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Data / Research funding / Stimulant Use and Misuse

Stimulant Use and Misuse: 787 NIH awards ($1.2B) to 225 organizations

787 NIH awards ($1.2B) in the NIH spending category Stimulant Use and Misuse, to 225 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 787 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
NIDA Clinical Trials Network: Big South/West Node (CTN-0132 and CTN-0139)NIHNational Institute on Drug Abuse2021 to 2025$43,417,361March 1, 2025February 28, 2032TRIVEDI, MADHUKAR H.reporter.nih.gov
The Florida Node Alliance of the National Drug Abuse Clinical Trials Network (CTN-121)NIHNational Institute on Drug Abuse2021 to 2025$26,301,696March 1, 2025February 29, 2028SZAPOCZNIK, JOSEreporter.nih.gov
NorthStar Node of the NIDA Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$22,374,119September 1, 2015February 29, 2032BART, GAVINreporter.nih.gov
The Ohio Valley Node of the Clinical Trials Network (CTN-0153)NIHNational Institute on Drug Abuse2021 to 2025$18,588,752March 1, 2025February 29, 2032WINHUSEN, T JOHNreporter.nih.gov
Single cell transcriptomic and epigenomic changes during chronic HIV infection and cocaine self-administrationNIHNational Institute on Drug Abuse2022 to 2025$14,516,969June 1, 2022March 31, 2027ZENG, HONGKUIreporter.nih.gov
OUTLAST - A First Multiple-Dose Efficacy Study of IXT-m200, an anti-METH Monoclonal Antibody, in Patients with METH Use DisorderNIHNational Institute on Drug Abuse2021 to 2023$13,778,020September 30, 2021July 31, 2025STEVENS, MISTY WARDreporter.nih.gov
Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIVNIHNational Institute on Drug Abuse2021 to 2025$12,564,620September 1, 2021June 30, 2027KELLIS, MANOLISreporter.nih.gov
AIDS Linked to the IntraVenous Experience (ALIVE) StudyNIHNational Institute on Drug Abuse2021 to 2025$12,226,379January 1, 2014May 31, 2030MEHTA, SHRUTI Hreporter.nih.gov
Clinical Development of a Therapeutic Agent for Rapid Reversal of Methamphetamine IntoxicationNIHNational Institute on Drug Abuse2023 to 2025$11,962,715August 15, 2023June 30, 2026LI, XINHUAreporter.nih.gov
IND-enabling program for a long-acting anti-methamphetamine monoclonal antibody for treating methamphetamine use disorderNIHNational Institute on Drug Abuse2022 to 2024$9,900,251September 30, 2022July 31, 2025STEVENS, MISTY WARDreporter.nih.gov
M-SCORCH: Methamphetamine use disorder data generation center for Single Cell Opioid Responses in the Context of HIVNIHNational Institute on Drug Abuse2021 to 2025$9,490,616May 15, 2021February 28, 2027HO, YA-CHIreporter.nih.gov
Development of PPL-138, a Novel Mixed NOP/Mu Partial Agonist for Treatment of CocaineUse DisorderNIHNational Institute on Drug Abuse2022 to 2024$8,683,509September 30, 2022July 31, 2025TOLL, LAWRENCE Rreporter.nih.gov
Development of a Long-acting Enzyme Therapy for Treatment of Cocaine AbuseNIHNational Institute on Drug Abuse2021 to 2022$8,242,506August 15, 2020April 30, 2026ZHAN, CHANG-GUOreporter.nih.gov
Therapeutic Agent for Rapid Reversal of Methamphetamine IntoxicationNIHNational Institute on Drug Abuse2021 to 2022$8,123,947September 30, 2020May 31, 2024LI, XINHUAreporter.nih.gov
Greater Southern California Node of the Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$7,788,993June 1, 2019February 29, 2032MOONEY, LARISSA JEANETTEreporter.nih.gov
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primatesNIHNational Institute on Drug Abuse2023 to 2025$7,434,979June 1, 2023February 29, 2028RANA, TARIQ Mreporter.nih.gov
Efficacy, safety, and pharmacokinetic study of BICX104 naltrexone subcutaneous implant alone and in combination with bupropion for the treatment of Methamphetamine Use Disorder (MUD).NIHNational Institute on Drug Abuse2024 to 2025$7,405,564March 1, 2024November 30, 2027DEVARNEY, KATHERINE BEEBEreporter.nih.gov
Cohort Studies of HIV/AIDS and Substance Use in MiamiNIHNational Institute on Drug Abuse2025$7,372,834September 30, 2025June 30, 2030BAUM, MARIANNA Kreporter.nih.gov
MSM and Substances Cohort at UCLA Linking Infections Noting Effects (MASCULINE)NIHNational Institute on Drug Abuse2021 to 2024$7,177,379September 30, 2013April 30, 2026GORBACH, PAMINA MAEreporter.nih.gov
Development of sigma receptor/DAT dual-targeting compounds to treat stimulant use disorderNIHNational Institute on Drug Abuse2023 to 2024$6,903,733August 15, 2023July 31, 2026REICH, JEFFREYreporter.nih.gov
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug TourismNIHNational Institute on Drug Abuse2021 to 2024$6,868,774April 1, 2020January 31, 2026STRATHDEE, STEFFANIE A.reporter.nih.gov
PDE7 Inhibitor for the Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$6,689,019April 15, 2023March 31, 2027GAITANARIS, GEORGEreporter.nih.gov
Characterization, optimization, and development of dual mGlu2/3 positive allosteric modulators for opioid use disorderNIHNational Institute on Drug Abuse2022$6,445,203July 15, 2022June 30, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Single Cell Transcriptomics of the Cocaine Use Disorder in the Context of HIVNIHNational Institute on Drug Abuse2022 to 2025$6,266,450June 15, 2022March 31, 2027CHENG, CHRISTINEreporter.nih.gov
Optimizing HIV prevention for high-risk methamphetamine-using men who have sex with menNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,855,396April 8, 2022April 30, 2027GROV, CHRISTIANreporter.nih.gov
Effects of HIV, Cocaine, and Prolonged ART Use on Subclinical Cardiovascular DiseaseNIHNational Institute on Drug Abuse2021 to 2024$5,744,264June 1, 2016April 30, 2025LAI, SHENGHANreporter.nih.gov
Clinical Trials Network: Pacific Northwest Node (CTN-0082, -0131, -0139 and dissemination library)NIHNational Institute on Drug Abuse2021 to 2025$5,664,540March 1, 2025February 29, 2032HATCH, MARY AKIKOreporter.nih.gov
Meth-OD: A PHASE 2A STUDY OF IXT-M200 IN METHAMPHETAMINE OVERDOSE PATIENTSNIHNational Institute on Drug Abuse2021 to 2022$5,613,312September 30, 2020June 30, 2024STEVENS, MISTY WARDreporter.nih.gov
Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSNIHNational Institute on Drug Abuse2021 to 2024$5,321,290March 1, 2015April 30, 2026HAYASHI, KANNAreporter.nih.gov
TMP-301, A Negative Allosteric Modulator of type 5 metabotropic glutamate receptors (mGluR5), for Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2022 to 2023$5,310,920September 1, 2022August 31, 2025MEYERS, CHARLES DANIELreporter.nih.gov
Optimization and testing of anti-methamphetamine antibody therapy to support pivotal clinical trials and commercializationNIHNational Institute on Drug Abuse2021 to 2022$5,281,643May 1, 2020February 29, 2024STEVENS, MISTY WARDreporter.nih.gov
Development of TNX-1300 (Double Mutant Cocaine Esterase) for the Treatment of Life-Threatening Cocaine IntoxicationNIHNational Institute on Drug Abuse2022 to 2025$5,181,674August 1, 2022November 30, 2025SULLIVAN, GREGORY Mreporter.nih.gov
Modeling drugs of abuse-HIV interactions using iPSC-derived human cerebral organoidsNIHNational Institute on Drug Abuse2021 to 2025$4,890,555September 30, 2021July 31, 2026SANNA, PIETRO Preporter.nih.gov
Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and StimulantNIHNational Institute on Drug Abuse2022 to 2025$4,732,000April 1, 2022February 28, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
Single nucleus gene expression in moderate and compulsive drug self-administration in a rodent model of HIVNIHNational Institute on Drug Abuse2022 to 2025$4,653,858March 15, 2022November 30, 2026SANNA, PIETRO Preporter.nih.gov
Optimizing HIV prevention for highly vulnerable methamphetamine-using sexual minority menNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$4,518,889April 8, 2022April 30, 2024GROV, CHRISTIANreporter.nih.gov
Discovery of Addiction-Related Genes with Advanced Mouse ResourcesNIHNational Institute on Drug Abuse2021 to 2025$4,405,786April 1, 2015May 31, 2027CHESLER, ELISSA Jreporter.nih.gov
Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brainNIHNational Institute on Drug Abuse2021 to 2025$4,310,228April 1, 2021February 28, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
Establishment and Characterization of Novel Mutant Mouse Models for the Addiction Research CommunityNIHNational Institute on Drug Abuse2021 to 2025$4,218,988August 15, 2021May 31, 2027KUMAR, VIVEKreporter.nih.gov
Evaluating Assessment and Medication Treatment of ADHD in Children with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$4,182,561May 1, 2024August 31, 2025ESBENSEN, ANNA J.reporter.nih.gov
Identification of Genetic Variants that Contribute to Compulsive Cocaine Intakein RatsNIHNational Institute on Drug Abuse2021 to 2025$3,976,898April 1, 2017June 30, 2027GEORGE, OLIVIERreporter.nih.gov
Early Life Stress, Chronic Drug Use and Neuroplasticity in Nonhuman Primate Models of Cocaine Abuse: Relevance to Treatment StrategiesNIHNational Institute on Drug Abuse2021 to 2025$3,974,079April 1, 2021January 31, 2027SANCHEZ, MAR Mreporter.nih.gov
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseNIHNational Institute on Drug Abuse2021 to 2025$3,865,844September 25, 2022January 31, 2029OWENS, DOUGLAS Kreporter.nih.gov
Spatio-temporal Methods for Surveillance of the Opioid SyndemicNIHNational Institute on Drug Abuse2021 to 2025$3,748,657September 1, 2025August 31, 2029KLINE, DAVID Mreporter.nih.gov
The Comparative Effectiveness and Safety of Pharmacotherapies for the Treatment of Opioid Use Disorder in PregnancyNIHNational Institute on Drug Abuse2021 to 2025$3,680,536April 1, 2020May 31, 2029HUYBRECHTS, KRISTA Freporter.nih.gov
Case-Control Study of Methamphetamine in Pulmonary Arterial HypertensionNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,677,031August 20, 2021May 31, 2027KAWUT, STEVEN Mreporter.nih.gov
Understanding neuronal subtype-specific function of NAc in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2025$3,661,419April 1, 2021February 28, 2026ZHANG, YIreporter.nih.gov
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C UCB J PET StudyNIHNational Institute on Drug Abuse2021 to 2025$3,657,020July 1, 2021April 30, 2027ANGARITA, GUSTAVO ADOLFOreporter.nih.gov
Structure and Function of Dopamine ReceptorsNIHNational Institute of Mental Health2021 to 2025$3,613,300September 1, 1995April 30, 2027JAVITCH, JONATHAN Areporter.nih.gov
Small molecule modulators of ΔFosBNIHNational Institute on Drug Abuse2021 to 2025$3,586,553July 1, 2016March 31, 2027RUDENKO, GABRIELLEreporter.nih.gov
PTPRD Phosphatase inhibitors for stimulant use disordersNIHNational Institute on Drug Abuse2022 to 2024$3,540,141July 1, 2022June 30, 2025UHL, GEORGE RICHARDreporter.nih.gov
Synthetics in Combination (SYNC)NIHNational Institute on Drug Abuse2021 to 2025$3,536,582September 30, 2021June 30, 2026CICCARONE, DANIEL Hreporter.nih.gov
Allosteric Modulators of Dopamine Transporter as Therapeutic Agents for NeuroAIDSNIHNational Institute on Drug Abuse2021 to 2024$3,446,099July 1, 2020April 30, 2026AUGELLI-SZAFRAN, CORINNE ELIZABETHreporter.nih.gov
Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural AreaNIHNational Institute on Drug Abuse2022 to 2025$3,434,019September 30, 2022August 31, 2027MAGIDSON, JESSICA Freporter.nih.gov
Secondhand Harms from Alcohol & Drugs: Impacts on Families and Communities across the USNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,368,295September 20, 2021June 30, 2027KERR, WILLIAM C.reporter.nih.gov
Epigenetic mechanisms of sustained transcription across cocaine abstinenceNIHNational Institute on Drug Abuse2021 to 2025$3,351,544July 1, 2021May 31, 2026HELLER, ELIZABETH Areporter.nih.gov
Promoting remote and secondary risk prevention services in rural settingsNIHNational Institute on Drug Abuse2022 to 2025$3,349,340September 30, 2022July 31, 2027PHO, MAI TUYETreporter.nih.gov
Drug development of clavulanic acid, a GLT-1 activator: proof of concept for cocaine use disorderNIHNational Institute on Drug Abuse2022 to 2023$3,340,215May 15, 2020December 31, 2024MORRISON, MARY F.reporter.nih.gov
Project Nurture Expansion StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,304,098September 24, 2021August 31, 2026COHEN, DEBORAH JILLreporter.nih.gov
IND-enabling studies and phase I clinical trials to advance CD74-target, DRhQ, as a treatment for stimulant use disorderNIHNational Institute on Drug Abuse2025$3,287,052May 15, 2025April 30, 2027SHIRLEY, RENEE LYNNreporter.nih.gov
PRIME: PrEP Intervention for people who Inject MEthamphetamineNIHNational Institute on Drug Abuse2021 to 2024$3,225,418August 1, 2020June 30, 2026COFFIN, PHILLIP Oreporter.nih.gov
Neurocognitive Abnormalities in Stimulant Abuse among High-Risk WomenNIHNational Institute on Drug Abuse2022 to 2025$3,207,045August 1, 2022May 31, 2027KIEHL, KENT Areporter.nih.gov
Genetics of novelty seeking and propensity for drug abuse in outbred ratsNIHNational Institute on Drug Abuse2021 to 2025$3,193,903September 1, 2023June 30, 2028AKIL, HUDAreporter.nih.gov
Cocaine use, viral suppression and precursors of stroke in HIV infectionNIHNational Institute on Drug Abuse2021 to 2024$3,185,105June 1, 2020April 30, 2026RILEY, ELISE D.reporter.nih.gov
Development of a first-in-class nonmuscle myosin II inhibitor to prevent substance use disorder relapseNIHNational Institute on Drug Abuse2021 to 2023$3,182,913September 30, 2021August 31, 2024YOUNG, ERICA Jreporter.nih.gov
A DUAL CHIMERIC HUMAN ASTROGLIAL-MICROGLIAL MODEL OF HIV AND HANDNIHNational Institute on Drug Abuse2021 to 2025$3,125,946August 1, 2021May 31, 2026GOLDMAN, STEVEN ALANreporter.nih.gov
Contingency management plus deep transcranial magnetic stimulation for the treatment of cocaine use disorderNIHNational Institute on Drug Abuse2025$3,119,619September 15, 2025June 30, 2029SCHMITZ, JOY MARIEreporter.nih.gov
