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Data / Research funding / Traumatic Head and Spine Injury

Traumatic Head and Spine Injury: 1,149 NIH awards ($1.5B) to 263 organizations

1,149 NIH awards ($1.5B) in the NIH spending category Traumatic Head and Spine Injury, to 263 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 1,149 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$15,805,224July 1, 2018November 30, 2025BARSAN, WILLIAM Greporter.nih.gov
1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAHNIHNational Institute on Drug Abuse2021 to 2025$13,649,176September 30, 2015March 31, 2027YURGELUN-TODD, DEBORAH A.reporter.nih.gov
Endophenotypes of Persistent Post-Concussive Symptoms in Adolescents: CARE4KidsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$12,522,070September 8, 2021March 31, 2027GIZA, CHRISTOPHER Creporter.nih.gov
5/21 ABCD-USA Consortium: Research Project Site at UC San DiegoNIHNational Institute on Drug Abuse2021 to 2025$10,821,558September 30, 2015March 31, 2027TAPERT, SUSAN F.reporter.nih.gov
9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGANNIHNational Institute on Drug Abuse2021 to 2025$10,318,458September 30, 2015March 31, 2027HEITZEG, MARY Mreporter.nih.gov
15/21 ABCD-USA Consortium: Research Project Site at LIBRNIHNational Institute on Drug Abuse2021 to 2025$10,302,955April 15, 2020March 31, 2027PAULUS, MARTIN P.reporter.nih.gov
4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIUNIHNational Institute on Drug Abuse2021 to 2025$9,979,334September 30, 2015March 31, 2027GONZALEZ, RAULreporter.nih.gov
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLNIHNational Institute on Drug Abuse2021 to 2025$9,776,479April 15, 2020March 31, 2027MADDEN, PAMELA ANNreporter.nih.gov
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a TrialNIHNational Institute on Aging2021 to 2025$9,481,336February 15, 2021November 30, 2026HANLEY, DANIEL Freporter.nih.gov
2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMBNIHNational Institute on Drug Abuse2021 to 2025$9,449,174September 30, 2015March 31, 2027ERNST, THOMAS Mreporter.nih.gov
University of New Mexico (UNM) Center for Brain Recovery and RepairNIHNational Institute of General Medical Sciences2021 to 2024$9,061,444September 15, 2015June 30, 2026SHUTTLEWORTH, CLAUDE Wreporter.nih.gov
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,833,081April 15, 2022March 31, 2027GALANOPOULOU, ARISTEA Sreporter.nih.gov
7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALENIHNational Institute on Drug Abuse2021 to 2025$8,739,227September 30, 2015March 31, 2027BASKIN-SOMMERS, ARIELLE RYANreporter.nih.gov
19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVMNIHNational Institute on Drug Abuse2021 to 2025$8,669,646April 15, 2020March 31, 2027GARAVAN, HUGH P.reporter.nih.gov
3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTANIHNational Institute on Drug Abuse2021 to 2025$8,298,588September 30, 2015March 31, 2027LUCIANA, MONICAreporter.nih.gov
6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSUNIHNational Institute on Drug Abuse2021 to 2025$8,270,799September 30, 2015March 31, 2027NAGEL, BONNIE J.reporter.nih.gov
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderNIHNational Institute on Drug Abuse2021 to 2025$8,148,103April 15, 2020March 31, 2027BANICH, MARIE Treporter.nih.gov
20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCUNIHNational Institute on Drug Abuse2021 to 2025$7,897,207April 15, 2020March 31, 2027BJORK, JAMES Mreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,746,716September 15, 2021August 31, 2028BOGNER, JENNIFER Areporter.nih.gov
University of Maryland Claude D. Pepper Older Americans Independence Center (OAIC)NIHNational Institute on Aging2021 to 2025$6,970,364September 15, 2006June 30, 2027RYAN, ALICE S.reporter.nih.gov
18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDANIHNational Institute on Drug Abuse2021 to 2025$6,741,640April 15, 2020March 31, 2027NIXON, SARA JOreporter.nih.gov
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGHNIHNational Institute on Drug Abuse2021 to 2025$6,727,386September 30, 2015March 31, 2027CLARK, DUNCAN B.reporter.nih.gov
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRINIHNational Institute on Drug Abuse2021 to 2025$6,613,511September 30, 2015March 31, 2027BAKER, FIONA Creporter.nih.gov
17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLANIHNational Institute on Drug Abuse2021 to 2025$6,450,915April 15, 2020March 31, 2027DAPRETTO, MIRELLAreporter.nih.gov
Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project IINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$6,308,426August 15, 2024July 31, 2029ALOSCO, MICHAELreporter.nih.gov
Traumatic Brain Injury and Repetitive Head Impacts: Contributions to AD/ADRD and CTE Neuropathology and Resulting Clinical SyndromesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,142,337September 30, 2019July 31, 2025MCKEE, ANN C.reporter.nih.gov
Spinal circuits for mechanical itch and light touchNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,110,688May 1, 2019April 30, 2027GOULDING, MARTYN Dreporter.nih.gov
Restoration of Grasp and Reach in Cervical Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,968,318March 1, 2018August 31, 2025KILGORE, KEVIN L.reporter.nih.gov
11/21 ABCD-USA Consortium: Research Project Site at UWMNIHNational Institute on Drug Abuse2021 to 2025$5,941,105July 15, 2017March 31, 2027LISDAHL, KRISTA MAURINEreporter.nih.gov
URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related DementiasNIHNational Institute on Aging2021 to 2024$5,941,036September 1, 2019May 31, 2026NELSON, LONNIE A.reporter.nih.gov
13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSCNIHNational Institute on Drug Abuse2021 to 2025$5,745,020July 1, 2017March 31, 2027SQUEGLIA, LINDSAYreporter.nih.gov
Intracranial multimodal physiological monitoring in acute brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,648,369August 15, 2022July 31, 2025SPENCER, DENNIS Dreporter.nih.gov
Overcoming Neurogenic “Meta-Inflammation” to Promote Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,600,627May 1, 2019April 30, 2027POPOVICH, PHILLIP Greporter.nih.gov
16/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UNIVERSITY OF ROCHESTERNIHNational Institute on Drug Abuse2021 to 2025$5,419,981April 15, 2020March 31, 2027FOXE, JOHN Jreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$5,043,999September 15, 2021August 31, 2023BOGNER, JENNIFER Areporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2022$5,005,696September 1, 2022August 31, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Spinal Cord Stimulation to Improve Motor Function in People with Post-Stroke HemiplegiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$4,671,700September 8, 2022August 31, 2025CAPOGROSSO, MARCOreporter.nih.gov
Hyperbaric Oxygen Brain Injury Treatment (HOBIT) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,664,374September 30, 2017June 30, 2029ROCKSWOLD, GAYLAN Lreporter.nih.gov
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid AnalgesicsNIHNational Institute on Drug Abuse2024 to 2025$4,623,799September 30, 2019December 31, 2026CORTES-PUCH, IRENEreporter.nih.gov
Brain fluid clearance and misfolded protein dynamics following traumatic brain injuryNIHNational Institute on Aging2023 to 2025$4,618,282September 30, 2023June 30, 2029BUTLER, TRACY A.reporter.nih.gov
Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk FactorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,613,790December 15, 2015November 30, 2023STERN, ROBERT Areporter.nih.gov
Sensory Motor Transformations in Human CortexNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,572,652August 15, 2021July 31, 2026ANDERSEN, RICHARD Areporter.nih.gov
An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCIDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,539,313September 22, 2023August 31, 2028VAN DER KOUWE, ANDRE JAN WILLEMreporter.nih.gov
Optimizing ultraflexible electrodes and integrated electronics for high-resolution, large-scale intraspinal recording and modulationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,423,695August 15, 2023July 31, 2027XIE, CHONGreporter.nih.gov
Tools for Common Data Element Adoption in the Pan-Neurotrauma Data Commons (PANORAUMA)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,311,013September 1, 2021January 31, 2026FERGUSON, ADAM Rreporter.nih.gov
The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)NIHNational Institute of Neurological Disorders and Stroke2021$4,283,451May 8, 2020November 30, 2022TOGA, ARTHUR Wreporter.nih.gov
Consequences of Exposure to Repetitive Head Impacts Across the LifespanNIHNational Institute of Neurological Disorders and Stroke2025$4,269,339June 1, 2025May 31, 2027MCKEE, ANN C.reporter.nih.gov
Neuroimaging and clinical Endpoints With High-dimensional analysis Of Pathological Endophenotypes in TBI (NEW-HOPE-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$4,213,033August 15, 2024July 31, 2029KEENE, CHRISTOPHER DIRKreporter.nih.gov
Genome-Wide Discovery and Translational Research for Neural RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,147,990December 1, 2016November 30, 2025STRITTMATTER, STEPHEN Mreporter.nih.gov
A Biomimetic Approach Towards a Dexterous NeuroprosthesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$4,074,988September 30, 2018June 30, 2025BONINGER, MICHAEL L.reporter.nih.gov
Transdisciplinary Research Accelerating Neuropathology Studies and Facilitating Open Research Methods in TBI (TRANSFORM-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,951,871June 1, 2024April 30, 2029SMITH, DOUGLAS HAMILTONreporter.nih.gov
Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,917,121February 1, 2021January 31, 2027ALOSCO, MICHAELreporter.nih.gov
Characterizing Wnt Signaling Pathways in Axon GuidanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,896,283June 15, 2023May 31, 2026ZOU, YIMINreporter.nih.gov
Multicellular Mechanisms Driving Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,884,176May 17, 2021April 30, 2029CAVALLI, VALERIAreporter.nih.gov
Minimally Invasive Cerebral Blood Flow and Oxygenation Monitoring for Intracranial HypertensionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,861,972September 20, 2022November 30, 2026FLOYD, THOMAS FREDERICKreporter.nih.gov
Defining the Role of Post-TBI Sleep Disruption in the Development of CTE and Alzheimer's Disease-Related NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2022$3,859,922September 20, 2022August 31, 2025PESKIND, ELAINE R.reporter.nih.gov
Language Processing in Context Following Traumatic Brain InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,792,881December 11, 2019May 31, 2030DUFF, MELISSA Creporter.nih.gov
Epidural spinal cord stimulation and respiratory motor function after injuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,733,906May 1, 2021February 28, 2027OVECHKIN, ALEXANDER VLADIMIROVICHreporter.nih.gov
Stimulation of novel spinal respiratory circuit to restore breathing in ventilator-dependent patients with SCI.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,702,825August 1, 2021December 31, 2027LU, DANIELreporter.nih.gov
Targeting Cell-Type Specific Disease Phenotypes to Promote CNS RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,654,519August 1, 2023April 30, 2028LEE, JAE Kreporter.nih.gov
Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)NIHNational Institute on Aging2021 to 2023$3,567,627March 15, 2019November 30, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Development and validation of a porcine model of spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$3,560,956September 21, 2023August 31, 2026FLOYD, CANDACE L.reporter.nih.gov
Locomotor function following transcutaneous electrical spinal cord stimulation in individuals with hemiplegic strokeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,493,081August 12, 2021July 31, 2027JAYARAMAN, ARUNreporter.nih.gov
Visuomotor Prosthetic for ParalysisNIHNational Eye Institute2021 to 2025$3,468,480May 1, 2021March 31, 2026ANDERSEN, RICHARD Areporter.nih.gov
Enhancing Respiratory Motor Function after Spinal Cord InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,467,620January 1, 2019March 31, 2027SIECK, GARY C.reporter.nih.gov
SMART Stepped Care Management for Low Back Pain in Military Health SystemNIHNational Center for Complementary & Integrative Health2021 to 2022$3,420,219September 20, 2017August 31, 2025FRITZ, JULIE Mreporter.nih.gov
Blood-based AD biomarkers profile in CAPCOG-TBI studyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,393,269September 1, 2023May 31, 2028DING, KANreporter.nih.gov
Brain Injury Outpatient Education and Care NavigationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,389,312August 15, 2021April 30, 2027RIVARA, FREDERICK P.reporter.nih.gov
Defining short RNA therapeutics that combat TDP-43 proteinopathy connected to AD and ADRDs.NIHNational Institute on Aging2025$3,360,074September 15, 2025August 31, 2029SHORTER, JAMESreporter.nih.gov
The Primate Corticospinal Connectome and TranscriptomeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,321,910September 15, 2017May 31, 2026TUSZYNSKI, MARK H.reporter.nih.gov
