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Data / Research funding / Stem Cell Research - Embryonic - Human

Stem Cell Research - Embryonic - Human: 498 NIH awards ($517.8M) to 139 organizations

498 NIH awards ($517.8M) in the NIH spending category Stem Cell Research - Embryonic - Human, to 139 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

498 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
COBRE in Human GeneticsNIHNational Institute of General Medical Sciences2021 to 2025$10,847,075February 10, 2021January 31, 2027MACKAY, TRUDY F.reporter.nih.gov
Center for 3D Structure and Physics of the GenomeNIHNational Human Genome Research Institute2021 to 2024$9,564,360September 18, 2020June 30, 2026DEKKER, JOBreporter.nih.gov
Multiscale Analyses of 4D Nucleome Structure and Function by Comprehensive Multimodal Data IntegrationNIHNational Human Genome Research Institute2021 to 2024$8,301,636September 22, 2020June 30, 2026MA, JIANreporter.nih.gov
Functional Interrogation of T2D-associated genes in human stem cell-derived models and miceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,998,766August 20, 2020June 30, 2025SEALE, PATRICKreporter.nih.gov
Molecular Circuits in the Hematopoietic Stem Cell NicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,422,507August 15, 2020May 31, 2025DALEY, GEORGE Qreporter.nih.gov
The second phase of NIH Common Fund 4D Nucleome Network Organizational HubNIHNational Cancer Institute2021 to 2024$6,160,327March 1, 2024August 31, 2024ZHONG, SHENGreporter.nih.gov
Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes MellitusNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,582,323September 20, 2018July 31, 2024STAHL, ANDREASreporter.nih.gov
Illuminating Function of the Understudied Druggable KinomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,503,990September 15, 2017December 31, 2024JOHNSON, GARY L.reporter.nih.gov
Live-cell multiplex super-resolution imaging of chromatin state transitionsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$4,225,012September 15, 2020June 30, 2026BINTU, LACRAMIOARAreporter.nih.gov
Genome-Wide Discovery and Translational Research for Neural RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,147,990December 1, 2016November 30, 2025STRITTMATTER, STEPHEN Mreporter.nih.gov
Cardiac Lineage-Specific Molecular Mechanisms of Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,682,052February 1, 2021January 31, 2025CHI, NEIL Creporter.nih.gov
Microphysiological systems for modeling autoimmunity in type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,372,768August 2, 2019July 31, 2025STANGER, BEN Zreporter.nih.gov
Enhancer-based Immune and Beta Cell Dysregulation Underlying T1D RiskNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,303,112September 15, 2020June 30, 2025SUH, YOUSINreporter.nih.gov
Identification of the active nuclear niche(s) using novel proteomic, genomic, transgenic, and live-cell microscopy technologiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,283,997September 15, 2020June 30, 2026BELMONT, ANDREW STEVENreporter.nih.gov
Retinal Ganglion Cell Replacement in Optic NeuropathiesNIHNational Eye Institute2021 to 2024$3,242,042September 30, 2018August 31, 2024GOLDBERG, JEFFREY Lreporter.nih.gov
Ex Vivo Generation of Functional Kidney Tissues for TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,161,308September 1, 2020May 14, 2025LEWIS, JENNIFER A.reporter.nih.gov
Modeling diabetes using an integrated plate systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$3,092,998September 20, 2018July 31, 2024WELLS, JAMES Mreporter.nih.gov
ENCODE Mapping Center-A Comprehensive Catalog of DNase I Hypersensitive SitesNIHNational Human Genome Research Institute2021$3,086,945February 1, 2021January 31, 2023STAMATOYANNOPOULOS, JOHN Areporter.nih.gov
Extremely high-throughput mapping of protein, RNA, and chromatin interactions in health and diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,945,203July 30, 2020June 30, 2025ZHONG, SHENGreporter.nih.gov
Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,918,081August 15, 2021July 31, 2026LI, PULINreporter.nih.gov
Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.NIHNational Institute of Mental Health2021 to 2024$2,907,904April 15, 2020January 31, 2026SALAMA, SOFIE REDAreporter.nih.gov
Retinal disease models for translational photoreceptor replacementNIHNational Eye Institute2021 to 2022$2,898,123September 30, 2018May 31, 2025WOLFE, JOHN Hreporter.nih.gov
Higher Precision Human and Mouse TranscriptomesNIHNational Human Genome Research Institute2021$2,888,702February 1, 2017January 31, 2023WOLD, BARBARA Jreporter.nih.gov
Function of NeurexinsNIHNational Institute of Mental Health2021 to 2024$2,855,805September 30, 1994February 28, 2025SUDHOF, THOMAS C.reporter.nih.gov
Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesisNIHNational Institute on Aging2022$2,818,493August 1, 2022July 31, 2025HUANG, TIMOTHY YIKAIreporter.nih.gov
Discovery of diabetes-relevant β cell enhancers through 4D enhancer mapping, integrative analysis, and large-scale CRISPRi perturbation screensNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,792,424September 15, 2020June 30, 2025HUANGFU, DANWEIreporter.nih.gov
Adaptive epigenetic mechanisms of beta and immune cells in autoimmune diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,708,550July 15, 2021June 30, 2025HEROLD, KEVAN Creporter.nih.gov
Transcriptional condensates, epigenetic editing and Rett SyndromeNIHNational Institute of Mental Health2021 to 2023$2,677,396September 15, 2014July 31, 2025JAENISCH, RUDOLFreporter.nih.gov
Molecular pathobiology of soluble TREM2 in Alzheimer's diseaseNIHNational Institute on Aging2023$2,655,773April 1, 2017August 31, 2026HUANG, TIMOTHY YIKAIreporter.nih.gov
Modulating intrinsic beta cell stress to block diabetes pathogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,648,788August 15, 2021June 30, 2025PAPA, FEROZ Rreporter.nih.gov
Defining Characteristics of Cortical Progenitor Cells over Time in Mouse and HumanNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,620,540December 15, 2016November 30, 2025TEMPLE, SALLYreporter.nih.gov
The role of the nucleolus in human genome organization in normal and disease statesNIHNational Cancer Institute2021 to 2024$2,619,610September 21, 2020August 31, 2025KAUFMAN, PAUL D.reporter.nih.gov
Synthetic organogenesis: new paradigms in reconstituting human organ development in vitroNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,586,456September 21, 2021August 31, 2026SIMUNOVIC, MIJOreporter.nih.gov
Vascular networks genetically engineered for protein drug deliveryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,552,882August 15, 2015April 30, 2026MELERO-MARTIN, JUAN Mreporter.nih.gov
Joint Program in Molecules, Cells, and OrganismsNIHNational Institute of General Medical Sciences2021 to 2024$2,531,890July 1, 2020June 30, 2025D'SOUZA, VICTORIA MANUELreporter.nih.gov
Improving transfusion therapy for patients with sickle cell disease with pluripotent stem cell-derived red cellsNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,528,360September 15, 2016May 31, 2025CHOU, STELLA Treporter.nih.gov
Modeling, pathogenesis and treatment of idiopathic pulmonary fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,527,128September 20, 2016May 31, 2025SNOECK, HANS-WILLEM Ereporter.nih.gov
The Genetic Architecture of Human Facial MorphologyNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,521,882July 14, 2017February 28, 2026WEINBERG, SETH Mreporter.nih.gov
Neuronal activity-responsive DNA repair mechanisms and cognitive agingNIHNational Institute on Aging2024$2,516,316September 1, 2024August 31, 2027GREENBERG, MICHAEL ELDONreporter.nih.gov
Molecular and Cellular Dissection of the Pathogenesis of Herpes Simplex Encephalitis with iPSC-Derived CNS and PNS CellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,509,626September 20, 2010March 31, 2025CASANOVA, JEAN-LAURENTreporter.nih.gov
Fine-scale Spatiotemporal Mapping of Cellular Regulatory Networks Directing Heart DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,499,248August 1, 2020July 31, 2025CHI, NEIL Creporter.nih.gov
Characterizing Emerging Humanized Immune Mouse Models for the study of transplant rejection and infectious disease pathology (Epstein Barr Virus)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,464,113February 2, 2021August 30, 2024BROWN, MATTHEW Ereporter.nih.gov
Integrative Modeling of HIV-Associated Neurocognitive Disorder in Human Brain OrganoidsNIHNational Institute on Drug Abuse2021 to 2024$2,456,170August 1, 2020May 31, 2025NOVITCH, BENNETT Greporter.nih.gov
Humanized Mouse Avatars for T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,439,759September 25, 2014May 31, 2024GREINER, DALE LESLIEreporter.nih.gov
A Gata456 Pipeline of DiscoveryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,169January 10, 2017December 31, 2023EVANS, TODD Rreporter.nih.gov
Stem cells for therapeutics discovery in genetic blood disordersNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,429,809September 23, 2016May 31, 2025DALEY, GEORGE Qreporter.nih.gov
Function of Putative Determinant in HematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,418,427August 1, 1993June 30, 2026BIEKER, JAMES Jreporter.nih.gov
Developing Human Pluripotent Stem Cell Tools for Region-Specific Pain CircuitsNIHNational Institute of Neurological Disorders and Stroke2024$2,370,000September 6, 2024August 31, 2027IYER, NISHAreporter.nih.gov
Molecular Aspects of Cytomegalovirus LatencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,342,650December 1, 1984January 31, 2028HANCOCK, MEAGHAN Hreporter.nih.gov
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systemsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,328,420September 20, 2019May 31, 2024SYKES, MEGANreporter.nih.gov
Transplantation of MHC Homozygous Vascular Progenitors in PrimatesNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,302,970September 20, 2016May 31, 2025SLUKVIN, IGOR I.reporter.nih.gov
Engineering optimization and scaling enables high quality pancreatic islet cryopreservation for banking and transplantNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,294,596September 22, 2021July 31, 2025FINGER, ERIK BRIANreporter.nih.gov
MicroRNA regulation of neural tube closureNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,271,604March 10, 2020February 28, 2025PARCHEM, RONALD Jreporter.nih.gov
Determining the Intrinsic and Environmental Signal Contributing to Early T1D ProgressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,260,661September 15, 2020June 30, 2025CHEN, SHUIBINGreporter.nih.gov
Mechanisms of oxysterol-induced oligodendrogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,255,433December 15, 2019November 30, 2024BENNER, ERIC Jreporter.nih.gov
Loss of TDP-43 disrupts the prefrontal neural activity and circuitry: relevance for TDP-43 linked ADRDNIHNational Institute of Neurological Disorders and Stroke2022$2,255,378September 19, 2022August 31, 2025LI, YUNreporter.nih.gov
Functional Validation of TDP-43 splicing repression for frontotemporal degenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,237,856September 1, 2021August 31, 2023WONG, PHILIP Creporter.nih.gov
Alternative RNA splicing events contribute to the onset of islet dysfunction in T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,191,256September 15, 2020June 30, 2024SUSSEL, LORIreporter.nih.gov
Genetic mechanisms of type 1 diabetes risk in stress-induced pancreatic isletsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$2,181,407August 1, 2019May 31, 2023GAULTON, KYLE JEFFRIEreporter.nih.gov
Sox Proteins Modulate Genomic Specificity of B-catenin Regulated Transcription in the Developing GutNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,163,911January 15, 2021December 31, 2025ZORN, AARON Mreporter.nih.gov
Immunogenicity of Human Stem Cell-Derived Beta Cells and Muscle Cells in Humanized MiceNIHOffice of the Director, National Institutes of Health2021 to 2022$2,147,498August 15, 2019July 31, 2024GREINER, DALE LESLIEreporter.nih.gov
UCSD Biomedical Scientist Career Development Program in GlycoscienceNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,105,436July 1, 2018June 30, 2024ESKO, JEFFREY Dreporter.nih.gov
The role of Myt1l in the developing and adult mouse brainNIHNational Institute of Mental Health2021 to 2023$2,094,570April 1, 2019January 31, 2024WERNIG, MARIUSreporter.nih.gov
Extending the temporal and spatial capabilities of single-molecule methodsNIHNational Institute of General Medical Sciences2021 to 2024$2,093,498September 1, 2021August 31, 2025CHU, STEVENreporter.nih.gov
The cis-regulatory grammar and epigenetic control of human interneuron progenitor specificationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,079,315June 15, 2021May 31, 2026KROLL, KRISTEN Lreporter.nih.gov
Embryonic vascular stem-progenitors for treatment of ischemic retinopathiesNIHNational Eye Institute2021 to 2024$2,033,849February 1, 2021January 31, 2026ZAMBIDIS, ELIAS T.reporter.nih.gov
Functional analysis of mammalian midbody RNA in post-mitotic signaling functionsNIHNational Institute of General Medical Sciences2021 to 2024$2,023,221September 16, 2021August 31, 2025SKOP, AHNA RENEEreporter.nih.gov
Skeletal FGF23 production mediated by GPCR/Gq/PKC signalingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,006,965April 1, 2020March 31, 2026BASTEPE, MURATreporter.nih.gov
