, 2019 | April 30, 2026 | BOWERS, DAWN | reporter.nih.gov |
| Inspiring Healthy Engagement and Learning for Vascular Dementia (I-HEAL) | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,421,629 | September 1, 2025 | August 31, 2029 | CABAN-HOLT, ALLISON MERCEDES | reporter.nih.gov |
| Human cerebral blood flow regulation: sex, mechanism, and stress differences | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,414,516 | June 1, 2020 | May 31, 2025 | SCHRAGE, WILLIAM G | reporter.nih.gov |
| REACH-EpiVCID | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,403,545 | August 5, 2024 | July 31, 2027 | ANDERSON, CHRISTOPHER DAVID | reporter.nih.gov |
| Mechanisms of APOE-Induced Preclinical Alzheimer's Pathophysiology in Human Olfactory System | NIH | National Institute on Aging | 2021 to 2023 | $2,398,805 | August 15, 2019 | May 31, 2025 | NWULIA, EVARISTUS A | reporter.nih.gov |
| Brain capillary endothelial cell energetics and neurovascular uncoupling in dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,398,590 | September 24, 2024 | August 31, 2026 | DABERTRAND, FABRICE | reporter.nih.gov |
| Role of TREX1 in age-related hereditary leukoencephalopathy | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,381,292 | September 20, 2023 | June 30, 2028 | MINER, JONATHAN J | reporter.nih.gov |
| Type 2 Diabetes Mellitus and Vascular Contributions to Cognitive Impairment and Dementia (T2DM-VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,380,018 | September 18, 2024 | August 31, 2027 | LEVINE, DEBORAH ALLISON | reporter.nih.gov |
| Mechanisms of Vasomotion-mediated Perivascular Clearance in Cerebral Amyloid Angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,376,712 | August 1, 2022 | July 31, 2027 | GREENBERG, STEVEN M | reporter.nih.gov |
| Alzheimer Pathology and Neurovascular Dysfunction | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,375,220 | July 1, 1998 | December 31, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Genetic and Environmental Risk Factors for Hemorrhagic Stroke – V | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,374,719 | September 12, 1997 | July 31, 2027 | WOO, DANIEL | reporter.nih.gov |
| Investigating the role of Alpha5Beta1 integrin in cognitive dysfunction | NIH | National Institute on Aging | 2023 to 2024 | $2,373,215 | April 1, 2023 | March 31, 2026 | BIX, GREGORY JAYE | reporter.nih.gov |
| Identifying A Skeleton-Derived Factor for Vascular Aging | NIH | National Institute on Aging | 2021 to 2025 | $2,368,758 | April 1, 2021 | December 31, 2026 | WAN, MEI | reporter.nih.gov |
| Epigenetic Aging Cognitive Function and Exercise in Older Adults | NIH | National Institute on Aging | 2024 | $2,358,537 | September 1, 2024 | August 31, 2027 | CONLEY, YVETTE P | reporter.nih.gov |
| SPAK-NKCC1 complex and the blood-CSF barrier dysregulation in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,353,206 | September 8, 2025 | June 30, 2029 | SUN, DANDAN | reporter.nih.gov |
| CSF Clearance in Sporadic Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $2,348,572 | August 15, 2019 | April 30, 2025 | LI, YI | reporter.nih.gov |
| Imaging of cerebral microvascular pulsatility in cerebral small vessel disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,346,270 | August 1, 2024 | June 30, 2027 | YAN, LIRONG | reporter.nih.gov |
| Adverse Cerebrovascular Responses to Antibodies Targeting Beta-Amyloid | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,342,415 | June 1, 2024 | May 31, 2027 | CRIBBS, DAVID HASTINGS | reporter.nih.gov |
| COVID-19-related blood-brain barrier and microstructural brain injury; Sex differences and synergy with Alzheimer's disease risk | NIH | National Institute on Aging | 2023 to 2025 | $2,337,162 | December 15, 2022 | November 30, 2027 | REAS, EMILIE T. | reporter.nih.gov |
| Common mechanistic biomarkers of vascular and neuro-degeneration | NIH | National Institute on Aging | 2023 to 2025 | $2,330,263 | January 1, 2023 | December 31, 2027 | LIU, YONGMEI | reporter.nih.gov |
| Building a Platform for Precision Anesthesia for the Geriatric Surgical Patient | NIH | National Institute on Aging | 2022 to 2024 | $2,319,904 | September 1, 2020 | August 31, 2025 | DROVER, DAVID RAYMOND | reporter.nih.gov |
| Map Paravascular Fluid Dynamic Signatures of Key Aging and AD Processes Using Dynamics Diffusion-Weighted Imaging | NIH | National Institute on Aging | 2023 | $2,317,887 | September 15, 2023 | August 31, 2026 | WEN, QIUTING | reporter.nih.gov |
| CAPSTONE: Central And Peripheral STrOke inflammatioN with Exosomes | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,297,999 | July 19, 2022 | June 30, 2027 | WALSH, KYLE BRENDAN | reporter.nih.gov |
| Investigating and targeting apolipoprotein E4 in Down syndrome-associated Alzheimer's disease | NIH | National Institute on Aging | 2023 | $2,282,487 | July 15, 2023 | June 30, 2026 | JOHNSON, NOAH RAY | reporter.nih.gov |
| The effect of circadian rhythm disruptions on the angiogenic response to hypoperfusion in the AD brain | NIH | National Institute on Aging | 2023 to 2025 | $2,278,875 | May 1, 2023 | January 31, 2028 | ARAI, KEN | reporter.nih.gov |
| Simultaneous EEG/fMRI to disentangle neural and vascular mechanisms of Alzheimer's disease pathology | NIH | National Institute on Aging | 2022 to 2025 | $2,274,229 | August 15, 2022 | July 31, 2027 | SITNIKOVA, TATIANA | reporter.nih.gov |
| Role of cerebral vasculature in brain ischemia in HIV infection | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,266,377 | September 15, 2014 | July 31, 2026 | TOBOREK, MICHAL | reporter.nih.gov |
| Exercise Mimetics for Dementia and Alzheimer's Disease | NIH | National Institute on Aging | 2023 | $2,262,938 | February 1, 2023 | January 31, 2026 | BURRIS, THOMAS P | reporter.nih.gov |
| Elucidating microvascular contributions to cognitive impairment at single-cell resolution | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,262,548 | December 3, 2024 | June 30, 2028 | YANG, ANDREW CHRIS | reporter.nih.gov |
| Reproductive history and later-life brain health: The Bogalusa Heart Study | NIH | National Institute on Aging | 2023 | $2,258,605 | September 1, 2023 | August 31, 2026 | HARVILLE, EMILY WHEELER | reporter.nih.gov |
| Midlife cardiovascular stress physiology and preclinical cerebrovascular disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,248,100 | July 1, 2023 | June 30, 2028 | GIANAROS, PETER J | reporter.nih.gov |
| GPR39 as a Therapeutic Target in Aging-Related Vascular Cognitive Impairment and Dementia | NIH | National Institute on Aging | 2023 | $2,244,471 | September 1, 2023 | August 31, 2026 | ALKAYED, NABIL J | reporter.nih.gov |
| Diversity Supplement to 1RF1 NS128963 | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $2,240,090 | August 15, 2022 | June 30, 2025 | NELSON, MARK T | reporter.nih.gov |
| Neurological and digital correlates of cognition in Older Mandarin-speaking Adults | NIH | National Institute on Aging | 2023 | $2,236,070 | December 15, 2022 | November 30, 2025 | HU, WILLIAM TZU-LUNG | reporter.nih.gov |
| Identification of plasma lipoprotein proteins and lipids as biomarkers of innate-immunity and vascular contributions to Alzheimer's disease and Alzheimer's disease-related dementias in older adults | NIH | National Institute on Aging | 2023 | $2,232,476 | June 1, 2023 | May 31, 2026 | LI, DANNI | reporter.nih.gov |
| Transcranial Magnetic Stimulation for MCI: A Phase II Dose-Response Study | NIH | National Institute on Aging | 2023 to 2025 | $2,230,431 | May 15, 2023 | April 30, 2028 | BENITEZ, ANDREANA | reporter.nih.gov |
| Novel Biomarkers of Small Vessel Contributions to Vascular Cognitive Impairment and Dementia (VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,230,406 | August 15, 2019 | June 30, 2025 | DETRE, JOHN A | reporter.nih.gov |
| Imaging Advancements in Small Vessel and CSF Flow Pathophysiology of Pre-clinical Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $2,224,084 | April 15, 2019 | January 31, 2026 | IBRAHIM, TAMER S | reporter.nih.gov |
| Identifying the Genetic Etiology of Neuropathology for Alzheimer Disease and Related Dementias | NIH | National Institute on Aging | 2021 to 2023 | $2,223,810 | June 15, 2019 | March 31, 2026 | BEECHAM, GARY WAYNE | reporter.nih.gov |
| Adaptive Neuromodulation of Working Memory Networks in Aging and Dementia | NIH | National Institute on Aging | 2022 to 2024 | $2,223,690 | September 15, 2022 | May 31, 2027 | DAVIS, SIMON W | reporter.nih.gov |
| An Imaging Repository for the Cerebrovascular Disease Knowledge Portal (iCDKP) | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,195,574 | September 1, 2023 | August 31, 2028 | ROSAND, JONATHAN | reporter.nih.gov |