Contributions of astrocyte RelA signaling in aging-related neurodegenerative sequelae following TBINIHNational Institute on Aging2021 to 2025$3,313,377January 15, 2021December 31, 2026MORGANTI, JOSHreporter.nih.gov
Spinal Cord Associative PlasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,299,466September 10, 2021June 30, 2026CARMEL, JASON BRANTreporter.nih.gov
A longitudinal study of traumatic brain injury in a high-risk populationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,150,729August 4, 2022May 31, 2027KIEHL, KENT Areporter.nih.gov
Multiscale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor controlNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,147,181September 16, 2016March 31, 2027TING, LENA Hreporter.nih.gov
Longitudinal MRI Investigation of Traumatic Microvascular InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,116,729February 15, 2022January 31, 2027WARE, JEFFREY Breporter.nih.gov
Modeling the role of age at traumatic brain injury in the development of Alzheimer's Disease and related dementiasNIHNational Institute of Neurological Disorders and Stroke2024$3,109,079August 1, 2024July 31, 2027OBENAUS, ANDREreporter.nih.gov
Exosome biology in Alzheimer's disease and concussionNIHNational Institute on Aging2021 to 2025$3,108,983August 15, 2021April 30, 2027GRANHOLM-BENTLEY, ANN-CHARLOTTE ESTHERreporter.nih.gov
Developing Gyrencephalic Models of TBI-Induced ADRD NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2024$3,102,638August 15, 2024July 31, 2027JOHNSON, VICTORIA ELEANORreporter.nih.gov
Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,082,121March 15, 2020February 28, 2027DIAZ-ARRASTIA, RAMONreporter.nih.gov
Spinal Reflex Conditioning System for Enhancing Motor Function Recovery After Incomplete Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,077,317September 30, 2020December 31, 2026CLEMENTS, ISAAC PERRYreporter.nih.gov
The glymphatic system at the crossroad of integrative health approaches inchronic painNIHNational Center for Complementary & Integrative Health2021 to 2025$3,067,927August 1, 2021May 31, 2026NEDERGAARD, MAIKENreporter.nih.gov
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathiesNIHNational Institute on Aging2022 to 2025$3,053,656June 1, 2022February 28, 2027LIAO, DEZHIreporter.nih.gov
Maladaptive Plasticity in Spinal Cord Injury: Cellular MechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,505July 15, 2021June 30, 2026FERGUSON, ADAM Rreporter.nih.gov
Macrophage Depletion Therapy for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,324March 15, 2021November 30, 2025GENSEL, JOHN Creporter.nih.gov
Characterization of spinal circuits underlying motor synergy functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,029,088September 1, 2021August 31, 2026PFAFF, SAMUEL L.reporter.nih.gov
Strategy to Potentiate Rehabilitation after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,022,533December 1, 2020November 30, 2026HARRIS, NEILreporter.nih.gov
Pediatric Severe Traumatic Brain Injury in Latin America – A Randomized Trial Comparing Two Management ProtocolsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,020,262August 1, 2021July 31, 2027CHESNUT, RANDALL Mreporter.nih.gov
Development of a Novel Chemokine Receptor Antagonist Peptide as a Non-Opioid Treatment for Relief of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021$2,999,505September 15, 2021August 31, 2023RUFF, MICHAEL Rreporter.nih.gov
Development of a novel, regenerative therapy to reverse synapse loss in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$2,994,510June 1, 2023May 31, 2025VANDERKLISH, PETER Wreporter.nih.gov
Analytical characterization and validation of blood-biomarkers for monitoring TBI evolutionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,965,270August 10, 2024July 31, 2028PUCCIO, AVA M.reporter.nih.gov
Comprehensive Outcome Assessment after Severe Acute Brain Injury: Advanced Symptoms and End-of-Life Care NeedsNIHNational Institute of Nursing Research2021 to 2025$2,965,004May 12, 2021March 31, 2027CREUTZFELDT, CLAIRE JOHANNAreporter.nih.gov
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,919,684April 1, 2021March 31, 2026CULLEN, DANIEL KACYreporter.nih.gov
Preclinical Toxicology Study of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,885,957April 1, 2022August 31, 2027SUN, MIAOreporter.nih.gov
Functional Mechanism of Neural Control in Post-Concussion Convergence InsufficiencyNIHNational Eye Institute2021 to 2025$2,883,808April 1, 2014August 31, 2026ALVAREZ, TARA LYNNreporter.nih.gov
A youth-specific helmet for preventing traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023$2,864,855September 30, 2020August 31, 2025AVERY, GORDONreporter.nih.gov
Poly-omic predictors of symptom duration and recovery for adolescent concussionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,846,441January 1, 2020December 31, 2026HICKS, STEVEN DANIELreporter.nih.gov
From Neural Control of Movement to Treatments for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,832,066May 17, 2021April 30, 2029PEREZ, MONICA Areporter.nih.gov
A Translational Evaluation of Sur1-Trpm4 Imaging Endophenotypes and Genetics to Direct Precision Medicine for Cerebral Edema After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,799,271May 5, 2021April 30, 2027JHA, RUCHIRA MENKAreporter.nih.gov
The Importance of Abnormal Inflammasome Activation as a Risk Factor between Traumatic Brain Injury and Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,797,800September 20, 2021August 31, 2026DIETRICH, W DALTONreporter.nih.gov
Subconcussive neurodegenerative progression in adolescent athletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,789,923December 15, 2020November 30, 2026KAWATA, KEISUKEreporter.nih.gov
Recovery among Older Adults Following Head InjuryNIHNational Institute on Aging2022 to 2025$2,752,989July 1, 2022March 31, 2027ALBRECHT, JENNIFER S.reporter.nih.gov
Resting State Connectivity in Primate Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,739,668February 15, 2016July 31, 2026GORE, JOHN Creporter.nih.gov
Mitigating neuroinflammation and enhancing neuronal integrity in Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$2,738,640September 30, 2022June 30, 2027MA, JIANJIEreporter.nih.gov
3D Models of the Blood-Brain Barrier for Studying Trauma-Induced Cerebral and Systemic InjuriesNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,735,039September 3, 2020August 31, 2025ZHENG, YINGreporter.nih.gov
Paired Brain and Spinal Cord Stimulation to Strengthen Spinal Sensorimotor CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,692,011December 15, 2020November 30, 2025CARMEL, JASON BRANTreporter.nih.gov
Modulating Exercise Dosage to Improve Concussion Rehabilitation: A Randomized Clinical TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,688,941May 15, 2022March 31, 2027HOWELL, DAVID R.reporter.nih.gov
SV2A PET in Spinal Cord Injury ImagingNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,688,423July 1, 2022June 30, 2027CAI, ZHENGXINreporter.nih.gov
Structural characterization of tau conformational heterogeneity in Down syndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,686,309August 1, 2025July 31, 2026SOUTHWORTH, DANIEL RYLANDreporter.nih.gov
Spinal cord injury causes liver pathology and metabolic dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,668,295April 1, 2021March 31, 2027MCTIGUE, DANA Mreporter.nih.gov
Amyloid-mediated cognitive dysfunction in bacterial pneumonia after TBINIHNational Institute on Aging2025$2,663,195September 15, 2025August 31, 2029WAGENER, BRANT Mreporter.nih.gov
Rehabilitation from Spinal Cord Injury Using Targeted, Activity-Dependent Intraspinal StimulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,662,265August 15, 2021July 31, 2026PERLMUTTER, STEVE Ireporter.nih.gov
identifying Concussed Adolescents at Risk for Emotional dysregulation 2 (iCARE2)NIHNational Institute of Mental Health2021 to 2025$2,660,976December 19, 2017May 31, 2029VERSACE, AMELIAreporter.nih.gov
Enhancing the function of hippocampal neurons after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,654,614June 1, 2021March 31, 2027DASH, PRAMOD Kreporter.nih.gov
High Sensitivity Diffuse Optical Tomography of Human Brain FuncitonNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,642,789August 1, 2009November 30, 2026CULVER, JOSEPH Preporter.nih.gov
Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization InitiativeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,639,985September 30, 2020May 31, 2027HILLARY, FRANK GERARDreporter.nih.gov
Augmenting Implanted Neuroprosthetics with Targeted Health Monitoring for Spinal Cord Injury - the LIFELINENIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,632,178July 1, 2021March 31, 2026KILGORE, KEVIN L.reporter.nih.gov
Divergent age-dependent peripheral innate immune response following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,619,872July 1, 2021June 30, 2027THEUS, MICHELLE LEEreporter.nih.gov
Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal HydrocephalusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,613,622September 30, 2020April 30, 2030HWANG, MISUNreporter.nih.gov
Mitochondrial Uncoupling Prodrug as a Translational Therapy for TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,607,985March 15, 2020July 31, 2026SULLIVAN, PATRICK Greporter.nih.gov
Neurovascular unit dysfunction in Down syndrome revealed by TBINIHNational Institute of Neurological Disorders and Stroke2022$2,601,812September 7, 2022August 31, 2025HUANG, MINGXIAreporter.nih.gov
Prefrontal Anatomic Pathways in Executive ControlNIHNational Institute of Mental Health2021 to 2024$2,592,328July 1, 1987January 31, 2026BARBAS, HELENreporter.nih.gov
Development of a novel peptide therapeutic for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,571,585February 3, 2025March 31, 2026MANN, AMANreporter.nih.gov
Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,544,711March 15, 2020February 28, 2025DUFF, MELISSA Creporter.nih.gov
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,544,362December 1, 2021August 31, 2027SAYENKO, DIMITRYreporter.nih.gov
Multi-Center Clinical Trial of Spinal Cord Stimulation to Restore CoughNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,537,531September 22, 2022August 31, 2025DIMARCO, ANTHONY F.reporter.nih.gov
Diffusion MRI Model Parameter Estimation to Study Brain Microstructure as it Relates to Cognitive Status in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,534,685August 15, 2021July 31, 2025LUI, YVONNE Wreporter.nih.gov
Sustained Delivery of Tizanidine for Maintenance Treatment of Moderate to Severe SpasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,527,179April 15, 2019August 31, 2025WATKINS, GREGORYreporter.nih.gov
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,525,196August 1, 2020July 31, 2026GILMORE, EMILYreporter.nih.gov
Neuronal and behavioral responses to spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,519,438March 1, 2015February 28, 2026DARIAN-SMITH, CORINNAreporter.nih.gov
Personalized Profiles of Pathology in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,515,544January 1, 2022November 30, 2026DENNIS, EMILY LARSENreporter.nih.gov
The Contribution of Repetitive Head Impacts and Social Determinants of Health to Alzheimer's Disease and Related Dementia in Older Adult Black MenNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,514,590August 15, 2023July 31, 2028TURNER, ROBERT W.reporter.nih.gov
The inflammatory mechanisms underlying olfactory dysfunction in prognosis of TBI progression to dementiaNIHNational Institute on Aging2022 to 2025$2,508,327June 15, 2022March 31, 2027WU, JUNFANGreporter.nih.gov
Longitudinal Assessment of Driving After Mild TBI in TeensNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,507,174September 11, 2020July 31, 2026YANG, JINGZHEN GINGERreporter.nih.gov
Traumatic Brain Injury Anti-Seizure Prophylaxis in the Medicare ProgramNIHNational Institute on Aging2023 to 2025$2,504,051September 15, 2023May 31, 2028MOURA, LIDIA MARIA VERAS ROCHA DEreporter.nih.gov
Robust and Rapid 3D High-Resolution Cranial bone imaging for pediatric patients using MRINIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,488,491December 1, 2021November 30, 2026AN, HONGYUreporter.nih.gov
Exploiting sex-dependent brain injury response for nanoparticle therapeuticsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,482,558January 1, 2021November 30, 2025STABENFELDT, SARAH Ereporter.nih.gov
Mobile Subthreshold Exercise Program for Concussion (M-STEP)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,482,057September 8, 2020August 31, 2025CHRISMAN, SARA P.D.reporter.nih.gov
Customizable cooperative multi-joint control to enhance walking mobility after strokeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,481,207September 15, 2022June 30, 2027MAKOWSKI, NATHANIEL STEVENreporter.nih.gov
Genetic dissection of trait variation between long-diverged mouse speciesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,481,029September 30, 2019June 30, 2025BREM, RACHEL BETHreporter.nih.gov
Bidirectional Brain-Gut interactions, chronic neuroinflammation and neurodegeneration after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,480,051August 15, 2022July 31, 2027FADEN, ALAN IRAreporter.nih.gov