A Catalog of Cell Types and Genomic Elements in Tissues, Organoids and DiseaseNIHNational Human Genome Research Institute2021$2,002,687February 1, 2017January 31, 2022BERNSTEIN, BRADLEY EVANreporter.nih.gov
Cell adhesion-dependent mechanisms of beta cell growth and homeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,998,151April 1, 2020February 28, 2025CIRULLI, VINCENZINOreporter.nih.gov
A renewable and genetically tractable human stem cell-derived multicellular platform for the study of fibrotic liver diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,974,527March 1, 2021February 28, 2025RICE, CHARLES Mreporter.nih.gov
Pluripotent Stem Cell Derived 3D Retinas for Studies of Early Onset Retinal DegenerationNIHNational Eye Institute2021 to 2024$1,950,685April 1, 2020March 31, 2026WAHLIN, KARL Jreporter.nih.gov
Comprehensive Mapping of Long-Range Chromatin Interactions in Humanand Mouse GenomesNIHNational Human Genome Research Institute2021$1,949,357February 1, 2017January 31, 2023LEE, CHARLESreporter.nih.gov
Regulatory elements of replication timing and 3D genome organizationNIHNational Institute of General Medical Sciences2021 to 2024$1,941,046July 1, 2020June 30, 2025RIVERA-MULIA, JUAN CARLOSreporter.nih.gov
Construction of the integrated human cortical organoids to investigate neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2023$1,916,931September 9, 2019July 31, 2025PARK, IN-HYUNreporter.nih.gov
Molecular definition of pseudohypoparathyroidismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,901,832May 1, 1993June 30, 2025JUEPPNER, HARALD W.reporter.nih.gov
Determining lineage decisions and gene regulatory networks governing the generation of key progenitor cell types during early human brain developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,890,725April 7, 2020March 31, 2025RAMANATHAN, SHARADreporter.nih.gov
Mapping enhancer-gene regulation in single cells to connect genetic variants to target genes and cell typesNIHNational Human Genome Research Institute2021 to 2024$1,861,322September 1, 2020June 30, 2025ENGREITZ, JESSE Mreporter.nih.gov
Multi-omics functional analysis of non-coding regulatory genome for genomic medicineNIHNational Human Genome Research Institute2021 to 2024$1,855,388September 1, 2020June 30, 2025DIAO, YARUIreporter.nih.gov
Metabolic and Transcriptional Reprogramming of Cardiac MaturationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,853,015April 1, 2021March 31, 2025MURRY, CHARLES Ereporter.nih.gov
Exploring Wnt-Fzd signaling specificitiesNIHNational Institute of General Medical Sciences2021 to 2024$1,850,888January 1, 2020December 31, 2024WILLERT, KARL Hreporter.nih.gov
Identifying the role of notch3 in brain pericyte function in health and Alzheimer's diseaseNIHNational Institute of Neurological Disorders and Stroke2023$1,838,781April 15, 2023March 31, 2026SHUSTA, ERIC Vreporter.nih.gov
Neurogenic Inflammatory Response to RSVNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,831,459July 1, 1999June 30, 2025PIEDIMONTE, GIOVANNIreporter.nih.gov
Regenerating Vascularized and Innervated Skeletal Muscle to Treat VML DefectsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,819,089August 5, 2020June 30, 2025GRAYSON, WARREN Lreporter.nih.gov
Molecular dissection of synaptic dysfunction in mental disordersNIHNational Institute of Mental Health2021 to 2024$1,815,127April 1, 2020January 31, 2026PAK, CHANGHUIreporter.nih.gov
Regulation of PINK1 and PARKIN-Dependent MitophagyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,796,738September 25, 2013April 30, 2026HARPER, JEFFREY Wreporter.nih.gov
In search of an HBV cure: novel model systems and targetsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,782,852June 10, 2019May 31, 2024RICE, CHARLES Mreporter.nih.gov
Mechanism and regulation of Hu family RNA binding proteins during neural alternative polyadenylationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,774,737January 15, 2014December 31, 2024LAI, ERIC Creporter.nih.gov
Acoustic Tweezing Cytometry for Efficient Neural DifferentiationNIHNational Institute of General Medical Sciences2021 to 2024$1,764,828September 22, 2021July 31, 2025FU, JIANPINGreporter.nih.gov
Mechanisms of Cell-Based Heart RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,742,404April 1, 2019March 31, 2025SNIADECKI, NATHAN JOHNreporter.nih.gov
Monitoring graft responses to the transplant niche in allogeneic cell replacement therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$1,740,000September 6, 2021August 30, 2025DIGOVICH, CATHERINEreporter.nih.gov
DNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$1,734,519August 1, 2020April 30, 2026JIANG, ZONGLIANGreporter.nih.gov
Molecular underpinnings of Prader-Willi syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,733,926September 9, 2019June 30, 2025CARMICHAEL, GORDON Greporter.nih.gov
Functional analysis of autism risk genes during neural development using single cell seqNIHNational Institute of Mental Health2021 to 2023$1,710,471March 15, 2019January 31, 2025GIRALDEZ, ANTONIO Jreporter.nih.gov
The impact of G-quadruplexes on genome evolutionNIHNational Institute of General Medical Sciences2021 to 2023$1,703,804January 1, 2021December 31, 2024MAKOVA, KATERYNAreporter.nih.gov
Embryonic natural killer cell development and functionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,702,824May 1, 2021April 30, 2025STURGEON, CHRISTOPHER MICHAELreporter.nih.gov
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,700,334September 1, 2024August 31, 2029GOODRUM, FELICIA Dreporter.nih.gov
Bioengineering a chimeric human lungNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,684,888August 7, 2013June 30, 2024VUNJAK-NOVAKOVIC, GORDANAreporter.nih.gov
Modeling and mechanistic investigation of a novel dry AMD mouse model with CLIC4 deleted in RPENIHNational Eye Institute2021 to 2024$1,682,288September 1, 2021May 31, 2026SUNG, CHING-HWAreporter.nih.gov
Plastic States Associated with Cellular Stress and Malignancy: Insights for Prevention and Treatment of Lethal Metaplastic CancersNIHNational Cancer Institute2021 to 2022$1,667,061January 19, 2016December 31, 2023TLSTY, THEA Dreporter.nih.gov
MicroRNA regulation of neural crest differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,661,787August 1, 2019May 31, 2025PARCHEM, RONALD Jreporter.nih.gov
Recombineering-based no-cleavage gene-editing toolkit for large-scale genome engineering and functional screeningNIHNational Institute of General Medical Sciences2021 to 2024$1,645,168August 10, 2021April 30, 2025CONG, LEreporter.nih.gov
Control of cardiomyocyte cell cycle by REST in heart failure and regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,630,521July 15, 2020September 30, 2023ZHOU, BINreporter.nih.gov
Modeling Retinoblastoma Initiation Using 3D-Retinal OrganoidsNIHNational Cancer Institute2021 to 2024$1,605,471May 15, 2020April 30, 2026DYER, MICHAEL Areporter.nih.gov
Elucidating the cis-regulatory grammar of human photoreceptorsNIHNational Eye Institute2021 to 2023$1,594,144April 1, 2020March 31, 2025CORBO, JOSEPHreporter.nih.gov
Phosphoinositide signaling in glaucoma: rescue strategies for Lowe syndromeNIHNational Eye Institute2021 to 2024$1,593,733June 1, 2021May 31, 2025SUN, YANGreporter.nih.gov
High throughput CRISPR-mediated functional validation of regulatory elementsNIHNational Human Genome Research Institute2021$1,571,946February 1, 2021July 31, 2022SHEN, YINreporter.nih.gov
Cone subtype specification in human retinas and organoidsNIHNational Eye Institute2021 to 2023$1,566,838January 1, 2020December 31, 2024JOHNSTON, ROBERT JOHNreporter.nih.gov
Divergent Roles for Hypoxia-Inducible Factor-1 and -2 in Ischemic Retinal DiseaseNIHNational Eye Institute2021 to 2023$1,559,136March 1, 2019February 28, 2025SODHI, AKRIT SINGHreporter.nih.gov
HNF1A in human endocrine cell development and functionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,556,784July 20, 2020June 30, 2025GADUE, PAUL Jreporter.nih.gov
Graduate Training in Cellular and Molecular Pathogenesis of Human DiseasesNIHNational Institute of General Medical Sciences2021 to 2025$1,549,623July 1, 2020June 30, 2030FABRY, ZSUZSANNAreporter.nih.gov
Defining the Human Articular Chondrocyte LineageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,537,754April 1, 2019February 28, 2025CRAFT, APRIL MARIEreporter.nih.gov
Mechanisms of Posterior Heart Field DevelopmentNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,535,814August 1, 2020July 31, 2024CHI, NEIL Creporter.nih.gov
Molecular and functional dissection of the zebrafish hematopoietic stem cell nicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,534,439May 8, 2006November 30, 2024TRAVER, DAVIDreporter.nih.gov
Mechanism of apicosome-driven lumen formation during human and mouse embryogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,525,138September 1, 2020June 30, 2025TANIGUCHI, KENICHIROreporter.nih.gov
Molecular Basis of Human Visual System DisordersNIHNational Eye Institute2021 to 2024$1,521,986June 1, 2012May 31, 2025CHEN, RUIreporter.nih.gov
Network Medicine for Alzheimers Disease: Functional Dissection and Pharmacologic Perturbation of a Human Brain Synaptic Regulatory Expression SignatureNIHNational Institute on Aging2022$1,509,105August 15, 2022July 31, 2025SHULMAN, JOSHUA Mreporter.nih.gov
One-compound, one-islet: A high-throughput platform for small-molecule discoveryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,507,666September 20, 2019July 31, 2023WAGNER, BRIDGET Kreporter.nih.gov
RNA Processing Machines in Biology and DiseaseNIHNational Institute of General Medical Sciences2021 to 2023$1,500,462April 1, 2017August 31, 2023MOAZED, DANESHreporter.nih.gov
A RIPK2-Targeting Apoptosis-Inducing Small Molecule for the Treatment of GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,492,646June 1, 2019March 31, 2024LAIRSON, LUKE LEEreporter.nih.gov
Uncover the role of glia-neuron crosstalk in hereditary spastic paraplegiasNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,491,787June 1, 2020May 31, 2026LI, XUE-JUNreporter.nih.gov
Mimicking, Exploiting, and Understanding Biology's Heterogeneity in 4DNIHNational Institute of General Medical Sciences2021 to 2024$1,486,420September 15, 2020August 31, 2025DEFOREST, COLE Areporter.nih.gov
Gene Expression Signature Based Screening in Ewing SarcomaNIHNational Cancer Institute2021 to 2024$1,484,581February 1, 2023January 31, 2026GORDON, DAVID Jreporter.nih.gov
Improving the Safety of Genome Editing With Human Kidney OrganoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,476,969September 16, 2019May 31, 2024FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Modular Platform for Combinatorial Epigenome ManipulationNIHNational Human Genome Research Institute2021 to 2022$1,469,440January 1, 2018December 31, 2023ADAMS, MARK Dreporter.nih.gov
Transcriptional Factor SOX2, LncRNA HBL1, microRNA1 and PRC2 Epigenetic Complex Compose a Network to Orchestrate Cardiac Differentiation from Human Pluripotent Stem CellsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,465,719July 1, 2019June 30, 2025YANG, LEIreporter.nih.gov
Novel pro-healing scaffolds for cell therapiesNIHNational Institute of General Medical Sciences2021 to 2023$1,460,064May 1, 2020February 28, 2025CRISA, LAURAreporter.nih.gov
Epigenetic regulation of transcriptional programmingNIHNational Institute of General Medical Sciences2021 to 2022$1,435,204May 1, 2018April 30, 2024KURODA, MITZI Ireporter.nih.gov
Altered inflammatory response associated with acquired DNMT3A mutationsNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,432,778May 1, 2021September 30, 2022BYUN, MINJIreporter.nih.gov
Vascularized kidney organoids on chip for efficacy and toxicity testing of somatic genome editingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,427,720September 10, 2019June 30, 2025MORIZANE, RYUJIreporter.nih.gov
Micropattern differentiation and morphogenesis of the human ectodermNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,424,973August 24, 2020July 31, 2025BRIVANLOU, ALI Hreporter.nih.gov
A marker-free technology for mapping the epigenome of cell types in mammalian tissuesNIHNational Human Genome Research Institute2021 to 2024$1,418,857February 4, 2020January 31, 2025DEY, SIDDHARTH SUBHASreporter.nih.gov
An Integrative Computational Framework for DNA Hydroxymethylation Data Mining and InterpretationNIHNational Institute of General Medical Sciences2021 to 2023$1,417,500August 1, 2019July 31, 2024LI, SHENGreporter.nih.gov
Role of exosomes in the coordinated migration of neural crest cells and placodes and ethanol-induced teratogenesisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$1,407,469August 1, 2020July 31, 2025CHEN, SHAO-YUreporter.nih.gov
Mechanisms of mTOR-independent axon growth and guidance defects in TSC2 mutant human neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,400,852May 1, 2020April 30, 2026GOMEZ, TIMOTHY Mreporter.nih.gov
Gene regulation for stem cell differentiationNIHNational Institute of General Medical Sciences2021 to 2023$1,392,584September 1, 2019May 31, 2025PENG, JAMY C.reporter.nih.gov
Human pluripotent stem cells for the study of gastrointestinal dysmotilityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,380,385April 15, 2020March 31, 2025FATTAHI, FARANAKreporter.nih.gov