Preferences and predictors driving opioid-involved polysubstance use profiles and trajectories: Implications for improving careNIHNational Institute on Drug Abuse2022 to 2025$3,119,296September 30, 2022August 31, 2027COUGHLIN, LARA NICOLEreporter.nih.gov
PET Imaging of neurochemical transmission in cocaine use disordersNIHNational Institute on Drug Abuse2021 to 2025$3,096,100September 30, 2009June 30, 2027NARENDRAN, RAJESHreporter.nih.gov
Mechanisms Mediating Cocaine Abuse in Socially Housed Female and Male MonkeysNIHNational Institute on Drug Abuse2021 to 2025$3,072,958September 1, 2001May 31, 2029NADER, MICHAEL Areporter.nih.gov
cART, neuroHIV, cocaine abuse and the mPFC neuron/astrocyte dysfunctionNIHNational Institute on Drug Abuse2022 to 2025$3,070,264September 15, 2022August 31, 2027HU, XIU-TIreporter.nih.gov
The short and long-term dynamics of opioid/stimulant use: Mixed methods to inform overdose prevention and treatment related to polysubstance useNIHNational Institute on Drug Abuse2022 to 2025$3,051,259September 30, 2022July 31, 2027GENBERG, BECKY LYNNreporter.nih.gov
Treating Polysubstance Use in Methadone Maintenance: Application of Novel Digital TechnologyNIHNational Institute on Drug Abuse2022 to 2025$3,027,776September 30, 2022July 31, 2027ALEXANDER, KARENreporter.nih.gov
Atherosclerosis in cocaine addiction: imaging risk with PET/MRNIHNational Institute on Drug Abuse2022 to 2025$3,015,410June 1, 2022March 31, 2027ALIA-KLEIN, NELLYreporter.nih.gov
AIM(2)ing at the inflammasome: Impact of MAVS signaling in cocaine-and HIV-1 induced neuroinflammationNIHNational Institute on Drug Abuse2021 to 2025$3,004,104March 15, 2021February 28, 2027CISNEROS, IRMAreporter.nih.gov
Disrupting Social Risk Factors of Health to Improve Substance Use and Mental Health Outcomes for Parents in Rural RegionsNIHNational Institute on Drug Abuse2022 to 2025$3,001,349September 1, 2023August 31, 2027SALDANA, LISAreporter.nih.gov
reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)NIHNational Institute on Drug Abuse2022 to 2025$2,978,902September 1, 2022July 31, 2028SZAPOCZNIK, JOSEreporter.nih.gov
Molecular Studies of Cocaine Action in BrainNIHNational Institute on Drug Abuse2021 to 2025$2,971,622August 1, 1991January 31, 2026NESTLER, ERIC J.reporter.nih.gov
Role of GRIN2 in ART and SUD associated neurological deficits.NIHNational Institute on Drug Abuse2022 to 2025$2,965,829September 15, 2022August 31, 2027DASH, CHANDRAVANUreporter.nih.gov
The Development and Evaluation of Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR)NIHNational Institute on Drug Abuse2022 to 2024$2,923,597July 1, 2023June 30, 2025NWAOKOBIA, CHARLES CHIEDUreporter.nih.gov
Opioid and SUD Data Enclave (O-SUDDEn): Bringing real-time data to the opioid crisisNIHNational Institute on Drug Abuse2022 to 2025$2,921,106September 30, 2022August 31, 2027FERNANDEZ, SOLEDAD Areporter.nih.gov
D1 and D2 Dopaminoceptive Ensembles in Limbic Brain Regions in Drug AddictionNIHNational Institute on Drug Abuse2021 to 2025$2,909,999September 1, 2000April 30, 2030NESTLER, ERIC J.reporter.nih.gov
Assessing the Reach, Effectiveness, and Implementation of Multiple InterventionsNIHNational Institute on Drug Abuse2022 to 2025$2,900,711September 30, 2022July 31, 2027KRAL, ALEXANDER Hreporter.nih.gov
COINSTAC 2.0: decentralized, scalable analysis of loosely coupled dataNIHNational Institute on Drug Abuse2021 to 2024$2,856,703July 1, 2015June 30, 2026CALHOUN, VINCE Dreporter.nih.gov
Reelin Signaling and Function in Cocaine ResponseNIHNational Institute on Drug Abuse2021 to 2025$2,847,900July 1, 2021April 30, 2027DAY, JEREMY Jreporter.nih.gov
The Role of the Dopamine Transporter in Psychostimulant AbuseNIHNational Institute on Drug Abuse2021 to 2025$2,835,033July 1, 2014November 30, 2026GALLI, AURELIOreporter.nih.gov
Integrated Safety Optimization Services for People Who Use Drugs In Targeted Areas Of High Overdose RatesNIHNational Institute on Drug Abuse2022 to 2025$2,833,774September 30, 2022August 31, 2027JORDAN, AYANAreporter.nih.gov
An Experimental Medicine Approach for the Mechanistic Understanding of Cocaine Use Disorder: Reinforcer PathologyNIHNational Institute on Drug Abuse2022 to 2025$2,821,784July 15, 2022April 30, 2027LACONTE, STEPHEN Mreporter.nih.gov
In Vivo Characterization of 5-HT7 Modulators in Rat Models of Cocaine Use DisorderNIHNational Institute on Drug Abuse2022 to 2024$2,820,000June 1, 2022May 31, 2026PIPPIN, DOUGLAS ANTHONYreporter.nih.gov
Exploring Influences on Methamphetamine Use Among Males in GeorgiaNIHNational Institute on Drug Abuse2022 to 2025$2,785,741June 1, 2022March 31, 2027HUSSEN, SOPHIA A.reporter.nih.gov
Drug abuse and HIV-associated pulmonary vascular injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,784,947February 1, 2021December 31, 2025DHILLON, NAVNEET KAURreporter.nih.gov
Gene Network Identification and Integration (GNetii) Approach to Understanding the Biology Underlying HIV and Drug Abuse.NIHNational Institute on Drug Abuse2021 to 2024$2,762,265August 1, 2020May 31, 2026JOHNSON, ERIC OTTOreporter.nih.gov
Sex differences in the neural correlates underlying impairments in response inhibition and salience attribution in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2024$2,749,037April 1, 2020February 28, 2025GOLDSTEIN, RITA Zreporter.nih.gov
Peer Engagement in Methamphetamine Harm-Reduction with Contingency Management (PEER-CM)NIHNational Institute on Drug Abuse2022 to 2025$2,732,822September 30, 2022July 31, 2027KORTHUIS, PHILIP TODDreporter.nih.gov
Altered Midbrain GABAergic Circuitry Drives Greater Cocaine Self-administrationNIHNational Institute on Drug Abuse2021 to 2025$2,670,057May 15, 2021February 28, 2026DANI, JOHN A.reporter.nih.gov
A Longitudinal Qualitative Study of Fentanyl-Stimulant Polysubstance Use Among People Experiencing Homelessness (Administrative supplement)NIHNational Institute on Drug Abuse2022 to 2023$2,661,063November 1, 2023September 29, 2025MCNEIL, RYANreporter.nih.gov
Epigenetic mechanisms in the medial habenula governing drug-seeking behaviorNIHNational Institute on Drug Abuse2021 to 2024$2,638,720July 15, 2020April 30, 2026WOOD, MARCELO ANDRESreporter.nih.gov
Leveraging data synthesis to identify optimal and robust strategies for HIV elimination among substance-using MSMNIHNational Institute on Drug Abuse2022 to 2025$2,637,647May 1, 2022February 28, 2027JANULIS, PATRICK FRANCISreporter.nih.gov
Cocaine-induced mitochondrial mechanisms and molecular mediators in reward circuitryNIHNational Institute on Drug Abuse2021 to 2025$2,612,514September 15, 2014June 30, 2027LOBO, MARY KAYreporter.nih.gov
Varieties of Impulsivity in Opiate and Stimulant UsersNIHNational Institute on Drug Abuse2021 to 2025$2,598,683July 15, 2008May 31, 2027VASSILEVA, JASMIN Lreporter.nih.gov
Role of Gadd45b in Cocaine-driven Epigenetic and Behavioral DynamicsNIHNational Institute on Drug Abuse2022 to 2025$2,581,972May 1, 2022March 31, 2027DAY, JEREMY Jreporter.nih.gov
Laboratories for Early Clinical Evaluation of Pharmacotherapies for Substance Use DisordersNIHNational Institute on Drug Abuse2021 to 2024$2,568,075May 1, 2020January 31, 2026MOELLER, FREDERICK GERARDreporter.nih.gov
A Clinical Laboratory with Integrated Neuroscience (CLIN) for Early Evaluation of Medications for Substance Use DisordersNIHNational Institute on Drug Abuse2021 to 2024$2,557,655May 1, 2020January 31, 2026KAMPMAN, KYLE MATTHEWreporter.nih.gov
Examining the Skeletal Effects of PsychostimulantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,545,386August 20, 2020June 30, 2026CALARGE, CHADI A.reporter.nih.gov
Cross platform analysis of drug targets and toxicity of bath saltsNIHNational Institute on Drug Abuse2022 to 2025$2,538,810September 15, 2022June 30, 2027SCHIEFER, ISAAC Treporter.nih.gov
Methamphetamine Effect on HIV PersistenceNIHNational Institute on Drug Abuse2021 to 2024$2,535,677July 1, 2020May 31, 2025KAUL, MARCUSreporter.nih.gov
Kappa Opioid Receptors and Phospho-Dopamine Transporters Drive Cocaine RewardNIHNational Institute on Drug Abuse2022 to 2025$2,532,199September 15, 2022June 30, 2027RAMAMOORTHY, SAMMANDAreporter.nih.gov
Novel Therapeutic Agents to Reverse Opioid OverdoseNIHNational Institute on Drug Abuse2021 to 2022$2,529,335September 30, 2020August 31, 2025LI, XINHUAreporter.nih.gov
CASCADE: A North Carolina cohort to address the cascading effects of the HIV and substance use syndemicNIHNational Institute on Drug Abuse2025$2,528,513September 1, 2025July 31, 2030MEADE, CHRISTINA Sreporter.nih.gov
Genomic profiling mediating the protective effect of social reward on opioid cravingNIHNational Institute on Drug Abuse2022 to 2025$2,512,064August 1, 2022June 30, 2027VENNIRO, MARCOreporter.nih.gov
HIV, Methamphetamine and Human iPSC-derived Microglia-containing Cerebral OrganoidsNIHNational Institute on Drug Abuse2021 to 2024$2,470,488July 1, 2020April 30, 2026HO, WENZHEreporter.nih.gov
Genetics of Cocaine Sensitivity in DrosophilaNIHNational Institute on Drug Abuse2021 to 2025$2,469,830September 15, 2017April 30, 2027MACKAY, TRUDY F.reporter.nih.gov
Taking Our Shot: Extended-Release Naltrexone as Opioid Overdose Pre-Exposure Prophylaxis (PrEP) in People Using Stimulants Living With or At Risk of HIVNIHNational Institute on Drug Abuse2024$2,460,000July 1, 2024June 30, 2028APPA, AYESHA Areporter.nih.gov
Novel Dopaminergic Stimulant Prodrug for the Treatment of Apathy in ADNIHNational Institute on Aging2021 to 2022$2,458,641July 1, 2022March 31, 2024PATIL, SANDEEPreporter.nih.gov
Parvalbumin interneurons regulate nucleus accumbens synapses and behaviorNIHNational Institute on Drug Abuse2021 to 2025$2,435,138September 1, 2016May 31, 2026GRUETER, BRAD ALANreporter.nih.gov
MEDICATION DISCOVERY USING RAT MODELS OF RELAPSE. PERIOD OF PERFORMANCE: 7/10/2019-7/9/2024. N01DA-19-8949NIHNational Institute on Drug Abuse2022 to 2023$2,430,107July 10, 2019July 9, 2024SHELTON, KEITHreporter.nih.gov
Mechanisms of dopaminergic dysfunction in substance use disorderNIHNational Institute on Drug Abuse2021 to 2025$2,425,095September 30, 2021July 31, 2026CALIPARI, ERINreporter.nih.gov
Breaking bonds in prairie volesNIHNational Institute of Mental Health2022 to 2025$2,413,644March 1, 2022December 31, 2026KABBAJ, MOHAMEDreporter.nih.gov
Modeling HIV and methamphetamine-induced neuroinflammation in cerebral organoidsNIHNational Institute on Drug Abuse2022 to 2025$2,395,254September 1, 2022July 31, 2027SPEARMAN, PAUL W.reporter.nih.gov
New targeted BDNF nanoparticles for treatment of METH addiction and neurotoxicityNIHNational Institute on Drug Abuse2021 to 2022$2,378,918September 1, 2021August 31, 2025VITALIANO, FRANCOreporter.nih.gov
Methamphetamine and Other Substance Use Disorder Genetics in ThailandNIHNational Institute on Drug Abuse2023 to 2025$2,375,708June 15, 2015April 30, 2028GELERNTER, JOELreporter.nih.gov
Regulation of HIV latency by microglial-neuronal interactionsNIHNational Institute on Drug Abuse2021 to 2023$2,363,459September 15, 2019July 31, 2025KARN, JONATHANreporter.nih.gov
Investigating the molecular mechanisms of HIV/AIDS associated neurological disorders using microglia and cerebral organoids derived from induced pluripotent stem cellsNIHNational Institute on Drug Abuse2021 to 2023$2,348,133September 1, 2019July 31, 2025RANA, TARIQ Mreporter.nih.gov
Examining the Impact of the Twin Epidemics of Methamphetamine and Opioid Use on Overdose, Risky Sex and Treatment Engagement among PWUD in Two Rural Appalachian CohortsNIHNational Institute on Drug Abuse2021 to 2024$2,345,140September 1, 2012March 31, 2028HAVENS, JENNIFER Rreporter.nih.gov
In Vivo Imaging and Post-Mortem Study of Methamphetamine Use on Immune Dysfunction and HIV Reservoir Transcription among People with HIV on ARTNIHNational Institute on Drug Abuse2025$2,331,737July 15, 2025May 31, 2030HENRICH, TIMOTHY JENSENreporter.nih.gov
Neighborhood conditions, neural circuits, and substance use behaviors across the early life course.NIHNational Institute on Drug Abuse2025$2,314,254September 30, 2025June 30, 2029BARR, PETER BRENDANreporter.nih.gov
Unraveling the intersection of substance use, inflammation, and HIV via hair levelsNIHNational Institute on Drug Abuse2023 to 2025$2,283,571July 1, 2023May 31, 2028GANDHI, MONICAreporter.nih.gov
Computational modeling to evaluate interventions for HIV and substance useNIHNational Institute on Drug Abuse2023 to 2025$2,266,145September 30, 2023July 31, 2028HOTTON, ANNAreporter.nih.gov
Impact of prescription stimulants on the drug overdose epidemicNIHNational Institute on Drug Abuse2023 to 2025$2,253,245May 1, 2023March 31, 2028DE NADAI, ALESSANDRO STEVENSreporter.nih.gov
The Rhode Island Young Adult Prescription and Illicit Drug Study (RAPIDS): Responding to Fentanyl and Associated HarmsNIHNational Institute on Drug Abuse2021 to 2023$2,243,163August 15, 2019May 31, 2025MARSHALL, BRANDON DAVID LEWISreporter.nih.gov
Synthetic Psychoactive "Bath Salt" Effects on Brain Activity and BehaviorNIHNational Institute on Drug Abuse2021 to 2023$2,232,449April 15, 2019February 28, 2025KOHUT, STEPHEN JOHNreporter.nih.gov
Autophagic regulation of cocaine abuseNIHNational Institute on Drug Abuse2022 to 2025$2,222,317August 15, 2022May 31, 2027HE, CONGCONGreporter.nih.gov
Development of Brain Organoids to Study the Impact of HIV-1, Drugs of Abuse and Aging on Cognitive ImpairmentNIHNational Institute on Drug Abuse2021 to 2024$2,208,551July 15, 2020May 2, 2024NIXON, DOUGLAS Freporter.nih.gov
Ghrelin Deacylase as a Treatment for Opioid Polysubstance AbuseNIHNational Institute on Drug Abuse2022 to 2025$2,207,625July 1, 2022June 30, 2027ZHAN, CHANG-GUOreporter.nih.gov