Multimodality Intervention to Improve Function and Metabolism in Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,474,995August 21, 2018April 30, 2024BHASIN, SHALENDERreporter.nih.gov
Novel mechanisms suppressing the pro-resolving phenotype of peripheral innate immunity following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,473,913June 1, 2021March 31, 2027THEUS, MICHELLE LEEreporter.nih.gov
The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,466,010April 1, 2024August 31, 2026SCHWULST, STEVEN Jreporter.nih.gov
Brain lymphatic activation for craniosynostosis and Alzheimer’s diseaseNIHNational Institute of Neurological Disorders and Stroke2024$2,461,369June 1, 2024May 31, 2027CHEN, JIANFUreporter.nih.gov
Dysregulation of autophagy-lysosomal function links TBI to late-onset neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,458,515April 1, 2020March 31, 2026LIPINSKI, MARTA Mreporter.nih.gov
Respiratory interneuron circuit plasticity: promoting recovery of diaphragm function after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,455,409March 1, 2013April 30, 2028LEPORE, ANGELO C.reporter.nih.gov
mHealth-based Just-In-Time Adaptive Intervention to Improve Physical Activity Levels of Individuals with Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,452,410July 20, 2021December 31, 2026HIREMATH, SHIVAYOGI Vreporter.nih.gov
EValuation Of Longitudinal outcomes in mild TBI Active-Duty Military and VEterans 10-YearNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,448,807April 1, 2015April 30, 2026MACDONALD, CHRISTINE Lreporter.nih.gov
Trauma, the gut, and the brain: the gut microbiota-microglia axis in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,439,002August 1, 2022July 31, 2027SCHWULST, STEVEN Jreporter.nih.gov
von Willebrand Factor in Traumatic Brain Injury and Associated CoagulopathyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,120April 1, 2020March 31, 2025DONG, JING-FEIreporter.nih.gov
The Contribution of Age-Related Tauopathies to Alzheimer's DiseaseNIHNational Institute on Aging2023$2,430,703September 30, 2018August 31, 2026MCKEE, ANN C.reporter.nih.gov
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,423,278January 15, 2021November 30, 2026ESOPENKO, CARRIE LYNNreporter.nih.gov
Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,420,406August 15, 2020July 31, 2025GRAHN, PETER JONASreporter.nih.gov
Novel tools for in vitro electrophysiology and neurotrauma modelingNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,414,021August 17, 2020January 31, 2026FINAN, JOHN Dreporter.nih.gov
A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury (SCI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,395,166September 15, 2020April 30, 2027LAD, SHIVANAND Preporter.nih.gov
OpenSim Enhancements to Enable Computational Design of Personalized Treatments for Movement ImpairmentsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,391,188September 6, 2021May 31, 2026FREGLY, BENJAMIN Jreporter.nih.gov
Propriopsinal neuron function in normal and post-SCI locomotionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,389,077March 15, 2021January 31, 2027MAGNUSON, DAVID SKreporter.nih.gov
Building and implementing a TBI prognostic model featuring real-time analysis of brain CT imagesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,387,866June 1, 2022May 31, 2027DUNN, TIMOTHY WILLIAMreporter.nih.gov
Toxicology and Efficacy Studies of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2023$2,380,552September 18, 2023August 31, 2026SUN, MIAOreporter.nih.gov
A randomized controlled trial of an innovative in-home rehabilitation program for persons with TBI and their families: Home-based Occupational-therapy and Management of the Environment (HOME for Us)NIHNational Institute of Nursing Research2021 to 2024$2,379,845September 15, 2020June 30, 2026MORIARTY, HELENE JOYreporter.nih.gov
Mechanisms of Circadian and Synaptic Dysfunction After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2022$2,366,184June 1, 2022May 31, 2025WHALEN, MICHAEL Jreporter.nih.gov
Traumatic Axonopathy in the CNS as Wallerian degenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,365,581January 1, 2021November 30, 2026KOLIATSOS, VASSILIS Ereporter.nih.gov
3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,352,214September 2, 2021June 30, 2026PARR, ANN Mreporter.nih.gov
Detect: A novel device to assess how HIV affects neurocognitive decline and postural instability in older adults at risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$2,349,852February 15, 2019November 30, 2024MOORE, RAEANNE CRISTINEreporter.nih.gov
Enhancing recovery of lower limb function after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,341,089September 1, 2024August 31, 2026RENNAKER, ROBERT Lreporter.nih.gov
PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,336,406September 20, 2014June 30, 2026KANAI, ANTHONY JOHNreporter.nih.gov
Assessing Diffusion MRI Metrics for Detecting Changes of Synaptic Density in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$2,313,017September 15, 2023May 31, 2028WU, YU-CHIENreporter.nih.gov
Extrinsic Mechanisms Governing Injury-Induced Axon DegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,312,486August 15, 2015March 31, 2026DEPPMANN, CHRISTOPHER Dreporter.nih.gov
Pulsed laser therapy in an asymptomatic head injury-accelerated Alzheimer's modelNIHNational Institute of Neurological Disorders and Stroke2024$2,309,898September 17, 2024August 31, 2027ZHANG, QUANGUANGreporter.nih.gov
Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric SymptomsNIHNational Institute of Neurological Disorders and Stroke2021$2,309,451September 15, 2021August 31, 2024ALOSCO, MICHAELreporter.nih.gov
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021$2,302,768April 1, 2021March 31, 2024ZHAO, ZHENreporter.nih.gov
Reprogramming proinflammatory microglia by restoring mitochondrial functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,300,527July 1, 2020June 30, 2025POLSTER, BRIAN Mreporter.nih.gov
Contribution of Innate Immune Receptors to Neurological Dysfunction After Traumatic Brain Injury: Mechanisms and Therapeutic ImplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,291,943April 1, 2021March 31, 2027SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
The mechanism of allosteric modulation of glutamate transportersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,281,652December 1, 2019November 30, 2025MORTENSEN, ANDREIA C Kreporter.nih.gov
Optimizing Collaborative Care for Youth with Persistent Post-Concussive SymptomsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,275,364February 3, 2017April 30, 2028MC CARTY, CAROLYN Areporter.nih.gov
Mechanisms of oxysterol-induced oligodendrogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,255,433December 15, 2019November 30, 2024BENNER, ERIC Jreporter.nih.gov
Precision Medicine Approach: Using genomic information to guide TBI treatmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,251,700January 15, 2020December 31, 2025GOMEZ-PINILLA, FERNANDOreporter.nih.gov
Exploring the EphB2-NMDA receptor interaction in spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,249,630September 1, 2018June 30, 2029LEPORE, ANGELO C.reporter.nih.gov
Improving Outcomes for Care Partners of Persons with Traumatic Brain InjuryNIHNational Institute of Nursing Research2021 to 2024$2,247,328September 27, 2012November 30, 2025CARLOZZI, NOELLE E.reporter.nih.gov
Stabilizing the Tripartite Synaptic Complex Following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,237,377February 1, 2017December 31, 2027LIEBL, DANIEL JONreporter.nih.gov
MRI Measurement of the Mechanical Vulnerability of the BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,235,019September 15, 2019July 31, 2025BAYLY, PHILIP Vreporter.nih.gov
The Function and Mechanisms of Autophagy in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022$2,231,793June 1, 2016May 31, 2025WU, JUNFANGreporter.nih.gov
Autocrine Action of Elevated FGF-21 Contributing to Skeletal Muscle Atrophy in Response to Mitochondrial DysfunctionNIHNational Institute on Aging2021 to 2025$2,229,824August 15, 2021April 30, 2027ROWE, GLENN CAMERONreporter.nih.gov
Spinal Effects of Cortical Stimulation: Mechanisms and Functional ImpactNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,222,374September 30, 2019July 31, 2025WOLPAW, JONATHAN RICKELreporter.nih.gov
Heading and Soccer: Understanding Cognitive Risks, Benefits, and the Potential Mediating Role of White MatterNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,220,345August 1, 2022July 31, 2027LIPTON, MICHAEL LAWRENCEreporter.nih.gov
Spatiotemporal Molecular Substrates of TBI at Single Cell ResolutionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,218,963July 1, 2020March 31, 2026YANG, XIAreporter.nih.gov
Limb coordination during locomotion before and after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,207,839February 15, 2020January 31, 2026RYBAK, ILYA Areporter.nih.gov
Development of KCC2 Neuromodulators to Treat Paralysis After Spinal Cord Injury.NIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,200,694March 1, 2022February 28, 2025STANICKA, JOANNAreporter.nih.gov
Neuroprotective B Cell Immunotherapy for Contusion Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,197,906May 1, 2021February 28, 2027SIRBULESCU, RUXANDRA Freporter.nih.gov
Improving intracortical control of reaching after paralysisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,197,457July 1, 2020June 30, 2026TAYLOR, DAWN MARIEreporter.nih.gov
Development of Molecular Probe Inhibitors of Pathogenic, Cytosolic Cathespin B in Traumatic Brain Injury and Alzheimers Disease NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,197,366August 1, 2019June 30, 2025HOOK, VIVIAN Y. Hreporter.nih.gov
Cellular signaling mechanisms that drive persistent hyperexcitability in nociceptorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,193,348August 15, 2015July 31, 2030DESSAUER, CARMEN W.reporter.nih.gov
Assessing the effects of peripheral immune activation on the NVU following TBI using a vascularized and perfused human blood/BBB modelNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,181,059September 15, 2021August 31, 2026AGALLIU, DRITANreporter.nih.gov
Wireless Implantable COrtical Neuroprosthetic System (W-ICONS)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,177,031June 1, 2023May 31, 2026TENORE, FRANCESCO Vreporter.nih.gov
Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolismNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,169,572September 1, 2020August 31, 2025PARK, JAE MOreporter.nih.gov
Chronic and Evolving Inflammation after Traumatic Brain Injury: Microglial Priming and Neuropsychiatric ComplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,169,210April 1, 2021March 31, 2026GODBOUT, JONATHAN Preporter.nih.gov
Rewiring the Injured Brain with GABA ProgenitorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,163,757February 15, 2016March 31, 2027HUNT, ROBERT Freporter.nih.gov
Adaptation of internal motor copy circuits in recovery after spinal cord injury.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,157,453August 1, 2020June 30, 2025SMITH, GEORGE Mreporter.nih.gov
Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2022$2,152,606August 1, 2016August 31, 2025RANUM, LAURA P.Wreporter.nih.gov
Endocannabinoids in neurodegenerative diseasesNIHNational Institute of Neurological Disorders and Stroke2023$2,151,868June 15, 2012April 30, 2026CHEN, CHUreporter.nih.gov
Retinal eye-tracking as a prognostic tool for traumatic brain injury and concussionNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,150,115July 16, 2016August 31, 2025SHEEHY, CHRISTY KATHLEENreporter.nih.gov
Transforming Research And Clinical Knowledge in Geriatric Traumatic Brain Injury (TRACK-GERI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,145,667September 1, 2019May 31, 2025MANLEY, GEOFFREY Treporter.nih.gov
Pediatric Chronic Headache and COVID-19: Use of Machine Learning and Biobehavioral Analysis to Classify Headache Mechanism and Optimize Treatment Course.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,140,031August 18, 2022May 31, 2027HOLMES, SCOTTreporter.nih.gov
Implementation Fidelity and Benefits of the Critical Care Pediatric Guideline Adherence and Outcomes Program in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,137,509January 1, 2019December 31, 2024VAVILALA, MONICA Sreporter.nih.gov
Vestibular System Function Following Blast ExposureNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,126,775March 1, 2021February 28, 2027DICKMAN, J DAVIDreporter.nih.gov
A Randomized Controlled Trial of BETTER, A Transitional Care Intervention, for Patients with Traumatic Brain Injury and Their FamiliesNIHNational Institute of Nursing Research2023 to 2025$2,125,541May 19, 2023February 28, 2028OYESANYA, TOLU O.reporter.nih.gov
Biomarker Signature to Predict the Persistence of Post-Traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,111,462September 1, 2019July 31, 2025CHONG, CATHERINE DANIELAreporter.nih.gov
