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Data / Research funding / Regenerative Medicine

Regenerative Medicine: 4,397 NIH awards ($4.5B) to 515 organizations

4,397 NIH awards ($4.5B) in the NIH spending category Regenerative Medicine, to 515 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 4,397 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.NIHNational Heart, Lung, and Blood Institute2021 to 2025$36,418,175September 15, 2017August 31, 2031HAMADANI, MEHDI HUSSAINreporter.nih.gov
A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy ResearchNIHNational Cancer Institute2021 to 2025$30,268,190March 1, 1998February 29, 2028SHAW, BRONWENreporter.nih.gov
Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical TrialNIHNational Institute on Aging2021 to 2025$28,784,116August 15, 2019April 30, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)NIHNational Institute of Dental & Craniofacial Research2021 to 2024$25,635,194May 7, 2020April 30, 2026CHAI, YANGreporter.nih.gov
Michigan-Pittsburgh-Wyss Regenerative Medicine Resource Center: Advancing Dental, Oral, and Craniofacial Regeneration to Clinical Trial InitiationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$24,937,885May 1, 2020April 30, 2026KOHN, DAVID H.reporter.nih.gov
Idaho INBRE ProgramNIHNational Institute of General Medical Sciences2021 to 2025$21,939,274September 30, 2001August 31, 2030BOHACH, CAROLYN HOVDEreporter.nih.gov
Parkinsons Disease Scalable iPSC Autologous Cell TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$7,528,144January 1, 2020December 31, 2025HALLETT, PENELOPE JANEreporter.nih.gov
TRANSPIRE: A Prospective Cohort Study of Lung Injury After Hematopoietic Stem Cell Transplant in Children.NIHNational Heart, Lung, and Blood Institute2021 to 2025$7,251,380September 1, 2021May 31, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Exosomes as mediators of cardiac injury and repairNIHNational Heart, Lung, and Blood Institute2021 to 2025$7,022,243September 1, 2017June 30, 2029KISHORE, RAJreporter.nih.gov
Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and RegenerationNIHNational Institute of General Medical Sciences2021 to 2025$6,903,660June 1, 2021May 31, 2026READY, JOSEPH Mreporter.nih.gov
Tissue Engineering Resource CenterNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$6,721,905September 16, 2019February 28, 2029VUNJAK-NOVAKOVIC, GORDANAreporter.nih.gov
An Intranasal GDNF Gene Therapy for Opioid Relapse ReductionNIHNational Institute on Drug Abuse2021$6,693,512September 15, 2021August 31, 2025WASZCZAK, BARBARA LEEreporter.nih.gov
Molecular Circuits in the Hematopoietic Stem Cell NicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,422,507August 15, 2020May 31, 2025DALEY, GEORGE Qreporter.nih.gov
Mentoring Research Excellence in Aging and Regenerative MedicineNIHNational Institute of General Medical Sciences2022 to 2025$6,297,053June 1, 2022May 31, 2027JAZWINSKI, S MICHALreporter.nih.gov
Restoration of Grasp and Reach in Cervical Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,968,318March 1, 2018August 31, 2025KILGORE, KEVIN L.reporter.nih.gov
Novel Biologic Therapies for GVHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$5,851,412February 1, 2010June 30, 2026KEAN, LESLIE Sreporter.nih.gov
Accelerating photoreceptor replacement therapy with in-vivo cellular imaging of retinal functionNIHNational Eye Institute2021 to 2025$5,733,511September 30, 2021January 31, 2027MCGREGOR, JULIETTE ELIZABETHreporter.nih.gov
Overcoming Neurogenic “Meta-Inflammation” to Promote Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,600,627May 1, 2019April 30, 2027POPOVICH, PHILLIP Greporter.nih.gov
A Human iPSC-based Cell Therapy for Canavan DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,276,950June 15, 2021May 31, 2027SHI, YANHONGreporter.nih.gov
Continuous Neurogenesis in the Mammalian HippocampusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,244,633May 1, 2020April 30, 2028SONG, HONGJUNreporter.nih.gov
Fecal Microbiota Transplantation and Fiber for the Treatment of Graft-versus-host Disease After Hematopoietic Cell TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$5,128,451September 1, 2023June 30, 2027FREDRICKS, DAVID NEALreporter.nih.gov
Novel Strategies to Improve Blood Transfusion PracticeNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,119,758August 15, 2022July 31, 2027LUO, HONGBO Rreporter.nih.gov
A Precision Medicine Approach for the Study of Targetable Pathways in Vascular DementiaNIHNational Institute on Aging2022 to 2025$5,086,657February 1, 2022November 30, 2026GOATE, ALISON Mreporter.nih.gov
Adaptable tissue-specific endothelial cells for organ regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2025$5,071,342April 1, 2020March 31, 2027RAFII, SHAHINreporter.nih.gov
Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)NIHNational Heart, Lung, and Blood Institute2023 to 2025$5,061,587May 10, 2021April 30, 2027TRAPNELL, BRUCE Creporter.nih.gov
Dietary Restriction, GH/IGF-1 & Mechanisms of Cellular Protection and RegenerationNIHNational Institute on Aging2021 to 2023$5,057,227February 15, 2018January 31, 2024LONGO, VALTER D.reporter.nih.gov
Mucus-degrading intestinal bacteria and toxicities of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,032,505September 21, 2024July 31, 2029JENQ, ROBERTreporter.nih.gov
1/2A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic AnemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,023,972April 1, 2022March 31, 2029SHAW, BRONWENreporter.nih.gov
Center for Modular Manufacturing of Structural TissuesNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$4,984,439June 1, 2016May 31, 2027WELTER, JEAN Freporter.nih.gov
Investigating the heterogeneity and coordination of hematopoietic stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,840,269August 1, 2020July 31, 2027LU, RONGreporter.nih.gov
Program to promote lung regeneration and block fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,819,926February 15, 2020February 14, 2026CHAPMAN, HAROLD Areporter.nih.gov
Novel Stem Cell Immunotherapy for MDR-TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,800,190June 4, 2021May 31, 2026JAGANNATH, CHINNASWAMYreporter.nih.gov
A Phase I Clinical Trial Testing Feasibility of Hematopoietic Stem Cell Gene Therapy Using Platelet Factor VIII to Safely Improve Hemostasis for Severe Hemophilia A with Inhibitory AntibodiesNIHNational Heart, Lung, and Blood Institute2021 to 2023$4,780,411April 5, 2019March 31, 2026WILCOX, DAVID ALLENreporter.nih.gov
Defining mechanisms driving salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,717,861September 18, 2018June 30, 2026KNOX, SARAH MONICAreporter.nih.gov
Altering Cardiac Cell Fate for Heart RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,621,749January 13, 2021November 30, 2027QIAN, LIreporter.nih.gov
Cell signaling in development and regenerationNIHNational Institute of General Medical Sciences2021 to 2025$4,582,546May 6, 2016July 9, 2026JIANG, JINreporter.nih.gov
Completion of Non-clinical long-term GLP safety and GMP manufacture for first-in-class neuron regenerative therapy, NNI-362 Phase 2 POC AD trialNIHNational Institute on Aging2023 to 2024$4,543,556September 1, 2023August 31, 2025KELLEHER-ANDERSSON, JUDITH Areporter.nih.gov
A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,411,202December 21, 2016June 30, 2026SACHA, JONAH B.reporter.nih.gov
Cell-cell interactions governing lung epithelial progenitor cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,407,300March 15, 2020January 31, 2027KIM, CARLA F.reporter.nih.gov
Progenitor Regulation in Craniofacial Development and RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$4,376,497September 14, 2017June 30, 2026CRUMP, GAGE Dreporter.nih.gov
Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,345,357December 16, 2015May 31, 2028WU, JOSEPH C.reporter.nih.gov
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$4,203,696August 15, 2020May 31, 2025GRIMES, H. LEIGHTONreporter.nih.gov
Small molecule targeting an epigenetic regulator for the treatment of osteoarthritisNIHNational Institute on Aging2021 to 2024$4,178,124September 30, 2021May 2, 2025ADORNO, MADDALENAreporter.nih.gov
Genome-Wide Discovery and Translational Research for Neural RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,147,990December 1, 2016November 30, 2025STRITTMATTER, STEPHEN Mreporter.nih.gov
Clinical and genetic risk factors associated with adverse long-term health outcomes after curative therapies in individuals with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,065,243March 15, 2021February 28, 2027DEBAUN, MICHAEL R.reporter.nih.gov