Developing a microfluidic human neurovascular unit system to investigate genetic and age-related risk factors in Alzheimer's diseaseNIHNational Institute on Aging2022 to 2024$1,372,731September 30, 2022August 31, 2025SPROUL, ANDREW ALEXANDERreporter.nih.gov
Evolution of new regulatory networks via genetic arms races between KRAB zinc finger proteins and retrotransposonsNIHNational Human Genome Research Institute2021 to 2022$1,370,764February 12, 2019January 31, 2025SALAMA, SOFIE REDAreporter.nih.gov
Protein Homeostasis and Proteotoxicity MechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,365,060February 1, 2015May 31, 2026LIN, JONATHANreporter.nih.gov
Quantitative and function analysis platform for repetitive genes and gene isoforms in pluripotency regulation and differentiationsNIHNational Human Genome Research Institute2023 to 2024$1,357,993May 1, 2023April 30, 2026AU, KIN FAIreporter.nih.gov
Angiogenic hydrogel composites for microvascular integration of organoid graftsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,355,710May 1, 2021January 31, 2026BAKER, BRENDON Mreporter.nih.gov
Organization of the Mammalian Mitotic SpindleNIHNational Institute of General Medical Sciences2021 to 2022$1,352,508August 1, 1996February 29, 2024COMPTON, DUANE A.reporter.nih.gov
Illuminating the Molecular Logic of Mammalian Synaptic Circuit AssemblyNIHNational Institute of Mental Health2024$1,349,865September 4, 2024September 3, 2027SANDO, RICHARD CHESLOCKreporter.nih.gov
Causes and Consequences of Aneuploidy in HeSCsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,346,597May 12, 2020March 31, 2026GODEK, KRISTINA Mreporter.nih.gov
Genetic Diagnosis of Neurodevelopmental Disorders in IndiaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,342,303September 10, 2018February 28, 2025BIELAS, STEPHANIE LEEreporter.nih.gov
Cell Interactions in Development of the Mammalian KidneyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,339,902September 1, 1998December 31, 2023MCMAHON, ANDREW P.reporter.nih.gov
Host DNA repair pathways in human cytomegalovirus replicationNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,336,101June 16, 2023May 31, 2028GOODRUM, FELICIA Dreporter.nih.gov
Cell-type– and developmental stage–specific regulation of gene expression in the retinaNIHNational Eye Institute2021 to 2023$1,319,324February 1, 2020January 31, 2025DYER, MICHAEL Areporter.nih.gov
Cellular and Molecular Basis of Human Primordial Germ Cell SpecificationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,311,481December 20, 2014April 30, 2026CLARK, AMANDERreporter.nih.gov
Enabling Precision Genomics Using Adaptive VariationNIHNational Institute of General Medical Sciences2021 to 2023$1,305,272August 1, 2020April 30, 2025NIELSEN, RASMUSreporter.nih.gov
A Translational Bioinformatics Approach to Rescuing Synaptic and Neurophysiologic Dysfunction in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$1,305,180September 15, 2018May 31, 2025TEICH, ANDREW FRANKLINreporter.nih.gov
PTPN2 mutations affect islet beta cell susceptibility in T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,290,590July 1, 2020April 30, 2025SUSSEL, LORIreporter.nih.gov
3D Printed Scaffolds for Primate Spinal Cord Injury RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,290,219January 1, 2020December 31, 2023TUSZYNSKI, MARK H.reporter.nih.gov
Decode the Impact of SARS-CoV-2 on Human PancreasNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,285,210July 5, 2021June 30, 2024CHEN, SHUIBINGreporter.nih.gov
Epigenetic control of the human X chromosomeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,282,146May 1, 2019April 30, 2024PLATH, KATHRINreporter.nih.gov
Genetic and Molecular Analyses of Human LINE-1 RetrotranspositionNIHNational Institute of General Medical Sciences2021 to 2024$1,276,667September 30, 1999March 31, 2025MORAN, JOHN V.reporter.nih.gov
Developmental Regulation of Gene Expression by Long Undecoded Transcript IsoformsNIHNational Institute of General Medical Sciences2021 to 2024$1,275,707January 1, 2021December 31, 2024UNAL, ELCINreporter.nih.gov
Intestinal Niche in Homeostasis and Epithelial RegenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,268,720September 5, 2014August 31, 2025ESTES, MARY KOLBreporter.nih.gov
Mesodermal Commitment of the Definitive Hematopoietic ProgramNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,268,334January 15, 2021April 30, 2025STURGEON, CHRISTOPHER MICHAELreporter.nih.gov
Metallothionein 1E as a Central Regulator of Human Pancreatic Beta Cell Function and SurvivalNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,242,082July 1, 2019May 31, 2023CHEN, SHUIBINGreporter.nih.gov
Single Cell Profiling To Define Biomarkers Of Photoreceptor Dysfunction After Gene Editing Within PSC-Derived OrganoidsNIHNational Eye Institute2021 to 2022$1,223,974September 5, 2018June 30, 2024SAHA, KRISHANUreporter.nih.gov
Defining the intestinal stem cell niche during organoid development into a functional human intestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,222,000September 1, 2014August 31, 2024HELMRATH, MICHAEL A.reporter.nih.gov
Epigenomic profiling of complex tissues with single-cell CUT&RUNNIHNational Human Genome Research Institute2022 to 2023$1,217,769April 19, 2019February 29, 2024HENIKOFF, STEVENreporter.nih.gov
In vivo development and reactivity of human autoreactive T cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,215,000November 15, 2018October 31, 2024CREUSOT, REMI Jreporter.nih.gov
Deciphering Genetic and Epigenetic Regulatory Logic of Germ Layer Differentiation with Manifold LearningNIHNational Institute of General Medical Sciences2021 to 2023$1,214,822August 1, 2019April 30, 2025KRISHNASWAMY, SMITAreporter.nih.gov
Niche support of human intestinal stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,213,203September 1, 2014August 31, 2024SPENCE, JASONreporter.nih.gov
A novel progenitor population in pancreatic endocrine cell developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,211,250April 1, 2019March 31, 2025SNEDDON, JULIE BETHreporter.nih.gov
Linking human islet structural heterogeneity to beta cell stateNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,211,250September 20, 2022June 30, 2025SNEDDON, JULIE BETHreporter.nih.gov
Functional Dissection of New Retinal CircuitsNIHNational Eye Institute2021 to 2022$1,209,256February 1, 2019January 31, 2024ZHOU, Z JIMMYreporter.nih.gov
Uncovering the Genetic Mechanisms Behind Joint-Specific OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,202,184April 1, 2018January 31, 2024CAPELLINI, TERENCE Dreporter.nih.gov
Quantitative and function analysis platform for repetitive genes and gene isoforms in pluripotency regulation and differentiationsNIHNational Human Genome Research Institute2021 to 2022$1,200,000July 15, 2021January 31, 2023AU, KIN FAIreporter.nih.gov
SLC9A3 regulation of esophageal dilated intercellular spaces in EoE SubtypesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,187,668April 22, 2019March 31, 2023HOGAN, SIMON PATRICKreporter.nih.gov
GENETICS OF EARLY ONSET RETINAL DISEASESNIHNational Eye Institute2021 to 2023$1,187,060December 1, 2007July 31, 2026CHEN, RUIreporter.nih.gov
Transcriptional and Epigenetic Control of Pluripotency and Self-Renewal by Honey Bee Royalactin and its human structural analogNIHNational Institute of General Medical Sciences2021 to 2023$1,186,613August 15, 2020January 18, 2024WANG, KEVIN CHUN-KAIreporter.nih.gov
Human Brain Cancer, Rather than Brain Cancer Cells, on a PlateNIHNational Cancer Institute2021$1,186,500September 20, 2017August 31, 2022FINE, HOWARD A.reporter.nih.gov
PROGRAM MANAGEMENT AND NHLBI SR AND SPA SOLUTION TASK ORDER 11NIHNational Heart, Lung, and Blood Institute2023$1,180,356February 17, 2023August 16, 2023reporter.nih.gov
UG Support Administrative Supplement: Computational Models of the Human Cell Cycle to Reveal Disease Mechanism and Inform TreatmentNIHNational Institute of General Medical Sciences2021 to 2023$1,176,505September 11, 2020July 31, 2024PURVIS, JEREMYreporter.nih.gov
Function, composition, and mechanism of RNA splicing factories in cardiomyopathyNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,160,684December 10, 2022August 9, 2024MURRY, CHARLES Ereporter.nih.gov
The Diversity Outbred Diabetes ProjectNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,146,901April 1, 2014March 31, 2023ATTIE, ALAN Dreporter.nih.gov
SPOTs: Optical Technologies for Instantly Quantifying Multicellular Response ProfilesNIHNational Institute of General Medical Sciences2021 to 2023$1,137,513June 1, 2020March 31, 2025CHIOU, PEI-YUreporter.nih.gov
Lung epithelial cell specification in human pluripotent stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,135,872April 1, 2019March 31, 2023SNOECK, HANS-WILLEM Ereporter.nih.gov
SPP1, Oxidative Stress, and Lead ToxicityNIHNational Institute of Environmental Health Sciences2021 to 2022$1,132,499September 30, 2018August 31, 2024LU, QUANreporter.nih.gov
Role of the gut microbiome in pesticide-induced effects on child neurodevelopmentNIHNational Institute of Environmental Health Sciences2021 to 2024$1,131,300February 17, 2020December 31, 2025MAO, JIAN-HUAreporter.nih.gov
Scaffolds for culture and transplantation of islet organoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,101,378July 1, 2020March 31, 2024SHEA, LONNIE Dreporter.nih.gov
Identity, mechanisms and early life impacts of transporter interfering compoundsNIHNational Institute of Environmental Health Sciences2021 to 2022$1,098,042June 1, 2018May 31, 2024HAMDOUN, AMRO Mreporter.nih.gov
The Role of RNA Modifications in Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,086,750April 20, 2019June 30, 2024HOLLEY, CHRISTOPHER LEEreporter.nih.gov
Hereditary Cancer Variants of Uncertain Significance in Stem CellsNIHNational Cancer Institute2021 to 2024$1,085,466April 4, 2019March 31, 2026HEINEN, CHRISTOPHER D.reporter.nih.gov
Toxic Effects of Anesthetics in Developing White MatterNIHNational Institute of General Medical Sciences2021 to 2023$1,080,750April 1, 2020March 31, 2025MINTZ, CYRUS DAVIDreporter.nih.gov
Mechanisms of Hedgehog Regulation of Intestinal Villus MorphogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,053,000March 1, 2019February 28, 2025WALTON, KATHERINE DEMPSEYreporter.nih.gov
Transcriptional Determinants of the Fate Trajectories of Single Human Glial Progenitor Cells in Response to Demyelination in VivoNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,051,297April 1, 2019January 31, 2025GOLDMAN, STEVEN ALANreporter.nih.gov
Endothelial Cell Cycle State and Cell FateNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,047,289August 15, 2019June 30, 2024HIRSCHI, KAREN KEMPERreporter.nih.gov
Characterizing the Conformations and Neurotoxic Species of HuntingtinNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,027,183July 15, 2021June 30, 2023KHOSHNAN, ALIreporter.nih.gov
Unraveling mechanisms of genome regulation to understand and improve human healthNIHNational Institute of General Medical Sciences2021 to 2023$1,023,089September 9, 2016June 30, 2024COTNEY, JUSTIN LEEreporter.nih.gov
Understanding epigenetic remodeling in primordial germ cellsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,022,943February 5, 2009April 30, 2025CLARK, AMANDERreporter.nih.gov
Towards Novel Differentiation Therapies for Neuroblastoma.NIHNational Cancer Institute2021 to 2024$1,022,242May 1, 2019April 30, 2025BARBIERI, EVELINEreporter.nih.gov
Identifying therapeutic strategies for the multisystem genetic disorder Pseudoxanthoma ElasticumNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,015,872February 1, 2020November 30, 2024DEB, ARJUNreporter.nih.gov
Training Program in Developmental and Stem Cell BiologyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,014,534September 18, 2010April 30, 2026STUHLMANN, HEIDIreporter.nih.gov
Kidney Microphysiological Analysis Platforms (MAP) to Optimize Function and Model DiseaseNIHNational Center for Advancing Translational Sciences2021$1,006,126July 25, 2017June 30, 2024BONVENTRE, JOSEPH VINCENTreporter.nih.gov
Reversing Cellular immortality in cancerNIHNational Cancer Institute2021$972,125September 8, 2015August 31, 2024ARTANDI, STEVEN Ereporter.nih.gov
Determining the role of CLN3 in the eyeNIHNational Eye Institute2021 to 2022$949,115April 1, 2019January 31, 2025SINGH, RUCHIRAreporter.nih.gov
Studies of the initiation and progression of small cell lung cancer using cells derived by differentiation from human pluripotent stem cellsNIHNational Cancer Institute2021 to 2022$923,274February 9, 2018January 31, 2025VARMUS, HAROLD E.reporter.nih.gov
The Role of NMD in Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$921,904July 1, 2018March 31, 2023WILKINSON, MILES FROMEreporter.nih.gov
Mapping human hematopoietic stem cell developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$917,280July 1, 2021April 30, 2025MIKKOLA, HANNA KATRI ANNIKKIreporter.nih.gov
The Role of MDM2 in FMRP regulation of neuronal developmentNIHNational Institute of Mental Health2021 to 2022$917,272July 9, 2018April 30, 2024ZHAO, XINYUreporter.nih.gov
Functional characterization of craniofacial enhancers at single cell and single base pair resolutionNIHNational Institute of Dental & Craniofacial Research2021 to 2023$910,042July 3, 2019June 30, 2024COTNEY, JUSTIN LEEreporter.nih.gov
lntegration and Visualization of Diverse Biological DataNIHNational Institute of General Medical Sciences2021 to 2022$896,588April 1, 2005March 31, 2024TROYANSKAYA, OLGA Greporter.nih.gov