| Glymphatic impairment as a crucial factor in particulate matter exposure related development of Alzheimer's disease pathology | NIH | National Institute on Aging | 2023 to 2025 | $2,180,411 | September 1, 2023 | May 31, 2028 | HUSSAIN, RASHAD | reporter.nih.gov |
| Early Detection of Vascular Dysfunction Using Biomarkers from Lagrangian Carotid Strain Imaging | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,172,540 | July 15, 2020 | June 30, 2025 | VARGHESE, TOMY | reporter.nih.gov |
| IL-6 Trans-signaling increases vulnerability to Postoperative Cognitive Decline in Aging and Alzheimers Disease | NIH | National Institute on Aging | 2024 to 2025 | $2,167,099 | September 15, 2024 | May 31, 2029 | MAZE, MERVYN | reporter.nih.gov |
| The role of blood and brain 5-hydroxymethylcytosine in linking vascular risk factors to ADRD in older White and Black persons | NIH | National Institute on Aging | 2024 to 2025 | $2,159,342 | August 15, 2021 | July 31, 2027 | ARVANITAKIS, ZOE | reporter.nih.gov |
| Fine particulate matter exposure and small cerebrovascular inflammation | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,151,314 | September 19, 2023 | August 31, 2026 | LIU, ZHENGUO | reporter.nih.gov |
| Elucidating the Role of Endothelial Dysfunction in Alzheimer Disease: Towards A New Data-Driven Disease Model | NIH | National Institute on Aging | 2023 | $2,140,130 | September 1, 2023 | August 31, 2026 | TARAWNEH, RAWAN | reporter.nih.gov |
| Metabolic Interventions for Sleep, Anesthesia-related Neurocognitive Disorders and Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $2,137,648 | June 15, 2022 | February 28, 2027 | NEHS, CHRISTA JOY | reporter.nih.gov |
| Neurovascular Consequences of Non-Pulsatile Flow from Left Ventricular Assist Devices | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,135,855 | January 1, 2022 | December 31, 2026 | WILLEY, JOSHUA ZEBADIAH | reporter.nih.gov |
| Post-stroke normal appearing white matter diffusion properties and cognitive trajectories across age | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,126,325 | February 1, 2023 | January 31, 2028 | INGO, CARSON J | reporter.nih.gov |
| Cerebrospinal fluid exchange in Alzheimer's disease characterized by advanced MRI techniques | NIH | National Institute on Aging | 2023 to 2025 | $2,119,671 | December 15, 2022 | November 30, 2027 | XU, JIADI | reporter.nih.gov |
| Contribution of Cerebral Iron Load to Cognitive Function in Older Adults with High Risk to Develop Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $2,115,944 | September 15, 2020 | May 31, 2026 | QIAO, YE | reporter.nih.gov |
| Early Life Cardiovascular Disease Risk Factors, Epigenetic Age Acceleration, and Alzheimer's Disease Related Brain Health | NIH | National Institute on Aging | 2023 to 2025 | $2,111,649 | April 1, 2022 | January 31, 2027 | KELLY, TANIKA NICOLE | reporter.nih.gov |
| AQP4 and glymphatic function in post-stroke recovery | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,108,706 | July 1, 2022 | June 30, 2027 | YU, XIN | reporter.nih.gov |
| Investigating Pathways from Adverse Pregnancy Outcomes to Alzheimer's Disease and Related Dementias: the nuMoM2b-Brain Study | NIH | National Institute on Aging | 2024 | $2,090,311 | July 15, 2024 | February 28, 2025 | MILLER, ELIZA C | reporter.nih.gov |
| Dementia Risk Prediction Pooling Project | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,083,833 | September 30, 2020 | August 31, 2025 | ALLEN, NORRINA BAI | reporter.nih.gov |
| Psychosocial Stress-Induced Vascular Contributions To Cognitive Impairment And Alzheimer's Disease: The Role of Xanthine Oxidase | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,079,585 | September 1, 2021 | July 31, 2025 | CHANTLER, PAUL D | reporter.nih.gov |
| Ex Vivo Imaging of the Aging Brain to Discover Morphology/Pathology Associations | NIH | National Institute on Aging | 2023 | $2,077,693 | April 15, 2023 | March 31, 2026 | YUSHKEVICH, PAUL A. | reporter.nih.gov |
| Sleep-dependent mechanisms of improving cerebral blood flow and reducing Alzheimer's disease progression by photobiomodulation with near-infrared light | NIH | National Institute on Aging | 2023 to 2025 | $2,074,140 | May 15, 2023 | January 31, 2028 | GERASHCHENKO, DMITRY | reporter.nih.gov |
| Oligodendrocyte Progenitors and Mechanisms of Human Vascular White Matter Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,066,705 | July 15, 2019 | April 30, 2026 | BACK, STEPHEN ARTHUR | reporter.nih.gov |
| tPA and Cerebrovascular Regulation in a Model of ß-amyloid Pathology | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,065,728 | April 1, 2018 | March 31, 2028 | PARK, LAIBAIK | reporter.nih.gov |
| Predictors and Biomarkers for VCID versus Cognitive Recovery after Stroke Thrombectomy in Rural Appalachia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,063,623 | April 15, 2023 | March 31, 2028 | HARP, JORDAN PATRICK | reporter.nih.gov |
| THE SENDEP STUDY: LINKING MOLECULAR SENESCENCE CHANGES TO DEPRESSION AND COGNITIVE IMPAIRMENT IN LATE LIFE | NIH | National Institute of Mental Health | 2021 to 2023 | $2,057,113 | February 15, 2019 | December 31, 2024 | DINIZ, BRENO SATLER | reporter.nih.gov |
| A New Molecular Target to Enhance Poststroke Cognitive Recovery | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,054,575 | May 1, 2023 | April 30, 2028 | LI, GUOHONG | reporter.nih.gov |
| Stroke Minimization through Additive Anti-atherosclerotic Agents in Routine Treatment II Study | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,050,132 | September 1, 2022 | August 31, 2027 | OVBIAGELE, BRUCE | reporter.nih.gov |
| A Drug Discovery Platform to Prioritize Development of Natural Product Neuromodulators for Treating Cognitive Impairment | NIH | National Institute on Aging | 2024 to 2025 | $2,019,940 | December 1, 2023 | March 31, 2027 | BROWN, JEFFREY M. | reporter.nih.gov |
| Astrocyte regulation of cerebral blood flow at the intersection of ischemia and Alzheimer's disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,018,852 | September 22, 2023 | August 31, 2028 | MISHRA, ANUSHA | reporter.nih.gov |
| Inflammation and delayed cognitive dysfunction after stroke | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,016,915 | March 15, 2023 | February 28, 2026 | DOYLE, KRISTIAN PAUL | reporter.nih.gov |
| iPSC-derived Neurovascular Organoids | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,012,834 | April 15, 2020 | March 31, 2026 | LIPPMANN, ETHAN | reporter.nih.gov |
| Astrocytes as governing pathological drivers of neurovascular dysfunction in AD | NIH | National Institute on Aging | 2021 to 2025 | $2,005,277 | March 1, 2017 | February 29, 2028 | BACSKAI, BRIAN J | reporter.nih.gov |
| Microglial-Neurovascular Dynamics and Regulation of Neurovascular Structure and Function | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,994,764 | August 1, 2021 | May 31, 2026 | EYO, UKPONG BASSEY | reporter.nih.gov |
| Non-contrast MR imaging of blood-brain-barrier permeability in Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2023 | $1,991,093 | May 1, 2020 | April 30, 2025 | LU, HANZHANG | reporter.nih.gov |
| The blood-brain barrier and Alzheimer pathology | NIH | National Institute on Aging | 2023 to 2025 | $1,986,144 | September 30, 2023 | May 31, 2028 | JAGUST, WILLIAM J. | reporter.nih.gov |
| Immunometabolic regulation after CNS injury | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $1,975,262 | September 21, 2023 | August 31, 2026 | DHANDAPANI, KRISHNAN M. | reporter.nih.gov |
| Modifying endothelial Piezo 1 function to improve brain perfusion in AD/ADRD | NIH | National Institute on Aging | 2023 to 2025 | $1,974,645 | June 1, 2023 | February 29, 2028 | MARRELLI, SEAN P | reporter.nih.gov |
| Lifespan and Cardiovascular Health Effects on The Brain in Humans and Great Ape | NIH | National Institute on Aging | 2024 to 2025 | $1,966,730 | September 17, 2024 | May 31, 2029 | HOF, PATRICK R | reporter.nih.gov |
| Neurovascular circadian oscillation in health and Alzheimer's disease | NIH | National Institute on Aging | 2023 | $1,966,145 | May 1, 2023 | April 30, 2026 | DANEMAN, RICHARD | reporter.nih.gov |
| Chronic Alcohol, Dementia, and CNS Fluid Homeostasis | NIH | National Institute on Alcohol Abuse and Alcoholism | 2022 to 2025 | $1,959,740 | September 20, 2022 | August 31, 2027 | MASON, GRAEME F | reporter.nih.gov |
| Kerala-Einstein Aging Study | NIH | National Institute on Aging | 2021 to 2023 | $1,956,088 | August 1, 2011 | May 31, 2025 | VERGHESE, JOE | reporter.nih.gov |
| Extracellular Mitochondria Transfer in Gray and White Matter for Ameliorating Sensorimotor and Cognitive Deficits After Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,948,682 | February 15, 2022 | January 31, 2027 | HAYAKAWA, KAZUHIDE | reporter.nih.gov |