Base editing and prime editing for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,000,055January 1, 2021June 30, 2030WEISS, MITCHELL Jreporter.nih.gov
Consortium on Intestinal Regeneration and Fetal Reversion: from Atlas to TherapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$4,000,000September 1, 2024June 30, 2029KLEIN, OPHIR Dreporter.nih.gov
Impact of chronic alcohol consumption on the functional and epigenetic landscapes of monocytes and their progenitorsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,998,523September 1, 2020August 31, 2029MESSAOUDI, ILHEMreporter.nih.gov
Combining Targeted RIT and Synergistic Novel Agent-RenewalNIHNational Cancer Institute2021 to 2025$3,984,924June 1, 2020May 31, 2027OROZCO, JOHNNIE JOSEreporter.nih.gov
Engineered Stem Cells for Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,984,462February 1, 2018March 31, 2027REGNIER, MICHAELreporter.nih.gov
BIOREPOSITORY OF HUMAN INDUCED PLURIPOTENT STEM CELLSFORCARDIOVASCULAR DISEASES (BHIPSC-CVD)- TASK A. CORE STUDY OPERATIONSNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,969,819September 1, 2020August 31, 2025WU, JOSEPHreporter.nih.gov
Mesenchymal Vascular Progenitor Depletion Promotes Lung Aging and Susceptibility to EmphysemaNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,964,079January 1, 2022December 31, 2028MAJKA, SUSAN Mreporter.nih.gov
Pulmonary Valved Graft with Regeneration Potential for Pediatric PatientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,958,584May 24, 2019February 28, 2027HOUDE, AJAYreporter.nih.gov
Synergistic white matter injury from diesel exhaust particulate and chronic cerebral hypoperfusion exposures: Interaction between the Nogo/NgR1 receptor pathway and extravascular fibrinogen toxicityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,929,367September 20, 2022August 31, 2027MACK, WILLIAM Jreporter.nih.gov
Cardiac lineage determination and nuclear architectureNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,927,168January 1, 2018December 31, 2024EPSTEIN, JONATHAN A.reporter.nih.gov
Hematopoietic stem and progenitor cell regulation for enhanced clinical efficacyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,911,609August 1, 2015July 31, 2028KAPUR, REUBENreporter.nih.gov
Study of cell-type specific Alzheimer's disease genetic variants using a novel bioengineered model of iPSC-derived neural tissueNIHNational Institute on Aging2021 to 2024$3,903,556May 1, 2020April 30, 2026TESCO, GIUSEPPINAreporter.nih.gov
Characterizing Wnt Signaling Pathways in Axon GuidanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,896,283June 15, 2023May 31, 2026ZOU, YIMINreporter.nih.gov
Multicellular Mechanisms Driving Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,884,176May 17, 2021April 30, 2029CAVALLI, VALERIAreporter.nih.gov
Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated CardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,869,226May 1, 2018May 31, 2027WU, JOSEPH C.reporter.nih.gov
Multi-center Evaluation of the Threat of Established and Emerging Respiratory Viral Infections in Pediatric Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,866,357September 17, 2021August 31, 2027STEINBACH, WILLIAM Jreporter.nih.gov
T cells in the aging brainNIHNational Institute on Aging2021 to 2025$3,850,998June 15, 2021March 31, 2027BRUNET, ANNEreporter.nih.gov
Understanding Skin Tissue Repair in Live MammalsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,829,886March 1, 2018August 31, 2027GRECO, VALENTINAreporter.nih.gov
The role of hypoxia in venous neointimal hyperplasia in hemodialysis graftsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,815,411February 1, 2010April 30, 2028MISRA, SANJAYreporter.nih.gov
Vascular Growth and RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,813,801February 7, 2018August 31, 2024IRUELA-ARISPE, M. LUISAreporter.nih.gov
Cell competition in pulmonary fibrosis and ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,796,920August 20, 2022July 31, 2029DE LANGHE, STIJN PIET JOHANreporter.nih.gov
A two-pronged approach to generating novel models of photoreceptor degeneration for regenerative cell therapyNIHNational Eye Institute2021 to 2024$3,781,701September 30, 2021July 31, 2026FU, YINGBINreporter.nih.gov
Modulating Glial Fate and Function in Development and DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,751,910May 1, 2020April 30, 2028TESAR, PAUL JOSEPHreporter.nih.gov
Live Imaging of Skin RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,713,235September 7, 2012August 31, 2027GRECO, VALENTINAreporter.nih.gov
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,710,340September 1, 2023August 31, 2028WEISS, MITCHELL Jreporter.nih.gov
Elucidating the Biological Differences Between Distinct Fibrillar and Non-Fibrillar Alpha-Synuclein Inclusions in Human Stem-Cell ModelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,706,946July 1, 2020April 30, 2026KHURANA, VIKRAMreporter.nih.gov
Stimulation of novel spinal respiratory circuit to restore breathing in ventilator-dependent patients with SCI.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,702,825August 1, 2021December 31, 2027LU, DANIELreporter.nih.gov
Harnessing the therapeutic potential of neural crest cells by manipulating the primary ciliumNIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,694,614September 14, 2017June 30, 2025BRUGMANN, SAMANTHA Areporter.nih.gov
THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATIONNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,689,371July 16, 2012May 31, 2027BAKER, OLGA JULIANAreporter.nih.gov
Optimizing Hematopoietic Stem Cell Transplantation For The Treatment Of Hematological MalignanciesNIHNational Cancer Institute2021 to 2025$3,687,540September 7, 2017June 30, 2032DIPERSIO, JOHN F.reporter.nih.gov
Tissue-engineered trachea composites for long-segment airway replacementNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,672,010July 16, 2021June 30, 2027CHIANG, TENDYreporter.nih.gov
Regulation of cell growth and proliferationNIHNational Institute of General Medical Sciences2021 to 2025$3,670,469May 1, 2021April 30, 2027EDGAR, BRUCE ALEXANDERreporter.nih.gov
Targeting Cell-Type Specific Disease Phenotypes to Promote CNS RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,654,519August 1, 2023April 30, 2028LEE, JAE Kreporter.nih.gov
Improving Tissue Engineered Vascular Graft Performance via Computational ModelingNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,638,571January 1, 2018March 31, 2027BREUER, CHRISTOPHER KANEreporter.nih.gov
Bioengineering Center for Regeneration and Formation of Tissues (SC BioCRAFT)NIHNational Institute of General Medical Sciences2021 to 2023$3,635,427July 1, 2019June 30, 2025VYAVAHARE, NAREN Rreporter.nih.gov
Oocyte polarity and BMP-mediated dorsoventral patterningNIHNational Institute of General Medical Sciences2021 to 2025$3,633,141June 1, 2019May 31, 2029MULLINS, MARY C.reporter.nih.gov
Intranasal Treatment of Stem Cell-derived Extracellular Vesicles for Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$3,620,000August 1, 2022July 31, 2027SHETTY, ASHOK Kreporter.nih.gov
HCMV-induced innate-like CD8 T cells and allogeneic HCT outcomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,601,018April 9, 2021March 31, 2027HSU, KATHARINE Creporter.nih.gov
New technologies to identify molecular regulators of the human hippocampus neurogenic niche in healthy aging and Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$3,598,243May 15, 2022February 28, 2027DUPONT, MAURA BOLDRINIreporter.nih.gov
Human iPSC Model to Elucidate Metabolic Interplay in Diabetic CardimyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,569,593April 1, 2019April 30, 2027WU, JOSEPH C.reporter.nih.gov
Reprogramming of mature SMCs to vascular progenitor cells: Focus on Vascular FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,548,396January 18, 2019June 30, 2027WEISER-EVANS, MARY CMreporter.nih.gov
Ocular Immune Regulation by Mesenchymal Stem CellsNIHNational Eye Institute2021 to 2025$3,542,949April 1, 2015September 14, 2028CHAUHAN, SUNIL Kreporter.nih.gov
Molecular Mechanisms Controlling Lymphatic Vascular Function in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,522,987July 5, 2016May 31, 2027CHEN, HONGreporter.nih.gov
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical TrialNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,521,212September 15, 2020August 31, 2025BERGER, STUARTreporter.nih.gov