SNSPD-DCS at 1064 nm for non-invasive monitoring of cerebral perfusion and intracranial pressure in the ICUNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$2,109,015September 1, 2023August 31, 2028FRANCESCHINI, MARIA ANGELAreporter.nih.gov
Neurobehavioral consequences of Mild Traumatic Brain Injury and addiction risk: a cotwin-control studyNIHNational Institute on Drug Abuse2023 to 2025$2,093,963September 30, 2023July 31, 2028ANOKHIN, ANDREY P.reporter.nih.gov
Exploring Mechanisms Underlying SCF+G-CSF-Enhanced Recovery in ChronicTBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,093,761April 1, 2021March 31, 2027ZHAO, LI-RUreporter.nih.gov
A physiologically relevant pre-clinical drug screening platform for Alzheimer's Disease and Traumatic Brain Injury with integrated stretchable microelectrodesNIHNational Institute on Aging2022 to 2025$2,090,923September 30, 2022November 30, 2026GRAUDEJUS, OLIVERreporter.nih.gov
Development of an MRI Template & Neuroimaging Biomarkers of the Pediatric Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,087,756March 15, 2020January 31, 2026MOHAMED, FEROZE Breporter.nih.gov
Mechanisms of locomotor rhythm generation in rodent spinal cordNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,076,605September 30, 2022July 31, 2027DOUGHERTY, KIMBERLY Jreporter.nih.gov
Analytical Validation of Portable Devices for Detection of Traumatic Brain Injury BiomarkersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,066,291August 1, 2021April 30, 2027WU, NIANQIANGreporter.nih.gov
Optimizing Environmental Enrichment to Model Preclinical NeurorehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,054,372May 15, 2014June 30, 2026KLINE, ANTHONY E.reporter.nih.gov
The Contribution of Age-Related Taupahtoies to Alzheimer's Disease-SupplementNIHNational Institute on Aging2021 to 2022$2,048,437September 30, 2018August 31, 2023MCKEE, ANN C.reporter.nih.gov
Cervical Epidural Stimulation and Respiratory Motor PlasticityNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,047,568July 1, 2021June 30, 2027DALE, ERICA ARDENreporter.nih.gov
BMAL1/ARNTL plays a critical, non-circadian role in secondary tissue damage after contusive SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,043,009August 15, 2020May 31, 2026HETMAN, MICHALreporter.nih.gov
Cell Specific RIPK3 Signaling After Traumatic Brain Injury in MiceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,035,353April 1, 2021December 31, 2026WHALEN, MICHAEL Jreporter.nih.gov
Neurobehavioral, cognitive, and mechanistic effects of intranasally administered neural stem cells and environmental enrichment after cortical impact injury in ratsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,032,869September 1, 2021August 31, 2025KLINE, ANTHONY E.reporter.nih.gov
Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical InjuriesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,031,527July 1, 2021June 30, 2027CHEN, HAN-CHIAO ISAACreporter.nih.gov
Deep Brain Stimulation of the Cerebellar Dentate Nucleus to Enhance Chronic, Post-Traumatic Brain Injury RehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,019,158July 1, 2020June 30, 2026BAKER, KENNETH Breporter.nih.gov
Access-H20: Sensor driven smart faucet to enable and empower independent drinking and grooming for individuals impacted by spinal cord injuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$2,012,340September 25, 2023August 31, 2025WADDELL, JOHN STEVENreporter.nih.gov
Nano-Pulsed Optoacoustic Neuromodulation for Reducing Traumatic Brain Injury-Driven Neuropathology and Improving Cognitive OutcomeNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,007,911June 1, 2022May 31, 2027MICCI, MARIA-ADELAIDEreporter.nih.gov
3T MRI scanner for Advanced Brain ImagingNIHOffice of the Director, National Institutes of Health2023$2,000,000March 15, 2023March 14, 2026TROUARD, THEODORE Preporter.nih.gov
MicroRNA Therapeutics for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,987,816February 15, 2020January 31, 2026LIU, DAZHI JEFFreporter.nih.gov
Neuroinflammation in Wallerian Degeneration and Regeneration: Neutrophils Play a Primary Role as PhagocytesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,986,349August 1, 2020October 31, 2025ZIGMOND, RICHARD Ereporter.nih.gov
Embryonic Stem Cell Therapy after Cervical Contusion SCI in NHPsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,982,569February 1, 2023January 31, 2028ROSENZWEIG, EPHRON SOLOMONreporter.nih.gov
Mapping neural ensemble computations to biological circuitry in motor control and decision making - Resubmission - 1NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,976,041August 15, 2021May 31, 2027KAUFMAN, MATTHEW TYLERreporter.nih.gov
Immunometabolic regulation after CNS injuryNIHNational Institute of Neurological Disorders and Stroke2023$1,975,262September 21, 2023August 31, 2026DHANDAPANI, KRISHNAN M.reporter.nih.gov
Role of Peripheral Inflammation in TBI PathobiologyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,973,761February 1, 2022January 31, 2027DASH, PRAMOD Kreporter.nih.gov
L-selectin shedding as a novel therapeutic strategy to mitigate acute secondary damage after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,964,636August 1, 2021June 30, 2027MCCREEDY, DYLAN A.reporter.nih.gov
HYBRID-FES EXERCISE TO PREVENT CARDIOPULMONARY DECLINES IN ACUTE HIGH LEVEL SCINIHNational Heart, Lung, and Blood Institute2021 to 2024$1,963,199August 1, 2013June 30, 2026TAYLOR, J ANDREWreporter.nih.gov
Optimized Sodium MR Imaging at Clinical Field Strength to Study in vivo Sodium Signal in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,962,114April 25, 2023March 31, 2028LUI, YVONNE Wreporter.nih.gov
Clinical readiness of Uzap - the minimally invasive Overactive Bladder treatmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,959,549September 20, 2021June 30, 2025STERN, ROGERreporter.nih.gov
Developing a kinase inhibitor drug to treat spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,959,367February 4, 2022January 31, 2027AL ALI, HASSANreporter.nih.gov
Multi-modal machine learning detection and tracking of traumatic brain injury neurodegeneration and its differentiation from Alzheimer's diseaseNIHNational Institute on Aging2022 to 2023$1,958,406September 30, 2018July 31, 2025LUKIC, ANA Sreporter.nih.gov
Impact of TBI and Cognitive Decline on Alzheimer's Disease Brain-Derived Exosome CargoNIHNational Institute on Aging2023$1,948,168June 1, 2023May 31, 2026RISSMAN, ROBERTreporter.nih.gov
Driving after Concussion: Examination of the Adolescent Brain and BehaviorsNIHNational Institute of Nursing Research2021 to 2024$1,943,796April 3, 2020January 31, 2026MCDONALD, CATHERINE CLAIREreporter.nih.gov
Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related DementiasNIHNational Institute of Neurological Disorders and Stroke2023$1,940,666June 1, 2023May 31, 2025ALOSCO, MICHAELreporter.nih.gov
Mechanisms and Therapeutic Strategies for Post-traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,934,562July 15, 2020June 30, 2025PORRECA, FRANKreporter.nih.gov
Noninvasive transcranial detection of intracranial hemorrhage using a tri-coil handheld portable eddy current damping imaging deviceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,924,473January 15, 2021December 31, 2025ZADA, GABRIELreporter.nih.gov
Assessing the effects of peripheral immune activation on the NVU following TBI using avascularized and perfused human blood/BBB model.NIHNational Heart, Lung, and Blood Institute2021 to 2022$1,914,338September 15, 2021August 31, 2023AGALLIU, DRITANreporter.nih.gov
Comprehensive Quantitative Profiling of Cellular Alterations Caused by InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,911,936July 1, 2019March 31, 2026ROYSAM, BADRINATHreporter.nih.gov
Targeting Protease Activated Receptor 1 for Repair of the Injured Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,911,280September 1, 2021August 31, 2025SCARISBRICK, ISOBEL Areporter.nih.gov
Development of an EMG-controlled BCI for biomimetic control of hand movement in humansNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,909,196September 18, 2023August 31, 2028MILLER, LEEreporter.nih.gov
Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST StudyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,905,236June 1, 2023May 31, 2028KRISHNAMOORTHY, VIJAYreporter.nih.gov
The molecular intersection of tau, TBI, and PERKNIHNational Institute on Aging2021 to 2025$1,898,625September 30, 2021May 31, 2026ABISAMBRA, JOSE FRANCISCOreporter.nih.gov
Optogenetics to improve hand function after spinal cord injury.NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,895,487September 15, 2020July 31, 2025MORITZ, CHET T.reporter.nih.gov
Transformation of Dormant Spinal Networks to Mitigate Symptoms of Neurogenic BladderNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,881,342August 15, 2021July 31, 2024GAD, PARAGreporter.nih.gov
Identifying Novel Molecular Targets for Chronic SCINIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,880,008March 15, 2015November 30, 2026WU-HUBER, JIAQIANreporter.nih.gov
Comprehensive White-matter Microstructure-informed Analytical Methods to Elucidate Neurobiological Mechanisms of Sports-related Concussion (SRC)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,877,939April 15, 2020August 31, 2025WU, YU-CHIENreporter.nih.gov
Axonal Varicosity Dynamics in Central Neuron Mechanosensation and InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,876,746June 15, 2016March 31, 2027GU, CHENreporter.nih.gov
Functional Diversity of Reactive Astrocytes in Spinal Cord RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,862,775April 1, 2021March 31, 2027CHEN, MEIFANreporter.nih.gov
Reprogramming reactive glial cells into functional new neurons after SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,850,333August 1, 2020February 28, 2025WU, WEIreporter.nih.gov
MRI Markers of Feedback Timing during Learning in Individuals with TBI with and without Clinical DepressionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,849,868April 1, 2021January 31, 2027DOBRYAKOVA, EKATERINAreporter.nih.gov
Novel Carbon Nanozyme Mechanisms for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,833,893September 1, 2015March 31, 2026KENT, THOMASreporter.nih.gov
Mechanisms of Action Contributing to Decrease Spasticity and Improve Motor Recovery with Repeated Transcutaneous Stimulation After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,832,390December 15, 2020November 30, 2026COTE, MARIE-PASCALEreporter.nih.gov
Investigating the Effects of Spinal Cord Injury and Rehabilitative Training on Corticospinal Circuits Controlling Contextual Opioid Analgesic ToleranceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,829,756September 1, 2025November 30, 2025CAFFERTY, WILLIAM B.reporter.nih.gov
Defining the remote effects of cortical spreading depolarizations on hippocampus after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,824,305February 15, 2023January 31, 2028NGWENYA, LAURA BENJAMINreporter.nih.gov
Dissecting Connectivity and Function of Transplanted Interneurons in the Injured Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,824,063January 1, 2021November 30, 2025DULIN, JENNIFER Nreporter.nih.gov
Central Thalamic Deep Brain Stimulation to Regulate Arousal and CognitionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,821,751April 1, 2020March 31, 2025BAKER, JONATHAN Lreporter.nih.gov
Pediatric Mild Traumatic Brain Injury and the ABCD Study: A Prospective Behavioral, Psychiatric, Neurocognitive, Imaging, and Genetic InvestigationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,820,333June 15, 2022April 30, 2027MAX, JEFFREY EDWINreporter.nih.gov
Biomarkers in the Hyperbaric Oxygen in Brain Injury Treatment TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,818,192September 15, 2020August 31, 2027KORLEY, FREDERICK KOFIreporter.nih.gov
Minimally Invasive Cerebral Blood Flow and Oxygenation Monitoring for Intracranial HypertensionNIHNational Institute of Neurological Disorders and Stroke2022$1,814,829September 20, 2022March 31, 2024FLOYD, THOMAS FREDERICKreporter.nih.gov
Regulation of Viscerosensory Sympathetic Reflexes: The Role of Diet-Derived Lipid Mediators.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,802,692April 1, 2020March 31, 2026O'LEARY, DONAL Sreporter.nih.gov
Investigating the role of CD44 and immune-neuro signaling mechanisms in neural stem cell responses after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,800,698June 21, 2022May 31, 2027ANDERSON, AILEEN Jreporter.nih.gov
Role of Sleep Disruption after mTBI as a Driver of Chronic Post-traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,798,407July 1, 2023June 30, 2028ILIFF, JEFFREY Jreporter.nih.gov
The Role of a Pair of MAP3Ks in the Multicellular Response to Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,798,146May 1, 2015April 30, 2025ZHENG, BINHAIreporter.nih.gov
A Risk Stratification Model for Health and Academic Outcomes in Children with Concussion Based on Novel Symptom Trajectory TypologiesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,797,265March 1, 2023February 29, 2028REUTER-RICE, KARINreporter.nih.gov
Pre-clinical validation of 3D-printed nerve conduits for pediatric peripheral nerve repairNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,788,090June 27, 2023March 31, 2028CHEN, SHAOCHENreporter.nih.gov