Proopiomelanocortin gene expression and obesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$891,662August 1, 2004March 31, 2024LOW, MALCOLM JAMESreporter.nih.gov
Development and Maintenance of the Human Photoreceptor-Bipolar Cell Synapse.NIHNational Eye Institute2021 to 2024$884,824June 1, 2020May 31, 2025NAGIEL, AARONreporter.nih.gov
AI-guided miniproteins driving the production and functional endurance of pancreatic islet tissue from pluripotent stem cells.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$875,714September 1, 2024August 31, 2025CIRULLI, VINCENZINOreporter.nih.gov
Harnessing Induced Human Intestinal Organoids (iHIOs) and Metagenomics to Unravel Host Immune-microbiota Interactions During Cancer Chemotherapy-associated Clostridium difficile InfectionsNIHNational Cancer Institute2021 to 2024$874,953June 1, 2020May 31, 2025APEWOKIN, SENUreporter.nih.gov
REGULATION OF NICHE CELL DIFFERENTIATION TO SUSTAIN INTESTINAL STEM CELL REGENERATION AGAINST GUT INFLAMMATIONNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$870,194January 1, 2020December 31, 2024HAN, XIAONANreporter.nih.gov
Engineering human islet-like organoids for transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$865,040September 30, 2018May 31, 2022EVANS, RONALD Mreporter.nih.gov
Experimental and bioinformatics platform for epigenome analysis using nanopore sequencingNIHNational Institute of General Medical Sciences2021 to 2023$864,924September 27, 2021July 2, 2023AU, KIN FAIreporter.nih.gov
Gene Therapy for Hearing and Balance DisordersNIHNational Institute on Deafness and Other Communication Disorders2021 to 2022$846,072August 1, 2018July 31, 2023COREY, DAVID Preporter.nih.gov
Epigenomic profiling of complex tissues with single-cell CUT&RUNNIHNational Human Genome Research Institute2021 to 2022$845,319April 19, 2019March 31, 2022HENIKOFF, STEVENreporter.nih.gov
Experimental and bioinformatics platform for epigenome analysis using nanopore sequencingNIHNational Institute of General Medical Sciences2023 to 2024$842,968September 27, 2021June 30, 2025AU, KIN FAIreporter.nih.gov
Regulation of microtubule organizing centers during mammalian gametogenesisNIHNational Institute of General Medical Sciences2021 to 2022$839,024January 1, 2016May 20, 2022JORDAN, PHILIP Wreporter.nih.gov
Generation of mature human embryonic stem cell-derived left ventricular cardiomyocytes for transplantation in a large animal modelNIHNational Heart, Lung, and Blood Institute2021 to 2022$835,309July 15, 2019January 16, 2023ARDEHALI, REZAreporter.nih.gov
From Variants to Mechanisms for Cardiac ArrhythmiasNIHNational Heart, Lung, and Blood Institute2023$825,573August 1, 2023June 30, 2028TUCKER, NATHAN Rreporter.nih.gov
Defining the Self-Renewal Program in Human Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$823,930September 20, 2014June 30, 2024MIKKOLA, HANNA KATRI ANNIKKIreporter.nih.gov
Microenvironmental cues control pancreas cell fate and beta-cell maturationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$816,416September 15, 2018July 31, 2024SHIH, HUNG-PINGreporter.nih.gov
Biorepository of iPSC lines from diverse rat strains for regenerative medicine researchNIHOffice of the Director, National Institutes of Health2021$801,204September 2, 2018May 31, 2023KIM, KWANG-SOOreporter.nih.gov
Visualization, modeling and validation of chromatin interaction dataNIHNational Human Genome Research Institute2021 to 2022$790,000July 1, 2019September 30, 2024YUE, FENGreporter.nih.gov
The Cardiac Role of Filamin CNIHNational Heart, Lung, and Blood Institute2021 to 2022$790,000January 1, 2019December 31, 2022CHEN, JUreporter.nih.gov
Control of endocrine pancreatic beta-cell fate, function, and proliferationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$785,000April 1, 2018February 29, 2024WRIGHT, CHRISTOPHER Vreporter.nih.gov
Novel humanized mouse model developed from cord blood CD34 positive HSC and autologous iPS cell derived thymusNIHNational Institute of Allergy and Infectious Diseases2021$782,684May 1, 2017April 30, 2022BREHM, MICHAEL ALLENreporter.nih.gov
Role of histone ubiquitination in neurodevelopment and diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$781,274December 15, 2017November 30, 2022BIELAS, STEPHANIE LEEreporter.nih.gov
Metabolic regulation of heart formationNIHNational Heart, Lung, and Blood Institute2021 to 2022$780,000June 1, 2019May 31, 2023NAKANO, ATSUSHIreporter.nih.gov
Nanofibrous self-gelling microspheres for heart regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2022$780,000September 15, 2019August 31, 2024MA, PETER Xreporter.nih.gov
Engineering an Islet Thread from zwitterionically modified alginates for type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$778,391July 1, 2018April 30, 2025MA, MINGLINreporter.nih.gov
Innate Immunity of Zika Virus Infection In Human Neural ProgenitorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$777,770April 16, 2020March 31, 2026STOKES, CALEBreporter.nih.gov
Mechanisms of Cell Polarity EstablishmentNIHNational Institute of General Medical Sciences2021 to 2022$769,608April 1, 2004July 31, 2024MACARA, IAN Greporter.nih.gov
Cellular and molecular mechanisms disrupted in 22q13 deletion syndrome and autismNIHNational Institute of Mental Health2021 to 2022$762,500April 1, 2018December 31, 2023SHCHEGLOVITOV, OLEKSANDRreporter.nih.gov
DNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$761,382August 1, 2020September 30, 2022JIANG, ZONGLIANGreporter.nih.gov
Using formins to build distinct structures in cardiomyocytesNIHNational Heart, Lung, and Blood Institute2021 to 2022$761,086September 1, 2019August 31, 2024QUINLAN, MARGOT Ereporter.nih.gov
Transplantation of human stem cell-derived neurons for retinal ganglion cell replacement and optic nerve regeneration.NIHNational Eye Institute2021 to 2024$756,812September 30, 2020August 31, 2025JOHNSON, THOMAS VINCENTreporter.nih.gov
The development and application of tools to characterize the level and function of RNA polymerase III transcription dynamics during cellular differentiationNIHNational Human Genome Research Institute2022 to 2024$747,000November 24, 2021October 31, 2024VAN BORTLE, KEVINreporter.nih.gov
The role of autism susceptibility genes in the 16p11.2 locus on the development and function of human stem cell-derived neural cellsNIHNational Institute of Mental Health2022 to 2024$746,998January 27, 2022November 30, 2024WELLS, MICHAEL FREDERICKreporter.nih.gov
Understanding Brain Development Through the Lens of MetabolismNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$738,142June 1, 2019March 31, 2024BHADURI, APARNAreporter.nih.gov
Development of Optic Nerve Relays to Restore Retinofugal ConnectionsNIHNational Eye Institute2021 to 2023$736,206September 1, 2021August 31, 2024DO, JIUN LAPreporter.nih.gov
Developing Remyelination Strategies for Demyelinating Optic Neuropathies Using Human Pluripotent Stem CellsNIHNational Eye Institute2022 to 2024$730,625January 1, 2022December 31, 2024CHAMLING, XITIZreporter.nih.gov
Training Program in Cellular and Molecular Biology and GeneticsNIHNational Institute of General Medical Sciences2021$728,886July 1, 1987June 30, 2023QUERY, CHARLES Creporter.nih.gov
Mechanisms regulating the early stages of UV-induced skin cancerNIHNational Institute of Environmental Health Sciences2021 to 2022$724,500April 1, 2018March 31, 2024SEYKORA, JOHN T.reporter.nih.gov
Improving Brain Organoid Models by Mediating Metabolic DysregulationNIHNational Institute of Mental Health2022 to 2024$722,100January 18, 2022December 31, 2025ANDREWS, MADELINEreporter.nih.gov
Molecular control of pluripotency in humansNIHNational Institute of General Medical Sciences2021 to 2022$713,182May 1, 2014August 31, 2024IVANOVA, NATALIA Breporter.nih.gov
A Human Organoid Model of Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$706,000September 15, 2018June 30, 2023FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Application of a novel dCasNano-based Epigenetic Editing to Treat Rett SyndromeNIHNational Institute of Neurological Disorders and Stroke2024$698,459September 15, 2024February 28, 2026TSAI, YI-TINGreporter.nih.gov
Epigenetic disruptions of PBDEs during neurodevelopmentNIHNational Institute of Environmental Health Sciences2021 to 2022$696,017September 1, 2018May 31, 2024SAHA, RAMENDRA Nreporter.nih.gov
A Thermoreversible 3D Manufacturing Platform for Scalable Production of Dopaminergic Neurons for Parkinson's Disease TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$685,839August 1, 2021January 31, 2024MUCKOM, RIYAreporter.nih.gov
Neural Stem Cell Extracellular Vesicle Treatment for Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$679,411June 1, 2022May 31, 2025STICE, STEVEN Lreporter.nih.gov
Cell-based Platform for Gene Delivery to the BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$677,159March 1, 2018November 30, 2023BATRAKOVA, ELENAreporter.nih.gov
Piezo1 in neural stem cell mechano-regulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$676,398September 30, 2018June 30, 2024PATHAK, MEDHA Mreporter.nih.gov
Role of VZV latency transcript (VLT) and ORF63 in latency and reactivationNIHNational Institute of Allergy and Infectious Diseases2021$666,635November 17, 2020October 31, 2021COHRS, RANDALL J.reporter.nih.gov
Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biologyNIHNational Institute of Neurological Disorders and Stroke2021$662,126May 1, 2020April 1, 2022DISNEY, MATTHEW Dreporter.nih.gov
The Role of the De-condensed Structure of Nascent Chromatin During T Cell DifferentiationNIHNational Institute of Allergy and Infectious Diseases2021$653,648February 3, 2017January 31, 2023MAZO, ALEXANDER Mreporter.nih.gov
Mechanistic Characterization of Calcium-Activated Chloride Channels in Retinal Pigment EpitheliumNIHNational Institute of General Medical Sciences2021 to 2022$648,000May 1, 2018March 31, 2024YANG, TINGTINGreporter.nih.gov
Wnt pathway dynamics and their role in generating self-organized ectodermal patternsNIHNational Institute of General Medical Sciences2021 to 2022$645,549January 1, 2018December 31, 2022WARMFLASH, ARYEHreporter.nih.gov
Modeling Genetic Inner Ear Disorders with Human Pluripotent Stem CellsNIHNational Institute on Deafness and Other Communication Disorders2021$637,479December 4, 2016November 30, 2023HASHINO, ERIreporter.nih.gov
Dissecting the mechanisms behind biphasic beta cell disease caused by mutations in HNF1alphaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$635,930September 30, 2021June 29, 2025LEAVENS, KARLA FITZGERALDreporter.nih.gov
Mechanisms of trophoblast lineage formation: Impact on postimplantation placental developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$630,384August 1, 2018March 31, 2026KNOTT, JASON GLENNreporter.nih.gov
Dysregulation of Histone Acetylation in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$624,231July 11, 2023June 30, 2025SOLDNER, FRANKreporter.nih.gov
Genome wide identification and functional analysis of chromatin regulatory RNAsNIHNational Human Genome Research Institute2021$616,014December 1, 2017November 30, 2022STRAIGHT, AARON Freporter.nih.gov
Repairing the Kidney Endothelium via Targeted Extracellular Matrix ModifiersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$614,000August 1, 2020July 31, 2024WERTHEIM, JASON Areporter.nih.gov
Establishing the role of OCRL as a novel ciliary gene in weight regulation in human and murine modelsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$608,650September 1, 2022April 30, 2025THAKER, VIDHU V.reporter.nih.gov
Characterizing new proteins that determine AP-1 recruitment and distributionNIHNational Institute of General Medical Sciences2021 to 2022$601,984September 1, 2019July 31, 2024DUNCAN, MARA Creporter.nih.gov
Molecular Mechanisms of Diabetic Retinal Ganglion Cell Dysfunction and Neurovascular Crosstalk in Early Diabetic RetinopathyNIHNational Eye Institute2021 to 2023$598,239March 1, 2019February 28, 2025SACHDEVA, MIRA MENONreporter.nih.gov
Transcriptional regulatory networks govering placental development.NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$597,887August 24, 2018May 31, 2024TUTEJA, GEETUreporter.nih.gov
In situ functional genomics to understand transcriptional regulationNIHNational Human Genome Research Institute2022$579,000June 1, 2022May 31, 2023SANJANA, NEVILLEreporter.nih.gov
Role of Mitochondrial Metabolism in Regulating Species-Specific Developmental RatesNIHNational Institute of General Medical Sciences2024$578,254September 1, 2024June 30, 2025DIAZ CUADROS, MARGARETEreporter.nih.gov
Understanding human pancreas development for diabetes cell-replacement therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$570,128July 1, 2012July 31, 2023HUANGFU, DANWEIreporter.nih.gov
Stem Cell-Derived Developmental Human Cortical Interneurons to Treat Intractable EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021$565,775May 1, 2021April 30, 2024CHUNG, SANGMIreporter.nih.gov
Embryonic stem cell therapy after cervical contusion SCI in NHPsNIHNational Institute of Neurological Disorders and Stroke2021$558,167September 25, 2017June 30, 2024BRESNAHAN, JACQUELINE Creporter.nih.gov
Dissecting ocular congenital cranial dysinnervation disorders through whole genome sequence analysisNIHNational Eye Institute2021$557,566April 1, 2017February 28, 2023ENGLE, ELIZABETH C.reporter.nih.gov
Molecular basis of Zika-induced microcephalyNIHNational Institute of Neurological Disorders and Stroke2021$556,972September 30, 2018February 28, 2022GLEESON, JOSEPH Greporter.nih.gov