Glial-mediated synaptic remodeling in drug addictionNIHNational Institute on Drug Abuse2022 to 2025$2,202,322June 1, 2016April 30, 2027DONG, YANreporter.nih.gov
Assessment of metformin for restoration of immune homeostasis in HIV+ and HIV- individuals with a history of injection drug useNIHNational Institute on Drug Abuse2024 to 2025$2,193,459September 30, 2024May 31, 2029KOBIE, JAMES Jreporter.nih.gov
Circadian Rhythms and Cocaine Use DisorderNIHNational Institute on Drug Abuse2021 to 2025$2,173,145August 1, 2021May 31, 2026FERRIS, MARK Jreporter.nih.gov
High-throughput Identification of Non-hallucinogenic Psychoplastogens for Treating AddictionNIHNational Institute on Drug Abuse2022 to 2025$2,172,679May 15, 2022February 28, 2027OLSON, DAVID Ereporter.nih.gov
Myosin II regulation of actin dynamics and the selective vulnerability of methamphetamine- and opioid-associated memoryNIHNational Institute on Drug Abuse2022 to 2024$2,164,851December 15, 2019November 30, 2025MILLER, COURTNEY Areporter.nih.gov
The Dopamine Synapse and Associative LearningNIHNational Institute on Drug Abuse2021 to 2025$2,161,538July 1, 1991December 31, 2028SULZER, DAVIDreporter.nih.gov
Investigate Host Gene Isoforms Contributing to HIV Persistence in Cocaine UsersNIHNational Institute on Drug Abuse2023 to 2025$2,161,166September 30, 2023July 31, 2028ZHU, JIANreporter.nih.gov
Cocaine, Parvalbumin, and Perineuronal NetsNIHNational Institute on Drug Abuse2023 to 2025$2,155,184April 1, 2023January 31, 2028SORG, BARBARA Areporter.nih.gov
5-HT2 Receptor Allosterism in Cocaine Use DisorderNIHNational Institute on Drug Abuse2022 to 2025$2,154,204August 1, 2015April 30, 2027ZHOU, JIAreporter.nih.gov
Optimizing PrEP adherence in sexual minority men who use stimulantsNIHNational Institute on Drug Abuse2021 to 2022$2,152,006July 1, 2020July 3, 2023CARRICO, ADAM WAYNEreporter.nih.gov
Human/Animal Brain Chimera in drugs of abuse and HIVNIHNational Institute on Drug Abuse2022 to 2025$2,144,306August 15, 2022May 31, 2027AL-HARTHI, LENAreporter.nih.gov
Cocaine-induced adaptation in NMDA receptorsNIHNational Institute on Drug Abuse2021 to 2025$2,139,400December 1, 2022November 30, 2027DONG, YANreporter.nih.gov
1/2 Treating Mothers with ADHD and their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation TrialNIHNational Institute of Mental Health2021 to 2023$2,137,454August 7, 2019July 31, 2024STEIN, MARK Areporter.nih.gov
Comorbidities and other consequences at the intersection of the HIV and substance use epidemicsNIHNational Institute on Drug Abuse2023 to 2025$2,110,949September 1, 2023June 30, 2028CRANE, HEIDI M.reporter.nih.gov
Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$2,107,134June 1, 2019May 31, 2025DEDERT, ERIC Areporter.nih.gov
Inflammasome activation in an SIV-ART model of chronic drug abuseNIHNational Institute on Drug Abuse2021 to 2023$2,104,458September 30, 2019July 31, 2025VEENHUIS, REBECCA TERILLIreporter.nih.gov
Individual Differences & Cocaine Effects on Impulsive Choice in RatNIHNational Institute on Drug Abuse2022 to 2025$2,102,499July 1, 2016March 31, 2027TAYLOR, JANE Rreporter.nih.gov
Stimulant-induced excitatory and inhibitory dopamine receptor signaling and traffickingNIHNational Institute on Drug Abuse2023 to 2025$2,098,117September 30, 2023June 30, 2028SANDER, CHRISTIN Y.reporter.nih.gov
Cerebral organoid and IPSC derived microglia: Modeling of HIV and methamphetamine co-morbidityNIHNational Institute on Drug Abuse2022 to 2025$2,096,889September 1, 2022July 31, 2027YELAMANCHILI, SOWMYAreporter.nih.gov
Immune mechanisms that shape the blood brain barrier in people living with HIV and cocaine use disorderNIHNational Institute on Drug Abuse2024 to 2025$2,096,862June 1, 2024March 31, 2029VEENHUIS, REBECCA TERILLIreporter.nih.gov
Decentralized clinical trial of contingency management digital therapeutic to treat stimulant use disorderNIHNational Institute on Drug Abuse2024 to 2025$2,087,604September 15, 2024August 31, 2027GASTFRIEND, DAVID Rreporter.nih.gov
Risk Factors for Psychosis and Mania with Prescription Amphetamine UseNIHNational Institute of Mental Health2021 to 2023$2,082,432June 10, 2020April 30, 2025SHINN, ANN KYUNGAHreporter.nih.gov
Benzodiazepine Choice and Polydrug UseNIHNational Institute on Drug Abuse2022 to 2025$2,074,200April 1, 2022January 31, 2027HUSKINSON, SALLY Lreporter.nih.gov
Neuroimmune pathways linking chronic psychosocial stress to co-occurring stimulant use and depression in HIV disease: a mechanistic clinical trialNIHNational Institute on Drug Abuse2024 to 2025$2,071,030September 1, 2024May 31, 2029MEADE, CHRISTINA Sreporter.nih.gov
New psychoactive substance exposure among NYC nightclub and festival attendeesNIHNational Institute on Drug Abuse2023 to 2025$2,051,804August 15, 2023May 31, 2027PALAMAR, JOSEPH Jreporter.nih.gov
Influence of Orexin Antagonism on Opioid and Methamphetamine DemandNIHNational Institute on Drug Abuse2023 to 2025$2,047,388April 15, 2023December 1, 2025STRICKLAND, JUSTIN CHARLESreporter.nih.gov
Dopaminergic and Glutamatergic Mechanisms of Cocaine Addiction: Sex DifferencesNIHNational Institute on Drug Abuse2022 to 2025$2,046,903April 1, 2008May 31, 2027LYNCH, WENDY JEANreporter.nih.gov
Targeting gut brain-signaling to reduce cocaine seeking behaviorsNIHNational Institute on Drug Abuse2023 to 2025$2,040,985September 1, 2023June 30, 2028KIRALY, DREWreporter.nih.gov
Supporting data-driven decision-making to support substance use service expansion policies and to prevent overdosesNIHNational Institute on Drug Abuse2024 to 2025$2,033,987September 1, 2023August 31, 2028CRUDEN, GRACELYNreporter.nih.gov
Retinoic acid, homeostatic plasticity and cocaine cravingNIHNational Institute on Drug Abuse2021 to 2024$2,026,004March 15, 2020December 31, 2025WOLF, MARINA ELIZABETHreporter.nih.gov
Developing a U.S. National Cohort to Improve Virologic Suppression among Stimulant-using Men Living with HIV.NIHNational Institute on Drug Abuse2023 to 2024$2,024,874May 15, 2023April 30, 2025SPINELLI, MATTHEW A.reporter.nih.gov
Glutamate receptor plasticity underlying incubation of methamphetamine cravingNIHNational Institute on Drug Abuse2021 to 2025$2,013,645September 1, 1996March 31, 2028WOLF, MARINA ELIZABETHreporter.nih.gov
Uptake2 transporters: Novel sex-dependent molecular targets to treat stimulant use disorderNIHNational Institute on Drug Abuse2023 to 2025$2,011,549July 15, 2023May 31, 2028DAWS, LYNETTE Creporter.nih.gov
Neural mechanisms regulating cocaine consumptionNIHNational Institute on Drug Abuse2021 to 2024$2,000,599July 15, 2020April 30, 2026PHILLIPS, PAUL E. M.reporter.nih.gov
Mitochondrial signaling dynamics in cocaine use disorderNIHNational Institute on Drug Abuse2023 to 2025$1,977,342August 15, 2023June 30, 2028ABRAHAM, ANTONY DANIELreporter.nih.gov
X chromosome inactivation in sex disparities to substance use disorderNIHNational Institute on Drug Abuse2021 to 2025$1,974,500August 15, 2021May 31, 2027OGHUMU, STEVE ONYEKAreporter.nih.gov
Stimulant and Polysubstance use, Inflammation and Sex Effects on Myocardial Disease in HIV (SPISE)NIHNational Institute on Drug Abuse2025$1,969,877July 15, 2025March 31, 2030TIEN, PHYLLIS Creporter.nih.gov
Integration of Peer Navigation and mHealth Technology to Improve Viral Suppression among Racial and Ethnic Minority PLWH in Community-Based HIV Care ClinicsNIHNational Institute on Drug Abuse2021 to 2023$1,963,075September 30, 2020July 31, 2025PITPITAN, EILEEN VIRTUSIOreporter.nih.gov
The Role of the Bed Nucleus of the Stria Terminalis-Norepinephrine System in Amphetamine-type Stimulant Use DisordersNIHNational Institute on Drug Abuse2023 to 2025$1,958,010September 15, 2023June 30, 2028PARK, JINWOOreporter.nih.gov
Novel Addiction Neurocircuits in Cocaine TakingNIHNational Institute on Drug Abuse2022 to 2025$1,955,360April 1, 2022January 31, 2027HOMMEL, JONATHAN DEANreporter.nih.gov
Effects of HIV-1 Tat protein and methamphetamine on VMAT2-mediated dopamine transmission in the context of neuroHIV and drug abuseNIHNational Institute on Drug Abuse2023 to 2025$1,939,156April 1, 2023April 30, 2025ZHU, JUNreporter.nih.gov
Examining predictors of substance use and treatment adequacy among formerly incarcerated opiod and cocaine usersNIHNational Institute on Drug Abuse2022 to 2024$1,937,137August 1, 2022June 30, 2027ROWELL-CUNSOLO, TAWANDRA LASHONEreporter.nih.gov
Regulation of striatal microcircuits by endogenous opioids as a novel mechanism underlying cocaine seekingNIHNational Institute on Drug Abuse2022 to 2025$1,936,984August 1, 2022May 31, 2027DOBBS, LAUREN Kreporter.nih.gov
Relationship between methamphetamine use, viral reservoir dynamics and clinical progression in treated HIV infectionNIHNational Institute on Drug Abuse2023 to 2025$1,936,729June 1, 2023April 30, 2028STEVENSON, MARIOreporter.nih.gov
Cocaine: effects on single neuronsNIHNational Institute on Drug Abuse2021 to 2025$1,925,000July 1, 1987July 31, 2027WILLIAMS, JOHN Treporter.nih.gov
SARS-CoV-2 signaling and interactions with stimulant drugs of abuse via Sigma-1R: Impact on the BBBNIHNational Institute on Drug Abuse2022 to 2025$1,914,927July 1, 2022April 30, 2027UNTERWALD, ELLEN Mreporter.nih.gov
Methamphetamine, mitochondria, and neurodegenerationNIHNational Institute on Drug Abuse2021 to 2025$1,908,298April 15, 2021January 31, 2027GRAVES, STEVEN MICHAELreporter.nih.gov
Determinants of Drug Preference in HumansNIHNational Institute on Drug Abuse2021 to 2024$1,905,360January 1, 1981January 31, 2026DE WIT, HARRIETreporter.nih.gov
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasomeNIHNational Institute on Drug Abuse2021 to 2023$1,904,596September 30, 2019July 31, 2025BUCH, SHILPA J.reporter.nih.gov
Methamphetamine Effects on Prefrontal Cortical PV+ Interneurons and Resulting Cognitive DeficitsNIHNational Institute on Drug Abuse2021 to 2025$1,891,855September 1, 2021July 31, 2026LAVIN, ANTONIETAreporter.nih.gov
Development and validation of a novel point-of-care technology for rapid non-targeted identification of emerging opioid and other drug threatsNIHNational Institute on Drug Abuse2023 to 2025$1,866,922September 30, 2023August 31, 2027WERB, DANIEL Mreporter.nih.gov
Pioglitazone as an adjunct to CBT for cocaine relapse preventionNIHNational Institute on Drug Abuse2021 to 2023$1,864,756July 1, 2020May 31, 2025SCHMITZ, JOY MARIEreporter.nih.gov
Optimizing PrEP adherence in sexual minority men who use stimulantsNIHNational Institute on Drug Abuse2023 to 2024$1,855,864July 1, 2020May 31, 2025CARRICO, ADAM WAYNEreporter.nih.gov
Glutamergic Mechanisms in Opioid and Cocaine Co-UseNIHNational Institute on Drug Abuse2022 to 2024$1,854,763September 30, 2020August 31, 2025GIPSON-REICHARDT, CASSANDRA Dreporter.nih.gov
Screen, Treat and Retain People with Primary Meth Use Disorder at MMT Clinics (STAR-OM+)NIHNational Institute on Drug Abuse2021 to 2024$1,829,872May 1, 2024March 31, 2025LE, GIANG Mreporter.nih.gov
Developing a U.S. National Cohort to Improve Virologic Suppression among Stimulant-using Men Living with HIV.NIHNational Institute on Drug Abuse2025$1,828,735May 15, 2023April 30, 2028SPINELLI, MATTHEW A.reporter.nih.gov
The role of RGS12 in differential modulation of G protein versus beta-arrestin signaling downstream of the kappa opioid receptorNIHNational Institute on Drug Abuse2021 to 2025$1,819,514February 15, 2021December 31, 2025SIDEROVSKI, DAVID P.reporter.nih.gov
Structure and Function of Neurotransmitter TransportersNIHNational Institute of Mental Health2025$1,810,118July 1, 2004May 31, 2029GOUAUX, JAMES Ereporter.nih.gov
Incubated drug-craving and neurochemical interactionsNIHNational Institute on Drug Abuse2021 to 2025$1,780,211April 15, 2021December 31, 2025SZUMLINSKI, KAREN KATHLEENreporter.nih.gov
Mining Social Media Big Data for Toxicovigilance: Studying Substance Use via Natural Language Processing and Machine Learning MethodsNIHNational Institute on Drug Abuse2022 to 2025$1,773,166September 30, 2022July 31, 2027SARKER, ABEED Hreporter.nih.gov
Neural systems mediating the extinction and inhibition of cocaine seekingNIHNational Institute on Drug Abuse2021 to 2024$1,771,684July 15, 2020April 30, 2026LALUMIERE, RYAN Treporter.nih.gov
Mechanisms underlying the influence of stress on drug-seeking behaviorNIHNational Institute on Drug Abuse2023 to 2025$1,764,926July 1, 2023April 30, 2028MANTSCH, JOHN Rreporter.nih.gov
Systems biology of RNA Modifications in HIV/AIDS and Substance Use DisordersNIHNational Institute on Drug Abuse2021 to 2022$1,760,840March 15, 2018December 31, 2023SANNA, PIETRO Preporter.nih.gov
Rapid and non-invasive device for drug detection through sweatNIHNational Institute on Drug Abuse2022 to 2023$1,738,402September 30, 2020July 31, 2025KULKARNI, GIRISHreporter.nih.gov
Calcium-related neurotoxicity of cocaineNIHNational Institute on Drug Abuse2021 to 2025$1,729,326February 15, 2012January 31, 2027DU, CONGWUreporter.nih.gov
Molecular mechanisms: Dysregulation of monoamine transporters by HIV-1 Tat and cocaineNIHNational Institute on Drug Abuse2021 to 2024$1,726,798July 1, 2013April 30, 2025ZHU, JUNreporter.nih.gov
Hippocampal mechanisms of cocaine-memory reconsolidationNIHNational Institute on Drug Abuse2023 to 2025$1,719,615June 1, 2023March 30, 2028FUCHS LOKENSGARD, RITA Areporter.nih.gov
Methamphetamine injection, associated health risk, and causes of overdose deaths.NIHNational Institute on Drug Abuse2022 to 2024$1,714,422September 30, 2022July 31, 2025KRAL, ALEXANDER Hreporter.nih.gov
PACAP-Dependent Coordination of Glutamate Signaling between Neurons and AstrocytesNIHNational Institute on Drug Abuse2021 to 2025$1,708,450August 15, 2020April 30, 2027BAKER, DAVID Areporter.nih.gov