Enhanced Mitochondrial Viability via Engineered Hyrdogels for Intrathecal Spinal Cord DeliveryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,786,283September 30, 2020June 30, 2025PATEL, SAMIRKUMARreporter.nih.gov
Crucial spinal circuit changes that mediate locomotor benefits and deficits following combined therapies after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,784,512July 1, 2018August 31, 2030DOUGHERTY, KIMBERLY Jreporter.nih.gov
A Novel Therapeutic to Promote Corneal RepairNIHNational Eye Institute2023 to 2025$1,779,892September 30, 2023August 31, 2026KRAMER, ADAM HILDYARDreporter.nih.gov
Targeting Lipid Clearance Pathways to Promote Repair after SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,779,784September 1, 2012April 30, 2028LEE, JAE Kreporter.nih.gov
Connecting Alzheimer's Disease to Traumatic Synaptic NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,775,841May 1, 2022March 31, 2028KUMMER, TERRANCE Treporter.nih.gov
Lasting Impacts: Dynamic, Fully Natural Bioprinted 3D Human Neurovascular Biomimetic Model to Study Traumatic Brain Injury PathophysiologyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,766,629September 15, 2021December 31, 2026MOYA, MONICA LIZETreporter.nih.gov
Role of Neuronal p38 MAPK After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,766,593September 30, 2020June 30, 2026WOOD, LEVI BENJAMINreporter.nih.gov
Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic PlasticityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,761,885December 1, 2021November 30, 2026PAZ, JEANNE Treporter.nih.gov
Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass SpectrometryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,756,092July 1, 2012July 31, 2028BAYIR, HÜLYAreporter.nih.gov
Glial metabolic status regulates axon regeneration in the central nervous systemNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,755,946February 15, 2023March 31, 2028SONG, YUANQUANreporter.nih.gov
Anti-microbial platelet-like-particles to treat internal bleeding and augment subsequent healingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,752,994April 1, 2023March 31, 2027BROWN, ASHLEY CARSONreporter.nih.gov
MRI-Derived Neuromuscular Signatures to Predict Surgical Response in Degenerative Cervical MyelopathyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,750,410May 15, 2023January 31, 2028WEBER, KENNETH ARNOLDreporter.nih.gov
Structural and functional imaging markers in Degenerative Cervical MyelopathyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,734,098September 1, 2023July 31, 2028SMITH, ZACHARYreporter.nih.gov
Multi-channeled Bridges for Promoting Chronic Spinal Cord RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,728,749September 1, 2020July 31, 2025SHEA, LONNIE Dreporter.nih.gov
Integrated Next-generation RF Transmit, Receive and B0 shimming coil system for brain and spinal cord MRI at 7 TeslaNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$1,724,219August 15, 2022May 31, 2027YAN, XINQIANGreporter.nih.gov
Mesenchymal Stem Cell Derived Extracellular Vesicles for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,721,728June 15, 2018June 30, 2030SHETTY, ASHOK Kreporter.nih.gov
Development of Novel sgp130-Fc Bioconjugates for TBINIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,721,185February 15, 2023August 31, 2027HASKINS, WILLIAM Ereporter.nih.gov
Human Brain Interferometers for Better Blood Flow MonitoringNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,720,177April 13, 2021December 31, 2024SRINIVASAN, VIVEK JAYreporter.nih.gov
Effects of Head Impact Exposure During Contact Sport on Middle School and High School AthletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,718,817April 1, 2019June 30, 2025WANG, YANGreporter.nih.gov
Hemodynamic basis for secondary cervical grey matter tissue loss after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,715,566May 15, 2021September 1, 2025KHAING, ZIN Zreporter.nih.gov
Synaptic Vesicular Alterations after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,715,310August 15, 2022June 30, 2027CARLSON, SHAUNreporter.nih.gov
Multipronged approach to diminish sympathetic hyperreflexia and ensuing cardiovascular and immune dysfunction after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,714,182April 1, 2022March 31, 2027TOM, VERONICA JEANreporter.nih.gov
Rapid saliva test for diagnosis of mTBI and prognosis of Persistent Post-conccussion Symptoms (PPCS) in children and adultsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,698,783September 17, 2021August 31, 2024SOUTHERN, SARKA OLIVERAreporter.nih.gov
Neuronal IL-1R1 Signaling in Mild Closed Head InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,696,702July 1, 2022May 31, 2027BACHSTETTER, ADAM Dreporter.nih.gov
Axonal Pathology and TBI-Related Neurodegeneration (TReND)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,695,531April 1, 2016December 31, 2027SMITH, DOUGLAS HAMILTONreporter.nih.gov
Immune-modifying nanoparticles for the treatment of traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,685,137August 1, 2020April 30, 2025KESSLER, JOHN Areporter.nih.gov
INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRINGNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,682,280January 15, 2022November 30, 2026COHEN, AKIVA Sreporter.nih.gov
Development of a Colorimetric Sensor for Detection of Cerebrospinal Fluid LeaksNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,680,880January 2, 2023December 31, 2025HU, MINreporter.nih.gov
Identifying Potential Therapeutic Targets for Abusive Head TraumaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,679,245September 1, 2020August 31, 2025COSTINE-BARTELL, BETH Areporter.nih.gov
Solid-state nanopores and silicon nanomembranes for ultrasensitive protein biomarker detectionNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,678,043June 15, 2021March 31, 2026MCGRATH, JAMES Lreporter.nih.gov
Poly-Matching Causal Inference for Assessing Multiple Acute Medical Managements of Pediatric Traumatic Brain InjuriesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,673,547February 1, 2023January 31, 2028XIANG, HENRYreporter.nih.gov
Molecular Dissection of Proprioceptor Subclass IdentityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,668,554March 1, 2019November 30, 2029DE NOOIJ, JORIENEreporter.nih.gov
Improving Patient Classification and Outcome Measurement in Traumatic Brain Injury (TBI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,666,852May 15, 2019March 31, 2026NELSON, LINDSAYreporter.nih.gov
Traumatic brain injury and aging: targeting the cholinergic system for deficits in sustained attention and executive functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,665,105August 1, 2024April 30, 2026BONDI, CORINA OANAreporter.nih.gov
Potency and contribution of zebrafish progenitors during innate spinal cord repairNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,662,051September 30, 2019January 31, 2030MOKALLED, MAYSSA H.reporter.nih.gov
Impact of microbiota-derived metabolites on traumatic brain injury-related neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,660,221January 1, 2023December 31, 2027SIMON, DENNIS WILLIAMreporter.nih.gov
Inter-System Closed-Loop Control of Locomotor and Bladder Function in Individuals with Acute Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022$1,639,225September 15, 2020September 29, 2023ANGELI, CLAUDIAreporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2025$1,638,533September 1, 2022August 31, 2027DAMS-O'CONNOR, KRISTENreporter.nih.gov
Priming with High-Frequency Trans-spinal Stimulation to Augment Locomotor Training Benefits in Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,635,752June 9, 2020December 31, 2024KNIKOU, MARIAreporter.nih.gov
Hypertension, Blood Pressure Targets, and Alzheimer’s Disease and Dementia Risk and Disparities among Nationally Representative US VeteransNIHNational Institute on Aging2024 to 2025$1,629,636September 30, 2024June 30, 2029YAFFE, KRISTINEreporter.nih.gov
The role of macrophage metabolism and age in recovery from spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,629,067June 1, 2023May 31, 2028GENSEL, JOHN Creporter.nih.gov
The Role of ApoE in Injury-Induced NeurogenesisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,627,788January 1, 2017June 30, 2027KERNIE, STEVEN GERARDreporter.nih.gov
Microglial process convergence following brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,627,616August 1, 2023July 31, 2027LAFRENAYE, AUDREY Dreporter.nih.gov
Transformation of Paraplegic Paralysis to Overground Stepping in HumansNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,626,665September 30, 2019August 31, 2025OVECHKIN, ALEXANDER VLADIMIROVICHreporter.nih.gov
Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric SymptomsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,626,188September 15, 2021August 31, 2027ALOSCO, MICHAELreporter.nih.gov
Longitudinal Sub-thalamic Structure and Functional Alterations in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,619,153July 15, 2018May 31, 2025ZHUO, JIACHENreporter.nih.gov
Dopaminergic Mechanisms Underlying Behavioral Deficits Following Mild TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,616,918April 1, 2020February 28, 2026RAGHUPATHI, RAMESHreporter.nih.gov
The Therapeutic Potential of Cold Stored Platelets in Regulating Vascular Instability in TraumaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,615,000August 5, 2020June 30, 2025PATI, SHIBANIreporter.nih.gov
Glial cell responses promote spinal cord repair in zebrafishNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,613,603April 1, 2022March 31, 2027MOKALLED, MAYSSA H.reporter.nih.gov
Targeting aging genes and pathways to promote optic nerve regenerationNIHNational Eye Institute2021 to 2024$1,612,937January 1, 2020December 31, 2025WAN, MEIreporter.nih.gov
Regulation of SCI-induced pain by macrophages and exerciseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,610,456September 18, 2017June 30, 2028DETLOFF, MEGAN Rreporter.nih.gov
Gravida traumatic brain injury (TBI) impacts neurodevelopment of the offspringNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,608,657September 1, 2023May 31, 2026LIFSHITZ, JONATHANreporter.nih.gov
MRE elastography-based detection of impaired skull-brain decoupling after repetitive subconcussive sports impactNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,605,477September 15, 2019April 30, 2030YIN, ZIYINGreporter.nih.gov
Mild traumatic brain injury alters interneuron structure and functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,597,977September 1, 2011March 31, 2029JACOBS, KIMBERLE MAEreporter.nih.gov
Transcutaneous Direct Current Motor Nerve Block for SpasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,597,570April 1, 2021March 31, 2026VRABEC, TINA LOUISEreporter.nih.gov
An innovative device for management of neuropathic pain after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024$1,594,319September 19, 2024August 31, 2026LI, SHENGreporter.nih.gov
The role of monocyte and microglia interaction in the evolution of traumatic brain injury-induced neurodegenerationNIHNational Institute of General Medical Sciences2021 to 2023$1,593,117September 1, 2019July 31, 2025SCHWULST, STEVEN Jreporter.nih.gov
Single stage surgical intervention for treatment of severe traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,588,284March 1, 2022June 30, 2024DETAMORE, MICHAEL S.reporter.nih.gov
Calibrating Transcutaneous Spinal Stimulation for Spasticity, Pain, and Motor Function in SCINIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,587,367August 27, 2021April 30, 2027FIELD-FOTE, EDELLE C.reporter.nih.gov
Pilot Clinical Study to Assess Safety and Efficacy of External Ventricular Drainage with Cerebrospinal Fluid Water Removal Osmotherapy for Traumatic Brain Injury-Induced Cerebral EdemaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,570,119June 15, 2022January 31, 2026HOFMEISTER, JOEreporter.nih.gov
NOX2 drives microglia-dependent neurodegeneration after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,565,910August 1, 2022July 31, 2027STOICA, BOGDAN ADRIANreporter.nih.gov
Role of proNGF-p75 signaling in the bladder control after spinal cord injuryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,553,061February 18, 2019January 31, 2026GAO, JIEreporter.nih.gov
Chemogenetic afferent modulation to understand spinal cord circuit function and plasticity post injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,552,739September 1, 2020August 31, 2026SPENCE, ANDREWreporter.nih.gov
In vivo MRI Measures of Brain Metabolism in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,551,605May 1, 2022April 30, 2027TU, TSANG-WEIreporter.nih.gov
Clinical Evaluation of NoGo Trap Therapy in Chronic SCINIHNational Institute of Neurological Disorders and Stroke2021$1,545,531September 15, 2020April 10, 2023SMITH, ERIKAreporter.nih.gov
Optimizing the restoration and rehabilitation of function using cortically-controlled FES following SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,545,295July 1, 2019April 30, 2025TRESCH, MATTHEWreporter.nih.gov