Assessing Tyrosine Kinase Inhibitors-induced Cardiotoxicity with an Organoid-AI SystemNIHNational Heart, Lung, and Blood Institute2024$547,020September 20, 2024August 31, 2025YANG, HUAXIAOreporter.nih.gov
Engineering Human Myocardium with Hybrid Biomaterials for Heart RegenerationNIHNational Heart, Lung, and Blood Institute2021$542,011February 1, 2017January 31, 2023COULOMBE, KAREEN LKreporter.nih.gov
Tau mislocalization assay to screen AD therapeutics using compartmentalized chipsNIHNational Institute on Aging2022 to 2023$535,000February 1, 2022January 31, 2025TAYLOR, ANNE MARIONreporter.nih.gov
Molecular tools for targeting RNANIHNational Institute of General Medical Sciences2021 to 2022$515,983April 1, 2020October 1, 2022HSU, PATRICKreporter.nih.gov
The DAXX/ATRX/H3.3 axis in ERV regulation and tumor suppressionNIHNational Cancer Institute2022 to 2024$512,578February 1, 2022January 31, 2025WASYLISHEN, AMANDA RIETTAreporter.nih.gov
Leveraging a newly identified EZH1 associated syndrome to explore pharmacological recovery of neurodevelopmental disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$509,144August 17, 2022July 31, 2024AKIZU, NAIARAreporter.nih.gov
Early Epigenetic Footprint of Neurological DiseasesNIHNational Institute of Mental Health2021 to 2022$498,000July 1, 2018June 30, 2023KREIMER, ANATreporter.nih.gov
Investigation of sub-lineages in pulmonary neuroendocrine cells and identification of the cells of origin of small cell lung cancerNIHNational Cancer Institute2021 to 2022$498,000September 16, 2020August 31, 2023CHEN, JOYCE HUANHUANreporter.nih.gov
Molecular Determinants of Hemogenic EndotheliumNIHNational Heart, Lung, and Blood Institute2021$495,137September 1, 2018June 30, 2023SLUKVIN, IGOR I.reporter.nih.gov
Training Program in Basic and Clinical GeneticsNIHNational Institute of General Medical Sciences2021$492,689July 1, 1998June 30, 2023HAMILTON, BRUCE Areporter.nih.gov
Role of the Rett Syndrome-causing gene MeCP2 in 3D chromosomal organization and rescue of cellular disease phenotypesNIHNational Institute of Mental Health2021 to 2022$491,612April 1, 2020January 31, 2023LIU, X. SHAWNreporter.nih.gov
Use of Human Stem Cell-derived RGCs to Study the Mechanism of Optineurin-associated GlaucomaNIHNational Eye Institute2021 to 2022$490,527November 1, 2019January 31, 2024DAS, ARUPRATANreporter.nih.gov
Human cerebral organoids as a model system for neural development and diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$488,040August 1, 2020July 31, 2024WATANABE, MOMOKOreporter.nih.gov
Functional analysis of the immune landscape in IDH mutant gliomasNIHNational Institute of Neurological Disorders and Stroke2021$486,750April 15, 2021September 30, 2023TABAR, VIVIANEreporter.nih.gov
Molecular and cellular pathways driving competency for human vagal neural crest specificationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$486,750September 19, 2023August 31, 2025STUDER, LORENZ P.reporter.nih.gov
Graduate Training in Stem Cell Biology and Regenerative MedicineNIHNational Institute of General Medical Sciences2021$484,649July 1, 2017June 30, 2022WEISSMAN, IRVING L.reporter.nih.gov
Characterization of mechanisms regulating multiciliated cell specification using patient-specific induced pluripotent stem cells.NIHNational Heart, Lung, and Blood Institute2021$483,525March 15, 2018December 31, 2021RYAN, AMY LEANNEreporter.nih.gov
Regulation of beta cell identity and dedifferentiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$473,951May 1, 2015August 31, 2022HEBROK, MATTHIASreporter.nih.gov
Histone chaperones and cell state regulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023$470,931September 1, 2023August 31, 2024WASYLISHEN, AMANDA RIETTAreporter.nih.gov
The Role of YAP1:TEAD Enhancers in the Retinoic Acid-Regulatory Network of Cardiac ProgenitorsNIHNational Heart, Lung, and Blood Institute2022$468,721September 12, 2022August 31, 2024ESTARAS, CONCEPCIONreporter.nih.gov
Molecular Mechanisms of Purkinje Cell Degeneration in Ataxia-TelangiectasiaNIHNational Institute of Neurological Disorders and Stroke2021$466,125April 1, 2021September 30, 2023HATTEN, MARY ELIZABETHreporter.nih.gov
Single gene inborn errors of immunity underlying SARS-CoV-2-related multisystem inflammatory syndrome in children: a new approach to tackle a seemingly old puzzleNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$466,125May 20, 2022April 30, 2024ZHANG, SHEN-YINGreporter.nih.gov
Elucidating the mechanism by which ADAR1 prevents autoimmunity against self RNANIHNational Institute of Allergy and Infectious Diseases2023 to 2024$466,125February 8, 2023January 31, 2025RICE, CHARLES Mreporter.nih.gov
Advancing chemical risk assessment through development, validation and integration of high throughput mechanistic in vitro dataNIHNational Institute of Environmental Health Sciences2022$462,306August 16, 2022July 31, 2025LAM, JULEENreporter.nih.gov
Mapping of Novel Candidate Functional Elements with Bru-Seq TechnologyNIHNational Human Genome Research Institute2021$460,492February 1, 2021January 31, 2022LJUNGMAN, MATSreporter.nih.gov
The Epigenome in Substance Abuse Disorders: Engineering New Tools to Dissect Function from FormNIHNational Institute on Drug Abuse2021$456,000September 1, 2017August 31, 2023KEUNG, ALBERTreporter.nih.gov
Sugar-coating our way to genetically modified mesenchymal stem cells: Glycocalyx-inspired cell culture substrates that prime mesenchymal stem cells for polycation-mediated pDNA delivery.NIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2024$453,925May 10, 2024August 31, 2025KUMAR, RAMYAreporter.nih.gov
Systematic characterization of trans regulation of A-to-I RNA editing in neuronsNIHNational Institute of Mental Health2021$453,815September 15, 2017June 30, 2022LI, JIN BILLYreporter.nih.gov
Contribution of GABA-A receptor subunit deletions to Angelman syndrome pathophysiologyNIHNational Institute of Neurological Disorders and Stroke2021$451,000September 20, 2021February 28, 2025LEVINE, ERIC Sreporter.nih.gov
Visualizing functional retinal integration of transplanted retinal ganglion cellsNIHNational Eye Institute2022 to 2023$450,313September 30, 2022August 31, 2024JOHNSON, THOMAS VINCENTreporter.nih.gov
Human Trophoblast Stem Cells: the In Vivo Niche and Relationship to Pluripotent Stem CellsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$449,657March 15, 2017February 28, 2023PARAST, MANA Mreporter.nih.gov
Developing 3D brain circuits on-a-chip for in vitro study of human cortico-striatal circuitry development and connectivityNIHNational Institute of Mental Health2023 to 2024$447,303July 1, 2023June 30, 2026GUO, ZIYUANreporter.nih.gov
Cell fate determination in the early development of the otic lineage in human inner ear organoidsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$447,125July 5, 2021June 30, 2024TANG, PEI-CIAOreporter.nih.gov
Diurnal Experimental Models to Investigate Neural Mechanisms of Sleep Disturbance in Smith-Magenis SyndromeNIHNational Institute of Neurological Disorders and Stroke2021$443,728September 15, 2021February 29, 2024IWASE, SHIGEKIreporter.nih.gov
Dynamic control of cortical development and disease by mRNA stabilityNIHNational Institute of Neurological Disorders and Stroke2022$442,750June 1, 2022May 31, 2025SILVER, DEBRAreporter.nih.gov
Developing single nuclei tRNA-seq to profile tRNA diversity at the single cell levelNIHNational Institute of Neurological Disorders and Stroke2024$442,750July 15, 2024June 30, 2026SCHAFFER, ASHLEIGH Ereporter.nih.gov
Novel AAV Capsids and Gene Regulatory Elements for GeneExpression in MicrogliaNIHNational Institute of Mental Health2021 to 2022$440,000April 1, 2021March 31, 2024DEVERMAN, BENJAMIN Ereporter.nih.gov
The cellular and molecular signatures of postnatal human RTT astrocytesNIHNational Institute of Mental Health2021 to 2022$438,625April 1, 2021March 31, 2025BALLAS, NURITreporter.nih.gov
BET regulation of mitosis and pluripotency establishmentNIHNational Institute of General Medical Sciences2021 to 2022$438,492August 1, 2018February 28, 2023HU, KEJINreporter.nih.gov
Molecular Basis of SIX2-related Frontonasal DysplasiaNIHNational Institute of Dental & Craniofacial Research2023 to 2024$437,250March 1, 2023February 28, 2026JIANG, RULANGreporter.nih.gov
Fmr1 Function and Repeat Expansion in the Developing GermlineNIHNational Institute of General Medical Sciences2021$435,875December 26, 2017November 30, 2022LAIRD, DIANA Jreporter.nih.gov
Gold nanoparticle Neurosensory Epiretinal Implant to Treat Photoreceptor Vision LossNIHNational Eye Institute2022 to 2023$435,875September 1, 2022August 31, 2025HAJRASOULIHA, AMIR REZAreporter.nih.gov
Evaluating the Potential of Human Induced Pluripotent Stem Cells (hiPSC) For Cartilage RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$435,442July 5, 2017June 30, 2023BHUTANI, NIDHIreporter.nih.gov
Frequent concatemeric insertions during AAV6/Cas9-mediated genome editing: Detection and PreventionNIHOffice of the Director, National Institutes of Health2021 to 2022$434,351June 15, 2021May 31, 2023NAKAUCHI, HIROMITSUreporter.nih.gov
Discovery of aberrant enhancer activities during gut development that underlie genetic predisposition to pediatric Crohn's diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$431,750September 24, 2021August 31, 2024SETHUPATHY, PRAVEENreporter.nih.gov
CBF-1 role in regulating HIV reservoir in microglial cellsNIHNational Institute of Mental Health2022 to 2023$429,000June 1, 2022May 31, 2026TYAGI, MUDITreporter.nih.gov
Comprehensive Maps of U1 snRNP Binding to Nascent RNA in Human CellsNIHNational Human Genome Research Institute2022$429,000August 12, 2022July 31, 2024BLACK, DOUGLAS Lreporter.nih.gov
Human Embryonic Stem Cell Models for Studying Mechanisms Underlying Changes In Inhibitory Synapses in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$429,000September 11, 2024August 31, 2026SMITH, GARY DANIELreporter.nih.gov
Mechanisms of X chromosome inactivation during human trophoblast differentiation in vitroNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$427,625August 10, 2023July 31, 2025THEUNISSEN, THOROLDreporter.nih.gov
Evaluating Human Pluripotent Stem Cell-Derived Neural Rosette Arrays as a Neural Tube Defect Risk Screening PlatformNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$427,438April 1, 2021September 30, 2023ASHTON, RANDOLPH Sreporter.nih.gov
Engineering Human Organizer To Study Left-Right Symmetry BreakingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$427,340May 4, 2023April 30, 2026WAN, LEO Q.reporter.nih.gov
Identifying human neuron IFN-γ dependent anti-Toxoplasma gondii responsesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$422,125January 12, 2023December 31, 2024KOSHY, ANITAreporter.nih.gov
TMPRSS2 as a potential target for treatments of COVID-19 and respiratory infectious viruses in lungNIHNational Heart, Lung, and Blood Institute2021$421,219September 20, 2021December 31, 2021CHEN, YA-WENreporter.nih.gov
Engineering the OrganizerNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$415,206July 15, 2021June 30, 2024DAVIDSON, LANCE A.reporter.nih.gov
Exploring novel regulatory mechanisms underlying enhancer activation and cell fate transitionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$414,481September 8, 2020August 31, 2023CAO, KAIXIANGreporter.nih.gov
Modeling Histone Demethylase Function in NeurogenesisNIHNational Institute of Neurological Disorders and Stroke2022$414,305July 1, 2022June 30, 2025SRIDHARAN, RUPAreporter.nih.gov
Patterning human forebrain organoids by engineering controlled biochemical microenvironmentNIHNational Institute of Mental Health2022 to 2023$411,450August 1, 2022July 31, 2025SUN, YUBINGreporter.nih.gov
The Regulatory R-loops in Pluripotency, Early Development, and Tissue HomeostasisNIHNational Institute of General Medical Sciences2024$411,250July 5, 2024April 30, 2029HUANG, XINreporter.nih.gov
Examining Microglial Environmental Dependent Transcriptional NetworksNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$410,040September 30, 2018August 31, 2023COUFAL, NICOLE GABRIELEreporter.nih.gov
Microbiome and E. coli O157:H7 infection of human gut tissueNIHNational Institute of Allergy and Infectious Diseases2021$401,250August 15, 2018July 31, 2023WEISS, ALISON A.reporter.nih.gov
Developing approaches for universal organ transplantationNIHOffice of the Director, National Institutes of Health2021$400,392September 1, 2017August 31, 2023LOH, KYLE Mreporter.nih.gov
Systematic Assessment of Combinatorial Transcription Factor ActivityNIHNational Human Genome Research Institute2023$400,000September 1, 2023August 31, 2024HON, GARY CHUNGreporter.nih.gov
In vitro modeling of a mammalian embryonic neural tubeNIHNational Institute of Neurological Disorders and Stroke2021$399,144August 1, 2021December 31, 2022THISSE, BERNARD VICTORreporter.nih.gov
Modulating XIAP for the Treatment of Inflammatory Bowel DiseaseNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$398,938September 1, 2023August 31, 2025BLANDER, JULIE MAGARIANreporter.nih.gov
Contributions of sex chromosomal gene homologues to X monosomyNIHNational Heart, Lung, and Blood Institute2021$398,750April 1, 2018March 31, 2023PINTER, STEFAN F.reporter.nih.gov
Therapeutic potential of targeting DNA repair deficiency in TSCNIHNational Cancer Institute2021 to 2022$398,743July 1, 2021June 30, 2024MACKEIGAN, JEFFREY PAULreporter.nih.gov
