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Data / Research funding / Tickborne Diseases

Tickborne Diseases: 363 NIH awards ($433.4M) to 142 organizations

363 NIH awards ($433.4M) in the NIH spending category Tickborne Diseases, to 142 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

363 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Vermont Biomedical Research Network-Vermont INBRENIHNational Institute of General Medical Sciences2021 to 2025$19,534,463September 30, 2001June 30, 2030FRANCKLYN, CHRISTOPHER Sreporter.nih.gov
Lyme Disease: B cell epitope discovery and mechanisms of antibody protectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,722,146September 16, 2019September 15, 2024MANTIS, NICHOLAS J.reporter.nih.gov
B Cell Epitope Discovery and Mechanisms of Antibody Protection: Responses to Dengue 4, Powassan, Chikungunya, and Venezuelan Equine Encephalitis VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,634,396September 16, 2023September 15, 2024FREMONT, DAVEDreporter.nih.gov
Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,573,382September 1, 2021August 31, 2027NIGROVIC, LISE E.reporter.nih.gov
Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,526,401July 17, 2020June 5, 2025SAKUNTABHAI, ANAVAJreporter.nih.gov
Comparative systems biology of apicomplexan cell divisionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,447,470July 21, 2022June 30, 2027GUBBELS, MARC-JANreporter.nih.gov
DNA damage response and repair of a broken chromosomeNIHNational Institute of General Medical Sciences2021 to 2025$5,083,668June 1, 2018May 31, 2028HABER, JAMES Ereporter.nih.gov
Evaluation of an OMV-adjuvanted Chimeritrope Vaccine against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,961,891September 30, 2018September 29, 2023MORICI, LISAreporter.nih.gov
IgE antibody responses to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal) in murine and human atherosclerosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,866,733July 1, 2022June 30, 2027ERICKSON, LOREN Dreporter.nih.gov
Heritable immunization of the white-footed mouse reservoir of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,657,626September 1, 2021August 31, 2026ESVELT, KEVINreporter.nih.gov
IgE antibodies to the mammalian oligosaccharide galactose-alpha-1, 3-galactose (alpha-gal): immunology, epidemiology and relevance to allergic and inflammatory diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,621,686July 1, 1984May 31, 2028PLATTS-MILLS, THOMAS A.reporter.nih.gov
Development of the INI-4001 and INI-2002 adjuvants within the context of a vaccine to prevent Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,583,801September 30, 2018September 29, 2024EVANS, JAYreporter.nih.gov
Molecular elucidation of the Francisella tularensis virulence mechanismNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,049,782May 21, 2021April 30, 2027SCHUMACHER, MARIAreporter.nih.gov
Innovations in Functional B Cell Epitope Discovery for Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,031,164September 16, 2024September 15, 2026MANTIS, NICHOLASreporter.nih.gov
Functional B-cell Epitope Discovery for Arthropod-Borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,708,329September 16, 2024September 15, 2027reporter.nih.gov
PANDAA for universal, pan-lineage molecular detection of Crimean-Congo Hemorrhagic Fever virus.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,656,578March 24, 2021July 31, 2027MACLEOD, IAIN JAMESreporter.nih.gov
Fosinopril analogs for the treatment of human babesiosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,646,365April 21, 2021March 31, 2027BEN MAMOUN, CHOUKRIreporter.nih.gov
The Tick Immune Response During Microbial InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,501,084December 1, 2015May 31, 2027PEDRA, JOAOreporter.nih.gov
Rickettsia-host interface and multiple paths to invasionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,450,818June 15, 2016May 31, 2027RAHMAN, MOHAMMED SAYEEDURreporter.nih.gov
Microbial Determinants of Excessive Inflammation and Severe Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$3,315,179September 19, 2025August 31, 2029STRLE, KLEMENreporter.nih.gov
The roles of ceramide and its derivatives in A. phagocytophilum pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,301,707June 6, 2018May 31, 2028CARLYON, JASON Areporter.nih.gov
B cell Epitope Discovery and Mechanisms of Antibody Protection for Enterovirus and Bunyavirus Entry ProteinsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,291,808September 16, 2024September 15, 2026reporter.nih.gov
A novel Lyme disease vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,240,479June 7, 2022May 31, 2027FIKRIG, EROLreporter.nih.gov
Development and Field Testing of a Novel Reservoir Targeted Antibiotic Against Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,201,446May 15, 2020April 30, 2026HU, LINDEN Treporter.nih.gov
Rational development of a vaccine against tick-borne rickettsiosesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,166,318August 1, 2022July 31, 2027FANG, RONG MEGANreporter.nih.gov
Analysis of a novel Crimean-Congo hemorrhagic fever vaccine and its mechanism of protection in rodent modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,145,040August 25, 2022July 31, 2026SCHNELL, MATTHIAS JOHANNESreporter.nih.gov
A peptide-based point-of-care vertical flow assay for the rapid diagnosis of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,023,104June 24, 2020June 30, 2025ARNABOLDI, PAUL MICHAELreporter.nih.gov
DEVELOPMENT OF COVALENTLY BOUND HYALURONIC ACID AS AN ADJUVANT FOR MULTIVALENT LYME DISEASE VACCINENIHNational Institute of Allergy and Infectious Diseases2024$2,999,999September 30, 2024September 29, 2027PETILLO, PETER Areporter.nih.gov
Intranasal Vaccine Against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,988,409July 12, 2022June 30, 2026GOMES-SOLECKI, MARIAreporter.nih.gov
Mechanisms of SFG Rickettsia-Host InteractionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,971,223August 12, 2021July 31, 2030LAMASON, REBECCA Lreporter.nih.gov
Mechanisms of Rickettsia invasion, intracellular survival, and actin-based motilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,937,177September 1, 2014August 31, 2028WELCH, MATTHEW Dreporter.nih.gov
The roles of Lyme spirochete adhesins in hematogenous disseminationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,886,252February 10, 2022January 31, 2027COBURN, JENIFER Lreporter.nih.gov
Structure-Function Relationships in the Spirochetal Flagellar MotorNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,865,323February 15, 2010May 31, 2027LIU, JUNreporter.nih.gov
High accuracy automated tick classification using computer visionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,863,916April 18, 2022September 30, 2026GOODWIN, AUTUMNreporter.nih.gov
Preclinical Development of a Crimean-Congo Hemorrhagic Fever Virus VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,862,279July 15, 2020June 30, 2026GEISBERT, THOMAS WILLIAMreporter.nih.gov
Multivalent Tick-Microbe targeted Lyme disease vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,836,037July 20, 2020June 30, 2027PAL, UTPALreporter.nih.gov
Genetic architecture of host response to tickborne disease in Peromyscus leucopusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,831,395September 17, 2020August 31, 2025LONG, ANTHONY DOUGLASreporter.nih.gov
Polymeric matrix loaded with tick repellent or toxic compositions for incorporation into fabrics or for granular dispersalNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,775,723September 23, 2022August 31, 2025BANFIELD, MICHAEL GILBERTreporter.nih.gov
Hybrid ELISA: Simple and specific one-tier assay for Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,764,666March 6, 2019August 31, 2027LEVIN, ANDREW E.reporter.nih.gov
Molecular basis of immunity to tick-borne rickettsiosesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,758,756September 1, 2021August 31, 2027KIM, HWAN KEUNreporter.nih.gov
Targeting Cyclic Dinucleotide Signaling Pathways to Interrupt the Nature Cycle of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,734,150June 9, 2020May 31, 2026YANG, X. FRANKreporter.nih.gov
Host Metabolic Biosignatures for the Diagnosis of Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,695,774June 19, 2019May 31, 2025BELISLE, JOHN Treporter.nih.gov
Regulatory Pathways in Borrelial PathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,694,240August 5, 2022July 31, 2027SKARE, JON Treporter.nih.gov
Understanding alpha-gal red meat allergyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,615,501September 24, 2018January 31, 2029COMMINS, SCOTT PALMERreporter.nih.gov
Tick Saliva and Pathogen TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,544,342May 9, 2018June 30, 2029PEDRA, JOAOreporter.nih.gov
Vaccines for Prevention of RG3 and RG4 Emerging Tickborne Viral DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,523,497August 20, 2021July 31, 2026VERARDI, PAULO Hreporter.nih.gov
Development of vaccines targeting a tick-borne phlebovirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,499,856July 10, 2020June 30, 2025BATES, PAULreporter.nih.gov
Toward novel therapies against Lyme disease through the inhibition of lysinoalaine cross-linking in the bacterial flagella.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,405,876August 16, 2021July 31, 2025CRANE, BRIAN Rreporter.nih.gov
Cyclic di-AMP-dependent signaling in tickborne relapsing fever BorreliaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,380,916August 8, 2022July 31, 2027BLEVINS, JON SCOTTreporter.nih.gov
Role of human innate immune mutations in loss of tolerance to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,344,769September 8, 2020August 31, 2025HU, LINDEN Treporter.nih.gov
Virulence Mechanisms of Multifunctional Borrelial ProteinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,337,463June 15, 2020August 16, 2024GARCIA, BRANDON LEEreporter.nih.gov