| Imaging of brain oxygen extraction fraction in vascular contributions to dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,944,714 | April 15, 2023 | March 31, 2028 | FAN, AUDREY PEIWEN | reporter.nih.gov |
| Deciphering the role of junctional adhesion molecule-A in neutrophil-driven inflammatory response in Alzheimer disease | NIH | National Institute on Aging | 2023 to 2025 | $1,930,446 | August 15, 2023 | April 1, 2028 | ANDJELKOVIC-ZOCHOWSKA, ANUSKA V. | reporter.nih.gov |
| APOE Allele Switching as a Therapeutic Approach for Alzheimer's Disease | NIH | National Institute on Aging | 2023 to 2025 | $1,914,100 | December 1, 2022 | November 30, 2027 | JOHNSON, LANCE ALLEN | reporter.nih.gov |
| A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $1,904,995 | September 3, 2020 | August 31, 2025 | HUGHES, CHRISTOPHER C. W. | reporter.nih.gov |
| Epidemiology of blood pressure responses to perturbations: Correlates and prognosis for vascular risk, end-organ damage, cognitive aging and preclinical Alzheimer's disease | NIH | National Institute on Aging | 2023 to 2025 | $1,880,104 | June 1, 2022 | February 28, 2027 | RAMACHANDRAN, VASAN | reporter.nih.gov |
| Large artery stiffness and cerebrovascular dysfunction: Implications for cognitive impairment and neuropathology | NIH | National Institute on Aging | 2021 to 2024 | $1,864,502 | April 15, 2020 | February 28, 2026 | WALKER, ASHLEY ELIZABETH | reporter.nih.gov |
| Modeling Alzheimer's Disease Related Dementias in the Marmoset | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $1,851,822 | September 16, 2019 | August 31, 2025 | LEE, KUO-FEN | reporter.nih.gov |
| The Role of Pericytes in Brain Hypoperfusion in Alzheimer's Disease Development | NIH | National Institute on Aging | 2023 to 2025 | $1,849,689 | April 15, 2023 | January 31, 2028 | FAN, HONGKUAN | reporter.nih.gov |
| Airborne metals, neurodegeneration, and dementia in the Adult Changes in Thought study | NIH | National Institute of Environmental Health Sciences | 2023 to 2025 | $1,847,274 | September 15, 2023 | June 30, 2028 | SUH, HELEN | reporter.nih.gov |
| Enlarged Perivascular Spaces as Markers of Vascular and Alzheimer pathology: predictors, pathophysiology and clinical consequences | NIH | National Institute on Aging | 2021 to 2023 | $1,846,394 | August 1, 2019 | April 30, 2026 | ROMERO, JOSE RAFAEL | reporter.nih.gov |
| Leveraging omics data to understand sleep health and its consequences among diverse Hispanics/Latinos | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,844,341 | July 1, 2022 | June 30, 2027 | SOFER, TAMAR | reporter.nih.gov |
| Changes in Cerebrovascular Function with Aging in Normal and AD Brain | NIH | National Institute on Aging | 2021 to 2024 | $1,840,772 | March 1, 2020 | December 31, 2025 | SONTHEIMER, HARALD W | reporter.nih.gov |
| ARCADIA CSI (Cognition and Silent Infarcts) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,817,706 | July 1, 2019 | September 30, 2024 | LANSBERG, MAARTEN G | reporter.nih.gov |
| Capillary control of cerebral blood flow, and its disruption in small vessel disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $1,817,568 | February 1, 2017 | February 28, 2027 | DABERTRAND, FABRICE | reporter.nih.gov |
| Investigating Pathways from Adverse Pregnancy Outcomes to Alzheimer's Disease and Related Dementias: the nuMoM2b-Brain Study | NIH | National Institute on Aging | 2025 | $1,806,846 | July 15, 2024 | April 30, 2029 | MILLER, ELIZA C | reporter.nih.gov |
| The role of microglia Nek6 in myocardial infarction-induced cognitive impairment | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,805,517 | July 1, 2020 | June 30, 2025 | DUTTA, PARTHA | reporter.nih.gov |
| Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,797,545 | February 1, 2022 | January 31, 2027 | SHAH, AMY SANGHAVI | reporter.nih.gov |
| The Effect of Sex Hormones on Cardiometabolic Outcomes in Men and Women with Diabetes: The Look AHEAD (Action for Health in Diabetes) Study | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,796,808 | September 15, 2020 | June 30, 2025 | BENNETT, WENDY LYNET | reporter.nih.gov |
| Proteomic Profiling of Patent Foramen Ovale Related Neurovascular Injury | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $1,795,134 | July 1, 2010 | June 30, 2027 | NING, MINGMING | reporter.nih.gov |
| The role of IGF-1 signaling in vascular smooth muscle cells in age-related vascular cognitive impairment and dementia | NIH | National Institute on Aging | 2021 to 2025 | $1,778,358 | September 30, 2021 | May 31, 2027 | CONLEY, SHANNON M | reporter.nih.gov |
| Premenopausal bilateral oophorectomy and biomarkers of Alzheimer’s and cerebrovascular diseases | NIH | National Institute on Aging | 2025 | $1,775,401 | May 15, 2025 | April 30, 2030 | KANTARCI, KEJAL | reporter.nih.gov |
| Role of impaired cognitive states & risk factors in conversion to mixed dementias | NIH | National Institute on Aging | 2021 to 2023 | $1,771,960 | September 1, 2011 | January 31, 2025 | KRYSCIO, RICHARD J. | reporter.nih.gov |
| Lasting Impacts: Dynamic, Fully Natural Bioprinted 3D Human Neurovascular Biomimetic Model to Study Traumatic Brain Injury Pathophysiology | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,766,629 | September 15, 2021 | December 31, 2026 | MOYA, MONICA LIZET | reporter.nih.gov |
| Cerebral Vascular Redox Regulation in Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,746,383 | July 15, 2023 | April 30, 2028 | STRAUB, ADAM CARL | reporter.nih.gov |
| Progressive Post-Stroke Cognitive Impairment: Mechanisms & Intervention | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $1,745,096 | September 15, 2018 | August 31, 2027 | ERGUL, ADVIYE | reporter.nih.gov |
| Understanding the role of the cerebral microvasculature in brain aging | NIH | National Institute on Aging | 2023 to 2025 | $1,718,194 | August 1, 2023 | April 30, 2028 | RUTKAI-GREEN, IBOLYA | reporter.nih.gov |
| Genetic Architecture of Aging-Related TDP-43 and Mixed Pathology Dementia | NIH | National Institute on Aging | 2023 | $1,714,473 | April 15, 2023 | March 31, 2026 | FARDO, DAVID WILLIAM | reporter.nih.gov |
| Mechanisms underlying Sex differences in Cerebral Amyloid Angiopathy: The Fibrin-Microglia Crosstalk | NIH | National Institute on Aging | 2023 to 2025 | $1,713,060 | April 1, 2023 | March 31, 2029 | MANWANI, BHARTI | reporter.nih.gov |
| Clarifying the association of depressive symptoms with cortico-limbic tau, cerebral blood flow, neurodegeneration, and longitudinal cognitive decline in individuals with mild cognitive impairment | NIH | National Institute on Aging | 2025 | $1,711,908 | April 15, 2025 | March 31, 2030 | MACKIN, ROBERT SCOTT | reporter.nih.gov |
| Systemic and dietary advanced glycation end products in type 2 diabetes-related cognitive decline and incident dementia: effects on Alzheimer's pathology and cerebrovascular disease | NIH | National Institute on Aging | 2021 to 2023 | $1,702,136 | February 1, 2019 | November 30, 2023 | SCHNAIDER BEERI, MICHAL | reporter.nih.gov |
| Alzheimer's Disease-Related Dementia Models by Precision Editing and Relevant Genetic x Environmental Exposures | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $1,699,708 | September 16, 2019 | August 31, 2025 | O'CONNELL, KRISTEN M | reporter.nih.gov |
| Gut Immunity, Neurovascular Dysregulation and Cognitive Impairment | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,695,000 | September 18, 2022 | August 31, 2027 | FARACO, GIUSEPPE | reporter.nih.gov |
| Neuronal and vascular interactions in the CNS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,693,594 | July 15, 2020 | June 30, 2024 | GU, CHENGHUA | reporter.nih.gov |
| Nicotinamide riboside supplementation for treating arterial stiffness and elevated systolic blood pressure in patients with moderate to severe CKD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,693,290 | May 23, 2019 | March 31, 2025 | CHONCHOL, MICHEL BENJAMIN | reporter.nih.gov |
| Neuroinflammatory Mechanisms of Vascular Cognitive Impairment | NIH | National Institute on Aging | 2023 | $1,659,018 | September 15, 2017 | August 31, 2026 | ALKAYED, NABIL J | reporter.nih.gov |
| Mechanisms of cognitive impairment caused by atherosclerosis and red blood cell released ATP | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,653,797 | August 1, 2024 | July 31, 2029 | HE, PINGNIAN | reporter.nih.gov |
| Race/ethnicity and Environmental Stressors: POtential drivers of Dementia and stroke inequities RESPOnD | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,644,642 | July 15, 2024 | June 30, 2029 | PESCADOR JIMENEZ, MARCIA IXCHEL | reporter.nih.gov |