Mechanisms of Alveolar Homeostasis, Injury, Regeneration, and FibrosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,471,063March 1, 2022February 28, 2029ZEMANS, RACHEL LYNNEreporter.nih.gov
Intensive tailored exercise training with NAD+ precursor supplementation to improve muscle mass and fitness in adolescent and young adult survivors of hematopoietic stem cell transplantationNIHNational Cancer Institute2021 to 2025$3,469,202September 1, 2021August 31, 2027MOSTOUFI-MOAB, SOGOLreporter.nih.gov
Molecular genetics of axon and synapse development and maintenanceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,460,604May 1, 2022April 30, 2030JIN, YISHIreporter.nih.gov
Randomized trial of viral specific T-cell infusion to prevent viral infection after hematopoietic stem cell transplant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,457,708July 1, 2021April 30, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Immunobiology of Lung Injury and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,455,443January 21, 2019December 31, 2024MOORE, BETHANY B.reporter.nih.gov
Leveraging zebrafish models to dissect and enhance heart regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,454,465May 15, 2020December 31, 2024POSS, KENNETH Dreporter.nih.gov
Biomaterials-directed regenerative immunotherapiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$3,438,750September 25, 2019August 31, 2025ELISSEEFF, JENNIFER Hreporter.nih.gov
The Impact of the Bone Marrow Niche's Immune Privilege on Psoriatic ArthritisNIHNational Institute of Allergy and Infectious Diseases2025$3,406,145August 8, 2025July 31, 2029FUJISAKI, JOJIreporter.nih.gov
Remediating fibrosis for salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,392,837April 1, 2019March 31, 2029LARSEN, MELINDAreporter.nih.gov
Developmental origins and homeostatic mechanisms underlying adult phenotypesNIHNational Institute of General Medical Sciences2021 to 2025$3,384,344May 1, 2017April 30, 2027PARICHY, DAVID Mreporter.nih.gov
Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vectorNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,369,470July 7, 2016December 31, 2029WILLIAMS, DAVID Areporter.nih.gov
Cochlear synaptopathy in noise-induced and age-related hearing loss: mechanisms and treatmentsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,352,414April 1, 1982February 29, 2028LIBERMAN, M. CHARLESreporter.nih.gov
Cellular and molecular mechanisms underlying DDX3X syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,350,844January 1, 2021November 30, 2026SILVER, DEBRA L.reporter.nih.gov
Dystrophin ReplacementNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,349,499April 1, 1991April 30, 2026CHAMBERLAIN, JEFFREY Sreporter.nih.gov
Regulation of Progenitor Cell Plasticity in Lung Development and Disease-RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,331,553July 1, 2023June 30, 2030CARDOSO, WELLINGTON V.reporter.nih.gov
Hydrogels for human beta cell survival, function and evasion of immune rejectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,331,035September 15, 2022May 31, 2027GARCIA, ANDRES Jreporter.nih.gov
The Primate Corticospinal Connectome and TranscriptomeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,321,910September 15, 2017May 31, 2026TUSZYNSKI, MARK H.reporter.nih.gov
Leveraging 3D bioprinted organoid constructs to pattern and model human brain developmentNIHNational Institute of Mental Health2021 to 2025$3,321,612April 1, 2021January 31, 2026SLOAN, STEVEN Areporter.nih.gov
Genetic control of developmental timingNIHNational Institute of General Medical Sciences2021 to 2025$3,305,251May 1, 2019January 31, 2030AMBROS, VICTORreporter.nih.gov
Angiogenic growth factor delivery for vascular regeneration in critical limb ischemia using acoustically-responsive scaffoldsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,303,433December 15, 2017November 30, 2027FABIILLI, MARIO LEONARDOreporter.nih.gov
Vascular Dysfunction in Myocardial Ischemia and Metabolic SyndromeNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,258,608April 1, 2016June 30, 2027SELLKE, FRANK Wreporter.nih.gov
Identification of enteric Juvenile Protective Factors and their role in stimulating neurogenesis in the adult and ageing Enteric Nervous SystemNIHNational Institute on Aging2021 to 2025$3,254,354January 15, 2021December 31, 2026GOFF, LOYAL ANDREWreporter.nih.gov
Genetic and Molecular Dissection of Wnt Pathway ActivationNIHNational Institute of General Medical Sciences2021 to 2025$3,246,880June 1, 2020July 31, 2030AHMED, YASMATHreporter.nih.gov
A spatial view of hematopoietic regeneration dynamics in the bone marrowNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$3,245,428September 15, 2024July 31, 2029LU, RONGreporter.nih.gov
Genetically Diverse Mouse Embryonic Stem Cells: A Platform for Cellular Systems GeneticsNIHOffice of the Director, National Institutes of Health2021 to 2024$3,241,681March 1, 2021May 31, 2025REINHOLDT, LAURA Greporter.nih.gov
Telemetric Regenerative Bandage for Accelerating Wound HealingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,240,738September 24, 2021July 31, 2027AMEER, GUILLERMO ANTONIOreporter.nih.gov
Mechanisms of specification, quiescence, and regeneration of primordial germ cellsNIHNational Institute of General Medical Sciences2021 to 2025$3,240,052June 1, 2021September 30, 2026WESSEL, GARY Mreporter.nih.gov
Developing second generation SCID pig models: filling the gaps to improve translation of therapeutics in regenerative medicineNIHOffice of the Director, National Institutes of Health2021 to 2025$3,219,338February 15, 2020July 31, 2029TUGGLE, CHRISTOPHERreporter.nih.gov
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,218,917August 15, 2015June 30, 2026JENQ, ROBERTreporter.nih.gov
The epigenetic regulation of inflammation in tissue repair and vascular diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,217,378July 1, 2023June 30, 2030GALLAGHER, KATHERINE ANNreporter.nih.gov
Regulation of Epidermal Development and Differentiation-RenewalNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,204,420January 1, 1983May 31, 2026FUCHS, ELAINEreporter.nih.gov
Reprogramming and Directed Differentiation of Skeletal Muscle Cells from hPSCsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,204,262September 20, 2013June 30, 2028PYLE, APRIL Dreporter.nih.gov
Cell specific delivery of novel therapies to enhance glomerular regeneration and repairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,199,320September 1, 2020May 31, 2025SHANKLAND, STUART JAMESreporter.nih.gov
Technology-Enabled Activation of Skin Cancer Screening for Hematopoietic Cell Transplantation Survivors and their Primary Care ProvidersNIHNational Cancer Institute2021 to 2024$3,192,137April 1, 2020March 31, 2026ARMENIAN, SAROreporter.nih.gov
Human Umbilical Cord as a Regenerative Meningeal Patch to Prevent Tethering and Improve Neurological Function Following In-Utero Spina Bifida RepairNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,190,303April 1, 2021February 28, 2027PAPANNA, RAMESHAreporter.nih.gov
Regulation of Growth and MorphogenesisNIHNational Institute of General Medical Sciences2021 to 2025$3,183,036May 1, 2019April 30, 2029IRVINE, KENNETH Dreporter.nih.gov
Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza responseNIHNational Institute of Allergy and Infectious Diseases2025$3,182,827August 19, 2025July 31, 2029OH, JULIAreporter.nih.gov
Tissue Engineering and RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,182,470July 1, 1976June 30, 2027KOHN, DAVID H.reporter.nih.gov
Developing preclinical xenograft models in zebrafish.NIHOffice of the Director, National Institutes of Health2022 to 2025$3,178,512March 1, 2022February 28, 2026LANGENAU, DAVID MICHAELreporter.nih.gov
Autologous BM-MSCs and Islet Co-transplantation to Enhance Islet Survival and Function in TP-IAT PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,169,762August 24, 2021May 31, 2027WANG, HONGJUNreporter.nih.gov
Hematopoietic Stem Cell And Cord Blood TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,169,146September 30, 2005May 31, 2030PETERSDORF, EFFIE Wreporter.nih.gov
Next Generation Therapies for Fertility Preservation in Male Cancer PatientsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,165,939May 15, 2020April 30, 2025ORWIG, KYLE EDWINreporter.nih.gov
