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Data / Research funding / Traumatic Brain Injury (TBI)

Traumatic Brain Injury (TBI): 652 NIH awards ($932M) to 202 organizations

652 NIH awards ($932M) in the NIH spending category Traumatic Brain Injury (TBI), to 202 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 652 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$15,805,224July 1, 2018November 30, 2025BARSAN, WILLIAM Greporter.nih.gov
1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAHNIHNational Institute on Drug Abuse2021 to 2025$13,649,176September 30, 2015March 31, 2027YURGELUN-TODD, DEBORAH A.reporter.nih.gov
Endophenotypes of Persistent Post-Concussive Symptoms in Adolescents: CARE4KidsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$12,522,070September 8, 2021March 31, 2027GIZA, CHRISTOPHER Creporter.nih.gov
5/21 ABCD-USA Consortium: Research Project Site at UC San DiegoNIHNational Institute on Drug Abuse2021 to 2025$10,821,558September 30, 2015March 31, 2027TAPERT, SUSAN F.reporter.nih.gov
9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGANNIHNational Institute on Drug Abuse2021 to 2025$10,318,458September 30, 2015March 31, 2027HEITZEG, MARY Mreporter.nih.gov
15/21 ABCD-USA Consortium: Research Project Site at LIBRNIHNational Institute on Drug Abuse2021 to 2025$10,302,955April 15, 2020March 31, 2027PAULUS, MARTIN P.reporter.nih.gov
4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIUNIHNational Institute on Drug Abuse2021 to 2025$9,979,334September 30, 2015March 31, 2027GONZALEZ, RAULreporter.nih.gov
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLNIHNational Institute on Drug Abuse2021 to 2025$9,776,479April 15, 2020March 31, 2027MADDEN, PAMELA ANNreporter.nih.gov
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a TrialNIHNational Institute on Aging2021 to 2025$9,481,336February 15, 2021November 30, 2026HANLEY, DANIEL Freporter.nih.gov
2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMBNIHNational Institute on Drug Abuse2021 to 2025$9,449,174September 30, 2015March 31, 2027ERNST, THOMAS Mreporter.nih.gov
University of New Mexico (UNM) Center for Brain Recovery and RepairNIHNational Institute of General Medical Sciences2021 to 2024$9,061,444September 15, 2015June 30, 2026SHUTTLEWORTH, CLAUDE Wreporter.nih.gov
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,833,081April 15, 2022March 31, 2027GALANOPOULOU, ARISTEA Sreporter.nih.gov
7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALENIHNational Institute on Drug Abuse2021 to 2025$8,739,227September 30, 2015March 31, 2027BASKIN-SOMMERS, ARIELLE RYANreporter.nih.gov
19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVMNIHNational Institute on Drug Abuse2021 to 2025$8,669,646April 15, 2020March 31, 2027GARAVAN, HUGH P.reporter.nih.gov
3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTANIHNational Institute on Drug Abuse2021 to 2025$8,298,588September 30, 2015March 31, 2027LUCIANA, MONICAreporter.nih.gov
6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSUNIHNational Institute on Drug Abuse2021 to 2025$8,270,799September 30, 2015March 31, 2027NAGEL, BONNIE J.reporter.nih.gov
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderNIHNational Institute on Drug Abuse2021 to 2025$8,148,103April 15, 2020March 31, 2027BANICH, MARIE Treporter.nih.gov
20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCUNIHNational Institute on Drug Abuse2021 to 2025$7,897,207April 15, 2020March 31, 2027BJORK, JAMES Mreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,746,716September 15, 2021August 31, 2028BOGNER, JENNIFER Areporter.nih.gov
University of Maryland Claude D. Pepper Older Americans Independence Center (OAIC)NIHNational Institute on Aging2021 to 2025$6,970,364September 15, 2006June 30, 2027RYAN, ALICE S.reporter.nih.gov
18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDANIHNational Institute on Drug Abuse2021 to 2025$6,741,640April 15, 2020March 31, 2027NIXON, SARA JOreporter.nih.gov
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGHNIHNational Institute on Drug Abuse2021 to 2025$6,727,386September 30, 2015March 31, 2027CLARK, DUNCAN B.reporter.nih.gov
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRINIHNational Institute on Drug Abuse2021 to 2025$6,613,511September 30, 2015March 31, 2027BAKER, FIONA Creporter.nih.gov
17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLANIHNational Institute on Drug Abuse2021 to 2025$6,450,915April 15, 2020March 31, 2027DAPRETTO, MIRELLAreporter.nih.gov
Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project IINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$6,308,426August 15, 2024July 31, 2029ALOSCO, MICHAELreporter.nih.gov
Traumatic Brain Injury and Repetitive Head Impacts: Contributions to AD/ADRD and CTE Neuropathology and Resulting Clinical SyndromesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,142,337September 30, 2019July 31, 2025MCKEE, ANN C.reporter.nih.gov
11/21 ABCD-USA Consortium: Research Project Site at UWMNIHNational Institute on Drug Abuse2021 to 2025$5,941,105July 15, 2017March 31, 2027LISDAHL, KRISTA MAURINEreporter.nih.gov
13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSCNIHNational Institute on Drug Abuse2021 to 2025$5,745,020July 1, 2017March 31, 2027SQUEGLIA, LINDSAYreporter.nih.gov
Intracranial multimodal physiological monitoring in acute brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,648,369August 15, 2022July 31, 2025SPENCER, DENNIS Dreporter.nih.gov
16/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UNIVERSITY OF ROCHESTERNIHNational Institute on Drug Abuse2021 to 2025$5,419,981April 15, 2020March 31, 2027FOXE, JOHN Jreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$5,043,999September 15, 2021August 31, 2023BOGNER, JENNIFER Areporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2022$5,005,696September 1, 2022August 31, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Hyperbaric Oxygen Brain Injury Treatment (HOBIT) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,664,374September 30, 2017June 30, 2029ROCKSWOLD, GAYLAN Lreporter.nih.gov
Brain fluid clearance and misfolded protein dynamics following traumatic brain injuryNIHNational Institute on Aging2023 to 2025$4,618,282September 30, 2023June 30, 2029BUTLER, TRACY A.reporter.nih.gov
Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk FactorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,613,790December 15, 2015November 30, 2023STERN, ROBERT Areporter.nih.gov
An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCIDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,539,313September 22, 2023August 31, 2028VAN DER KOUWE, ANDRE JAN WILLEMreporter.nih.gov
Tools for Common Data Element Adoption in the Pan-Neurotrauma Data Commons (PANORAUMA)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,311,013September 1, 2021January 31, 2026FERGUSON, ADAM Rreporter.nih.gov
The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)NIHNational Institute of Neurological Disorders and Stroke2021$4,283,451May 8, 2020November 30, 2022TOGA, ARTHUR Wreporter.nih.gov
Consequences of Exposure to Repetitive Head Impacts Across the LifespanNIHNational Institute of Neurological Disorders and Stroke2025$4,269,339June 1, 2025May 31, 2027MCKEE, ANN C.reporter.nih.gov
Neuroimaging and clinical Endpoints With High-dimensional analysis Of Pathological Endophenotypes in TBI (NEW-HOPE-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$4,213,033August 15, 2024July 31, 2029KEENE, CHRISTOPHER DIRKreporter.nih.gov
Transdisciplinary Research Accelerating Neuropathology Studies and Facilitating Open Research Methods in TBI (TRANSFORM-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,951,871June 1, 2024April 30, 2029SMITH, DOUGLAS HAMILTONreporter.nih.gov
Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,917,121February 1, 2021January 31, 2027ALOSCO, MICHAELreporter.nih.gov
Minimally Invasive Cerebral Blood Flow and Oxygenation Monitoring for Intracranial HypertensionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,861,972September 20, 2022November 30, 2026FLOYD, THOMAS FREDERICKreporter.nih.gov
Defining the Role of Post-TBI Sleep Disruption in the Development of CTE and Alzheimer's Disease-Related NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2022$3,859,922September 20, 2022August 31, 2025PESKIND, ELAINE R.reporter.nih.gov
Language Processing in Context Following Traumatic Brain InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,792,881December 11, 2019May 31, 2030DUFF, MELISSA Creporter.nih.gov
Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)NIHNational Institute on Aging2021 to 2023$3,567,627March 15, 2019November 30, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Blood-based AD biomarkers profile in CAPCOG-TBI studyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,393,269September 1, 2023May 31, 2028DING, KANreporter.nih.gov
Brain Injury Outpatient Education and Care NavigationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,389,312August 15, 2021April 30, 2027RIVARA, FREDERICK P.reporter.nih.gov
Defining short RNA therapeutics that combat TDP-43 proteinopathy connected to AD and ADRDs.NIHNational Institute on Aging2025$3,360,074September 15, 2025August 31, 2029SHORTER, JAMESreporter.nih.gov
Contributions of astrocyte RelA signaling in aging-related neurodegenerative sequelae following TBINIHNational Institute on Aging2021 to 2025$3,313,377January 15, 2021December 31, 2026MORGANTI, JOSHreporter.nih.gov
A longitudinal study of traumatic brain injury in a high-risk populationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,150,729August 4, 2022May 31, 2027KIEHL, KENT Areporter.nih.gov
Longitudinal MRI Investigation of Traumatic Microvascular InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,116,729February 15, 2022January 31, 2027WARE, JEFFREY Breporter.nih.gov
Modeling the role of age at traumatic brain injury in the development of Alzheimer's Disease and related dementiasNIHNational Institute of Neurological Disorders and Stroke2024$3,109,079August 1, 2024July 31, 2027OBENAUS, ANDREreporter.nih.gov
Exosome biology in Alzheimer's disease and concussionNIHNational Institute on Aging2021 to 2025$3,108,983August 15, 2021April 30, 2027GRANHOLM-BENTLEY, ANN-CHARLOTTE ESTHERreporter.nih.gov
Developing Gyrencephalic Models of TBI-Induced ADRD NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2024$3,102,638August 15, 2024July 31, 2027JOHNSON, VICTORIA ELEANORreporter.nih.gov
Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,082,121March 15, 2020February 28, 2027DIAZ-ARRASTIA, RAMONreporter.nih.gov
The glymphatic system at the crossroad of integrative health approaches inchronic painNIHNational Center for Complementary & Integrative Health2021 to 2025$3,067,927August 1, 2021May 31, 2026NEDERGAARD, MAIKENreporter.nih.gov
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathiesNIHNational Institute on Aging2022 to 2025$3,053,656June 1, 2022February 28, 2027LIAO, DEZHIreporter.nih.gov
Strategy to Potentiate Rehabilitation after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,022,533December 1, 2020November 30, 2026HARRIS, NEILreporter.nih.gov
Pediatric Severe Traumatic Brain Injury in Latin America – A Randomized Trial Comparing Two Management ProtocolsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,020,262August 1, 2021July 31, 2027CHESNUT, RANDALL Mreporter.nih.gov
Analytical characterization and validation of blood-biomarkers for monitoring TBI evolutionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,965,270August 10, 2024July 31, 2028PUCCIO, AVA M.reporter.nih.gov
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,919,684April 1, 2021March 31, 2026CULLEN, DANIEL KACYreporter.nih.gov
Functional Mechanism of Neural Control in Post-Concussion Convergence InsufficiencyNIHNational Eye Institute2021 to 2025$2,883,808April 1, 2014August 31, 2026ALVAREZ, TARA LYNNreporter.nih.gov
A youth-specific helmet for preventing traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023$2,864,855September 30, 2020August 31, 2025AVERY, GORDONreporter.nih.gov
Poly-omic predictors of symptom duration and recovery for adolescent concussionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,846,441January 1, 2020December 31, 2026HICKS, STEVEN DANIELreporter.nih.gov
A Translational Evaluation of Sur1-Trpm4 Imaging Endophenotypes and Genetics to Direct Precision Medicine for Cerebral Edema After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,799,271May 5, 2021April 30, 2027JHA, RUCHIRA MENKAreporter.nih.gov
The Importance of Abnormal Inflammasome Activation as a Risk Factor between Traumatic Brain Injury and Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,797,800September 20, 2021August 31, 2026DIETRICH, W DALTONreporter.nih.gov
Subconcussive neurodegenerative progression in adolescent athletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,789,923December 15, 2020November 30, 2026KAWATA, KEISUKEreporter.nih.gov
Recovery among Older Adults Following Head InjuryNIHNational Institute on Aging2022 to 2025$2,752,989July 1, 2022March 31, 2027ALBRECHT, JENNIFER S.reporter.nih.gov
Mitigating neuroinflammation and enhancing neuronal integrity in Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$2,738,640September 30, 2022June 30, 2027MA, JIANJIEreporter.nih.gov
3D Models of the Blood-Brain Barrier for Studying Trauma-Induced Cerebral and Systemic InjuriesNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,735,039September 3, 2020August 31, 2025ZHENG, YINGreporter.nih.gov