Minocycline Plus N-Acetylcysteine Improves Brain Structure and Function After Experimental Brain Injury with Clinically Useful Time WindowsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,539,997February 1, 2019November 30, 2024BERGOLD, PETER Jreporter.nih.gov
Bioengineering of highly effective AAV vectors for noninvasive gene delivery to the nervous systemNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,533,488April 1, 2022March 31, 2027LI, SHUXINreporter.nih.gov
Effects of activity dependent plasticity on recovery of bladder and sexual function after human spinal cord injuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,528,743September 23, 2014July 31, 2025HUBSCHER, CHARLES H.reporter.nih.gov
Diffuse Optics for Pediatric Hydrocephalus ManagementNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,528,451February 1, 2020January 31, 2026BAKER, WESLEYreporter.nih.gov
Mechanisms of Chronic Progressive Axon Degeneration Following TBINIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,525,713August 15, 2022June 30, 2027SMITH, DOUGLAS HAMILTONreporter.nih.gov
Influence of thalamic IL-33 signaling in aging-associated exacerbation of cognitive impairment after brain injury via microglial dysfunction and tau pathologyNIHNational Institute on Aging2022 to 2024$1,522,144September 15, 2022August 31, 2025KANO, SHINICHIreporter.nih.gov
Epigenetic Age and Patient Outcomes after Severe Traumatic Brain InjuryNIHNational Institute on Aging2024 to 2025$1,522,029August 15, 2024April 30, 2029CONLEY, YVETTE Preporter.nih.gov
Transcriptional regulatory mechanisms of vertebrate regenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,517,829July 15, 2017December 31, 2027WILLS, ANDREA ELIZABETHreporter.nih.gov
Multipronged approach to promote functional axonal regeneration in the spinal cord after injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,511,770January 1, 2024December 31, 2025TOM, VERONICA JEANreporter.nih.gov
Preclinical Efficacy and Safety Evaluation of Oral AST-004 for Moderate Traumatic Brain Injury (TBI)NIHNational Institute of Neurological Disorders and Stroke2025$1,499,886June 12, 2025May 31, 2027LISTON, THEODORE Ereporter.nih.gov
Injury-Induced Alterations in Limbic Functional CircuityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,496,917April 1, 2003April 30, 2024COHEN, AKIVA Sreporter.nih.gov
Effects of Tamoxifen in skeletal muscle recovery after spinal cord injury and mechanisms activated by the drugNIHNational Institute of General Medical Sciences2022 to 2025$1,494,500April 1, 2022March 31, 2027MIRANDA, JORGE DAVIDreporter.nih.gov
Network Dysfunction and Neuromodulation following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,494,401April 1, 2017January 31, 2028WOLF, JOHN ALLENreporter.nih.gov
Understanding the age-dependent mitochondrial function in astrocytes after spinal cord injury via bi-directional manipulation of activityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,492,519August 1, 2022July 31, 2027HOOK, MICHELLE Areporter.nih.gov
Mechanisms and Therapeutic Targeting of Chronic Neuroinflammation in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,489,949March 1, 2022February 28, 2027BRANN, DARRELL Wreporter.nih.gov
Identifying novel regenerative treatments for CNS injury in adult mammalsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,482,069August 1, 2023July 31, 2028LI, SHUXINreporter.nih.gov
Dynamic temporal regulation of astrocyte coupling to shape neuronal activity during acquired epilepsy developmentNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,478,759May 15, 2022February 28, 2027ROBEL, STEFANIEreporter.nih.gov
Role of ASC in TBI-Mediated Systemic Inflammation.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,476,248December 1, 2019November 30, 2025KEANE, ROBERT Wreporter.nih.gov
SCI-induced deficits in antiviral immunity: The role of sTNF.NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,475,910September 30, 2019June 30, 2025TOM, VERONICA JEANreporter.nih.gov
Community-Based Organizations and Development of Implementation Strategies for Brain Injury Screening Resulting from Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,471,674July 15, 2023May 31, 2027RAJARAM, SHIREEN SHEELAreporter.nih.gov
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,466,564April 1, 2021March 31, 2026ZHAO, ZHENreporter.nih.gov
Exploring the therapeutic mechanisms of proinflammatory myelin-laden macrophages retention in the injured spinal lesion coreNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,466,304February 15, 2022January 31, 2027NOWAKOWSKI, RICHARD Sreporter.nih.gov
Natural History of Shoulder Pathology in Wheelchair UsersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,464,755April 22, 2022June 30, 2027MORROW, MELISSA M.reporter.nih.gov
The organization of spinal neurons following spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,460,535February 19, 2022January 31, 2027THOMPSON, CHRISTOPHER KEITHreporter.nih.gov
Reducing Infection Susceptibility by Immune Function Restoration in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,459,520July 1, 2020June 30, 2025SCHWAB, JANreporter.nih.gov
Subtle Motor Functioning and Functional Connectivity in Youth Medically Cleared after Mild TBINIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,456,488February 13, 2018January 31, 2025SUSKAUER, STACY JENNIFER MARCUSreporter.nih.gov
Inter-System Closed-Loop Control of Locomotor and Bladder Function in Individuals with Acute Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024$1,454,762September 15, 2020June 30, 2027ANGELI, CLAUDIAreporter.nih.gov
Timing Of Exercise In Concussed Rat AthletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,449,648March 1, 2019February 28, 2025PRINS, MAYUMI LYNNreporter.nih.gov
Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2NIHNational Institute of General Medical Sciences2021 to 2023$1,448,376May 1, 2020January 31, 2025HANDEL, TRACY Mreporter.nih.gov
Mechanisms of type I interferon neuropathology following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,442,235September 19, 2023July 31, 2028NEWELL, ELIZABETHreporter.nih.gov
Therapeutic Targeting of Monoacylglycerol Lipase After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,436,743August 1, 2020April 30, 2026VAIBHAV, KUMARreporter.nih.gov
MicroRNA Function During Neuronal Reprogramming in Treating Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,436,743January 1, 2021June 30, 2025LI, HEDONGreporter.nih.gov
Paired Stimulation Plasticity for Motor RecoveryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$1,431,959September 1, 2025August 31, 2028PEREZ, MONICA Areporter.nih.gov
Can [18F]3F4AP Detect Brain Demyelination? Evaluation of Novel PET Tracer in Nonhuman Primates and HumansNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,426,088December 15, 2019November 30, 2025BRUGAROLAS, PEDROreporter.nih.gov
MB-SWIFT as a novel approach for simultaneous functional imaging of the brain and spinal cordNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,423,796January 1, 2023November 30, 2026MICHAELI, SHALOMreporter.nih.gov
Cerebral Mechanisms of Vulnerability Following Female Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,420,105August 1, 2020April 30, 2026GRECO, TIFFANYreporter.nih.gov
Enhancing Sympathetic Outflow Control Following Spinal Cord Injury Using Targeted Plasticity TherapyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,419,630March 15, 2023February 29, 2028GANZER, PATRICK Dreporter.nih.gov
Mechanisms of Corticospinal Tract RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,415,004April 1, 2019March 31, 2024STEWARD, OSWALDreporter.nih.gov
A Blood Test for Mild Traumatic Brain Injury and Concussion in Children and Youth - Changing the Management ParadigmNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,412,102September 30, 2008May 31, 2025PAPA, LINDAreporter.nih.gov
The Function and Mechanisms of Voltage-Gated Proton Channel Hv1 in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,411,621May 15, 2020April 30, 2026WU, JUNFANGreporter.nih.gov
Optimizing respiratory plasticity with chronic cervical SCINIHNational Heart, Lung, and Blood Institute2021 to 2022$1,408,984April 4, 2019March 31, 2025MITCHELL, GORDON S.reporter.nih.gov
The Impact of Diffuse Mild Brain Injury on Clinical Outcomes in ChildrenNIHNational Institute of Neurological Disorders and Stroke2021$1,408,563July 1, 2016March 31, 2025MAYER, ANDREW ROBERTreporter.nih.gov
Novel role and mechanisms of histone deacetylases in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,407,028July 1, 2018June 30, 2025DIXON, C EDWARDreporter.nih.gov
Discovery of Biomarker Signatures Prognostic for Neuropathic Pain after Acute Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024$1,401,149September 1, 2019June 30, 2026HERGENROEDER, GEORGENE Wreporter.nih.gov
Influence of the College Football Athletes' Cumulative Head Impact Exposure (HIE) on the mTBI incidence and post-mTBI health outcomesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,390,766March 1, 2022February 28, 2027HAREZLAK, JAROSLAWreporter.nih.gov
Glycemic and Weight Loss Effects of Semaglutide in Subjects After Spinal Cord Injury and Type 2 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,384,859September 1, 2024May 31, 2028SALEHI, MARZIEHreporter.nih.gov
Response-contingent learning to modulate synaptic plasticity for spinal cord injuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$1,384,314September 1, 2025August 31, 2028SONG, SHANGreporter.nih.gov
Spinal Cord Stimulation to Improve Motor Function in People with Post-Stroke HemiplegiaNIHNational Institute of Neurological Disorders and Stroke2025$1,382,533September 8, 2022August 31, 2027CAPOGROSSO, MARCOreporter.nih.gov
Intraspinal circuits supporting synergy between the bladder and urethral sphincter in miceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,379,250July 1, 2021May 31, 2026YOSHIMURA, NAOKIreporter.nih.gov
Neurovascular Interactions: Mechanisms, Imaging, TherapeuticsNIHNational Institute of Neurological Disorders and Stroke2025$1,375,478September 1, 2025August 31, 2033AKASSOGLOU, KATERINAreporter.nih.gov
Spinal Neuromodulation to Promote Physiologic and Molecular Plasticity in theInjured Spinal CordNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,370,280September 20, 2023August 31, 2028HORNER, PHILIP Jreporter.nih.gov
Restoration of Postural Control After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,368,265July 1, 2011July 31, 2026DELIAGINA, TATIANA Greporter.nih.gov
Caveolin-1 contributes to the long-term function and structure of the neurovascular unit after juvenile concussionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,367,595August 1, 2021March 31, 2024OBENAUS, ANDREreporter.nih.gov
Circadian control of neuroinflammation after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,362,026April 1, 2023March 31, 2028GAUDET, ANDREW DAVIDreporter.nih.gov
Reprogramming Microglial Epigenetic Pathways to Promote Cognitive Recovery after Brain Trauma.NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,352,994April 1, 2019March 31, 2025FADEN, ALAN IRAreporter.nih.gov
Lymphatic Support of Neurogenesis and regenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,352,634December 1, 2022November 30, 2027HARRISON, MICHAELreporter.nih.gov
The trigeminal nociceptive-pain pathway in pediatric mTBI: peripheral and central contributions to photophobiaNIHNational Eye Institute2023 to 2025$1,352,579August 1, 2023June 30, 2028MOULTON, ERIC ALANreporter.nih.gov
Molecular genetic mechanisms of spontaneous spinal cord regenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,350,701July 15, 2016March 31, 2028GRANATO, MICHAELreporter.nih.gov
In-Vivo Monitoring of Therapeutic Drug Transport Across Biological BarriersNIHNational Institute of General Medical Sciences2021 to 2025$1,350,201September 1, 2021September 2, 2025ARROYO CURRAS, NETZAHUALCOYOTLreporter.nih.gov
Optical Dissection of Intracortical Circuits Supporting Motor Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,347,210June 15, 2019May 31, 2024HOLLIS, EDMUND Rreporter.nih.gov
Spinal circuits for sensorimotor integration and interlimb coordination during locomotionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,338,880September 21, 2020June 30, 2026DANNER, SIMON MICHAELreporter.nih.gov
Low-Cost High-Performance NIRS-SCOS Device for Non-Invasive Monitoring of Cerebral Blood Flow and Intracranial Pressure in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,334,987June 1, 2024May 31, 2029FRANCESCHINI, MARIA ANGELAreporter.nih.gov
Nanoparticle-mediated reduction of oxidative stress for the treatment of traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,323,263August 1, 2019July 31, 2025KIEVIT, FORREST Mreporter.nih.gov
The role of SOCE in microglia and secondary degeneration after SCINIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,321,908February 1, 2023December 31, 2027STIRLING, DAVID PAULreporter.nih.gov
Impact of intimate partner violence-related mild traumatic brain injuries on neural, cognitive, and psychological health of womenNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,317,906September 1, 2019July 31, 2025VALERA, EVE Mreporter.nih.gov