Cellular Reinnervation Therapy for Vocal Fold ParalysisNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,161,418August 4, 2021May 31, 2027HALUM, STACEY L.reporter.nih.gov
Ex Vivo Generation of Functional Kidney Tissues for TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,161,308September 1, 2020May 14, 2025LEWIS, JENNIFER A.reporter.nih.gov
Engineering Vascularized Cardiac MuscleNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,149,452July 1, 2005March 31, 2027VUNJAK-NOVAKOVIC, GORDANAreporter.nih.gov
Supply and Demand: Oxygen and Workload Regulate Cardiomyocyte ProliferationNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,145,077February 15, 2023February 28, 2025SADEK, HESHAMreporter.nih.gov
Molecular control of cardiac regenerative potentialNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,142,578December 1, 2017December 31, 2026HUANG, GUOreporter.nih.gov
Harnessing Novel Human Endocrine Progenitor Biology for Enhanced Generation of Beta Cells from Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,140,632September 1, 2025August 31, 2029SNEDDON, JULIE BETHreporter.nih.gov
Preclinical Assessment of a Compliance Matched Biopolymer Vascular GraftNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,139,611December 15, 2021November 30, 2026VANDE GEEST, JONATHAN PIETERreporter.nih.gov
Cellular Therapy for Type 1 Diabetes using Mesenchymal Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,134,067June 1, 2019March 31, 2027WANG, HONGJUNreporter.nih.gov
Modeling intestinal dysfunction in HIV infection with organoid technologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,127,465January 10, 2020December 31, 2025OTT, MELANIE MARIAreporter.nih.gov
Parametric Response Mapping (PRM) for the detection of chronic lung injury in hematopoietic cell transplant recipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,121,383August 15, 2022July 31, 2026YANIK, GREGORY Areporter.nih.gov
Gvl mHA Specific T Cell Responses Prevent AML Relapse Following Allogeneic Stem Cell Transplantation.NIHNational Cancer Institute2021 to 2025$3,119,515July 1, 2020June 30, 2027VINCENT, BENJAMIN Greporter.nih.gov
Penetrating the “Black box”: Prediction of early Bronchiolitis obliterans in Pediatric Hematopoietic Stem Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,117,523July 15, 2021April 30, 2027MYERS, KASIANIreporter.nih.gov
Neural stem cell rejuvenation through single cell pharmacogenomicsNIHNational Institute on Aging2022 to 2025$3,117,021June 15, 2022February 28, 2027BONAGUIDI, MICHAELreporter.nih.gov
Integrating TPM and PAM to examine the metabolic underpinning of neurovascular repair after strokeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,104,362September 1, 2021June 30, 2026HU, SONGreporter.nih.gov
Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,102,648August 4, 2021May 31, 2027ADAMS, PETER D.reporter.nih.gov
Engineering Injectable Microporous Hydrogels for Diabetic Wound RepairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,099,608August 2, 2021June 30, 2027GRIFFIN, DONALD RICHIERIreporter.nih.gov
Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,096,729September 12, 2022May 31, 2027GRATTONI, ALESSANDROreporter.nih.gov
Mouse and human vestibular regeneration and functionNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,090,473December 1, 2018November 30, 2028CHENG, ALAN GI-LUNreporter.nih.gov
Resolution of inflammation in healing myocardial infarctsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,081,125January 15, 2008December 31, 2026FRANGOGIANNIS, NIKOLAOS Greporter.nih.gov
Therapeutic Anti-HIV Chimeric Antigen Receptors Via Stem Cell DeliveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,081,124January 16, 2020December 31, 2024YANG, OTTO Oreporter.nih.gov
Harnessing natural stem cell-based strategies for mammalian dental renewalNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,080,448September 22, 2016June 30, 2024KLEIN, OPHIR Dreporter.nih.gov
Spinal Reflex Conditioning System for Enhancing Motor Function Recovery After Incomplete Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,077,317September 30, 2020December 31, 2026CLEMENTS, ISAAC PERRYreporter.nih.gov
Chemical and Physical Mechanisms of Wound DetectionNIHNational Institute of General Medical Sciences2021 to 2025$3,076,041May 1, 2021April 30, 2026NIETHAMMER, PHILIPP MICHAELreporter.nih.gov
Anti-inflammatory Cell Based Repair of Intervertebral Disc DegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,075,117September 1, 2021August 31, 2026CHAHINE, NADEEN O.reporter.nih.gov
BIOLOGICAL EMBEDDING OF CONTEXTUAL FACTORS IN HUMAN STEM CELLS: IMPLICATIONS FOR POPULATION HEALTH DIFFERENCESNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,074,250September 26, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Mechanism of stathmin-2-dependent axon maintenance, regeneration, and functionNIHNational Institute of Neurological Disorders and Stroke2025$3,072,075April 1, 2020March 31, 2029CLEVELAND, DON Wreporter.nih.gov
Optimizing a patient-specific regenerative larynx implant for restoration of voiceNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,070,095September 1, 2021August 31, 2027LOTT, DAVID Greporter.nih.gov
First Aid Medicine to Treat Vesicant Induced Corneal InjuryNIHNational Eye Institute2022 to 2025$3,055,554September 30, 2022August 31, 2027CHANDLER, HEATHERreporter.nih.gov
Microengineering vascularized and innervated bone-like scaffolds as an alternative to autologous bone graftsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,048,776August 1, 2021April 30, 2027BERTASSONI, LUIZ EDUARDOreporter.nih.gov
DREAM Complex Maintenance of Human Beta Cell QuiescenceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,048,223July 1, 2021May 31, 2026STEWART, ANDREW F.reporter.nih.gov
Maladaptive Plasticity in Spinal Cord Injury: Cellular MechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,505July 15, 2021June 30, 2026FERGUSON, ADAM Rreporter.nih.gov
Macrophage Depletion Therapy for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,324March 15, 2021November 30, 2025GENSEL, JOHN Creporter.nih.gov
Retinal Ganglion Cell Replacement in Clinically Relevant Models of Optic NeuropathyNIHNational Eye Institute2021 to 2022$3,026,491September 30, 2018August 31, 2024REX, TONIA Sreporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
Mitochondrial respiration as a regulator of lymphatic cell fate and therapeutic lymphangiogenesisNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,026,108July 1, 2022June 30, 2027OLIVER, GUILLERMO Creporter.nih.gov
Modeling Inner Ear Differentiation with Pluripotent Stem CellsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,024,653March 1, 2014May 31, 2029HASHINO, ERIreporter.nih.gov
Mechanisms and rescue of craniosynostosis associated with gene-environment interactionNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,011,888July 1, 2021April 30, 2027CHEN, JIANFUreporter.nih.gov
Commercialization Readiness for Bone Filler Scaffold Device to Aid in Dental Applications and ReconstructionNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,006,953September 22, 2018August 31, 2024BALLARD, SHARON Creporter.nih.gov
Generating Exogenic Organs for Transplantation without the Use of ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,005,890September 21, 2022July 31, 2027STEER, CLIFFORD JOHNreporter.nih.gov
LIVE IMAGING OF BONE REGENERATION IN ZEBRAFISHNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,005,724February 1, 2020May 31, 2030DI TALIA, STEFANOreporter.nih.gov
New BDNF Nanoparticles for Early Treatment of Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2024$2,998,661September 15, 2017August 31, 2025VITALIANO, FRANCOreporter.nih.gov
Genetic Regulation of Developmental and Regenerative GrowthNIHNational Institute of General Medical Sciences2021 to 2025$2,996,144April 1, 2017February 28, 2027HARIHARAN, ISWAR K.reporter.nih.gov
Development of a novel, regenerative therapy to reverse synapse loss in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$2,994,510June 1, 2023May 31, 2025VANDERKLISH, PETER Wreporter.nih.gov
Salivary gland ionocyte organization and function during homeostasis, repair, and diseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,994,334August 18, 2021May 31, 2027MAKARENKOVA, HELEN P.reporter.nih.gov
Adhesion G Protein-Coupled Receptors in CNS Development and RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,987,194September 30, 2015May 31, 2027PIAO, XIANHUAreporter.nih.gov
Stem Cell and Transplantation BiologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,984,057August 1, 2015July 31, 2028STIREWALT, DEREK Lreporter.nih.gov