Short-term and long-term effects of methamphetamine exposure on residual viral transcription during treated HIV diseaseNIHNational Institute on Drug Abuse2024 to 2025$1,702,671August 1, 2018May 31, 2026LEE, SULGGI ANGELAreporter.nih.gov
Nitrergic interneurons and cue-induced cocaine seekingNIHNational Institute on Drug Abuse2021 to 2025$1,697,532August 1, 2021May 31, 2027SCOFIELD, MICHAEL DAVIDreporter.nih.gov
Genetic and hormonal contributions to sex differences in vulnerability to drug useNIHNational Institute on Drug Abuse2021 to 2024$1,691,545March 1, 2020December 31, 2025LYNCH, WENDY JEANreporter.nih.gov
Nature and Predictors of Impaired Harm Avoidance in Polysubstance AbuseNIHNational Institute on Drug Abuse2021 to 2023$1,690,491July 1, 2018June 30, 2026OTTO, MICHAEL W.reporter.nih.gov
Translational Research Training in Addictions: Pathways for Behavioral and Biomedical Scholars (TRACC).NIHNational Institute on Drug Abuse2021 to 2025$1,690,151June 15, 2013June 30, 2030RUGLASS, LESIA MONIQUEreporter.nih.gov
Regulation of Dopamine Transporter by TraffickingNIHNational Institute on Drug Abuse2021 to 2025$1,683,175April 1, 2001June 30, 2028SORKIN, ALEXANDER Dreporter.nih.gov
The impact of methamphetamine on CXCL12 mediated HIV neuropathogenesisNIHNational Institute on Drug Abuse2022 to 2025$1,680,000July 15, 2022May 31, 2027BERMAN, JOAN WEINBERGERreporter.nih.gov
Diurnal rhythms in the nucleus accumbens: Mechanisms and role in substance use disordersNIHNational Institute on Drug Abuse2021 to 2024$1,678,144July 1, 2015March 31, 2026MCCLUNG, COLLEEN Areporter.nih.gov
Host and viral genomic determinants of HIV latent reservoir size and characteristics in individuals with substance use disordersNIHNational Institute on Drug Abuse2022 to 2023$1,677,906August 15, 2018May 31, 2024SILICIANO, ROBERT Freporter.nih.gov
Cognitive Reappraisal for Mitigating Incubation of Cocaine Cue-ReactivityNIHNational Institute on Drug Abuse2024 to 2025$1,675,624September 30, 2023August 31, 2028PARVAZ, MUHAMMAD ADEELreporter.nih.gov
Assessing central muscarinic acetylcholine type-1 receptors in cocaine use disorder with 11C-LSN3172176.NIHNational Institute on Drug Abuse2024 to 2025$1,664,691April 15, 2022June 30, 2027ANGARITA, GUSTAVO ADOLFOreporter.nih.gov
Synaptic Actions of Amphetamine in the StriatumNIHNational Institute on Drug Abuse2023 to 2025$1,661,845April 1, 2023January 31, 2028RAYPORT, STEPHENreporter.nih.gov
Non-beta-lactam GLT-1 activators: characterization in preclinical models of opioid and cocaine addictionNIHNational Institute on Drug Abuse2021 to 2024$1,661,677September 30, 2020June 30, 2025RAWLS, SCOTT M.reporter.nih.gov
Circuitry and function of ventral striatum subregionsNIHNational Institute on Drug Abuse2021 to 2024$1,660,649April 1, 2020January 31, 2026WESSON, DANIEL Wreporter.nih.gov
Role of lateral habenula in methamphetamine TAAR1-mediated synaptic plasticity and aversionNIHNational Institute on Drug Abuse2023 to 2025$1,656,889September 30, 2023June 30, 2028INGRAM, SUSAN Lreporter.nih.gov
Memory Destabilization and Cocaine-Cue Induced Reinstatement in RatNIHNational Institute on Drug Abuse2021 to 2025$1,653,750July 1, 2021April 30, 2027TAYLOR, JANE Rreporter.nih.gov
L-Type Calcium Channel Mechanisms Mediating Comorbid Substance Use and Mood DisordersNIHNational Institute on Drug Abuse2021 to 2024$1,645,542September 30, 2020July 31, 2025ADDY, NII Areporter.nih.gov
Structure and Function of Neurotransmitter TransportersNIHNational Institute of Mental Health2021 to 2024$1,623,458July 1, 2004May 31, 2029GOUAUX, JAMES Ereporter.nih.gov
Development of selective cannabinoid receptor 2 agonists for treatment of addictionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,621,997April 19, 2022April 30, 2027SHAMLOO, MEHRDADreporter.nih.gov
Epigenetic regulation of Cdk5 in cognition and emotionNIHNational Institute of Mental Health2023 to 2025$1,621,522January 1, 2023October 31, 2027HELLER, ELIZABETH Areporter.nih.gov
The Role of Microbiome Composition in Amphetamine AbuseNIHNational Institute on Drug Abuse2023 to 2025$1,621,263August 15, 2023May 31, 2028GALLI, AURELIOreporter.nih.gov
Transdermal Rotigotine as Adjunct to Behavioral Therapy for Cocaine Use DisorderNIHNational Institute on Drug Abuse2022$1,597,923September 30, 2022September 29, 2025BJORK, JAMES Mreporter.nih.gov
Vagus nerve stimulation increases basal dopamine levels in the brain to decrease methamphetamine-mediated responsesNIHNational Institute on Drug Abuse2023 to 2025$1,595,645August 1, 2023May 31, 2028KHOSHBOUEI, HABIBEHreporter.nih.gov
Transgenerational Inheritance of a Cocaine Resistance PhenotypeNIHNational Institute on Drug Abuse2023 to 2025$1,594,735April 1, 2012January 31, 2027PIERCE, ROBERT CHRISTOPHERreporter.nih.gov
Cholinergic interneuron D2 receptor function in impulsive behavior: implications for addictionNIHNational Institute on Drug Abuse2022 to 2025$1,571,833July 1, 2022May 31, 2027GALLO, EDUARDO FRANCISCOreporter.nih.gov
Supporting Treatment Adherence for Resilience and Thriving (START): A mHealth intervention to improve ART adherence for HIV-positive stimulant-using menNIHNational Institute on Drug Abuse2021 to 2022$1,555,079September 30, 2019July 31, 2024CARRICO, ADAM WAYNEreporter.nih.gov
Vagus nerve stimulation modulates synaptic plasticity in the rat prefrontal cortex during the extinction of drug-seekingNIHNational Institute on Drug Abuse2022 to 2025$1,554,112April 1, 2022January 31, 2027KROENER, SVENreporter.nih.gov
Engaging People Who Use Drugs in Harm Reduction Service Delivery: An Intravention to Reduce Risk of HIV, HCV, Overdose, and Injection-related Infections in Rural AppalachiaNIHNational Institute on Drug Abuse2024$1,533,697September 30, 2024August 31, 2026YOUNG, APRIL MARIEreporter.nih.gov
Genetic Control of Addiction by Host and MicrobiomeNIHNational Institute on Drug Abuse2021 to 2022$1,533,193September 30, 2018July 31, 2024BUBIER, JASON Areporter.nih.gov
Neural circuitry and functional significance of extra-SCN pacemakersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,529,842September 15, 2020June 30, 2026YAMAZAKI, SHINreporter.nih.gov
Domain- and protein-selective BET mechanisms in cocaine-seeking behaviorsNIHNational Institute on Drug Abuse2023 to 2025$1,521,368August 1, 2023May 31, 2028SARTOR, GREGORY CHARLESreporter.nih.gov
Effects of intrinsic and drug-induced neuromodulation on functional brain imagingNIHNational Institute on Drug Abuse2021 to 2024$1,517,943August 1, 2020May 31, 2025DEVOR, ANNAreporter.nih.gov
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and CocaineNIHNational Institute on Drug Abuse2021 to 2023$1,515,246August 15, 2021June 30, 2024GUO, MINGLEIreporter.nih.gov
Pharmacologic augmentation of targeted cognitive training in schizophreniaNIHNational Institute of Mental Health2021 to 2022$1,511,158August 6, 2020July 31, 2024SWERDLOW, NEAL Rreporter.nih.gov
The neuropharmacology of brain activation during stages of drug abuseNIHNational Institute on Drug Abuse2023 to 2025$1,503,000April 1, 2023February 29, 2028SANDER, CHRISTIN Y.reporter.nih.gov
Social support, oxytocin and motivation for methamphetamineNIHNational Institute on Drug Abuse2021 to 2023$1,502,424July 15, 2019April 30, 2025BECKER, JILL B.reporter.nih.gov
Gene Regulation in Memory Circuits as a Consequence of Polysubstance UseNIHNational Institute on Drug Abuse2023 to 2025$1,500,894August 1, 2023June 30, 2028KAUN, KARLA R.reporter.nih.gov
Phase 0/1b Clinical Trial of Novel Therapeutic Agent MT-110 for the Reduction of Methamphetamine Use - Part 2NIHNational Institute on Drug Abuse2025$1,496,586April 1, 2025February 28, 2028YOUNG, ERICA Jreporter.nih.gov
Modular, in-situ probes of brain chemistryNIHNational Institute on Drug Abuse2021 to 2023$1,496,151August 1, 2020April 30, 2025PLAXCO, KEVIN Wreporter.nih.gov
Restoration and Further Assessment of the Actor-Critic Circuit and Connected Areas After Cocaine Self-AdministrationNIHNational Institute on Drug Abuse2021 to 2025$1,495,707July 1, 2011February 29, 2028ROESCH, MATTHEW Rreporter.nih.gov
Short Sleep Duration as a Predictor of Methamphetamine Intake: Role of Orexin MechanismsNIHNational Institute on Drug Abuse2024 to 2025$1,492,883July 15, 2024April 30, 2029BERRO, LAIS Freporter.nih.gov
Deep TMS Neuromodulation of Neural Circuits Associated with Stimulant Use DisorderNIHNational Institute on Drug Abuse2024$1,491,755September 15, 2024August 31, 2026PADULA, CLAUDIA B.reporter.nih.gov
A novel opioid receptor antagonist for treating abuse and overdoseNIHNational Institute on Drug Abuse2021 to 2023$1,477,314April 1, 2019February 28, 2025FRANCE, CHARLES Preporter.nih.gov
Assessing the role of corticostriatal circuitry in polysubstance use of fentanyl and methamphetamine using rat self-administration modelsNIHNational Institute on Drug Abuse2023 to 2025$1,475,011June 15, 2023April 30, 2028FERGUSON, SUSAN MARIEreporter.nih.gov
Glutamate and Craving for CocaineNIHNational Institute on Drug Abuse2021 to 2024$1,472,920February 10, 2000March 31, 2025KALIVAS, PETER Wreporter.nih.gov
Examining Mechanisms Underlying Drug-Associated Memory Erasure by Zeta-Inhibitory PeptideNIHNational Institute on Drug Abuse2021 to 2023$1,470,367April 15, 2019January 31, 2025BRIAND, LISA Areporter.nih.gov
Methamphetamine Activation of Inflammasome and Altered immunity in HIV (MAIA) StudyNIHNational Institute on Drug Abuse2024 to 2025$1,456,335September 30, 2024July 31, 2029PEREIRA RIBEIRO, SUSANreporter.nih.gov
New Technologies for Accelerating the Discovery and Characterization of Neuroactives that Address Substance Use DisordersNIHNational Institute on Drug Abuse2023 to 2025$1,453,500April 1, 2023February 29, 2028MCCARROLL, MATTHEW Nreporter.nih.gov
Systems genetics of premorbid and cocaine use traits in a rat reduced complexity crossNIHNational Institute on Drug Abuse2022 to 2023$1,444,164May 1, 2022December 31, 2023KANTAK, KATHLEEN M.reporter.nih.gov
Bath Salts: abuse-related and toxic effectsNIHNational Institute on Drug Abuse2021 to 2024$1,439,490April 1, 2015March 31, 2026COLLINS, GREGORY THOMASreporter.nih.gov
Identification of Biomarkers of CNS injury and resilience related to HIV-1 and MethamphetamineNIHNational Institute on Drug Abuse2021 to 2022$1,427,395September 15, 2018June 30, 2025IUDICELLO, JENNIFER Ereporter.nih.gov
Experience-Dependent Regulation of Reward Learning and Addiction VulnerabilityNIHNational Institute on Drug Abuse2022 to 2025$1,426,500March 1, 2022December 31, 2026MORIKAWA, HITOSHIreporter.nih.gov
Dissecting the role of ventral pallidal circuitry in cocaine seeking after the withdrawalNIHNational Institute on Drug Abuse2021 to 2024$1,425,586July 15, 2020April 30, 2025LIM, BYUNGKOOKreporter.nih.gov
Neurotensin receptor 1 as a novel target for opioid use disorder and discovery of new small molecule probesNIHNational Institute on Drug Abuse2024 to 2025$1,418,702September 15, 2024May 31, 2029SLOSKY, LAUREN Mreporter.nih.gov
The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latencyNIHNational Institute on Drug Abuse2024 to 2025$1,417,276May 15, 2024February 28, 2029KARN, JONATHANreporter.nih.gov
Targeting autophagy to reduce inflammasome-mediated inflammation and immune dysfunction in HIV and methamphetamine useNIHNational Institute on Drug Abuse2024 to 2025$1,416,081June 1, 2024March 31, 2029ZHEN, ANJIEreporter.nih.gov
Evaluation of Drug Checking as a Novel Intervention to Address the Opioid Overdose Crisis Attributable to Fentanyl and its AnaloguesNIHNational Institute on Drug Abuse2021 to 2023$1,404,636September 30, 2021January 31, 2026TI, LIANPINGreporter.nih.gov
Neural Mechanisms of Individual Differences in Cocaine AvoidanceNIHNational Institute on Drug Abuse2023 to 2025$1,404,531August 1, 2021May 31, 2026JHOU, THOMAS Creporter.nih.gov
Impacts of drug abuse-mediated inflammatory perturbations on affinity maturation of anti-CD4 autoantibodies and poor immune reconstitution from ART in HIVNIHNational Institute on Drug Abuse2024 to 2025$1,402,812September 30, 2024May 31, 2029JIANG, WEIreporter.nih.gov
Modulating ventral striatal activity and connectivity with transcranial focused ultrasound as a putative novel intervention for cocaine use disorderNIHNational Institute on Drug Abuse2024 to 2025$1,395,182June 15, 2024May 31, 2027PHILLIPS, MARY LOUISEreporter.nih.gov
Selective Targeting of Nicotinic Acetylcholine Receptor Subtypes for Cocaine Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$1,393,000March 1, 2024December 31, 2028RILEY, ANDREWreporter.nih.gov
Multidisciplinary Characterization of the Gut-Brain Axis in AddictionNIHNational Center for Complementary & Integrative Health2024$1,391,376September 17, 2024August 31, 2027CUESTA, SANTIAGOreporter.nih.gov
Estrogen regulation of the prefrontal cortex and drug seekingNIHNational Institute on Drug Abuse2021 to 2024$1,390,995July 1, 2020April 30, 2026MANTSCH, JOHN R.reporter.nih.gov
Multimodal brain imaging of the neural effects of methylphenidate in patients with ADHDNIHNational Institute of Mental Health2024 to 2025$1,382,029December 1, 2023November 30, 2028BIGOS, KRISTIN Lreporter.nih.gov
Using Omics to Understand the Effects of Drug Abuse on HIV Latent ReservoirNIHNational Institute on Drug Abuse2021 to 2022$1,377,622August 15, 2018May 31, 2025JOHNSON, ERIC OTTOreporter.nih.gov
Cell type transcriptional mechanisms of polysubstance choiceNIHNational Institute on Drug Abuse2023 to 2025$1,376,550July 1, 2023May 31, 2028HAMILTON, PETER JAMESreporter.nih.gov
Sleep Disturbances During Cocaine Abstinence, Dopamine Adaptations, and Motivation for CocaineNIHNational Institute on Drug Abuse2023 to 2025$1,375,686May 1, 2023February 29, 2028ESPAÑA, RODRIGO A.reporter.nih.gov