Reassortment of Bunyavirus in ticks and animal modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,326,633August 19, 2022July 31, 2027JUNG, JAE Ureporter.nih.gov
Investigations of Lyme spirochete transmission as a complex network of microbial and ecological interactionsNIHNational Institute of General Medical Sciences2022 to 2025$2,315,379September 16, 2022July 31, 2027COURET, JANNELLEreporter.nih.gov
Identity, function and control of Francisella effectors encoded outside its pathogenicity islandNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,279,849July 1, 2019June 30, 2025MOUGOUS, JOSEPH DAVIDreporter.nih.gov
Development of a Virus-Like Particle Vaccine for Powassan VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,265,539June 1, 2020May 31, 2026HIRSCH, ALEC Jreporter.nih.gov
SFTSV nonstructural protein NSs-mediated immunopathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,260,994July 1, 2018June 30, 2024JUNG, JAE Ureporter.nih.gov
Develop a candidate subunit vaccine for Powassan Virus and West Nile virus adjuvanted with Alhydroxiquim-IINIHNational Institute of Allergy and Infectious Diseases2022$2,258,969September 30, 2018September 29, 2023DAVID, SUNILreporter.nih.gov
Tickborne SFTS Virus Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,258,000August 3, 2020July 31, 2026JUNG, JAE Ureporter.nih.gov
US-UK Collab: Modelling reassortment at the cellular, clinical, and phylogenetic level in emerging BunyavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,245,998July 1, 2021June 30, 2027MOLINA-PARIS, CARMENreporter.nih.gov
Developing New Statistical Methods for Vector-Borne Disease Surveillance to Improve Accuracy while Reducing CostNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,240,192September 19, 2023July 31, 2028SELF, STELLA COKER WATSONreporter.nih.gov
ANTIBODY-BASED PROTECTION AGAINST FLAVIVIRUSESNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,212,878September 15, 2007January 31, 2029DIAMOND, MICHAEL Sreporter.nih.gov
OspC and its role in defining host range and dissemination propertiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,211,024August 1, 2022July 31, 2026MARCONI, RICHARD Treporter.nih.gov
SpoVG and PlzA Regulation of Lyme Disease Spirochete Infection ProcessesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,207,935April 1, 2020March 31, 2026STEVENSON, BRIANreporter.nih.gov
Composition, Atomic Structure and Function of the Francisella Type 6 Secretion System, a Distinct Subtype Essential for Phagosomal Escape, Intracellular Replication, and VirulenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,198,656September 21, 2020August 31, 2025HORWITZ, MARCUS AARONreporter.nih.gov
Rocky Mountain Spotted Fever Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,192,703September 1, 2021August 31, 2027GANTA, ROMAN R.reporter.nih.gov
Borrelia gene products critical for natural infection cycleNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,181,619July 1, 2009July 31, 2025PAL, UTPALreporter.nih.gov
Role of IgE in human disease and immunity to ticksNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,139,543March 20, 2024January 31, 2026SMITH, SCOTT ALANreporter.nih.gov
Mechanisms of viral RNA maturation by co-opting cellular exonucleasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,134,101June 1, 2023May 31, 2027KIEFT, JEFFREY Sreporter.nih.gov
Intra-tick and intra-host infection dynamics of a tick-borne bunyavirusNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,092,645July 1, 2022June 30, 2027HERMANCE, MEGHAN ELIZABETHreporter.nih.gov
PlzA, cyclic-di-GMP and the enzootic cycle for Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,090,540November 18, 2022October 31, 2027MARCONI, RICHARD Treporter.nih.gov
Mechanism and Inhibition of Thogotovirus EntryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,085,008November 22, 2022October 31, 2027BOON, ADRIANUS CMreporter.nih.gov
New tools for tick-borne pathogen surveillanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,075,697December 8, 2022November 30, 2027OLIVER, JONATHAN Dreporter.nih.gov
Field trial and modeling of transmission blocking vaccine to prevent Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,072,628June 19, 2019May 31, 2025BROWN, GRANT Dreporter.nih.gov
The roles of Anaplasma phagocytophilum surface proteins in infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,062,336July 15, 2007June 30, 2027CARLYON, JASON Areporter.nih.gov
Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,049,089July 11, 2022June 30, 2027SHAW, DANA KATHLEENreporter.nih.gov
Vanderbilt University Medical Center (VUMC) CoFAR Clinical Research CenterNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,036,652March 14, 2024February 28, 2031BACHARIER, LEONARD Breporter.nih.gov
Germline Transformation of TicksNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,013,002May 11, 2023April 30, 2028GULIA-NUSS, MONIKAreporter.nih.gov
FH-Fc as a Pre-Exposure Prophylactic for Tickborne DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,000,000July 17, 2020April 30, 2025WYCOFF, KEITHreporter.nih.gov
Commercialization Readiness Pilot (CRP) program support for: Ultra-sensitive, direct-from-blood, molecular detection of Borrelia infections.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,000,000April 2, 2024March 31, 2027SINGER, ALONreporter.nih.gov
Targeted Prevention of Human EhrlichiosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,991,816August 17, 2021July 31, 2027RIKIHISA, YASUKOreporter.nih.gov
Development of an automated IVD for the ultra-sensitive, direct, molecular detection of Borrelia for early Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,972,995June 15, 2020May 31, 2024SINGER, ALONreporter.nih.gov
A point of care vertical flow assay for the direct detection of Babesia microti and the serodiagnosis of Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,933,868July 1, 2024February 28, 2027DATTWYLER, RAYMOND JAMESreporter.nih.gov
Understanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,906,728September 19, 2008January 31, 2027LI, CHUNHAO CHRISreporter.nih.gov
Discovery of early immunologic biomarkers for risk of PTLDS through machine learning-assisted broad temporal profiling of humoral immune responseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,885,162July 7, 2023June 30, 2028WOODBURY, NEAL WALTERreporter.nih.gov
Efficacy of novel reservoir-host targeted bait formulations against a tick-borne pathogenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,875,000September 1, 2021August 31, 2026SESHU, JANAKIRAMreporter.nih.gov
Unlocking serology’s secrets: harnessing novel immune biomarkers to predict Lyme disease progression and recoveryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,872,987July 1, 2023June 30, 2028TAL, MICHAL CASPIreporter.nih.gov
Virulence regulation by BadR in the Lyme disease spirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,868,750March 24, 2021February 28, 2027OUYANG, ZHIMINGreporter.nih.gov
Determinants of Post-Treatment Phenotypes in Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,868,460July 1, 2023June 30, 2028AUCOTT, JOHNreporter.nih.gov
Auto-antibodies as predictive markers for Post treatment Lyme Disease SyndromeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,830,220July 5, 2023June 30, 2028HU, LINDEN Treporter.nih.gov
Antiviral and immunomodulatory effects of interferon lambda in the skinNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,784,166March 13, 2023February 29, 2028LAZEAR, HELENreporter.nih.gov
Impacts of phenology on disease transmission dynamicsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,776,375August 1, 2023July 31, 2028BRISSON, DUSTINreporter.nih.gov
Antibody-mediated immunity to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,759,416March 8, 2021February 28, 2027BAUMGARTH, NICOLEreporter.nih.gov
Cellular and humoral immunity in Lyme arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,748,421January 8, 2019June 30, 2024STEERE, ALLEN Creporter.nih.gov
Origin of the innate immunity suppression caused by nairovirus' protease activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,738,279September 16, 2020August 31, 2025PEGAN, SCOTT DUSANreporter.nih.gov
Peptide-vaccine development against Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,724,972May 15, 2020April 30, 2026BARBIER, MARIETTEreporter.nih.gov
Structure-based Vaccine Design for CCHFVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,714,028June 25, 2020November 30, 2025MCLELLAN, JASON SCOTTreporter.nih.gov
Antigen Discovery and Vaccine Development for Human Babesia ParasitesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,675,000May 13, 2020April 30, 2026BEN MAMOUN, CHOUKRIreporter.nih.gov
Leveraging environmental drivers to predict vector-borne disease transmissionNIHNational Institute of General Medical Sciences2021 to 2025$1,674,900September 1, 2019March 31, 2030MORDECAI, ERINreporter.nih.gov
ImmunoPET Probes for the Imaging of Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,674,600September 19, 2023July 31, 2028ZEGLIS, BRIAN MATTHEWreporter.nih.gov
Rickettsial Influence on Host Membrane Physiology in Arthropod VectorsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,664,045August 25, 2021July 31, 2026SWALE, DANIELreporter.nih.gov
Emergence of tick borne encephalitis in North AmericaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,660,767December 12, 2018November 30, 2025TELFORD, SAM Rreporter.nih.gov
Immunomodulatory mechanisms of wild bird reservoir hosts that facilitate persistence of Lyme disease bacteriaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,654,992March 25, 2024January 31, 2029LIN, YI-PINreporter.nih.gov
Modulation of Host Cell Responses by Francisella tularensisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,648,413June 10, 2019May 31, 2026THANASSI, DAVID Greporter.nih.gov
