Data / Research funding / Sepsis
Sepsis: 801 NIH awards ($884.5M) to 221 organizations
801 NIH awards ($884.5M) in the NIH spending category Sepsis, to 221 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
The 500 largest of 801 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE) | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $16,153,090 | May 1, 2023 | April 30, 2029 | SELF, WESLEY H | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $12,717,344 | August 13, 2021 | July 31, 2026 | WATT, KEVIN M | reporter.nih.gov |
| Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis Pathobiology | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $8,479,606 | May 1, 2021 | April 30, 2027 | EFRON, PHILIP A | reporter.nih.gov |
| 1/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $8,010,367 | September 16, 2020 | August 31, 2025 | BOECKH, MICHAEL J | reporter.nih.gov |
| Molecular and Immunologic Analysis of the Pathobiology of Human Anthrax | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $6,892,629 | September 15, 2004 | August 31, 2025 | FARRIS, A DARISE | reporter.nih.gov |
| Combatting AntiMicrobial Resistance in Africa Using Data Science (CAMRA) | NIH | Fogarty International Center | 2021 to 2025 | $6,419,538 | September 15, 2021 | June 30, 2027 | HAPPI, CHRISTIAN T. | reporter.nih.gov |
| Short Course Versus Standard Course Antifungal Therapy for Pediatric Candidemia: A Multi-Center Randomized Controlled Trial | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $5,640,067 | August 5, 2022 | July 31, 2029 | STEINBACH, WILLIAM J | reporter.nih.gov |
| SHIPSS: Stress Hydrocortisone In Pediatric Septic Shock | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2024 | $5,170,974 | July 1, 2019 | June 30, 2025 | AGUS, MICHAEL SD | reporter.nih.gov |
| Single-cell genomic profiling to identify immune signatures of bacterial sepsis in humans | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,956,855 | March 3, 2021 | February 28, 2027 | GOLDBERG, MARCIA B | reporter.nih.gov |
| Mechanisms of integrin signaling and a new anti-platelet/anti-inflammatory approach | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,858,002 | June 1, 2020 | May 31, 2027 | DU, XIAOPING | reporter.nih.gov |
| Bloodstream infection detection directly on whole blood | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,982,842 | June 1, 2016 | June 30, 2027 | CELEDON, ALFREDO ANDRES | reporter.nih.gov |
| Novel Pediatric Sepsis Criteria and Clinical Decision Support Tools | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,901,596 | September 1, 2021 | May 31, 2030 | BENNETT, TELLEN | reporter.nih.gov |
| Investigating Individual Susceptibility and Host Response in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,880,499 | August 19, 2022 | July 31, 2029 | MEYER, NUALA JENNINGS | reporter.nih.gov |
| HLA Fine Mapping to Elucidate S. aureus Susceptibility | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,757,863 | September 17, 2021 | August 31, 2026 | FOWLER, VANCE G. | reporter.nih.gov |
| Evaluating Resolution Mechanisms for Infectious Inflammation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,584,466 | April 1, 2021 | March 31, 2027 | SERHAN, CHARLES NICHOLAS | reporter.nih.gov |
| Regulation of LPS-responses by ZBP1 | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,578,088 | September 22, 2021 | June 15, 2026 | POLTORAK, ALEXANDER | reporter.nih.gov |
| Targeting the Intestinal Mucosa and Microbiome to Prevent Neonatal Late-onset Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,526,115 | August 1, 2021 | July 31, 2027 | WEAVER, CASEY T | reporter.nih.gov |
| Development of anti-LPS therapeutic antibodies for the treatment of Pseudomonas aeruginosa infections | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $3,521,872 | August 1, 2024 | July 31, 2029 | BARBIER, MARIETTE | reporter.nih.gov |
| I-TRANSFER Improving TRansitions ANd outcomeS oF sEpsis suRvivors | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,506,198 | September 25, 2015 | November 30, 2026 | BOWLES, KATHRYN HELENE | reporter.nih.gov |
| PROMPT BOLUS admin supplement | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $3,504,025 | September 11, 2020 | August 31, 2026 | BALAMUTH, FRANCES B | reporter.nih.gov |
| Large-scale Implementation of Community Co-led Maternal Sepsis Care Practices to Reduce Morbidity and Mortality from Maternal Infection | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $3,471,058 | September 30, 2021 | June 30, 2027 | ALLEN, TERRENCE KELBURN | reporter.nih.gov |
| Novel bi-specific immunotherapeutic against high-threat Gram-negative pathogens | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $3,410,042 | February 21, 2019 | January 31, 2025 | PERLIN, DAVID S | reporter.nih.gov |
| Mechanisms of Immune Dysfunction after Trauma and Surgical Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,405,189 | June 1, 2018 | May 31, 2028 | BILLIAR, TIMOTHY R | reporter.nih.gov |
| Stratifying Patient Immune Endotypes in Sepsis (SPIES Study) | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $3,390,895 | September 5, 2020 | June 30, 2026 | MAILE, ROBERT | reporter.nih.gov |
| Neuroinflammatory mechanisms underlying sepsis-induced cognitive dysfunction | NIH | National Institute on Aging | 2022 to 2025 | $3,346,228 | September 15, 2022 | August 31, 2027 | HARRISON, FIONA EDITH | reporter.nih.gov |
| Predictive informatics monitoring in the Neonatal Intensive Care Unit | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,311,236 | July 10, 2014 | April 30, 2027 | FAIRCHILD, KAREN D | reporter.nih.gov |
| Culture and amplification-free bacterial sepsis diagnosis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,298,494 | June 9, 2023 | May 31, 2027 | CELEDON, ALFREDO ANDRES | reporter.nih.gov |
| A Phase 1b Study of Inhaled CO for the Treatment of Sepsis-Induced ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $3,249,318 | September 15, 2020 | April 30, 2025 | PLATAKI, MARIA | reporter.nih.gov |
| The epigenetic regulation of inflammation in tissue repair and vascular disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $3,217,378 | July 1, 2023 | June 30, 2030 | GALLAGHER, KATHERINE ANN | reporter.nih.gov |
| Defining human and mouse non-canonical inflammasome responses to LPS | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $3,204,624 | July 24, 2025 | June 30, 2029 | SHIN, SUNNY | reporter.nih.gov |
| Development of peptide nucleic acid antibiotics | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $3,164,488 | February 10, 2021 | January 31, 2025 | ARYA, DEV PRIYA | reporter.nih.gov |
| Immunomodulation by splenic megakaryocytes and platelets in sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,151,437 | June 7, 2022 | May 31, 2027 | LOONEY, MARK ROBERTS | reporter.nih.gov |
| Optimizing anti-microbial immunity by targeting Sts-1 | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $3,125,627 | July 23, 2025 | June 30, 2029 | CARPINO, NICHOLAS A | reporter.nih.gov |
| Mechanism of Immune Dysfunction and Morbid Outcomes in Response to Shock/Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,116,857 | May 1, 2016 | October 31, 2026 | AYALA, ALFRED | reporter.nih.gov |
| Direct-from-specimen identification of pathogens common in endocarditis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,051,028 | January 4, 2018 | December 31, 2026 | SINGER, ALON | reporter.nih.gov |
| Direct detection and identification of antimicrobial resistance genes in bloodstream infections | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $3,050,000 | August 9, 2022 | July 31, 2025 | SINGER, ALON | reporter.nih.gov |
| Diagnostic tool for assessment and tracking of microbial load in bloodstream infections | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,031,639 | June 23, 2023 | May 31, 2027 | SINGER, ALON | reporter.nih.gov |
| Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated Pneumonia | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,027,494 | July 1, 2023 | June 30, 2028 | NIZET, VICTOR | reporter.nih.gov |
| Host Directed Orynotide for MDR Gram Negative Bacterial Infections | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,025,760 | July 21, 2023 | June 30, 2028 | SCHAAL, JUSTIN BLAINE | reporter.nih.gov |
| MAb Passive Vaccination against Acinetobacter baumannii | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $3,021,383 | September 25, 2017 | August 31, 2027 | SPELLBERG, BRAD J | reporter.nih.gov |
| Adaptation of vancomycin-resistant enterococci during bloodstream infection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,020,097 | June 3, 2022 | May 31, 2027 | VAN TYNE, DARIA N | reporter.nih.gov |
| Mechanisms of Radiation-Induced Innate Immune Dysfunction and Its Countermeasures | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,005,089 | July 21, 2022 | May 31, 2027 | WANG, PING | reporter.nih.gov |
| Massively Multiplexed dsDNA Invasion Arrays | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $3,000,000 | April 14, 2021 | March 31, 2025 | SINGER, ALON | reporter.nih.gov |
| An Integrated Device for Rapid Bacteremia Diagnosis Direct from Whole Blood | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $3,000,000 | July 1, 2016 | March 31, 2025 | SINGER, ALON | reporter.nih.gov |
| Commercialization Readiness Pilot (CRP) program support for: An Integrated Device for identification of bloodstream infections directly from blood | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $3,000,000 | March 3, 2022 | February 28, 2026 | SINGER, ALON | reporter.nih.gov |
| Highly Multiplexed Single Molecule Tethering | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,999,694 | August 17, 2023 | July 31, 2027 | CELEDON, ALFREDO ANDRES | reporter.nih.gov |
| Development of a Dual-Targeting ClpP Activating Antibiotic | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,999,619 | September 1, 2023 | August 31, 2026 | LAFLEUR, MICHAEL | reporter.nih.gov |
| Commercialization Readiness Pilot (CRP) program support for: Direct-from-specimen identification of pathogens common in endocarditis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,997,234 | June 20, 2023 | May 31, 2027 | SINGER, ALON | reporter.nih.gov |
| Mechanistic role of membrane pore formation in lung-endothelial barrier failure due to blood-borne pathogens. | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,988,753 | June 1, 1985 | July 31, 2027 | BHATTACHARYA, JAHAR | reporter.nih.gov |
| Direct from blood identification of bloodstream infections in newborns | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,981,785 | August 1, 2022 | July 31, 2025 | SINGER, ALON | reporter.nih.gov |
| Control of Type I Interferon Production in Response to Candida albicans | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,947,724 | April 10, 2020 | March 31, 2026 | VYAS, JATIN M | reporter.nih.gov |
| Transfusion and Organ Dysfunction in Pediatric Septic Shock (TROPICS) study | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,942,460 | March 20, 2022 | February 28, 2027 | MUSZYNSKI, JENNIFER | reporter.nih.gov |
| Changing Cultures in Sepsis: Rapid single-cell pathogen identification and antibiotic susceptibility testing directly from whole blood | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,910,960 | June 15, 2020 | May 31, 2026 | YANG, SAMUEL | reporter.nih.gov |
| Calpain/talin/MLCP axis in pulmonary endothelial barrier regulation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,873,437 | September 1, 2022 | August 31, 2026 | VERIN, ALEXANDER D | reporter.nih.gov |
| Assessment of Implementation Methods in Sepsis and Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,868,952 | July 15, 2022 | June 30, 2027 | LEVY, MITCHELL M | reporter.nih.gov |
| Renal Metabolism in AKI | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,833,514 | September 15, 2025 | September 14, 2029 | SINGH, PRABHLEEN | reporter.nih.gov |
| Novel Approaches to Maintaining Organ Function in Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,796,919 | June 1, 2016 | June 30, 2027 | WANG, PING | reporter.nih.gov |
| Dissecting the molecular mechanisms of lung injury during mechanical ventilation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,791,533 | February 15, 2021 | January 31, 2027 | ENGLERT, JOSHUA A | reporter.nih.gov |
| EnCoRe MOMS: Engaging Communities to Reduce Morbidity from Maternal Sepsis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,790,846 | September 21, 2022 | September 20, 2026 | GOFFMAN, DENA | reporter.nih.gov |
| Vertically transferred antibodies protect babies from Escherichia coli infection | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $2,790,604 | September 11, 2025 | August 31, 2029 | WAY, SING SING | reporter.nih.gov |
| Continuous Therapeutic Drug Monitoring of Antibiotics in CRRT | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,752,374 | February 1, 2021 | January 31, 2026 | MOHAN, SUMIT | reporter.nih.gov |
| Complement C1q and sepsis associated fatalities | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,739,876 | July 1, 2022 | June 30, 2027 | KIM, MINSOO | reporter.nih.gov |
| Modeling informatics data to track maternal risk and care quality | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,737,921 | September 8, 2022 | August 31, 2027 | FRIEDMAN, ALEXANDER M | reporter.nih.gov |
| An ABO Blood Type Defined ARDS Endotype in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,726,654 | September 21, 2021 | August 31, 2026 | REILLY, JOHN PATRICK | reporter.nih.gov |
| Enhancing Innate and Adaptive Immunity to Improve Sepsis Survival | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,718,598 | May 1, 2018 | April 30, 2028 | HOTCHKISS, RICHARD SAMUEL | reporter.nih.gov |
| Lcn10 in Sepsis-Induced Vascular Leakage and Heart Failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,711,450 | December 1, 2021 | November 30, 2026 | FAN, GUO-CHANG | reporter.nih.gov |
| Negative regulators of endothelial regeneration in aging lungs and ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,661,375 | June 1, 2022 | March 31, 2026 | ZHAO, YOU-YANG | reporter.nih.gov |
| Sepsis Characterization in Kilimanjaro | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,660,507 | September 23, 2020 | August 31, 2025 | RUBACH, MATTHEW P | reporter.nih.gov |
| Tie2-driven vascular control in critical illness | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $2,655,728 | January 16, 2018 | December 31, 2025 | PARIKH, SAMIR M | reporter.nih.gov |