| Microvascular Stress as a Pathway to Neurodegeneration in Alzheimer's | NIH | National Institute on Aging | 2022 to 2025 | $1,641,575 | February 1, 2022 | January 31, 2027 | BENNETT, RACHEL ELISE | reporter.nih.gov |
| Age-related Hypertension and Vascular Cognitive Impairment | NIH | National Institute on Aging | 2022 to 2023 | $1,638,234 | February 1, 2022 | May 31, 2023 | WAINFORD, RICHARD DAVID | reporter.nih.gov |
| Post-stroke Cognitive Impairment and Dementia | NIH | National Institute on Aging | 2024 to 2025 | $1,629,398 | September 15, 2024 | July 31, 2029 | XIAN, YING | reporter.nih.gov |
| Digital Cognitive Assessment of Preclinical Alzheimer's Disease and Related Dementias | NIH | National Institute on Aging | 2024 to 2025 | $1,628,248 | August 1, 2024 | April 30, 2029 | AU, RHODA | reporter.nih.gov |
| Modeling Cerebral Microbleeds and Striatal Brain Iron in Adult Congenital Heart Disease in Relationship to Differential Genetic Risk for Alzheimer Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,626,747 | June 1, 2020 | May 31, 2025 | CESCHIN, RAFAEL C | reporter.nih.gov |
| Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,626,188 | September 15, 2021 | August 31, 2027 | ALOSCO, MICHAEL | reporter.nih.gov |
| Locus Coeruleus Imaging Markers in Preclinical Alzheimers disease, Cerebrovascular Disease and Cognitive Decline | NIH | National Institute on Aging | 2023 | $1,623,978 | April 1, 2023 | July 31, 2023 | NATION, DANIEL A | reporter.nih.gov |
| Understanding and Mitigating Vascular Side-Effects Associated with Anti-Amyloid Immunotherapy | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,615,518 | June 1, 2024 | May 31, 2029 | LEMERE, CYNTHIA A | reporter.nih.gov |
| Gut microbiome-related metabolites and cognitive impairment | NIH | National Institute on Aging | 2024 to 2025 | $1,606,250 | September 15, 2024 | July 31, 2029 | KIMBERLY, WILLIAM TAYLOR | reporter.nih.gov |
| A Squirrel Monkey Model of Alzheimer’s Disease: Developing Behavioral, Blood, and CSF Biomarkers | NIH | National Institute on Aging | 2024 to 2025 | $1,605,066 | September 15, 2021 | May 31, 2027 | HOPKINS, WILLIAM D | reporter.nih.gov |
| Pathophysiological mechanisms of hypoperfusion in mouse models of Alzheimer?s disease and small vessel disease | NIH | National Institute on Aging | 2023 to 2025 | $1,597,303 | May 15, 2023 | January 31, 2028 | WEI, ZHILIANG | reporter.nih.gov |
| Elucidating the Link Between Oral Health and Dementia Subtypes: A Multifaceted Study on the Biological Pathways and Social Determinants | NIH | National Institute on Aging | 2024 to 2025 | $1,594,142 | August 15, 2024 | April 30, 2029 | QI, XIANG | reporter.nih.gov |
| Establishing a Brain Health Index | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,593,534 | January 7, 2023 | April 30, 2027 | THOMAS, ROBERT JOSEPH | reporter.nih.gov |
| Preclinical evaluation of tacrolimus in a canine model of Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $1,593,298 | September 15, 2017 | May 31, 2027 | HEAD, ELIZABETH | reporter.nih.gov |
| An Integrative Computational Multimodal approach to disentangle Pathophysiologic Heterogeneity of age-related White Matter Hyperintensities | NIH | National Institute on Aging | 2024 to 2025 | $1,585,301 | September 1, 2024 | May 31, 2029 | PHUAH, CHIA-LING | reporter.nih.gov |
| Regulation of Flt 1 Splicing by Fibronectin and Integrin Signaling During Aging | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $1,583,383 | September 19, 2023 | August 31, 2026 | MURPHY, PATRICK ANDRIES | reporter.nih.gov |
| Stem Cell-Derived Exosomes, MrgD and Vascular Cognitive Impairment in Aging | NIH | National Institute on Aging | 2021 to 2025 | $1,582,923 | September 15, 2017 | April 30, 2028 | JARAJAPU, YAGNA | reporter.nih.gov |
| Na/H Exchanger in Microglial Metabolism and Function | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,578,265 | February 4, 2005 | June 30, 2027 | SUN, DANDAN | reporter.nih.gov |
| Meningeal Stem Cell Signals for Improving Sensorimotor and Cognitive Outcomes After Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,564,073 | February 1, 2020 | November 30, 2025 | HAYAKAWA, KAZUHIDE | reporter.nih.gov |
| Integrated Cerebral Blood Flow Regulation | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,562,976 | December 1, 2021 | November 30, 2026 | TRAN, CAM HA THAI | reporter.nih.gov |
| Cofilin Signaling in Hemorrhagic Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,560,785 | June 15, 2020 | March 31, 2026 | SHAH, ZAHOOR AHMAD | reporter.nih.gov |
| MenoBrain: A Longitudinal Investigation of Menopause and Brain Health | NIH | National Institute on Aging | 2025 | $1,558,726 | January 1, 2025 | December 31, 2029 | THURSTON, REBECCA C | reporter.nih.gov |
| Peripheral immunity and the aging brain: Studying the relationship of platelet and neutrophil activity with markers of vascular contributions to cognitive decline and dementia | NIH | National Institute on Aging | 2025 | $1,552,000 | September 15, 2025 | May 31, 2030 | RAMOS-CEJUDO, JAIME | reporter.nih.gov |
| Vascular Imaging Biomarker Relationships to Alzheimer’s disease (VIBRA) | NIH | National Institute on Aging | 2024 to 2025 | $1,551,084 | September 15, 2024 | May 31, 2029 | HABES, MOHAMAD | reporter.nih.gov |
| Altered Microglia States and Microglia-Endothelial Cell Axis in Relation to White Matter Disease Progression in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,549,664 | September 18, 2023 | August 31, 2028 | HORSBURGH, KAREN | reporter.nih.gov |
| Physiological imaging markers in vascular contributions to cognitive impairment and dementia (VCID) | NIH | National Institute on Aging | 2024 to 2025 | $1,541,901 | December 5, 2023 | November 30, 2028 | LU, HANZHANG | reporter.nih.gov |
| Stalled capillary flow: a novel mechanism for hypoperfusion in Alzheimer disease | NIH | National Institute on Aging | 2024 to 2025 | $1,537,776 | May 15, 2015 | April 30, 2026 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Adiponectin on cerebrovascular regulation in vascular cognitive impairment and dementia (VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,535,200 | January 1, 2022 | December 31, 2026 | HU, XIAOMING | reporter.nih.gov |
| Effects of the renin angiotensin system on MRI volumetric measures and cognitive function in the Alzheimer's disease process: the LookAHEAD study | NIH | National Institute on Aging | 2022 to 2024 | $1,534,661 | July 1, 2022 | March 31, 2026 | YASAR, SEVIL | reporter.nih.gov |
| Longitudinal impact of midlife cerebrovascular pulsatility on brain tissue integrity and cognitive aging | NIH | National Institute on Aging | 2024 to 2025 | $1,532,721 | September 15, 2024 | May 31, 2029 | MARTENS, CHRISTOPHER | reporter.nih.gov |
| Multimodal in Vivo and Postmortem Analysis of ARIA-Relevant Pathophysiology | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,531,729 | August 1, 2025 | July 31, 2030 | KOFLER, JULIA K | reporter.nih.gov |
| Humanization of a Notch 3 Agonist Antibody for Pre-Clinical Development of a CADASIL Treatment | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,529,075 | January 15, 2021 | December 31, 2025 | ARBOLEDA-VELASQUEZ, JOSEPH | reporter.nih.gov |
| Remote ischemic Conditioning Promotes Cerebrovascular Recovery after Intracerebral Hemorrhage | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,523,768 | September 1, 2020 | July 31, 2025 | DHANDAPANI, KRISHNAN M. | reporter.nih.gov |
| Air pollution and noise exposures in relation to dementia: from brain imaging markers to clinical disease | NIH | National Institute on Aging | 2021 to 2023 | $1,521,542 | February 1, 2020 | July 31, 2025 | WEUVE, JENNIFER | reporter.nih.gov |
| A New Informatics Approach for Detection of Cerebrovascular Abnormalities | NIH | National Library of Medicine | 2022 to 2025 | $1,521,500 | August 15, 2022 | May 31, 2027 | YOUNG, GEOFFREY | reporter.nih.gov |
| Cerebrovascular reactivity as a VCID biomarker in CADASIL | NIH | National Institute on Aging | 2024 to 2025 | $1,521,356 | September 30, 2024 | June 30, 2029 | BARNES, JILL NICOLE | reporter.nih.gov |
| Lymphatic drainage dysfunction in chronic hypertension | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,520,151 | July 15, 2024 | May 31, 2028 | BENVENISTE, HELENE D | reporter.nih.gov |
| Amyloid-β Disruption of Pericyte Control of Capillary Hemodynamics | NIH | National Institute on Aging | 2023 to 2025 | $1,519,812 | April 1, 2023 | March 31, 2028 | GONZALES, ALBERT LOUIS | reporter.nih.gov |
| Protein Arginine Methyltransferases in Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,518,787 | May 1, 2024 | April 30, 2029 | LIN, HUNG WEN (KEVIN) | reporter.nih.gov |