Bacterial and host factors in the pathogenesis of Lyme neuroborreliosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,636,050June 23, 2022April 30, 2027BRISSETTE, CATHERINE AYNreporter.nih.gov
Neuroimaging and blood markers in post treatment Lyme disease with persistent neurologic symptomsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,630,195September 20, 2023August 31, 2028MARVEL, CHERIE Lreporter.nih.gov
Translation of a highly protective tularemia vaccine to the NHP modelNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,612,445January 15, 2024November 30, 2028HAZLETT, KARSTEN R.O.reporter.nih.gov
Ehrlichia Notch SLiM-activated oncoprotein inhibition of apoptosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,600,000November 1, 2021October 31, 2026MCBRIDE, JERE Wreporter.nih.gov
Molecular Genetics of Lyme ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,567,371January 15, 2020November 30, 2025WEIS, JANIS J.reporter.nih.gov
Treating flaviviruses with mRNA-encoded Cas13NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,562,785June 13, 2024May 31, 2029SANTANGELO, PHILIP Jreporter.nih.gov
Keys to prevent iron hijacking and infection by intracellular bacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,560,000February 1, 2020January 31, 2026RIKIHISA, YASUKOreporter.nih.gov
Host Factors Controlling Neuroinvasive Flavivirus PathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,555,000August 5, 2022July 31, 2026LAZEAR, HELENreporter.nih.gov
Genetic basis for persistence of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,547,485September 20, 2023August 31, 2028TOKARZ, RAFALreporter.nih.gov
Understanding the proviral role for TRAF6 interaction with the viral protease in flavivirus replication and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,545,000May 15, 2020April 30, 2025TAYLOR, ROGER TRAVISreporter.nih.gov
Mechanisms of Age Dependent Powassan Virus NeurovirulenceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,486,022December 12, 2023October 31, 2028MACKOW, ERICH Rreporter.nih.gov
Delineation of unique flagellar proteins in spirochetesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,479,778February 23, 2024December 31, 2028MOTALEB, MD Areporter.nih.gov
Murine TyphusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,453,516September 1, 1982May 31, 2025RAHMAN, MOHAMMED SAYEEDURreporter.nih.gov
Powassan virus evolution, fitness, and pathogenesis in the Northeast and Midwest United StatesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,449,322July 1, 2024June 30, 2029ALIOTA, MATTHEW Treporter.nih.gov
CNS Senescence and Immunopathology in Lethal POWV Infection of Aged MiceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,444,052August 16, 2024July 31, 2029MACKOW, ERICH Rreporter.nih.gov
Regulatory Network of the Lyme Disease PathogenNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,426,161July 1, 2009May 31, 2028YANG, X. FRANKreporter.nih.gov
Disease transmission along complex human-animal networks: a novel method for improving zoonotic disease modelingNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,403,023September 17, 2024August 31, 2029MEISNER, JULIANNEreporter.nih.gov
An antigen-detection assay to diagnose Babesia microti infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,384,164January 10, 2018May 31, 2024LEDIZET, MICHELreporter.nih.gov
Borrelia burgdorferi mitogen in development of arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,372,498April 1, 1993December 31, 2025WEIS, JANIS J.reporter.nih.gov
Isolation of broadly protective monoclonal antibodies for Crimean Congo Hemorrhagic FeverNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,356,263July 1, 2025June 30, 2029SAJADI, MOHAMMAD MOHSENIreporter.nih.gov
Arthropod exosomes mediate vector-pathogen interactionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,311,708August 19, 2019July 31, 2026SULTANA, HAMEEDAreporter.nih.gov
Redox Regulation of DksA-dependent Borrelia burgdorferi infectivityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,277,811August 1, 2023July 31, 2027BOURRET, TRAVIS Jreporter.nih.gov
Chimeric epitope based vaccines for tick borne infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,255,844July 24, 2019June 30, 2024MARCONI, RICHARD Treporter.nih.gov
Vaccines Against Ehrlichia and Anaplasma Species InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,244,930June 1, 2020December 31, 2022GANTA, ROMAN R.reporter.nih.gov
Malaria and Mosquito/Tick-borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,232,416July 1, 2019July 31, 2030SULLIVAN, DAVID JOSEPHreporter.nih.gov
Vaccines Against Ehrlichia and Anaplasma Species InfectionsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,197,652June 1, 2020May 31, 2026GANTA, ROMAN R.reporter.nih.gov
SCH: Machine LEarning & MicrofluiDics for Multimodal Sensing of TiCk-bOrne Diseases(MEDICO)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,194,187September 13, 2022August 31, 2027SRIVASTAVA, SOUMYA Kreporter.nih.gov
RpoS Regulation of Borrelia burgdorferi Genes in vivoNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,187,520April 1, 1990August 31, 2024RADOLF, JUSTIN Dreporter.nih.gov
Reverse-engineering a viral Swiss army knife: Crimean-Congo hemorrhagic fever virus glycoprotein functions in assembly, entry, and in vivo pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,144,171August 15, 2024July 31, 2029CHANDRAN, KARTIKreporter.nih.gov
Development of Paratransgenic Ticks for Disease ControlNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,106,078July 1, 2002November 30, 2024MUNDERLOH, ULRIKE GERTRUDreporter.nih.gov
Preclinical Development of Human Monoclonal Antibodies for Postexposure Treatment of Crimean-Congo Hemorrhagic FeverNIHNational Institute of Allergy and Infectious Diseases2021$1,104,705June 1, 2017May 31, 2023GEISBERT, THOMAS WILLIAMreporter.nih.gov
Phage-mediated horizontal gene transfer in Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,101,178July 25, 2024June 30, 2029SECOR, PATRICK Rreporter.nih.gov
Anaplasma Phagocytophilum Modulate Tick Gene Expression for its Survival and Transmission from the Vector HostNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,077,124July 18, 2017June 30, 2029NEELAKANTA, GIRISHreporter.nih.gov
Genetics and Axenic Growth of tick-borne E. chaffeensis and A. phagocytophilumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,073,482July 15, 2024May 31, 2029GANTA, ROMAN R.reporter.nih.gov
The natural release of unusual peptidoglycan fragments drives persistent Lyme disease symptoms in susceptible hostsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,073,058June 15, 2023May 31, 2028JUTRAS, BRANDON LYONreporter.nih.gov
Vector and Host Contributions to the Regulation of E. Chaffeensis Gene ExpressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,072,622December 15, 2007December 31, 2022GANTA, ROMAN R.reporter.nih.gov
Defining the host and pathogen determinants of peptidoglycan induced pathophysiology in Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,053,949August 1, 2024July 31, 2027JUTRAS, BRANDON LYONreporter.nih.gov
Molecular Basis of CD1D and Natural Killer T Cell FunctionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,026,763August 19, 2019July 31, 2024JOYCE, SEBASTIANreporter.nih.gov
Arkansas Center for Food Allergy Research (ArCOFAR)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$979,787March 14, 2024February 28, 2031JONES, STACIE Mreporter.nih.gov
Phylogeographic dynamics of tick-borne pathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$935,188June 1, 2020May 31, 2025BRISSON, DUSTINreporter.nih.gov
Determination of the genetic basis for B. burgdorferi mammalian infectivityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$931,524June 1, 2013May 31, 2025JEWETT, MOLLIE Wreporter.nih.gov
Development of a vaccination platform for emerging flavivirus infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$919,536November 4, 2021October 31, 2026BECKHAM, JOHN DAVIDreporter.nih.gov
Regulation of glycerol utilization in Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$877,496June 8, 2018May 31, 2024SAMUELS, D. SCOTTreporter.nih.gov
Cross-Protective Multivalent Vaccine for Tick-Borne FlavivirusesNIHNational Institute of Allergy and Infectious Diseases2021$876,712April 6, 2015July 31, 2023CLEMENTS, DAVID Ereporter.nih.gov
Parasite-Derived Vesicles in Babesia virulence and Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2024$874,372August 1, 2024July 31, 2025BEN MAMOUN, CHOUKRIreporter.nih.gov
Development of a vaccination platform for emerging flavivirus infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$873,046November 4, 2021June 30, 2023BECKHAM, JOHN DAVIDreporter.nih.gov
Pathogenesis of Borrelia miyamotoi infection and Lyme coinfection in miceNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$837,500December 1, 2017November 30, 2022BOCKENSTEDT, LINDA K.reporter.nih.gov
Mechanisms of viral RNA maturation by co-opting cellular exonucleasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$833,933June 1, 2022April 30, 2023KIEFT, JEFFREY Sreporter.nih.gov
Characterization of innate immune signaling pathways in the tick Ixodes scapularisNIHNational Institute of Allergy and Infectious Diseases2025$831,622March 1, 2025February 28, 2030PERRIMON, NORBERTreporter.nih.gov
At the site of the bite: Immune Response to tick-transmitted RickettsiaeNIHNational Institute of Allergy and Infectious Diseases2025$824,955February 1, 2025January 31, 2030VARELA-STOKES, ANDREA SOARESreporter.nih.gov
A role for glycolipids and unconventional T cell subsets in alpha-gal allergyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$796,034June 17, 2020May 31, 2026IWEALA, ONYINYE Ireporter.nih.gov
Control of bacterial infections by a horizontally acquired host peptidoglycan amidaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$795,640January 14, 2019December 31, 2022PANNING, BARBARAreporter.nih.gov