Molecular mechanisms underlying cardiac sodium channelopathyNIHNational Heart, Lung, and Blood Institute2021$397,594July 1, 2017June 30, 2022YAZAWA, MASAYUKIreporter.nih.gov
Amnion membrane organ-on-chip for modeling intra-amniotic infectionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$396,838June 21, 2022August 31, 2024FU, JIANPINGreporter.nih.gov
A Stem Cell Based Exosomal Vaccine for the Prevention of CancerNIHNational Cancer Institute2023 to 2024$393,255February 17, 2023January 31, 2026YADDANAPUDI, KAVITHAreporter.nih.gov
Small non-coding RNAs of VZV: role in lytic and latent infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$393,149December 1, 2020November 30, 2023KINCHINGTON, PAUL R.reporter.nih.gov
Maturation of Human Pluripotent Stem Cell-Derived CardiomyocytesNIHNational Heart, Lung, and Blood Institute2021$390,000February 1, 2018January 31, 2023XU, CHUNHUIreporter.nih.gov
Defining mechanisms of Zika-virus associated microcephaly: cell population dynamics and gene expression in infected human cerebral organoids and neural progenitor cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$389,880July 23, 2021September 5, 2022OCWIEJA, KAREN EMILYreporter.nih.gov
Using Syntenic Gapped-kmer Composition to Detect Conserved Enhancers where Sequence Alignment FailsNIHNational Human Genome Research Institute2021$388,975September 24, 2021April 30, 2024BEER, MICHAEL Areporter.nih.gov
Regulation of glioblastoma cells by GABAergic neurons in human organoid-tumor chimerasNIHNational Cancer Institute2023 to 2024$386,799April 6, 2023March 31, 2025SHCHEGLOVITOV, OLEKSANDRreporter.nih.gov
Elucidating the role of CHI3L1/YKL-40 in Alzheimer's diseaseNIHNational Institute on Aging2023$385,717September 15, 2023August 31, 2024HUANG, YU-WEN ALVINreporter.nih.gov
Improving human pluripotent stem cell derived beta cell transplantation using genetic lineage tracing.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$385,420September 30, 2018December 31, 2022RUSS, HOLGER A.reporter.nih.gov
MOLECULAR CONSEQUENCES OF TELOMERASE DYSFUNCTION DURING HEMATOPOIETIC DEVELOPMENTNIHNational Heart, Lung, and Blood Institute2021$381,250August 1, 2017May 31, 2023BATISTA, LUIS FRANCISCO ZIRNBERGERreporter.nih.gov
Analysis of the Molecular Machinery Regulating Gene Expression during Vertebrate DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$381,119February 28, 2020January 31, 2023BEAUDOIN, JEAN-DENISreporter.nih.gov
Characterizing genetic modifiers in tumor burden of Tuberous Sclerosis ComplexNIHNational Cancer Institute2021 to 2024$373,592March 1, 2021November 27, 2024VAUGHAN, ROBERT MARKreporter.nih.gov
Modeling NDE1 function in dysregulated brain development using a microfluidic CNS modelNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$371,362May 15, 2023April 30, 2025FU, JIANPINGreporter.nih.gov
Genetic regulation of embryonic head mesenchyme patterningNIHNational Institute of Dental & Craniofacial Research2024$366,275April 1, 2017August 31, 2025JEONG, JUHEEreporter.nih.gov
Optogenetic and Chemogenetic Dissection of Cell TransplantsNIHNational Institute of Neurological Disorders and Stroke2022$361,165May 4, 2022April 30, 2025SUBRAMANIAN, THYAGARAJANreporter.nih.gov
DAPC structural adaption in regulating nanotopography-responsive myotube orientationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$354,222September 20, 2023August 31, 2025SHEN, WEIreporter.nih.gov
Targeting Dystroglycanopathies using Pluripotent-derived Myogenic ProgenitorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$353,874May 10, 2017March 31, 2022PERLINGEIRO, RITA C. R.reporter.nih.gov
Optogenetic and Chemogenetic Dissection of Cell TransplantsNIHNational Institute of Neurological Disorders and Stroke2021$351,912July 1, 2018October 31, 2021SUBRAMANIAN, THYAGARAJANreporter.nih.gov
Interrogating functional and molecular properties of PAX7+ putative skeletal muscle stem/progenitor cells derived from human iPSCs of healthy donors and Duchenne muscular dystrophy patientsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$348,502March 1, 2017February 28, 2022LEE, GABSANGreporter.nih.gov
Long noncoding RNAs regulating endoderm differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$347,221August 25, 2017July 31, 2022MULLEN, ALAN Creporter.nih.gov
Novel Highly Regenerative and Scalable Progenitor Cell Exosomes for Treating Peripheral Artery DiseaseNIHNational Heart, Lung, and Blood Institute2023$340,956September 1, 2023April 30, 2025LEE, JI EUNreporter.nih.gov
Novel Autonomous Roles of CNS AngiogenesisNIHNational Institute of Neurological Disorders and Stroke2021$339,867September 30, 2017July 31, 2023VASUDEVAN, ANJUreporter.nih.gov
Controlled generation of human embryoids using optogeneticsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$336,254September 8, 2022August 31, 2024FU, JIANPINGreporter.nih.gov
Reconstruction and Regulation of Neural Circuitry by Human NeuronsNIHNational Institute of Neurological Disorders and Stroke2021$334,688December 15, 2016November 30, 2022ZHANG, SU-CHUNreporter.nih.gov
Computational approaches for comparative regulatory genomics to decipher long-range gene regulationNIHNational Human Genome Research Institute2021$332,892September 17, 2018June 30, 2024ROY, SUSHMITAreporter.nih.gov
Embryonic stem cell self-renewalNIHNational Institute of General Medical Sciences2021$330,000August 1, 2018April 30, 2022YING, QILONGreporter.nih.gov
Monitoring and increasing resilience of stem cell derived pancreatic islet cell graftsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$324,998July 20, 2024June 30, 2025DIGOVICH, CATHERINEreporter.nih.gov
Transcriptional and Epigenetic Control of Pluripotency and Development by Zfp281NIHNational Institute of General Medical Sciences2021$324,000August 6, 2018April 30, 2023WANG, JIANLONGreporter.nih.gov
Investigating the cause of APOE4-associated microglial activation and its resulting neurotoxicity of tauopathy-afflicted neuronsNIHNational Institute on Aging2021 to 2023$320,904February 15, 2019November 30, 2023NURIEL, TALreporter.nih.gov
The Mechanical Properties of the Brain and Their Effect on Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$312,744August 15, 2021June 30, 2023GU, LUOreporter.nih.gov
Function of stimulus-induced MeCP2 phosphorylationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$311,125April 1, 2010April 30, 2024CHANG, QIANGreporter.nih.gov
Regulatory Mechanisms of Cardiomyocyte Lineage SpecificationNIHNational Heart, Lung, and Blood Institute2021$310,000December 8, 2017November 30, 2022CHI, NEIL Creporter.nih.gov
Ultra-high resolution 3D genome maps for multiple human tissuesNIHOffice of the Director, National Institutes of Health2024$308,658September 5, 2024September 4, 2025LIU, JIEreporter.nih.gov
Mechanisms of heterochromatin replicationNIHNational Institute of General Medical Sciences2021$301,059January 1, 2018December 31, 2022SMOLKA, MARCUSreporter.nih.gov
Real-time intracellular monitoring of microRNAs in human stem cell-derived insulin producing organoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$300,000September 6, 2021August 31, 2022DIGOVICH, CATHERINEreporter.nih.gov
Self-organizing synthetic human lungs on microchips to fight infection by RSVNIHNational Institute of Allergy and Infectious Diseases2023$300,000May 22, 2023April 30, 2024ETOC, FREDreporter.nih.gov
Craniofacial cartilage differentiation from human neural crest stem cells in 3D culturesNIHNational Institute of Dental & Craniofacial Research2024$294,000September 16, 2024September 15, 2026GRIMES, MARK LINDSAYreporter.nih.gov
Investigating the mechanisms of a multi-state model of Wnt signalingNIHNational Institute of General Medical Sciences2021$293,082April 1, 2017March 31, 2023BRAFMAN, DAVID Areporter.nih.gov
Elucidating the mechanisms of intrinsic stem cell resistance to virus infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$275,998September 2, 2019August 5, 2022WU, XIANFANGreporter.nih.gov
Combinatory Effects of Genetic Variants in Eosinophilic EsophagitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$260,666August 2, 2021June 30, 2023SHODA, TETSUOreporter.nih.gov
Development of allele-specific protein-based therapeutic targeting the pathogenic RNA associated with Spinocerebellar ataxia type 3NIHNational Institute of Neurological Disorders and Stroke2022$259,142August 19, 2022August 18, 2024RUIZ, JOSEPH C.reporter.nih.gov
High throughput molecular screen for environmental epigenetic modifiers in brain development and ASDNIHNational Institute of Environmental Health Sciences2021 to 2023$254,250July 1, 2018February 29, 2024EYRING, KATHERINEreporter.nih.gov
Mechanistic modeling of epigenetic modifier mutations in human pluripotent stem cell-derived immune cellsNIHNational Institute of Allergy and Infectious Diseases2022$253,500February 1, 2022September 30, 2022BYUN, MINJIreporter.nih.gov
Enteroendocrine Regulation of Intestinal MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$252,598September 1, 2021July 31, 2023MCCAULEY, HEATHER Areporter.nih.gov
Changes in L-type calcium channels during aging in the heart's pacemakerNIHNational Institute on Aging2021$248,926September 15, 2019May 31, 2023MORENO, CLAUDIA MARCELAreporter.nih.gov
Mapping and prediction of quantitative transcription factor dosage effects to understand variation in craniofacial morphology and diseaseNIHNational Institute of Dental & Craniofacial Research2023 to 2024$247,554June 1, 2023July 31, 2024NAQVI, SAHINreporter.nih.gov
Using human intestinal organoids to model IBD pathogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$242,250September 16, 2020August 31, 2022KLEIN, OPHIR Dreporter.nih.gov
Inducible Hair Cell Degeneration in Human Inner Ear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2021$237,750April 1, 2020March 31, 2023HASHINO, ERIreporter.nih.gov
VRC: A Stem Cell-Based Treatment Strategy for Laser-Induced Permanent Retinal DamagesNIHNational Eye Institute2021$236,900September 1, 2019June 30, 2023THOMAS, BIJU BLAVADYreporter.nih.gov
Role of ontogeny and niche on human macrophage developmentNIHNational Institute of Allergy and Infectious Diseases2021$236,250February 7, 2020January 31, 2022LAVINE, KORY J.reporter.nih.gov
A Molecular Signaling Pathway Underlying Differential Predisposition of ApoE4 Genotype to Alzheimer's DiseaseNIHNational Institute on Aging2021$232,097July 15, 2019June 30, 2022HUANG, YU-WEN ALVINreporter.nih.gov
Development of a fluidic chip model of PKD to elucidate cystogenic signals using kidney organoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$215,628September 15, 2022September 14, 2024MORIZANE, RYUJIreporter.nih.gov
Evaluating teratogenic risk of anti-seizure medications in single-rosette brain organoidsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$214,500September 20, 2021August 31, 2023TIDBALL, ANDREW Mreporter.nih.gov
Pooled Optical Screens of Synaptic FunctionNIHNational Institute of Mental Health2021$213,750January 15, 2020December 31, 2022FARHI, SAMOUILreporter.nih.gov
Function of SF3B4 in neural crest developmentNIHNational Institute of Dental & Craniofacial Research2021 to 2023$212,364September 1, 2021August 31, 2024GRIFFIN, CASEYreporter.nih.gov
snoRNA31 is critical for human cell-intrinsic immunity to HSV-1 in the central nervous systemNIHNational Institute of Allergy and Infectious Diseases2021$211,875February 12, 2020January 31, 2022ZHANG, SHEN-YINGreporter.nih.gov
Systemic Regulation of ER ProteostasisNIHNational Institute on Aging2021 to 2023$209,964June 1, 2021May 31, 2024TSUI, CHUNG YIN KIMBERLYreporter.nih.gov
Transcriptional regulators of iris muscle cell developmentNIHNational Eye Institute2021$204,308January 1, 2020September 30, 2022BLENKINSOP, TIMOTHY A.reporter.nih.gov
The role of the transcriptional repressor ZEB2 in human neural crest cell formation and craniofacial pathologyNIHNational Institute of Dental & Craniofacial Research2021 to 2022$198,956September 1, 2020August 31, 2024CHARNEY, REBEKAHreporter.nih.gov
Analysis of environmentally-sensitive epigenetic machinery during osteogenic differentiationNIHNational Institute of Environmental Health Sciences2021 to 2022$196,332December 15, 2020August 31, 2022SPARKS, NICOLE RENEEreporter.nih.gov
Mechanistic modeling of epigenetic modifier mutations in human pluripotent stem cell-derived immune cellsNIHNational Institute of Allergy and Infectious Diseases2023$196,250February 1, 2022January 31, 2025BYUN, MINJIreporter.nih.gov
Studying Origin of Human Primordial Germ Cells Using a Synthetic Stem Cell ModelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$195,000February 15, 2020January 31, 2023FU, JIANPINGreporter.nih.gov
VTCN1 regulation of MHC in early human placental developmentNIHNational Institute of Allergy and Infectious Diseases2021$193,750January 31, 2020July 1, 2022SCHUST, DANNY Jreporter.nih.gov
Saturation genome editing approach to functionally test all possible MSH2 variantsNIHNational Cancer Institute2021$191,675December 12, 2019November 30, 2023HEINEN, CHRISTOPHER D.reporter.nih.gov
Exploring the relationship of water flow across the RPE and mutant-MYO7A/Usher 1BNIHNational Eye Institute2021$189,150January 1, 2020December 31, 2023WILLIAMS, DAVID Sreporter.nih.gov
Deciphering polycystin-dependent electric signaling of primary cilia in the renal systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$181,500September 2, 2022August 31, 2025HA, KOTDAJIreporter.nih.gov