Modulating Exercise Dosage to Improve Concussion Rehabilitation: A Randomized Clinical TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,688,941May 15, 2022March 31, 2027HOWELL, DAVID R.reporter.nih.gov
Structural characterization of tau conformational heterogeneity in Down syndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,686,309August 1, 2025July 31, 2026SOUTHWORTH, DANIEL RYLANDreporter.nih.gov
Amyloid-mediated cognitive dysfunction in bacterial pneumonia after TBINIHNational Institute on Aging2025$2,663,195September 15, 2025August 31, 2029WAGENER, BRANT Mreporter.nih.gov
identifying Concussed Adolescents at Risk for Emotional dysregulation 2 (iCARE2)NIHNational Institute of Mental Health2021 to 2025$2,660,976December 19, 2017May 31, 2029VERSACE, AMELIAreporter.nih.gov
Enhancing the function of hippocampal neurons after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,654,614June 1, 2021March 31, 2027DASH, PRAMOD Kreporter.nih.gov
Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization InitiativeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,639,985September 30, 2020May 31, 2027HILLARY, FRANK GERARDreporter.nih.gov
Divergent age-dependent peripheral innate immune response following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,619,872July 1, 2021June 30, 2027THEUS, MICHELLE LEEreporter.nih.gov
Mitochondrial Uncoupling Prodrug as a Translational Therapy for TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,607,985March 15, 2020July 31, 2026SULLIVAN, PATRICK Greporter.nih.gov
Neurovascular unit dysfunction in Down syndrome revealed by TBINIHNational Institute of Neurological Disorders and Stroke2022$2,601,812September 7, 2022August 31, 2025HUANG, MINGXIAreporter.nih.gov
Prefrontal Anatomic Pathways in Executive ControlNIHNational Institute of Mental Health2021 to 2024$2,592,328July 1, 1987January 31, 2026BARBAS, HELENreporter.nih.gov
Development of a novel peptide therapeutic for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,571,585February 3, 2025March 31, 2026MANN, AMANreporter.nih.gov
Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,544,711March 15, 2020February 28, 2025DUFF, MELISSA Creporter.nih.gov
Diffusion MRI Model Parameter Estimation to Study Brain Microstructure as it Relates to Cognitive Status in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,534,685August 15, 2021July 31, 2025LUI, YVONNE Wreporter.nih.gov
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,525,196August 1, 2020July 31, 2026GILMORE, EMILYreporter.nih.gov
Personalized Profiles of Pathology in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,515,544January 1, 2022November 30, 2026DENNIS, EMILY LARSENreporter.nih.gov
The Contribution of Repetitive Head Impacts and Social Determinants of Health to Alzheimer's Disease and Related Dementia in Older Adult Black MenNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,514,590August 15, 2023July 31, 2028TURNER, ROBERT W.reporter.nih.gov
The inflammatory mechanisms underlying olfactory dysfunction in prognosis of TBI progression to dementiaNIHNational Institute on Aging2022 to 2025$2,508,327June 15, 2022March 31, 2027WU, JUNFANGreporter.nih.gov
Longitudinal Assessment of Driving After Mild TBI in TeensNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,507,174September 11, 2020July 31, 2026YANG, JINGZHEN GINGERreporter.nih.gov
Traumatic Brain Injury Anti-Seizure Prophylaxis in the Medicare ProgramNIHNational Institute on Aging2023 to 2025$2,504,051September 15, 2023May 31, 2028MOURA, LIDIA MARIA VERAS ROCHA DEreporter.nih.gov
Robust and Rapid 3D High-Resolution Cranial bone imaging for pediatric patients using MRINIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,488,491December 1, 2021November 30, 2026AN, HONGYUreporter.nih.gov
Exploiting sex-dependent brain injury response for nanoparticle therapeuticsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,482,558January 1, 2021November 30, 2025STABENFELDT, SARAH Ereporter.nih.gov
Mobile Subthreshold Exercise Program for Concussion (M-STEP)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,482,057September 8, 2020August 31, 2025CHRISMAN, SARA P.D.reporter.nih.gov
Bidirectional Brain-Gut interactions, chronic neuroinflammation and neurodegeneration after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,480,051August 15, 2022July 31, 2027FADEN, ALAN IRAreporter.nih.gov
Novel mechanisms suppressing the pro-resolving phenotype of peripheral innate immunity following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,473,913June 1, 2021March 31, 2027THEUS, MICHELLE LEEreporter.nih.gov
The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,466,010April 1, 2024August 31, 2026SCHWULST, STEVEN Jreporter.nih.gov
Dysregulation of autophagy-lysosomal function links TBI to late-onset neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,458,515April 1, 2020March 31, 2026LIPINSKI, MARTA Mreporter.nih.gov
EValuation Of Longitudinal outcomes in mild TBI Active-Duty Military and VEterans 10-YearNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,448,807April 1, 2015April 30, 2026MACDONALD, CHRISTINE Lreporter.nih.gov
Trauma, the gut, and the brain: the gut microbiota-microglia axis in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,439,002August 1, 2022July 31, 2027SCHWULST, STEVEN Jreporter.nih.gov
von Willebrand Factor in Traumatic Brain Injury and Associated CoagulopathyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,120April 1, 2020March 31, 2025DONG, JING-FEIreporter.nih.gov
The Contribution of Age-Related Tauopathies to Alzheimer's DiseaseNIHNational Institute on Aging2023$2,430,703September 30, 2018August 31, 2026MCKEE, ANN C.reporter.nih.gov
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,423,278January 15, 2021November 30, 2026ESOPENKO, CARRIE LYNNreporter.nih.gov
Novel tools for in vitro electrophysiology and neurotrauma modelingNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,414,021August 17, 2020January 31, 2026FINAN, JOHN Dreporter.nih.gov
Building and implementing a TBI prognostic model featuring real-time analysis of brain CT imagesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,387,866June 1, 2022May 31, 2027DUNN, TIMOTHY WILLIAMreporter.nih.gov
A randomized controlled trial of an innovative in-home rehabilitation program for persons with TBI and their families: Home-based Occupational-therapy and Management of the Environment (HOME for Us)NIHNational Institute of Nursing Research2021 to 2024$2,379,845September 15, 2020June 30, 2026MORIARTY, HELENE JOYreporter.nih.gov
Mechanisms of Circadian and Synaptic Dysfunction After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2022$2,366,184June 1, 2022May 31, 2025WHALEN, MICHAEL Jreporter.nih.gov
Traumatic Axonopathy in the CNS as Wallerian degenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,365,581January 1, 2021November 30, 2026KOLIATSOS, VASSILIS Ereporter.nih.gov
Detect: A novel device to assess how HIV affects neurocognitive decline and postural instability in older adults at risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$2,349,852February 15, 2019November 30, 2024MOORE, RAEANNE CRISTINEreporter.nih.gov
Assessing Diffusion MRI Metrics for Detecting Changes of Synaptic Density in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$2,313,017September 15, 2023May 31, 2028WU, YU-CHIENreporter.nih.gov
Pulsed laser therapy in an asymptomatic head injury-accelerated Alzheimer's modelNIHNational Institute of Neurological Disorders and Stroke2024$2,309,898September 17, 2024August 31, 2027ZHANG, QUANGUANGreporter.nih.gov
Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric SymptomsNIHNational Institute of Neurological Disorders and Stroke2021$2,309,451September 15, 2021August 31, 2024ALOSCO, MICHAELreporter.nih.gov
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021$2,302,768April 1, 2021March 31, 2024ZHAO, ZHENreporter.nih.gov
Reprogramming proinflammatory microglia by restoring mitochondrial functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,300,527July 1, 2020June 30, 2025POLSTER, BRIAN Mreporter.nih.gov
Contribution of Innate Immune Receptors to Neurological Dysfunction After Traumatic Brain Injury: Mechanisms and Therapeutic ImplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,291,943April 1, 2021March 31, 2027SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
Optimizing Collaborative Care for Youth with Persistent Post-Concussive SymptomsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,275,364February 3, 2017April 30, 2028MC CARTY, CAROLYN Areporter.nih.gov
Precision Medicine Approach: Using genomic information to guide TBI treatmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,251,700January 15, 2020December 31, 2025GOMEZ-PINILLA, FERNANDOreporter.nih.gov
Improving Outcomes for Care Partners of Persons with Traumatic Brain InjuryNIHNational Institute of Nursing Research2021 to 2024$2,247,328September 27, 2012November 30, 2025CARLOZZI, NOELLE E.reporter.nih.gov
Stabilizing the Tripartite Synaptic Complex Following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,237,377February 1, 2017December 31, 2027LIEBL, DANIEL JONreporter.nih.gov
MRI Measurement of the Mechanical Vulnerability of the BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,235,019September 15, 2019July 31, 2025BAYLY, PHILIP Vreporter.nih.gov
Heading and Soccer: Understanding Cognitive Risks, Benefits, and the Potential Mediating Role of White MatterNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,220,345August 1, 2022July 31, 2027LIPTON, MICHAEL LAWRENCEreporter.nih.gov
Spatiotemporal Molecular Substrates of TBI at Single Cell ResolutionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,218,963July 1, 2020March 31, 2026YANG, XIAreporter.nih.gov
Neuroprotective B Cell Immunotherapy for Contusion Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,197,906May 1, 2021February 28, 2027SIRBULESCU, RUXANDRA Freporter.nih.gov
Development of Molecular Probe Inhibitors of Pathogenic, Cytosolic Cathespin B in Traumatic Brain Injury and Alzheimers Disease NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,197,366August 1, 2019June 30, 2025HOOK, VIVIAN Y. Hreporter.nih.gov
Assessing the effects of peripheral immune activation on the NVU following TBI using a vascularized and perfused human blood/BBB modelNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,181,059September 15, 2021August 31, 2026AGALLIU, DRITANreporter.nih.gov
Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolismNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,169,572September 1, 2020August 31, 2025PARK, JAE MOreporter.nih.gov
Chronic and Evolving Inflammation after Traumatic Brain Injury: Microglial Priming and Neuropsychiatric ComplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,169,210April 1, 2021March 31, 2026GODBOUT, JONATHAN Preporter.nih.gov
Rewiring the Injured Brain with GABA ProgenitorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,163,757February 15, 2016March 31, 2027HUNT, ROBERT Freporter.nih.gov
Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2022$2,152,606August 1, 2016August 31, 2025RANUM, LAURA P.Wreporter.nih.gov
Retinal eye-tracking as a prognostic tool for traumatic brain injury and concussionNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,150,115July 16, 2016August 31, 2025SHEEHY, CHRISTY KATHLEENreporter.nih.gov
Transforming Research And Clinical Knowledge in Geriatric Traumatic Brain Injury (TRACK-GERI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,145,667September 1, 2019May 31, 2025MANLEY, GEOFFREY Treporter.nih.gov
Implementation Fidelity and Benefits of the Critical Care Pediatric Guideline Adherence and Outcomes Program in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,137,509January 1, 2019December 31, 2024VAVILALA, MONICA Sreporter.nih.gov
Vestibular System Function Following Blast ExposureNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,126,775March 1, 2021February 28, 2027DICKMAN, J DAVIDreporter.nih.gov
A Randomized Controlled Trial of BETTER, A Transitional Care Intervention, for Patients with Traumatic Brain Injury and Their FamiliesNIHNational Institute of Nursing Research2023 to 2025$2,125,541May 19, 2023February 28, 2028OYESANYA, TOLU O.reporter.nih.gov
SNSPD-DCS at 1064 nm for non-invasive monitoring of cerebral perfusion and intracranial pressure in the ICUNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$2,109,015September 1, 2023August 31, 2028FRANCESCHINI, MARIA ANGELAreporter.nih.gov
Neurobehavioral consequences of Mild Traumatic Brain Injury and addiction risk: a cotwin-control studyNIHNational Institute on Drug Abuse2023 to 2025$2,093,963September 30, 2023July 31, 2028ANOKHIN, ANDREY P.reporter.nih.gov
Exploring Mechanisms Underlying SCF+G-CSF-Enhanced Recovery in ChronicTBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,093,761April 1, 2021March 31, 2027ZHAO, LI-RUreporter.nih.gov
A physiologically relevant pre-clinical drug screening platform for Alzheimer's Disease and Traumatic Brain Injury with integrated stretchable microelectrodesNIHNational Institute on Aging2022 to 2025$2,090,923September 30, 2022November 30, 2026GRAUDEJUS, OLIVERreporter.nih.gov
Analytical Validation of Portable Devices for Detection of Traumatic Brain Injury BiomarkersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,066,291August 1, 2021April 30, 2027WU, NIANQIANGreporter.nih.gov