Identification of essential factors contributing to vector colonization and transmission of relapsing fever spirochetesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$792,500March 1, 2018February 29, 2024LOPEZ, JOB Ereporter.nih.gov
Interactions of tick-borne pathogens, Borrelia burgdorferi and Babesia microti with the mammalian host using rodent model of co-infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$785,000August 9, 2019July 31, 2025PARVEEN, NIKHATreporter.nih.gov
Functional and Mechanistic Studies of the Role of Lp17-encoded Factors in Host Adaptation by the Lyme Disease SpirocheteNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$765,000July 12, 2024June 30, 2029BANKHEAD, TROY MICHAELreporter.nih.gov
Rocky Mountain Spotted Fever Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$760,029September 1, 2021December 31, 2022GANTA, ROMAN R.reporter.nih.gov
Molecular details of the IgE antibody response to galactose-alpha-1,3-galactose in alpha-gal syndromeNIHNational Institute of Allergy and Infectious Diseases2025$753,304March 1, 2025February 28, 2026SMITH, SCOTT ALANreporter.nih.gov
Deciphering innate and adaptive immune responses to Rickettsia parkeriNIHNational Institute of Allergy and Infectious Diseases2025$745,295June 20, 2025May 31, 2030BURKE, THOMAS Preporter.nih.gov
Identification of GP38 and NP antibodies and their protective mechanisms against CCHFVNIHNational Institute of Allergy and Infectious Diseases2025$738,880September 3, 2025August 31, 2030PEGAN, SCOTT DUSANreporter.nih.gov
Outer Membrane Proteins of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$736,700January 1, 2005December 31, 2023AKINS, DARRIN R.reporter.nih.gov
Use of forward Genetic approaches to identify Babesia receptorsNIHNational Heart, Lung, and Blood Institute2021$710,081December 15, 2017November 30, 2022LOBO, CHERYL ANNreporter.nih.gov
Antibody-mediated immunity to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$673,407March 8, 2021October 1, 2022BAUMGARTH, NICOLEreporter.nih.gov
Coping with Stress: Next Generation Approaches to Borrelia burgdorferi Host AdaptationNIHNational Institute of Allergy and Infectious Diseases2021$661,519April 1, 2017March 31, 2023HU, LINDEN Treporter.nih.gov
Deciphering Borrelia burgdorferi RpoS regulatory networks in ticks and mammalsNIHNational Institute of Allergy and Infectious Diseases2025$640,129September 1, 2025August 31, 2030CAIMANO, MELISSA Jreporter.nih.gov
Developing a Potent Broad-Spectrum Prophylactic for Tickborne DiseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$600,000July 17, 2024June 30, 2027WYCOFF, KEITHreporter.nih.gov
A novel therapeutic for Lyme arthritis based on a secretory leukocyte protease inhibitorNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$599,866July 8, 2024June 30, 2027FIKRIG, EROLreporter.nih.gov
A therapeutic for Lyme disease based on Peptidoglycan Recognition Protein 1NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$599,028August 4, 2021July 31, 2024NARASIMHAN, SUKANYAreporter.nih.gov
A Multivalent mRNA Vaccine to Prevent Transmission of Tick-bornePathogensNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$597,612May 1, 2024April 30, 2027NARASIMHAN, SUKANYAreporter.nih.gov
Factor H-Fc Fusion as a Pre-Exposure Prophylactic for Rickettsia InfectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$595,353July 10, 2024June 30, 2027WYCOFF, KEITHreporter.nih.gov
Virulence Mechanisms of Multifunctional Borrelial ProteinsNIHNational Institute of Allergy and Infectious Diseases2024$594,545June 15, 2020May 31, 2026GARCIA, BRANDON LEEreporter.nih.gov
Low-cost Production of a Vaccine for Lyme Disease in MaizeNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$593,524March 2, 2021February 29, 2024EGELKROUT, ERINreporter.nih.gov
The Ecology and Classification of Rickettsia Species Phylotype G022, an Uncharacterized Bacterium from Ixodes pacificus TicksNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$590,000September 12, 2022August 31, 2027ZHONG, JIANMINreporter.nih.gov
Bioinspired mechanogating biosensors for real-time biodetectionNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$577,400March 1, 2022November 30, 2025YAO, JUNreporter.nih.gov
Generation and characterization of a large-scale transposon mutant library of Rickettsia parkeriNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$569,472January 2, 2024December 31, 2026GOLEY, ERIN Dreporter.nih.gov
The natural release of unusual peptidoglycan fragments drives persistent Lyme disease symptoms in susceptible hostsNIHNational Institute of Allergy and Infectious Diseases2023$561,872June 15, 2023June 15, 2024JUTRAS, BRANDON LYONreporter.nih.gov
Transposon mutagenesis of Rickettsia for studying Rickettsia-host-vector interactionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$558,250January 1, 2024December 31, 2026KIM, HWAN KEUNreporter.nih.gov
Vector and Host Contributions to the Regulation of E. chaffeensis GeneNIHNational Institute of Allergy and Infectious Diseases2023$545,563December 15, 2007June 30, 2026GANTA, ROMAN R.reporter.nih.gov
Novel Bacterial Small RNAs as Determinants of Rickettsial Virulence and TransmissionNIHNational Institute of Allergy and Infectious Diseases2021$540,869June 13, 2018May 31, 2024NARRA, HEMA PRASADreporter.nih.gov
Reversible transformation of Anaplasma phagocytophilum using Cre-Lox recombinationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$538,112January 1, 2024December 31, 2026OLIVER, JONATHAN Dreporter.nih.gov
Development of recombinant VSV vaccines for emerging bunyavirusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$532,169April 13, 2023March 31, 2026BATES, PAULreporter.nih.gov
Tool development for Anaplasma phagocytophilum to understand determinants of infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$527,564January 1, 2024December 31, 2026BRAYTON, KELLY ANNreporter.nih.gov
Ehrlichia modulation of RNA splicing to influence KIRREL1-regulated Hippo signalingNIHNational Institute of Allergy and Infectious Diseases2025$520,128August 1, 2025July 31, 2030MCBRIDE, JERE Wreporter.nih.gov
A cross-species signaling system in tick immunity and developmentNIHNational Institute of Allergy and Infectious Diseases2025$518,099July 17, 2025June 30, 2030PAL, UTPALreporter.nih.gov
Defining the host and pathogen determinants of peptidoglycan induced pathophysiology in Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2023$512,455August 2, 2023July 31, 2024JUTRAS, BRANDON LYONreporter.nih.gov
Global Gene Expression Responses of Francisella tularensis to intracellular Infection of Human Alveolar MacrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$512,020March 25, 2021February 28, 2025SKERRETT, SHAWN J.reporter.nih.gov
Global virulence regulatory network in the Lyme disease pathogenNIHNational Institute of Allergy and Infectious Diseases2025$509,130January 2, 2025December 31, 2029OUYANG, ZHIMINGreporter.nih.gov
Rickettsial influence on host membrane physiology in arthropod vectorsNIHNational Institute of Allergy and Infectious Diseases2021$508,647August 25, 2021July 31, 2022SWALE, DANIELreporter.nih.gov
Borrelia burgdorferi-Induced Autoimmunity in Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021$503,943June 1, 2013December 31, 2022STEERE, ALLEN Creporter.nih.gov
Microbial Determinants of Clinical Heterogeneity in Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$499,998July 24, 2020July 31, 2024LEMIEUX, JACOB ERICreporter.nih.gov
Understanding the Molecular Determinants of Reassortment in Orthobunyaviruses and Phleboviruses.NIHNational Institute of Allergy and Infectious Diseases2022 to 2023$498,000September 2, 2020June 30, 2025TILSTON-LUNEL, NATASHA LOUISEreporter.nih.gov
Repression of inflammasome by Francisella tularensisNIHNational Institute of Allergy and Infectious Diseases2024$480,000July 16, 2013August 31, 2027MALIK, MEENAKSHIreporter.nih.gov
Establishing CRISPR cell screening for the deer tick Ixodes scapularis, a vector of Lyme and other diseasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$468,950August 18, 2022July 31, 2024PERRIMON, NORBERTreporter.nih.gov
Identification of host factors required by the tick-borne Powassan virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$466,125November 23, 2020October 31, 2023RICE, CHARLES Mreporter.nih.gov
Identifying the Target of a Potent and Selective Inhibitor of Babesia Blood Stages.NIHNational Institute of Allergy and Infectious Diseases2022 to 2023$466,125July 7, 2022June 30, 2025KAFSACK, BJORN FELIX CAESARreporter.nih.gov
Ribosome structure determination from Apicomplexan parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$466,125May 24, 2023April 30, 2025LEGER-ABRAHAM, MELISSAreporter.nih.gov
Pre-clinical studies to repurpose FDA-approved adenosine A2A receptor antagonists for lethal rickettsial infectionNIHNational Institute of Allergy and Infectious Diseases2025$463,698June 11, 2025May 31, 2030GONG, BINreporter.nih.gov
Microfluidic Assays for Probing Neutrophil-Borrelia Interactions in Blood during Acute Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$462,000April 1, 2021March 31, 2024IRIMIA, DANIELreporter.nih.gov
Eliciting and isolating neutralizing antibodies against Powassan virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$462,000August 1, 2021July 31, 2023LAI, JONATHAN R.reporter.nih.gov
The Role the AAA+ Lon Proteases in Bacterial PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021$461,823June 1, 2017May 31, 2024KARZAI, A. WALIreporter.nih.gov
Systematic identification of interactions between Lyme Borrelia and Ixodes scapularisNIHNational Institute of Allergy and Infectious Diseases2025$461,375July 1, 2025June 30, 2027FIKRIG, EROLreporter.nih.gov
Immunophenotypic analysis of the cutaneous humoral response in early Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$460,625February 3, 2022January 31, 2024BOCKENSTEDT, LINDA K.reporter.nih.gov
Contribution of RpoS to persistence of Borrelia burgdorferi in mammalsNIHNational Institute of Allergy and Infectious Diseases2025$457,875July 1, 2025June 30, 2027CAIMANO, MELISSA Jreporter.nih.gov