| A randomized clinical trial of early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,649,150 | September 18, 2020 | June 30, 2025 | HEYSELL, SCOTT K | reporter.nih.gov |
| Enhancement of Brain Dysfunction in Sepsis Survivors by Alzheimer’s Disease Neuropathology | NIH | National Institute on Aging | 2022 to 2025 | $2,646,143 | January 15, 2022 | December 31, 2026 | SINGER, BENJAMIN HERSCHEL | reporter.nih.gov |
| Training in Trauma and Sepsis Research | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,643,849 | July 1, 1994 | June 30, 2029 | BILLIAR, TIMOTHY R | reporter.nih.gov |
| Finding Appropriate Subtypes in a Trial of Balanced versus nOrmaL Saline FlUid in Sepsis | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,612,604 | September 20, 2022 | July 31, 2027 | YEHYA, NADIR | reporter.nih.gov |
| Innate Immune Clearance of Host-Adapted Pulmonary Pathogens | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,586,182 | January 11, 2017 | November 30, 2024 | PRINCE, ALICE S | reporter.nih.gov |
| TRPV1-dependent neuro-immune modulation and regulation of endogenous acyl-dopamines in sepsis and acute inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,579,514 | June 3, 2022 | May 31, 2027 | HELLMAN, JUDITH | reporter.nih.gov |
| Precision Medicine Approach to Glucocortisteroids in Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,573,427 | August 2, 2021 | June 30, 2026 | YENDE, SACHIN | reporter.nih.gov |
| Innate control of the inflammatory process during fungal infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,567,886 | March 1, 2016 | May 31, 2027 | ZANONI, IVAN | reporter.nih.gov |
| Neuroinflammation Maladapts Cardio Respiratory Circuits and Patterns | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,553,585 | September 1, 2022 | May 31, 2027 | JACONO, FRANK JOSEPH | reporter.nih.gov |
| Use of Time Series Biomarker and Clinical Data to Construct a Time Trajectory Host Response Map | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $2,544,352 | June 1, 2023 | May 31, 2025 | REDDY, BOBBY | reporter.nih.gov |
| Complement C5 inhibition as sepsis therapy | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,533,664 | February 9, 2022 | January 31, 2027 | LUPU, FLOREA | reporter.nih.gov |
| Host Immunity in Sepsis-Induced Systemic Infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,506,165 | May 1, 2021 | April 30, 2027 | JEYASEELAN, SAMITHAMBY | reporter.nih.gov |
| A Randomized Phase 2A Clinical Trial Pioneering the Utility of an eNAMPT-Reducing Therapy in ARDS/VILI: the PUERTA Trial | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $2,457,594 | June 1, 2019 | August 31, 2025 | GARCIA, JOE G. N. | reporter.nih.gov |
| Purinergic Regulation of Veinous Endothelial Permeability | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,433,353 | February 18, 2018 | May 31, 2027 | ISAKSON, BRANT E | reporter.nih.gov |
| Contact Activation and Infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,422,554 | September 23, 2020 | August 31, 2025 | MCCARTY, OWEN J | reporter.nih.gov |
| Understanding IL-27 as a negative regulator of protective immunity during neonatal sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,380,935 | June 1, 2021 | May 31, 2027 | ROBINSON, CORY MICHAEL | reporter.nih.gov |
| Sepsis online: learning while doing to understand biology and treatment | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,376,274 | August 2, 2016 | May 31, 2027 | SEYMOUR, CHRISTOPHER W. | reporter.nih.gov |
| Telehealth-Enhanced Patient-Oriented Recovery Trajectory After Intensive Care | NIH | National Institute on Aging | 2023 to 2025 | $2,359,166 | June 15, 2023 | May 31, 2028 | BOEHM, LEANNE M | reporter.nih.gov |
| Resubmission: Elucidating Pediatric Sepsis by Defining Comprehensive Signatures for Diagnosis and Outcome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,350,638 | September 1, 2022 | August 31, 2027 | MAHAJAN, PRASHANT | reporter.nih.gov |
| Targeting immune inhibitory molecule SUSD2 to reverse immunosuppression | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,341,818 | June 17, 2021 | May 31, 2026 | WEN, HAITAO | reporter.nih.gov |
| Reducing Variation in Sepsis Outcomes | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,335,522 | April 1, 2022 | March 31, 2027 | LINNANDER, ERIKA | reporter.nih.gov |
| Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,334,792 | July 1, 2019 | June 30, 2025 | YEHYA, NADIR | reporter.nih.gov |
| Combined Biomarker and EMR Data for Heterogeneous Treatment Effects and Surrogate Endpoints in Sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $2,323,248 | June 1, 2023 | May 31, 2025 | REDDY, BOBBY | reporter.nih.gov |
| PediatRic sEpsiS induCed MODS: Relationship of Immune-phenotypes and antiBiotic Exposures (PRESCRIBE) study | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,321,738 | June 19, 2023 | May 31, 2028 | DOWNES, KEVIN JAMES | reporter.nih.gov |
| Identifying pre-sepsis opportunities for early, targeted intervention | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,318,082 | August 1, 2018 | July 31, 2028 | LIU, VINCENT | reporter.nih.gov |
| Randomized Trial of non-Surgical Therapy and Oral Hygiene Instruction to Reduce Risk of Infective Endocarditis | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $2,308,812 | February 14, 2023 | January 31, 2028 | LOCKHART, PETER B | reporter.nih.gov |
| VENOUS: A translational study of enterococcal bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,305,203 | June 17, 2020 | May 31, 2026 | ARIAS, CESAR AUGUSTO | reporter.nih.gov |
| Amplification Mechanisms of Lung Endothelial Inflammation During Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,286,853 | January 15, 2021 | December 31, 2025 | REHMAN, JALEES | reporter.nih.gov |
| Training Innate Immunity: A new approach to the treatment of Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,271,692 | April 1, 2016 | May 31, 2026 | WILLIAMS, DAVID L. | reporter.nih.gov |
| Haptoglobin 2 variant and endothelial glycocalyx shedding in sepsis-induced ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,262,811 | September 1, 2021 | July 31, 2025 | WARE, LORRAINE B | reporter.nih.gov |
| GasderminD regulation of Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,261,470 | August 5, 2022 | June 30, 2027 | SARKAR, ANASUYA | reporter.nih.gov |
| GeneRAlizable Sepsis Phenotyping (GRASP) using Electronic Health Records and Continuous Monitoring Sensors | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,244,171 | August 1, 2021 | November 30, 2026 | NEMATI, SHAMIM | reporter.nih.gov |
| Control of septic inflammation and lung microvascular endothelial barrier by cell junction signaling nexus | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,241,297 | June 1, 2021 | May 31, 2026 | BIRUKOVA, ANNA | reporter.nih.gov |
| Adjuvant heat treatment for catheter salvage in central line associated bloodstream infection (HEATSAVE) | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,222,716 | May 10, 2022 | April 30, 2027 | VANEPPS, J SCOTT | reporter.nih.gov |
| Sepsis and the Systemic Cytokine Storm in Aging and Alzheimer Disease Models | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,218,350 | August 15, 2022 | July 30, 2025 | EFRON, PHILIP A | reporter.nih.gov |
| Surgical Studies of Gut Permeability | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,215,923 | August 25, 2004 | June 30, 2025 | WANG, JIAN-YING | reporter.nih.gov |
| Identifying patient subgroups and processes of care that cause outcome differences following ICU vs. ward triage among patients with acute respiratory failure and sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,204,852 | September 1, 2023 | June 30, 2027 | ANESI, GEORGE L | reporter.nih.gov |
| ISGylation regulates lung endothelial inflammation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,180,291 | April 20, 2021 | March 31, 2026 | ZHAO, YUTONG | reporter.nih.gov |
| ENdotypes in Children with Severe Acute Respiratory Distress SyNdrome: ImpAct on REsponse to Treatment (ENSNARE) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,178,644 | January 1, 2020 | November 30, 2025 | DAHMER, MARY K | reporter.nih.gov |
| Injectable Hydrogel Depots for Self-replicating mRNA Vaccine Delivery | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,169,016 | July 12, 2022 | June 30, 2027 | BRYERS, JAMES D. | reporter.nih.gov |
| Improving Sepsis Care with Deep RNA Sequencing Data | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,168,166 | September 1, 2021 | December 31, 2026 | MONAGHAN, SEAN FARRELL | reporter.nih.gov |
| The µSiM-hNVU - a human BBB platform for the study of brain injury mechanisms during systemic infection | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $2,162,325 | September 3, 2020 | August 31, 2025 | MCGRATH, JAMES L | reporter.nih.gov |
| Discovery and Characterization of Novel Sepsis Proteome Biomarkers | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,161,040 | September 10, 2021 | August 31, 2025 | LUPU, FLOREA | reporter.nih.gov |
| Informing best practices for evaluation and treatment of myocardial injury during sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,156,394 | September 1, 2023 | June 30, 2027 | WALKEY, ALLAN J. | reporter.nih.gov |
| Improvement of Organ Function after Severe Hypovolemia | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,155,286 | February 1, 2004 | December 31, 2026 | WANG, PING | reporter.nih.gov |
| Novel bi-specific immunoprophylactics against multi-drug resistant Gram-negativebacterial infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $2,153,664 | March 22, 2019 | April 30, 2024 | PERLIN, DAVID S | reporter.nih.gov |
| Pathological Myeloid Activation After Sepsis and Trauma | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,151,320 | June 1, 2021 | March 31, 2027 | EFRON, PHILIP A | reporter.nih.gov |
| Bacterial polyphosphates in sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,148,500 | February 22, 2021 | January 31, 2026 | BOSMANN, MARKUS | reporter.nih.gov |
| Neutrophil A2A receptors in sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,134,458 | September 15, 2021 | June 30, 2025 | HASKO, GEORGE | reporter.nih.gov |
| APOL1 associated disease spectrum | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,127,345 | December 21, 2015 | July 31, 2026 | SUSZTAK, KATALIN | reporter.nih.gov |
| Endotoxin preconditioning as a model to uncover protective pathways in sepsis-induced renal injury | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,116,770 | August 25, 2016 | May 31, 2027 | DAGHER, PIERRE C | reporter.nih.gov |
| Solving Sepsis: Early Identification and Prompt Management Using Machine Learning | NIH | National Institute of General Medical Sciences | 2022 to 2024 | $2,114,202 | June 1, 2022 | April 30, 2025 | PATEL, MANESH R | reporter.nih.gov |
| PAD2 and CitH3 in Pathogenesis of Sepsis-induced ALI | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,107,087 | September 1, 2021 | August 31, 2025 | LI, YONGQING | reporter.nih.gov |
| Vascular mechanisms of sepsis-induced cognitive dysfunction | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,105,189 | March 15, 2023 | February 29, 2028 | HERSON, PACO S | reporter.nih.gov |
| GBPs in inflammasome activation and host defense to infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,093,750 | September 19, 2014 | May 31, 2030 | MACMICKING, JOHN DAVID | reporter.nih.gov |
| Extracellular miRNAs, innate immunity, and critical illness | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,091,584 | May 1, 2021 | February 28, 2027 | CHAO, WEI | reporter.nih.gov |
| Red blood cell ATP export and transfusion in sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,086,031 | March 5, 2023 | December 31, 2026 | MCMAHON, TIMOTHY J | reporter.nih.gov |
| Polymeric nanoassemblies for precise tuning of immune responses | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,082,892 | July 1, 2021 | April 30, 2027 | PEARSON, RYAN MATTHEW | reporter.nih.gov |
| MAM Proteins in Lung Vascular Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,070,740 | May 1, 2023 | April 30, 2027 | FAZAL, FABEHA | reporter.nih.gov |
| Transcription Factor Elf2 Signals Resolution of Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,068,307 | March 15, 2021 | February 28, 2026 | TIRUPPATHI, CHINNASWAMY | reporter.nih.gov |
| Reduction of bloodstream infections from oral organisms in pediatric stem cell transplant: a randomized multicenter double-blind placebo-controlled study evaluating twice daily oral xylitol | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,064,644 | September 1, 2022 | August 31, 2027 | DANDOY, CHRISTOPHER EUGENE | reporter.nih.gov |
| Point-of-Care Microfluidic Biochip for Biomarkers Monitoring for Contributing in Early Sepsis Diagnosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,054,490 | August 5, 2021 | July 31, 2025 | BASHIR, RASHID | reporter.nih.gov |
| Structural and mechanistic elucidation of non-canonical inflammasome signaling | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,037,700 | March 17, 2021 | February 28, 2026 | RUAN, JIANBIN | reporter.nih.gov |
| Deep-CDS: Deep Learning Semantic Data Lake for Clinical Decision Support | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,028,267 | September 10, 2022 | August 31, 2025 | KABUKA, MANSUR R. | reporter.nih.gov |
| An automated culture-free system for the identification of bloodstream infections direct from blood | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $2,027,841 | July 8, 2024 | June 30, 2027 | SINGER, ALON | reporter.nih.gov |
| Identification and Validation of Biological Sub-phenotypes of Sepsis-induced Acute Kidney Injury: A Precision Medicine Approach to Improve Clinical Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,006,521 | August 1, 2022 | July 31, 2027 | BHATRAJU, PAVAN KUMAR | reporter.nih.gov |
| A Culture-Free Platform for Rapid Fungal Pathogen Identification | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $2,000,000 | August 1, 2014 | March 31, 2024 | SINGER, ALON | reporter.nih.gov |
| Development of WecA-targeting immune potentiators to treat carbapenem-resistant Enterobacteriaceae (CRE) infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $2,000,000 | August 1, 2019 | July 31, 2024 | ROEMER, TERRY | reporter.nih.gov |
| Using Clinical Treatment Data in a Machine Learning Approach for Sepsis Detection | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 | $1,999,554 | June 15, 2018 | June 15, 2022 | HOFFMAN, JANA | reporter.nih.gov |