Mechanism of Inflammatory Related Brain Dysfunction after Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,312,047April 1, 2019March 31, 2025FADEN, ALAN IRAreporter.nih.gov
Long-term reliable neuroprosthetic control of a robotic arm and hand using electrocorticography.NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,311,848August 1, 2024July 31, 2029GANGULY, KARUNESHreporter.nih.gov
Homeostatic modeling of functional neuroimaging data in humans: a novel methodology to obtain brain maps of tissue pCO2, pO2 and pH in agingNIHNational Institute on Aging2024 to 2025$1,306,662August 15, 2024April 30, 2028MANGIA, SILVIAreporter.nih.gov
Development of Therapeutic Antibody for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021$1,292,737July 15, 2017March 31, 2023ZEIDEL, MARK L.reporter.nih.gov
3D Printed Scaffolds for Primate Spinal Cord Injury RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,290,219January 1, 2020December 31, 2023TUSZYNSKI, MARK H.reporter.nih.gov
Characterization of Physiological Changes Induced Through MEP Conditioning in People with SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,289,563December 1, 2019November 30, 2025THOMPSON, AIKOreporter.nih.gov
Central thalamic stimulation for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021$1,270,991September 30, 2015August 31, 2024SCHIFF, NICHOLAS Dreporter.nih.gov
Neuroimaging and Molecular Markers of AD and Neurodegenerative Disease after ConcussionNIHNational Institute on Aging2021 to 2023$1,270,086April 1, 2019January 31, 2026HAYES, JASMEET PANNUreporter.nih.gov
Mechanisms in Primary Nociceptors that Drive Ongoing Activity and Ongoing PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,269,063April 15, 2019March 31, 2025WALTERS, EDGAR T.reporter.nih.gov
KCC2 and Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,260,525March 15, 2019February 28, 2025HE, ZHIGANGreporter.nih.gov
AccelBand, a leg-worn transcutaneous neuromodulation device for treating neurogenic bowel dysfunction in individuals with spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,258,232September 15, 2022August 31, 2025PIKOV, VICTORreporter.nih.gov
Dopamine modulation for the treatment of chronic dysfunction due to traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,257,620May 15, 2019April 30, 2025VONDER HAAR, COLEreporter.nih.gov
Microbiota-targeted approaches to resolve dysbiosis-induced AD neuropathology following brain injury.NIHNational Institute on Aging2023 to 2024$1,254,408September 15, 2023August 31, 2025VILLAPOL, SONIAreporter.nih.gov
Defining the Role of Post-TBI Sleep Disruption in the Development of CTE and Alzheimer's Disease-Related NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2025$1,253,356September 20, 2022August 31, 2027PESKIND, ELAINE R.reporter.nih.gov
Role of Irg-1/itaconate in modulating secondary brain damage after traumatic brain injury in miceNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,249,975January 1, 2023December 31, 2027WANG, XIAOYINGreporter.nih.gov
SPIRIT Club CBI Pathway: A novel streaming platform for physical activity and wellness promotion for chronic brain injury survivorsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,244,908July 1, 2024December 31, 2026CINER, JARED PHILLIPreporter.nih.gov
A mechanistic clinical trial of omega-3 fatty acids to prevent subconcussive neural injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,232,442June 1, 2024May 31, 2029KAWATA, KEISUKEreporter.nih.gov
Methylomics of pediatric traumatic brain injury and neurobehavioral recoveryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,228,422May 15, 2024April 30, 2029TREBLE-BARNA, AMERYreporter.nih.gov
Human Schwann Cell-Derived Exosome Treatment for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,227,651August 1, 2023July 31, 2027DIETRICH, W DALTONreporter.nih.gov
Metabolic Mechanisms of Recovery in Mild TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,226,649September 1, 2024July 31, 2028FIRESTEIN, BONNIE Lreporter.nih.gov
Characterizing Sleep Disruption as a Post-Injury Immune StressorNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,208,508April 1, 2019March 31, 2024KOKIKO-COCHRAN, OLGA NICOLEreporter.nih.gov
Prediction of Shoulder Injury for Disease Prevention in Children and Adults with Spinal Cord Injury Using Advanced Biomechanical Modeling and Diagnostic ImagingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,191,928July 1, 2019March 31, 2025SLAVENS, BROOKE Areporter.nih.gov
Multiscale modeling and large-scale recordings of trauma-induced epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,190,537September 30, 2018July 31, 2024SEJNOWSKI, TERRENCE Jreporter.nih.gov
Preclinical characterization of a novel neuropeptide for inducing "on-demand" voidingNIHNational Institute of Neurological Disorders and Stroke2021$1,187,722February 1, 2019May 31, 2022BURGARD, EDWARDreporter.nih.gov
Acute neural injury and posttraumatic epilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,178,077June 14, 2024April 30, 2029BINDER, DEVIN Kreporter.nih.gov
Lesion and Activity Dependent Corticospinal Tract PlasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,177,584May 19, 2009May 31, 2025MARTIN, JOHN Hreporter.nih.gov
Brain Injury Treatment by Modulation of Hemodynamics with Blood Soluble Drag Reducing MoleculesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,176,334August 1, 2019May 31, 2024BRAGIN, DENIS E.reporter.nih.gov
Normobaric Oxygen Therapy for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,175,737August 3, 2024May 31, 2029FULLER, DAVID Dreporter.nih.gov
How do the neck muscles influence head acceleration during sport-associated impact events in high school athletes?NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,173,654August 28, 2018July 31, 2025ECKNER, JAMES TRAVISreporter.nih.gov
TBI leads to degeneration of afferent neuronal projectionsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,165,725March 15, 2023January 31, 2029FRIEDMAN, WILMA Jreporter.nih.gov
SCH: Robotic Caregiver to Comprehend, Assist, Relieve, and Evaluate for Patients with Alzheimer’s Disease (Robotic CARE for AD)NIHNational Institute on Aging2022 to 2025$1,151,897February 15, 2022January 31, 2027QI, HAIRONGreporter.nih.gov
Investigating Injury Tolerance and Mechanisms of Neonatal Brachial Plexus Palsy and Associated InjuriesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,149,306April 1, 2022March 31, 2027SINGH, ANITAreporter.nih.gov
Non-invasive infrared light therapy and medical device to treat spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,148,499August 15, 2024May 31, 2029HUETTEMANN, MAIKreporter.nih.gov
Translational Approaches to Mitigate Enhanced Alzheimer’s Disease Risk Following a Mild TBINIHNational Institute of Neurological Disorders and Stroke2021$1,147,500April 1, 2021February 29, 2024BACHSTETTER, ADAM Dreporter.nih.gov
Hyperbaric oxygen therapy mitigates respiratoryneuromuscular pathology after spinal cord injuryNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,143,750August 9, 2020July 31, 2025FULLER, DAVID Dreporter.nih.gov
Neuroimaging and Connectome Analysis as a Diagnostic and Prognostic Biomarker of SCI Induced Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,141,192December 26, 2023November 30, 2028ALIZADEH, MAHDIreporter.nih.gov
3D visualization and Investigation of Retinal Axon RegenerationNIHNational Eye Institute2021 to 2023$1,139,738April 1, 2021February 29, 2024PARK, KEVIN KYUNGreporter.nih.gov
Combinatorial Manipulation of Transcription Factors to Promote CNS RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,138,878July 15, 2013February 28, 2026BLACKMORE, MURRAY Greporter.nih.gov
Longitudinal Assessment of Post-concussion Driving in Young Adults (LAPDYA)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,132,197September 1, 2023May 31, 2028SCHMIDT, JULIANNE Dreporter.nih.gov
A nanomagnetic platform technology to characterize traumatic brain injury using brain derived extracellular vesiclesNIHNational Institute of Mental Health2021 to 2022$1,131,775September 19, 2018July 31, 2025ISSADORE, DAVID AARONreporter.nih.gov
Defining the mechanisms of MSC extracellular vesicle modulation of microglia metabolism and bioenergetics in traumatic brain injury recoveryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,131,196September 8, 2023June 30, 2029WEST, FRANKLIN Dreporter.nih.gov
Vagus nerve stimulation drives plasticity through inhibitory interneuronsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,125,037June 1, 2024April 30, 2029WELLE, CRISTIN Greporter.nih.gov
Protecting Endogenous Recovery from the "Infectious Insult" in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,121,721September 20, 2024August 31, 2029FILOUS, ANGELA Rreporter.nih.gov
Neuromodulatory rehabilitation for respiratory motor function in individuals with chronic spinal cord injuryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,119,616April 10, 2023March 31, 2028OVECHKIN, ALEXANDER VLADIMIROVICHreporter.nih.gov
Thalamic microglia drive cognitive impairment after cortical injuriesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,113,322June 18, 2024May 31, 2029KANO, SHINICHIreporter.nih.gov
Efficacy and mechanism of a community wellness promotion program for middle-aged adults living with long-term physical disabilityNIHNational Institute of Nursing Research2021 to 2022$1,113,187June 8, 2018March 31, 2024MOLTON, IVAN Rreporter.nih.gov
Intraspinal Microstimulation for Multi-modal RehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,113,032August 15, 2019February 28, 2027MCPHERSON, JACOB GRAVESreporter.nih.gov
Soluble TNFa in the development of autonomic dysreflexia after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,110,300April 15, 2018March 31, 2025TOM, VERONICA JEANreporter.nih.gov
Management of Blepharoptosis with Neodymium Magnet Systems: The Boston Blink-netic ProjectNIHNational Eye Institute2021 to 2022$1,105,200September 30, 2018May 31, 2024HOUSTON, KEVIN EDWARDreporter.nih.gov
Molecular imaging of brain injury and repair in NFL playersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,104,636January 1, 2018November 30, 2024COUGHLIN, JENNIFER MARIEreporter.nih.gov
Mechanisms of Functional Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,099,218March 1, 2019January 31, 2025BYRNE, ALEXANDRAreporter.nih.gov
Subcortical auditory processing in sports-related concussions and contact/collision sportsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,094,410March 1, 2018February 29, 2024KRAUS, NINAreporter.nih.gov
Training Program on Innovative Approaches to Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,092,376July 1, 2021June 30, 2026BAAS, PETER W.reporter.nih.gov
Lipid imaging in Traumatic Brain Injury by high resolution GCIB-secondary ion mass spectrometryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,091,238July 1, 2012June 30, 2023BAYIR, HÜLYAreporter.nih.gov
Molecular Mechanisms Regulating Inhibitory Circuitry in the Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,087,788July 1, 2013April 30, 2024KALTSCHMIDT, JULIA ANNAreporter.nih.gov
Spreading Depolarizations and Neuronal VulnerabilityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,084,348January 1, 2018February 28, 2030SHUTTLEWORTH, CLAUDE Wreporter.nih.gov
Multi-Modal Imaging of the Mechanisms Underlying Impaired Executive Attention After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,080,844December 1, 2017November 30, 2024KUCEYESKI, AMY FRANCESreporter.nih.gov
Lipid Biomarker Efflux from the Brain following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,080,171May 1, 2020March 31, 2025LAPLACA, MICHELLE Creporter.nih.gov
Neural Control of Muscle ActivityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,076,183September 30, 1978June 30, 2024PERLMUTTER, STEVE Ireporter.nih.gov
Mechanisms of metabolic adaptation after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,074,609February 15, 2019January 31, 2026SCAFIDI, SUSANNAreporter.nih.gov
Role of fatty acid oxidation after pediatric head injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,074,609March 1, 2019February 28, 2026SCAFIDI, SUSANNAreporter.nih.gov
Single stage surgical intervention for treatment of severe traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,068,513November 15, 2024February 28, 2027DETAMORE, MICHAEL S.reporter.nih.gov
The integrated stress response and oligodendrocyte survival after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,068,102June 15, 2018March 31, 2023HETMAN, MICHALreporter.nih.gov
Global analysis of the supraspinal connectome after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,067,149April 1, 2024December 31, 2028BLACKMORE, MURRAY Greporter.nih.gov
Microglial Function and Neurologic Outcome in Rat Pups after Experimental Traumatic Brain Injury: Effects of Timing and Duration of Docosahexaenoic Acid TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,064,374July 1, 2020April 30, 2026SCHOBER, MICHELLE ELENAreporter.nih.gov
The role of propriospinal neurons in the recovery of posture after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,054,492April 1, 2024March 31, 2029HECKMAN, CHARLESreporter.nih.gov