Elucidating the contributions of c-di-GMP and PlzA to tick- and mammalian host-adaptation in Lyme disease spirochetesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$456,886June 1, 2023May 31, 2026CAIMANO, MELISSA Jreporter.nih.gov
Investigating unknown yet essential mechanisms of gene regulation for tick-borne relapsing fever spirochetes.NIHNational Institute of Allergy and Infectious Diseases2025$454,791August 22, 2025July 31, 2027LOPEZ, JOB Ereporter.nih.gov
Identification of the agent of Southern Tick Associated Rash IllnessNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$445,500March 8, 2021August 31, 2023TOKARZ, RAFALreporter.nih.gov
Investigation of the prevalence, presentation and immunologic features of the α-Gal syndrome in a high-risk cohort not recruited on the basis of allergic diseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$444,125July 22, 2022June 30, 2025WILSON, JEFFREY Mreporter.nih.gov
PLURIPOTENCY OF NOVEL TICK CYSTEINE PROTEASE INHIBITORS DURING HEMATOPHAGYNIHNational Institute of Allergy and Infectious Diseases2022$444,000July 20, 2022June 30, 2026MORGAN, SARAH Ereporter.nih.gov
Development of a novel multipurpose model to propagate and study the tick transmission cycle of relapsing fever spirochetes from Eurasia.NIHNational Institute of Allergy and Infectious Diseases2023 to 2024$441,375July 5, 2023June 30, 2025LOPEZ, JOB Ereporter.nih.gov
Delineating adaptive mechanisms of tick-borne relapsing fever spirochetes within the argasid vector.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$441,375November 21, 2023October 31, 2026LOPEZ, JOB Ereporter.nih.gov
Detecting released peptidoglycan fragments as a biomarker for direct diagnosis of acute and chronic Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$440,941March 11, 2021February 29, 2024JUTRAS, BRANDON LYONreporter.nih.gov
Infection and prevalence of a new segmented flavivirus in the United StatesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$440,038April 13, 2021March 31, 2023KAPOOR, AMITreporter.nih.gov
Rickettsial CspA proteins and host microRNAs in exosome formation and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2025$440,000August 1, 2025July 31, 2027SOONG, LYNNreporter.nih.gov
Mechanisms by which rickettsiae subvert autophagy pathway in macrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$439,750August 4, 2021July 31, 2024FANG, RONG MEGANreporter.nih.gov
The role of RNA deletion and duplication events in Powassan virus pathogenesis and evolutionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$439,550February 24, 2023January 31, 2026PIANTADOSI, ANNE Lreporter.nih.gov
Spatial eco-epidemiology of tick-borne rickettisal pathogensNIHNational Institute of Allergy and Infectious Diseases2021$439,081August 18, 2017July 31, 2024GAFF, HOLLYreporter.nih.gov
Identification of stage-and tissue-specific endogenous tick promotersNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$439,000August 1, 2023July 31, 2025GULIA-NUSS, MONIKAreporter.nih.gov
Activation of T gamma/delta cells by Borrelia glycolipidsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$438,625June 4, 2021May 31, 2024BENACH, JORGE L.reporter.nih.gov
Protease sensor for rapid and sensitive detection of Borrelia infectionsNIHNational Institute of Allergy and Infectious Diseases2025$436,236August 1, 2025July 31, 2027BOGYO, MATTHEWreporter.nih.gov
The Role of YebC in persistent infection of the Lyme disease pathogenNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$435,875May 16, 2022April 30, 2025YANG, X. FRANKreporter.nih.gov
Innate Immune Regulation of Powassan Virus NeurovirulenceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$435,263July 1, 2024October 31, 2026MACKOW, ERICH Rreporter.nih.gov
Characterizing the Pan-genome of a Rickettsia Infecting the Eastern Black-legged TickNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$435,228January 22, 2021December 31, 2022GILLESPIE, JOSEPH Jreporter.nih.gov
Defining the roles of an enhancer long non-coding RNA eIncRNA-ID2 in rickettsial pathogenesis and immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$434,500January 4, 2021December 31, 2024SAHNI, ABHAreporter.nih.gov
Quantitative analysis of growth in a streamlined obligate intracellular pathogenNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$434,375March 1, 2021February 29, 2024GOLEY, ERIN Dreporter.nih.gov
Basic immunological toolbox for genus Peromsycus, infection tolerant reservoirs of zoonotic agentsNIHNational Institute of Allergy and Infectious Diseases2025$431,750July 1, 2025June 30, 2027BARBOUR, ALAN G.reporter.nih.gov
In vitro culture of Babesia microtiNIHNational Institute of Allergy and Infectious Diseases2025$431,143January 23, 2025December 31, 2027TELFORD, SAM Rreporter.nih.gov
Effect of Borrelia burgdorferi-SIRPalpha Interaction on the Immune ResponseNIHNational Institute of Allergy and Infectious Diseases2025$429,000July 17, 2025June 30, 2027COBURN, JENIFER Lreporter.nih.gov
Integrating population genomics and microbial metagenomics of the lone star tick, an expanding arthropod disease vectorNIHNational Institute of Allergy and Infectious Diseases2022$428,341August 1, 2022July 31, 2025MONZON, JAVIERreporter.nih.gov
Subversion of Keratinocyte Function by a Tick Salivary ProteinNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$427,625February 16, 2024December 31, 2025PEDRA, JOAOreporter.nih.gov
Designing a Robust Platform for the In vitro Propagation of Babesia Microti in Human RBCsNIHNational Institute of Allergy and Infectious Diseases2025$427,000December 13, 2024November 30, 2027LOBO, CHERYL ANNreporter.nih.gov
Role of Borrelia Lpt Homologs in Surface Lipoprotein SecretionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$426,250June 23, 2023May 31, 2026ZUECKERT, WOLFRAM Rreporter.nih.gov
Host-pathogen-vector interactions of R. amblyommatis for spotted fever pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$425,173April 15, 2022March 31, 2025KIM, HWAN KEUNreporter.nih.gov
Redefining the Interaction Between Extracellular Immune Mechanisms and Intracellular Rickettsia InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$424,875May 25, 2021April 30, 2024RILEY, SEAN PHILLIPreporter.nih.gov
Regulation of Skin Immunity by a Tick BiteNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$424,875November 1, 2021October 31, 2024PEDRA, JOAOreporter.nih.gov
Virulent Rickettsia species utilize the CD300f phosphatidylserine-binding receptor on macrophages for host colonization and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$424,875August 1, 2022July 31, 2025VOSS, OLIVERreporter.nih.gov
Investigating Rickettsia Interspecies and Host-Specific Lipopolysaccharide VariationNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$424,875June 1, 2022May 31, 2025GILLESPIE, JOSEPH Jreporter.nih.gov
Cyclic di-GMP Second Messenger Signaling in the Tickborne Relapsing Fever Spirochete, Borrelia turicataeNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$423,883March 25, 2021February 28, 2025BLEVINS, JON SCOTTreporter.nih.gov
Evaluating the Ability of the Invasive Asian Longhorned Tick, Haemaphysalis longicornis, to Maintain and Transmit North American Tick-borne VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$423,500August 4, 2021July 31, 2024HERMANCE, MEGHAN ELIZABETHreporter.nih.gov
Exploiting the arthropod vector: novel mechanisms of Mycobacterium leprae transmissionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$423,500November 28, 2022October 31, 2025MACALUSO, KEVIN R.reporter.nih.gov
Role of Tick Metalloprotease Inhibitors in the Transmission of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2025$423,106August 1, 2025July 31, 2027MULENGA, ALBERTreporter.nih.gov
Demonstrating the mechanism of Nairovirus translation strategyNIHNational Institute of Allergy and Infectious Diseases2021$423,000August 1, 2021July 31, 2025MIR, MOHAMMAD Areporter.nih.gov
The mechanism and role of erythrocyte invasion by Francisella tularensisNIHNational Heart, Lung, and Blood Institute2023$421,500May 1, 2019July 31, 2026HORZEMPA, JOSEPH Areporter.nih.gov
Mechanistic and Functional Analysis of a Putative Regulatory Factor in the Lyme Disease SpirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$420,750December 9, 2020November 30, 2023BANKHEAD, TROY MICHAELreporter.nih.gov
Functional and Mechanistic Studies of the VlsE-mediated Immune Avoidance System in the Lyme Disease SpirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$420,750March 13, 2021February 29, 2024BANKHEAD, TROY MICHAELreporter.nih.gov
Exploratory Studies of lp17-encoded Genetic Factors Important for Tick Colonization by the Lyme Disease SpirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$420,750March 16, 2021February 29, 2024BANKHEAD, TROY MICHAELreporter.nih.gov
Mutational Analysis of Putative Genetic Elements Required for Vmp Regulated Expression and Antigenic Variation by the Relapsing Fever Agent, Borrelia hermsiiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$420,750August 24, 2021July 31, 2024BANKHEAD, TROY MICHAELreporter.nih.gov
Zoonotic tick-borne pathogens contribute to acute febrile illness in rural South AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$420,426March 18, 2019February 28, 2025OOSTHUIZEN, MARINDA CATHARINAreporter.nih.gov
Development of osmoregulation disruptors for tick controlNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$418,000June 16, 2021May 31, 2023PARK, YOONSEONGreporter.nih.gov
Adaptation of an in vitro generated human skin model for tick feeding to study Borrelia burgdorferi transmission and colonizationNIHNational Institute of Allergy and Infectious Diseases2025$417,845August 1, 2025July 31, 2027BRINKWORTH, AMANDA J.reporter.nih.gov
Host Ca2+, actin, and ATP production in rickettsia-endothelial cell dysfunctionNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$417,621July 5, 2022June 30, 2024DUMLER, JOHN STEPHENreporter.nih.gov