Animal Models of AddictionNIHNational Institute on Drug Abuse2021 to 2023$1,368,000December 1, 2018November 30, 2024FERRARIO, CARRIEreporter.nih.gov
Deep Brain Stimulation (DBS) For Severe Treatment Refractory Methamphetamine Use DisorderNIHNational Institute on Drug Abuse2022 to 2023$1,366,011June 1, 2022May 31, 2025SAKAI, JOSEPH Treporter.nih.gov
Pathway-specific Intervention in Prelimbic Cortical Circuitry Decreases Cocaine-seekingNIHNational Institute on Drug Abuse2021 to 2024$1,357,969September 30, 2020July 31, 2025MCGINTY, JACQUELINE F.reporter.nih.gov
Regulating dopamine transport through allosteric modulation - Functional and Behavioral StudiesNIHNational Institute on Drug Abuse2024 to 2025$1,337,160September 15, 2024May 31, 2029MORTENSEN, OLE VALENTEreporter.nih.gov
A novel robotic wastewater analysis system to quantify opioid exposure and treatment in residential communitiesNIHNational Institute on Drug Abuse2021 to 2022$1,336,341February 1, 2022December 31, 2023MATUS GARCIA, MARIANA Greporter.nih.gov
17α-estradiol and sex-differences in HAND with methamphetamineNIHNational Institute on Drug Abuse2023 to 2025$1,333,494September 1, 2023July 31, 2028CHEN, XUESONGreporter.nih.gov
Dissecting the shared genetic mechanisms driving fentanyl addiction, cocaine addiction, and incentive sensitization using the Collaborative Cross mouse panelNIHNational Institute on Drug Abuse2024 to 2025$1,331,986June 1, 2024March 31, 2029DICKSON, PRICE EVANSreporter.nih.gov
CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSENIHNational Institute on Drug Abuse2023 to 2024$1,327,322June 1, 2019March 31, 2026AKBARIAN, SCHAHRAMreporter.nih.gov
Systems genetics of premorbid and cocaine use traits in a rat reduced complexity crossNIHNational Institute on Drug Abuse2024 to 2025$1,325,341March 7, 2024February 28, 2028BRYANT, CAMRON Dreporter.nih.gov
Involvement of Cortical Excitatory Projections in Cocaine AddictionNIHNational Institute on Drug Abuse2024 to 2025$1,324,728September 30, 2024May 31, 2029MA, YAO-YINGreporter.nih.gov
Microglial modulation of neurocircuits in HIV/cocaine comorbidityNIHNational Institute on Drug Abuse2023 to 2024$1,323,376June 1, 2023March 31, 2025BOOZE, ROSEMARIE Mreporter.nih.gov
A cutaneous gene therapy for cocaine abuse and alcohol co-abuseNIHNational Institute on Drug Abuse2021 to 2023$1,312,200September 30, 2019July 31, 2025XU, MINGreporter.nih.gov
Ventral pallidum molecular mediators in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2023$1,302,852February 1, 2019November 30, 2024LOBO, MARY KAYreporter.nih.gov
Dopamine system as reporter of HIV status and inflammation in Meth abusersNIHNational Institute on Drug Abuse2021 to 2023$1,302,264February 1, 2019January 31, 2025MARCONDES, MARIA CECILIA GARIBALDIreporter.nih.gov
Exercise in Methamphetamine Use Disorder: Dopamine Receptor Upregulation and Neural FunctionNIHNational Institute on Drug Abuse2021 to 2022$1,297,577July 1, 2018April 30, 2024LONDON, EDYTHE DANICKreporter.nih.gov
Opioid and Psychostimulant Taking: Testing the Impact of Behavioral Economic ContextsNIHNational Institute on Drug Abuse2022 to 2025$1,280,955September 15, 2022July 31, 2027KEARNS, DAVID Nreporter.nih.gov
Development of the Stimulant Use Disorder Severity ScaleNIHNational Institute on Drug Abuse2021 to 2023$1,280,880July 1, 2020March 31, 2023KILUK, BRIAN D.reporter.nih.gov
Influence of 5-HT1b Activation on the Abuse Related Effects of CocaineNIHNational Institute on Drug Abuse2021 to 2022$1,280,534August 1, 2021July 31, 2025STOOPS, WILLIAM WALTONreporter.nih.gov
HIV and cocaine use leads to loss of astrocyte neurotrophic support and impaired lipid homeostasis in the brainNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,272,487September 20, 2022August 31, 2026LANGFORD, DIANNE TERESAreporter.nih.gov
The dopamine transporter's lipid interactions: understanding transporter functionNIHNational Institute on Drug Abuse2021 to 2023$1,267,956April 1, 2014December 31, 2025GALLI, AURELIOreporter.nih.gov
Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families Involved in Systems with Parental Opioid and Methamphetamine UseNIHNational Institute on Drug Abuse2025$1,261,490September 15, 2025May 31, 2030SALDANA, LISAreporter.nih.gov
Dopamine modulation for the treatment of chronic dysfunction due to traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,257,620May 15, 2019April 30, 2025VONDER HAAR, COLEreporter.nih.gov
Functional Dynamics of Neurotransmitter:Sodium Symporters (NSSs)NIHNational Institute of Mental Health2024 to 2025$1,243,576September 12, 2024June 30, 2029QUICK, MATTHIASreporter.nih.gov
Antecedents and Consequences of Cocaine Taking: Impact of OxytocinNIHNational Institute on Drug Abuse2021 to 2022$1,241,165September 1, 2017May 31, 2024EVANS, SUZETTE Mreporter.nih.gov
K channel, NLRP3 inflammasome and Meth exacerbation of HANDNIHNational Institute on Drug Abuse2021 to 2023$1,234,632September 30, 2019June 30, 2025XIONG, HUANGUI HANKreporter.nih.gov
Identification and Regulation of RNA Modification by HIV infection and MethamphetamineNIHNational Institute on Drug Abuse2021 to 2022$1,232,056April 1, 2018January 31, 2025RANA, TARIQ Mreporter.nih.gov
Human dopamine transporter gene: variation and transcriptional regulationNIHNational Institute on Drug Abuse2021 to 2024$1,230,000September 1, 2007July 31, 2025LIN, ZHICHENG CARLreporter.nih.gov
Genomic Analysis of Avoidance Learning in AddictionNIHNational Institute on Drug Abuse2021 to 2022$1,223,491April 15, 2018June 4, 2023JHOU, THOMAS Creporter.nih.gov
A translational determination of the mechanisms of maladaptive choice in cocaine use disorderNIHNational Institute on Drug Abuse2021 to 2022$1,222,073July 1, 2018April 30, 2024LILE, JOSHUA ANTHONYreporter.nih.gov
Estradiol signaling pathways mediating sex differences in striatal synaptic plasticityNIHNational Institute on Drug Abuse2024 to 2025$1,218,955February 1, 2024January 31, 2028BLACKWELL, KIM Lreporter.nih.gov
Psychostimulant-Induced Plasticity of Nucleus Accumbens InterneuronsNIHNational Institute on Drug Abuse2021 to 2023$1,216,840April 1, 2019July 31, 2024WEST, ANNE ELIZABETHreporter.nih.gov
Diagnostic and prognostic biomarkers for subtypes of addiction-related circuit dysfunctionNIHNational Institute on Drug Abuse2021 to 2022$1,207,946August 1, 2019May 31, 2024LISTON, CONOR Mreporter.nih.gov
Low-intensity focused ultrasound for cocaine use disorder: High resolution targeting of the human insulaNIHNational Institute on Drug Abuse2022 to 2023$1,197,126August 1, 2022January 31, 2025AIT-DAOUD, NASSIMAreporter.nih.gov
Trajectories of Prescription Nonmedical Drug MisuseNIHNational Institute on Drug Abuse2021 to 2025$1,194,681April 1, 2011March 31, 2028MCCABE, SEAN ESTEBANreporter.nih.gov
The role of central GLP-1 receptors in animal models of cocaine addictionNIHNational Institute on Drug Abuse2021 to 2023$1,188,835March 1, 2015May 31, 2025SCHMIDT, HEATH Dreporter.nih.gov
Dissecting the Abuse Liability of Cathinone and Amphetamine StimulantsNIHNational Institute on Drug Abuse2023 to 2025$1,185,000September 30, 2016July 31, 2028TAFFE, MICHAEL A.reporter.nih.gov
Dissection of Addiction Relevant Signal Integration by Cyfip2 through Precise Genome EngineeringNIHNational Institute on Drug Abuse2021 to 2024$1,178,521July 15, 2020June 30, 2025KUMAR, VIVEKreporter.nih.gov
Methamphetamine, HIV integration and latency in the brainNIHNational Institute on Drug Abuse2023 to 2024$1,175,173September 30, 2023August 31, 2025MARCONDES, MARIA CECILIA GARIBALDIreporter.nih.gov
A2: Striosomal models of drug use and costNIHNational Institute on Drug Abuse2024 to 2025$1,173,870September 15, 2024May 31, 2029FRIEDMAN, ALEXANDERreporter.nih.gov
Mechanistic studies of alcohol-sleep interactionsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,173,750September 17, 2019August 31, 2025TORREGROSSA, MARY Mreporter.nih.gov
Incubation of oxycodone craving and nucleus accumbens plasticityNIHNational Institute on Drug Abuse2024 to 2025$1,166,080September 30, 2024May 31, 2029WOLF, MARINA ELIZABETHreporter.nih.gov
Neuronal exosomes in cocaine abuse and treatment response in socially housed monkeysNIHNational Institute on Drug Abuse2021 to 2023$1,162,500July 1, 2019April 30, 2025DEEP, GAGANreporter.nih.gov
Molecular determinants of ensemble recruitment by drugs of abuseNIHNational Institute on Drug Abuse2025$1,159,396July 1, 2025March 31, 2030CALIPARI, ERINreporter.nih.gov
Novel 5-HT2A/mGluR5 Antagonist for Opioid Use DisorderNIHNational Institute on Drug Abuse2025$1,153,945September 15, 2025August 31, 2027MOELLER, FREDERICK GERARDreporter.nih.gov
The role of norepinephrine transporter phosphorylation in amphetamine rewardNIHNational Institute on Drug Abuse2024 to 2025$1,152,433September 15, 2024July 31, 2029JAYANTHI, LANKUPALLE Dreporter.nih.gov
Inflammasome Activation and Gut-Brain Axis Dysregulation in HIV and Methamphetamine-Associated DepressionNIHNational Institute on Drug Abuse2024 to 2025$1,146,614March 15, 2024January 31, 2029TOBOREK, MICHALreporter.nih.gov
Targeted CRISPR/Cas Editing to Eliminate SIV CNS Reservoir in Methamphetamine-Exposed Rhesus Macaques on ARTNIHNational Institute on Drug Abuse2025$1,144,344August 15, 2025May 31, 2030LING, BINHUA "JULIE"reporter.nih.gov
Defining molecular mechanisms by which stimulant evoked dopamine drives inflammation and neuronal dysfunction in neuroHIVNIHNational Institute on Drug Abuse2023 to 2024$1,142,172July 1, 2023June 30, 2025GASKILL, PETER JESSEreporter.nih.gov
Identifying patterns of human polysubstance use to guidedevelopment of rodent modelsNIHNational Institute on Drug Abuse2021 to 2022$1,138,416September 30, 2018June 30, 2024KNACKSTEDT, LORI Areporter.nih.gov
Extracellular vesicles, meth relapse and sex differencesNIHNational Institute on Drug Abuse2021 to 2022$1,120,035September 30, 2018June 30, 2024PENDYALA, GURUDUTTreporter.nih.gov
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHDNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,108,211August 16, 2018July 31, 2025MARKOWITZ, JOHN Sreporter.nih.gov
Establishing a link between habits and punishment resistanceNIHNational Institute on Drug Abuse2021 to 2023$1,106,838February 15, 2019December 31, 2025SMITH, RACHEL Jreporter.nih.gov
Role of astrocytes in dopamine signaling and psychostimulant effectsNIHNational Institute on Drug Abuse2021 to 2023$1,097,250August 1, 2019May 31, 2025ARAQUE, ALFONSOreporter.nih.gov
Zona Incerta Contributions to Reward and Cocaine AddictionNIHNational Institute on Drug Abuse2021 to 2023$1,097,250September 15, 2019June 30, 2025LIU, QING-SONGreporter.nih.gov
Functional consequences of cocaine self-administration on astrocytesNIHNational Institute on Drug Abuse2023 to 2025$1,086,725May 1, 2023February 29, 2028REISSNER, KATHRYN JOANNAreporter.nih.gov
In-utero exposure to psychotropic medications and the risk of neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2022$1,078,742June 15, 2018December 31, 2023HUYBRECHTS, KRISTA Freporter.nih.gov
Multimodal profiling of microglia during HIV infection and substance use disorderNIHNational Institute on Drug Abuse2023 to 2024$1,076,164September 30, 2023August 31, 2025JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Developing a sleep EEG-based biomarker for drug relapse propensityNIHNational Institute on Drug Abuse2024 to 2025$1,075,270April 15, 2024January 31, 2029HUANG, YANHUA Hreporter.nih.gov
ROLE OF OREXIN IN COCAINE DEMAND AND ADDICTIONNIHNational Institute on Drug Abuse2023 to 2024$1,067,550August 1, 1992November 30, 2025ASTON-JONES, GARY S.reporter.nih.gov
Long-acting aldicarb hydrolase as a medical countermeasure for aldicarb poisoningNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,065,924September 1, 2023August 31, 2025ZHENG, FANGreporter.nih.gov
Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memoriesNIHNational Institute on Drug Abuse2022 to 2023$1,063,494April 1, 2022October 31, 2023RAJADHYAKSHA, ANJALI Mreporter.nih.gov
Mechanistic studies of cAMP effectors in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2023$1,062,600April 15, 2014May 31, 2025LIU, QING-SONGreporter.nih.gov
COMT inhibition as a potential therapeutic target among individuals with comorbid Alcohol Use Disorder and Attention-Deficit/Hyperactivity DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,057,280April 20, 2019March 31, 2025SCHACHT, JOSEPH P.reporter.nih.gov
Sleep regulates drug relapse and addictionNIHNational Institute on Drug Abuse2021 to 2023$1,056,375April 1, 2019January 31, 2025HUANG, YANHUA Hreporter.nih.gov
Dopamine Transporter Cell Surface DynamicsNIHNational Institute on Drug Abuse2021 to 2022$1,051,580May 1, 2013March 31, 2024MELIKIAN, HALEY Ereporter.nih.gov
Encoding dopamine signals in the mesolimbic systemNIHNational Institute on Drug Abuse2021 to 2023$1,049,625August 1, 2013February 28, 2025FORD, CHRISTOPHER PETERreporter.nih.gov
ROLE OF OREXIN IN COCAINE DEMAND AND ADDICTIONNIHNational Institute on Drug Abuse2021 to 2022$1,048,129August 1, 1992November 30, 2022ASTON-JONES, GARY S.reporter.nih.gov
Pharmacology of Stimulant ChoiceNIHNational Institute on Drug Abuse2023 to 2025$1,047,939April 15, 2023February 29, 2028BANKS, MATTHEW Lreporter.nih.gov
Extensive drug histories result in compulsive appetite: functional identification of punishment-reactive neural network re-organization in the rostromedial tegmental nucleusNIHNational Institute on Drug Abuse2022 to 2023$1,042,506September 1, 2022April 26, 2024SUTO, NOBUYOSHIreporter.nih.gov