Genetically-engineered stem cells for self-regulating arthritis therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,983,611April 1, 2022March 31, 2027GUILAK, FARSHIDreporter.nih.gov
Integration and functionality of retinal organoid transplantsNIHNational Eye Institute2021 to 2025$2,971,351May 1, 2021March 31, 2027SEILER, MAGDALENE Jreporter.nih.gov
Programming cellular behavior by mechanical forcesNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$2,968,476September 9, 2024August 31, 2029BERRO, JULIENreporter.nih.gov
Photoabsorbing bioinks for expanding 3D printed human liver in situNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,967,973September 21, 2021May 31, 2026STEVENS, KELLY Rreporter.nih.gov
Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,966,978December 1, 2021November 30, 2026CHENG, GUANG-SHINGreporter.nih.gov
MIDAS: MIcroangiopathy, endothelial Damage in Adults undergoing Stem cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,957,506August 20, 2020July 31, 2026VASU, SUMITHIRAreporter.nih.gov
Preclinical studies of pluripotent stem cell-derived myogenic progenitors in non-human primatesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,948,443August 6, 2021December 31, 2026PERLINGEIRO, RITA C. R.reporter.nih.gov
Ethanol Effects on the Transcriptional Regulatory Network in Liver RegenerationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,943,903September 30, 2009July 31, 2027SRIVASTAVA, ANKITAreporter.nih.gov
Exosomes and the Immune Response in Allograft Outcomes in Pediatric Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,938,841May 10, 2022June 30, 2024KRAMS, SHERI M.reporter.nih.gov
Single-cell analysis to promote kidney repairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,938,759September 1, 2020May 31, 2025HUMPHREYS, BENJAMIN D.reporter.nih.gov
A molecular and physical mechanism for growing and branching the intestinal villusNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,934,732September 15, 2020November 30, 2028GARTNER, ZEV JORDANreporter.nih.gov
Infusible Extracellular Matrix for Treating Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,929,153June 10, 2022May 31, 2027CHRISTMAN, KAREN Lreporter.nih.gov
Immunomodulation of juvenile femoral head osteonecrosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,923,511July 1, 2021March 31, 2027KIM, HARRY K.W.reporter.nih.gov
Mechanistic evaluation of the role of circadian rhythms in acute lung injury and subsequent recoveryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,922,801September 20, 2021August 31, 2027SENGUPTA, SHAONreporter.nih.gov
Specification, Molecular Control and Niche Functions of the Hair Follicle MesenchymeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,922,092September 15, 2016August 31, 2026RENDL, MICHAELreporter.nih.gov
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,919,684April 1, 2021March 31, 2026CULLEN, DANIEL KACYreporter.nih.gov
Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,918,081August 15, 2021July 31, 2026LI, PULINreporter.nih.gov
Dendrite morphogenesis, function and regenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,908,475December 1, 2016November 30, 2024JAN, YUH NUNGreporter.nih.gov
iPSC-Derived Vascularized Human Lung Organoids and Interaction Between Lung Endothelial Cells and Alveolar Epithelial CellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,907,792August 1, 2022May 31, 2027REHMAN, JALEESreporter.nih.gov
Epithelial-Mesenchymal Interactions in Fibrosis ResolutionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,901,344August 6, 2009April 30, 2027TSCHUMPERLIN, DANIEL J.reporter.nih.gov
Protection and restoration of cochlear synapses from noise-induced synaptopathy in male and female miceNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,899,116June 1, 2021May 31, 2027GREEN, STEVEN Hreporter.nih.gov
Retinal disease models for translational photoreceptor replacementNIHNational Eye Institute2021 to 2022$2,898,123September 30, 2018May 31, 2025WOLFE, JOHN Hreporter.nih.gov
Preclinical Toxicology Study of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,885,957April 1, 2022August 31, 2027SUN, MIAOreporter.nih.gov
Using donor dendritic cells to optimize GvHD and GvL in allogeneic stem cell transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,867,908June 1, 2020May 31, 2026WALLER, EDMUND Kreporter.nih.gov
WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,862,721September 10, 2021August 31, 2026LEE, BRENDANreporter.nih.gov
Elucidating the Molecular Mechanisms Underlying LYST-mediated Tissue Engineered Vascular Graft StenosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,861,908April 1, 2021March 31, 2026BREUER, CHRISTOPHER KANEreporter.nih.gov
Phenotyping Genetic Disorders of Hepatic Lipid and Lipoprotein Metabolism in Cells, Mice, and MenNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,861,646January 1, 2017December 31, 2024GINSBERG, HENRY Nreporter.nih.gov
Quantitative Multiparametric MRI to Assess the Effect of Stem Cell Therapy on Chronic Low Back PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,858,064August 1, 2014July 31, 2025LI, DEBIAOreporter.nih.gov
Molecular regulation of native hematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,856,222February 15, 2016December 31, 2025CAMARGO, FERNANDOreporter.nih.gov
Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment Following Hematopoietic Stem Cell TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,855,157May 1, 2020April 30, 2026KELLER, MICHAEL DANIELreporter.nih.gov
New upstream targets for HIF-1a-mediated regeneration in young and aged animalsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,854,411May 1, 2011May 31, 2027HEBER-KATZ, ELLEN S.reporter.nih.gov
Wnt signaling in hematopoietic developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,849,578January 1, 2017June 30, 2025WILLERT, KARL Hreporter.nih.gov
Beyond the Barrier: Alveolar Epithelial Cell Biology in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,844,000August 15, 2021June 30, 2025BOROK, ZEAreporter.nih.gov
HEMANGIOBLAST DEVELOPMENT AND REGULATIONNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,843,107August 1, 1996May 31, 2026CHOI, KYUNGHEEreporter.nih.gov
Efficacy of a Mindfulness-Based Stress Management Program for Allogeneic HCT CaregiversNIHNational Cancer Institute2021 to 2025$2,839,105April 1, 2021March 31, 2027VINCI, CHRISTINEreporter.nih.gov
Decoding LRH-1 Activity in Gut Regeneration and DifferentiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,837,160June 14, 2021April 30, 2026BAYRER, JAMESreporter.nih.gov
Developing gene therapy strategies to treat alpha thalassemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,821,947January 1, 2022December 31, 2025MACKENZIE, TIPPIreporter.nih.gov
Tailoring of cellular mechanical microenvironments to rescue age-related impairments in bone regenerationNIHNational Institute on Aging2022 to 2025$2,821,555September 30, 2022May 31, 2027MORGAN, ELISE Freporter.nih.gov
Developing Cone-Dominant Retinal Disease Models as a Resource for Translational Vision ResearchNIHNational Eye Institute2021 to 2022$2,820,106September 30, 2018August 31, 2022CARROLL, JOSEPHreporter.nih.gov
Genome editing of human pancreatic islets to withstand ischemic injuries and promote immune evasionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,817,305July 1, 2022April 30, 2027TANG, QIZHIreporter.nih.gov
Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,816,253July 1, 2016November 30, 2026ZHANG, JIANYIreporter.nih.gov
Mechanisms of HIV-associated epithelialintestinal stem cell (ISC) dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,811,833July 1, 2020June 30, 2025KWON, DOUGLASreporter.nih.gov
The role of the intestinal microbiome in cancer immunotherapyNIHNational Cancer Institute2023 to 2025$2,811,009August 1, 2023July 31, 2030VAN DEN BRINK, MARCEL R Mreporter.nih.gov
Prdm3/16 Regulate Chromatin Accessibility to Determine Alveolar MaturationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,805,992July 1, 2022June 30, 2027WHITSETT, JEFFREY Areporter.nih.gov
Biomaterials Strategies to Promote Functional Recovery After Ischemic StrokeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,801,281March 1, 2020June 30, 2030SEGURA, TATIANAreporter.nih.gov
Cellular and molecular analysis of B lymphocyte development and selectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,800,489June 15, 2014April 30, 2030PEREIRA, JOAOreporter.nih.gov