| Elucidating the role of placental growth factor in diffuse white matter disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,517,370 | April 1, 2020 | July 15, 2023 | WILCOCK, DONNA M | reporter.nih.gov |
| Ion Channel Dysfunction in Small Vessel Disease of the Brain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,516,504 | April 15, 2019 | March 31, 2026 | NELSON, MARK T | reporter.nih.gov |
| Role of Monocyte Delta Like-4 (Dll4) in HIV-Associated Cerebral Small Vessel Disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,514,509 | August 1, 2024 | June 30, 2029 | SCHIFITTO, GIOVANNI | reporter.nih.gov |
| Intrinsic CSF outflow metrics for mild cognitive impairment and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,513,078 | May 15, 2024 | January 31, 2029 | MIYAZAKI, MITSUE | reporter.nih.gov |
| The impact of blood pressure variability on neurovascular function | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,512,730 | August 15, 2023 | May 31, 2028 | FILOSA, JESSICA A | reporter.nih.gov |
| Covert Cerebrovascular Disease Detected by Artificial Intelligence (C2D2AI): Pragmatic Neuroimaging Biomarkers for Future Stroke and Dementia Risk | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,504,012 | February 15, 2024 | January 31, 2028 | KENT, DAVID M | reporter.nih.gov |
| Using a Natural Experiment to Evaluate the Long-Term Effects of Neighborhood Deprivation on Alzheimer's Disease and Vascular Risk Factors | NIH | National Institute on Aging | 2021 to 2023 | $1,498,177 | May 1, 2019 | February 29, 2024 | HAMAD, RITA | reporter.nih.gov |
| Multi-Ethnic Study of Atherosclerosis- Cellular Exosomes in Neurodegeneration and Dementia (MESA-CEND) | NIH | National Institute on Aging | 2024 to 2025 | $1,486,033 | August 15, 2021 | July 31, 2026 | DEEP, GAGAN | reporter.nih.gov |
| Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosis | NIH | National Institute on Aging | 2024 to 2025 | $1,476,148 | April 1, 2021 | March 31, 2026 | VIDAL, RUBEN | reporter.nih.gov |
| Chemogenetic Neurovascular Oxidative Stress: Neurodegeneration and Cardiac Remodeling | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,475,301 | February 2, 2024 | January 31, 2029 | MICHEL, THOMAS | reporter.nih.gov |
| A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s Disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,466,564 | April 1, 2021 | March 31, 2026 | ZHAO, ZHEN | reporter.nih.gov |
| Age-related vascular cognitive impairment: role of endothelial senescence | NIH | National Institute on Aging | 2021 to 2024 | $1,450,000 | August 1, 2020 | July 31, 2025 | CSISZAR, ANNA | reporter.nih.gov |
| Central noradrenergic mechanisms of cerebrovascular pathology in Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2023 | $1,445,578 | April 1, 2019 | January 31, 2025 | COUNTS, SCOTT E | reporter.nih.gov |
| Non-Invasive MRI Markers to Elicit the Role of Vascular Disease in CADASIL Compared to Normal Aging | NIH | National Institute on Aging | 2024 to 2025 | $1,438,740 | February 15, 2024 | January 31, 2029 | EISENMENGER, LAURA BURNS | reporter.nih.gov |
| Exploring the origins of myelin abnormalities in normal ageing and in vascular dementia | NIH | National Institute on Aging | 2024 to 2025 | $1,434,950 | May 1, 2021 | April 30, 2026 | POPKO, BRIAN J | reporter.nih.gov |
| Cerebral Small Vessels in Motor and Cognitive Decline: Neuroimaging Signatures of Vulnerability & Resilience | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,434,665 | June 1, 2014 | March 31, 2027 | SOROND, FARZANEH A | reporter.nih.gov |
| Oligodendrocyte Precursor Cells Regulate White Matter Remodeling in Vascular Cognitive Impairment and Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,434,255 | July 1, 2019 | June 30, 2026 | ARAI, KEN | reporter.nih.gov |
| The protective role of microglia in preventing hypoxic disruption of blood-brain barrier integrity and VCID | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,423,377 | February 15, 2021 | January 31, 2027 | MILNER, D. RICHARD | reporter.nih.gov |
| 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s Disease | NIH | National Institute on Aging | 2024 to 2025 | $1,419,249 | September 1, 2024 | May 31, 2029 | WU, MINJIE | reporter.nih.gov |
| Hypoperfusion, Hemodynamic Control Domains and Neurovascular Dysregulation in AD brain pathology | NIH | National Institute on Aging | 2023 to 2025 | $1,414,971 | May 15, 2023 | January 31, 2027 | TURNER, DENNIS ALAN | reporter.nih.gov |
| Investigating the combined role of APOE4 and ketogenic diets in Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,410,026 | August 15, 2024 | April 30, 2029 | BLANCHARD, JOEL WILLIAM | reporter.nih.gov |
| Social Reward Processing Across the Lifespan: Identifying Risk Factors for Financial Exploitation | NIH | National Institute on Aging | 2024 to 2025 | $1,406,995 | April 15, 2021 | March 31, 2027 | SMITH, DAVID VICTOR | reporter.nih.gov |
| Pathways between OSA and cognitive decline in older women and men: a longitudinal population-based study | NIH | National Institute on Aging | 2021 to 2024 | $1,404,000 | August 15, 2021 | April 30, 2026 | BRALEY, TIFFANY JOY | reporter.nih.gov |
| The Role of Pericytes in the Vascular Dysfunction of Sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,381,815 | May 1, 2023 | March 31, 2028 | FAN, HONGKUAN | reporter.nih.gov |
| Non-invasive MRI mapping of BBB water exchange rate and permeability | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,380,588 | August 1, 2024 | May 31, 2029 | WANG, DANNY JJ | reporter.nih.gov |
| Cerebrovascular involvement in Alzheimer's Disease: PAR4 Antagonism | NIH | National Institute on Aging | 2024 to 2025 | $1,376,756 | May 15, 2021 | April 30, 2026 | HAMM, HEIDI E | reporter.nih.gov |
| Cortical Complications of Perimenopause and Obstructive Sleep Apnea in Underrepresented Middle-Aged Women with Type 2 Diabetes | NIH | National Institute on Aging | 2023 to 2024 | $1,358,585 | September 20, 2023 | August 31, 2025 | GORNIAK, STACEY LYNN | reporter.nih.gov |
| White Matter Injury and Repair in Vascular Cognitive Impairment and Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $1,357,361 | April 1, 2023 | March 31, 2026 | HU, XIAOMING | reporter.nih.gov |
| A QUANTITATIVE, PREDICTIVE MODEL OF VASCULAR REMODELING IN HEALTH AND DISEASE | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,356,041 | July 10, 2024 | May 31, 2028 | SCHWARTZ, MARTIN A | reporter.nih.gov |
| Astrocytic WNK-SPAK-NKCC1 Cascade in White Matter Astrogliosis and Injury | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $1,349,563 | April 15, 2022 | September 1, 2024 | BHUIYAN, MOHAMMAD IQBAL HOSSAIN | reporter.nih.gov |
| Examining a dose-dependent exercise intervention on cerebrovascular plasticity in late adulthood | NIH | National Institute on Aging | 2023 to 2025 | $1,348,549 | September 1, 2023 | May 31, 2027 | KIM, TAE | reporter.nih.gov |
| Chemogenetic Mouse Models for Cerebral Hypoperfusion and VCID | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,334,981 | July 1, 2024 | June 30, 2026 | SHIH, ANDY Y | reporter.nih.gov |
| Endothelial progenitor cells and neurovascular injury in the aging brain | NIH | National Institute on Aging | 2021 to 2023 | $1,321,673 | September 1, 2019 | August 1, 2023 | NATION, DANIEL A | reporter.nih.gov |
| Targeting Kruppel-like Transcription Factor for White and Grey Matter Protection in Vascular Cognitive Impairment and Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,316,276 | July 1, 2023 | April 30, 2029 | YIN, KEJIE | reporter.nih.gov |
| O-glycosylation of cysteine-rich modules | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,313,700 | January 1, 2023 | November 30, 2027 | HALTIWANGER, ROBERT S. | reporter.nih.gov |
| CRCNS: Waste-clearance flows in the brain measured using physics-informed neural network | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $1,284,101 | September 19, 2022 | June 30, 2027 | KELLEY, DOUGLAS H | reporter.nih.gov |
| Endothelial progenitor cells and neurovascular injury in the aging | NIH | National Institute on Aging | 2023 to 2025 | $1,282,491 | September 1, 2019 | June 30, 2030 | NATION, DANIEL A | reporter.nih.gov |
| Large-Scale Genomic Analysis of Aging-Related Cognitive Change Prior to Dementia Onset | NIH | National Institute on Aging | 2024 to 2025 | $1,278,361 | August 15, 2021 | July 31, 2027 | TUCKER-DROB, ELLIOT MAX | reporter.nih.gov |
| Long non-coding RNAs mediate white and grey matter integrity in vascular cognitive impairment and dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,267,624 | April 16, 2024 | March 31, 2029 | YIN, KEJIE | reporter.nih.gov |
| Pathogenic exosomes during herpes zoster mediate increased vascular dementia risk | NIH | National Institute on Aging | 2024 to 2025 | $1,264,545 | September 20, 2024 | July 31, 2029 | BUBAK, ANDREW N | reporter.nih.gov |