Reprogramming KZFP function to understand drug-specific transcription and behaviorNIHNational Institute on Drug Abuse2024 to 2025$1,040,268May 1, 2024February 28, 2029HAMILTON, PETER JAMESreporter.nih.gov
Amphetamine in adolescence disrupts frontal cortex developmentNIHNational Institute on Drug Abuse2021 to 2024$1,035,897April 1, 2015July 31, 2025FLORES, CECILIAreporter.nih.gov
Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memoriesNIHNational Institute on Drug Abuse2024 to 2025$1,031,426July 1, 2020January 31, 2027RAJADHYAKSHA, ANJALI Mreporter.nih.gov
Neural Mechanisms of Individual Differences in Cocaine AvoidanceNIHNational Institute on Drug Abuse2021 to 2022$1,031,082August 1, 2021May 31, 2023JHOU, THOMAS Creporter.nih.gov
Characterization of cortical neuronal subtypes in cocaine self-administrationNIHNational Institute on Drug Abuse2021 to 2022$1,029,911August 15, 2019May 31, 2023FERGUSON, SUSAN MARIEreporter.nih.gov
An integrated incentive-based treatment to optimize HIV treatment engagement among persons who use methamphetamineNIHNational Institute on Drug Abuse2021 to 2025$1,028,700May 1, 2021April 30, 2027MONTOYA, JESSICA LYNETTEreporter.nih.gov
Epigenetic regulation of astrocyte-specific NLRP6 inflammasome and PANoptosis in HIV Tat and methamphetamine-mediated neuroinflammationNIHNational Institute on Drug Abuse2024 to 2025$1,023,771July 1, 2024April 30, 2029PERIYASAMY, PALSAMYreporter.nih.gov
Serotonin receptors that potentiate addiction-related behavioral and molecular effects induced by methylphenidate plus SSRI exposureNIHNational Institute on Drug Abuse2021 to 2023$1,013,596April 1, 2019January 31, 2024STEINER, HEINZreporter.nih.gov
Effects of methamphetamine use on risk behavior, systemic and mucosal inflammation, and sexually transmitted infection (STI)/HIV risk among men who have sex with menNIHNational Institute on Drug Abuse2021 to 2025$1,011,960July 15, 2021June 30, 2027BLAIR, CHERIE SAVINEreporter.nih.gov
Transgenerational Inheritance of a Cocaine Resistance PhenotypeNIHNational Institute on Drug Abuse2021 to 2022$1,009,002April 1, 2012January 31, 2023PIERCE, ROBERT CHRISTOPHERreporter.nih.gov
Investigations into 5-HT2A signaling mechanisms of psychedelic drugs for the treatment of stimulant use disorderNIHNational Institute on Drug Abuse2024 to 2025$989,771May 15, 2024March 31, 2029MCCORVY, JOHN Dreporter.nih.gov
Brain endothelial EVs role in the neuropathology of drugs of abuse and HIVNIHNational Institute on Drug Abuse2021 to 2022$987,280September 30, 2018June 30, 2023RAMIREZ, SERVIO HEYBERTreporter.nih.gov
Impacts of Recreational Marijuana Legalization and Retail Outlets in Washington: Unique Perspectives from Survey and County Mortality DataNIHNational Institute on Drug Abuse2021 to 2022$986,098July 1, 2019May 31, 2024KERR, WILLIAM C.reporter.nih.gov
The Genetic and Epigenetic Interplay of Cocaine Addiction: A Cell-Type, Circuitry, and Functional DissectionNIHNational Institute on Drug Abuse2024 to 2025$984,000August 1, 2024June 30, 2029ZHANG, ZHUZHUreporter.nih.gov
In situ spatial characterization of CNS HIV-host cellular interactions from victims of sudden deathNIHNational Institute on Drug Abuse2024 to 2025$983,744September 30, 2024July 31, 2027HENRICH, TIMOTHY JENSENreporter.nih.gov
Cyclic Peptides to Treat Cocaine Use DisorderNIHNational Institute of Neurological Disorders and Stroke2024$981,998May 15, 2023April 30, 2026ALDRICH, JANE Vreporter.nih.gov
Glutide for Ending MethamphetamineNIHNational Institute on Drug Abuse2025$977,129September 1, 2025August 31, 2027COFFIN, PHILLIP Oreporter.nih.gov
Differential Roles of Prefrontal Cortical Interneurons in Drug Seeking after WithdrawalNIHNational Institute on Drug Abuse2024 to 2025$972,206July 1, 2024April 30, 2029LIM, BYUNGKOOKreporter.nih.gov
Decoding ensemble dynamics from cortico-amygdalar circuits during social choiceNIHNational Institute of Mental Health2023 to 2025$965,142August 1, 2023July 31, 2028ALLSOP, AZA STEPHENreporter.nih.gov
Hypocretinergic control of cocaine abuseNIHNational Institute on Drug Abuse2021 to 2022$964,962September 30, 2018June 30, 2023HORVATH, TAMAS Lreporter.nih.gov
Drug Abuse and Related Health Disparities: An Intergenerational Longitudinal Study of Offspring of Delinquent Youth (Northwestern Offspring Project)NIHNational Institute on Drug Abuse2021 to 2022$961,334September 1, 2018May 31, 2025TEPLIN, LINDA Areporter.nih.gov
Regulation of monoamine neurons by delta glutamate receptorsNIHNational Institute on Drug Abuse2024 to 2025$961,242April 1, 2024January 31, 2029GANTZ, STEPHANIE C.reporter.nih.gov
Optimization of novel thioesters as a therapeutic strategy for combating opioid overdoses and abuseNIHNational Institute on Drug Abuse2021 to 2022$956,514September 1, 2020July 31, 2023LEWIS, STEPHEN JOHNreporter.nih.gov
Epitranscriptomic Regulation of Synaptic Responses to Drugs of AbuseNIHNational Institute on Drug Abuse2021 to 2022$954,795July 15, 2018June 30, 2024MEYER, KATHRYN Dreporter.nih.gov
Getting Off: A Theory-based mHealth Intervention for Methamphetamine-using MSMNIHNational Institute on Drug Abuse2021 to 2022$953,199July 15, 2018April 30, 2024REBACK, CATHY Jreporter.nih.gov
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency managementNIHNational Institute on Drug Abuse2021 to 2025$947,005April 1, 2021March 31, 2026LI, MICHAEL JONATHANreporter.nih.gov
Cyclic Peptides to Treat Cocaine Use DisorderNIHNational Institute of Neurological Disorders and Stroke2023$945,491May 15, 2023April 30, 2024ALDRICH, JANE Vreporter.nih.gov
Deep Analysis of Transcriptome to Understand the Genetics of Substance Use Disorders in RatsNIHNational Institute on Drug Abuse2025$944,888July 1, 2025March 31, 2030MOHAMMADI, PEJMANreporter.nih.gov
The ION+EMI Study: Intermittent Oral Naltrexone enhanced with an Ecological Momentary Intervention for Methamphetamine-using MSMNIHNational Institute on Drug Abuse2021 to 2023$944,445September 1, 2021July 31, 2025SANTOS, GLENN-MILOreporter.nih.gov
Mentoring patient-oriented research on the health consequences of polydrug useNIHNational Institute on Drug Abuse2021 to 2025$941,480July 1, 2015June 30, 2027RILEY, ELISE D.reporter.nih.gov
Extensive drug histories result in compulsive appetite: functional identification of punishment-reactive neural network re-organization in the rostromedial tegmental nucleusNIHNational Institute on Drug Abuse2024 to 2025$939,600July 15, 2024June 30, 2027SUTO, NOBUYOSHIreporter.nih.gov
Cocaine Abstinence or Reduced Use May Retard Alterations in Brain Structure and Function, and Associated Cognitive Changes among African American Cocaine Users with HIVNIHNational Institute on Drug Abuse2024$939,459May 1, 2024February 28, 2029LAI, SHENGHANreporter.nih.gov
Molecular Pathways of Innate Immunity and Substance Abuse in NeuroHIVNIHNational Institute on Drug Abuse2023 to 2024$927,683September 30, 2023July 31, 2025INACIO MAMEDE, JOAO FILIPEreporter.nih.gov
Transcutaneous Phrenic Nerve Stimulation for Treating Opioid OverdoseNIHNational Institute on Drug Abuse2023$927,319September 1, 2023August 31, 2025LEVIN, HOWARDreporter.nih.gov
Characterization of cocaine induced signaling pathways that enhances HIV transcriptionNIHNational Institute on Drug Abuse2021 to 2023$916,120September 1, 2017April 30, 2026TYAGI, MUDITreporter.nih.gov
Toward Repurposing a Commonly-Used Medication for the Treatment of Pediatric Severe ObesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$914,862August 15, 2023June 30, 2027FOX, CLAUDIA Kreporter.nih.gov
Examination of epigenetic spatial architecture in the CNS as a method to understand cocaine relapse in ecoHIV infected miceNIHNational Institute on Drug Abuse2024 to 2025$908,940September 30, 2024November 30, 2026KLASE, ZACHARY ALANreporter.nih.gov
SCH: Multidimensional Data Science Approach: Measuring and Characterizing Craving and Affective Profiles in Substance Use DisordersNIHNational Institute on Drug Abuse2023 to 2025$900,000August 1, 2023June 30, 2027SANO, AKANEreporter.nih.gov
Cannabinoid inhibition of CNS inflammasome activation via modulation of the gut-brain axisNIHNational Institute on Drug Abuse2025$898,025April 15, 2025February 28, 2030BYRAREDDY, SIDDAPPA Nreporter.nih.gov
Chemokine CXCL12/CXCR4 system and synthetic cathinonesNIHNational Institute on Drug Abuse2021 to 2022$894,344July 1, 2018April 30, 2024RAWLS, SCOTT M.reporter.nih.gov
High-throughput identification and characterization of conserved regulators of drug-induced plasticity using single-neuron resolution atlases of the complete Caenorhabditis elegans nervous systemNIHNational Institute on Drug Abuse2024 to 2025$891,000September 30, 2024July 31, 2029SUN, HAOSHENGreporter.nih.gov
Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSMNIHFogarty International Center2022 to 2024$884,507January 1, 2020June 30, 2026SHRESTHA, ROMANreporter.nih.gov
Elucidating Ih Biophysical Epigenetic Modifications in VTA Dopaminergic Neurons after Contingent and Non-Contingent Cocaine AdministrationNIHNational Institute of General Medical Sciences2022 to 2025$884,337July 15, 2022June 30, 2027JIMENEZ-RIVERA, CARLOS Areporter.nih.gov
Investigating Parkin-mediated Neuronal Energy Maintenance in Methamphetamine Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$881,915September 30, 2023June 30, 2028MOSZCZYNSKA, ANNAreporter.nih.gov
Retinoic acid signaling: a novel factor for addiction-related behaviorNIHNational Institute on Drug Abuse2021 to 2022$864,126September 15, 2018June 30, 2024GREEN, THOMAS ARTHURreporter.nih.gov
Patient Navigator plus Remote mHealth Adherence Support with Incentives: Understanding Criminal Justice EffectsNIHNational Institute on Drug Abuse2022 to 2023$841,820September 30, 2023September 29, 2024TSUI, JUDITHreporter.nih.gov
Assessing central muscarinic acetylcholine type-1 receptors in cocaine use disorder with 11C-LSN3172176.NIHNational Institute on Drug Abuse2022 to 2023$837,270April 15, 2022June 30, 2024WORHUNSKY, PATRICK Dreporter.nih.gov
Cognitively-enhanced tDCS of the dorsolateral prefrontal cortex to reduce craving in cocaine addictionNIHNational Institute on Drug Abuse2025$833,825May 1, 2025February 28, 2030GOLDSTEIN, RITA Zreporter.nih.gov
Role of prelimbic cortical endocannabinoid signaling in enhanced cocaine-seeking behavior following combined repeated stress and cocaine use in ratsNIHNational Institute on Drug Abuse2024 to 2025$832,475March 1, 2024January 31, 2029MCREYNOLDS, JAYME ROSEreporter.nih.gov
Expanding the Scope and Usability of Fast Voltammetric MeasurementsNIHNational Institute on Drug Abuse2024 to 2025$832,134September 15, 2024July 31, 2029SOMBERS, LESLIE Areporter.nih.gov
Cue Reactivity Modulation in MSM with Methamphetamine Use DisorderNIHNational Institute on Drug Abuse2023 to 2024$827,884September 30, 2023March 21, 2025PARVAZ, MUHAMMAD ADEELreporter.nih.gov
The Sex-specific Roles and Neural Processing Correlates of Future Outcome Estimation in the Drug Addiction ProcessNIHNational Institute on Drug Abuse2021 to 2022$822,627July 1, 2018April 30, 2024JAMES, GEORGE ANDREWreporter.nih.gov
B1 noradrenergic blockade in early withdrawal to reduce cocaine induced behavioral flexibility deficitNIHNational Institute on Drug Abuse2021 to 2022$818,813March 1, 2020February 29, 2024WEST, ELIZABETH Areporter.nih.gov
Short-term Outcome of Stimulant Use Disorder Treatment TrialsNIHNational Institute on Drug Abuse2022 to 2023$818,750August 1, 2022January 31, 2024MOJTABAI, RAMINreporter.nih.gov
Basolateral amygdala dopamine in addiction-related learning strategiesNIHNational Institute on Drug Abuse2024 to 2025$818,513September 15, 2024May 31, 2029SAUNDERS, BENJAMIN THOMASreporter.nih.gov
Development and Validation of a Stimulant Use Disorder Severity ScaleNIHNational Institute on Drug Abuse2025$818,486July 15, 2025June 30, 2027KILUK, BRIAN D.reporter.nih.gov
Cognitive Reappraisal for Mitigating Incubation of Cocaine Cue-ReactivityNIHNational Institute on Drug Abuse2023$815,875September 30, 2023August 31, 2028PARVAZ, MUHAMMAD ADEELreporter.nih.gov
Development of therapeutic candidates for stimulant use disorder using AI-driven platform for focused drug discovery and accelerated developmentNIHNational Institute on Drug Abuse2025$811,876July 15, 2025July 31, 2028VARSHNEY, JYOTIKAreporter.nih.gov
Strength in HEALing: Indigenous Community-Led Strategies to Treat Stimulant UseNIHNational Institute on Drug Abuse2024$809,042September 30, 2024August 31, 2026HIRCHAK, KATHERINEreporter.nih.gov
Computational Methods for Identification of Genetic Factors Affecting the Response to Drug AbuseNIHNational Institute on Drug Abuse2021 to 2022$807,872September 1, 2017June 30, 2023PELTZ, GARY Areporter.nih.gov
Methamphetamine and Cysteinyl Leukotrienes in HIV PersistenceNIHNational Institute on Drug Abuse2025$804,728June 1, 2025April 30, 2030KAUL, MARCUSreporter.nih.gov
Together Against Overdose: community developed technology to encourage drug checking, distribution of harm reduction supplies, and linkage to servicesNIHNational Institute on Drug Abuse2024$803,573September 30, 2024August 31, 2026ARONSON, IAN DAVIDreporter.nih.gov
Genetic substrates of cue-reactivity and cocaine motivationNIHNational Institute on Drug Abuse2025$802,735August 1, 2025April 30, 2030MEYER, PAUL Jreporter.nih.gov
Developing nonmuscle myosin II inhibitors for the treatment of glioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$802,521January 1, 2021December 31, 2024MILLER, COURTNEY Areporter.nih.gov
Methamphetamine, HIV integration and latency in the brainNIHNational Institute on Drug Abuse2025$798,422September 30, 2023August 31, 2028MARCONDES, MARIA CECILIA GARIBALDIreporter.nih.gov
Discovery of GPR52 ligand probes for cocaine use disorderNIHNational Institute on Drug Abuse2025$795,090September 1, 2025May 31, 2030ALLEN, JOHN Areporter.nih.gov