| Targeting integrin outside-in signaling for treating sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,993,937 | September 1, 2018 | May 31, 2025 | SKIDGEL, RANDAL A | reporter.nih.gov |
| Clinical factors in aminoglycoside-induced ototoxicity | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2023 | $1,992,532 | July 1, 2019 | June 30, 2025 | STEYGER, PETER STEPHEN | reporter.nih.gov |
| Translational Metabolomics in Critical Care | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,981,512 | April 1, 2020 | January 31, 2030 | STRINGER, KATHLEEN A | reporter.nih.gov |
| Adaptive alterations of lipids in mitis group streptococci | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,979,502 | September 23, 2020 | August 31, 2025 | PALMER, KELLI LEA | reporter.nih.gov |
| Rapid Low Cost Phenotypic Antibiotic Susceptibility Testing | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,975,326 | February 7, 2017 | March 31, 2023 | RHODES, PAUL | reporter.nih.gov |
| Lung Macrophage Memory Development and Responses in Secondary Pneumonia and Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $1,972,366 | August 27, 2021 | July 31, 2026 | MISHRA, BIBHUTI BHUSAN | reporter.nih.gov |
| Immunological Endotyping of Chronic Critical Illness after Severe Trauma or Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,972,081 | August 15, 2021 | December 31, 2026 | BRAKENRIDGE, SCOTT CHARLES | reporter.nih.gov |
| Clinical Impact of the Cefazolin Inoculum Effect | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,970,877 | June 1, 2025 | May 31, 2028 | ARIAS, CESAR AUGUSTO | reporter.nih.gov |
| Pathobiology of MRSA-induced Endothelial Permeability and Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,963,994 | December 20, 2022 | November 30, 2026 | DUDEK, STEVEN M | reporter.nih.gov |
| Immuno-metabolic dysfunction in alcohol with sepsis | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $1,961,505 | September 20, 2021 | July 31, 2027 | VACHHARAJANI, VIDULA | reporter.nih.gov |
| The Role and Mechanisms of Lipid and Lipoprotein Dysregulation in Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,960,279 | April 1, 2020 | March 31, 2026 | GUIRGIS, FAHEEM W | reporter.nih.gov |
| Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,958,663 | August 15, 2018 | March 31, 2027 | LIM, YOW-PIN | reporter.nih.gov |
| Precision Medicine in Sepsis with Critical Illness | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,953,750 | August 1, 2021 | June 30, 2027 | SINHA, PRATIK | reporter.nih.gov |
| Infection-driven mechanisms associated with Alzheimer's disease pathology | NIH | National Institute on Aging | 2021 | $1,952,526 | May 15, 2021 | April 30, 2024 | MORALES, RODRIGO | reporter.nih.gov |
| Machine Learning and Multiomics for Predictive Models and Biomarker Discovery in Preterm Infants. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,951,076 | September 1, 2023 | August 31, 2028 | PAMMI, MOHAN | reporter.nih.gov |
| CD4 T cell dysfunction and reprogramming during sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,937,083 | May 1, 2021 | July 31, 2026 | GRIFFITH, THOMAS S | reporter.nih.gov |
| Macrophage immunometabolism controls septic shock | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,917,350 | June 22, 2023 | May 31, 2028 | ZANONI, IVAN | reporter.nih.gov |
| HDAC6 regulation of myeloid cell responses in sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,912,500 | September 17, 2021 | August 31, 2027 | FU, JIAN | reporter.nih.gov |
| IRGM proteins as regulators of inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,905,016 | February 7, 2020 | January 31, 2026 | TAYLOR, GREGORY A | reporter.nih.gov |
| HUMAN GENETIC VARIATION REGULATING SALMONELLA HOST-PATHOGEN INTERACTIONS AND DISEASE SUSCEPTIBILITY | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,901,258 | August 1, 2015 | November 30, 2025 | KO, DENNIS CHUN-YONE | reporter.nih.gov |
| Relative adrenal insufficiency as a risk factor and an endotype for sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,893,366 | May 1, 2021 | April 30, 2027 | LI, XIANG-AN | reporter.nih.gov |
| The impact of clinical interventions for sepsis in routine care and among detailed patient subgroups: A novel approach for causal effect estimation in electronic health record data | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,888,800 | August 18, 2022 | July 31, 2027 | GELDSETZER, PASCAL | reporter.nih.gov |
| C3-Dependent Intracellular Killing in Innate Immunity and Bacterial Pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,883,183 | March 5, 2019 | February 29, 2024 | RAFFATELLU, MANUELA | reporter.nih.gov |
| Neural mechanisms of age-related weakness | NIH | National Institute on Aging | 2023 to 2025 | $1,883,010 | August 15, 2023 | June 30, 2028 | CLARK, BRIAN C | reporter.nih.gov |
| Endothelial glycocalyx shedding in septic injury | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,869,047 | December 1, 2021 | November 30, 2026 | YUAN, SARAH Y | reporter.nih.gov |
| Regulation of neonatal inflammation by myeloid-derived suppressor cells | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,864,330 | April 15, 2020 | December 31, 2025 | NEFEDOVA, YULIA | reporter.nih.gov |
| Sepsis-Associated Immune Suppression and F-box Proteins | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,846,609 | September 30, 2009 | May 31, 2026 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| Inflammation Phenotypes in Pediatric Sepsis Induced Multiple Organ Failure Renewal | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,842,526 | March 1, 2014 | June 30, 2028 | CARCILLO, JOSEPH A | reporter.nih.gov |
| GPR68 as a novel modulator of septic lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,838,568 | August 1, 2023 | July 31, 2027 | BIRUKOVA, ANNA | reporter.nih.gov |
| Targeting Myofiber NAD(P)H Oxidases in Sepsis-Induced Myopathy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $1,829,773 | September 5, 2025 | August 31, 2028 | LAITANO, ORLANDO | reporter.nih.gov |
| Harnessing Fasting Metabolism to Improve Survival in Bacterial Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,829,765 | September 1, 2020 | August 31, 2025 | HUEN, SARAH | reporter.nih.gov |
| Phenotypically amplified assay for rapid, automated determination of beta-lactam susceptibility | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $1,795,199 | August 1, 2025 | July 31, 2029 | WHITE, IAN M | reporter.nih.gov |
| Calcium homeostasis and cellular fitness in sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,785,300 | September 1, 2022 | June 30, 2027 | ROSENGART, MATTHEW RANDALL | reporter.nih.gov |
| Molecular regulation of immunoproteasome assembly in inflammatory diseases | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,784,247 | July 1, 2023 | June 30, 2027 | ZHAO, JING | reporter.nih.gov |
| Mitigating Acute Lung Injury by Cell-specific Targeting of MTOR | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,768,287 | June 15, 2020 | May 31, 2025 | RAHMAN, ARSHAD | reporter.nih.gov |
| The Impact of Chronic Alcohol Abuse on the Pathophysiology of Sepsis | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $1,757,250 | August 1, 2014 | July 31, 2029 | COOPERSMITH, CRAIG M | reporter.nih.gov |
| Therapeutic Use of High Molecular Weight Hyaluronic Acid in Acute Lung Injury Following Severe Bacterial Pneumonia or Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,737,261 | May 1, 2020 | August 31, 2023 | LEE, JAE WOO | reporter.nih.gov |
| Mechanisms of organ dysfunction and recovery in the Acetaminophen and Ascorbate Trial in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,733,953 | June 15, 2022 | May 31, 2027 | WARE, LORRAINE B | reporter.nih.gov |
| A multimodal delivery and treatment approach for Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,731,773 | April 5, 2020 | March 31, 2025 | DEAN, DAVID A | reporter.nih.gov |
| Candida mediated protection against polymicrobial sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,727,496 | April 22, 2019 | July 31, 2025 | STEELE, CHAD | reporter.nih.gov |
| Control of lung permeability by oxidized phospholipids | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,723,566 | June 1, 2004 | May 31, 2025 | BIRUKOV, KONSTANTIN | reporter.nih.gov |
| Platelet- mast cell interactions as determinants of the vascular pathology in septic shock. | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,719,290 | September 22, 2021 | August 31, 2025 | ABRAHAM, SOMAN N | reporter.nih.gov |
| Novel mechanisms of endothelial Injury in the pathogenesis of ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,703,458 | May 1, 2020 | April 30, 2025 | ZHAO, YOU-YANG | reporter.nih.gov |
| Validation and early development of a blood-based rapid diagnostic test for sepsis endotypes | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $1,701,838 | August 15, 2021 | July 31, 2023 | SWEENEY, TIMOTHY E | reporter.nih.gov |
| Macrophage mitochodrial reprogramming and innate immune memory | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,699,805 | February 13, 2020 | January 31, 2026 | SHERWOOD, EDWARD R | reporter.nih.gov |
| Functional Significance of Ferritin Light Chain in Sepsis-associated Kidney Injury | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,688,641 | January 1, 2021 | December 31, 2026 | BOLISETTY, SUBHASHINI | reporter.nih.gov |
| Two novel threonine phosphorylations of STAT2 impact inflammatory responses to bacterial infection. | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,687,938 | August 7, 2020 | July 31, 2024 | STARK, GEORGE ROBERT | reporter.nih.gov |
| Depleting Circulating Galectin-3 with Therapeutic Apheresis: A NovelTreatment for Sepsis/AKI | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $1,681,971 | September 1, 2018 | May 31, 2025 | ELIAZ, ISAAC | reporter.nih.gov |
| Understand and Detect Sepsis: Pathogen Isolation, Biochemistry Assay, and Optofluidic Sensing | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,675,883 | August 1, 2021 | July 31, 2027 | DU, KE | reporter.nih.gov |
| Mechanisms of Dysregulated Innate Immune Responses to Lethal Infections | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,675,000 | September 1, 2022 | August 31, 2027 | WANG, HAICHAO | reporter.nih.gov |
| The Gut as a Target to Improve Outcomes in Sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,669,641 | February 1, 2023 | November 30, 2027 | COOPERSMITH, CRAIG M | reporter.nih.gov |
| Role of adipose tissue inflammaging and metabolic dysfunction during sepsis | NIH | National Institute on Aging | 2023 to 2025 | $1,651,115 | December 1, 2022 | November 30, 2027 | CAMELL, CHRISTINA | reporter.nih.gov |
| Novel Role of Lactate for Cardiovascular Dysfunction in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,645,677 | July 1, 2020 | April 30, 2026 | LI, CHUANFU | reporter.nih.gov |
| Role of heme and PGP matrikines in lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,641,507 | September 1, 2020 | July 31, 2025 | PATEL, RAKESH P. | reporter.nih.gov |
| Genetic analysis of pleiotropic drug resistance | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,634,406 | August 1, 1993 | February 28, 2026 | MOYE-ROWLEY, W SCOTT | reporter.nih.gov |
| Development of Synthetic High-Density Lipoproteins for Treatment of Sepsis | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $1,632,248 | February 15, 2022 | October 31, 2024 | LIPKA, ELKE | reporter.nih.gov |
| Roles of m6A mRNA Methylation in Innate Immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,620,000 | September 22, 2020 | August 31, 2025 | LI, YAN CHUN | reporter.nih.gov |
| Senolytics To slOw Progression of Sepsis (STOP-Sepsis) trial | NIH | National Institute on Aging | 2022 to 2024 | $1,615,531 | July 15, 2022 | June 30, 2025 | PUSKARICH, MICHAEL A. | reporter.nih.gov |
| Modulation of innate immune exhaustion during sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,615,091 | February 13, 2023 | January 31, 2028 | LI, LIWU | reporter.nih.gov |
| Fungal-bacterial dynamics driving dysregulated host responses and lethal synergism | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,608,527 | July 15, 2024 | June 30, 2029 | PETERS, BRIAN M | reporter.nih.gov |
| The role of antiviral programs in bacterial sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,604,064 | September 23, 2020 | August 31, 2025 | HATO, TAKASHI | reporter.nih.gov |
| Large-scale Implementation of Community Co-led Maternal Sepsis Care Practices to Reduce Morbidity and Mortality from Maternal Infection | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $1,575,463 | September 30, 2021 | August 31, 2023 | BAUER, MELISSA | reporter.nih.gov |
| Screening for Resistant Enteric Bacteria to Personalize Infection Prevention Strategies in Neutropenic Patients | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,560,126 | July 6, 2020 | June 30, 2025 | SATLIN, MICHAEL JOSEPH | reporter.nih.gov |
| Memory T Cell Cosigning Pathways in Sepsis-Induced Immune Dysregulation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,560,000 | July 15, 2015 | December 31, 2024 | FORD, MANDY L | reporter.nih.gov |
| Sepsis Early Prediction and Subphenotype Illumination Study (SEPSIS) | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,555,000 | May 1, 2022 | February 28, 2027 | CHURPEK, MATTHEW MICHAEL | reporter.nih.gov |
| Targeting iron to improve outcomes in neonatal Escherichia coli sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,548,490 | February 5, 2020 | January 31, 2026 | BERMICK, JENNIFER | reporter.nih.gov |
| Simple and rapid POC detection for fungemia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,541,716 | January 16, 2020 | December 31, 2022 | ALLAND, DAVID | reporter.nih.gov |
| Cellular and molecular mechanisms controlling sepsis-induced immunoparalyses state | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,540,904 | February 1, 2020 | January 31, 2026 | BADOVINAC, VLADIMIR P | reporter.nih.gov |
| COVID-19 Healthcare Access and Sequelae Evaluation | NIH | National Institute of Nursing Research | 2021 to 2022 | $1,538,904 | July 23, 2019 | April 30, 2024 | KOWALKOWSKI, MARC | reporter.nih.gov |
| Simple and rapid POC detection for fungemia | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $1,529,430 | January 16, 2020 | December 31, 2025 | ALLAND, DAVID | reporter.nih.gov |