Impact of particle and ozone inhalation co-exposure on alveolar epithelial regenerationNIHNational Institute of Environmental Health Sciences2021 to 2024$2,799,613May 1, 2020February 28, 2026HUSSAIN, SALIKreporter.nih.gov
Neural Circuits, Kinetics and Energetics HTS of Human iPSC-Neurons, -Microglia, and -Astrocytes: AI-Enabled Platform for Target ID, and Drug Discovery and Toxicity (e.g., Cancer Chemo & HIV ARTs)NIHNational Institute of Mental Health2023 to 2025$2,798,182September 1, 2023August 31, 2026PRICE, JEFFREY H.reporter.nih.gov
The Role of Renal Interstitium in Kidney DevelopmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,791,644July 15, 2021May 31, 2025CARROLL, THOMAS JOSEPHreporter.nih.gov
Polymer Scaffolds for Mandibular Condyle Cartilage RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,788,930December 1, 2020November 30, 2025ALMARZA, ALEJANDRO JOSEreporter.nih.gov
Cardiovascular reserve capacity in survivors of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,785,889February 1, 2020January 31, 2026ARMENIAN, SAROreporter.nih.gov
Bioactive Scaffold for TMJ Disc Regeneration by Endogenous Stem/Progenitor CellsNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,782,994August 11, 2020July 31, 2026LEE, CHANG HUNreporter.nih.gov
Targeting vascular dysfunction to promote lung repair and fibrosis resolutionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,782,716March 5, 2022February 28, 2027LIGRESTI, GIOVANNIreporter.nih.gov
Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,778,087July 1, 2022April 30, 2027GRATTONI, ALESSANDROreporter.nih.gov
Intraosseous delivery of lentiviral vectors for hemophilia A gene therapyNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,777,901August 15, 2016June 30, 2026MIAO, CAROL Hreporter.nih.gov
Mechanisms and Impact of Pregnancy-Induced Adaptations in Pelvic Floor MusclesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,761,892August 1, 2017June 30, 2026ALPERIN, MARIANNAreporter.nih.gov
Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,760,413May 1, 2020April 30, 2026YANG, BOreporter.nih.gov
Computational and Experimental Modeling of Cardiomyocyte ProliferationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,757,722January 1, 2022December 31, 2026SAUCERMAN, JEFFREY J.reporter.nih.gov
Functional Biointegration of Bioengineered Salivary Tissues in Irradiated Animal ModelsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,754,807September 19, 2022June 30, 2027FARACH-CARSON, MARY Creporter.nih.gov
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivorsNIHNational Cancer Institute2021 to 2025$2,750,972July 12, 2021June 30, 2027NGEN, ETHEL JOSOreporter.nih.gov
In vivo HSC gene therapy using a multi-modular HDAd vector for HIV cureNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,743,808January 10, 2023December 31, 2027LIEBER, ANDRE MICHAELreporter.nih.gov
Cadherin-Dependent Regulation of Satellite Cell FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,741,976July 15, 2016June 30, 2027KRAUSS, ROBERT S.reporter.nih.gov
Determining how chronic ETOH influences the regenerative activities of hepatocyte subpopulationsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,741,497August 1, 2021April 30, 2026ZHU, HAOreporter.nih.gov
Protection of Ischemic MyocardiumNIHNational Heart, Lung, and Blood Institute2021$2,741,275December 1, 2004August 31, 2023BOLLI, ROBERTOreporter.nih.gov
Neural activity-dependent modulation of cortical microvascular restorationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,739,026March 15, 2021December 31, 2025XU, XIANGMINreporter.nih.gov
Human Induced Pluripotent Stem Cells for Cardiovascular Disease ModelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,737,027May 1, 2012March 31, 2027WU, JOSEPH C.reporter.nih.gov
Angiogenic and anti-microbial supports for pulp regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,731,189February 23, 2022August 15, 2025KUMAR, VIVEKreporter.nih.gov
Conformal Total Body and Marrow Irradiation for LeukemiaNIHNational Cancer Institute2021 to 2024$2,727,228September 13, 2011December 31, 2025HUI, SUSANTA Kreporter.nih.gov
In Vitro Human Tissue-Engineered Blood Vessel Disease Model of ProgeriaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,720,700August 1, 2017April 30, 2027TRUSKEY, GEORGE Areporter.nih.gov
Systems Genetics of Bone RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,717,663April 15, 2022January 31, 2027FARBER, CHARLES Rreporter.nih.gov
Neutralizing the degenerate disc microenvironment to enhance the efficacy of therapeutic stem cellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,717,504February 1, 2021December 31, 2026SMITH, LACHLAN JAMESreporter.nih.gov
New roles of endothelial regrowth in ischemic tissue recovery and regenerationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,697,119April 1, 2022March 31, 2027KUME, TSUTOMUreporter.nih.gov
Epigenetic Profiling of circulating cell-free DNA for the Monitoring of Graft-Versus-Host Disease after Hematopoietic Cell TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,694,538January 13, 2020December 31, 2025DE VLAMINCK, IWIJNreporter.nih.gov
Emergency Myelopoiesis in the Pathogenesis of Myeloid MalignanciesNIHNational Cancer Institute2021 to 2025$2,690,224August 1, 2021July 31, 2027PASSEGUE, EMMANUELLEreporter.nih.gov
Clinical Significance of MHC Haplotypes in HCTNIHNational Cancer Institute2021 to 2025$2,687,420March 1, 2003August 31, 2028PETERSDORF, EFFIE Wreporter.nih.gov
Enhancing Innate Immune Reconstitution Post Allogeneic HSCT.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,685,463September 1, 2021June 30, 2025SERODY, JONATHAN S.reporter.nih.gov
Implementation of an interventional, risk-adapted clinical trial for children with newly diagnosed juvenile myelomonocytic leukemia.NIHNational Cancer Institute2022 to 2025$2,677,641August 1, 2022July 31, 2027STIEGLITZ, ELLIOTreporter.nih.gov
Metabolic Control of Stemness in lung epithelial progenitors by FAM13ANIHNational Heart, Lung, and Blood Institute2021 to 2024$2,676,003April 1, 2015November 30, 2025ZHOU, ANNY XIAOBOreporter.nih.gov
Study of Activity-Dependent Sympathetic SproutingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,675,718May 4, 2004June 30, 2026ZHANG, JUN-MINGreporter.nih.gov
Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large MammalsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,675,195August 9, 2022June 30, 2027ZHU, WUQIANGreporter.nih.gov
Immuno-Isolating capsule for delivery of cell-based therapy for restoration of ovarian endocrine function in an animal modelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,674,237August 15, 2022May 31, 2027SHIKANOV, ARIELLAreporter.nih.gov
Corneal Epithelial-Stromal Interactions During Regeneration and FibrosisNIHNational Eye Institute2021 to 2025$2,667,355December 1, 1984August 31, 2027CIOLINO, JOSEPH B.reporter.nih.gov
Rehabilitation from Spinal Cord Injury Using Targeted, Activity-Dependent Intraspinal StimulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,662,265August 15, 2021July 31, 2026PERLMUTTER, STEVE Ireporter.nih.gov
Ceramide-Induced Destruction in EmphysemaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,661,589July 1, 2006April 30, 2025PETRACHE, IRINAreporter.nih.gov
Negative regulators of endothelial regeneration in aging lungs and ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,661,375June 1, 2022March 31, 2026ZHAO, YOU-YANGreporter.nih.gov
Targeted Degradation of Extracellular Proteins to Enhance Brain PlasticityNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,660,000September 12, 2024August 31, 2029ALLEN, NICOLA Jreporter.nih.gov
Epigenetic Regulation of Skin Regional SpecificityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,657,118May 1, 2002March 31, 2028CHUONG, CHENG-MINGreporter.nih.gov
Antimicrobial dermal matrices to promote infection free wound closure in DTU-DFUs.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$2,649,424September 1, 2023August 31, 2025MEHTA, MANAVreporter.nih.gov
Regulation of Skeletal progenitor cells in Osteogenesis ImperfectaNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,636,174July 13, 2022April 30, 2027PARK, DONGSUreporter.nih.gov
Stress and Human Stem/Progenitor Cells: Biobehavioral MechanismsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,635,227August 15, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Augmenting Implanted Neuroprosthetics with Targeted Health Monitoring for Spinal Cord Injury - the LIFELINENIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,632,178July 1, 2021March 31, 2026KILGORE, KEVIN L.reporter.nih.gov