Engineering scalable collecting duct networks for functional kidney tissueNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$181,279August 1, 2022December 31, 2024WOLF, KAYLAreporter.nih.gov
Genetically Mediated Hair Cell Degeneration in 3D Inner Ear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2021$178,830April 1, 2017March 31, 2023NELSON, RICK Freporter.nih.gov
A transgenic toolbox to dissect molecular pathologies caused by OTX2 deficiency during ex vivo human ectoderm developmentNIHNational Institute of Neurological Disorders and Stroke2024$169,500December 11, 2023November 30, 2024STADTFELD, MATTHIASreporter.nih.gov
Integrated multi-omics analyses of early mammalian craniofacial developmentNIHNational Institute of Dental & Craniofacial Research2021$164,000January 8, 2020December 31, 2022COTNEY, JUSTIN LEEreporter.nih.gov
Metabolic Regulation of Pancreatic Epithelium DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$159,946August 1, 2022October 18, 2024DAVIS, JEFFREY CARLreporter.nih.gov
Dynamics of FGF and its integration with other pathways during human germ layer differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$159,354July 1, 2022June 30, 2024JO, KYOUNG HAreporter.nih.gov
Administrative Supplement for Direct and rapid control of proteins at scaleNIHNational Institute of General Medical Sciences2022$156,648December 1, 2021May 31, 2024SHALEM, OPHIRreporter.nih.gov
Teratogenicity assessment of new antiviral drugs using 3D morphogenesis modelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$156,500August 10, 2023July 31, 2025MARIKAWA, YUSUKEreporter.nih.gov
Establishment of yolk sac organoids for developmental toxicity assessmentNIHNational Institute of Environmental Health Sciences2024$156,500September 13, 2024August 31, 2026MARIKAWA, YUSUKEreporter.nih.gov
Deep learning models to predict primitive streak formation in human developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$155,512January 1, 2021December 31, 2024ZIKRY, TAREKreporter.nih.gov
Lipid signaling in cardiac development and diseaseNIHNational Heart, Lung, and Blood Institute2021$154,646December 15, 2016November 30, 2022AGUIRRE, AITORreporter.nih.gov
Probing INTS11 as a novel target in neuroblastomaNIHNational Cancer Institute2023 to 2024$154,000March 7, 2023February 28, 2025WAGNER, ERIC Jreporter.nih.gov
Understanding the Transcriptional Networks and Physiologic Adaptations Governing the Clinical Manifestations of Duchenne Muscular DystrophyNIHNational Heart, Lung, and Blood Institute2021 to 2023$152,942July 27, 2020July 26, 2024GARAY, BAYARDO ISIDOREreporter.nih.gov
Investigating Mechanisms of RBM20 Liquid-liquid Phase Separation Driving Cardiomyocyte Physiology and Dilated CardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2023$147,423February 16, 2021March 15, 2023FENIX, AIDAN MANDYreporter.nih.gov
Strategies in Renal Nanomedicine to Impact Treatment Paradigms in Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$146,658September 10, 2019September 9, 2024NAVED, BILAL ABDULLAHreporter.nih.gov
Deciphering Translational Control in Stem CellsNIHNational Institute of General Medical Sciences2023 to 2024$146,256April 1, 2023March 31, 2025JOUNG, JULIAreporter.nih.gov
Coupling between circadian rhythms and redox signaling in stem cell differentiation and adult neurogenesisNIHNational Institute of Mental Health2022 to 2023$146,254December 1, 2020November 30, 2023IASCONE, DANIEL MAXIMreporter.nih.gov
Defining the downstream genetic networks regulated by GATA6 during human cardiogenesis using iPSC and hESC modelsNIHNational Heart, Lung, and Blood Institute2021 to 2022$144,400June 1, 2020May 31, 2023BISSON, JOSEPH Areporter.nih.gov
Retinal Ganglion Cell Subtype Specification in Human Retinal OrganoidsNIHNational Eye Institute2022 to 2024$143,420March 1, 2022February 28, 2025GUY, BRIANreporter.nih.gov
INVESTIGATING THE ROLE OF THE CYTOSKELETON IN NEURODEGENERATIONNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$143,420August 1, 2022July 31, 2025STEPHENS, MORGAN CATHERINEreporter.nih.gov
Chromatin Organization in Glioma InitiationNIHNational Cancer Institute2021 to 2023$142,253January 7, 2021January 6, 2024BREADY, DEVIN MICHAELreporter.nih.gov
Regulation of Invasive Trophoblast Cell Lineage DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$141,570August 2, 2022August 31, 2023VARBERG, KAELA MARGARETreporter.nih.gov
Spatiotemporal regulation of thyroid hormone signaling in cone subtype specification in human retinal organoidsNIHNational Eye Institute2021 to 2023$140,482September 1, 2021August 31, 2024MCNERNEY, CHRISTINA LYNNEreporter.nih.gov
Measuring allele and isoform-specific RBP binding to improve predictive models of RNA splicingNIHNational Institute of General Medical Sciences2021 to 2022$133,576April 1, 2021March 31, 2023SCHERTZER, MEGANreporter.nih.gov
Interrogation of retroelement-derived proteins for functional gene transferNIHNational Cancer Institute2022 to 2024$131,231September 1, 2022August 31, 2025LASH, BLAKEreporter.nih.gov
Defining the OGT Interactive and its Role in X-Linked Intellectual Disability - Corrected Resubmission - Stephen Pre Doc FellowshipNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$130,282January 2, 2020December 31, 2023STEPHEN, HANNAH MICHELLEreporter.nih.gov
Investigating mechanical regulation of nephrogenesis using viscoelastic biomaterials and kidney organoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$127,124August 1, 2022May 31, 2024NERGER, BRYANreporter.nih.gov
next-generation sequencing approaches to identify genotype-phenotype relationships during miRNA tuning of neural crest osteogenesisNIHNational Institute of Dental & Craniofacial Research2023$126,958May 1, 2023April 30, 2025ZUR NIEDEN, NICOLE ISOLDEreporter.nih.gov
Understanding and regulating skeletal muscle progenitor and stem cell states through metabolic and epigenetic modulationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$126,024July 1, 2021June 30, 2024CHIEN, PEGGIE JANEreporter.nih.gov
Generation of human inner ear organoids via genetic programmingNIHNational Institute on Deafness and Other Communication Disorders2022$125,424April 1, 2022July 8, 2022NIE, JINGreporter.nih.gov
Elucidating the impact of FIC-1/FICD-mediated AMPylation on polyglutamine aggregation dynamics and toxicityNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$123,094July 1, 2022June 30, 2025VAN PELT, KATE MATTHYSreporter.nih.gov
Acoustic-transfection using high frequency ultrasound for intracellular delivery of macromolecules into targeted single cellsNIHNational Institute of General Medical Sciences2021$121,563May 1, 2017August 15, 2022YOON, SANGPILreporter.nih.gov
Dissecting the role of Erk signaling dynamics in positioning and coordinating germ layer fatesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$121,111September 1, 2022August 31, 2025BAXTER, NAOMI JESSIEreporter.nih.gov
Toward enhancing organization and defining synaptic connectivity of transplanted human pluripotent stem cell-derived photoreceptor graftsNIHNational Eye Institute2021 to 2023$120,965March 1, 2020June 11, 2023LUDWIG, ALLISON LYNreporter.nih.gov
Human CRISPRa Cardiac Reprogramming: Model Characterization and Epigenetic MechanismsNIHNational Heart, Lung, and Blood Institute2021 to 2023$119,268September 1, 2020November 30, 2023KEEPERS, BENJAMINreporter.nih.gov
Admin Supplement: Identifying the ABCs of xenobiotic metabolism in protecting the germ line lineageNIHNational Institute of Environmental Health Sciences2021 to 2022$116,385December 1, 2018July 31, 2022SCHRANKEL, CATHERINE SARAHreporter.nih.gov
Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's diseaseNIHNational Institute on Aging2021$116,385January 1, 2020November 30, 2022PENG, CHUNTEreporter.nih.gov
Circadian Control of Pancreatic Beta-cell Maturation by Dec1NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$102,718July 22, 2021December 31, 2021ALVAREZ, JUAN Rreporter.nih.gov
Molecular impediments to fate-specifying pioneer factor activity during developmentNIHNational Institute of General Medical Sciences2021$97,999March 3, 2021March 31, 2022MEERS, MICHAEL Preporter.nih.gov
Dissecting GWAS Identified Risk Variants in Parkinson's Disease – Functional Role of GPNMB in the Pathogenesis of PDNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$96,668April 1, 2023March 31, 2025LO BU, RIANAreporter.nih.gov
Loss of nuclear integrity is sufficient to induce age-associated changes and Alzheimer's pathology in hPSC-derived cortical neurons.NIHNational Institute on Aging2021 to 2022$92,788May 13, 2020May 12, 2023MINOTTI, ANDREWreporter.nih.gov
Deciphering the role of XACT lncRNA in human developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$89,594September 1, 2020August 31, 2023AFASIZHEVA, ANNAreporter.nih.gov
Developing Remyelination Strategies for Demyelinating Optic Neuropathies Using Human Pluripotent Stem CellsNIHNational Eye Institute2021$88,947May 1, 2019December 31, 2021CHAMLING, XITIZreporter.nih.gov
Understanding OPA1 mutation-driven dominant optic atrophy using human PSC-derived retinal ganglion cellsNIHNational Eye Institute2021 to 2022$87,805September 30, 2021September 29, 2023POHL, KATHERINE ANNEreporter.nih.gov
Characterizing enhancers regulating transcription factor expression for cell-type specification across neurodevelopmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$86,788September 1, 2021August 31, 2023HONNELL, VICTORIAreporter.nih.gov
Investigating SNX13 in Cerebellar Function and DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$84,345September 18, 2023September 17, 2025SANCHEZ, VANESSA BREANNEreporter.nih.gov
Transcriptional interference through LUTI mRNA expression in developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$83,121November 1, 2020August 31, 2023MORSE, KAITLINreporter.nih.gov
Inferring Gene Regulatory Networks Governing Definitive Endoderm Differentiation from Single Cell RNA Velocity MeasurementsNIHNational Heart, Lung, and Blood Institute2021 to 2023$82,113April 2, 2021May 31, 2023RANEK, JOLENE SARAHreporter.nih.gov
Improving cardiovascular disease modeling using human pluripotent stem cell-derived cardiac fibroblastsNIHNational Heart, Lung, and Blood Institute2021 to 2022$80,633September 1, 2020May 20, 2023KERR, CHARLES MATTHEWreporter.nih.gov
An All Optical Platform for Modeling and Monitoring Early Neurodegeneration in Human Neural CircuitsNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$79,266September 1, 2022August 31, 2024TJAHJONO, NIKKIreporter.nih.gov
Acoustic assembly of patient tumor organoids for modeling cancer immunityNIHNational Institute of Biomedical Imaging and Bioengineering2021$79,250July 1, 2020April 30, 2022GUO, FENGreporter.nih.gov
Investigation of cellular cues for differentiation of ventricular cardiomyocytesNIHNational Heart, Lung, and Blood Institute2022 to 2023$78,595June 1, 2022May 31, 2024HOLMAN, ALYSSA RAEreporter.nih.gov
Human pluripotent stem cell-based assessment of dolutegravir teratogenicityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$78,020August 10, 2020July 31, 2023MARIKAWA, YUSUKEreporter.nih.gov
In vitro molecular interrogation of SSRI antidepressants for teratogenic potentialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$77,750April 1, 2020March 31, 2023MARIKAWA, YUSUKEreporter.nih.gov
The Genetic Basis of Human DNA Replication TimingNIHNational Institute of General Medical Sciences2023$76,340May 1, 2023January 1, 2024KOREN, AMNONreporter.nih.gov
Describing the Networks of Disease-associated Transcription Factors in the Brain.NIHNational Institute of Mental Health2021 to 2022$75,910March 1, 2020October 31, 2022CASELLA, ALEXreporter.nih.gov
Harnessing biophysical cues to spatially organize developing cardiac organoidsNIHNational Heart, Lung, and Blood Institute2024$74,284September 1, 2024August 31, 2027MOLLEY, THOMAS GREGORYreporter.nih.gov
Determining the developmental origins of retinoblastomaNIHNational Cancer Institute2021$72,958April 1, 2019March 31, 2022NORRIE, JACQUELINEreporter.nih.gov
pH dynamics determining DNA binding specificity of FOX transcription factorsNIHNational Institute of General Medical Sciences2022 to 2023$72,899March 1, 2022August 31, 2023KISOR, KYLEreporter.nih.gov
Effect of Pre- and Peri-Implantation Zika Virus Infection on Fetal DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$72,630September 1, 2019August 31, 2022LACKO, LAURETTA A.reporter.nih.gov
Probing schizophrenia associated neurodevelopmental defects in integrated neocortical organoidsNIHNational Institute of Mental Health2021$72,630September 23, 2019September 22, 2022WALSH, RYANreporter.nih.gov
Determining the influence of 3D chromatin structure on human evolutionNIHNational Human Genome Research Institute2021 to 2022$69,946September 16, 2020November 18, 2022HARSHMAN, LANAreporter.nih.gov
Exploring the Role of Notch Signaling in Purkinje Fiber DevelopmentNIHNational Heart, Lung, and Blood Institute2021 to 2022$69,820May 1, 2020August 31, 2022GONZALEZ , DAVID MATTHEWreporter.nih.gov
Dissecting principles of transcription factor bindingNIHNational Institute of General Medical Sciences2021$68,562January 1, 2020December 31, 2021CHEN, AMY FANreporter.nih.gov
Identifying targets that lower APP as a therapeutic strategy for Alzheimer's diseaseNIHNational Institute on Aging2021$68,562September 1, 2020August 31, 2022JOHNSON, JENNIFER LEIGHreporter.nih.gov