A novel antimicrobial resistance mechanism for Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$416,625August 1, 2022July 31, 2025SKARE, JON Treporter.nih.gov
Enrichment and validation of urine and serum-specific antigens from acute Lyme disease patient samplesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$416,448December 10, 2021November 30, 2024AUCOIN, DAVID Preporter.nih.gov
A murine model of Lyme neuroborreliosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$414,292July 1, 2024June 30, 2027ROGOVSKY, ARTEM Sreporter.nih.gov
Pathogen-host interactions in Lyme disease interrogated at Single Cell LevelNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$412,500April 8, 2021March 31, 2024SESHU, JANAKIRAMreporter.nih.gov
Immune Modulation During Acute Lyme Disease Infection as the Result of Aberrant Immunoglobulin GlycosylationNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$411,941August 16, 2023July 31, 2025COMUNALE, MARY ANNreporter.nih.gov
Analysis of the DksA regulon in the Lyme disease spirocheteNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$411,125March 19, 2021February 29, 2024OUYANG, ZHIMINGreporter.nih.gov
Characterization of vsp/vlp system of Borrelia recurrentisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$409,748July 5, 2024June 30, 2027ROGOVSKY, ARTEM Sreporter.nih.gov
Elucidating the Bacterial and Host Mechanisms Governing B. burgdorferi-Related Type I Interferon ResponsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$408,694September 15, 2021August 31, 2025HYDE, JENNY A.reporter.nih.gov
The roles of Anaplasma phagocytophilum surface proteins in infectionNIHNational Institute of Allergy and Infectious Diseases2021$408,604July 15, 2007June 30, 2022CARLYON, JASON Areporter.nih.gov
Retrotransposon assay for tick host bloodmeal identificationNIHNational Institute of Allergy and Infectious Diseases2021$407,800August 6, 2018July 31, 2023TELFORD, SAM Rreporter.nih.gov
The Role of Hemocytes in tick Rickettsia parkeri infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$407,000December 1, 2023October 31, 2026KARIM, SHAHIDreporter.nih.gov
Impacts of Borrelia burgdorferi Gac protein on infectivity and regulation of virulence protein expressionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$405,746June 1, 2024April 30, 2027STEVENSON, BRIANreporter.nih.gov
TICK DETERMINANTS OF POWASSAN VIRUS TRANSMISSIONNIHNational Institute of Allergy and Infectious Diseases2021$405,000May 1, 2019April 30, 2023THANGAMANI, SARAVANANreporter.nih.gov
Immune response to inhalation of live attenuated vaccine in an outbred tularemia model (Resubmission)NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$404,818January 6, 2021December 31, 2024REED, DOUGLAS SCOTTreporter.nih.gov
Identification of Genetic Markers of Susceptibility to Intracellular Bacterial Infection Using the Collaborative Cross Mouse ModelNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$387,137August 1, 2022July 31, 2025BERGMANNLEITNER, ELKEreporter.nih.gov
Exploring Tr1-regulated transcription networks underpinning adaptation of pathogenic Anaplasma to the tick hostNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$378,568July 1, 2023June 30, 2025PARK, JASON MICHAELreporter.nih.gov
Identifying novel tick attractants and repellents by exploiting their olfactory and eco-physiologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$378,500June 7, 2021May 31, 2025SYED, ZAINULABEUDDINreporter.nih.gov
Mechanisms of Reverse Transendothelial Migration in Arthritis ResolutionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$366,797September 24, 2024August 31, 2026BROWN, CHARLES R.reporter.nih.gov
Clinical and viral genomic approaches to evaluate the emergence of Powassan virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$360,788January 16, 2019December 31, 2022PIANTADOSI, ANNE Lreporter.nih.gov
Morphological and molecular identification of Hyalomma tick vectors of Crimean-Congo Hemorrhagic Fever virusNIHNational Institute of Allergy and Infectious Diseases2025$355,000June 1, 2025May 31, 2028APANASKEVICH, DMITRY Areporter.nih.gov
I-Corps: Optical design and the development of high accuracy automated tick classification using computer visionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$350,705April 18, 2022June 30, 2022GOODWIN, AUTUMNreporter.nih.gov
A Single-Dose Long-Lasting Live-Attenuated Chimeric Vaccine Candidate Against the Emerging Tick-Borne Kyasanur Forest DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$344,093August 15, 2025July 31, 2030LEE, YOUNG-MINreporter.nih.gov
Machine learning-based development of serologic test for acute Lyme disease diagnosisNIHNational Institute of Allergy and Infectious Diseases2021$300,000June 4, 2021May 31, 2022KELBAUSKAS, LAIMONASreporter.nih.gov
Low-dose RNA vaccine platform for tickborne flavivirusesNIHNational Institute of Allergy and Infectious Diseases2022$300,000June 15, 2022October 31, 2024MANDL, CHRISTIAN W.reporter.nih.gov
Antibody isotyping for discrimination of disease stage and diagnosis of early Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2021$295,514July 1, 2020March 31, 2023GOMES-SOLECKI, MARIAreporter.nih.gov
A Point of Care Test for Babesia microtiNIHNational Institute of Allergy and Infectious Diseases2025$293,142September 21, 2025August 31, 2027SUTHERLAND, ALAN GORDONreporter.nih.gov
A viral vector-based vaccine to induce humoral and cellular immune protection against Powassan virus in a tick transmission modelNIHNational Institute of Allergy and Infectious Diseases2025$281,786September 23, 2025August 31, 2027MARIN LOPEZ, ALEJANDROreporter.nih.gov
Highly-sensitive, rapid and low cost plasmonic assay platform for Lyme disease diagnosisNIHNational Institute of Allergy and Infectious Diseases2022$259,613August 12, 2022July 31, 2024GUIGNON, ERNEST FITCHreporter.nih.gov
mRNA vaccination targeting Amblyomma ticks to prevent alpha gal syndromeNIHNational Institute of Allergy and Infectious Diseases2025$251,250February 1, 2025January 31, 2027NARASIMHAN, SUKANYAreporter.nih.gov
Host heterogeneity affects susceptibility of Babesia microti infection using vector-mediated transmissionNIHNational Institute of Allergy and Infectious Diseases2025$250,573March 1, 2025February 28, 2027TUFTS, DANIELLE Mreporter.nih.gov
Understanding the Role of Tick Phospholipase A2 in Alpha-Gal SyndromeNIHNational Institute of Allergy and Infectious Diseases2025$235,822July 23, 2025June 30, 2027KARIM, SHAHIDreporter.nih.gov
A PET Radiotracer for Diagnostic and Theranostics Imaging in Lyme DiseaseNIHNational Institute of Biomedical Imaging and Bioengineering2021$234,000June 1, 2020March 31, 2022ZEGLIS, BRIAN MATTHEWreporter.nih.gov
Investigating putative antimicrobial product biosynthesis in a tick endosymbiont.NIHNational Institute of Allergy and Infectious Diseases2025$232,500November 14, 2024October 31, 2026CULL, BENJAMINreporter.nih.gov
T4SS effectors and tick tropism in Anaplasma phagocytoliumNIHNational Institute of Allergy and Infectious Diseases2021$229,500June 1, 2020May 31, 2023BRAYTON, KELLY ANNreporter.nih.gov
Microbial genetic variation in the pathogenesis of Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021$226,948March 1, 2020February 28, 2024LIN, YI-PINreporter.nih.gov
Defining human xenoglycan-specific B cellsNIHNational Institute of Allergy and Infectious Diseases2025$225,953July 22, 2025June 30, 2027GUTHMILLER, JENNAreporter.nih.gov
Lyme disease spirochete adhesion to tick cellsNIHNational Institute of Allergy and Infectious Diseases2021$225,000February 18, 2020January 31, 2024RENTHAL, ROBERT Dreporter.nih.gov
Exploring the Collaborative Cross resource to identify different phenotypes of Lyme neuroborreliosis and disease-contributing genetic factorsNIHNational Institute of Allergy and Infectious Diseases2023$223,105September 1, 2023May 31, 2024ROGOVSKY, ARTEM Sreporter.nih.gov
Powassan virus nanobodies from camelid monomeric variable antibody domains elicited by natural infectionNIHNational Institute of Allergy and Infectious Diseases2021$211,875June 15, 2020May 31, 2022MACDONALD, MARGARET Rreporter.nih.gov
Borrelia miyamotoi meningioencephalitisNIHNational Institute of Allergy and Infectious Diseases2021$211,500January 1, 2020December 31, 2022BRISSETTE, CATHERINE AYNreporter.nih.gov
Investigating genes of unknown function required for Rickettsia parkeri infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$210,082August 15, 2022August 14, 2025SIT, BRANDON YIU CHUNGreporter.nih.gov
mRNA-Based Vaccines Against Tick Borne ThogotovirusesNIHNational Institute of Allergy and Infectious Diseases2025$207,262March 1, 2025February 28, 2027BOON, ADRIANUS CMreporter.nih.gov
Early Host Responses During Co-Infection of Tick-Borne PathogensNIHNational Institute of Allergy and Infectious Diseases2021$205,469June 30, 2020May 31, 2023MACNAMARA, KATHERINE C.reporter.nih.gov
A VSV vectored vaccine for emergent tick-born phlebovirusesNIHNational Institute of Allergy and Infectious Diseases2021$202,917March 2, 2020February 28, 2023BATES, PAULreporter.nih.gov
Skin-associated B cells in allergyNIHNational Institute of Allergy and Infectious Diseases2021$201,875February 1, 2020July 31, 2022ERICKSON, LOREN Dreporter.nih.gov
Challenging the generalist paradigm: Leveraging tick chemical ecology for new control methodsNIHNational Institute of Allergy and Infectious Diseases2021$200,625September 11, 2020August 31, 2023MACHTINGER, ERIKA Treporter.nih.gov
Identification of the mechanism of protection against a B. burgdorferi protein CspZ for the prevention of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021$199,455February 1, 2020January 31, 2024LIN, YI-PINreporter.nih.gov
Developing comparative chemical genomics and genetic validation tools for Babesia spp.NIHNational Institute of Allergy and Infectious Diseases2021$199,375June 12, 2020May 31, 2022DURAISINGH, MANOJ Treporter.nih.gov
Functional Impact of Stress Granules on Tick-Microbe InteractionsNIHNational Institute of Allergy and Infectious Diseases2021$198,798June 9, 2020May 31, 2022SHAW, DANA KATHLEENreporter.nih.gov