Optimizing Environmental Enrichment to Model Preclinical NeurorehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,054,372May 15, 2014June 30, 2026KLINE, ANTHONY E.reporter.nih.gov
The Contribution of Age-Related Taupahtoies to Alzheimer's Disease-SupplementNIHNational Institute on Aging2021 to 2022$2,048,437September 30, 2018August 31, 2023MCKEE, ANN C.reporter.nih.gov
Cell Specific RIPK3 Signaling After Traumatic Brain Injury in MiceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,035,353April 1, 2021December 31, 2026WHALEN, MICHAEL Jreporter.nih.gov
Neurobehavioral, cognitive, and mechanistic effects of intranasally administered neural stem cells and environmental enrichment after cortical impact injury in ratsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,032,869September 1, 2021August 31, 2025KLINE, ANTHONY E.reporter.nih.gov
Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical InjuriesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,031,527July 1, 2021June 30, 2027CHEN, HAN-CHIAO ISAACreporter.nih.gov
Deep Brain Stimulation of the Cerebellar Dentate Nucleus to Enhance Chronic, Post-Traumatic Brain Injury RehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,019,158July 1, 2020June 30, 2026BAKER, KENNETH Breporter.nih.gov
Nano-Pulsed Optoacoustic Neuromodulation for Reducing Traumatic Brain Injury-Driven Neuropathology and Improving Cognitive OutcomeNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,007,911June 1, 2022May 31, 2027MICCI, MARIA-ADELAIDEreporter.nih.gov
MicroRNA Therapeutics for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,987,816February 15, 2020January 31, 2026LIU, DAZHI JEFFreporter.nih.gov
Immunometabolic regulation after CNS injuryNIHNational Institute of Neurological Disorders and Stroke2023$1,975,262September 21, 2023August 31, 2026DHANDAPANI, KRISHNAN M.reporter.nih.gov
Role of Peripheral Inflammation in TBI PathobiologyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,973,761February 1, 2022January 31, 2027DASH, PRAMOD Kreporter.nih.gov
Optimized Sodium MR Imaging at Clinical Field Strength to Study in vivo Sodium Signal in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,962,114April 25, 2023March 31, 2028LUI, YVONNE Wreporter.nih.gov
Multi-modal machine learning detection and tracking of traumatic brain injury neurodegeneration and its differentiation from Alzheimer's diseaseNIHNational Institute on Aging2022 to 2023$1,958,406September 30, 2018July 31, 2025LUKIC, ANA Sreporter.nih.gov
Impact of TBI and Cognitive Decline on Alzheimer's Disease Brain-Derived Exosome CargoNIHNational Institute on Aging2023$1,948,168June 1, 2023May 31, 2026RISSMAN, ROBERTreporter.nih.gov
Driving after Concussion: Examination of the Adolescent Brain and BehaviorsNIHNational Institute of Nursing Research2021 to 2024$1,943,796April 3, 2020January 31, 2026MCDONALD, CATHERINE CLAIREreporter.nih.gov
Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related DementiasNIHNational Institute of Neurological Disorders and Stroke2023$1,940,666June 1, 2023May 31, 2025ALOSCO, MICHAELreporter.nih.gov
Mechanisms and Therapeutic Strategies for Post-traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,934,562July 15, 2020June 30, 2025PORRECA, FRANKreporter.nih.gov
Noninvasive transcranial detection of intracranial hemorrhage using a tri-coil handheld portable eddy current damping imaging deviceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,924,473January 15, 2021December 31, 2025ZADA, GABRIELreporter.nih.gov
Assessing the effects of peripheral immune activation on the NVU following TBI using avascularized and perfused human blood/BBB model.NIHNational Heart, Lung, and Blood Institute2021 to 2022$1,914,338September 15, 2021August 31, 2023AGALLIU, DRITANreporter.nih.gov
Comprehensive Quantitative Profiling of Cellular Alterations Caused by InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,911,936July 1, 2019March 31, 2026ROYSAM, BADRINATHreporter.nih.gov
Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST StudyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,905,236June 1, 2023May 31, 2028KRISHNAMOORTHY, VIJAYreporter.nih.gov
The molecular intersection of tau, TBI, and PERKNIHNational Institute on Aging2021 to 2025$1,898,625September 30, 2021May 31, 2026ABISAMBRA, JOSE FRANCISCOreporter.nih.gov
Comprehensive White-matter Microstructure-informed Analytical Methods to Elucidate Neurobiological Mechanisms of Sports-related Concussion (SRC)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,877,939April 15, 2020August 31, 2025WU, YU-CHIENreporter.nih.gov
Axonal Varicosity Dynamics in Central Neuron Mechanosensation and InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,876,746June 15, 2016March 31, 2027GU, CHENreporter.nih.gov
MRI Markers of Feedback Timing during Learning in Individuals with TBI with and without Clinical DepressionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,849,868April 1, 2021January 31, 2027DOBRYAKOVA, EKATERINAreporter.nih.gov
Novel Carbon Nanozyme Mechanisms for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,833,893September 1, 2015March 31, 2026KENT, THOMASreporter.nih.gov
Defining the remote effects of cortical spreading depolarizations on hippocampus after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,824,305February 15, 2023January 31, 2028NGWENYA, LAURA BENJAMINreporter.nih.gov
Central Thalamic Deep Brain Stimulation to Regulate Arousal and CognitionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,821,751April 1, 2020March 31, 2025BAKER, JONATHAN Lreporter.nih.gov
Pediatric Mild Traumatic Brain Injury and the ABCD Study: A Prospective Behavioral, Psychiatric, Neurocognitive, Imaging, and Genetic InvestigationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,820,333June 15, 2022April 30, 2027MAX, JEFFREY EDWINreporter.nih.gov
Biomarkers in the Hyperbaric Oxygen in Brain Injury Treatment TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,818,192September 15, 2020August 31, 2027KORLEY, FREDERICK KOFIreporter.nih.gov
Minimally Invasive Cerebral Blood Flow and Oxygenation Monitoring for Intracranial HypertensionNIHNational Institute of Neurological Disorders and Stroke2022$1,814,829September 20, 2022March 31, 2024FLOYD, THOMAS FREDERICKreporter.nih.gov
Role of Sleep Disruption after mTBI as a Driver of Chronic Post-traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,798,407July 1, 2023June 30, 2028ILIFF, JEFFREY Jreporter.nih.gov
A Risk Stratification Model for Health and Academic Outcomes in Children with Concussion Based on Novel Symptom Trajectory TypologiesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,797,265March 1, 2023February 29, 2028REUTER-RICE, KARINreporter.nih.gov
Connecting Alzheimer's Disease to Traumatic Synaptic NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,775,841May 1, 2022March 31, 2028KUMMER, TERRANCE Treporter.nih.gov
Lasting Impacts: Dynamic, Fully Natural Bioprinted 3D Human Neurovascular Biomimetic Model to Study Traumatic Brain Injury PathophysiologyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,766,629September 15, 2021December 31, 2026MOYA, MONICA LIZETreporter.nih.gov
Role of Neuronal p38 MAPK After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,766,593September 30, 2020June 30, 2026WOOD, LEVI BENJAMINreporter.nih.gov
Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic PlasticityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,761,885December 1, 2021November 30, 2026PAZ, JEANNE Treporter.nih.gov
Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass SpectrometryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,756,092July 1, 2012July 31, 2028BAYIR, HÜLYAreporter.nih.gov
Anti-microbial platelet-like-particles to treat internal bleeding and augment subsequent healingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,752,994April 1, 2023March 31, 2027BROWN, ASHLEY CARSONreporter.nih.gov
Mesenchymal Stem Cell Derived Extracellular Vesicles for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,721,728June 15, 2018June 30, 2030SHETTY, ASHOK Kreporter.nih.gov
Development of Novel sgp130-Fc Bioconjugates for TBINIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,721,185February 15, 2023August 31, 2027HASKINS, WILLIAM Ereporter.nih.gov
Human Brain Interferometers for Better Blood Flow MonitoringNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,720,177April 13, 2021December 31, 2024SRINIVASAN, VIVEK JAYreporter.nih.gov
Effects of Head Impact Exposure During Contact Sport on Middle School and High School AthletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,718,817April 1, 2019June 30, 2025WANG, YANGreporter.nih.gov
Synaptic Vesicular Alterations after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,715,310August 15, 2022June 30, 2027CARLSON, SHAUNreporter.nih.gov
Rapid saliva test for diagnosis of mTBI and prognosis of Persistent Post-conccussion Symptoms (PPCS) in children and adultsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,698,783September 17, 2021August 31, 2024SOUTHERN, SARKA OLIVERAreporter.nih.gov
Neuronal IL-1R1 Signaling in Mild Closed Head InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,696,702July 1, 2022May 31, 2027BACHSTETTER, ADAM Dreporter.nih.gov
Axonal Pathology and TBI-Related Neurodegeneration (TReND)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,695,531April 1, 2016December 31, 2027SMITH, DOUGLAS HAMILTONreporter.nih.gov
Immune-modifying nanoparticles for the treatment of traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,685,137August 1, 2020April 30, 2025KESSLER, JOHN Areporter.nih.gov
INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRINGNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,682,280January 15, 2022November 30, 2026COHEN, AKIVA Sreporter.nih.gov
Development of a Colorimetric Sensor for Detection of Cerebrospinal Fluid LeaksNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,680,880January 2, 2023December 31, 2025HU, MINreporter.nih.gov
Identifying Potential Therapeutic Targets for Abusive Head TraumaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,679,245September 1, 2020August 31, 2025COSTINE-BARTELL, BETH Areporter.nih.gov
Solid-state nanopores and silicon nanomembranes for ultrasensitive protein biomarker detectionNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,678,043June 15, 2021March 31, 2026MCGRATH, JAMES Lreporter.nih.gov
Poly-Matching Causal Inference for Assessing Multiple Acute Medical Managements of Pediatric Traumatic Brain InjuriesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,673,547February 1, 2023January 31, 2028XIANG, HENRYreporter.nih.gov
Improving Patient Classification and Outcome Measurement in Traumatic Brain Injury (TBI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,666,852May 15, 2019March 31, 2026NELSON, LINDSAYreporter.nih.gov
Traumatic brain injury and aging: targeting the cholinergic system for deficits in sustained attention and executive functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,665,105August 1, 2024April 30, 2026BONDI, CORINA OANAreporter.nih.gov
Impact of microbiota-derived metabolites on traumatic brain injury-related neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,660,221January 1, 2023December 31, 2027SIMON, DENNIS WILLIAMreporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2025$1,638,533September 1, 2022August 31, 2027DAMS-O'CONNOR, KRISTENreporter.nih.gov
Hypertension, Blood Pressure Targets, and Alzheimer’s Disease and Dementia Risk and Disparities among Nationally Representative US VeteransNIHNational Institute on Aging2024 to 2025$1,629,636September 30, 2024June 30, 2029YAFFE, KRISTINEreporter.nih.gov
The Role of ApoE in Injury-Induced NeurogenesisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,627,788January 1, 2017June 30, 2027KERNIE, STEVEN GERARDreporter.nih.gov
Microglial process convergence following brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,627,616August 1, 2023July 31, 2027LAFRENAYE, AUDREY Dreporter.nih.gov
Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric SymptomsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,626,188September 15, 2021August 31, 2027ALOSCO, MICHAELreporter.nih.gov
Longitudinal Sub-thalamic Structure and Functional Alterations in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,619,153July 15, 2018May 31, 2025ZHUO, JIACHENreporter.nih.gov
Dopaminergic Mechanisms Underlying Behavioral Deficits Following Mild TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,616,918April 1, 2020February 28, 2026RAGHUPATHI, RAMESHreporter.nih.gov
The Therapeutic Potential of Cold Stored Platelets in Regulating Vascular Instability in TraumaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,615,000August 5, 2020June 30, 2025PATI, SHIBANIreporter.nih.gov
Gravida traumatic brain injury (TBI) impacts neurodevelopment of the offspringNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,608,657September 1, 2023May 31, 2026LIFSHITZ, JONATHANreporter.nih.gov
MRE elastography-based detection of impaired skull-brain decoupling after repetitive subconcussive sports impactNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,605,477September 15, 2019April 30, 2030YIN, ZIYINGreporter.nih.gov
Mild traumatic brain injury alters interneuron structure and functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,597,977September 1, 2011March 31, 2029JACOBS, KIMBERLE MAEreporter.nih.gov