MECHANISMS OF CHROMATIN REMODELING DURING EPITHELIAL DEVELOPMENTNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$67,446February 1, 2019January 31, 2022COLLIER, ANNIEreporter.nih.gov
Investigating the role of mesenchymal R-Spondin2 during human lung developmentNIHNational Heart, Lung, and Blood Institute2021 to 2022$64,871July 1, 2020November 11, 2022CONWAY, RENEE FRANCESreporter.nih.gov
The role of VSNL1 in human heart rate regulationNIHNational Heart, Lung, and Blood Institute2023$63,844September 30, 2023June 30, 2024GHAZIZADEH, ZANIARreporter.nih.gov
Investigating the role of the FAIM2 locus in predisposition to childhood obesityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$62,742September 1, 2022December 15, 2023LITTLETON, SHERIDAN HOPEreporter.nih.gov
PRC1-dependent H2A Monoubiquitination During Human CorticogenesisNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$57,734January 1, 2023February 12, 2024RYAN, CHARLES WILLIAMreporter.nih.gov
Improving Brain Organoid Models by Mediating Metabolic DysregulationNIHNational Institute of Mental Health2021$57,142September 17, 2020December 31, 2021ANDREWS, MADELINEreporter.nih.gov
Engineering thick human cardiac tissue constructs with patterned, perfusable microvessels for treatment of myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2022$48,499April 1, 2021June 15, 2022ZEINSTRA, NICOLEreporter.nih.gov
Novel targets in the cholesterol biosynthesis pathway for enhanced oligodendrocyte formationNIHNational Institute of Mental Health2021$47,773July 1, 2018May 15, 2022HUBLER, ZITA MARIA LUPEreporter.nih.gov
Understanding the Role of CLP1 in Mammalian mRNA Transcription and CleavageNIHNational Institute of Neurological Disorders and Stroke2021$46,036July 1, 2021June 30, 2022LAFORCE, GENEVAreporter.nih.gov
Identifying Intrinsic Regulators of Areal Patterning in The Neocortex by Single-Cell RNA-seq and Organoid ArealizationNIHNational Institute of Neurological Disorders and Stroke2021$43,401August 1, 2020July 31, 2022SANDOVAL ESPINOSA, CARMEN DEL ROCIOreporter.nih.gov
Molecular impediments to fate-specifying pioneer factor activity during developmentNIHNational Institute of General Medical Sciences2022$38,030March 3, 2021August 31, 2022MEERS, MICHAEL Preporter.nih.gov
Role of pH on Lineage Fate during Pluripotent Stem Cell DifferentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$37,838July 15, 2019May 29, 2022LU, VIVIANreporter.nih.gov
Engineering stem cell-derived T cells for immunotherapyNIHNational Cancer Institute2021$36,901January 1, 2020December 31, 2021CHANG, PATRICK Creporter.nih.gov
Modeling Prenatal COVID-19 Exposure Using Human Cortical Organoids and Mouse ModelsNIHNational Institute of Neurological Disorders and Stroke2022$36,752June 1, 2022MCMAHON, COURTNEYreporter.nih.gov
Enhancing Safety and Efficacy of Stem-Cell Derived Islet Transplantation using CRISPR-Mediated Genome EngineeringNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$36,700August 1, 2024December 16, 2024CHU, SIMONreporter.nih.gov
Regionalized Human Motor Neuron TherapiesNIHNational Institute of Neurological Disorders and Stroke2021$35,229September 14, 2018September 30, 2022IYER, NISHAreporter.nih.gov
Probing the human pancreatic and islet matrisomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$34,546April 15, 2020April 14, 2022TREMMEL, DANIEL Mreporter.nih.gov
Myosin Activation as a Novel Therapeutic Strategy for Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$29,564September 1, 2021March 27, 2022HELMS, LOUISA Mreporter.nih.gov
The Role of Gamma-Secretase in Human Neuronal PhysiologyNIHNational Institute on Aging2021$25,238September 16, 2019March 15, 2022ESSAYAN-PEREZ, SOFIAreporter.nih.gov
The role of autism susceptibility genes in the 16p11.2 locus on the development and function of human stem cell-derived neural cellsNIHNational Institute of Mental Health2021$22,590February 1, 2021July 31, 2021WELLS, MICHAEL FREDERICKreporter.nih.gov
Engineered Cardiac Tissue with Biomimetic Architecture and VasculatureNIHNational Heart, Lung, and Blood Institute2021$15,482March 16, 2017March 16, 2021ARAKAWA, CHRISTOPHER KENJIreporter.nih.gov
Dissection of the transcriptional network of human primordial germ cellsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$14,100August 1, 2019May 31, 2021REIJO PERA, RENEE Areporter.nih.gov
Investigating the Role of Shear Stress in Coronary Artery DevelopmentNIHNational Heart, Lung, and Blood Institute2021$10,651September 1, 2020September 30, 2021WILLIAMS, IAN MILLERreporter.nih.gov
Single-cell gene expression dynamics during neurogenesisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$7,246April 1, 2019May 31, 2021BURKHARDT, DANIELreporter.nih.gov
Investigating nephron-vascular crosstalk in tissue patterning and maturationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$6,856September 30, 2020October 4, 2021RYAN, ANNE REGINAreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California, San DiegoLa Jolla, CA23$33.8 million0$0
Stanford UniversityStanford, CA23$25.2 million0$0
University of Michigan at Ann ArborAnn Arbor, MI27$19.1 million0$0
Columbia University Health SciencesNew York, NY15$18.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA5$17.6 million0$0
Johns Hopkins UniversityBaltimore, MD17$15.1 million0$0
University of California Los AngelesLos Angeles, CA21$15.1 million0$0
University of Wisconsin-MadisonMadison, WI17$15.1 million0$0
University of WashingtonSeattle, WA15$14 million0$0
Boston Children's HospitalBoston, MA6$13.9 million0$0
Yale UniversityNew Haven, CT7$12.9 million0$0
Weill Medical Coll of Cornell UnivNew York, NY13$12.9 million0$0
University of California, San FranciscoSan Francisco, CA16$11.9 million0$0
University of PennsylvaniaPhiladelphia, PA6$11.4 million0$0
Clemson UniversityClemson, SC1$10.8 million0$0
Baylor College of MedicineHouston, TX9$10.7 million0$0
Rockefeller UniversityNew York, NY8$9.3 million0$0
Harvard UniversityCambridge, MA7$9.2 million0$0
Carnegie Mellon UniversityPittsburgh, PA1$8.3 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA6$8.3 million0$0
University of California-BerkeleyBerkeley, CA6$8 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH7$7.9 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY7$7.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC6$6.7 million0$0
Harvard Medical SchoolBoston, MA4$6.7 million0$0
Massachusetts General HospitalBoston, MA6$6.5 million0$0
University of Connecticut SCH of Med/dntFarmington, CT9$6.3 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY6$6.2 million0$0
Whitehead Institute for Biomedical ResCambridge, MA3$5.7 million0$0
Duke UniversityDurham, NC4$5.6 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA2$5.5 million0$0
University of MinnesotaMinneapolis, MN5$5.1 million0$0
Jackson LaboratoryBar Harbor, ME3$4.8 million0$0
Washington UniversitySaint Louis, MO5$4.7 million0$0
University of Colorado DenverAurora, CO4$4.5 million0$0
ST. Jude Children's Research HospitalMemphis, TN4$4.4 million0$0
University of California-Santa CruzSanta Cruz, CA2$4.3 million0$0
Broad Institute, Inc.Cambridge, MA5$4.2 million0$0
University of ArizonaTucson, AZ4$4.1 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL2$4 million0$0
California Institute of TechnologyPasadena, CA2$3.9 million0$0
Indiana University IndianapolisIndianapolis, IN7$3.6 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA3$3.3 million0$0
Altius Institute for Biomedical SciencesSeattle, WA1$3.1 million0$0
Albert Einstein College of MedicineBronx, NY4$3.1 million0$0
Vanderbilt UniversityNashville, TN3$2.9 million0$0
University of Southern CaliforniaLos Angeles, CA5$2.8 million0$0
Dartmouth CollegeHanover, NH2$2.7 million0$0
Regenerative Research FoundationAlbany, NY1$2.6 million0$0
Columbia UniversityNew York, NY1$2.6 million0$0
Brigham and Women's HospitalBoston, MA2$2.4 million0$0
Tufts UniversityMedford, MA1$2.4 million0$0
Minutia, Inc.Oakland, CA3$2.4 million0$0
Oregon Health & Science UniversityPortland, OR1$2.3 million0$0
Morgridge Institute for Research, Inc.Madison, WI1$2.3 million0$0
University of CincinnatiCincinnati, OH4$2.3 million0$0
University of WyomingLaramie, WY1$2.3 million0$0
University of Massachusetts AmherstAmherst, MA2$2.2 million0$0
University of RochesterRochester, NY3$2.2 million0$0
Ohio State UniversityColumbus, OH2$2.1 million0$0
Tulane University of LouisianaNew Orleans, LA1$1.8 million0$0
Case Western Reserve UniversityCleveland, OH5$1.8 million0$0
University of LouisvilleLouisville, KY2$1.8 million0$0
University of FloridaGainesville, FL1$1.7 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA1$1.7 million0$0
Cornell UniversityIthaca, NY4$1.6 million0$0
Michigan State UniversityEast Lansing, MI4$1.6 million0$0
University of California-Santa BarbaraSanta Barbara, CA2$1.5 million0$0
Medical College of WisconsinMilwaukee, WI1$1.5 million0$0
Scripps Research Institute, theLa Jolla, CA1$1.5 million0$0
University of Illinois at ChicagoChicago, IL1$1.5 million0$0
University of IowaIowa City, IA1$1.5 million0$0
University of VirginiaCharlottesville, VA2$1.4 million0$0
Palo Alto Veterans Instit for ResearchPalo Alto, CA1$1.4 million0$0
University of California-IrvineIrvine, CA3$1.4 million0$0
Fred Hutchinson Cancer CenterSeattle, WA2$1.3 million0$0
Digital Science and Research Solutions, Inc.Cambridge, MA1$1.2 million0$0
Brown UniversityProvidence, RI3$1.2 million0$0
University of UtahSalt Lake City, UT2$1.1 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA1$1.1 million0$0
University of Calif-Lawrenc Berkeley LabBerkeley, CA1$1.1 million0$0
Thomas Jefferson UniversityPhiladelphia, PA2$1.1 million0$0
Arizona State UniversityScottsdale, AZ2$1 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA2$943,3180$0
Northwestern University at ChicagoChicago, IL2$936,6580$0
Princeton UniversityPrinceton, NJ1$896,5880$0
Children's Hospital of Los AngelesLos Angeles, CA1$884,8240$0
Salk Institute for Biological StudiesLa Jolla, CA1$865,0400$0
University of Georgia Research Foundation IncAthens, GA2$843,4640$0
Masonic Medical Research Laboratory, INCUtica, NY1$825,5730$0
Beckman Research Institute/city of HopeDuarte, CA1$816,4160$0
Mclean HospitalBelmont, MA1$801,2040$0
Louisiana State University Agricultural CenterBaton Rouge, LA1$761,3820$0
New York Genome CenterNew York, NY2$712,5760$0
Epitor Therapeutics, Inc.New York, NY1$698,4590$0
University of California - MercedMerced, CA1$696,0170$0
Axent Biosciences Inc.Berkeley, CA1$685,8390$0
Aruna Biomedical, Inc.Athens, GA1$679,4110$0
Scripps FloridaJupiter, FL1$662,1260$0
William Marsh Rice UniversityHouston, TX1$645,5490$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20252$2,510,0540$0
2024142$70,425,1930$0
2023234$101,511,6330$0
2022331$152,984,5520$0
2021387$190,331,9020$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)RFA-DK-27-125NIH93.847November 6, 2026Not listedSame assistance listing 93.847 as 70 awards here
Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)RFA-DK-27-112NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 70 awards here
Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)RFA-DK-27-139NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 70 awards here
Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)RFA-DK-27-122NIH93.847November 17, 2026Not listedSame assistance listing 93.847 as 70 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.847December 4, 2026Not listedSame assistance listing 93.847 as 70 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.847January 5, 2027Not listedSame assistance listing 93.847 as 70 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.847January 7, 2027Not listedSame assistance listing 93.847 as 70 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.847January 15, 2027$350,000Same assistance listing 93.847 as 70 awards here
Diabetes Research Centers (P30 Clinical Trial Optional)RFA-DK-26-310NIH93.847January 27, 2027$1 millionSame assistance listing 93.847 as 70 awards here
NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)RFA-DK-28-114NIH93.847January 28, 2027Not listedSame assistance listing 93.847 as 70 awards here
KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)RFA-DK-28-312NIH93.847January 30, 2027Not listedSame assistance listing 93.847 as 70 awards here
KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)RFA-DK-28-313NIH93.847January 30, 2027Not listedSame assistance listing 93.847 as 70 awards here
Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)RFA-DK-27-119NIH93.847February 10, 2027$750,000Same assistance listing 93.847 as 70 awards here
Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)RFA-DK-28-116NIH93.847February 10, 2027Not listedSame assistance listing 93.847 as 70 awards here
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)RFA-DK-27-108NIH93.847March 10, 2027$500,000Same assistance listing 93.847 as 70 awards here
Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)RFA-DK-28-115NIH93.847March 10, 2027Not listedSame assistance listing 93.847 as 70 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.847April 5, 2027Not listedSame assistance listing 93.847 as 70 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.847April 5, 2027Not listedSame assistance listing 93.847 as 70 awards here
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)RFA-OD-25-003NIH93.847April 9, 2027$200,000Same assistance listing 93.847 as 70 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIH93.847May 7, 2027Not listedSame assistance listing 93.847 as 70 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.