| Mapping the perivascular reticular network in health, aging, and AD | NIH | National Institute on Aging | 2023 | $1,246,362 | September 1, 2023 | August 31, 2026 | MEHTA, RUPAL I. | reporter.nih.gov |
| Single domain antibody development for improving vascular dysfunction in Alzheimer’s disease | NIH | National Institute on Aging | 2025 | $1,244,775 | September 20, 2025 | May 31, 2027 | HUSSAIN, SAZID | reporter.nih.gov |
| A Cerebrovascular Basis for Sex Differences in Alzheimer's Disease Risk | NIH | National Institute on Aging | 2021 to 2023 | $1,237,040 | April 15, 2020 | March 31, 2026 | WU, MINJIE | reporter.nih.gov |
| Neutrophil-driven vascular inflammation in VCID and Mixed Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,235,417 | September 17, 2024 | August 31, 2029 | BRACKO, OLIVER | reporter.nih.gov |
| The roles of pericyte-derived laminin in neurovascular function and neurodegeneration | NIH | National Institute on Aging | 2024 to 2025 | $1,221,061 | September 30, 2021 | August 31, 2026 | YAO, YAO | reporter.nih.gov |
| Using Photobiomodulation to Alleviate Brain Hypoperfusion in Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $1,190,898 | May 15, 2023 | January 31, 2028 | LIN, HUNG WEN (KEVIN) | reporter.nih.gov |
| Molecular Markers of Cerebrovascular Pathologies in Alzheimer's Disease and Related Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,188,426 | September 1, 2024 | August 31, 2028 | OBENAUS, ANDRE | reporter.nih.gov |
| Heparan sulfate proteoglycan in the brain vascular clearance of amyloid-β and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,187,855 | August 15, 2021 | July 31, 2027 | WANG, LIANCHUN | reporter.nih.gov |
| Cardiovascular and Cerebrovascular Risk Factors for Mobility Limitation in the Jackson Heart Study | NIH | National Institute on Aging | 2021 to 2023 | $1,169,210 | May 1, 2020 | February 28, 2026 | ODDEN, MICHELLE CHRISTINA | reporter.nih.gov |
| Imaging cerebral waste clearance responses during exosome treatment of diabetes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,164,662 | April 15, 2024 | March 31, 2029 | JIANG, QUAN | reporter.nih.gov |
| Adducin, actin cytoskeleton and cognitive impairments | NIH | National Institute on Aging | 2021 to 2023 | $1,162,500 | April 1, 2019 | January 31, 2025 | WILLIAMS, JAN MICHAEL | reporter.nih.gov |
| Cerebral microhemorrhages and gait abnormalities in aging | NIH | National Institute on Aging | 2021 to 2025 | $1,154,620 | September 15, 2024 | June 30, 2030 | CSISZAR, ANNA | reporter.nih.gov |
| Neurocognitive Impairment Assessment in Symptomatic Carotid Occlusion Recanalized Endovascularly: NIA SCORE | NIH | National Institute on Aging | 2022 to 2023 | $1,147,757 | April 15, 2020 | March 31, 2024 | HASAN, DAVID M. | reporter.nih.gov |
| StAtins Use in intRacereberal hemorrhage patieNts MRI (SATURN MRI) Ancillary Study | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,144,357 | August 15, 2021 | August 31, 2027 | SELIM, MAGDY H | reporter.nih.gov |
| Effect of diabetes and AD pathology on brain imaging and cognition in Latino adults | NIH | National Institute on Aging | 2025 | $1,134,850 | September 30, 2022 | August 31, 2027 | YASSINE, HUSSEIN N | reporter.nih.gov |
| Mechanistic inquiry of GPR68-mediated neuroprotection against post-stroke deficits and VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,131,657 | September 25, 2023 | August 31, 2029 | ZHA, XIANGMING | reporter.nih.gov |
| Interactions between the chronic sequelae of stroke and Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2023 | $1,130,696 | September 1, 2019 | May 31, 2025 | DOYLE, KRISTIAN PAUL | reporter.nih.gov |
| Vasculotide promotes cognitive improvement in rats with vascular dementia | NIH | National Institute on Aging | 2021 to 2023 | $1,128,750 | August 1, 2019 | April 30, 2025 | CHOPP, MICHAEL | reporter.nih.gov |
| Clinical Spectrum and Societal Impact of Cognitive Impairment with HIV in Uganda | NIH | National Institute on Aging | 2024 | $1,103,953 | September 15, 2024 | August 31, 2025 | SIEDNER, MARK J | reporter.nih.gov |
| Blood Pressure and ADRD in African Americans: the Jackson Heart Study | NIH | National Institute on Aging | 2023 | $1,102,700 | September 15, 2019 | May 31, 2026 | PALTA, PRIYA | reporter.nih.gov |
| The Contribution of Late Onset Unexplained Epilepsy to Cognitive Decline and its Interaction with Vascular and Alzheimer's Disease Pathologies | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,098,488 | September 1, 2021 | June 30, 2027 | SARKIS, RANI | reporter.nih.gov |
| Epigenetic Aging Biomarkers of Mild Cognitive Impairment, Alzheimer's Disease and Related Dementias, and Brain Aging | NIH | National Institute on Aging | 2024 to 2025 | $1,084,069 | August 1, 2021 | July 31, 2027 | SHADYAB, ALADDIN | reporter.nih.gov |
| Elucidating the role of placental growth factor in diffuse white matter disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $1,084,034 | June 1, 2023 | March 31, 2026 | WILCOCK, DONNA M | reporter.nih.gov |
| Novel regulation of vascular dementia | NIH | National Institute on Aging | 2024 to 2025 | $1,067,631 | August 1, 2023 | April 30, 2027 | CHEN, YABING | reporter.nih.gov |
| Contributions of educational quality and occupational complexity on racial and ethnic inequities in brain health and Alzheimer's disease and related dementia | NIH | National Institute on Aging | 2021 to 2023 | $1,059,807 | September 15, 2019 | May 31, 2025 | GILSANZ, PAOLA | reporter.nih.gov |
| Targeting RBC dysfunction in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,043,628 | July 15, 2021 | June 30, 2027 | HESS, DAVID C. | reporter.nih.gov |
| Elucidating microvascular contributions to cognitive impairment at single-cell resolution | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $1,042,742 | July 1, 2022 | December 31, 2023 | YANG, ANDREW CHRIS | reporter.nih.gov |
| Enhanced APOE2 Expression into Brain for Therapeutic Strategy for Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $1,040,909 | May 15, 2021 | April 30, 2027 | SINGH, JAGDISH | reporter.nih.gov |
| Single-cell multi-region transcriptional and epigenomic dissection of VCID. | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,034,087 | September 15, 2022 | August 31, 2027 | KELLIS, MANOLIS | reporter.nih.gov |
| Blood-brain-barrier and white matter mechanisms underlying dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,032,543 | February 1, 2021 | January 31, 2027 | LIAO, FRANCESCA-FANG | reporter.nih.gov |
| The role of PFAS in lipid-mediated vascular contributions to cognitive impairment and dementia: PFAS VascCog Longitudinal Study | NIH | National Institute on Aging | 2024 to 2025 | $1,032,220 | May 15, 2024 | January 31, 2029 | GARDENER, HANNAH | reporter.nih.gov |
| The Role of the Hippocampal Vasculature in Vascular Cognitive Impairment and Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,029,468 | April 1, 2022 | March 31, 2027 | CHAPMAN, ABBIE C | reporter.nih.gov |
| Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity (EXEC-study) | NIH | National Institute on Aging | 2022 to 2023 | $1,028,240 | May 1, 2022 | June 30, 2023 | BRONAS, ULF G | reporter.nih.gov |
| Targeting Receptor Interacting Protein Kinase-1 in the Chronic Period of Intracerebral Hemorrhage | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,018,126 | January 1, 2024 | December 31, 2028 | WHALEN, MICHAEL J | reporter.nih.gov |
| Validation of Novel Plasma Biomarkers for Mixed Etiology Dementia | NIH | National Institute on Aging | 2021 to 2025 | $1,005,750 | September 10, 2021 | May 31, 2026 | VANDEVREDE, LAWREN | reporter.nih.gov |
| Characterizing white matter injury in Alzheimer's disease | NIH | National Institute on Aging | 2025 | $1,001,700 | September 15, 2025 | August 31, 2029 | ROYSE, SARAH KOLIBASH | reporter.nih.gov |
| The effects of HIV-associated extracellular vesicles on mitochondrial dysfunction in brain microvessels | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $984,666 | July 10, 2024 | June 30, 2029 | CHANDRA, PARTHA | reporter.nih.gov |
| BBB Permeability Imaging in CADASIL | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $982,575 | February 1, 2020 | January 31, 2026 | WANG, DANNY JJ | reporter.nih.gov |
| Cerebrovascular resistance in cognitive aging and Alzheimer's disease risk | NIH | National Institute on Aging | 2021 to 2023 | $979,298 | August 1, 2019 | August 1, 2023 | NATION, DANIEL A | reporter.nih.gov |
| The Role of the Hippocampal Vasculature in Vascular Cognitive Impairment and Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $959,269 | April 1, 2022 | December 31, 2023 | CHAPMAN, ABBIE C | reporter.nih.gov |