The role of monocyte and microglia interaction in the evolution of traumatic brain injury-induced neurodegenerationNIHNational Institute of General Medical Sciences2021 to 2023$1,593,117September 1, 2019July 31, 2025SCHWULST, STEVEN Jreporter.nih.gov
Single stage surgical intervention for treatment of severe traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,588,284March 1, 2022June 30, 2024DETAMORE, MICHAEL S.reporter.nih.gov
Pilot Clinical Study to Assess Safety and Efficacy of External Ventricular Drainage with Cerebrospinal Fluid Water Removal Osmotherapy for Traumatic Brain Injury-Induced Cerebral EdemaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,570,119June 15, 2022January 31, 2026HOFMEISTER, JOEreporter.nih.gov
NOX2 drives microglia-dependent neurodegeneration after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,565,910August 1, 2022July 31, 2027STOICA, BOGDAN ADRIANreporter.nih.gov
In vivo MRI Measures of Brain Metabolism in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,551,605May 1, 2022April 30, 2027TU, TSANG-WEIreporter.nih.gov
Minocycline Plus N-Acetylcysteine Improves Brain Structure and Function After Experimental Brain Injury with Clinically Useful Time WindowsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,539,997February 1, 2019November 30, 2024BERGOLD, PETER Jreporter.nih.gov
Mechanisms of Chronic Progressive Axon Degeneration Following TBINIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,525,713August 15, 2022June 30, 2027SMITH, DOUGLAS HAMILTONreporter.nih.gov
Influence of thalamic IL-33 signaling in aging-associated exacerbation of cognitive impairment after brain injury via microglial dysfunction and tau pathologyNIHNational Institute on Aging2022 to 2024$1,522,144September 15, 2022August 31, 2025KANO, SHINICHIreporter.nih.gov
Epigenetic Age and Patient Outcomes after Severe Traumatic Brain InjuryNIHNational Institute on Aging2024 to 2025$1,522,029August 15, 2024April 30, 2029CONLEY, YVETTE Preporter.nih.gov
Preclinical Efficacy and Safety Evaluation of Oral AST-004 for Moderate Traumatic Brain Injury (TBI)NIHNational Institute of Neurological Disorders and Stroke2025$1,499,886June 12, 2025May 31, 2027LISTON, THEODORE Ereporter.nih.gov
Injury-Induced Alterations in Limbic Functional CircuityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,496,917April 1, 2003April 30, 2024COHEN, AKIVA Sreporter.nih.gov
Network Dysfunction and Neuromodulation following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,494,401April 1, 2017January 31, 2028WOLF, JOHN ALLENreporter.nih.gov
Mechanisms and Therapeutic Targeting of Chronic Neuroinflammation in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,489,949March 1, 2022February 28, 2027BRANN, DARRELL Wreporter.nih.gov
Dynamic temporal regulation of astrocyte coupling to shape neuronal activity during acquired epilepsy developmentNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,478,759May 15, 2022February 28, 2027ROBEL, STEFANIEreporter.nih.gov
Role of ASC in TBI-Mediated Systemic Inflammation.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,476,248December 1, 2019November 30, 2025KEANE, ROBERT Wreporter.nih.gov
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,466,564April 1, 2021March 31, 2026ZHAO, ZHENreporter.nih.gov
Subtle Motor Functioning and Functional Connectivity in Youth Medically Cleared after Mild TBINIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,456,488February 13, 2018January 31, 2025SUSKAUER, STACY JENNIFER MARCUSreporter.nih.gov
Timing Of Exercise In Concussed Rat AthletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,449,648March 1, 2019February 28, 2025PRINS, MAYUMI LYNNreporter.nih.gov
Mechanisms of type I interferon neuropathology following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,442,235September 19, 2023July 31, 2028NEWELL, ELIZABETHreporter.nih.gov
Therapeutic Targeting of Monoacylglycerol Lipase After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,436,743August 1, 2020April 30, 2026VAIBHAV, KUMARreporter.nih.gov
Can [18F]3F4AP Detect Brain Demyelination? Evaluation of Novel PET Tracer in Nonhuman Primates and HumansNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,426,088December 15, 2019November 30, 2025BRUGAROLAS, PEDROreporter.nih.gov
Cerebral Mechanisms of Vulnerability Following Female Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,420,105August 1, 2020April 30, 2026GRECO, TIFFANYreporter.nih.gov
A Blood Test for Mild Traumatic Brain Injury and Concussion in Children and Youth - Changing the Management ParadigmNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,412,102September 30, 2008May 31, 2025PAPA, LINDAreporter.nih.gov
The Impact of Diffuse Mild Brain Injury on Clinical Outcomes in ChildrenNIHNational Institute of Neurological Disorders and Stroke2021$1,408,563July 1, 2016March 31, 2025MAYER, ANDREW ROBERTreporter.nih.gov
Novel role and mechanisms of histone deacetylases in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,407,028July 1, 2018June 30, 2025DIXON, C EDWARDreporter.nih.gov
Influence of the College Football Athletes' Cumulative Head Impact Exposure (HIE) on the mTBI incidence and post-mTBI health outcomesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,390,766March 1, 2022February 28, 2027HAREZLAK, JAROSLAWreporter.nih.gov
Caveolin-1 contributes to the long-term function and structure of the neurovascular unit after juvenile concussionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,367,595August 1, 2021March 31, 2024OBENAUS, ANDREreporter.nih.gov
Reprogramming Microglial Epigenetic Pathways to Promote Cognitive Recovery after Brain Trauma.NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,352,994April 1, 2019March 31, 2025FADEN, ALAN IRAreporter.nih.gov
Lymphatic Support of Neurogenesis and regenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,352,634December 1, 2022November 30, 2027HARRISON, MICHAELreporter.nih.gov
The trigeminal nociceptive-pain pathway in pediatric mTBI: peripheral and central contributions to photophobiaNIHNational Eye Institute2023 to 2025$1,352,579August 1, 2023June 30, 2028MOULTON, ERIC ALANreporter.nih.gov
Low-Cost High-Performance NIRS-SCOS Device for Non-Invasive Monitoring of Cerebral Blood Flow and Intracranial Pressure in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,334,987June 1, 2024May 31, 2029FRANCESCHINI, MARIA ANGELAreporter.nih.gov
Nanoparticle-mediated reduction of oxidative stress for the treatment of traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,323,263August 1, 2019July 31, 2025KIEVIT, FORREST Mreporter.nih.gov
Impact of intimate partner violence-related mild traumatic brain injuries on neural, cognitive, and psychological health of womenNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,317,906September 1, 2019July 31, 2025VALERA, EVE Mreporter.nih.gov
Development of Therapeutic Antibody for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021$1,292,737July 15, 2017March 31, 2023ZEIDEL, MARK L.reporter.nih.gov
Central thalamic stimulation for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021$1,270,991September 30, 2015August 31, 2024SCHIFF, NICHOLAS Dreporter.nih.gov
Neuroimaging and Molecular Markers of AD and Neurodegenerative Disease after ConcussionNIHNational Institute on Aging2021 to 2023$1,270,086April 1, 2019January 31, 2026HAYES, JASMEET PANNUreporter.nih.gov
Dopamine modulation for the treatment of chronic dysfunction due to traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,257,620May 15, 2019April 30, 2025VONDER HAAR, COLEreporter.nih.gov
Microbiota-targeted approaches to resolve dysbiosis-induced AD neuropathology following brain injury.NIHNational Institute on Aging2023 to 2024$1,254,408September 15, 2023August 31, 2025VILLAPOL, SONIAreporter.nih.gov
Defining the Role of Post-TBI Sleep Disruption in the Development of CTE and Alzheimer's Disease-Related NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2025$1,253,356September 20, 2022August 31, 2027PESKIND, ELAINE R.reporter.nih.gov
Role of Irg-1/itaconate in modulating secondary brain damage after traumatic brain injury in miceNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,249,975January 1, 2023December 31, 2027WANG, XIAOYINGreporter.nih.gov
SPIRIT Club CBI Pathway: A novel streaming platform for physical activity and wellness promotion for chronic brain injury survivorsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,244,908July 1, 2024December 31, 2026CINER, JARED PHILLIPreporter.nih.gov
A mechanistic clinical trial of omega-3 fatty acids to prevent subconcussive neural injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,232,442June 1, 2024May 31, 2029KAWATA, KEISUKEreporter.nih.gov
Methylomics of pediatric traumatic brain injury and neurobehavioral recoveryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,228,422May 15, 2024April 30, 2029TREBLE-BARNA, AMERYreporter.nih.gov
Human Schwann Cell-Derived Exosome Treatment for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,227,651August 1, 2023July 31, 2027DIETRICH, W DALTONreporter.nih.gov
Metabolic Mechanisms of Recovery in Mild TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,226,649September 1, 2024July 31, 2028FIRESTEIN, BONNIE Lreporter.nih.gov
Characterizing Sleep Disruption as a Post-Injury Immune StressorNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,208,508April 1, 2019March 31, 2024KOKIKO-COCHRAN, OLGA NICOLEreporter.nih.gov
Multiscale modeling and large-scale recordings of trauma-induced epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,190,537September 30, 2018July 31, 2024SEJNOWSKI, TERRENCE Jreporter.nih.gov
Acute neural injury and posttraumatic epilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,178,077June 14, 2024April 30, 2029BINDER, DEVIN Kreporter.nih.gov
Brain Injury Treatment by Modulation of Hemodynamics with Blood Soluble Drag Reducing MoleculesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,176,334August 1, 2019May 31, 2024BRAGIN, DENIS E.reporter.nih.gov
How do the neck muscles influence head acceleration during sport-associated impact events in high school athletes?NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,173,654August 28, 2018July 31, 2025ECKNER, JAMES TRAVISreporter.nih.gov
TBI leads to degeneration of afferent neuronal projectionsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,165,725March 15, 2023January 31, 2029FRIEDMAN, WILMA Jreporter.nih.gov
Translational Approaches to Mitigate Enhanced Alzheimer’s Disease Risk Following a Mild TBINIHNational Institute of Neurological Disorders and Stroke2021$1,147,500April 1, 2021February 29, 2024BACHSTETTER, ADAM Dreporter.nih.gov
Longitudinal Assessment of Post-concussion Driving in Young Adults (LAPDYA)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,132,197September 1, 2023May 31, 2028SCHMIDT, JULIANNE Dreporter.nih.gov
A nanomagnetic platform technology to characterize traumatic brain injury using brain derived extracellular vesiclesNIHNational Institute of Mental Health2021 to 2022$1,131,775September 19, 2018July 31, 2025ISSADORE, DAVID AARONreporter.nih.gov
Defining the mechanisms of MSC extracellular vesicle modulation of microglia metabolism and bioenergetics in traumatic brain injury recoveryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,131,196September 8, 2023June 30, 2029WEST, FRANKLIN Dreporter.nih.gov
Thalamic microglia drive cognitive impairment after cortical injuriesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,113,322June 18, 2024May 31, 2029KANO, SHINICHIreporter.nih.gov
Management of Blepharoptosis with Neodymium Magnet Systems: The Boston Blink-netic ProjectNIHNational Eye Institute2021 to 2022$1,105,200September 30, 2018May 31, 2024HOUSTON, KEVIN EDWARDreporter.nih.gov
Molecular imaging of brain injury and repair in NFL playersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,104,636January 1, 2018November 30, 2024COUGHLIN, JENNIFER MARIEreporter.nih.gov
Subcortical auditory processing in sports-related concussions and contact/collision sportsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,094,410March 1, 2018February 29, 2024KRAUS, NINAreporter.nih.gov
Lipid imaging in Traumatic Brain Injury by high resolution GCIB-secondary ion mass spectrometryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,091,238July 1, 2012June 30, 2023BAYIR, HÜLYAreporter.nih.gov
Multi-Modal Imaging of the Mechanisms Underlying Impaired Executive Attention After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,080,844December 1, 2017November 30, 2024KUCEYESKI, AMY FRANCESreporter.nih.gov
Lipid Biomarker Efflux from the Brain following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,080,171May 1, 2020March 31, 2025LAPLACA, MICHELLE Creporter.nih.gov
Mechanisms of metabolic adaptation after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,074,609February 15, 2019January 31, 2026SCAFIDI, SUSANNAreporter.nih.gov
Role of fatty acid oxidation after pediatric head injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,074,609March 1, 2019February 28, 2026SCAFIDI, SUSANNAreporter.nih.gov
Single stage surgical intervention for treatment of severe traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,068,513November 15, 2024February 28, 2027DETAMORE, MICHAEL S.reporter.nih.gov
Microglial Function and Neurologic Outcome in Rat Pups after Experimental Traumatic Brain Injury: Effects of Timing and Duration of Docosahexaenoic Acid TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,064,374July 1, 2020April 30, 2026SCHOBER, MICHELLE ELENAreporter.nih.gov