Role of mTOR signaling in endothelial responses to Rickettsia rickettsii infection.NIHNational Institute of Allergy and Infectious Diseases2021$197,500February 4, 2020January 31, 2023SAHNI, ABHAreporter.nih.gov
Targeting extracellular tRNA-derived RNA fragments (tRFs) to protect against fatal rickettsiosisNIHNational Institute of Allergy and Infectious Diseases2021$197,500June 23, 2020May 31, 2024GONG, BINreporter.nih.gov
Ehrlichia TRP120 HECT E3 ubiquitin ligase modulation of host cell pathwaysNIHNational Institute of Allergy and Infectious Diseases2021$197,500September 1, 2020August 31, 2023MCBRIDE, JERE Wreporter.nih.gov
Bourbon virus: Therapy development and SerologyNIHNational Institute of Allergy and Infectious Diseases2021$196,875March 13, 2020February 28, 2023BOON, ADRIANUS CMreporter.nih.gov
Advancement of a Mucosal Subunit Vaccine in an Outbred Model of Respiratory TularemiaNIHNational Institute of Allergy and Infectious Diseases2021$195,082February 18, 2020July 31, 2023BAKSHI, CHANDRA SHEKHARreporter.nih.gov
Structural Elucidation of the Novel RNA Polymerase Underlying Francisella Tularensis VirulenceNIHNational Institute of Allergy and Infectious Diseases2021$194,778February 1, 2020January 31, 2022BRENNAN, RICHARD GERALDreporter.nih.gov
Spatial case-control studies to target the human ecology of tick-borne infectionsNIHNational Institute of Allergy and Infectious Diseases2021$194,029June 10, 2020May 31, 2024LOVER, ANDREW Areporter.nih.gov
Molecular basis of Wnt activation by Ehrlichia Wnt ligand mimicsNIHNational Institute of Allergy and Infectious Diseases2021$193,422March 1, 2020February 28, 2023MCBRIDE, JERE Wreporter.nih.gov
MHC class II presentation of Borrelia burgdorferi and synovial tissue antigens in murine Lyme arthritisNIHNational Institute of Allergy and Infectious Diseases2021$192,500January 17, 2020December 31, 2022LOCHHEAD, ROBERTreporter.nih.gov
Mechanisms of central nervous system invasion by the Lyme disease spirochete, Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2025$192,500April 8, 2025March 31, 2027CASSELLI, TIMOTHYreporter.nih.gov
Anaplasma phagocytophilum modulates the type IV secretion system pilus to achieve tick transmissionNIHNational Institute of Allergy and Infectious Diseases2021$191,250February 20, 2020January 31, 2023BRAYTON, KELLY ANNreporter.nih.gov
Mechanistic Studies of the Role of Genetic Factors in VlsE Antigenic Variation by the Lyme Disease SpirocheteNIHNational Institute of Allergy and Infectious Diseases2025$191,250January 1, 2025December 31, 2026BANKHEAD, TROY MICHAELreporter.nih.gov
Molecular basis for anaphylaxis due to galactose-alpha-1,3-galactose (alpha-gal)NIHNational Institute of Allergy and Infectious Diseases2021$187,027June 2, 2020May 31, 2024SMITH, SCOTT ALANreporter.nih.gov
Evaluation of zoonotic reservoir hosts for severe fever with thrombocytopenia syndrome virusNIHNational Institute of Allergy and Infectious Diseases2021$184,423May 22, 2020April 30, 2024BOSCO-LAUTH, ANGELA MARIAHreporter.nih.gov
Regulation of infection-associated protein expressed by the Lyme disease spirochete DnaA proteinNIHNational Institute of Allergy and Infectious Diseases2021$184,332February 14, 2020January 31, 2024STEVENSON, BRIANreporter.nih.gov
FH-Fc as a Pre-Exposure Prophylactic for Tickborne DiseaseNIHNational Institute of Allergy and Infectious Diseases2021$181,737July 17, 2020June 30, 2022WYCOFF, KEITHreporter.nih.gov
Targeting a ubiquitous spirochete bacteriophage to prevent Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021$181,250March 10, 2020February 28, 2022SECOR, PATRICK Rreporter.nih.gov
Evaluation of tafenoquine for prophylaxis of babesiosis caused by Babesia microtiNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$178,000February 17, 2023January 31, 2026VANNIER, EDOUARD Greporter.nih.gov
Exploring the Collaborative Cross resource to identify different phenotypes of Lyme neuroborreliosis and disease-contributing genetic factorsNIHNational Institute of Allergy and Infectious Diseases2024$177,351September 1, 2024August 31, 2025ROGOVSKY, ARTEM Sreporter.nih.gov
Characterization of Francisella tularensis-specific bacteriophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$176,875April 1, 2021March 31, 2024BAKSHI, CHANDRA SHEKHARreporter.nih.gov
Novel application of isoxazoline veterinary drugs to streamline reservoir-targeted abatement of tick-borne zoonosesNIHNational Institute of Allergy and Infectious Diseases2021$174,610September 1, 2020August 31, 2023VAUGHAN, JEFFERSON ARCHERreporter.nih.gov
Synovium Immunoprivilege and the Modulation of Resident Synovial Macrophage Functions in Lyme ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$167,076May 15, 2025April 30, 2030CYNDARI, KAREN Ireporter.nih.gov
Development of an improved transposon mutagenesis system for comprehensive genetic analysis of Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2025$165,000July 1, 2025June 30, 2027CAMILLI, ANDREWreporter.nih.gov
First detection of rickettsiae in a US chigger population and the potential risk to peopleNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$162,839November 1, 2021April 30, 2024PONNUSAMY, LOGANATHANreporter.nih.gov
EGF as an environmental cue of B. burgdorferi gene regulationNIHNational Institute of Allergy and Infectious Diseases2025$162,000May 5, 2025April 30, 2027HART, THOMASreporter.nih.gov
Determining the vector ecology and epidemiology of tick-borne spotted fever group Rickettsia in a large urban setting of Houston, TX.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$160,500February 24, 2021January 31, 2024GUNTER, SARAH MURPHYreporter.nih.gov
Developing a tick-borne Rickettsia isolate library.NIHNational Institute of Allergy and Infectious Diseases2025$160,500August 1, 2025July 31, 2027GUNTER, SARAH MURPHYreporter.nih.gov
A small RNA regulation of virulence in Lyme disease pathogenNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$154,500September 1, 2021August 31, 2023YANG, XIULIreporter.nih.gov
Efferocytosis in Lyme Arthritis ResolutionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$151,930February 14, 2020June 30, 2022BROWN, CHARLES R.reporter.nih.gov
Testing Borrelia recurrentis isolates by using a newly developed louse-borne relapsing fever mouse modelNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$151,500July 9, 2021June 30, 2024ROGOVSKY, ARTEM Sreporter.nih.gov
Anaplasma phagocytophilum exploitation of regulated exocytosis.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$148,460May 25, 2024May 24, 2027CHIARELLI, TRAVIS JOSEPHreporter.nih.gov
Evaluating Effect of Woody Plant Encroachment on Tick-borne Pathogens in the South Central United StatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$145,314January 20, 2022December 31, 2024NODEN, BRUCE HOWARDreporter.nih.gov
Phage-mediated horizontal gene transfer in Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2024$144,559July 25, 2024August 9, 2024SECOR, PATRICK Rreporter.nih.gov
Identifying Determinants of Borrelia burgdorferi and Peromyscus leucopus symbiosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$143,365August 1, 2023August 2, 2025BOURGEOIS, JEFFREYreporter.nih.gov
Isothermal Titration CalorimeterNIHOffice of the Director, National Institutes of Health2024$143,119July 15, 2024April 15, 2025HUGHES, TRAVIS SHANEreporter.nih.gov
Identification of linear plasmid lp36-encoded virulence determinants in the Lyme disease spirochete Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$141,000November 1, 2021October 31, 2024CASSELLI, TIMOTHYreporter.nih.gov
Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitisNIHNational Institute of Allergy and Infectious Diseases2021$137,898September 1, 2021November 30, 2021GARRO, ARIS Creporter.nih.gov
Microbial Determinants of Clinical Heterogeneity in Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021$136,350July 24, 2020June 30, 2022LEMIEUX, JACOB ERICreporter.nih.gov
Structural and Functional Alteration of host RBCs by BabesiaNIHNational Institute of Allergy and Infectious Diseases2025$134,730December 13, 2024November 30, 2026BERI, DIVYAreporter.nih.gov
Effect of Powassan virus genetic variation on replication in human cell culture and transmission by ticksNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$127,672August 1, 2021July 31, 2024MCMINN, REBEKAHreporter.nih.gov
Application of parallel PCR and DNA sequencing for detecting remnant host DNA from the prior blood meal of Ixodes scapularisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$115,424March 8, 2021February 28, 2025LANDESMAN, WILLIAMreporter.nih.gov
Understanding the Molecular Determinants of Reassortment in Orthobunyaviruses and Phleboviruses.NIHNational Institute of Allergy and Infectious Diseases2021$87,098September 2, 2020August 31, 2022TILSTON-LUNEL, NATASHA LOUISEreporter.nih.gov
Host genetic determinants of neuroinvasive flavivirus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$86,658March 1, 2022May 19, 2023JASPERSE, BRITTANYreporter.nih.gov
Infectious cell entry pathway of human-infecting thogotovirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$82,366May 1, 2021May 30, 2023ROTHLAUF, PAUL WILLIAMreporter.nih.gov
Defining the ecology of tick-borne relapsing fever Borrelia turicatae in Austin, Texas.NIHNational Institute of Allergy and Infectious Diseases2021$80,250January 1, 2020December 31, 2022LOPEZ, JOB Ereporter.nih.gov
Rab27 in tick extracellular vesicle biogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$77,316January 1, 2022November 2, 2023BUTLER, LILLIAN RAINERreporter.nih.gov
Developing a system for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttoniiNIHNational Institute of Allergy and Infectious Diseases2021$76,000February 10, 2020January 31, 2023BLEVINS, JON SCOTTreporter.nih.gov
Overlooked No More: Discovering Pathogens in a National Tick CollectionNIHNational Institute of Allergy and Infectious Diseases2021$74,800February 25, 2020January 31, 2022LITTLE, SUSAN Ereporter.nih.gov