| The mediating role of Slow Wave Sleep and Vascular Risk Factors on Alzheimer Disease related disparity between African-Americans and non-Hispanic Whites | NIH | National Institute on Aging | 2021 to 2025 | $957,738 | May 15, 2021 | April 30, 2026 | BUBU, OMONIGHO A MICHAEL | reporter.nih.gov |
| Stroke Disordered Breathing and its Impact on Cognitive Decline in Aging, Alzheimer's Disease and Cerebral Amyloid Angiopathy | NIH | National Institute on Aging | 2024 | $953,252 | September 11, 2020 | August 31, 2025 | LI, JUN | reporter.nih.gov |
| Cognitive Aging Brain Morphology and Arrhythmias in Hispanics/Latinos: Implications for Prevention and Management of Alzheimer's Disease-Related Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $947,878 | April 1, 2022 | March 31, 2027 | CHEN, LIN YEE | reporter.nih.gov |
| Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular contributions to Cognitive Impairment and Dementia (VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $942,355 | September 17, 2024 | August 31, 2029 | GARG, RAJEEV KUMAR | reporter.nih.gov |
| Simultaneous PET/MR Imaging of Brain Glucose and Oxygen Metabolism to Assess Energy Deficits Related to Alzheimer's Disease and the Response to Intervention | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $924,806 | March 26, 2024 | February 29, 2028 | WEHRLI, FELIX W | reporter.nih.gov |
| TRP channels as fundamental sensors of the cerebral microcirculation | NIH | National Heart, Lung, and Blood Institute | 2025 | $924,000 | February 1, 2021 | December 31, 2027 | EARLEY, SCOTT | reporter.nih.gov |
| Establishing Mechanisms Between Traumatic Brain Injury and Dementia Using Epidemiology, Clinical Studies, Blood-Based Biomarkers, and Neuroimaging Biomarkers | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $883,830 | May 1, 2022 | April 30, 2027 | SCHNEIDER, ANDREA LAUREN CHRISTMAN | reporter.nih.gov |
| Cerebromicrovascular rejuvenation by heterochronic blood exchange | NIH | National Institute on Aging | 2024 to 2025 | $875,461 | June 1, 2021 | May 31, 2027 | UNGVARI, ZOLTAN ISTVAN | reporter.nih.gov |
| Cognitive decline and dementia in older Kerala Americans | NIH | National Institute on Aging | 2024 | $855,415 | May 1, 2024 | February 28, 2029 | VERGHESE, JOE | reporter.nih.gov |
| Endothelial complement C3a receptor mediated cerebral injury in a murine stroke model. | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $853,135 | September 1, 2024 | August 31, 2029 | DUCRUET, ANDREW FREDERICK | reporter.nih.gov |
| The Impact of High Fat Diet on Brainstem Vagal Regulation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $837,791 | April 1, 2022 | March 31, 2027 | BOYCHUK, CARIE RENEE | reporter.nih.gov |
| Therapeutic effects of APOE regulation via LNP-RNA formulations in Alzheimer's disease | NIH | National Institute on Aging | 2025 | $835,417 | June 1, 2025 | March 31, 2030 | DONG, YIZHOU | reporter.nih.gov |
| Characterizing microvascular impairment in adults with elevated genetic risk for Alzheimer's Disease | NIH | National Institute on Aging | 2025 | $831,583 | March 15, 2025 | January 31, 2030 | JUTTUKONDA, MEHER R | reporter.nih.gov |
| PET imaging for in-vivo quantification of demyelination and cerebral perfusion in Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $829,125 | September 30, 2024 | May 31, 2029 | GUEHL, NICOLAS JEAN | reporter.nih.gov |
| Aerobic Exercise for Optimizing Cognitive and Brain Health In Remitted Late-Life Depression | NIH | National Institute of Mental Health | 2021 to 2025 | $828,059 | December 14, 2020 | November 30, 2026 | GUJRAL, SWATHI | reporter.nih.gov |
| Cognitive decline and dementia in older Kerala Americans | NIH | National Institute on Aging | 2025 | $820,874 | May 1, 2024 | February 28, 2029 | VERGHESE, JOE | reporter.nih.gov |
| Cognitive heterogeneity in those with high Alzheimer's Disease Risk | NIH | National Institute on Aging | 2025 | $817,404 | September 30, 2018 | November 30, 2028 | AU, RHODA | reporter.nih.gov |
| GPR4 in blood brain barrier dysfunction in brain ischemia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $815,761 | July 1, 2022 | August 1, 2024 | ZHA, XIANGMING | reporter.nih.gov |
| Identifying compounds that target APOE4 associated brain endothelial dysfunction | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $809,521 | February 3, 2022 | July 31, 2026 | TAI, LEON MAING | reporter.nih.gov |
| Marmosets as a Model for Understanding Social, Neuroendocrine, and Vascular Contributions to Cognitive Aging | NIH | National Institute on Aging | 2021 to 2023 | $804,994 | August 1, 2019 | April 30, 2025 | PHILLIPS, KIMBERLEY ANN | reporter.nih.gov |
| Dysfunction of brain microvascular and lymphatic vessels in obesity-linked cognitive impairment | NIH | National Institute on Aging | 2025 | $801,348 | June 1, 2025 | February 28, 2030 | SMITH, WANLI W | reporter.nih.gov |
| Targeting cerebrovascular Wnt/beta-catenin signaling to reverse brain endothelial damage induced by SARS-CoV-2 infection | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $801,329 | December 1, 2024 | November 30, 2029 | LUTZ, SARAH ELIZABETH | reporter.nih.gov |
| Vascular dysfunction in glaucoma | NIH | National Eye Institute | 2022 to 2023 | $797,500 | April 1, 2022 | March 31, 2027 | MUIR, ERIC RAYMOND | reporter.nih.gov |
| Blood-brain barrier and microstructural brain biomarkers of ARIA and treatment outcomes with anti-amyloid immunotherapy for Alzheimer's disease | NIH | National Institute on Aging | 2025 | $794,981 | January 1, 2025 | December 31, 2029 | REAS, EMILIE T. | reporter.nih.gov |
| Age-related Hypertension and Vascular Cognitive Impairment | NIH | National Institute on Aging | 2024 | $793,084 | February 1, 2022 | January 31, 2027 | WAINFORD, RICHARD DAVID | reporter.nih.gov |
| Computational Speech Analysis in Alzheimer's Disease and Other Neurocognitive Disorders | NIH | National Institute on Aging | 2021 to 2024 | $791,456 | May 1, 2020 | April 30, 2026 | PRESSMAN, PETER SCOTT | reporter.nih.gov |
| High-Speed Imaging of Cortical and White Matter Microvascular Flow in AD/ADRD Models | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $791,262 | August 15, 2022 | July 31, 2027 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Blood-brain barrier dysfunction in Alzheimer's disease: from humans to animal models | NIH | National Institute on Aging | 2024 | $788,363 | May 1, 2021 | April 30, 2027 | LU, HANZHANG | reporter.nih.gov |
| Systemic and dietary advanced glycation end products in type 2 diabetes-related cognitive decline and incident dementia: effects on Alzheimer's pathology and cerebrovascular disease | NIH | National Institute on Aging | 2024 | $787,175 | July 18, 2023 | November 30, 2025 | SCHNAIDER BEERI, MICHAL | reporter.nih.gov |
| Vascular Mechanisms of Dementia: Cell-Type Specific Therapeutic and Imaging Strategies | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $784,245 | July 1, 2022 | June 30, 2027 | GRUTZENDLER, JAIME | reporter.nih.gov |
| Brain cPLA2 as a mechanism for neuroinflammation in AD/ADRD with and without APOE4 | NIH | National Institute on Aging | 2025 | $780,961 | May 15, 2022 | April 30, 2027 | YASSINE, HUSSEIN N | reporter.nih.gov |
| B Cells Directly Alter Adaptive Plasticity to Support Functional Recovery After Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $779,321 | February 1, 2015 | June 30, 2027 | STOWE, ANN MARIE | reporter.nih.gov |
| Perivascular Inflammation and Vascular Remodeling: A Common Cause of Hemorrhage in Cerebral Small Vessel Diseases? | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $776,503 | August 1, 2023 | July 31, 2025 | VAN VELUW, SUSANNE JANNEKE | reporter.nih.gov |
| Quantitative cerebral blood vessel imaging biomarkers for AD and VCID | NIH | National Institute on Aging | 2025 | $775,949 | April 1, 2021 | March 31, 2027 | YAN, LIRONG | reporter.nih.gov |
| Endothelial protocadherins in vascular development and disease | NIH | National Heart, Lung, and Blood Institute | 2025 | $775,720 | August 15, 2025 | May 31, 2029 | SCHWARTZ, MARTIN A | reporter.nih.gov |
| Endothelial cell senescence and APOE4 in vascular cognitive impairment and dementia | NIH | National Institute on Aging | 2024 to 2025 | $774,675 | March 15, 2021 | February 28, 2026 | KANEKIYO, TAKAHISA | reporter.nih.gov |
| Role of Sox18 in neurovascular dysfunction in Alzheimer's disease | NIH | National Institute on Aging | 2025 | $772,581 | January 1, 2025 | November 30, 2029 | DANEMAN, RICHARD | reporter.nih.gov |
| Mechanistic and Functional Evaluation of a Model of Cerebral Small Vessel Disease | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $770,502 | May 1, 2025 | April 30, 2030 | GOULD, DOUGLAS | reporter.nih.gov |