Retraining Neural Pathways to Improve Cognitive Skills after a Mild Traumatic Brain Injury (mTBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,054,265March 15, 2024April 23, 2024LAWTON, TERI Areporter.nih.gov
Oxidative Lipidomics in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,050,715May 1, 2025April 30, 2028BAYIR, HÜLYAreporter.nih.gov
Enhanced Bedside Microdialysis for TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,047,839August 15, 2018July 31, 2025MICHAEL, ADRIAN Creporter.nih.gov
Recovering amnestic memories from the repeat head impact brainNIHNational Institute of Neurological Disorders and Stroke2021$1,040,000June 1, 2021May 31, 2024BURNS, MARK Preporter.nih.gov
TBI Identification and Monitoring Through Retinal ScanningNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,035,000May 1, 2020March 31, 2026SHAKA, JUSTINreporter.nih.gov
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,021,474January 15, 2021October 31, 2025ESOPENKO, CARRIE LYNNreporter.nih.gov
Investigation of Cognitive and Affective Deficits Post TBI Using Multimodal Flexible Neural ProbesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,018,381April 23, 2024March 31, 2029CUI, XINYAN TRACYreporter.nih.gov
RIT1-mediated Protection following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,017,998February 15, 2018January 31, 2025ANDRES, DOUGLAS ALLENreporter.nih.gov
Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$1,006,075December 1, 2020November 30, 2025KOZIN, ELLIOTTreporter.nih.gov
Bioinformatics for post-traumatic stressNIHNational Institute of Mental Health2021 to 2022$1,003,992August 10, 2018May 31, 2024NIELSON, JESSICA LEIGHreporter.nih.gov
Pro-Survival Responses to Neurocellular StressNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$994,967December 15, 2023November 30, 2028HALPAIN, SHELLEY Lreporter.nih.gov
Post-trial Access, Clinical Care, Psychosocial Support, and Scientific Progress in Experimental Deep Brain Stimulation ResearchNIHNational Institute of Mental Health2023 to 2024$987,816August 18, 2023May 31, 2027LAZARO-MUNOZ, GABRIELreporter.nih.gov
Treatment of traumatic brain injury with vepoloxamerNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$987,657June 1, 2019May 31, 2025ZHANG, YANLUreporter.nih.gov
Analytical Validation of Tau and P-Tau as acute and subacute prognostic biomarkers for complicated mild TBINIHNational Institute of Neurological Disorders and Stroke2023 to 2024$982,050August 15, 2020July 31, 2026WANG, KEVIN KA WANGreporter.nih.gov
Cell-Specific Actions of IL-1 / IL-1R1 Signaling Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$981,676December 15, 2018November 30, 2024BACHSTETTER, ADAM Dreporter.nih.gov
Novel therapeutic approaches for traumatic brain injury induced cognitive deficitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$981,473December 1, 2019November 30, 2024SALVEMINI, DANIELAreporter.nih.gov
Designing Computer-Mediated Communication Supports to Improve Social Participation After Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$979,841August 6, 2012May 31, 2024DUFF, MELISSA Creporter.nih.gov
K01 Menstrual Phase, Sexual Dysfunction, mTBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$974,443February 1, 2022August 31, 2026ANTO-OCRAH, MARTINAreporter.nih.gov
Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related DementiasNIHNational Institute of Neurological Disorders and Stroke2025$972,457June 1, 2023May 31, 2028ALOSCO, MICHAELreporter.nih.gov
VRC: Engineered extracellular vesicles for mild TBI-induced retinal injuryNIHNational Eye Institute2022 to 2024$967,616September 1, 2022May 31, 2026ROTH, STEVENreporter.nih.gov
Concussion and Driving Skills in the Young DriverNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$966,168July 15, 2019May 31, 2024RIVARA, FREDERICK P.reporter.nih.gov
Mitochondria: controllers of trauma-induced secondary neurodegeneration onsetNIHNational Eye Institute2024 to 2025$957,950July 1, 2024June 30, 2029REX, TONIA Sreporter.nih.gov
Investigating the role of gut-derived extracellular vesicles in PTSD following TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$948,280September 5, 2024August 31, 2029LIU, XIANSHUANGreporter.nih.gov
A Novel Platelet-Inspired Nanotechnology to Restore Hemostasis in Patients on Antiplatelet AgentsNIHNational Heart, Lung, and Blood Institute2025$944,676July 15, 2025June 30, 2027SEKHON, UJJAL DIDAR SINGHreporter.nih.gov
Predictive Accuracy of Acute Astroglial Compromise Biomarkers after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$942,747April 1, 2018August 31, 2024HARRIS, NEILreporter.nih.gov
The role of cytomegalovirus in the physiological and clinical effects of concussionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$939,462January 17, 2024November 30, 2027MEIER, TIMOTHY B.reporter.nih.gov
The Role of Sex Dimorphism in Post-TBI Bacterial PneumoniaNIHNational Institute of General Medical Sciences2021 to 2022$928,637September 21, 2018August 31, 2025WAGENER, BRANT Mreporter.nih.gov
Investigation of Cerebral Hemodynamics and Oxygenation Relationships Under Sedation in Children: ICHOR USCNIHNational Heart, Lung, and Blood Institute2021 to 2025$926,608September 10, 2021August 31, 2026BORZAGE, MATTHEWreporter.nih.gov
Targeting CNS Neuroinflammation in Traumatic Brain Injury by Nasal Anti-CD3NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$922,920April 1, 2022March 31, 2027IZZY, SAEFreporter.nih.gov
Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization InitiativeNIHNational Institute of Neurological Disorders and Stroke2021$921,538September 30, 2020February 28, 2023HILLARY, FRANK GERARDreporter.nih.gov
Research training and mentorship to strengthen brain health across the lifespan in Uganda.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$912,780September 15, 2020June 30, 2026KADDUMUKASA, MARKreporter.nih.gov
Neutrophil extracellular traps and associated pathogenesis in TBI: a novel peptide therapeutic strategy.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$885,500March 6, 2024June 19, 2025MUNEER, MOHAMMED ABDULreporter.nih.gov
Establishing Mechanisms Between Traumatic Brain Injury and Dementia Using Epidemiology, Clinical Studies, Blood-Based Biomarkers, and Neuroimaging BiomarkersNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$883,830May 1, 2022April 30, 2027SCHNEIDER, ANDREA LAUREN CHRISTMANreporter.nih.gov
Translational Outcomes Project: Visualizing Syndromic Information and Outcomes for Neurotrauma (TOP-VISION)NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$882,892April 1, 2018April 30, 2025FERGUSON, ADAM Rreporter.nih.gov
Objective Translational Multi-domain Early Concussion AssessmentNIHNational Institute of Neurological Disorders and Stroke2021$871,488July 1, 2018January 31, 2024MARGULIES, SUSAN SHEPSreporter.nih.gov
Risk Stratification Using Physiologic Markers and Mobile Health-Facilitated Specialist Management to Improve Outcomes in Pediatric Concussion PatientsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$862,332August 1, 2022July 31, 2027CORWIN, DANIELreporter.nih.gov
Caregiver Wellness after Traumatic Brain Injury (CG-WELL): An Intervention Designed to Promote Well-being in Caregivers of Acute Moderate to Severe Traumatic Brain InjuriesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$855,878May 1, 2021April 30, 2026KREITZER, NATALIEreporter.nih.gov
Sympathetic Activation and Cerebrovascular Pressure Reactivity after Traumatic Brain Injury (TBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$845,523July 15, 2023July 31, 2025PINTO, SHANTI MARIEreporter.nih.gov
Digital Neurodegenerative Pathology After Repetitive Head ImpactsNIHNational Institute of Neurological Disorders and Stroke2025$843,248May 7, 2025April 30, 2030MEZ, JESSE BENJAMINreporter.nih.gov
Satellite Microglia: Role in Maladaptive Network Remodeling after TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$834,988December 15, 2023November 30, 2028NOLAN, AMBER Lreporter.nih.gov
Cranial Osteopathic Manipulative Medicine Enhances Brain Fluid Flow Alleviating NeuroinflammationNIHNational Center for Complementary & Integrative Health2024 to 2025$832,545September 17, 2024June 30, 2029BROLINSON, PER GUNNARreporter.nih.gov
Trigeminovascular sensitization in post-traumatic headache: electrophysiologic and blood biomarkers in youthNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$828,731July 1, 2022May 31, 2027PATTERSON GENTILE, CARLYN ANNEreporter.nih.gov
Spectral ERG Analysis of Hypersensitivity to Light in Traumatic Brain InjuryNIHNational Eye Institute2021 to 2022$824,340April 1, 2020January 31, 2024TYLER, CHRISTOPHER Wreporter.nih.gov
The Impact of Diffuse Mild Brain Injury on Clinical Outcomes in ChildrenNIHNational Institute of Neurological Disorders and Stroke2025$821,974July 1, 2016January 31, 2030MAYER, ANDREW ROBERTreporter.nih.gov
AcSDKP as a novel treatment for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$819,219May 1, 2024February 28, 2029XIONG, YEreporter.nih.gov
Hyperbaric Oxygen Brain Injury Treatment (HOBIT) Trial - SDMC SDC SupplementNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$818,292July 1, 2022June 30, 2023MARTIN, RENEE HEBERTreporter.nih.gov
Characterization of the spatial and temporal response to tau in chronic traumatic encephalopathyNIHNational Institute on Aging2025$817,484December 1, 2024November 30, 2029CHERRY, JONATHAN Dreporter.nih.gov
Altered Central Multisensory Processing in Post-concussion Vestibular DysfunctionNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$814,163January 1, 2022December 31, 2023ALLEN, JASON WILLIAMreporter.nih.gov
Contribution of adult neurogenesis to epileptogenesis and recovery after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$812,923June 1, 2018May 31, 2025SMITH, BRET Nreporter.nih.gov
No REST for 5-HT Neurons Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$810,000September 3, 2024August 1, 2029ROBSON, MATTHEWreporter.nih.gov
Sex differences in neuroimmune function and developmental vulnerability to early life traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$801,494February 1, 2023January 31, 2029LENZ, KATHRYN M.reporter.nih.gov
Photophobia and Pupillary Autonomic Dysfunction as Biomarkers of Post-Traumatic HeadacheNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$795,587April 15, 2020September 30, 2025CORTEZ, MELISSAreporter.nih.gov
Oxidation of K+ channels mediates an amyloidogenic pathway common to Alzheimer's disease and TBINIHNational Institute on Aging2021 to 2022$795,000February 1, 2019November 30, 2022SESTI, FEDERICOreporter.nih.gov
Mechanisms by which CD74 Contributes to Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$788,141September 1, 2019August 31, 2025NEWELL ROGERS, M. KARENreporter.nih.gov
Oxidative Lipidomics in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$787,708July 1, 2008April 30, 2023BAYIR, HÜLYAreporter.nih.gov
Tau-independent effects of high frequency head impact on cognition and neurobehaviorNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$777,500July 1, 2018June 30, 2025BURNS, MARK Preporter.nih.gov
Endocannabinoids in Neurodegenerative DiseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$774,165June 15, 2012April 30, 2023CHEN, CHUreporter.nih.gov
Traumatic brain injury and Alzheimer's diseaseNIHNational Institute on Aging2021 to 2022$773,750June 21, 2019February 28, 2025CHEN, CHUreporter.nih.gov
Understanding the effect of post-concussive sleep disruption on glymphatic function in collegiate athletesNIHNational Heart, Lung, and Blood Institute2025$772,420April 4, 2025January 31, 2030PIANTINO, JUAN ANDRESreporter.nih.gov
The dynamic balance between neuronal volume and chloride handling in network excitability after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$768,750July 15, 2022May 31, 2024POKAM, PUNAM ADHIKreporter.nih.gov
Mechanisms of Circadian and Synaptic Dysfunction After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2025$765,679June 1, 2022May 31, 2027WHALEN, MICHAEL Jreporter.nih.gov
Pericyte Mechanisms in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$761,262June 15, 2018March 31, 2024LO, ENG H.reporter.nih.gov
Evaluating Huddles as a Novel Approach to Improving Concussion SafetyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$758,428May 5, 2025April 30, 2030KROSHUS-HAVRIL, EMILY GRACEreporter.nih.gov
Concussion and Attention-Deficit/Hyperactivity Disorder: Investigating the relationship between cognitive outcome, prescription stimulants, and functional MRI biomarkers in the ABCD study.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$758,064April 1, 2022March 31, 2027KAY, BENJAMIN PAULreporter.nih.gov
3D Models of the Blood-Brain Barrier for Studying Trauma-Induced Cerebral and Systemic InjuriesNIHNational Heart, Lung, and Blood Institute2021$757,760September 3, 2020August 31, 2022ZHENG, YINGreporter.nih.gov
EEG and MRI Biomarkers to Predict Post-traumatic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$757,377July 1, 2020June 30, 2025KIM, JENNIFER Areporter.nih.gov
Reversal of Immunoparalysis Following Traumatic Brain Injury and Systemic Hemorrhage in a Juvenile Rat ModelNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$750,540April 15, 2022March 31, 2027SRIBNICK, ERIC ANTHONYreporter.nih.gov
Sensor-Like LC-MS Platform for Rapid Online Monitoring of Metabolites in Biological SystemsNIHNational Institute of General Medical Sciences2024 to 2025$750,000September 15, 2024June 30, 2029GRINIAS, JAMES Preporter.nih.gov