| Novel intrinsic endothelial stem cells responsible for lung endothelial regeneration and vascular repair in ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,518,266 | December 22, 2023 | November 30, 2027 | ZHAO, YOU-YANG | reporter.nih.gov |
| Targeting brain inflammation and neurocognitive dysfunction in sepsis | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,514,261 | May 1, 2019 | February 28, 2025 | CHAO, WEI | reporter.nih.gov |
| Fetal alcohol exposure: effects on immunity of the premature newborn | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2023 | $1,512,894 | August 20, 2019 | July 31, 2025 | GAUTHIER, THERESA WANZOR | reporter.nih.gov |
| The NICU Antibiotics and Outcomes (NANO) Trial | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,508,072 | September 13, 2019 | August 31, 2025 | MOROWITZ, MICHAEL | reporter.nih.gov |
| E3 Ligase-Mediated Immunosuppression in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,507,608 | February 1, 2010 | June 30, 2026 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| Corticosteroids to Reduce Inflammation in Severe Pancreatitis (CRISP) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,506,305 | December 15, 2021 | November 30, 2026 | DONNINO, MICHAEL WILLIAM | reporter.nih.gov |
| Sepsis Physiomarkers for Appropriate Risk Knowledge of monitored patients in the ICU (SPARK-ICU) | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,502,912 | September 10, 2021 | June 30, 2027 | KAMALESWARAN, RISHIKESAN | reporter.nih.gov |
| Determining the conserved molecular mechanisms contributing to inflammation during Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,496,724 | May 14, 2020 | April 30, 2026 | CARPENTER, SUSAN | reporter.nih.gov |
| Promoting algorithmic equity in in-hospital mortality prediction | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,496,371 | September 9, 2024 | May 31, 2029 | KOHN, RACHEL | reporter.nih.gov |
| Situation Awareness to Improve Infant Sepsis Recognition in the Presence of Clinical Uncertainty | NIH | National Library of Medicine | 2021 to 2024 | $1,496,255 | August 1, 2021 | April 30, 2026 | GRUNDMEIER, ROBERT W | reporter.nih.gov |
| Prevention of Neonatal Sepsis by Therapeutic Targeting of MDSCs | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,494,508 | April 1, 2022 | February 28, 2027 | LARSON, SHAWN DAVID | reporter.nih.gov |
| Mucosal Repair in Gut Surgical Disorders | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,484,427 | July 1, 2002 | May 31, 2025 | WANG, JIAN-YING | reporter.nih.gov |
| Novel coenzyme Q6 variant reveals non-immune determinants of survival during pneumococcal sepsis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,481,057 | August 26, 2024 | July 31, 2028 | MORLEY, SHARON CELESTE | reporter.nih.gov |
| ROCK, tight junctions and prematurity in the pathogenesis of necrotizing enterocolitis and neonatal sepsis. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,473,953 | April 1, 2023 | January 31, 2028 | HUNTER, CATHERINE JANE | reporter.nih.gov |
| Protective versus deleterious immune responses that impact vaccine efficacy against Staphylococcus aureus bloodstream infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,473,115 | March 12, 2020 | February 28, 2023 | AMAN, M JAVAD | reporter.nih.gov |
| The Sepsis ClinicAl Resource And Biorepository (SCARAB) Project | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,461,247 | January 1, 2022 | January 31, 2026 | BASTARACHE, JULIE A. | reporter.nih.gov |
| A "Culture" Shift: Integrated Bacterial Screening and Antibacterial Susceptibility Test on Microfluidic Digital Array for Bloodstream Infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,434,371 | January 23, 2018 | December 31, 2023 | WANG, TZA-HUEI JEFF | reporter.nih.gov |
| Inflammatory Organ Injury after Pneumonia-Derived Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,430,432 | July 1, 2024 | May 31, 2029 | JEYASEELAN, SAMITHAMBY | reporter.nih.gov |
| Integrated genotype-informed single-cell molecular antibacterial susceptibility testing platform for rapid and actionable diagnosis of bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,427,208 | February 1, 2024 | December 31, 2028 | WANG, TZA-HUEI JEFF | reporter.nih.gov |
| Surprising Efficacy of Discounted Antibiotics vs. MDR Gram-Negative Pathogens Occurring Through Innate Immune Sensitization | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,422,000 | August 1, 2020 | July 31, 2025 | NIZET, VICTOR | reporter.nih.gov |
| Pediatric Sepsis Biorepository and Clinical Database | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,420,824 | April 11, 2022 | March 31, 2027 | BALAMUTH, FRANCES B | reporter.nih.gov |
| Clinical Validation of a Point-of-Care Precision Medicine Endotyping Platform | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,400,000 | September 30, 2024 | August 31, 2027 | REDDY, BOBBY | reporter.nih.gov |
| Novel exosomal niches for alveolar stem cell-bassed repair of ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,397,980 | September 1, 2017 | April 30, 2027 | JI, HONG-LONG | reporter.nih.gov |
| Multiomic, mass spectrometry-based analysis of dried blood for deep phenotyping of sepsis | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,387,000 | April 1, 2022 | September 30, 2026 | FOSTER, MATTHEW WOLF | reporter.nih.gov |
| Fitness of gram-negative pathogens during bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,386,158 | August 5, 2019 | July 31, 2024 | MOBLEY, HARRY L. | reporter.nih.gov |
| The Role of Pericytes in the Vascular Dysfunction of Sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,381,815 | May 1, 2023 | March 31, 2028 | FAN, HONGKUAN | reporter.nih.gov |
| Therapeutic modulation of zinc for lung injury and mechanobiology | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,381,362 | April 1, 2019 | March 31, 2025 | BARON, REBECCA M | reporter.nih.gov |
| Hyperglycemia and increased severity to Staphylococcus aureus infections. | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,374,720 | July 1, 2024 | May 31, 2029 | SEREZANI, C. HENRIQUE | reporter.nih.gov |
| Salivary Diagnostics for Sepsis Screening in the Neonate | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $1,365,552 | August 9, 2019 | April 30, 2025 | MARON, JILL LAMANNA | reporter.nih.gov |
| Mitochondrial R-loop in sepsis-induced cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,362,731 | January 12, 2023 | December 31, 2027 | HUANG, WEI | reporter.nih.gov |
| Redox Trapping for Biospecimen Preservation and Innovation in Sepsis Care | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,361,825 | January 1, 2022 | December 31, 2026 | FURDUI, CRISTINA MARIA | reporter.nih.gov |
| Development of Targeted Antipseudomonal Bactericidal Prodrugs | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,357,558 | February 4, 2023 | January 31, 2028 | ALABI, CHRISTOPHER AKINLEYE | reporter.nih.gov |
| Enhanced Metadata Design, Architecture, and Learning (MeDAL) for Development of Generalizable Deep Learning-based Predictive Analytics from Electronic Health Records | NIH | National Library of Medicine | 2022 to 2025 | $1,343,000 | May 1, 2022 | July 31, 2026 | NEMATI, SHAMIM | reporter.nih.gov |
| Sepsis Physiomarkers for Appropriate Risk Knowledge of monitored patients in the ICU (SPARK-ICU) | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,338,983 | September 10, 2021 | January 31, 2024 | KAMALESWARAN, RISHIKESAN | reporter.nih.gov |
| Determinants of cardioprotection by circulating prohibitin-1 during sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,334,198 | April 11, 2023 | March 31, 2027 | ANDERSON, ETHAN JOHN | reporter.nih.gov |
| Integrated Host-Microbe Metagenomics for Sepsis Pathogen Surveillance, Subphenotyping and Outcome Prediction | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,324,867 | June 21, 2024 | April 30, 2029 | LANGELIER, CHARLES | reporter.nih.gov |
| Molecular mechanism of cardiac inflammation and dysfunction in Pseudomonas aeruginosa infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,319,211 | July 1, 2019 | June 30, 2025 | RAJARAM, MURUGESAN | reporter.nih.gov |
| Aerosolized Chemically Modified Tetracycline Nanoformulation for the Treatment of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,314,098 | March 1, 2025 | February 28, 2028 | KOLLISCH-SINGULE, MICHAELA CHRISTINA | reporter.nih.gov |
| Mechanisms of Tissue Immune Regulation in Sepsis and Local Infection | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,283,250 | July 1, 2019 | April 30, 2024 | NOWARSKI, RONI | reporter.nih.gov |
| Protective versus deleterious immune responses that impact vaccine efficacy against Staphylococcus aureus bloodstream infection | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $1,282,881 | March 12, 2020 | February 28, 2026 | AMAN, M JAVAD | reporter.nih.gov |
| Multidimensional and longitudinal immune profiling of sepsis in Uganda | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,278,790 | August 1, 2025 | July 31, 2029 | CUMMINGS, MATTHEW JOHN | reporter.nih.gov |
| Muscle and physical function recovery after acute critical illness | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,272,324 | September 18, 2023 | August 31, 2028 | DUPONT-VERSTEEGDEN, ESTHER E | reporter.nih.gov |
| Integration of Immunologic Phenotyping with Computational Approaches to Predict Clinical Trajectory in Septic Patients | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,270,338 | August 1, 2023 | May 31, 2028 | BONAVIA, ANTHONY S | reporter.nih.gov |
| Sex-related differences in cardiac mitochondrial response to inflammation | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,264,317 | December 22, 2022 | November 30, 2026 | WANG, MEIJING | reporter.nih.gov |
| AIVIS: Next Generation Vigilant Information Seeking Artificial Intelligence-based Clinical Decision Support for Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $1,257,723 | July 7, 2023 | June 30, 2025 | JOSEF, CHRISTOPHER | reporter.nih.gov |
| Role of GDF15 in the Regulation of Host Tolerance to Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,256,250 | January 1, 2019 | December 31, 2023 | MEDZHITOV, RUSLAN | reporter.nih.gov |
| Mechanisms of Novel Herbal Therapies for Sepsis. | NIH | National Center for Complementary & Integrative Health | 2021 to 2023 | $1,256,250 | September 1, 2010 | June 30, 2025 | WANG, HAICHAO | reporter.nih.gov |
| The role of purine biosynthesis and stringent response in persistent MRSA endovascular infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,252,387 | January 14, 2019 | December 31, 2024 | XIONG, YAN Q. | reporter.nih.gov |
| Infection-driven mechanisms associated with Alzheimer's disease pathology | NIH | National Institute on Aging | 2024 to 2025 | $1,246,017 | May 15, 2021 | April 30, 2027 | MORALES, RODRIGO | reporter.nih.gov |
| Mechanisms underlying regulation of intestinal epithelial homeostasis in sepsis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,220,704 | February 15, 2020 | November 15, 2022 | TAN, XIAO-DI | reporter.nih.gov |
| Achieving High Quality Outcomes for Patients with Acute Respiratory Distress Syndrome: Lessons Learned from Nurses in High Performing Hospitals | NIH | National Institute of Nursing Research | 2023 to 2025 | $1,218,750 | March 27, 2023 | February 28, 2027 | BROOKS CARTHON, JACQUELINE MARGO | reporter.nih.gov |
| Hematopoietic Stem Cell Dysfunction and Regeneration in Severe Infection | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,215,000 | April 1, 2019 | March 31, 2025 | MACNAMARA, KATHERINE C. | reporter.nih.gov |
| Identification of sub-phenotypes of severely ill burn patients and risk for secondary sepsis: SEPSISBURN | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,207,723 | September 15, 2023 | July 31, 2027 | LEGRAND, MATTHIEU | reporter.nih.gov |
| Immune Function in Sepsis: Role of Sirtuin | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,207,500 | May 1, 2023 | February 29, 2028 | VACHHARAJANI, VIDULA | reporter.nih.gov |
| Nanoparticle Targeting of Neutrophil Subpopulations in Inflammatory Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,198,434 | August 15, 2019 | June 30, 2024 | MALIK, ASRAR B. | reporter.nih.gov |
| Timely Response to In-Hospital Deterioration Through Design of Actionable Augmented Intelligence | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,197,553 | July 15, 2020 | June 30, 2025 | MADARAS-KELLY, KARL J. | reporter.nih.gov |
| Analyzing the long-term effects of DNA methylation meditated immunosuppression following sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,197,422 | September 10, 2023 | July 31, 2028 | WISLER, JON R | reporter.nih.gov |
| ER-phagy regulation of immune response: mechanisms and significance | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,196,456 | September 5, 2024 | May 31, 2029 | HU, GUOCHANG | reporter.nih.gov |
| Cell-free DNA epigenomics to track the dynamics of organ damage and immune exhaustion during sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,181,249 | September 1, 2021 | April 1, 2024 | CHAUDHURI, AADEL | reporter.nih.gov |
| Randomized Trial of non-Surgical Therapy and Oral Hygiene Instruction to Reduce Risk of Infective Endocarditis | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2024 | $1,179,698 | February 14, 2023 | February 2, 2024 | LOCKHART, PETER B | reporter.nih.gov |
| Targeting the host immune response during sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,175,755 | September 15, 2020 | June 30, 2025 | HU, GUOCHANG | reporter.nih.gov |
| Cell death proteins as inflammatory mediators in sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,173,750 | August 1, 2023 | May 31, 2028 | LYONS, JOHN DANIEL | reporter.nih.gov |
| Innate Immunity in Lung Infection-induced Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $1,170,976 | June 1, 2018 | May 31, 2025 | JEYASEELAN, SAMITHAMBY | reporter.nih.gov |
| Novel approaches to detect and treat sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,166,861 | August 1, 2022 | July 31, 2027 | CHEN, JUHONG | reporter.nih.gov |
| The MUltidimenSional phenotyping In Critical care (MUSIC) Consortium: A pathway to precision medicine at the bedside | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,162,536 | May 1, 2023 | April 30, 2029 | WARE, LORRAINE B | reporter.nih.gov |
| How Tetraspanins Regulate Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,160,000 | September 1, 2020 | June 30, 2026 | ZHANG, XIN A | reporter.nih.gov |