| Lifespan Vascular Biology on White Matter | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $770,374 | August 15, 2020 | August 14, 2025 | MITCHELL, BRAXTON D | reporter.nih.gov |
| Repurposing of R-etodolac for Alzheimer's disease and related disorders | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $768,262 | September 1, 2023 | August 31, 2027 | KHALIL KADDOUMI, AMAL F | reporter.nih.gov |
| Mechanism of ARIA following Anti-Amyloid Immunotherapy | NIH | National Institute on Aging | 2025 | $766,133 | January 1, 2025 | November 30, 2029 | URAYAMA, AKIHIKO | reporter.nih.gov |
| STAT3 activation in astrocytes as a driver of neurovascular dysfunction in Alzheimer's disease and related dementias | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $765,645 | September 19, 2022 | August 31, 2027 | LIPPMANN, ETHAN | reporter.nih.gov |
| Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | NIH | National Institute on Aging | 2025 | $762,178 | May 15, 2022 | April 30, 2027 | SHIH, ANDY Y | reporter.nih.gov |
| Longitudinal transdisciplinary Neuropalliative care Support for Patients with Severe Stroke and their Families | NIH | National Institute on Aging | 2024 | $761,403 | August 15, 2024 | July 31, 2026 | CREUTZFELDT, CLAIRE JOHANNA | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Columbia University Health Sciences | New York, NY | 22 | $179.5 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 14 | $141.4 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 35 | $73 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 36 | $65.5 million | 0 | $0 |
| University of California at Davis | Davis, CA | 10 | $59 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 25 | $58.5 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 9 | $56.9 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 19 | $54.2 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 12 | $50.5 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 11 | $50.2 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 14 | $46.1 million | 0 | $0 |
| University of South Florida | Tampa, FL | 7 | $41.6 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 10 | $36.8 million | 0 | $0 |
| Tulane University of Louisiana | New Orleans, LA | 9 | $34.6 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 8 | $32.9 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 17 | $32.1 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 11 | $28.9 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 13 | $28.3 million | 0 | $0 |
| University of California-Berkeley | Berkeley, CA | 3 | $27.2 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 15 | $24.4 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 14 | $23.1 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 6 | $23 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 8 | $22.8 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 6 | $22.3 million | 0 | $0 |
| Duke University | Durham, NC | 11 | $22.2 million | 0 | $0 |
| University of Vermont & ST Agric College | Burlington, VT | 9 | $21.3 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 8 | $21.1 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 11 | $20.9 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 11 | $20.6 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 11 | $19.3 million | 0 | $0 |
| Emory University | Atlanta, GA | 7 | $18.9 million | 0 | $0 |
| Washington University | Saint Louis, MO | 8 | $18.5 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 7 | $17.9 million | 0 | $0 |
| Albert Einstein College of Medicine | Bronx, NY | 4 | $15.6 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 7 | $15.2 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 11 | $14.9 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 13 | $14.7 million | 0 | $0 |
| SUNY Downstate Medical Center | Brooklyn, NY | 1 | $14.1 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 6 | $14.1 million | 0 | $0 |
| Yale University | New Haven, CT | 13 | $13.6 million | 0 | $0 |
| University of New Mexico Health Scis CTR | Albuquerque, NM | 4 | $12.9 million | 0 | $0 |
| SUNY at Stony Brook | Stony Brook, NY | 6 | $12.7 million | 0 | $0 |
| Chapman University | Orange, CA | 1 | $12.7 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 7 | $11.8 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 10 | $11.7 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 3 | $11.5 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 9 | $11.2 million | 0 | $0 |
| Massachusetts Institute of Technology | Cambridge, MA | 6 | $10.4 million | 0 | $0 |
| University of Oklahoma HLTH Sciences CTR | Oklahoma City, OK | 10 | $9.8 million | 0 | $0 |
| University of Rochester | Rochester, NY | 7 | $9.7 million | 0 | $0 |
| Board of Regents, NSHE, obo University of Nevada, Reno | Reno, NV | 4 | $9.6 million | 0 | $0 |
| Regenerative Research Foundation | Albany, NY | 2 | $8.9 million | 0 | $0 |
| Stanford University | Stanford, CA | 9 | $8.8 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 8 | $8.6 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 5 | $8.4 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 9 | $8.4 million | 0 | $0 |
| Jackson Laboratory | Bar Harbor, ME | 4 | $8.1 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 2 | $8 million | 0 | $0 |
| Pennsylvania State Univ University Park | University Park, PA | 1 | $7.9 million | 0 | $0 |
| J. David Gladstone Institutes | San Francisco, CA | 2 | $7.7 million | 0 | $0 |
| Medical University of South Carolina | Charleston, SC | 4 | $7.2 million | 0 | $0 |
| Augusta University | Augusta, GA | 6 | $6.9 million | 0 | $0 |
| University of Washington | Seattle, WA | 4 | $6.6 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 5 | $6.5 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 2 | $6.3 million | 0 | $0 |
| LSU Pennington Biomedical Research CTR | Baton Rouge, LA | 2 | $6.2 million | 0 | $0 |
| University of Florida | Gainesville, FL | 6 | $6.1 million | 0 | $0 |
| Washington State University | Pullman, WA | 2 | $6.1 million | 0 | $0 |
| Cornell University | Ithaca, NY | 3 | $5.7 million | 0 | $0 |
| Hugo W. Moser Res Inst Kennedy Krieger | Baltimore, MD | 3 | $5.6 million | 0 | $0 |
| University of TX MD Anderson Can CTR | Houston, TX | 2 | $5.4 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 4 | $5.1 million | 0 | $0 |
| Seattle Children's Hospital | Seattle, WA | 4 | $4.9 million | 0 | $0 |
| Henry Ford Health + Michigan State University Health Sciences | East Lansing, MI | 3 | $4.7 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 3 | $4.6 million | 0 | $0 |
| Tufts Medical Center | Boston, MA | 2 | $4.6 million | 0 | $0 |
| University of Edinburgh | Edinburgh | 2 | $4.5 million | 0 | $0 |
| University of New South Wales | Sydney | 1 | $4.4 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 3 | $4.3 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 4 | $4.3 million | 0 | $0 |
| Ohio State University | Columbus, OH | 4 | $4.2 million | 0 | $0 |
| Magee-Women's Res Inst and Foundation | Pittsburgh, PA | 1 | $4 million | 0 | $0 |
| Aromha, Inc. | Potomac, MD | 1 | $3.7 million | 0 | $0 |
| Pennsylvania State Univ Hershey Med CTR | Hershey, PA | 2 | $3.7 million | 0 | $0 |
| University of Connecticut SCH of Med/dnt | Farmington, CT | 3 | $3.7 million | 0 | $0 |
| Rockefeller University | New York, NY | 1 | $3.4 million | 0 | $0 |
| Trustees of Boston University | Boston, MA | 2 | $3.3 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 1 | $3.1 million | 0 | $0 |
| Therini Bio, Inc. | Sacramento, CA | 1 | $3 million | 0 | $0 |
| Evon Medics, LLC | Elkridge, MD | 1 | $2.9 million | 0 | $0 |
| Gen-9, Inc. | Mountain View, CA | 1 | $2.9 million | 0 | $0 |
| West Virginia University Research Corporation | Morgantown, WV | 3 | $2.8 million | 0 | $0 |
| Albany Medical College | Albany, NY | 1 | $2.7 million | 0 | $0 |
| Loma Linda University | Loma Linda, CA | 1 | $2.7 million | 0 | $0 |
| North Dakota State University Fargo | Fargo, ND | 2 | $2.6 million | 0 | $0 |
| Florida International University | Miami, FL | 1 | $2.6 million | 0 | $0 |
| Rhode Island Hospital | Providence, RI | 1 | $2.6 million | 0 | $0 |
| Together Senior Health, Inc. | New York, NY | 1 | $2.5 million | 0 | $0 |
| Neuroscope Inc. | Scarsdale, NY | 1 | $2.4 million | 0 | $0 |
| ST. Joseph's Hospital and Medical Center | Phoenix, AZ | 2 | $2.4 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 479 | $456,863,620 | 0 | $0 |
| 2024 | 494 | $497,599,238 | 0 | $0 |
| 2023 | 468 | $480,414,582 | 0 | $0 |
| 2022 | 289 | $288,343,710 | 0 | $0 |
| 2021 | 193 | $225,247,220 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 4, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-04). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.