Hyperfibrinogenemia and sphingolipid-mediated cerebrovascular permeability and memory impairment during TBINIHNational Institute of Neurological Disorders and Stroke2023$749,987August 15, 2023July 31, 2025LOMINADZE, DAVIDreporter.nih.gov
Mechanisms of neurodegeneration by a fibrinogen-containing protein complex during traumatic brain injuryNIHNational Heart, Lung, and Blood Institute2021 to 2022$747,500May 1, 2019April 30, 2025LOMINADZE, DAVIDreporter.nih.gov
Neutrophil Activation after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$747,232December 15, 2018November 30, 2024DHANDAPANI, KRISHNAN M.reporter.nih.gov
The dynamic balance between neuronal volume and chloride handling in network excitability after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$745,908July 15, 2022June 30, 2027POKAM, PUNAM ADHIKreporter.nih.gov
Validating an Administrative Claims Based Case Definition for Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$744,510September 7, 2021August 31, 2027KUMAR, RAJ GOPALANreporter.nih.gov
Heading and Soccer: understanding cognitive risks, benefits, and the potential mediating role of white matterNIHNational Institute of Neurological Disorders and Stroke2022$743,911August 1, 2022May 31, 2023LIPTON, MICHAEL LAWRENCEreporter.nih.gov
Mechanisms of Injury-induced Senescence and Immune-sequelae in Chronic TBINIHNational Institute of Neurological Disorders and Stroke2022 to 2024$739,527September 1, 2022August 31, 2025RITZEL, RODNEYreporter.nih.gov
Neurovascular unit dysfunction in Down syndrome revealed by TBINIHNational Institute of Neurological Disorders and Stroke2025$738,140September 7, 2022August 31, 2027HUANG, MINGXIAreporter.nih.gov
MUSICA - MUsic and Speech Induced Cerebral ActivationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$728,352June 1, 2022May 31, 2027ALKHACHROUM, AYHAMreporter.nih.gov
Translational Approaches to Mitigate Enhanced Alzheimer’s Disease Risk Following a Mild TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$726,750April 1, 2021February 28, 2027BACHSTETTER, ADAM Dreporter.nih.gov
Make Play Safe: Intervention to Increase Concussion Recognition and Reporting in Youth SoccerNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$715,357August 7, 2025July 31, 2030YANG, JINGZHEN GINGERreporter.nih.gov
Inflammasome activation and lymphatic dysfunction in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$706,562September 15, 2018July 31, 2023LUKENS, JOHN Rreporter.nih.gov
Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2025$705,919August 1, 2016August 31, 2027RANUM, LAURA P.Wreporter.nih.gov
Network Pharmacology for Epilepsy PreventionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$700,003September 22, 2021August 31, 2024KLEIN, PAVELreporter.nih.gov
The role of neuroactive kynurenine metabolites in the chronic sequelae of concussion and contact sport exposureNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$698,489December 1, 2017November 30, 2023MEIER, TIMOTHY B.reporter.nih.gov
Recovering amnestic memories from the repeat head impact brainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$684,000June 1, 2021May 31, 2027BURNS, MARK Preporter.nih.gov
Cilia Biomarker Kit Development for Brain Injury Diagnosis and Prognosis.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$683,624August 29, 2024July 31, 2026RAMCHANDRAN, RAMANIreporter.nih.gov
Cerebral Substrate Support After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$682,500September 30, 2018June 30, 2024PRINS, MAYUMI LYNNreporter.nih.gov
Neural Stem Cell Extracellular Vesicle Treatment for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$679,411June 1, 2022May 31, 2025STICE, STEVEN Lreporter.nih.gov
A Culturally-Adapted, Trauma-Informed Cognitive Rehabilitation Intervention for Asylum-Seekers and Refugees with Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$675,540December 1, 2022November 30, 2027SAADI, ALTAFreporter.nih.gov
Electrochemical assessment of behaviorally relevant circuit function after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$671,562December 15, 2017November 30, 2023THOMAS, THERESA CURRIERreporter.nih.gov
Automatic Quantification and Labeling of Cerebral Microbleeds, Oxygen Saturation and Sources of Abnormal SusceptibilityNIHNational Heart, Lung, and Blood Institute2021$667,050August 1, 2019January 31, 2022HAACKE, EWART MARKreporter.nih.gov
The effects of cumulative concussion, repetitive head impacts, and comorbid cardiovascular risk factors on MRI metrics of pathological aging and neurobehavioral functioning across the lifespanNIHNational Institute on Aging2021 to 2025$660,855August 1, 2021July 31, 2026BRETT, BENJAMIN Lreporter.nih.gov
Altered Central Multisensory Processing in Post-concussion Vestibular DysfunctionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$660,795January 1, 2022December 31, 2026ALLEN, JASON WILLIAMreporter.nih.gov
Atypical astrocytes in the aging cortexNIHNational Institute on Aging2022 to 2023$659,998February 1, 2022January 31, 2025DULLA, CHRIS Greporter.nih.gov
A link between sleep-wake disturbances and enlarged perivascular spaces in youth with traumatic brain injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$659,880March 15, 2020February 28, 2025PIANTINO, JUAN ANDRESreporter.nih.gov
COACH: COmmunities Aligned to reduce Concussion and Head impact exposure in youth footballNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$659,287January 1, 2025November 30, 2029URBAN, JILLIAN ELIZABETHreporter.nih.gov
Exosome-Based Therapeutics in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$658,438February 1, 2018January 31, 2024XIONG, YEreporter.nih.gov
Alcohol and Traumatic Brain Injury; Neuronal and Behavioral ConsequencesNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$657,000May 10, 2018March 31, 2024MOLINA, PATRICIA E.reporter.nih.gov
Mechanisms and intervention of cGAS signaling in brain trauma-induced neuroinflammation and neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2025$654,218August 1, 2025July 31, 2030WU, JUNFANGreporter.nih.gov
The Role of RNA Binding Motif 5 in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$654,062July 1, 2018June 30, 2024JACKSON, TRAVIS Creporter.nih.gov
Cortical Somatostatin Interneuron Dysfunction after Trauma: Role in Cognitive FlexibilityNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$639,155September 1, 2020June 30, 2024NOLAN, AMBER Lreporter.nih.gov
Behavioral- and bio-markers of subconcussion with controlled human head impactNIHNational Institute of Neurological Disorders and Stroke2021$635,540September 28, 2017July 31, 2024JEKA, JOHN JOSEPHreporter.nih.gov
Live video mind-body treatment to prevent persistent symptoms following mTBINIHNational Center for Complementary & Integrative Health2021 to 2024$631,756September 1, 2020August 31, 2025GREENBERG, JONATHANreporter.nih.gov
Sleep Management And Recovery after Traumatic Brain Injury in Kids (SMART-Kids): Evidence for targeting sleep to improve outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$623,616September 15, 2020August 31, 2025WILLIAMS, CYDNI NICOLEreporter.nih.gov
Head impact biomechanics, neurobehavioral health, and community perspectives on safety in youth ice hockeyNIHNational Institute of Neurological Disorders and Stroke2025$620,784May 16, 2025April 30, 2030STITZEL, JOEL DOUGLASreporter.nih.gov
Role of acid sphingomyelinase in the modulation of coagulation after traumatic brain injuryNIHNational Institute of General Medical Sciences2021 to 2022$609,900May 1, 2018April 30, 2024GOODMAN, MICHAELreporter.nih.gov
Characterizing reactive balance after mild traumatic brain injuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$607,323July 1, 2025June 30, 2030FINO, PETER Creporter.nih.gov
Upgrade the 14T Ultrahigh Field Horizontal MR Scanner for Rodent and ex-vivo ImagingNIHOffice of the Director, National Institutes of Health2021$600,000April 15, 2021April 14, 2024ROSEN, BRUCE Rreporter.nih.gov
Mitochondrial Modulation Therapy After Brain TraumaNIHNational Institute of Neurological Disorders and Stroke2025$587,521June 1, 2025April 30, 2030WIDER, JOSEPHreporter.nih.gov
ICP-TOF Mass Spectrometer for Ultrafast Elemental Mapping of Clinical and Preclinical BiospecimensNIHOffice of the Director, National Institutes of Health2024$582,750May 1, 2024April 30, 2025GOLDSTEIN, LEE E.reporter.nih.gov
Sex Differences in Brain Structure and Function After Sports-Related ConcussionNIHNational Institute of Neurological Disorders and Stroke2022$574,253August 1, 2017July 31, 2025KOERTE, INGA KATHARINAreporter.nih.gov
Adipokines as novel therapy to promote functional recovery after experimental traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2025$571,404May 30, 2025April 30, 2030CHEN, JUNreporter.nih.gov
Astrocyte-Specific IL-1RI Signaling Effects Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$563,384March 15, 2019February 29, 2024NEWELL, ELIZABETHreporter.nih.gov
Contributions of Brain Trauma to AD/ADRD Neuropathology, including CTE, and Resulting Clinical OutcomesNIHNational Institute of Neurological Disorders and Stroke2024$561,147August 1, 2024May 31, 2025MCKEE, ANN C.reporter.nih.gov
Biomechanics of the Human Brain During High-Severity Impacts: A Multimodal ApproachNIHNational Institute of Neurological Disorders and Stroke2025$559,820January 1, 2025December 31, 2029ALSHAREEF, AHMEDreporter.nih.gov
Metabolic Mechanisms of Recovery in Mild TBINIHNational Institute of Neurological Disorders and Stroke2023$557,776September 25, 2023August 31, 2024FIRESTEIN, BONNIE Lreporter.nih.gov
The neuroprotective role of proliferative reactive astrocytes in the hippocampus, synapse preservation and regeneration following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024$554,750July 1, 2024June 30, 2026GAO, XIANGreporter.nih.gov
Magnetoencephalography and Neurobehavioral Outcome of Pediatric Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$552,993March 10, 2017February 28, 2023MAX, JEFFREY EDWINreporter.nih.gov
Endogenous circadian clocks regulate NG2-glia regenerative potentialNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$545,687September 26, 2023August 31, 2028DEAN, TERRYreporter.nih.gov
Microglial process convergence following brain injuryNIHNational Institute of Neurological Disorders and Stroke2022$543,375August 1, 2022July 31, 2024LAFRENAYE, AUDREY Dreporter.nih.gov
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History (PATH)NIHNational Institute on Aging2022 to 2025$540,000August 1, 2022May 31, 2027LOBUE, CHRISTIAN BARRETTreporter.nih.gov
Regulation of Mesenchymal Stem Cell Secretome for Treatment of Microglia Damage in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022$539,000August 3, 2022July 31, 2024GANGARAJU, RAJASHEKHARreporter.nih.gov
G Protein Signaling in Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022$535,500July 1, 2022June 30, 2025ANDRES, DOUGLAS ALLENreporter.nih.gov
Targeted Nanotherapies for the Treatment of Brain DisordersNIHNational Institute of Neurological Disorders and Stroke2025$532,385August 1, 2025May 31, 2030SHARMA, ANJALIreporter.nih.gov
Analytical Validation of Tau and P-Tau as acute and subacute prognostic biomarkers for complicated mild TBINIHNational Institute of Neurological Disorders and Stroke2021$525,553August 15, 2020November 4, 2022WANG, KEVIN KA WANGreporter.nih.gov
Improving Prognostication for Traumatic Brain InjuryNIHNational Institute of General Medical Sciences2023 to 2025$522,436April 1, 2023March 31, 2027MAIGA, AMELIAreporter.nih.gov
Mechanisms and Clinical Impact of Myocardial Injury Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$522,042September 15, 2019May 31, 2025KRISHNAMOORTHY, VIJAYreporter.nih.gov
Gut Serotonergic Signaling in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2025$521,963August 1, 2025June 30, 2030NASR, ISAMreporter.nih.gov
Chronic Care Management of Geriatric Traumatic Brain InjuryNIHNational Institute on Aging2021 to 2024$502,518August 1, 2020May 31, 2025PAPPADIS, MONIQUE RENAEreporter.nih.gov
Betterbot: Promoting Accessible and Inclusive Mental Health Support for Individuals with Brain InjuryNIHNational Institute of Mental Health2025$499,887September 1, 2025August 31, 2026WEISMAN, HANNAH LESLIEreporter.nih.gov
Temporal Biomarker-Powered Immunotherapy Targeting GFAP for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021$499,065September 15, 2021August 31, 2024HASKINS, WILLIAM Ereporter.nih.gov
Investigating the potential impact of a low-fat high fiber diet in limiting TBI-induced neurodegenerative and inflammatory changes.NIHNational Institute of Neurological Disorders and Stroke2024$498,713July 19, 2024June 30, 2027ACHARYA, NIMISH KUMARreporter.nih.gov
Understanding and Controlling Neuro-immune Interactions Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$498,000September 1, 2022June 30, 2027WOFFORD, KATHRYN LEIGHreporter.nih.gov
Conformational properties of misfolded protein aggregates in cases involving the co-occurrence of prion disease and Alzehimer's disease or prion disease and CTENIHNational Institute on Aging2022 to 2023$497,998September 1, 2022May 10, 2024CALI, IGNAZIOreporter.nih.gov
Complete Mental Counts for Patients Recovering from Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2025$497,201September 1, 2025August 30, 2026CARMI, RANreporter.nih.gov
Traumatic axonal injury in the visual system: role of dual leucine zipper kinaseNIHNational Eye Institute2021$494,288April 1, 2017March 31, 2024KOLIATSOS, VASSILIS Ereporter.nih.gov