| Electrochemical Catheter for Prevention of Central Line-Associated Bloodstream Infection | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,159,808 | February 20, 2023 | January 31, 2027 | PATEL, ROBIN | reporter.nih.gov |
| CD11c as a novel target to improve neutrophil effector functions and sepsis outcome | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,157,817 | February 1, 2023 | December 31, 2026 | YUKI, KOICHI | reporter.nih.gov |
| Profiles and impact of venous congestion on organ function and patient outcomes in sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,155,000 | August 15, 2023 | May 31, 2028 | EHRMAN, ROBERT RUSSELL | reporter.nih.gov |
| Measuring and Learning from Care Variation in Sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,151,250 | September 1, 2023 | August 31, 2028 | PELTAN, ITHAN DANIEL | reporter.nih.gov |
| The Impact of the Bundled Payment for Care Improvement Advanced on Outcomes for Patients with Sepsis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,150,379 | December 25, 2022 | November 30, 2026 | RYAN, ANDREW M | reporter.nih.gov |
| Advancing Precision Medicine for ARDS and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2025 | $1,147,992 | April 1, 2025 | March 31, 2032 | CALFEE, CAROLYN | reporter.nih.gov |
| Colorado APS Clinical Center | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,144,687 | May 1, 2023 | April 30, 2029 | MOSS, MARC | reporter.nih.gov |
| Phenotyping ARDS, Pneumonia, and Sepsis over time to elucidate shared and distinct trajectories ofillness and recovery | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,144,421 | May 1, 2023 | April 30, 2029 | MEYER, NUALA JENNINGS | reporter.nih.gov |
| Integrated Detection and Classification of Sepsis via Tensor Methods Using EHR | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,143,909 | April 1, 2024 | March 31, 2029 | ZHANG, ANRU | reporter.nih.gov |
| Great Lakes Clinical Center of the Acute Respiratory Distress Syndrome, Pneumonia and Sepsis (APS) Consortium | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,140,945 | May 1, 2023 | April 30, 2029 | HYZY, ROBERT C | reporter.nih.gov |
| Novel Role of Lactate in Sepsis Impaired Immune Function | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,135,360 | December 12, 2023 | October 31, 2028 | LI, CHUANFU | reporter.nih.gov |
| The Intermountain West-Atlantic Center (InterACT) for the APS Phenotyping Consortium | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,133,343 | May 1, 2023 | April 30, 2029 | BROWN, SAMUEL MORRIS | reporter.nih.gov |
| Phosphatase and tensin homolog PTEN actions in polymicrobial sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,127,360 | July 15, 2014 | June 30, 2023 | SEREZANI, C. HENRIQUE | reporter.nih.gov |
| Microsystems to Decipher Leukocyte Decision-Making | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,126,887 | September 1, 2019 | June 30, 2025 | JONES, CAROLINE N. | reporter.nih.gov |
| Platelet Activating Factor and Epidermal Cytoxicity | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,125,000 | July 1, 1999 | November 30, 2024 | TRAVERS, JEFFREY B. | reporter.nih.gov |
| Molecular Phenotyping of ARDS, Pneumonia, and Sepsis using Latent Class Analysis and Metagenomic Sequencing | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,118,088 | May 1, 2023 | April 30, 2029 | CALFEE, CAROLYN | reporter.nih.gov |
| S100A9 and MDSC development in sepsis. | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,110,000 | April 1, 2019 | March 31, 2026 | ELGAZZAR, MOHAMED A. | reporter.nih.gov |
| Targeting professional APCs using Fasciola hepatica FABP to suppresses inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,106,359 | August 1, 2020 | July 31, 2025 | ESPINO, ANA M | reporter.nih.gov |
| Developing a Novel E3 Ligase based Anti-inflammatory for ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $1,102,297 | February 1, 2022 | January 31, 2025 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| The role of circadian clock proteins in innate and adaptive immunity | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,096,430 | September 26, 2022 | July 31, 2026 | ROSENGART, MATTHEW RANDALL | reporter.nih.gov |
| Sepsis from Bedside to Bench to Bedside | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $1,087,989 | April 1, 2018 | March 31, 2023 | ALDER, MATTHEW N | reporter.nih.gov |
| Glycocalyx repair in sepsis using liposomal carriers of preassembled glycocalyx | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,082,400 | August 5, 2019 | June 30, 2024 | GOLIGORSKY, MICHAEL S | reporter.nih.gov |
| Development of a Mobile Health Personalized Physiologic Analytics Tool for Pediatric Patients with Sepsis | NIH | Fogarty International Center | 2023 to 2025 | $1,079,973 | August 10, 2021 | April 30, 2026 | GARBERN, STEPHANIE CHOW | reporter.nih.gov |
| Bioactive immune-modulating nanodrug for sepsis treatment | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $1,064,026 | May 1, 2024 | February 28, 2029 | LUO, JUNTAO | reporter.nih.gov |
| Role of Toll-like Receptor 9 in Fibroblastic Reticular Cell-based Therapy for Intra-abdominal Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $1,053,634 | February 24, 2020 | January 31, 2026 | DENG, MEIHONG | reporter.nih.gov |
| Effects of Platelet Transfusions on Neonatal Chronic Lung Disease and Sepsis-Induced Mortality | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $1,042,475 | May 15, 2021 | April 30, 2026 | DAVENPORT, PATRICIA ELLEN | reporter.nih.gov |
| Effect of Mitochondrial Quality Control on Systemic Inflammation and Organ Dysfunction in Pediatric Sepsis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2024 | $1,037,234 | September 1, 2020 | June 30, 2026 | WEISS, SCOTT L | reporter.nih.gov |
| SnapCap: a device to decontaminate central venous catheters (CVC) with 5 snaps | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $1,036,191 | September 21, 2018 | August 31, 2023 | KHEIR, JOHN NAGI | reporter.nih.gov |
| Mesenchymal Stromal Cells, Autophagy, and the Host Response to Systemic Bacterial Infection | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,028,496 | April 1, 2020 | January 31, 2025 | PERRELLA, MARK A | reporter.nih.gov |
| Controlling bactermic pneumococcal pneumonia with synthetic dominant-negative competence peptides | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,023,618 | April 1, 2019 | March 31, 2024 | LAU, GEE W | reporter.nih.gov |
| Precision characterization of antimicrobial resistance gene dynamics in bloodstream infection risk after hematopoietic stem cell transplantation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,013,095 | September 10, 2021 | August 31, 2026 | ANDERMANN, TESSA | reporter.nih.gov |
| Identification of a Damaging Subset of Neutrophils that Arises in Septic Patients | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,008,024 | September 1, 2019 | June 30, 2024 | REICHNER, JONATHAN S | reporter.nih.gov |
| Role of STAT3 in sepsis-induced adipose tissue browning and the impact of obesity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $995,565 | September 25, 2017 | August 31, 2027 | KAPLAN, JENNIFER MELISSA | reporter.nih.gov |
| Understanding Interleukin-18 Mediated Susceptibility to Systemic Hyperinflammation | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $993,999 | April 1, 2021 | March 31, 2025 | CANNA, SCOTT WILLIAM | reporter.nih.gov |
| Collaborative Platform for Developing Sepsis Products by Leveraging Sepsis Endotypes Developed Using a Unified Biomarker-Clinical Dataset | NIH | National Institute of General Medical Sciences | 2021 | $989,522 | September 5, 2020 | July 31, 2022 | REDDY, BOBBY | reporter.nih.gov |
| Attenuation of Multiorgan Dysfunction after Shock in the Aged | NIH | National Institute on Aging | 2023 to 2025 | $988,764 | August 1, 2023 | April 30, 2028 | SCHMID-SCHOENBEIN, GEERT W. | reporter.nih.gov |
| Preclinical development of Novo29, a new antibiotic | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $977,463 | January 10, 2018 | March 31, 2023 | LING, LOSEE LUCY | reporter.nih.gov |
| Necroinflammatory Cell Death in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $974,700 | August 15, 2021 | July 31, 2026 | SCHENCK, EDWARD JAMES | reporter.nih.gov |
| Bloodstream infection detection directly on whole blood | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $969,449 | September 17, 2025 | August 31, 2028 | CELEDON, ALFREDO ANDRES | reporter.nih.gov |
| Role reversal of MAVS in bacterial sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $964,762 | August 15, 2018 | June 30, 2024 | BOSMANN, MARKUS | reporter.nih.gov |
| Safe and Effective Whole Blood ID/AST Device for Use in Neonatal ICU Settings | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $962,488 | May 1, 2015 | April 30, 2023 | GAU, VINCENT JEN-JR | reporter.nih.gov |
| EnCoRe MOMS: Engaging Communities to Reduce Morbidity from Maternal Sepsis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 | $957,978 | September 21, 2022 | September 20, 2023 | REDDY, UMA | reporter.nih.gov |
| Understanding pathology of sepsis-induced physical disability for future precision medicine | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $943,020 | August 1, 2023 | May 31, 2028 | MANKOWSKI, ROBERT T | reporter.nih.gov |
| Novel role of LSECs in hepatic immune and metabolic function during sepsis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $941,518 | April 15, 2024 | February 28, 2029 | WANG, XIAOHUI | reporter.nih.gov |
| A Randomized Clinical Trial of the Safety and FeasibiLity of Metformin as a Treatment for sepsis induced AKI (LiMiT AKI) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $941,280 | May 19, 2023 | April 30, 2027 | GOMEZ DANIES, HERNANDO | reporter.nih.gov |
| Metabolic and purinergic immune regulation | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $935,000 | April 1, 2020 | February 28, 2023 | JUNGER, WOLFGANG G | reporter.nih.gov |
| Mechanisms driving endothelial angiopoietin-2 expression and vascular dysfunction during pediatric sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $930,180 | September 10, 2021 | August 31, 2026 | RICHTER, ROBERT P | reporter.nih.gov |
| Pathogenesis of infection in pancreatitis: from sterile inflammation to sepsis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $924,056 | April 1, 2019 | December 31, 2022 | SINGH, VIJAY PREM | reporter.nih.gov |
| The molecular mechanism of Siglec-E in bacterial clearance | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $924,000 | June 13, 2024 | April 30, 2029 | CHEN, GUOYUN | reporter.nih.gov |
| Epigenetic Modulation in Septic Immunosuppression | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $921,732 | May 15, 2019 | March 31, 2024 | ZOU, CHUNBIN | reporter.nih.gov |
| Tie2-driven vascular control in critical illness | NIH | National Heart, Lung, and Blood Institute | 2021 | $921,078 | January 16, 2018 | December 31, 2021 | PARIKH, SAMIR M | reporter.nih.gov |
| The Syndemic of Sepsis, Multimorbidity, Aging, and Low Healthcare Access and Quality in the United States | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $920,841 | April 1, 2021 | March 31, 2027 | RUDD, KRISTINA ELIZABETH | reporter.nih.gov |
| Targeted nutritional approach to restore muscle health and physical activity after sepsis | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $914,821 | September 1, 2024 | August 31, 2028 | DEUTZ, NICOLAAS E | reporter.nih.gov |
| Digital High Resolution Melt and Machine Learning for Rapid and Specific Diagnosis in Neonatal Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $910,568 | May 1, 2018 | April 30, 2023 | FRALEY, STEPHANIE IRENE | reporter.nih.gov |
| Role of endothelial JAK/STAT signaling in the regulation of vascular leakage | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $906,525 | September 20, 2018 | July 31, 2023 | ADAM, ALEJANDRO PABLO | reporter.nih.gov |
| Solid-state nanopore detection of protein biomarkers for early sepsisdiagnosis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $899,936 | September 15, 2022 | March 31, 2027 | GUAN, XIYUN | reporter.nih.gov |
| Identification of Precision Sepsis Subphenotypes Using Vital Sign Trajectories | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $890,198 | September 15, 2021 | August 31, 2026 | BHAVANI, SIVASUBRAMANIUM | reporter.nih.gov |
| Leveraging implementation and behavioral science to reduce harmful overuse of diagnostic testing in critically ill children | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $889,655 | January 1, 2021 | June 30, 2026 | WOODS-HILL, CHARLOTTE Z | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $888,380 | August 18, 2021 | July 31, 2026 | SHEIN, STEVEN | reporter.nih.gov |
| Cell-based high-throughput chemical genetic screening for GSDMD inhibitors | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $885,000 | January 2, 2019 | December 31, 2023 | LUO, HONGBO R | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $878,240 | August 18, 2021 | July 31, 2026 | BERG, ROBERT ALLEN | reporter.nih.gov |
| Therapeutic and Metabolic Responses of Citrulline vs. Arginine Supplementation | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $871,044 | August 1, 2014 | June 30, 2025 | BURRIN, DOUGLAS G | reporter.nih.gov |
| An Innovative Immune Therapy with Antibiotics to Treat Deadly Excess Inflammation in Sepsis and ARDS Induced from Severe Bacterial Infection in Geriatric Patients | NIH | National Institute on Aging | 2021 to 2025 | $860,725 | September 30, 2021 | May 31, 2027 | ROUSSEL, EUGENE | reporter.nih.gov |
| Pediatric Recovery After Sepsis Treatment in the Pediatric Intensive Care Unit | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $859,700 | September 1, 2022 | August 31, 2026 | PERRY-EADDY, MALLORY A | reporter.nih.gov |
| Control of Type I Interferon Production in Response to Candida | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $859,490 | April 10, 2020 | July 31, 2030 | VYAS, JATIN M | reporter.nih.gov |
| Impact of Flagellin Variants and Receptors on the Progression and Outcome of Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $851,242 | August 1, 2019 | April 30, 2024 | MULVEY, MATTHEW A | reporter.nih.gov |
| Predisposition for Lung Injury in Sepsis Survival | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $847,800 | May 1, 2021 | April 30, 2026 | DENSTAEDT, SCOTT JOHN | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $845,805 | August 18, 2021 | July 31, 2026 | KHEMANI, ROBINDER | reporter.nih.gov |