Role of miRNAs in Methamphetamine/HIV-mediated Immune ActivationNIHNational Institute on Drug Abuse2021 to 2022$792,500April 1, 2018February 29, 2024HO, WENZHEreporter.nih.gov
Reversing Cocaine-induced Impairments in the NAc with Controllable StressorsNIHNational Institute on Drug Abuse2021 to 2022$782,589September 30, 2018August 31, 2024SADDORIS, MICHAELreporter.nih.gov
Interplay between limbic norepinephrine and dopamine circuits in reward and aversionNIHNational Institute on Drug Abuse2025$781,032August 1, 2025April 30, 2030PARK, JINWOOreporter.nih.gov
Novel anti-cocaine D1 partial agonistsNIHNational Institute on Drug Abuse2021 to 2022$780,000May 1, 2019April 30, 2024HARDING, WAYNE WESLEYreporter.nih.gov
Analyzing Sequential, Multiple Assignment, Randomized Trials in the Presence of Partial ComplianceNIHNational Institute on Drug Abuse2021 to 2022$769,466September 30, 2019August 31, 2024ERTEFAIE, ASHKANreporter.nih.gov
Addiction liability, poor attentional control, and cholinergic deficiencyNIHNational Institute on Drug Abuse2021 to 2022$768,539September 15, 2018June 30, 2023SARTER, MARTIN Freporter.nih.gov
THE ROLE OF RYANODINE RECEPTORS IN DRUG SEEKINGNIHNational Institute on Drug Abuse2021 to 2022$767,162July 15, 2018May 31, 2024RIEGEL, ARTHUR Creporter.nih.gov
Supporting Treatment Adherence for Resilience and Thriving (START): A mHealth intervention to improve ART adherence for HIV-positive stimulant-using menNIHNational Institute on Drug Abuse2023$762,759August 1, 2023July 31, 2025CARRICO, ADAM WAYNEreporter.nih.gov
Cocaine Addition and the Need-State HypothesisNIHNational Institute on Drug Abuse2025$762,063May 1, 2025February 28, 2030GRIGSON, PATRICIA SUEreporter.nih.gov
Our Healing Journey: A Cultural and Traditional Response to the Opioid EpidemicNIHNational Institute on Drug Abuse2024 to 2025$759,957August 15, 2024July 31, 2026WEBB, KELLIEreporter.nih.gov
NOP receptors as targets for novel pharmacotherapies for cocaine use disorder in nonhuman primate modelsNIHNational Institute on Drug Abuse2025$758,218September 1, 2025May 31, 2030CZOTY, PAUL W.reporter.nih.gov
Concussion and Attention-Deficit/Hyperactivity Disorder: Investigating the relationship between cognitive outcome, prescription stimulants, and functional MRI biomarkers in the ABCD study.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$758,064April 1, 2022March 31, 2027KAY, BENJAMIN PAULreporter.nih.gov
Addressing negative social experiences through coping and resilience to reduce methamphetamine use and improve PrEP cascade progression among Latino MSMNIHNational Institute on Drug Abuse2022 to 2025$754,144September 1, 2022August 31, 2027ALGARIN, ANGEL Breporter.nih.gov
Identification of Neural Markers of Aggression and Irritability and Their Capacity to Predict Treatment Response to CNS Stimulant Medication in Youth with ADHDNIHNational Institute of Mental Health2025$752,854June 1, 2025May 31, 2030WAXMONSKY, JAMES GAIERreporter.nih.gov
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and CocaineNIHNational Institute on Drug Abuse2024 to 2025$751,970August 15, 2021June 30, 2027GUO, MINGLEIreporter.nih.gov
The Role of HIV Proteins in Psychostimulant AbuseNIHNational Institute on Drug Abuse2025$751,112May 1, 2025March 31, 2030GALLI, AURELIOreporter.nih.gov
Cucurbituril Type Receptors as Sequestration Agents for Drugs of AbuseNIHNational Institute of General Medical Sciences2021 to 2022$747,910April 15, 2019January 31, 2024ISAACS, LYLE Dreporter.nih.gov
Role of Class IIa HDAC Target Genes in Opioid and Cocaine AddictionNIHNational Institute on Drug Abuse2021 to 2022$747,500July 1, 2013May 31, 2024COWAN, CHRISTOPHER Wreporter.nih.gov
The protective effect of volitional social interaction on drug addictionNIHNational Institute on Drug Abuse2021 to 2023$747,000May 1, 2021April 30, 2025VENNIRO, MARCOreporter.nih.gov
Leveraging Functional Selectivity in the Neurotensin Receptor 1-Mediated Treatment of AddictionNIHNational Institute on Drug Abuse2022 to 2024$747,000June 15, 2019December 31, 2024SLOSKY, LAUREN Mreporter.nih.gov
Sex Differences in AddictionNIHNational Institute on Drug Abuse2022 to 2024$747,000March 1, 2019February 28, 2026KOHTZ, AMYreporter.nih.gov
Role of orexin receptors in the abuse- and sleep-related effects of methamphetamineNIHNational Institute on Drug Abuse2022 to 2024$747,000August 1, 2020July 31, 2026BERRO, LAIS Freporter.nih.gov
Effects of exercise on dopaminergic mechanisms of cocaine relapseNIHNational Institute on Drug Abuse2022 to 2024$746,997August 1, 2019February 28, 2026ZLEBNIK, NATALIEreporter.nih.gov
Circuit Mechanisms for Conditioned Stress Regulation of AddictionNIHNational Institute on Drug Abuse2022 to 2024$746,997July 15, 2019June 30, 2026GARCIA KELLER, CONSTANZAreporter.nih.gov
Reducing co-occurring substance use and HIV risk among stimulant-using men at high risk for HIV in the United States of America.NIHNational Institute on Drug Abuse2023 to 2025$746,997June 1, 2021May 31, 2027COLON-BURGOS, JOSE FELIXreporter.nih.gov
Orexin (hypocretin) signaling in ventral tegmental area as a common mediator of sleep disturbances and drug demand in cocaine abstinenceNIHNational Institute on Drug Abuse2024 to 2025$745,734July 15, 2024May 31, 2029ASTON-JONES, GARY S.reporter.nih.gov
Neural circuitry of distress toleranceNIHNational Institute on Drug Abuse2021 to 2023$745,315March 1, 2019February 28, 2025MOSCHAK, TRAVIS Mreporter.nih.gov
Role of Nucleus Accumbens D2-expressing Neurons in Punished Cocaine SeekingNIHNational Institute on Drug Abuse2021 to 2023$744,648April 1, 2019April 30, 2025VENTO, PETER J.reporter.nih.gov
Multimodal profiling of microglia during HIV infection and substance use disorderNIHNational Institute on Drug Abuse2025$744,484September 30, 2023August 31, 2028JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Hypocretin/Orexin Regulation of Dopamine Signaling and Cocaine ReinforcementNIHNational Institute on Drug Abuse2021 to 2022$742,144January 1, 2013May 31, 2025ESPAÑA, RODRIGO A.reporter.nih.gov
Improving retention in care for persons with HIV who use substances by increasing acceptance and reducing stigmaNIHNational Institute on Drug Abuse2021 to 2023$736,694June 1, 2021May 31, 2025MOITRA, ETHANreporter.nih.gov
Unpredictable availability as a determinant of drug-related outcomesNIHNational Institute on Drug Abuse2021 to 2022$736,250April 1, 2018March 31, 2025HUSKINSON, SALLYreporter.nih.gov
Molecular Pathways of Innate Immunity and Substance Abuse in NeuroHIVNIHNational Institute on Drug Abuse2025$733,223September 30, 2023July 31, 2028I. MAMEDE, JOAOreporter.nih.gov
Advancing Non-Abstinence Outcomes in the Treatment of Methamphetamine Use DisorderNIHNational Institute on Drug Abuse2025$731,997September 30, 2025May 31, 2030STOOPS, WILLIAM WALTONreporter.nih.gov
Prescription Stimulant Supply Shocks: Assessing the Impacts on Health Outcomes and DisparitiesNIHNational Institute of Mental Health2025$729,367December 18, 2024November 30, 2028SMART, ROSANNAreporter.nih.gov
Augmenting cognitive-behavioral therapy with rTMS of the medial prefrontal and anterior cingulate cortices for the treatment of cocaine use disorderNIHNational Institute on Drug Abuse2023$728,927May 15, 2023April 30, 2027MARTINEZ, DIANA Mreporter.nih.gov
Molecular mechanisms: Dysregulation of monoamine transporters by HIV-1Tat and cocaineNIHNational Institute on Drug Abuse2025$728,575May 15, 2025April 30, 2029ZHU, JUNreporter.nih.gov
Training in MHealth Prevention with MSMNIHNational Institute on Drug Abuse2021 to 2024$725,604July 15, 2020June 30, 2026SHRESTHA, ROMANreporter.nih.gov
Intervention to Reduce Internalized Stigma (IRIS) among People Living with HIV who use SubstancesNIHNational Institute on Drug Abuse2022 to 2024$724,401September 1, 2022July 31, 2026FLETCHER, JESSE BRADFORDreporter.nih.gov
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaineNIHNational Institute on Drug Abuse2021 to 2022$724,376September 30, 2018July 31, 2025BUCH, SHILPA J.reporter.nih.gov
Adaption of the STAIR-NT Trauma Intervention for Polysubstance PopulationsNIHNational Institute on Drug Abuse2022$723,155September 30, 2022September 29, 2025BUNTING, AMANDA Mreporter.nih.gov
A longitudinal analysis of methamphetamine use, social relationships, and cognitive function among people living with HIVNIHNational Institute on Drug Abuse2021 to 2024$720,272September 30, 2021July 31, 2026BENDER, ALEXIS ANNEreporter.nih.gov
Oxytocin and drug extinction in prairie volesNIHNational Institute on Drug Abuse2025$718,146August 15, 2025April 30, 2030KABBAJ, MOHAMEDreporter.nih.gov
Transporting treatment effects from clinical trials to real-world populations with co-occurring opioid and stimulant use disordersNIHNational Institute on Drug Abuse2022 to 2025$714,130July 1, 2022June 30, 2027COOK, RYANreporter.nih.gov
Virtual Reality-Augmented Future Orientation in Stimulant Use Disorder RecoveryNIHNational Institute on Drug Abuse2022 to 2024$713,250May 1, 2022April 30, 2026OBERLIN, BRANDONreporter.nih.gov
The Mechanistic Role of Visual Areas at the Interaction of Social Behavior and Drug Effects in Nonhuman PrimatesNIHNational Institute on Drug Abuse2025$712,500September 1, 2025May 31, 2030PONCE, CARLOS RAMONreporter.nih.gov
Cortical Plasticity in Methamphetamine AddictionNIHNational Institute on Drug Abuse2021 to 2022$710,126September 15, 2012June 30, 2024SCOFIELD, MICHAEL DAVIDreporter.nih.gov
Repurposing Semaglutide for the Treatment of Cocaine Use Disorder: a Pilot Mechanistic StudyNIHNational Institute on Drug Abuse2025$702,965June 15, 2025February 28, 2029YAMMINE, LUBAreporter.nih.gov
Effect of Mindfulness Training on Opioid Use and Anxiety During Primary Care Buprenorphine TreatmentNIHNational Center for Complementary & Integrative Health2022$700,000July 1, 2022August 31, 2024SCHUMAN OLIVIER, ZEV DAVIDreporter.nih.gov
Genetic Factors Underlying Risk for Methamphetamine Intake and Associated TraitsNIHNational Institute on Drug Abuse2021 to 2022$693,986September 30, 2018July 31, 2024PHILLIPS, TAMARA J.reporter.nih.gov
Relevance and plasticity of inhibitory metabotropic signaling in reward circuitsNIHNational Institute on Drug Abuse2021 to 2022$688,500August 1, 2013February 28, 2023WICKMAN, KEVIN Dreporter.nih.gov
Applying a multiple methods approach to examine spatial and temporal variability in a state's illicit drug marketNIHNational Institute on Drug Abuse2025$688,271June 1, 2025February 28, 2030HEIMER, ROBERTreporter.nih.gov
Combined mGluR5 PET and fMRI imaging of Sex Differences during Cocaine WithdrawalNIHNational Institute on Drug Abuse2022$685,732June 1, 2017March 31, 2025MCCAUL, MARY Ereporter.nih.gov
Social Influences on Drug-Seeking BehaviorNIHNational Institute on Drug Abuse2021 to 2022$685,534April 1, 2012July 31, 2025SMITH, MARK Areporter.nih.gov
Neuron subtype specific role of DNA methylcytosine dioxygenase TET1 in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2022$681,815September 15, 2018June 30, 2024FENG, JIANreporter.nih.gov
Defining molecular mechanisms by which stimulant evoked dopamine drives inflammation and neuronal dysfunction in neuroHIVNIHNational Institute on Drug Abuse2025$677,147July 1, 2023June 30, 2028GASKILL, PETER JESSEreporter.nih.gov
Neural Mechanisms underlying dissociable effects of cTBS in Psychostimulant AbuseNIHNational Institute on Drug Abuse2025$674,709July 15, 2025April 30, 2030FROELIGER, BRETTreporter.nih.gov
Screening and Brief Intervention for Prescription Stimulant Misuse and Diversion: Refining and Piloting a Curriculum for College Health ProvidersNIHNational Institute on Drug Abuse2023 to 2025$672,656July 15, 2023May 31, 2027BAVARIAN, NILOOFARreporter.nih.gov
Development of selective cannabinoid receptor 2 agonists for treatment of addictionNIHNational Institute of Neurological Disorders and Stroke2022$661,980April 19, 2022March 31, 2023SHAMLOO, MEHRDADreporter.nih.gov
RESTORE (Recovery and Engagement for STimulant users On Re-entry)NIHNational Institute on Drug Abuse2025$660,104August 15, 2025July 31, 2027NIJHAWAN, ANK ELISABETHreporter.nih.gov
Estradiol signaling pathways mediating sex differences in striatal synaptic plasticityNIHNational Institute on Drug Abuse2023$652,413April 15, 2023August 11, 2023BLACKWELL, KIM Lreporter.nih.gov
The Influence of Gonadal Hormones on Opioid UseNIHNational Institute on Drug Abuse2021 to 2022$651,443September 30, 2018July 31, 2024SMITH, MARK Areporter.nih.gov
The role of GPER-1 and addictionNIHNational Institute on Drug Abuse2021 to 2022$649,193September 30, 2020July 31, 2024BECKER, JILL B.reporter.nih.gov
Long-acting aldicarb hydrolase as a medical countermeasure for aldicarb poisoningNIHNational Institute of Neurological Disorders and Stroke2025$643,949September 1, 2023August 31, 2028ZHENG, FANGreporter.nih.gov
Psilocybin-Assisted Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2025$643,019July 15, 2025June 30, 2027ARIAS, ALBERT JOSEPHreporter.nih.gov
Advancing Troriluzole as a Treatment for Methamphetamine Use Disorder: A Human Laboratory StudyNIHNational Institute on Drug Abuse2025$634,048April 15, 2025February 28, 2029STOOPS, WILLIAM WALTONreporter.nih.gov
ADHD and Sleep: Evaluating the Impact of Drug-Drug and Drug-Disease Interactions to Inform CareNIHNational Institute of Mental Health2025$633,671May 1, 2025February 28, 2030BUSHNELL, GRETAreporter.nih.gov
Behavioral Safety and Fentanyl Education: BSAFENIHNational Institute on Drug Abuse2025$629,866September 30, 2025May 31, 2030COFFIN, PHILLIP Oreporter.nih.gov