Cis proline directed proteotoxicity in the early development and therapy of traumatic brain injury and vascular dementiaNIHNational Institute on Aging2024 to 2025$492,812September 1, 2022August 31, 2027QIU, CHENXIreporter.nih.gov
Mitigating Post-Traumatic Epileptogenesis by Enhancing Synaptic Glutamate Transport via Long-Term Non-Bactericidal Beta-Lactam AdministrationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$486,750April 1, 2024March 31, 2027ROTENBERG, ALEXANDERreporter.nih.gov
Combine Genomics and Symptoms Data Driven Models to Discover Synergistic Combinatory Therapies for Alzheimer's DiseaseNIHNational Institute on Aging2021$486,147September 15, 2020May 31, 2025LI, FUHAIreporter.nih.gov
Characterizing the Relationship Between Delirium and Biological Age in Traumatic Brain Injury: Implications for Cognitive Decline in Older AdultsNIHNational Institute on Aging2024 to 2025$486,000August 1, 2024July 31, 2029LAHUE, SARA CATHERINEreporter.nih.gov
SCH: INT: Collaborative Research: Multimodal Signal Analysis and Data Fusion for Post-traumatic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$485,021May 1, 2019February 29, 2024DUNCAN, DOMINIQUEreporter.nih.gov
Orexin regulation of responses to brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$484,000April 1, 2023September 30, 2025COHEN, AKIVA Sreporter.nih.gov
A Longitudinal Evaluation of Psychophysiological and Motor Dysfunction following Concussion: Associations with Subsequent InjuryNIHNational Institute of Neurological Disorders and Stroke2025$483,673July 8, 2025May 31, 2030OLDHAM, JESSIE REIDreporter.nih.gov
Miniscope in vivo imaging of cumulative traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$480,316April 1, 2023March 31, 2025LIFSHITZ, JONATHANreporter.nih.gov
A Single Cell and Proteomic Precision Medicine Approach to Glyburide Responsive Contusion Expansion in Severe Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$479,542April 15, 2023March 31, 2026JHA, RUCHIRA MENKAreporter.nih.gov
Evidence-based intervention for Improved Head Impact Safety in Youth FootballNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$478,762March 18, 2021February 28, 2025URBAN, JILLIAN ELIZABETHreporter.nih.gov
Multi-modality Test for improving precision of TBI diagnosis in the elderly.NIHNational Institute of Neurological Disorders and Stroke2022$471,835June 15, 2022July 31, 2024VAN METER, TIMOTHY Ereporter.nih.gov
Point-of-Care Brain Magnetic Resonance Imaging in Children with Head Trauma (BRAINCHILD)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$470,250August 1, 2024July 31, 2026CHAUDHARI, PRADIPreporter.nih.gov
Post-trial Access, Clinical Care, Psychosocial Support, and Scientific Progress in Experimental Deep Brain Stimulation ResearchNIHNational Institute of Mental Health2025$466,410August 18, 2023May 31, 2027LAZARO-MUNOZ, GABRIELreporter.nih.gov
Understanding cell chirality and cell-cell interactions at neurovascular unit after brain injuryNIHNational Institute of Neurological Disorders and Stroke2024$465,752September 1, 2024August 31, 2027ZHANG, ZHIreporter.nih.gov
Digital Spatial Profiling of Hippocampal Subregions in Alzheimer’s Disease, Primary Age-Related Tauopathy, and Chronic Traumatic EncephalopathyNIHNational Institute on Aging2022$464,750August 15, 2022July 31, 2024RICHARDSON, TIMOTHY ERICreporter.nih.gov
In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PETNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$461,216January 1, 2021December 31, 2023RABINOVICI, GIL DANreporter.nih.gov
Role of Sarm1 in TBI-accentuated C9orf72 Frontotemporal DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$460,625February 1, 2023April 30, 2025HENNINGER, NILSreporter.nih.gov
Safety and Cognitive Effects of Acute Intermittent Hypoxia-Induced Neuroplasticity in TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$457,092January 1, 2021December 31, 2024GRAFMAN, JORDAN HENRYreporter.nih.gov
Applying human in vitro models to understand the link between trauma and tau pathologyNIHNational Institute of Neurological Disorders and Stroke2023$457,049September 15, 2023August 31, 2025FINAN, JOHN Dreporter.nih.gov
Predicting Dependency after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$456,885April 1, 2024March 31, 2029SNIDER, SAMUELreporter.nih.gov
Effect of intranasal HB-EGF treatment on brain glucose metabolism and inflammation after TBI in the developing brainNIHNational Institute of Neurological Disorders and Stroke2025$453,970June 1, 2025May 31, 2027SCAFIDI, JOSEPHreporter.nih.gov
Metabolic regulation of Neutrophil Extracellular Traps (NETs) in TBINIHNational Institute of Neurological Disorders and Stroke2025$453,860June 1, 2025April 30, 2030AHMED, MOHAMMAD EJAZreporter.nih.gov
The INSIGHT-ICU Study: Illuminating Neuropsychological dysfunction and Systemic Inflammatory mechanisms Gleaned after Hospitalization in Trauma-ICU StudyNIHNational Institute of General Medical Sciences2021$453,392January 1, 2017November 30, 2023PATEL, MAYUR Breporter.nih.gov
Traumatic axonopathy and Alzheimer tau propagationNIHNational Institute of Neurological Disorders and Stroke2023$450,313March 1, 2023February 28, 2026KOLIATSOS, VASSILIS Ereporter.nih.gov
iPPSIS: implanted Passive Pressure Sensor Interrogated with (ultra)-SoundNIHNational Institute of Biomedical Imaging and Bioengineering2021$450,081August 1, 2021July 31, 2024MYERS, DAVID RICHARDreporter.nih.gov
Aberrant PTEN signaling in chronically activated microglia drives tau pathology, neurodegeneration and cognitive decline following repetitive brain injuryNIHNational Institute on Aging2024$449,460June 15, 2024May 31, 2026OJO, JOSEPH Oreporter.nih.gov
The role of PPARγ in astrocyte pathobiology after exposure to repetitive mild traumatic brain injuryNIHNational Institute on Aging2023$449,444September 1, 2023August 31, 2025OJO, JOSEPH Oreporter.nih.gov
Traumatic Axonal Injury: Tau and Amyloid Pathogenesis in vitroNIHNational Institute of Neurological Disorders and Stroke2024$446,875May 28, 2024April 30, 2026SMITH, DOUGLAS HAMILTONreporter.nih.gov
J147 Treatment for Traumatic Brain Injury in Brain Damage and Long-Term Functional RecoveryNIHNational Institute of Neurological Disorders and Stroke2021$445,995September 7, 2021August 31, 2025JIN, RONGreporter.nih.gov
Influence of thalamic IL-33 signaling in aging-associated exacerbation of cognitive impairment after brain injury via microglial dysfunction and tau pathologyNIHNational Institute on Aging2025$445,757September 15, 2022June 30, 2027KANO, SHINICHIreporter.nih.gov
Methods and devices to assist and improve cerebrospinal fluid drainageNIHNational Institute of Neurological Disorders and Stroke2022$444,125July 1, 2022June 30, 2025BRITZ, GAVIN WAYNEreporter.nih.gov
Intranasal Delivery of Telomerase Reverse Transcriptase mRNA for Therapy ofTraumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022$444,125September 26, 2022August 31, 2024GODIN, BIANAreporter.nih.gov
Epilepsy after penetrating brain injuryNIHNational Institute of Neurological Disorders and Stroke2023$444,125September 21, 2023August 31, 2025BERTRAM, EDWARD Hreporter.nih.gov
Predictors of Low-risk Phenotypes after Traumatic Brain Injury Incorporating Proteomic Biomarker Signatures.NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$442,530August 1, 2023May 31, 2025HINSON, HOLLY ELAINEreporter.nih.gov
Establishing iPSC-based models to investigate the mechanistic interaction between neurotrauma and ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2025$438,606August 1, 2025July 31, 2027KISKINIS, EVANGELOSreporter.nih.gov
Molecular Mechanisms and Treatment of Diffuse Axonal InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$437,728October 18, 2022November 30, 2025KELLEY, BRIAN J.reporter.nih.gov
Quantification of brain-derived extracellular vesicle microRNAs in blood by a liposome-mediated CRISPR assay for traumatic brain injury detectionNIHNational Institute of Neurological Disorders and Stroke2022$437,348September 1, 2022August 31, 2025HU, TONY Y.reporter.nih.gov
Targeting Cholinergic Deficits with Retinoic Acid after TBINIHNational Institute of Neurological Disorders and Stroke2023$437,250August 11, 2023July 31, 2025DIXON, C EDWARDreporter.nih.gov
Neurobehavioral and pathophysiological effects of traumatic brain injury in spontaneously hypertensive ratsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$437,250April 16, 2024November 30, 2026BONDI, CORINA OANAreporter.nih.gov
The epichaperome: A novel therapeutic target for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$437,250April 1, 2024March 31, 2027DIXON, C EDWARDreporter.nih.gov
Vestibular and neck muscle contributions to head control in response to induced head perturbations and falls in balance-impaired older adultsNIHNational Institute on Aging2023$435,582September 30, 2023September 29, 2025SOSNOFF, JACOB J.reporter.nih.gov
Virtual Reality-based Rehabilitation for Children with Traumatic Brain InjuriesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$435,228September 8, 2020February 28, 2025SHEN, JIABINreporter.nih.gov
Pharmacological inhibition of NEP-like enzymes in traumatic brain injury and dementiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$434,225May 15, 2024April 30, 2027MARR, ROBERT ANTHONYreporter.nih.gov
An Enriched, Immersive Rehabilitative Environment for Those with Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$430,438September 1, 2024February 28, 2027SULZER, JAMESreporter.nih.gov
DISCOVERY OF NOVEL TARGETS FOR POST-TRAUMATIC HEADACHENIHNational Institute of Neurological Disorders and Stroke2023$428,250April 15, 2023March 31, 2026CAO, YUQINGreporter.nih.gov
Does Contact Sport Induce Fibrillar Amyloid Deposition in the Brain?NIHNational Institute of Neurological Disorders and Stroke2021$427,250September 22, 2021February 28, 2025VASKA, PAULreporter.nih.gov
Behavioral and axonal impacts of thalamic microglial process convergence following diffuse brain injuryNIHNational Institute of Neurological Disorders and Stroke2022$426,938September 10, 2022August 31, 2025LAFRENAYE, AUDREY Dreporter.nih.gov
Role and Function of Peroxisomal Ether Phospholipids in TBINIHNational Institute of Neurological Disorders and Stroke2021$424,875April 1, 2021September 30, 2023SARKAR, CHINMOYreporter.nih.gov
Targeting TREM2 AD/ADRD risk and immunometabolism in human microgliaNIHNational Institute of Neurological Disorders and Stroke2023$424,875September 1, 2023August 31, 2025POLSTER, BRIAN Mreporter.nih.gov
Sleep and Circadian Rhythm Disorders After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023$423,624September 18, 2023August 31, 2025BARBER, ANNIKA FITZPATRICKreporter.nih.gov
Therapeutic Value of BNC-1 in Addressing Tau Pathology in TBINIHNational Institute on Aging2024$423,500September 15, 2024August 31, 2026BACHSTETTER, ADAM Dreporter.nih.gov
Influence of Age and Sex on Cerebral Edema Formation Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$422,805May 5, 2022April 30, 2027THARAKAN, BINUreporter.nih.gov
Penetrating brain injury and copper fragments in a rat model of posttraumatic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022$422,698June 1, 2022May 31, 2025DUDEK, F. EDWARDreporter.nih.gov
The role of mitochondrial fission in TBI outcomeNIHNational Institute of Neurological Disorders and Stroke2021$421,361September 15, 2017February 29, 2024WAXHAM, M. NEALreporter.nih.gov
Drug repurposing for Alzheimer’s disease-related inflammation caused by a TBINIHNational Institute on Aging2023 to 2024$420,750February 15, 2023December 31, 2024BACHSTETTER, ADAM Dreporter.nih.gov
N-acetylserotonin alleviates neurotoxicity in alcohol misuse following TBINIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$420,541May 1, 2023April 30, 2026WANG, XINreporter.nih.gov
Integrative Data Analysis to Identify Persistent Post-Concussion Deficits and Subsequent Musculoskeletal Injury RiskNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$419,798September 3, 2021July 31, 2024BUCKLEY, THOMAS A.reporter.nih.gov
Effects of Docosahexaenoic Acid on Oxidative Stress White Matter Injury and Brain Inflammation in a Pre-Clinical Model of Pediatric TBINIHNational Institute of Neurological Disorders and Stroke2021$419,375May 1, 2021October 31, 2023SCHOBER, MICHELLE ELENAreporter.nih.gov
Noninvasive Vagus Nerve Stimulation for Treatment of Brain Injury (nVNS-TBI) in RatsNIHNational Institute of Neurological Disorders and Stroke2022$419,375September 23, 2022August 31, 2025DIVANI, AFSHIN ANDREreporter.nih.gov
Lateral habenula circuit dysregulation in mild traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$419,365January 1, 2021December 31, 2024NUGENT, FERESHTEH Sreporter.nih.gov
Utilizing head motion measurements integrated with clinical outcomes to inform post-concussion return to play protocols in gymnasticsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$418,250February 14, 2022January 31, 2025URBAN, JILLIAN ELIZABETHreporter.nih.gov
Sensory Integration for Spatial Navigation After ConcussionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$415,744December 1, 2023November 30, 2026FINO, PETER Creporter.nih.gov
Evaluating astrocyte loss after traumatic brain injury in initiation of post-traumatic epilepsyNIHNational Institute of Neurological Disorders and Stroke2021$414,927January 15, 2018December 31, 2021ROBEL, STEFANIEreporter.nih.gov