Psychosocial Stress Effects on Regenerative Medicine Therapies for Lower Urinary Tract Disorders in Nonhuman PrimatesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,630,241April 1, 2020March 31, 2026SHIVELY, CAROL A.reporter.nih.gov
Clinically Applicable Orofacial Cleft Reconstruction Using Structural, Compositional Biomimetic Bone ScaffoldsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,621,884August 1, 2022July 31, 2027LEE, SANG JINreporter.nih.gov
Defining Characteristics of Cortical Progenitor Cells over Time in Mouse and HumanNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,620,540December 15, 2016November 30, 2025TEMPLE, SALLYreporter.nih.gov
Biomechanical Forces and the Enteric Nervous System: Advancing the Development and Function of Tissue-Engineered IntestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,618,975September 8, 2025September 7, 2029SPEER, ALLISON LEIGHreporter.nih.gov
In Vivo Hematopoietic Stem Cell Gene Therapy of Beta-Thalassemia and Sickle Cell DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,618,613June 1, 2016July 31, 2025LIEBER, ANDRE MICHAELreporter.nih.gov
Bioresorbable Zinc Staples for Anastomoses in the Digestive TractNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,616,912February 3, 2022January 31, 2027ZHU, DONGHUIreporter.nih.gov
Regenerative pathways in the avian cochleaNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,615,111February 10, 2022January 31, 2027HELLER, STEFANreporter.nih.gov
Synthetic gene sensors and effectors to redirect organoid developmentNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,608,452May 1, 2021July 31, 2025WEISS, RONreporter.nih.gov
Development of 211Astatine-Conjugated Anti-CD45 Antibody-Based Conditioning for Hematopoietic Stem Cell Gene Therapy and EditingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,608,434May 15, 2020April 30, 2026WALTER, ROLAND BRUNOreporter.nih.gov
Translational Nonhuman Primate Regenerative Medicine and Gene Therapy/Genome Editing Resource ProgramNIHOffice of the Director, National Institutes of Health2023 to 2025$2,607,543December 1, 2022November 30, 2026TARANTAL, ALICE Freporter.nih.gov
Intravital analysis of hematopoietic stem cells in their bone marrow niche - Resubmission - 1NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,607,213September 20, 2021August 31, 2025REIZIS, BORISreporter.nih.gov
Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner earNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,603,881February 1, 2016June 30, 2027XU, PIN-XIANreporter.nih.gov
NATIONAL BIOREPOSITORY OF LUNG DISEASE-SPECIFIC HUMAN INDUCED PLURIPOTENT STEM CELLS:THE PURPOSE OF THIS RESOURCE IS TO BUILD AND SUPPORT A CRITICALNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,600,000May 1, 2020April 30, 2025N/A, N/Areporter.nih.gov
Genetic Regulatory Network in Craniofacial DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,599,984March 12, 2025January 31, 2030HSU, WEIreporter.nih.gov
The Neurospan Bridge: A Device for Peripheral Nerve RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,594,464March 15, 2023August 31, 2027KOFFLER, YACOVreporter.nih.gov
Macrophage Phenotypes and Tissue RepairNIHNational Institute of General Medical Sciences2021 to 2025$2,593,825May 1, 2020March 31, 2030KOH, TIMOTHY Jreporter.nih.gov
Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,591,324March 1, 2021February 28, 2027SHIN, SU RYONreporter.nih.gov
ETS-family Transcription Factor Mediated Control of Pulmonary Inflammation Induced by Influenza VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,590,407February 1, 2019October 31, 2028HEATON, NICHOLAS Sreporter.nih.gov
Tissue Patterning in living skin and organ explantsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,589,841September 1, 2025August 31, 2030CHUONG, CHENG-MINGreporter.nih.gov
An Interneuron-based Cell Therapy for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,589,602September 1, 2010March 31, 2027BARABAN, SCOTT Creporter.nih.gov
Understanding and Controlling Macrophage Behavior in AngiogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,588,824January 1, 2016August 31, 2025SPILLER, KARA LORRAINEreporter.nih.gov
Development of a stem-cell derived thymic cell therapy to treat patients with athymiaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,586,728April 15, 2022January 31, 2027LIM, BINGreporter.nih.gov
Heterogeneity of Satellite Cell Populations Play a Role in Improvements in PAD after Exercise TherapyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,586,669February 15, 2022January 31, 2027HANSEN, LAURA MARIEreporter.nih.gov
Synthetic organogenesis: new paradigms in reconstituting human organ development in vitroNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,586,456September 21, 2021August 31, 2026SIMUNOVIC, MIJOreporter.nih.gov
Elucidating electrical stimulation induced non-neuronal activity using emerging in vivo imaging technology and electrophysiologyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,585,973September 30, 2020June 30, 2025KOZAI, TAKASHI DANIEL YOSHIDAreporter.nih.gov
Rectifying splicing mutations in blood disorders by gene editingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,584,045December 20, 2019November 30, 2023BAUER, DANIEL EVANreporter.nih.gov
Microribbon scaffold-mediated Immunomodulation for Cranial Bone RepairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,582,020January 1, 2015May 31, 2027YANG, FANreporter.nih.gov
Leveraging immune-fibroblast interactions for biomaterial induced skin regenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,580,501September 1, 2021August 31, 2027SCUMPIA, PHILIPreporter.nih.gov
Targeted genetic engineering of B cells to induce protective antibody responses to viral pathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,577,835July 5, 2022June 30, 2027ADAIR, JENNIFER EILEENreporter.nih.gov
COATs: Collagen-mimetic peptide and therapeutic gene-modified collagens for cell-mediated healing of diabetic foot ulcersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,574,620July 30, 2021May 31, 2027SULLIVAN, MILLICENT Oreporter.nih.gov
Regeneration of the Immune System after Radiation ExposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,571,006August 18, 2022June 30, 2027GUHA, CHANDANreporter.nih.gov
Regulation of catagen regression and progenitor pruning by the dermal sheathNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,565,274July 1, 2021June 30, 2026RENDL, MICHAELreporter.nih.gov
Bioinspired Mechanically Stiff Hydrogels for Osteochondral Tissue RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,563,338July 25, 2016March 31, 2027BRYANT, STEPHANIE Jreporter.nih.gov
The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,563,053August 1, 2020July 31, 2025HUARD, JOHNNYreporter.nih.gov
Mechanisms for Regenerative Healing in Intervertebral DiscsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,560,545January 15, 2022December 31, 2026IATRIDIS, JAMES C.reporter.nih.gov
Using 3D Nonwovens Fabrication to Engineer Region-Specific Extracellular Matrix Structure and Bioactivity of the Knee MeniscusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,558,913July 1, 2021June 30, 2027FISHER, MATTHEW Breporter.nih.gov
Vascular networks genetically engineered for protein drug deliveryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,552,882August 15, 2015April 30, 2026MELERO-MARTIN, JUAN Mreporter.nih.gov
Manipulation of Host Tissue to Induce a Hierarchical MicrovasculatureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,550,390May 1, 2023April 30, 2027SHEIKHI, AMIRreporter.nih.gov
A first in human clinical study of TT101, a synthetic immunomodulatory material to build new functional tissue over exposed bone as a one time treatment for diabetic limb preservation patientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$2,549,496September 15, 2021August 31, 2024DESHAYES, STEPHANIEreporter.nih.gov
Phase1/2a Clinical Trial of RPESC-derived RPE Transplantation as Therapy for Non-exudative Age-related Macular DegenerationNIHNational Eye Institute2021 to 2024$2,549,156September 30, 2020September 29, 2025STERN, JEFFREY Hreporter.nih.gov
Roles of Noncoding RNA in Bone RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,547,514March 1, 2016August 31, 2025CHEN, JAKE JINKUNreporter.nih.gov
The Molecular Regulation of Horizontal Basal Cell Activation in the Olfactory EpitheliumNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,546,159February 7, 2020January 31, 2026SCHWOB, JAMES E.reporter.nih.gov