Retraining Neural Pathways to Improve Cognitive Skills after a Mild Traumatic Brain Injury (mTBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,054,265March 15, 2024April 23, 2024LAWTON, TERI Areporter.nih.gov
Oxidative Lipidomics in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,050,715May 1, 2025April 30, 2028BAYIR, HÜLYAreporter.nih.gov
Enhanced Bedside Microdialysis for TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,047,839August 15, 2018July 31, 2025MICHAEL, ADRIAN Creporter.nih.gov
Recovering amnestic memories from the repeat head impact brainNIHNational Institute of Neurological Disorders and Stroke2021$1,040,000June 1, 2021May 31, 2024BURNS, MARK Preporter.nih.gov
Spinal Cord Stimulation: A Novel Method to Restore Breathing in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,039,354April 1, 2018March 31, 2024DIMARCO, ANTHONY F.reporter.nih.gov
Targeting urinary tract dysfunctions after spinal cord injury with epidural stimulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,035,997September 15, 2023June 30, 2026HUBSCHER, CHARLES H.reporter.nih.gov
TBI Identification and Monitoring Through Retinal ScanningNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,035,000May 1, 2020March 31, 2026SHAKA, JUSTINreporter.nih.gov
Intrathecal pump delivery of neurotrophins for locomotor recovery after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,026,990April 1, 2020March 31, 2025LEMAY, MICHEL Areporter.nih.gov
Engineering astroglial bridges for axons across severe SCI lesionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,023,750August 1, 2014March 31, 2025SOFRONIEW, MICHAEL Vreporter.nih.gov
Technology development for closed-loop deep brain stimulation to treat refractory neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,022,290July 1, 2019June 30, 2024CHANG, EDWARDreporter.nih.gov
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,021,474January 15, 2021October 31, 2025ESOPENKO, CARRIE LYNNreporter.nih.gov
Mechanisms of electrical stimulation of a canonical motor microcircuitNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,020,975September 30, 2018August 31, 2024HECKMAN, CHARLESreporter.nih.gov
iPPSIS: implanted Passive Pressure Sensor Interrogated with (ultra)-SoundNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,019,458June 15, 2024March 31, 2028MYERS, DAVID RICHARDreporter.nih.gov
Investigation of Cognitive and Affective Deficits Post TBI Using Multimodal Flexible Neural ProbesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,018,381April 23, 2024March 31, 2029CUI, XINYAN TRACYreporter.nih.gov
RIT1-mediated Protection following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,017,998February 15, 2018January 31, 2025ANDRES, DOUGLAS ALLENreporter.nih.gov
Noninvasive Spinal Cord Perfusion Techniques with MRINIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,010,625December 1, 2018November 30, 2024BUDDE, MATTHEW Dreporter.nih.gov
Regulation of swallow and the effects of high cervical spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,010,625December 15, 2018November 30, 2024PITTS, TERESA Greporter.nih.gov
Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$1,006,075December 1, 2020November 30, 2025KOZIN, ELLIOTTreporter.nih.gov
Bioinformatics for post-traumatic stressNIHNational Institute of Mental Health2021 to 2022$1,003,992August 10, 2018May 31, 2024NIELSON, JESSICA LEIGHreporter.nih.gov
Pathophysiological remodeling of the enteric neuromuscular compartment in experimental spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$999,145March 15, 2019January 31, 2026HOLMES, GREGORY M.reporter.nih.gov
Pro-Survival Responses to Neurocellular StressNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$994,967December 15, 2023November 30, 2028HALPAIN, SHELLEY Lreporter.nih.gov
Patch-based deep scRNA-Seq to understand axon repair in the mammalian spinal cordNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$993,499July 15, 2024June 30, 2029ZHENG, BINHAIreporter.nih.gov
Targeting Non-Neuronal Mechanisms for Spinal Cord Injury RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$993,278April 15, 2019September 30, 2024TEDESCHI, ANDREAreporter.nih.gov
The Role of Corticospinal Neurons in the Recovery of Dexterous Forelimb Function After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$992,986May 5, 2024April 30, 2029HOLLIS, EDMUND Rreporter.nih.gov
Automatic Control of Standing Balance and Gait with Implanted NeuroprosthesesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$990,972September 21, 2000July 31, 2025TRIOLO, RONALD Jreporter.nih.gov
High-performance compact 3T MRI: Technical optimization for advanced brain imagingNIHNational Institute of Biomedical Imaging and Bioengineering2021$990,588September 18, 2017May 31, 2023BERNSTEIN, MATTHEW A.reporter.nih.gov
Post-trial Access, Clinical Care, Psychosocial Support, and Scientific Progress in Experimental Deep Brain Stimulation ResearchNIHNational Institute of Mental Health2023 to 2024$987,816August 18, 2023May 31, 2027LAZARO-MUNOZ, GABRIELreporter.nih.gov
Treatment of traumatic brain injury with vepoloxamerNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$987,657June 1, 2019May 31, 2025ZHANG, YANLUreporter.nih.gov
Analytical Validation of Tau and P-Tau as acute and subacute prognostic biomarkers for complicated mild TBINIHNational Institute of Neurological Disorders and Stroke2023 to 2024$982,050August 15, 2020July 31, 2026WANG, KEVIN KA WANGreporter.nih.gov
Cell-Specific Actions of IL-1 / IL-1R1 Signaling Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$981,676December 15, 2018November 30, 2024BACHSTETTER, ADAM Dreporter.nih.gov
Novel therapeutic approaches for traumatic brain injury induced cognitive deficitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$981,473December 1, 2019November 30, 2024SALVEMINI, DANIELAreporter.nih.gov
Designing Computer-Mediated Communication Supports to Improve Social Participation After Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$979,841August 6, 2012May 31, 2024DUFF, MELISSA Creporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Pittsburgh at PittsburghPittsburgh, PA36$49.4 million0$0
University of Maryland BaltimoreBaltimore, MD21$42 million0$0
Boston University Medical CampusBoston, MA22$40.8 million0$0
Ohio State UniversityColumbus, OH34$39.6 million0$0
University of California Los AngelesLos Angeles, CA17$37.3 million0$0
University of California, San DiegoLa Jolla, CA19$36.4 million0$0
University of Michigan at Ann ArborAnn Arbor, MI14$36 million0$0
Washington UniversitySaint Louis, MO24$35.2 million0$0
University of PennsylvaniaPhiladelphia, PA25$34.3 million0$0
University of WashingtonSeattle, WA24$32.5 million0$0
Massachusetts General HospitalBoston, MA22$27.4 million0$0
Yale UniversityNew Haven, CT11$27.2 million0$0
Drexel UniversityPhiladelphia, PA27$24.8 million0$0
University of UtahSalt Lake City, UT14$24.7 million0$0
University of KentuckyLexington, KY23$23.6 million0$0
Johns Hopkins UniversityBaltimore, MD19$23.5 million0$0
University of FloridaGainesville, FL21$22.4 million0$0
Case Western Reserve UniversityCleveland, OH18$22.1 million0$0
University of California, San FranciscoSan Francisco, CA19$21.9 million0$0
University of LouisvilleLouisville, KY18$21.7 million0$0
University of Miami School of MedicineCoral Gables, FL17$20.9 million0$0
University of MinnesotaMinneapolis, MN12$19.9 million0$0
Columbia University Health SciencesNew York, NY10$18.5 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX15$16.3 million0$0
University of Southern CaliforniaLos Angeles, CA10$16.1 million0$0
Northwestern University at ChicagoChicago, IL13$15.3 million0$0
Duke UniversityDurham, NC13$15.1 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA13$14.5 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY7$14.1 million0$0
Vanderbilt University Medical CenterNashville, TN8$13.7 million0$0
Virginia Commonwealth UniversityRichmond, VA9$13.4 million0$0
Emory UniversityAtlanta, GA15$13.3 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA10$12.5 million0$0
Oregon Health & Science UniversityPortland, OR9$12.5 million0$0
Ut Southwestern Medical CenterDallas, TX12$12.4 million0$0
Mayo Clinic RochesterRochester, MN9$12.2 million0$0
University of Alabama at BirminghamBirmingham, AL11$11.8 million0$0
University of RochesterRochester, NY7$11.6 million0$0
University of Colorado DenverAurora, CO9$11.3 million0$0
Salk Institute for Biological StudiesLa Jolla, CA4$11.1 million0$0
Rehabilitation Institute of Chicago D/b/a Shirley Ryan AbilitylabChicago, IL10$10.7 million0$0
Florida International UniversityMiami, FL2$10.6 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM3$10.6 million0$0
University of VirginiaCharlottesville, VA7$10.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY6$10.4 million0$0
Laureate Institute for Brain ResearchTulsa, OK1$10.3 million0$0
Augusta UniversityAugusta, GA7$9.8 million0$0
Albert Einstein College of MedicineBronx, NY2$9.6 million0$0
University of Vermont & ST Agric CollegeBurlington, VT3$9.2 million0$0
Seattle Children's HospitalSeattle, WA5$9.1 million0$0
Indiana University IndianapolisIndianapolis, IN10$9 million0$0
University of Colorado at BoulderBoulder, CO3$8.5 million0$0
Medical University of South CarolinaCharleston, SC5$8.4 million0$0
University of ArizonaTucson, AZ8$8.3 million0$0
California Institute of TechnologyPasadena, CA2$8 million0$0
Thomas Jefferson UniversityPhiladelphia, PA4$7.9 million0$0
Medical College of WisconsinMilwaukee, WI9$7.7 million0$0
University of California-IrvineIrvine, CA7$7.3 million0$0
University of Wisconsin-MilwaukeeMilwaukee, WI2$7.1 million0$0
University of California-RiversideRiverside, CA5$7.1 million0$0
Texas A&m University Health Science CTRCollege Station, TX7$7 million0$0
Stanford UniversityStanford, CA8$7 million0$0
Seattle Inst for Biomedical/clinical ResSeattle, WA3$6.9 million0$0
William Marsh Rice UniversityHouston, TX2$6.8 million0$0
Sri InternationalMenlo Park, CA1$6.6 million0$0
Washington State UniversityPullman, WA2$6.5 million0$0
Research Inst Nationwide Children's HospColumbus, OH5$6.5 million0$0
New York University School of MedicineNew York, NY4$6.4 million0$0
Methodist Hospital Research InstituteHouston, TX5$6.1 million0$0
Versapeutics INCSan Diego, CA4$6 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA4$5.6 million0$0
Indiana UniversityBloomington, IN3$5.4 million0$0
Boston Children's HospitalBoston, MA4$5.2 million0$0
Lovelace Biomedical Research InstituteAlbuquerque, NM3$5.1 million0$0
Brigham and Women's HospitalBoston, MA7$5.1 million0$0
University of Texas HLTH Science CenterSan Antonio, TX4$5.1 million0$0
University of CincinnatiCincinnati, OH6$4.9 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN1$4.7 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH3$4.7 million0$0
Eicosis, LLCDavis, CA1$4.6 million0$0
Rutgers University New BrunswickNew Brunswick, NJ8$4.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA4$4.4 million0$0
Texas A&M UniversityCollege Station, TX3$4.4 million0$0
Marquette UniversityMilwaukee, WI6$4.3 million0$0
Georgia Tech Research CorporationAtlanta, GA5$4.1 million0$0
University of Texas Med BR GalvestonGalveston, TX4$4.1 million0$0
George Washington UniversityWashington, DC4$4.1 million0$0
Winifred Masterson Burke Med Res InstWhite Plains, NY6$3.9 million0$0
University of Illinois at ChicagoChicago, IL3$3.8 million0$0
Baylor College of MedicineHouston, TX4$3.8 million0$0
University of Georgia Research Foundation IncAthens, GA6$3.7 million0$0
New Jersey Institute of TechnologyNewark, NJ3$3.7 million0$0
Wayne State UniversityDetroit, MI3$3.7 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA2$3.6 million0$0
ST. Joseph's Hospital and Medical CenterPhoenix, AZ3$3.5 million0$0
Spaulding Rehabilitation HospitalCharlestown, MA4$3.4 million0$0
Kessler Foundation, Inc.East Hanover, NJ2$3.3 million0$0
J. David Gladstone InstitutesSan Francisco, CA3$3.2 million0$0
University of Texas at DallasRichardson, TX3$3.1 million0$0
Biocircuit Technologies, Inc.Atlanta, GA1$3.1 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025483$275,231,0580$0
2024535$298,200,1700$0
2023557$301,832,0440$0
2022557$304,353,5680$0
2021554$284,854,4000$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 5 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 754 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 754 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 754 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 754 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 754 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 754 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 754 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 754 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 754 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 754 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 754 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 754 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 754 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 754 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 754 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 754 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.