VRC: Reduction of Vision Loss with Early Interventions After Optic Nerve InjuryNIHNational Eye Institute2022 to 2023$405,600September 1, 2022February 28, 2025BRECHA, NICHOLAS C.reporter.nih.gov
Role of UCHL1 in Axonal Injury and Recovery after TBINIHNational Institute of Neurological Disorders and Stroke2021$404,662July 1, 2017June 30, 2023GRAHAM, STEVEN Hreporter.nih.gov
Mechanisms of Chronic Blood-Brain Barrier Dysfunction after Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2025$404,100January 1, 2025December 31, 2029WHALEN, MICHAEL Jreporter.nih.gov
Spreading Depolarizations and Brain Dysfunction Following Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$404,028April 15, 2019November 30, 2022NGWENYA, LAURA BENJAMINreporter.nih.gov
RESET: Regulation of Emotion, Sleep Extension, and mTBINIHNational Institute of Mental Health2025$403,937January 1, 2025December 31, 2027KURDZIEL, LAURAreporter.nih.gov
Innovative Non-Invasive Imaging of Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022$400,685September 1, 2022August 31, 2025RINALDI-RAMOS, CARLOS Mreporter.nih.gov
High-Throughput In Vitro Analyses of Trauma-Induced TauopathyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$399,750April 1, 2023March 31, 2026ALFORD, PATRICK Wreporter.nih.gov
Oxidation of K+ channels mediates an amyloidogenic pathway common to Alzheimer's disease and TBINIHNational Institute on Aging2023$397,500February 1, 2019November 30, 2024SESTI, FEDERICOreporter.nih.gov
The cell-specific neurodegenerative potential of mitochondria post-traumatic brain injuryNIHNational Institute on Aging2024 to 2025$397,419August 1, 2024July 31, 2027LIAUDANSKAYA, VOLHAreporter.nih.gov
Biomechanical Basis of Sex Differences in Concussion and SubconcussionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$391,804June 1, 2024May 31, 2027JI, SONGBAIreporter.nih.gov
Mechanistic underpinnings of trigeminal nerve stimulation as a therapeutic approach to TBINIHNational Center for Complementary & Integrative Health2025$391,215September 1, 2025August 31, 2027TITHOF, JEFFREYreporter.nih.gov
Diminished Motor Performance in Athletes Cleared to Return to Play after Sports-Related ConcussionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$391,184September 20, 2019February 28, 2025STEPHENS, JACLYNreporter.nih.gov
Neural reorganization in divergent TBI recovery responsesNIHNational Institute of Neurological Disorders and Stroke2022$390,500September 1, 2022August 31, 2024WEST, FRANKLIN Dreporter.nih.gov
The Effect of Sex Dimorphisms on TBI Injury and RecoveryNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$390,500June 15, 2023May 31, 2026WEST, FRANKLIN Dreporter.nih.gov
Sharp wave ripple stimulation as a potential strategy to enhance memory after TBINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$390,000June 15, 2024May 31, 2027DASH, PRAMOD Kreporter.nih.gov
Predicting recovery after TBI: Development and comparison of MR-supplemented models using non-parametric and machine learning multimodal fusionNIHNational Institute of Biomedical Imaging and Bioengineering2024$389,813August 5, 2024July 31, 2026MONTI, MARTIN MAXreporter.nih.gov
Caveolin-1 contributes to the long-term function and structure of the neurovascular unit after juvenile concussionNIHNational Institute of Neurological Disorders and Stroke2025$389,319August 1, 2021February 28, 2027OBENAUS, ANDREreporter.nih.gov
Deregulation of Sleep/Wake Homeostasis by Binge Alcohol Use Following Traumatic Brain InjuryNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2023$387,735August 15, 2022May 31, 2025LIU, ANDREW C.reporter.nih.gov
Molecular Therapies to Promote White Matter Restoration After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021$386,585September 30, 2015May 31, 2023DIXON, C EDWARDreporter.nih.gov
Brain Macrophages After Brain Injury Leads to Negative Behavioral OutcomesNIHNational Institute of Neurological Disorders and Stroke2021$384,725August 1, 2021July 31, 2025LI, YINGreporter.nih.gov
Epigenetic Influences on Neurobehavioral Recovery following Pediatric Traumatic Brain InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$384,389September 11, 2019August 31, 2024TREBLE-BARNA, AMERYreporter.nih.gov
Regulation of efferocytosis in the brain following traumatic injuryNIHNational Institute of Neurological Disorders and Stroke2025$380,556August 8, 2025May 31, 2030SOLIMAN, EMANreporter.nih.gov
Role of Notch signaling in regulating post-TBI neurogenesis and plasticityNIHNational Institute of Neurological Disorders and Stroke2021$379,419February 1, 2017January 31, 2024SUN, DONGreporter.nih.gov
Investigating cerebrovascular dysfunction and cerebral atrophy in severe traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023$379,171September 19, 2023August 31, 2025KARUMBAIAH, LOHITASHreporter.nih.gov
Predictors of Low-risk Phenotypes after Traumatic Brain Injury Incorporating Proteomic Biomarker SignaturesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$372,471June 1, 2020February 28, 2023HINSON, HOLLY ELAINEreporter.nih.gov
Evaluating astrocyte loss after traumatic brain injury in initiation of post-traumatic epilepsyNIHNational Institute of Neurological Disorders and Stroke2022$364,116January 15, 2018June 30, 2023ROBEL, STEFANIEreporter.nih.gov
Microvascular Neuroimaging in Age-related Alzheimer's Disease and TauopathiesNIHNational Institute on Aging2023 to 2025$363,408August 1, 2023April 30, 2028HUA, NINGreporter.nih.gov
Effects of Extracellular Mechanics on Mechanosensory and Central Neuron FunctionNIHNational Institute on Aging2022 to 2025$358,155September 23, 2019December 31, 2025FRANCO, JOY ANNreporter.nih.gov
Mechanisms of cognitive dysfunction after repetitive closed head injury in adolescent miceNIHNational Institute of Neurological Disorders and Stroke2021$356,343July 1, 2018March 31, 2023WHALEN, MICHAEL Jreporter.nih.gov
Chemical Reprogramming of Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021$354,375June 15, 2017May 31, 2022ZHANG, CHUN-LIreporter.nih.gov
Traumatic Brain Injury Across the Lifespan in ZambiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$351,825September 3, 2021August 31, 2025HYDER, ADNAN Areporter.nih.gov
Blood-Biomarkers and Risk Factors of Acute Brain Injury associated with Neurodisability in Ugandan Children [BRAIN-Child]NIHNational Institute of Neurological Disorders and Stroke2022 to 2023$351,649August 15, 2022July 31, 2025DATTA, DIBYADYUTIreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Boston University Medical CampusBoston, MA22$40.8 million0$0
University of Maryland BaltimoreBaltimore, MD16$35.7 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA25$34 million0$0
University of Michigan at Ann ArborAnn Arbor, MI8$32.2 million0$0
University of PennsylvaniaPhiladelphia, PA21$32.1 million0$0
University of California Los AngelesLos Angeles, CA14$31.8 million0$0
Massachusetts General HospitalBoston, MA19$26.3 million0$0
Ohio State UniversityColumbus, OH17$22.7 million0$0
University of UtahSalt Lake City, UT12$21.3 million0$0
Washington UniversitySaint Louis, MO10$20.5 million0$0
University of California, San DiegoLa Jolla, CA9$19.4 million0$0
Yale UniversityNew Haven, CT6$17.8 million0$0
University of WashingtonSeattle, WA9$17.8 million0$0
Johns Hopkins UniversityBaltimore, MD9$16.7 million0$0
University of California, San FranciscoSan Francisco, CA12$15.2 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY7$14.1 million0$0
Virginia Commonwealth UniversityRichmond, VA9$13.4 million0$0
University of MinnesotaMinneapolis, MN5$13.1 million0$0
University of KentuckyLexington, KY12$12.9 million0$0
University of Southern CaliforniaLos Angeles, CA8$12.9 million0$0
University of FloridaGainesville, FL7$12.8 million0$0
Columbia University Health SciencesNew York, NY6$10.8 million0$0
Oregon Health & Science UniversityPortland, OR5$10.7 million0$0
University of RochesterRochester, NY5$10.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY6$10.4 million0$0
Laureate Institute for Brain ResearchTulsa, OK1$10.3 million0$0
Florida International UniversityMiami, FL1$10 million0$0
Albert Einstein College of MedicineBronx, NY2$9.6 million0$0
University of Colorado DenverAurora, CO6$9.6 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM2$9.5 million0$0
Ut Southwestern Medical CenterDallas, TX7$9.3 million0$0
Vanderbilt University Medical CenterNashville, TN6$9.3 million0$0
University of Vermont & ST Agric CollegeBurlington, VT3$9.2 million0$0
Seattle Children's HospitalSeattle, WA5$9.1 million0$0
Duke UniversityDurham, NC7$9.1 million0$0
Northwestern University at ChicagoChicago, IL6$8.9 million0$0
University of Alabama at BirminghamBirmingham, AL7$8.5 million0$0
University of Miami School of MedicineCoral Gables, FL5$8.5 million0$0
University of Colorado at BoulderBoulder, CO2$8.2 million0$0
Augusta UniversityAugusta, GA5$8 million0$0
University of VirginiaCharlottesville, VA5$7.8 million0$0
University of California-RiversideRiverside, CA5$7.1 million0$0
Seattle Inst for Biomedical/clinical ResSeattle, WA3$6.9 million0$0
Sri InternationalMenlo Park, CA1$6.6 million0$0
Medical University of South CarolinaCharleston, SC2$6.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX6$6.5 million0$0
New York University School of MedicineNew York, NY4$6.4 million0$0
University of Wisconsin-MilwaukeeMilwaukee, WI1$5.9 million0$0
Medical College of WisconsinMilwaukee, WI6$5.8 million0$0
Indiana University IndianapolisIndianapolis, IN5$5.8 million0$0
Research Inst Nationwide Children's HospColumbus, OH4$5.6 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA4$5.6 million0$0
Indiana UniversityBloomington, IN3$5.4 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA5$5.4 million0$0
Lovelace Biomedical Research InstituteAlbuquerque, NM3$5.1 million0$0
Texas A&m University Health Science CTRCollege Station, TX4$5.1 million0$0
University of CincinnatiCincinnati, OH6$4.9 million0$0
University of ArizonaTucson, AZ5$4.8 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN1$4.7 million0$0
University of Illinois at ChicagoChicago, IL3$3.8 million0$0
University of California-IrvineIrvine, CA4$3.8 million0$0
University of Georgia Research Foundation IncAthens, GA6$3.7 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA2$3.6 million0$0
ST. Joseph's Hospital and Medical CenterPhoenix, AZ3$3.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA2$3.3 million0$0
New Jersey Institute of TechnologyNewark, NJ2$3.3 million0$0
George Washington UniversityWashington, DC3$3.1 million0$0
Georgia Tech Research CorporationAtlanta, GA3$3 million0$0
Savior Brain Inc.Vienna, VA2$2.9 million0$0
Georgetown UniversityWashington, DC5$2.7 million0$0
Arizona State UniversityScottsdale, AZ2$2.6 million0$0
Brigham and Women's HospitalBoston, MA6$2.6 million0$0
University of Texas Med BR GalvestonGalveston, TX3$2.6 million0$0
Wake Forest University Health SciencesWinston-Salem, NC8$2.6 million0$0
Trustees of Boston UniversityBoston, MA1$2.6 million0$0
Aivocode, LLPEncinitas, CA1$2.6 million0$0
BloodworksSeattle, WA1$2.4 million0$0
Villanova UniversityVillanova, PA1$2.4 million0$0
Emory UniversityAtlanta, GA4$2.3 million0$0
Colorado State UniversityFort Collins, CO3$2.3 million0$0
Beth Israel Deaconess Medical CenterBoston, MA4$2.3 million0$0
Henry Ford Health + Michigan State University Health SciencesEast Lansing, MI3$2.2 million0$0
Gryphon Bio, Inc.South San Francisco, CA2$2.2 million0$0
Rutgers University New BrunswickNew Brunswick, NJ3$2.2 million0$0
University of South FloridaTampa, FL3$2.2 million0$0
C. Light Technologies, Inc.Berkeley, CA1$2.2 million0$0
Methodist Hospital Research InstituteHouston, TX3$2.1 million0$0
Baylor College of MedicineHouston, TX1$2.1 million0$0
Massachusetts Eye and Ear InfirmaryBoston, MA2$2.1 million0$0
Upstate Medical UniversitySyracuse, NY1$2.1 million0$0
Bmseed, LLCTempe, AZ1$2.1 million0$0
University of Massachusetts AmherstAmherst, MA1$2.1 million0$0
University of IowaIowa City, IA3$2.1 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH1$2 million0$0
University of California at DavisDavis, CA1$2 million0$0
Adm Diagnostics, Inc.Northbrook, IL1$2 million0$0
University of HoustonHouston, TX1$1.9 million0$0
Hugo W. Moser Res Inst Kennedy KriegerBaltimore, MD2$1.9 million0$0
Roskamp Institute, Inc.Sarasota, FL5$1.9 million0$0
Kessler Foundation, Inc.East Hanover, NJ1$1.8 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025279$181,604,5170$0
2024314$190,722,2270$0
2023326$186,335,6960$0
2022331$199,176,7080$0
2021310$174,169,2330$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 4 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 424 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 424 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 424 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 424 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 424 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 424 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 424 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 424 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 424 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 424 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 424 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 424 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 424 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 424 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 424 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 424 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.