Investigating the Genetic Determinants of Host-Specificity and Potential for Further Adaptation of Powassan VirusNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$73,455April 1, 2024March 31, 2026LANGE, RACHELreporter.nih.gov
B. burgdorferi interactions with the blood-CSF barrier: Development of a 3D choroid plexus organoidNIHNational Institute of Allergy and Infectious Diseases2025$70,500November 15, 2024October 31, 2026BRISSETTE, CATHERINE AYNreporter.nih.gov
Structure and function of the Powassan Virus 3' untranslated regionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$67,692June 1, 2021April 30, 2023SZUCS, MATTHEW Jreporter.nih.gov
SeqStudio Genetic AnalyzerNIHNational Institute of General Medical Sciences2025$64,802August 1, 2025July 31, 2026ACHATZ, TYLER JOSEPHreporter.nih.gov
Transmission of Rickettsia africae by Amblyomma americanum and AmblyommamaculatumNIHNational Institute of Allergy and Infectious Diseases2021$53,879March 10, 2020February 28, 2023MUKARATIRWA, SAMSONreporter.nih.gov
Separating the molecular determinants that govern the evolution of Orthoflavivirus NS5-mediated IFN antagonismNIHNational Institute of Allergy and Infectious Diseases2025$49,538June 1, 2025May 31, 2028BEDNARSKI, EVAreporter.nih.gov
Interferons and eosinophils promote liver injury during Ehrlichia-induced shockNIHNational Institute of Allergy and Infectious Diseases2025$49,538December 5, 2025December 4, 2027BAHR, AMBERreporter.nih.gov
Characterization of a Lipid Receptor in Tick Humoral ImmunityNIHNational Institute of Allergy and Infectious Diseases2021$40,662April 1, 2020March 31, 2022O’NEAL, ANYA JOSEPHINEreporter.nih.gov
Characterizing Notch Ligand Mimic Function of the Ehrlichia TRP120 Effector in Suppression of Host Cell ApoptosisNIHNational Institute of Allergy and Infectious Diseases2021$34,831September 1, 2020August 31, 2022PATTERSON, LANISHAreporter.nih.gov
Structural studies of virulence activation in Francisella tularensisNIHNational Institute of Allergy and Infectious Diseases2021$33,490July 1, 2020April 30, 2022TRAVIS, BRADY Areporter.nih.gov
Annual meeting of the American Society for RickettsiologyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$22,000July 5, 2024June 30, 2027GILK, STACEY Dreporter.nih.gov
Application of parallel PCR and DNA sequencing for detecting remnant host DNA from the prior blood meal of Ixodes scapularisNIHNational Institute of Allergy and Infectious Diseases2021$18,795March 8, 2021June 30, 2021LANDESMAN, WILLIAMreporter.nih.gov
Defining the impact of complement inhibition by tick saliva in tick-borne virus evolution and adaptive immune responses in murine models of infectionNIHNational Institute of Allergy and Infectious Diseases2022$13,504January 1, 2023April 1, 2023STONE, EMILY TAYLORreporter.nih.gov
31st Meeting of the American Society for RickettsiologyNIHNational Institute of Allergy and Infectious Diseases2022$8,000June 23, 2022May 31, 2023MACALUSO, KEVIN R.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Vermont & ST Agric CollegeBurlington, VT1$19.5 million0$0
Tufts University BostonBoston, MA12$16.6 million0$0
Washington UniversitySaint Louis, MO6$15 million0$0
University of Maryland BaltimoreBaltimore, MD12$14.6 million0$0
Yale UniversityNew Haven, CT9$14.3 million0$0
Virginia Commonwealth UniversityRichmond, VA8$13.4 million0$0
University of Texas Med BR GalvestonGalveston, TX15$12.4 million0$0
Health Research Incorporated/New York State Department of HealthMenands, NY2$10.8 million0$0
University of VirginiaCharlottesville, VA4$10.1 million0$0
Massachusetts Institute of TechnologyCambridge, MA4$9.7 million0$0
SUNY at Stony BrookStony Brook, NY9$9.7 million0$0
Johns Hopkins UniversityBaltimore, MD7$7.7 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH3$6.8 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC5$6.8 million0$0
Washington State UniversityPullman, WA12$6.2 million0$0
Vanderbilt University Medical CenterNashville, TN5$6.1 million0$0
University of Maryland, College ParkCollege Park, MD5$6.1 million0$0
University of MontanaMissoula, MT5$5.9 million0$0
Boston Children's HospitalBoston, MA1$5.6 million0$0
University of Missouri-ColumbiaColumbia, MO6$5.5 million0$0
Institut PasteurParis1$5.5 million0$0
Boston CollegeChestnut Hill, MA1$5.4 million0$0
University of PennsylvaniaPhiladelphia, PA4$5.4 million0$0
University of MinnesotaMinneapolis, MN5$5.4 million0$0
Indiana University IndianapolisIndianapolis, IN4$5.1 million0$0
Brandeis UniversityWaltham, MA1$5.1 million0$0
Tulane University of LouisianaNew Orleans, LA1$5 million0$0
Biopeptides, Inc.Ridgefield, CT2$5 million0$0
Duke UniversityDurham, NC3$4.3 million0$0
University of WashingtonSeattle, WA3$4.2 million0$0
Kansas State UniversityManhattan, KS5$4.1 million0$0
University of California-IrvineIrvine, CA3$4 million0$0
Helixbind, Inc.Boxborough, MA2$4 million0$0
East Carolina UniversityGreenville, NC2$3.8 million0$0
L2 Diagnostics, LLCNew Haven, CT6$3.8 million0$0
Aldatu Biosciences, Inc.Watertown, MA1$3.7 million0$0
Ohio State UniversityColumbus, OH2$3.6 million0$0
Texas A&m University Health Science CTRCollege Station, TX3$3.5 million0$0
Medical College of WisconsinMilwaukee, WI3$3.5 million0$0
Planet Biotechnology, Inc.Hayward, CA4$3.4 million0$0
Massachusetts General HospitalBoston, MA5$3.4 million0$0
Integral MolecularPhiladelphia, PA1$3.3 million0$0
Immuno Technologies, Inc.Memphis, TN2$3.3 million0$0
Vectech, LLCBaltimore, MD2$3.2 million0$0
University of KentuckyLexington, KY4$3.2 million0$0
Thomas Jefferson UniversityPhiladelphia, PA1$3.1 million0$0
University of South AlabamaMobile, AL5$3.1 million0$0
Colorado State UniversityFort Collins, CO3$3 million0$0
Design-Zyme, LLCLawrence, KS1$3 million0$0
University of UtahSalt Lake City, UT2$2.9 million0$0
University of California-BerkeleyBerkeley, CA1$2.9 million0$0
West Virginia University Research CorporationMorgantown, WV2$2.9 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR3$2.9 million0$0
Board of Regents, NSHE, obo University of Nevada, RenoReno, NV3$2.9 million0$0
University of South FloridaTampa, FL3$2.8 million0$0
Banfieldbio Inc.Woodinville, WA1$2.8 million0$0
Kephera Diagnostics, LLCFramingham, MA1$2.8 million0$0
University of Connecticut SCH of Med/dntFarmington, CT4$2.7 million0$0
Baylor College of MedicineHouston, TX7$2.5 million0$0
University of ConnecticutStorrs, CT1$2.5 million0$0
University of Texas at San AntonioSan Antonio, TX3$2.5 million0$0
University of California-RiversideRiverside, CA2$2.5 million0$0
Cornell UniversityIthaca, NY1$2.4 million0$0
University of Tennessee KnoxvilleKnoxville, TN2$2.4 million0$0
Emory UniversityAtlanta, GA3$2.4 million0$0
University of Rhode IslandKingston, RI1$2.3 million0$0
Oregon Health & Science UniversityPortland, OR1$2.3 million0$0
Virovax LLCLawrence, KS1$2.3 million0$0
Triad National Security, LLCLos Alamos, NM1$2.2 million0$0
University of South Carolina at ColumbiaColumbia, SC1$2.2 million0$0
University of IowaIowa City, IA2$2.2 million0$0
University of North Dakota Main CampusGrand Forks, ND5$2.2 million0$0
University of California Los AngelesLos Angeles, CA1$2.2 million0$0
New York Structural Biology CenterNew York, NY1$2.1 million0$0
Northwestern University at ChicagoChicago, IL2$2.1 million0$0
Stanford UniversityStanford, CA2$2.1 million0$0
University of Colorado DenverAurora, CO4$2 million0$0
Columbia University Health SciencesNew York, NY2$2 million0$0
Hunter CollegeNew York, NY2$1.9 million0$0
Arizona State UniversityScottsdale, AZ1$1.9 million0$0
Albany Medical CollegeAlbany, NY3$1.9 million0$0
Harvard Medical SchoolBoston, MA4$1.8 million0$0
University of Texas at AustinAustin, TX1$1.7 million0$0
University of FloridaGainesville, FL1$1.7 million0$0
Albert Einstein College of MedicineBronx, NY2$1.6 million0$0
University of Toledo Health Sci CampusToledo, OH1$1.5 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA3$1.5 million0$0
Creighton UniversityOmaha, NE1$1.3 million0$0
New York Blood CenterNew York, NY3$1.3 million0$0
Montana State UniversityBozeman, MT1$1.1 million0$0
University of Southern MississippiHattiesburg, MS3$1.1 million0$0
Michigan State UniversityEast Lansing, MI3$1 million0$0
Arkansas Children's Hospital Res InstLittle Rock, AR1$979,7870$0
The University of Central Florida Board of TrusteesOrlando, FL1$931,5240$0
Ut Southwestern Medical CenterDallas, TX1$919,5360$0
Hawaii Biotech, Inc.Honolulu, HI1$876,7120$0
Texas A&m Agrilife ResearchCollege Station, TX3$797,7110$0
University of California, San FranciscoSan Francisco, CA1$795,6400$0
Rbhs-New Jersey Medical SchoolNewark, NJ1$785,0000$0
University of Massachusetts AmherstAmherst, MA2$771,4290$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025155$93,168,3730$0
2024154$89,260,8460$0
2023144$76,708,4470$0
2022175$92,959,0810$0
2021176$81,343,7280$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 2 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 340 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 340 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 340 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 340 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 340 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 340 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 340 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 340 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 340 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 340 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 340 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 340 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 340 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 340 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 340 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 340 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 340 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.855May 7, 2027Not listedSame assistance listing 93.855 as 340 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.