| Metabolic and purinergic immune regulation | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $829,735 | April 1, 2020 | February 28, 2026 | JUNGER, WOLFGANG G | reporter.nih.gov |
| Improving Safety and Trustworthiness in Data-Driven Decision Learning for Sepsis | NIH | National Library of Medicine | 2025 | $828,904 | September 17, 2025 | August 31, 2027 | TANG, LU | reporter.nih.gov |
| Endothelial mechanisms of multiorgan dysfunction | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $819,583 | September 15, 2024 | August 31, 2029 | ADAM, ALEJANDRO PABLO | reporter.nih.gov |
| Characterizing a High-Reliability Implementation Program for Sepsis: Sepsis Tools AND Accurate Reporting of Outcome Differences (STANDARD) Study | NIH | National Heart, Lung, and Blood Institute | 2025 | $814,313 | August 1, 2025 | May 31, 2029 | MOHR, NICHOLAS M. | reporter.nih.gov |
| Improving sepsis care with AI-based clinical decision support | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $812,500 | July 15, 2024 | May 31, 2029 | WEISSMAN, GARY | reporter.nih.gov |
| Rapid Culture-Independent Detection of Sepsis Causing Microorganism Directly from Blood | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $809,789 | July 1, 2024 | May 31, 2029 | LIU, CHANG | reporter.nih.gov |
| Impact of polymicrobial interactions and within-host adaptation on CAUTI pathogenesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $809,427 | September 9, 2025 | June 30, 2030 | ARMBRUSTER, CHELSIE ELIZABETH | reporter.nih.gov |
| Lung-Brain Axis as a Mediator of Delirium | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $809,080 | August 1, 2021 | June 30, 2026 | HIPPENSTEEL, JOSEPH ALAN | reporter.nih.gov |
| Cell-free DNA epigenomics to track the dynamics of organ damage and immune exhaustion during sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $807,001 | September 1, 2021 | June 30, 2026 | CHAUDHURI, AADEL | reporter.nih.gov |
| Altered innate leukocyte programming dynamics in sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $805,000 | November 15, 2017 | October 31, 2023 | LI, LIWU | reporter.nih.gov |
| Antimicrobial mechanisms of Specialized Proresolving Medicators | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $805,000 | June 1, 2018 | May 31, 2024 | YIN, KINGSLEY E | reporter.nih.gov |
| Translational approaches to unravel organ-specific microvascular endothelial responses in sepsis. | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $802,500 | July 1, 2024 | April 30, 2029 | ATREYA, MIHIR R | reporter.nih.gov |
| 2/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $801,778 | September 16, 2020 | August 31, 2025 | LEISENRING, WENDY M | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $800,895 | August 18, 2021 | July 31, 2026 | AKCAN ARIKAN, AYSE | reporter.nih.gov |
| IND-enabling studies of the potent LpxC inhibitor LPC-233 as a novel antibiotic against Gram-negative pathogens | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $794,342 | April 16, 2020 | September 30, 2022 | DUNCAN, CLAYTON | reporter.nih.gov |
| VENOUS: A translational study of enterococcal bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $785,566 | June 17, 2020 | May 31, 2022 | ARIAS, CESAR AUGUSTO | reporter.nih.gov |
| Antibiotic disruption of the gut microbiome and immune response in neonatal late-onset sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $785,098 | August 24, 2021 | July 31, 2026 | SCHWARTZ, DREW JOEL | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $784,685 | August 18, 2021 | July 31, 2026 | CARCILLO, JOSEPH A | reporter.nih.gov |
| Pragmatic trial of midodrine as a vasopressor-sparing agent in septic shock | NIH | National Heart, Lung, and Blood Institute | 2025 | $783,661 | September 5, 2025 | August 31, 2026 | GAJIC, OGNJEN | reporter.nih.gov |
| Obesity-mediated protection in sepsis | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $782,337 | July 1, 2024 | April 30, 2029 | STARR, MARLENE ELENA | reporter.nih.gov |
| Glucocorticoids in short- and long-term critical illness outcomes | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $780,000 | July 1, 2024 | April 30, 2029 | SPENCER-SEGAL, JOANNA LOUISE | reporter.nih.gov |
| Impact of early gut microbiome features on risk of neutropenic fever and bloodstream infection in hematologic malignancy | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $779,760 | February 13, 2020 | January 31, 2026 | ZIEGLER, MATTHEW | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $778,440 | August 18, 2021 | July 31, 2026 | MOURANI, PETER MICHAEL | reporter.nih.gov |
| The Impact of Fluid Resuscitation on Glycocalyx Degradation in Septic Shock | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $777,496 | September 1, 2019 | May 31, 2025 | SHAPIRO, NATHAN I | reporter.nih.gov |
| Redox control over metabolism and mitochondrial bioenergetics directs the course of acute inflammation and sepsis. | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $775,044 | May 1, 2018 | October 31, 2024 | MCCALL, CHARLES EMORY | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $773,450 | August 18, 2021 | July 31, 2026 | STEINER, MARIE E | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $768,460 | August 18, 2021 | July 31, 2026 | HALL, MARK W | reporter.nih.gov |
| Role of MMP3 in cardiac microvascular barrier dysfunction and heart failure during sepsis | NIH | National Heart, Lung, and Blood Institute | 2025 | $762,950 | September 15, 2025 | June 30, 2029 | WU, RONGXUE | reporter.nih.gov |
| Modifiable Determinants of Mortality in Neonatal Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $762,500 | June 1, 2018 | May 31, 2024 | WYNN, JAMES LAWRENCE | reporter.nih.gov |
| Targeting Siglec-9/E for therapy of sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $760,000 | June 8, 2018 | May 31, 2024 | CHEN, GUOYUN | reporter.nih.gov |
| Integrated Multi-omics of Melioidosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $758,287 | August 23, 2018 | July 31, 2023 | WEST, TIMOTHY EOIN | reporter.nih.gov |
| Microvascular Thrombosis in systemic inflammation | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $755,736 | September 25, 2014 | June 30, 2024 | CRUZ, MIGUEL ANGEL | reporter.nih.gov |
| Phenotype prediction and therapeutic targets in high-risk pediatric sepsis-associated MODS | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $755,722 | December 15, 2023 | November 30, 2028 | SANCHEZ-PINTO, LAZARO NELSON | reporter.nih.gov |
| Dysfunctional Renin-Angiotensin System in Septic Shock | NIH | National Heart, Lung, and Blood Institute | 2025 | $753,208 | August 15, 2025 | May 31, 2030 | CHAPPELL, MARK C | reporter.nih.gov |
| SMART-SEPSIS: Sequential MAchine learning for individualized Response to early Treatment in lung SEPSIS | NIH | National Heart, Lung, and Blood Institute | 2025 | $750,561 | August 21, 2025 | May 31, 2029 | PIRRACCHIO, ROMAIN | reporter.nih.gov |
| A novel mechanism of immunosuppression in sepsis: Depletion of monocytes and macrophages | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $747,128 | September 20, 2019 | June 30, 2024 | LI, ZHENYU | reporter.nih.gov |
| Dysregulation of Mitochondrial Dynamics in Sepsis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $746,848 | April 1, 2021 | March 31, 2024 | HAILESELASSIE, BEREKETAB | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $743,137 | August 18, 2021 | July 31, 2026 | MCQUILLEN, PATRICK SEAN | reporter.nih.gov |
| Refining Immune Heterogeneity in Pediatric Sepsis Multiple Organ Dysfunction Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $739,487 | August 1, 2025 | April 30, 2030 | REMY, KENNETH EUGENE | reporter.nih.gov |
| Sepsis and the Systemic Cytokine Storm in Aging and Alzheimer Disease Models | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $739,450 | August 15, 2022 | July 31, 2027 | EFRON, PHILIP A | reporter.nih.gov |
| Defining the mitochondrial metabolic regulation of systemic innate inflammation | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $738,401 | July 1, 2024 | April 30, 2029 | MONTEITH, ANDREW J | reporter.nih.gov |
| Clinical Implementation of Molecular Phenotypes of Critical Illness | NIH | National Heart, Lung, and Blood Institute | 2025 | $737,815 | January 28, 2025 | November 30, 2028 | SINHA, PRATIK | reporter.nih.gov |
| The protective role of kidney-derived Tamm Horsfall protein (Uromodulin) in sepsis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $737,040 | August 15, 2023 | July 31, 2027 | LAFAVERS, KAICE | reporter.nih.gov |
| Critical Role of Basophils in the Enhancement of the Innate Immune Response during Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $735,264 | September 15, 2018 | July 31, 2023 | PILIPONSKY, ADRIAN M | reporter.nih.gov |
| Subtyping sepsis in Uganda using clinical, pathogen, and host response profiling | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $732,904 | February 2, 2022 | January 31, 2026 | CUMMINGS, MATTHEW JOHN | reporter.nih.gov |
| Characterizing patients at risk for sepsis through Big Data | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $731,382 | August 1, 2020 | July 31, 2025 | HOLDER, ANDRE L | reporter.nih.gov |
| Mechanistic human studies to prevent Hirschsprung-associated enterocolitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $722,908 | January 1, 2025 | November 30, 2028 | HEUCKEROTH, ROBERT O | reporter.nih.gov |
| Neutrophil Decision Making in Confined Environments in Health and Disease | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $722,400 | May 1, 2010 | March 31, 2024 | IRIMIA, DANIEL | reporter.nih.gov |
| Modulation of Pediatric Sepsis by Virus Persistence | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $721,728 | May 12, 2025 | April 30, 2030 | WEINBERG, JASON BRICE | reporter.nih.gov |
| Mechanisms of PbgA involvement in Salmonella Typhimurium lipid homeostasis for bacterial pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $721,400 | May 1, 2018 | April 30, 2024 | DALEBROUX, ZACHARY DAVID | reporter.nih.gov |
| The impact of the Bundled Payment for Care Improvement Advanced on outcomes for patients with sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 | $721,155 | December 25, 2022 | December 26, 2022 | RYAN, ANDREW M | reporter.nih.gov |
| Automated Multiplex Analyzer for Sepsis and Beyond | NIH | National Institute of General Medical Sciences | 2025 | $720,920 | August 5, 2022 | August 31, 2028 | KUNJAN, KISLAYA | reporter.nih.gov |
| Implementation of Continuum of Care Sepsis Phenotyping and Risk Stratification | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $719,555 | May 1, 2022 | April 30, 2027 | WARDI, GABRIEL | reporter.nih.gov |
| Effect of Mitochondrial Quality Control on Systemic Inflammation and Organ Dysfunction in Pediatric Sepsis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $719,025 | September 1, 2020 | December 31, 2022 | WEISS, SCOTT L | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $718,141 | August 18, 2021 | July 31, 2026 | MEERT, KATHLEEN L. | reporter.nih.gov |
| Determinants and Mechanisms of Efficacy of Peptide Antibiotics as Novel Sepsis Therapy | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $714,303 | August 1, 2018 | July 31, 2024 | DESLOUCHES, BERTHONY | reporter.nih.gov |
| 1/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $713,484 | September 16, 2020 | March 31, 2022 | BOECKH, MICHAEL J | reporter.nih.gov |
| Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $712,827 | September 1, 2022 | June 30, 2027 | MASKARINEC, STACEY A | reporter.nih.gov |
| Personalized vasopressor therapy in patients with septic shock | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $708,473 | September 1, 2022 | August 31, 2027 | BAUER, SETH | reporter.nih.gov |
| Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotyping | NIH | National Institute of General Medical Sciences | 2025 | $705,050 | August 5, 2023 | June 30, 2027 | ATREYA, MIHIR R | reporter.nih.gov |
| Sca-1 signaling, EPC, and the inflammatory response to septic infection | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $702,000 | July 1, 2019 | April 30, 2024 | ZHANG, PING | reporter.nih.gov |
| Investigating the Role of HDL-Associated Serum Amyloid A in Sepsis-Induced Acute Lung Injury and Mortality | NIH | National Heart, Lung, and Blood Institute | 2025 | $699,385 | January 1, 2025 | November 30, 2028 | SHRIDAS, PREETHA | reporter.nih.gov |
| DIscovering SubPhenotypes and ENdotypes in pediatric SEpsis-induced MODS: the DISPENSE Study | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $697,256 | August 1, 2025 | July 31, 2029 | FLORI, HEIDI R | reporter.nih.gov |
| Salivary Diagnostics for Sepsis Screening in the Neonate | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $694,808 | August 9, 2019 | February 28, 2022 | MARON, JILL LAMANNA | reporter.nih.gov |
| Mito-inflammation and sepsis-induced acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $694,398 | August 21, 2025 | May 31, 2029 | BLACK, STEPHEN M | reporter.nih.gov |
| Thromboinflammatory consequences of infection-induced autoimmunity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $692,543 | August 1, 2022 | July 31, 2027 | ZUO, YU | reporter.nih.gov |
| Preventing antimicrobial resistance and infections in hospitalized neonates in low resource settings | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $686,036 | July 13, 2020 | June 30, 2026 | JOHNSON, JULIA | reporter.nih.gov |
| Multimodal Nanoparticles for Severe Inflammation and Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $684,206 | May 21, 2025 | April 30, 2030 | PEARSON, RYAN MATTHEW | reporter.nih.gov |
| The Role of FXR on the Intestinal Barrier in Acute Injury. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $683,424 | April 1, 2020 | December 31, 2024 | GAYER, CHRISTOPHER | reporter.nih.gov |
| Functional Immune Phenotyping of Sepsis Patients: Integrating Microphysiological Assays, Omics and In Silico Modeling | NIH | National Heart, Lung, and Blood Institute | 2025 | $683,299 | September 5, 2025 | June 30, 2029 | KILPATRICK, LAURIE E | reporter.nih.gov |
| Mitochondrial deubiquitinase USP30 regulates cell metabolism-mediated miRNA biogenesis and microvascular inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $678,803 | February 1, 2025 | November 30, 2028 | ZHAO, YUTONG | reporter.nih.gov |
| Optimizing methods of clinical sample processing for scRNA-seq and mechanistic studies in sepsis to enable reliable, reproducible, and high-yield multi-center collection efforts | NIH | National Institute of General Medical Sciences | 2025 | $676,179 | January 1, 2023 | December 31, 2026 | FILBIN, MICHAEL | reporter.nih.gov |