HIV and Cocaine Use Leads to Loss of Astrocyte Neurotrophic Support and Impaired Lipid Homeostasis in the BrainNIHNational Institute of Neurological Disorders and Stroke2025$627,502September 20, 2022May 31, 2027LANGFORD, DIANNE TERESAreporter.nih.gov
Targeting Immune Inflammation in Cocaine Use Disorder: A Human Laboratory Study with PentoxifyllineNIHNational Institute on Drug Abuse2025$620,383July 1, 2025February 29, 2028STOOPS, WILLIAM WALTONreporter.nih.gov
Data Mining and Functional Validation of SCORCH DatasetsNIHNational Institute on Drug Abuse2025$608,652September 1, 2025May 31, 2030SANNA, PIETRO Preporter.nih.gov
Midcareer K24 Award for Mentoring and Patient-Oriented ResearchNIHNational Institute on Drug Abuse2023 to 2025$602,500February 1, 2023January 31, 2028COFFIN, PHILLIP Oreporter.nih.gov
Modeling weekly and daily processes of a high-risk feedback cycle of alcohol, cannabis, and nonmedical use of prescription stimulants in college students: Impacts on use, academics, and sleepNIHNational Institute on Drug Abuse2025$589,440May 15, 2025February 28, 2030FAIRLIE, ANNE MARIEreporter.nih.gov
Norepinephrine modulates medial prefrontal cortex neural ensembles that control cocaine seeking behaviorNIHNational Institute on Drug Abuse2022 to 2025$586,321December 12, 2022May 31, 2027GHEIDI, ALIreporter.nih.gov
Cell-Types Specific Neuroadaptations in the Nucleus Accumbens Shell Associated with Individual Differences in Cocaine-SeekingNIHNational Institute on Drug Abuse2021 to 2023$580,446September 30, 2021September 2, 2023CARRERO, JEFFREY PARRILLAreporter.nih.gov
Chromatin regulation of neuronal activity-induced enhancer priming and epigenetic memoryNIHNational Institute of Neurological Disorders and Stroke2025$578,632March 1, 2025December 31, 2029WU, JIANGreporter.nih.gov
Understanding the role of paraventricular neurotensin neurons in valence processingNIHNational Institute on Drug Abuse2024 to 2025$577,653February 1, 2022January 31, 2027LI, HAOreporter.nih.gov
Hybrid Trial of Peer-Supported Affect Regulation and Contingency Management to Improve HIV Prevention Outcomes in the Southern United StatesNIHNational Institute on Drug Abuse2025$575,433August 1, 2025July 31, 2027LANCASTER, KATHRYN ELIZABETHreporter.nih.gov
Cardiovascular, Immune and Psychosocial Benefits of Reduced Cocaine UseNIHNational Institute on Drug Abuse2022$574,367September 1, 2017November 30, 2024STOOPS, WILLIAM WALTONreporter.nih.gov
A Forward Genetic Screen to Identify Genes Involved in Amphetamine ActionNIHNational Institute on Drug Abuse2025$571,675May 15, 2025April 30, 2028CARVELLI, LUCIAreporter.nih.gov
TASK ORDER 01 COCAINE INTERACTION SAFETY STUDIES IN RATS. TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS IDIQ. ORDERING PERIOD: 09/12/2023 - 09/11/2024. NIDA REF. NO. N01DA-23-8939NIHNational Institute on Drug Abuse2023$571,190September 12, 2023September 11, 2024AROLFO , MARIAreporter.nih.gov
HIV and Cocaine Drive Bone-Marrow Blood (BMB) Barrier Dysfunction and Altered Hematopoietic Stem Cell (HSC) Differentiation Leading to Cardiovascular DiseaseNIHNational Institute on Drug Abuse2022$570,030April 1, 2022October 26, 2023ANDREWS, ALLISON MICHELLEreporter.nih.gov
Leveraging Networks, Epidemiology, and Epidemic Modeling: Creative Approaches for HIV EliminationNIHNational Institute on Drug Abuse2021 to 2023$568,491August 15, 2019July 31, 2025SKAATHUN, BRITTreporter.nih.gov
Nucleus accumbens neuronal ensembles in drugs and natural rewards seeking.NIHNational Institute on Drug Abuse2021 to 2023$564,842December 1, 2020August 16, 2023BATCHELDER, ABIGAILreporter.nih.gov
HIV and cocaine mediated lipid dysregulation in microglia: Immunometabolism mechanisms underlying NeuroHIVNIHNational Institute on Drug Abuse2025$563,742July 15, 2025May 31, 2030GUO, MINGLEIreporter.nih.gov
The role of neuronal ensemble Rac1 activity in cocaine seeking behaviorNIHNational Institute on Drug Abuse2024$563,694July 15, 2024April 30, 2025WARREN, BRANDON Lreporter.nih.gov
MRI data fusion to investigate effects of drug abuse on HIV neurological complicationsNIHNational Institute on Drug Abuse2021 to 2022$556,750March 15, 2018June 30, 2023MEADE, CHRISTINA Sreporter.nih.gov
Mentoring clinician scientists in patient-oriented substance use disorder researchNIHNational Institute on Drug Abuse2023 to 2025$554,316June 15, 2023May 31, 2028SAKAI, JOSEPH Treporter.nih.gov
Chemokine Receptor Antagonists (CRAs): Characterization in Preclinical Models of Methamphetamine Use DisorderNIHNational Institute on Drug Abuse2025$552,629July 1, 2025March 31, 2030RAWLS, SCOTT M.reporter.nih.gov
Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$547,813July 1, 2023June 30, 2028WEBBER, HEATHER Ereporter.nih.gov
The role of neuroactive steroids in stress, drug craving and drug use in cocaine use disordersNIHNational Institute on Drug Abuse2021 to 2023$547,788February 1, 2019January 31, 2025MILIVOJEVIC, VERICAreporter.nih.gov
Unhealthy alcohol use, other drug use, and mental health disorders: comorbidity burden in people with HIV, gaps in treatment, and impact on the HIV care continuumNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$535,104September 25, 2019August 31, 2025LESKO, CATHERINEreporter.nih.gov
Impact of miRNAs on adult neurogenesis following exposure to methamphetamine and HIV-1 InfectionNIHNational Institute on Drug Abuse2024 to 2025$529,515April 1, 2024March 31, 2027PARK, MIN SEONreporter.nih.gov
Local labor market contexts and substance use in young and middle adulthood: Using agent-based modeling to guide substance use prevention strategiesNIHNational Institute on Drug Abuse2023 to 2025$524,091July 1, 2023June 30, 2028OH, SEHUNreporter.nih.gov
Defining the role of cortical circuit dynamics in learning and addictionNIHNational Institute on Drug Abuse2021 to 2022$514,599March 1, 2020February 28, 2023SICILIANO, CODYreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Ut Southwestern Medical CenterDallas, TX4$46.2 million0$0
University of California, San DiegoLa Jolla, CA22$40.4 million0$0
University of Miami School of MedicineCoral Gables, FL9$37 million0$0
Intervexion Therapeutics, LLCLittle Rock, AR4$34.6 million0$0
Yale UniversityNew Haven, CT20$32.8 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY17$27.5 million0$0
Johns Hopkins UniversityBaltimore, MD11$27.1 million0$0
University of California, San FranciscoSan Francisco, CA15$24.4 million0$0
University of KentuckyLexington, KY15$23.4 million0$0
Clear Scientific, LLCCambridge, MA5$23.3 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN1$22.4 million0$0
Wake Forest University Health SciencesWinston-Salem, NC21$21 million0$0
University of California Los AngelesLos Angeles, CA8$19.8 million0$0
University of CincinnatiCincinnati, OH3$19.5 million0$0
Virginia Commonwealth UniversityRichmond, VA19$19.4 million0$0
University of Maryland BaltimoreBaltimore, MD12$19.4 million0$0
Oregon Health & Science UniversityPortland, OR15$19.3 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA14$17.6 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA15$17 million0$0
University of PennsylvaniaPhiladelphia, PA8$16.9 million0$0
University of Alabama at BirminghamBirmingham, AL13$16.3 million0$0
Allen InstituteSeattle, WA1$14.5 million0$0
Medical University of South CarolinaCharleston, SC16$14 million0$0
Scripps Research Institute, theLa Jolla, CA8$13.9 million0$0
University of WashingtonSeattle, WA8$13.3 million0$0
University of FloridaGainesville, FL15$13 million0$0
University of Texas Med BR GalvestonGalveston, TX7$12.8 million0$0
Broad Institute, Inc.Cambridge, MA1$12.6 million0$0
University of Michigan at Ann ArborAnn Arbor, MI10$12.5 million0$0
Jackson LaboratoryBar Harbor, ME4$11.3 million0$0
Emory UniversityAtlanta, GA7$11.1 million0$0
Graduate School of Public Health and Health PolicyNew York, NY3$10.8 million0$0
Research Triangle InstituteResearch Triangle Park, NC5$10.7 million0$0
Florida International UniversityMiami, FL5$10.3 million0$0
University of ChicagoChicago, IL6$10.1 million0$0
University of Nebraska Medical CenterOmaha, NE9$9.8 million0$0
Phoenix Pharmalabs, Inc.Woodscross, UT2$9 million0$0
University of MinnesotaMinneapolis, MN15$9 million0$0
Ohio State UniversityColumbus, OH6$8.9 million0$0
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INCNew York, NY7$8.6 million0$0
Stanford UniversityStanford, CA5$8.4 million0$0
Mclean HospitalBelmont, MA5$8.2 million0$0
Drexel UniversityPhiladelphia, PA11$7.7 million0$0
Biocorrx Pharmaceuticals INCAnaheim, CA1$7.4 million0$0
Medical College of WisconsinMilwaukee, WI8$7.3 million0$0
Northwestern University at ChicagoChicago, IL7$7.2 million0$0
Sparian Biosciences, Inc.New York City, NY1$6.9 million0$0
Rush University Medical CenterChicago, IL4$6.9 million0$0
Chestnut Health Systems, Inc.Bloomington, IL4$6.8 million0$0
Omeros CorporationSeattle, WA1$6.7 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH2$6.6 million0$0
University of Maryland, College ParkCollege Park, MD5$6.5 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA1$6.4 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX4$6.2 million0$0
University of South Carolina at ColumbiaColumbia, SC6$6.2 million0$0
New York University School of MedicineNew York, NY5$6.1 million0$0
University of Mississippi Med CTRJackson, MS6$5.9 million0$0
Duke UniversityDurham, NC7$5.8 million0$0
University of Colorado DenverAurora, CO6$5.8 million0$0
Vanderbilt UniversityNashville, TN16$5.7 million0$0
University of Texas HLTH Science CenterSan Antonio, TX6$5.6 million0$0
Simon Fraser UniversityBurnaby1$5.3 million0$0
Tempero Bio, Inc.Oakland, CA1$5.3 million0$0
Tonix Pharmaceuticals, Inc.Chatham, NJ1$5.2 million0$0
Public Health Foundation EnterprisesCity Of Industry, CA4$5 million0$0
University of VirginiaCharlottesville, VA3$4.9 million0$0
Brigham and Women's HospitalBoston, MA2$4.8 million0$0
Case Western Reserve UniversityCleveland, OH3$4.7 million0$0
Friends Research Institute, Inc.Baltimore, MD3$4.7 million0$0
Myosin Therapeutics Inc.Jupiter, FL2$4.7 million0$0
Weill Medical Coll of Cornell UnivNew York, NY5$4.7 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ7$4.6 million0$0
Brown UniversityProvidence, RI3$4.5 million0$0
SUNY at BuffaloAmherst, NY5$4.5 million0$0
Public Health InstituteOakland, CA2$4.4 million0$0
University of IowaIowa City, IA5$4.2 million0$0
Seattle Children's HospitalSeattle, WA3$4.1 million0$0
University of California-RiversideRiverside, CA3$4.1 million0$0
Massachusetts General HospitalBoston, MA3$4.1 million0$0
University of RochesterRochester, NY2$3.9 million0$0
Columbia University Health SciencesNew York, NY5$3.8 million0$0
Florida State UniversityTallahassee, FL3$3.8 million0$0
Virogenomics Biodevelopment, Inc.Tigard, OR2$3.7 million0$0
Boston Children's HospitalBoston, MA1$3.7 million0$0
University of Texas at AustinAustin, TX4$3.6 million0$0
University of ConnecticutStorrs, CT4$3.5 million0$0
Lovelace Biomedical Research InstituteAlbuquerque, NM2$3.5 million0$0
Southern Research InstituteBirmingham, AL1$3.4 million0$0
University of California-Santa BarbaraSanta Barbara, CA3$3.3 million0$0
San Diego Biomedical Research InstituteSan Diego, CA3$3.3 million0$0
Trustees of Boston UniversityBoston, MA2$3.2 million0$0
Baylor College of MedicineHouston, TX2$3 million0$0
Meharry Medical CollegeNashville, TN1$3 million0$0
Evon Medics, LLCElkridge, MD1$2.9 million0$0
Georgia State UniversityAtlanta, GA1$2.9 million0$0
University of California-IrvineIrvine, CA4$2.9 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA1$2.8 million0$0
Praeventix, LLCExton, PA1$2.8 million0$0
University of Toledo Health Sci CampusToledo, OH2$2.8 million0$0
University of Kansas Medical CenterKansas City, KS1$2.8 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025394$253,881,5770$0
2024402$231,273,5230$0
2023404$232,190,9840$0
2022419$263,494,8920$0
2021272$177,524,2980$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 4 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 2 awards here
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)RFA-DA-25-060NIHMarch 5, 2027$1.5 millionNotice number printed on 2 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)PAR-24-089NIH93.279November 13, 2026$750,000Same assistance listing 93.279 as 715 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.279November 16, 2026$50,000Same assistance listing 93.279 as 715 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 715 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 715 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIH93.279November 24, 2026Not listedSame assistance listing 93.279 as 715 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.279December 3, 2026Not listedSame assistance listing 93.279 as 715 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.279December 3, 2026Not listedSame assistance listing 93.279 as 715 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.279December 4, 2026Not listedSame assistance listing 93.279 as 715 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.279January 5, 2027Not listedSame assistance listing 93.279 as 715 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.279January 5, 2027Not listedSame assistance listing 93.279 as 715 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.279January 7, 2027$375,000Same assistance listing 93.279 as 715 awards here
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)PAR-25-378NIH93.279January 7, 2027Not listedSame assistance listing 93.279 as 715 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.279January 7, 2027Not listedSame assistance listing 93.279 as 715 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.279January 26, 2027Not listedSame assistance listing 93.279 as 715 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.