| Optimization of a rapid assay to quantify circulating glycosaminoglycans and identify vascular endotypes of sepsis | NIH | National Institute of General Medical Sciences | 2025 | $675,868 | July 14, 2023 | June 30, 2027 | SCHMIDT, ERIC PETER | reporter.nih.gov |
| The contribution of respiratory burst to antibiotic failure in Staphylococcus aureus bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $674,578 | August 22, 2022 | July 31, 2024 | CONLON, BRIAN PATRICK | reporter.nih.gov |
| Targeting cardiovascular events to improve patient outcomes after sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $668,389 | July 15, 2018 | April 30, 2023 | WALKEY, ALLAN J. | reporter.nih.gov |
| Role of Macrophage Efferocytosis in Ozone-Induced ARDS | NIH | National Institute of Environmental Health Sciences | 2022 to 2024 | $667,515 | September 22, 2020 | August 31, 2025 | RADBEL, JARED M. | reporter.nih.gov |
| The regulation and function of platelet FcARIIA in sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $666,100 | September 21, 2020 | June 30, 2026 | MIDDLETON, ELIZABETH ANNE | reporter.nih.gov |
| STeroids and enhanced Antibiotics for the treatment of patients in Africa with Refractory Sepsis: STARS trial | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $664,331 | September 20, 2025 | August 31, 2030 | HEYSELL, SCOTT K | reporter.nih.gov |
| Study of Treatment's Echocardiographic Mechanisms (CLOVERS-STEM) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $662,051 | June 10, 2019 | May 31, 2025 | BROWN, SAMUEL MORRIS | reporter.nih.gov |
| Randomized Trial of non-Surgical Therapy and Oral Hygiene Instruction to Reduce Risk of Infective Endocarditis | NIH | National Institute of Dental & Craniofacial Research | 2022 | $660,849 | February 1, 2022 | January 31, 2023 | LOCKHART, PETER B | reporter.nih.gov |
| Brainstem Cholinergic Circuitries in the Inflammatory Reflex during Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $660,000 | April 1, 2018 | March 31, 2024 | PAVLOV, VALENTIN ATANASSOV | reporter.nih.gov |
| Neutrophils in Sepsis: Role of CIRP | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $660,000 | September 1, 2018 | June 30, 2025 | AZIZ, MONOWAR | reporter.nih.gov |
| Advancing Neurosymbolic AI for Smart and Trustworthy Healthcare | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $653,230 | August 6, 2025 | May 31, 2029 | LONG, QI | reporter.nih.gov |
| Operationalizing the RAGE Axis in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $647,998 | March 15, 2020 | February 28, 2026 | JONES, TIFFANIE KAE | reporter.nih.gov |
| Role of purinergic signaling in pediatric multi-organ failure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $640,045 | April 15, 2023 | August 31, 2025 | JUNGER, WOLFGANG G | reporter.nih.gov |
| Visceral fat gamma delta T cells in sepsis pathogenesis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $640,000 | September 1, 2018 | May 31, 2023 | STARR, MARLENE ELENA | reporter.nih.gov |
| A multimodal approach for immunotherapy of Staphylococcus aureus bacteremia | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $638,953 | August 22, 2025 | July 31, 2030 | AMAN, M JAVAD | reporter.nih.gov |
| Microfluidic Assessment of Clinical Outcomes in Preterm Newborns | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $635,840 | August 9, 2017 | May 31, 2023 | MOLDAWER, LYLE L | reporter.nih.gov |
| Etiology of Microvascular Changes in Gram-positive Sepsis: Mechanisms and Therapeutic Options | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $632,000 | June 1, 2012 | June 30, 2024 | ENKHBAATAR, PERENLEI | reporter.nih.gov |
| Pediatric septic acute kidney injury: personalizing antibiotic dosing through understanding acute kidney injury risk factors and biomarker profiles | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $630,109 | January 15, 2020 | March 31, 2025 | FITZGERALD, JULIE C. HOLLOWS | reporter.nih.gov |
| Collaborative Pediatric Critical Care Research Network - Clinical Site | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $628,740 | August 18, 2021 | July 31, 2026 | MADDUX, ALINE BERNARD | reporter.nih.gov |
| Sepsis phenotypes at risk for infections caused by multidrug resistant Gram-negative bacilli: elucidating the impact of sepsis definition and patient case mix on prediction performance | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $622,709 | September 10, 2020 | August 31, 2024 | VAZQUEZ GUILLAMET, MARIA CRISTINA | reporter.nih.gov |
| Role of miRNA-TLR7 signaling in platelet activation and dysfunction in sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $620,600 | September 1, 2020 | May 31, 2025 | WILLIAMS, BRITTNEY | reporter.nih.gov |
| Mechanisms underlying regulation of intestinal epithelial homeostasis in sepsis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $616,730 | February 15, 2020 | January 31, 2025 | TAN, XIAO-DI | reporter.nih.gov |
| Beclin-1 in Sepsis-Induced Cardiac Dysfunction | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $616,000 | September 25, 2014 | August 31, 2025 | ZANG, QUN SOPHIA | reporter.nih.gov |
| Development of a Novel Injectable Antibiotic to Treat Serious Multidrug-resistant Gram-positive Infections | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $613,907 | May 4, 2023 | August 31, 2025 | KEEDY, KARA S | reporter.nih.gov |
| Lung Macrophage Memory Development and Responses in Secondary Pneumonia and Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $610,868 | August 27, 2021 | July 31, 2025 | MISHRA, BIBHUTI BHUSAN | reporter.nih.gov |
| Using data science to measure the impact of opioid agonist therapy in patients admitted with Staphylococcus aureus bloodstream infections | NIH | National Institute on Drug Abuse | 2021 to 2023 | $609,120 | June 15, 2019 | May 31, 2024 | GOODMAN, DAVID | reporter.nih.gov |
| Platelet-Leukocyte Interactions in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $606,165 | September 1, 2021 | August 31, 2026 | RONDINA, MATTHEW THOMAS | reporter.nih.gov |
| Roles of Sectm1a in macrophages and cardiac function during sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $605,516 | April 1, 2019 | March 31, 2023 | FAN, GUO-CHANG | reporter.nih.gov |
| Targeting macrophage maladaptation for bacterial sepsis treatment | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $597,310 | June 15, 2023 | May 31, 2026 | ZHU, XUEWEI | reporter.nih.gov |
| Biomarker-enhanced Artificial Intelligence-Based Pediatric Sepsis Screening Tool Towards Early Recognition and Personalized Therapeutics | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $597,223 | March 1, 2022 | February 28, 2025 | KOUTROULIS, IOANNIS | reporter.nih.gov |
| PED Screen: Pediatric Sepsis EHR Registry, Clinical Outcomes, and Predictive Model | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $597,143 | February 1, 2017 | January 31, 2023 | ALPERN, ELIZABETH RACHEL | reporter.nih.gov |
| SCH: Improving Early Prediction and Decision-Making for Sepsis with Human-AI Collaboration | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $594,506 | July 17, 2024 | May 31, 2028 | ZHANG, PING | reporter.nih.gov |
| AstraDx: Sub-Hour AST Via Computational Image Processing | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $593,280 | August 1, 2022 | July 31, 2024 | FLOREZ, JONATHAN | reporter.nih.gov |
| The µSiM-hNVU - a human BBB platform for the study of brain injury mechanisms during systemic infection | NIH | National Heart, Lung, and Blood Institute | 2021 | $593,001 | September 3, 2020 | August 31, 2022 | MCGRATH, JAMES L | reporter.nih.gov |
| Mitochondrial metabolism in microbial sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $591,274 | September 15, 2019 | July 31, 2024 | WEN, HAITAO | reporter.nih.gov |
| Cellular and Metabolic Dysfunction in Sepsis-Induced Immune Paralysis | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $588,060 | September 1, 2023 | August 31, 2026 | TORRES, LISA KRISTINA | reporter.nih.gov |
| Role of Toll-like Receptor 9 in Fibroblastic Reticular Cell-based Therapy for Intra-abdominal Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $587,008 | February 24, 2020 | July 22, 2022 | DENG, MEIHONG | reporter.nih.gov |
| Novel cysteinyl leukotriene receptor signaling in regulating cellular, and molecular events in lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $579,309 | June 9, 2025 | February 28, 2029 | PARUCHURI, SAILAJA | reporter.nih.gov |
| Developing a Precision Medicine Approach to Pediatric Sepsis-Associated Acute Kidney Injury: Identification of Unique Subphenotypes and Strategies for Bedside Implementation | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $576,172 | July 1, 2023 | June 30, 2028 | STANSKI, NATALJA L. | reporter.nih.gov |
| Mechanisms of cardiomyocyte dysfunction in pediatric septic shock | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $576,072 | February 1, 2023 | January 31, 2027 | LAUTZ, ANDREW JOHN | reporter.nih.gov |
| Platelet Regulation of Monocyte Responses in Vascular Inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $573,261 | August 1, 2025 | April 30, 2029 | MORRELL, CRAIG N | reporter.nih.gov |
| Improving diagnosis of post-traumatic sepsis using plasma microbial DNA sequencing | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $571,149 | January 1, 2023 | December 31, 2027 | KISAT, MEHREEN T | reporter.nih.gov |
| Molecular Signatures of Early-Onset Neonatal Sepsis in Umbilical Cord Blood | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $568,620 | February 4, 2019 | January 31, 2025 | MITHAL, LEENA BHATTACHARYA | reporter.nih.gov |
| SPOT-IT: Sepsis Prediction in Oncology Through Implementation Science and Technology | NIH | National Cancer Institute | 2024 to 2025 | $566,796 | June 7, 2024 | May 31, 2029 | LYONS, PATRICK G | reporter.nih.gov |
| Integrated physiomarker, biomarker and clinical predictive analytics for early warning of sepsis and necrotizing enterocolitis in very low birth weight infants. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $566,690 | July 1, 2019 | June 30, 2025 | SULLIVAN, BRYNNE ARCHER | reporter.nih.gov |
| A Sepsis Transition Program to Reduce Morbidity and Mortality in High Risk Individuals | NIH | National Institute of Nursing Research | 2023 | $562,398 | July 23, 2019 | April 30, 2025 | KOWALKOWSKI, MARC | reporter.nih.gov |
| Calcium homeostasis and cellular fitness in sepsis | NIH | National Institute of General Medical Sciences | 2022 | $555,116 | September 1, 2022 | June 30, 2023 | ROSENGART, MATTHEW RANDALL | reporter.nih.gov |
| Affinity Reagents and Sensor Platform Development for Blood Biochemical Monitoring | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2024 | $549,024 | April 1, 2022 | December 31, 2024 | PAN, JING | reporter.nih.gov |
| Mitochondrially Targeted Therapies for Sepsis Induced Diaphragm Dysfunction | NIH | National Heart, Lung, and Blood Institute | 2021 | $542,781 | July 1, 2018 | May 31, 2023 | CALLAHAN, LEIGH A | reporter.nih.gov |
| Targeting NINJ1-mediated Plasma Membrane Rupture to Prevent Thrombosis | NIH | National Heart, Lung, and Blood Institute | 2025 | $538,808 | September 15, 2025 | June 30, 2030 | WU, CONGQING | reporter.nih.gov |
| Targeting the VHR phosphatase for the treatment of sepsis in COVID-19 patients | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $536,250 | April 6, 2021 | September 30, 2023 | TAUTZ, LUTZ | reporter.nih.gov |
| Novel antimicrobial agents to overcome antibiotic resistant Pseudomonas and MRSA respiratory infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $524,705 | July 12, 2017 | June 30, 2024 | DI, YUANPU PETER | reporter.nih.gov |
| Role of purinergic signaling in pediatric multi-organ failure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $521,793 | March 20, 2019 | February 28, 2023 | JUNGER, WOLFGANG G | reporter.nih.gov |
| Biobank of small extracellular vesicles for pediatric sepsis | NIH | National Institute of General Medical Sciences | 2025 | $516,797 | August 17, 2023 | June 30, 2026 | ZINGARELLI, BASILIA | reporter.nih.gov |
| Development of Novel RhoA Nitration Inhibitory Peptides for the Treatment of Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $516,250 | September 1, 2025 | July 31, 2027 | BLACK, STEPHEN M | reporter.nih.gov |
| Understanding the Platelet-CD8+ T Cell Interactions in Sepsis | NIH | National Institute of General Medical Sciences | 2025 | $504,644 | August 15, 2025 | July 31, 2030 | GUO, LI | reporter.nih.gov |
| Syndecan Regulation of Sepsis Host Defense | NIH | National Heart, Lung, and Blood Institute | 2021 | $501,434 | August 15, 2018 | June 30, 2023 | PARK, PYONG WOO | reporter.nih.gov |
| The role of extracellular vesicles in septic encephalopathy metabolism and immunity | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $500,500 | December 6, 2023 | November 30, 2026 | KOUTROULIS, IOANNIS | reporter.nih.gov |
| Genomic diversity of Candida bloodstream infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $498,557 | March 1, 2021 | February 28, 2025 | NGUYEN, M. HONG THI | reporter.nih.gov |
| Cell-free hemoglobin-oxidized LDL-LOX-1 axis and microvascular hyperpermeability during sepsis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $498,000 | August 1, 2024 | July 31, 2027 | MEEGAN, JAMIE E | reporter.nih.gov |
| Deciphering the pathogenesis of an enteric pathogen in neonatal and immunodeficient mice | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $497,998 | August 11, 2022 | April 30, 2027 | CABALLERO FLORES, GUSTAVO | reporter.nih.gov |
| Mapping the unique features of fetal and neonatal hematopoietic stem and progenitor cells conferring susceptibility to inflammation and infection | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $496,368 | September 15, 2020 | July 27, 2024 | COLLINS, AMELIE | reporter.nih.gov |
| Reduction of bloodstream infections from oral organisms in pediatric stem cell transplant: a randomized, multicenter, double-blind, placebo-controlled study evaluating twice daily oral xylitol | NIH | National Institute of Dental & Craniofacial Research | 2021 | $490,242 | May 6, 2021 | August 31, 2022 | DANDOY, CHRISTOPHER EUGENE | reporter.nih.gov |
| Unravelling the role of aDb2 as a novel complement receptor in lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $489,500 | July 25, 2025 | June 30, 2027 | KOUTSOGIANNAKI, SOPHIA | reporter.nih.gov |
| Genetic Variants of Immune Dysregulation and Thrombotic Microangiopathy in Severe Pediatric Sepsis Induced Organ Dysfunction | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $489,244 | June 1, 2023 | May 31, 2027 | KERNAN, KATHRYN MARY | reporter.nih.gov |
| Type 2 Immune Responses in Endotoxemia-induced Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $486,109 | July 1, 2025 | June 30, 2027 | JACOBSEN, ELIZABETH A | reporter.nih.gov |
| Characterizing the preterm infant skin microbiome and microbial shifts that precede neonatal late onset sepsis (LOS) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $484,704 | April 1, 2023 | March 31, 2027 | SCHOCH, JENNIFER JANE | reporter.nih.gov |
| Feasibility of early detection of infection and sepsis in the home | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $484,353 | July 10, 2023 | June 30, 2025 | CHAN, RAYMOND C | reporter.nih.gov |
| Role of Clec2d-DAMP interactions in the pathophysiology of tissue injury and sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $480,896 | June 20, 2017 | May 31, 2023 | ROCK, KENNETH L | reporter.nih.gov |
| Role and Regulation of the Secreted Proteases of Staphylococcus aureus | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $480,522 | July 23, 2025 | June 30, 2030 | SHAW, LINDSEY NEIL | reporter.nih.gov |
| Optimization of a rapid assay to quantify circulating glycosaminoglycans and identify vascular endotypes of sepsis | NIH | National Institute of General Medical Sciences | 2023 to 2024 | $479,820 | July 14, 2023 | June 30, 2025 | SCHMIDT, ERIC PETER | reporter.nih.gov |
| Stabilizing mitochondria in sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $479,620 | November 29, 2018 | June 30, 2023 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| Aging-associated changes in gut microbiome drive sepsis severity | NIH | National Institute on Aging | 2021 to 2023 | $479,520 | April 1, 2019 | September 30, 2024 | COLBERT, JAMES F | reporter.nih.gov |
| Mechanisms regulating neutrophil proinflammatory activity in sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $479,249 | January 24, 2025 | December 31, 2029 | CHO, JAEHYUNG | reporter.nih.gov |
| Pediatric Sepsis Biorepository and Clinical Database | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $478,204 | April 11, 2022 | March 31, 2024 | BALAMUTH, FRANCES B | reporter.nih.gov |
| The Sepsis ClinicAl Resource And Biorepository (SCARAB) Project | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $474,494 | January 1, 2022 | February 14, 2024 | BASTARACHE, JULIE ANNE | reporter.nih.gov |
| Analyzing the mechanism of exosome mediated DNA Methyltransferase activity during sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $474,017 | April 1, 2020 | August 31, 2023 | WISLER, JON R | reporter.nih.gov |
| Novel point-of-care liquid biopsy for early detection of sepsis-associated organ damage | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $473,937 | July 25, 2025 | June 30, 2027 | KARABACAK, NEZIHI MURAT | reporter.nih.gov |
| Longitudinal Assessment of Beta-lactam Antibiotic Exposure in in Critically Ill Children with Sepsis in the PICU to Predict Dosing Requirements | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $471,213 | July 28, 2018 | February 29, 2024 | BRADLEY, JOHN S | reporter.nih.gov |
| Novel exosomal niches for alveolar stem cell-based repair of ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 | $469,701 | September 1, 2017 | April 30, 2023 | JI, HONG-LONG | reporter.nih.gov |
| Genetic Analyses of bacteremia non-typhoidal Salmonella | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $469,500 | December 1, 2022 | November 30, 2025 | WORLEY, MICAH | reporter.nih.gov |
| Dynactin 4 regulation of lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $466,844 | January 1, 2018 | November 30, 2022 | CHEN, PETER | reporter.nih.gov |
| Within-host diversity of Gram negative bacteria from bloodstream infections | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $466,480 | November 21, 2023 | October 31, 2026 | NGUYEN, M. HONG THI | reporter.nih.gov |
| Screening for Fluoroquinolone-Resistant Viridans Group Streptococci to Individualize Infection Prevention Strategies in Neutropenic Patients | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $466,125 | June 7, 2024 | May 31, 2027 | SATLIN, MICHAEL JOSEPH | reporter.nih.gov |
| Advancing Sepsis Biology and Care Through the Power of Modern Biobanks | NIH | National Institute of General Medical Sciences | 2025 | $462,981 | August 15, 2025 | July 31, 2030 | ASGARI, SAMIRA | reporter.nih.gov |
| Polyclonality of carbapenem resistant Enterobacteriaceae bloodstream infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $461,686 | November 12, 2020 | October 31, 2023 | CLANCY, CORNELIUS J | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, TN | 13 | $31.6 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 33 | $30 million | 0 | $0 |
| Helixbind, Inc. | Boxborough, MA | 10 | $28.1 million | 0 | $0 |
| University of Florida | Gainesville, FL | 20 | $27.6 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 30 | $27.1 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 23 | $26.6 million | 0 | $0 |
| Ohio State University | Columbus, OH | 20 | $24.9 million | 0 | $0 |
| Duke University | Durham, NC | 15 | $24.9 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 19 | $20.2 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 12 | $20 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 15 | $18 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 12 | $17.1 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 13 | $16.5 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 7 | $15.4 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 13 | $14.8 million | 0 | $0 |
| Feinstein Institute for Medical Research | Manhasset, NY | 12 | $14.7 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 9 | $14 million | 0 | $0 |
| Washington University | Saint Louis, MO | 13 | $13.8 million | 0 | $0 |
| University of Rochester | Rochester, NY | 9 | $12.3 million | 0 | $0 |
| Emory University | Atlanta, GA | 14 | $12.2 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 14 | $12.1 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 10 | $11.9 million | 0 | $0 |
| Oklahoma Medical Research Foundation | Oklahoma City, OK | 3 | $11.6 million | 0 | $0 |
| Scanogen, Inc. | Baltimore, MD | 4 | $11.3 million | 0 | $0 |
| Rhode Island Hospital | Providence, RI | 7 | $11.1 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 16 | $11 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 7 | $10.1 million | 0 | $0 |
| Fred Hutchinson Cancer Center | Seattle, WA | 2 | $8.8 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 5 | $8.7 million | 0 | $0 |
| Lurie Children's Hospital of Chicago | Chicago, IL | 7 | $8.6 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 7 | $8.1 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 8 | $8 million | 0 | $0 |
| University of Washington | Seattle, WA | 7 | $8 million | 0 | $0 |
| East Tennessee State University | Johnson City, TN | 7 | $7.7 million | 0 | $0 |
| University of Iowa | Iowa City, IA | 8 | $7.7 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 7 | $7.3 million | 0 | $0 |
| Prenosis, Inc. | Champaign, IL | 4 | $7.3 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 7 | $7 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 8 | $6.7 million | 0 | $0 |
| Redeemer's University | Ede | 1 | $6.4 million | 0 | $0 |
| West Virginia University Research Corporation | Morgantown, WV | 4 | $6.4 million | 0 | $0 |
| Stanford University | Stanford, CA | 6 | $6.4 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 7 | $6.4 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 3 | $6.3 million | 0 | $0 |
| Yale University | New Haven, CT | 4 | $5.8 million | 0 | $0 |
| Arkansas Children's Hospital Res Inst | Little Rock, AR | 1 | $5.6 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 9 | $5.6 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 4 | $5.6 million | 0 | $0 |
| Hackensack University Medical Center | Hackensack, NJ | 2 | $5.6 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 8 | $5.5 million | 0 | $0 |
| Louisiana State University | Baton Rouge, LA | 4 | $5.2 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 10 | $5 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 3 | $4.9 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 3 | $4.7 million | 0 | $0 |
| Methodist Hospital Research Institute | Houston, TX | 3 | $4.7 million | 0 | $0 |
| Research Inst Nationwide Children's Hosp | Columbus, OH | 4 | $4.4 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 4 | $4.4 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 6 | $4.3 million | 0 | $0 |
| Tufts University Boston | Boston, MA | 2 | $4 million | 0 | $0 |
| University of Tennessee Health Sci CTR | Memphis, TN | 4 | $3.7 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 3 | $3.7 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 6 | $3.6 million | 0 | $0 |
| Carolinas Medical Center | Charlotte, NC | 4 | $3.5 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 3 | $3.5 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 6 | $3.5 million | 0 | $0 |
| University of Oklahoma HLTH Sciences CTR | Oklahoma City, OK | 3 | $3.4 million | 0 | $0 |
| Ihc Health Services, Inc. | Salt Lake City, UT | 4 | $3.3 million | 0 | $0 |
| SUNY at Stony Brook | Stony Brook, NY | 2 | $3.3 million | 0 | $0 |
| Loyola University Chicago | Maywood, IL | 5 | $3.3 million | 0 | $0 |
| Nubad, LLC | Greer, SC | 1 | $3.2 million | 0 | $0 |
| University of Texas at Dallas | Richardson, TX | 2 | $3.1 million | 0 | $0 |
| Augusta University | Augusta, GA | 2 | $3.1 million | 0 | $0 |
| University of Illinois at Urbana-Champaign | Urbana, IL | 2 | $3.1 million | 0 | $0 |
| Arietis | Boston, MA | 1 | $3 million | 0 | $0 |
| Albany Medical College | Albany, NY | 4 | $3 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 2 | $3 million | 0 | $0 |
| University of California-Riverside | Riverside, CA | 2 | $2.8 million | 0 | $0 |
| Virginia Polytechnic Institute and State University | Blacksburg, VA | 3 | $2.8 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 5 | $2.7 million | 0 | $0 |
| University of South Florida | Tampa, FL | 3 | $2.6 million | 0 | $0 |
| University of Connecticut SCH of Med/dnt | Farmington, CT | 2 | $2.5 million | 0 | $0 |
| Aqualung Therapeutics Corp. | Juno Beach, FL | 1 | $2.5 million | 0 | $0 |
| Prothera Biologics, LLC | Providence, RI | 2 | $2.4 million | 0 | $0 |
| University of Chicago | Chicago, IL | 2 | $2.4 million | 0 | $0 |
| Prokaryotics, Inc. | Union, NJ | 2 | $2.4 million | 0 | $0 |
| Kaiser Foundation Research Institute | Oakland, CA | 1 | $2.3 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 2 | $2.2 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 4 | $2.2 million | 0 | $0 |
| Cohere-Med, Inc. | Burlingame, CA | 1 | $2.1 million | 0 | $0 |
| Infotech Soft, Inc. | Miami, FL | 1 | $2 million | 0 | $0 |
| Dascena, Inc. | Hayward, CA | 1 | $2 million | 0 | $0 |
| Dupage Medical Technology, Inc. | Chicago, IL | 1 | $2 million | 0 | $0 |
| Creighton University | Omaha, NE | 1 | $2 million | 0 | $0 |
| Specific Diagnostics, Inc. | Mountain View, CA | 1 | $2 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 1 | $2 million | 0 | $0 |
| Abvacc, Inc. | Rockville, MD | 2 | $1.9 million | 0 | $0 |
| Ohio University | Athens, OH | 1 | $1.9 million | 0 | $0 |
| Wistar Institute | Philadelphia, PA | 1 | $1.9 million | 0 | $0 |
| Children's Research Institute | Washington, DC | 3 | $1.8 million | 0 | $0 |
| Cornell University | Ithaca, NY | 2 | $1.8 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 376 | $194,341,461 | 0 | $0 |
| 2024 | 374 | $180,350,230 | 0 | $0 |
| 2023 | 387 | $184,341,973 | 0 | $0 |
| 2022 | 370 | $168,864,452 | 0 | $0 |
| 2021 | 367 | $156,583,857 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
| Open opportunity | Number | Agency | Listing | Closes | Award ceiling | Why it matches |
|---|---|---|---|---|---|---|
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) | PA-24-185 | NIH | May 7, 2027 | Not listed | Notice number printed on 6 awards here | |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) | PA-24-182 | NIH | May 8, 2027 | Not listed | Notice number printed on 4 awards here | |
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) | PA-24-254 | NIH | July 12, 2027 | Not listed | Notice number printed on 3 awards here | |
| Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required) | RFA-AI-27-002 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required) | RFA-AI-27-005 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) | PAR-25-370 | NIH | 93.855 | November 16, 2026 | $50,000 | Same assistance listing 93.855 as 243 awards here |
| Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) | PAR-25-369 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) | PAR-25-371 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) | PAR-25-379 | NIH | 93.855 | January 7, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| HIV/AIDS Clinical Trials Network Leadership and Operations Centers | RFA-AI-28-001 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| HIV/AIDS Clinical Trials Network Laboratory Centers | RFA-AI-28-002 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| HIV/AIDS Clinical Trials Network Statistical and Data Management Centers | RFA-AI-28-003 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| HIV/AIDS Clinical Trials Network Clinical Trials Units | RFA-AI-28-004 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases | RFA-AI-28-014 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Immune Tolerance Network (UM1 Clinical Trial Required) | RFA-AI-28-005 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed) | RFA-AI-28-012 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed) | RFA-AI-28-024 | NIH | 93.855 | February 11, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed) | RFA-LM-28-001 | NIH | 93.855 | February 11, 2027 | $775,000 | Same assistance listing 93.855 as 243 awards here |
| NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) | PA-27-100 | NIH | 93.855 | April 5, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
| NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) | PA-27-102 | NIH | 93.855 | April 5, 2027 | Not listed | Same assistance listing 93.855 as 243 awards here |
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.