Engineering Adaptive Immune Responses from Hydrogel Scaffolds to Promote Tissue RegenerationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,544,732March 2, 2020February 28, 2026SEGURA, TATIANAreporter.nih.gov
Intestinal tissue intrinsic mechanisms in regulation of GI GVHDNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,544,373June 13, 2022May 31, 2027REDDY, PAVANreporter.nih.gov
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,544,362December 1, 2021August 31, 2027SAYENKO, DIMITRYreporter.nih.gov
Hair Follicle Dermal Stem Cell Functions and PotentialNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,543,600July 8, 2021June 30, 2026RENDL, MICHAELreporter.nih.gov
Functional roles of lymphatics in organogenesis and tissue repairNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,543,362January 7, 2021December 31, 2025OLIVER, GUILLERMO Creporter.nih.gov
Mechanisms of Hematopoietic Stem Cell and Blood agingNIHNational Institute on Aging2021 to 2025$2,543,077September 15, 2021May 31, 2027PASSEGUE, EMMANUELLEreporter.nih.gov
The Role of Ceramides in the Intestinal Stem CellNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,539,916September 23, 2021May 31, 2026SUMMERS, SCOTT Areporter.nih.gov
Prevention of pelvic floor muscle dysfunction with extracellular matrix hydrogelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,535,698September 30, 2020June 30, 2026ALPERIN, MARIANNAreporter.nih.gov
Genetic interactions and multifactorial genetics mediate myocardial regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,532,602February 11, 2021June 30, 2026PATTERSON, MICHAELAreporter.nih.gov
Randomized study of low versus moderate dose busulfan in transplant for severe combined immunodeficiencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,529,105August 24, 2017July 31, 2024WAYNE, ALAN S.reporter.nih.gov
Improving transfusion therapy for patients with sickle cell disease with pluripotent stem cell-derived red cellsNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,528,360September 15, 2016May 31, 2025CHOU, STELLA Treporter.nih.gov
Life history of the menstruating uterusNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,527,271September 20, 2022August 31, 2027MCKINLEY, KARA LAVIDGEreporter.nih.gov
Modeling, pathogenesis and treatment of idiopathic pulmonary fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,527,128September 20, 2016May 31, 2025SNOECK, HANS-WILLEM Ereporter.nih.gov
Flexor tendon intrinsic healing and intervention strategy developmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,522,341July 1, 2021June 30, 2027ZHAO, CHUNFENGreporter.nih.gov
Pro-youthful role of Gpld1 on regenerative and cognitive function in the aged brainNIHNational Institute on Aging2022 to 2025$2,521,023May 15, 2022April 30, 2027VILLEDA, SAUL Areporter.nih.gov
Metabolomics Technologies to Advance Biomedical ResearchNIHNational Institute of General Medical Sciences2021 to 2025$2,516,384March 1, 2019March 31, 2029SIUZDAK, GARY Ereporter.nih.gov
Dysfunctional skeletal muscle communication in arsenic-promoted cardiometabolic diseaseNIHNational Institute of Environmental Health Sciences2021 to 2025$2,513,851July 23, 2021June 30, 2026BARCHOWSKY, AARONreporter.nih.gov
In vivo modelling and therapy development for stathmin-2 loss in TDP-43 proteinopathiesNIHNational Institute of Neurological Disorders and Stroke2021$2,507,311August 1, 2021July 31, 2024LAGIER-TOURENNE, CLOTILDEreporter.nih.gov
Editing Alveolar Progenitor Cells for Correction of Monogenic DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,504,499September 23, 2016May 31, 2025WHITSETT, JEFFREY Areporter.nih.gov
Role of Fbxw7-Mediated Proteasomal Degradation in Myofibers in Determining Muscle Stem Cell Pool SizeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,494,858July 1, 2020December 31, 2026SACCO, ALESSANDRAreporter.nih.gov
Defining the role of lymphatic vessels in wound healingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,493,383April 1, 2021March 31, 2027HORSLEY, VALERIEreporter.nih.gov
The role of PHF6 in the control of hematopoietic stem cell aging.NIHNational Institute on Aging2021 to 2025$2,490,000September 1, 2021May 31, 2027PALOMERO, TERESAreporter.nih.gov
MG53 function in muscle agingNIHNational Institute on Aging2022 to 2025$2,487,828September 30, 2022June 30, 2027MA, JIANJIEreporter.nih.gov
Using a SMART Design to Optimize PTSD Symptom Management Strategies Among Cancer SurvivorsNIHNational Cancer Institute2021 to 2024$2,482,100December 1, 2019November 30, 2025SMITH, SOPHIA K.reporter.nih.gov
Genetic dissection of trait variation between long-diverged mouse speciesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,481,029September 30, 2019June 30, 2025BREM, RACHEL BETHreporter.nih.gov
Osteoimmunology of Retarded Bone Regeneration in PeriodontitisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,478,353December 1, 2024July 31, 2026KAWAI, TOSHIHISAreporter.nih.gov
Trimodal Vitality Imaging of Neural Progenitor Cells in the Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,476,665August 1, 2020April 30, 2027EMELIANOV, STANISLAV Yreporter.nih.gov
Multimodality Intervention to Improve Function and Metabolism in Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,474,995August 21, 2018April 30, 2024BHASIN, SHALENDERreporter.nih.gov
Bioprintable composite materials and microfluidic tools for vocal fold restoration and repairNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,474,309January 1, 2021December 31, 2026MONGEAU, LUCreporter.nih.gov
Neurotrophins and post-infarct plasticity in cardiac sympathetic neuronsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,471,774July 15, 2009June 30, 2028HABECKER, BETH Areporter.nih.gov
Determination of Hair Cell Fate from Postnatal Cochlear Supporting CellsNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,469,452May 4, 2022April 30, 2027EDGE, ALBERTreporter.nih.gov
Lung leukocytes promote alveolar epithelial regeneration after severe injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,469,157May 1, 2020April 30, 2026ARPAIA, NICHOLASreporter.nih.gov
Hormetic ER Stress Regulation of Hematopoietic Stem Cell FunctionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,466,695July 3, 2021May 31, 2026LUCHSINGER, LARRY Lreporter.nih.gov
Regulation of endothelial cell specificationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,466,084February 15, 2021January 31, 2025PU, WILLIAM TSWENCHINGreporter.nih.gov
Engineered Granular Hydrogels for Endogenous Tissue RepairNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,464,894May 26, 2022April 30, 2027BURDICK, JASON Areporter.nih.gov
A unique strategy for reshaping the antibiotics model: chemokine-inspired therapeutics for targeting the host and pathogen to counter infections caused by multidrug-resistant bacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,464,828September 24, 2020August 31, 2025HUGHES, MOLLY Areporter.nih.gov
Mechanism of transplanted neonatal cardiac progenitor cells to repair ischemic myocardiumNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,462,741April 20, 2014August 31, 2025SCHUMACKER, PAUL Treporter.nih.gov
Deciphering multi-scale differentiation and patterning cues driving whole craniofacial joint regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,462,001September 6, 2022August 31, 2027SMEETON, JOANNA MARJORIEreporter.nih.gov
Brain lymphatic activation for craniosynostosis and Alzheimer’s diseaseNIHNational Institute of Neurological Disorders and Stroke2024$2,461,369June 1, 2024May 31, 2027CHEN, JIANFUreporter.nih.gov
Identifying pathways required for integration of kidney organoid and host epitheliaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,461,009September 1, 2020May 31, 2025DRUMMOND, IAIN A.reporter.nih.gov
An integrated human stem cell model for elucidating myocardial-endocardial interactions in cardiac development and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,460,707February 15, 2021January 31, 2027ZHAO, MINGTAOreporter.nih.gov
Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging - AD/ADRDNIHNational Institute on Aging2021 to 2023$2,458,774April 1, 2019January 31, 2025KACENA, MELISSA Areporter.nih.gov
Alveolar epithelial stress-induced polyploidization in lung injury and repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,458,344May 15, 2022April 30, 2027GOTTARDI, CARA Jreporter.nih.gov
Respiratory interneuron circuit plasticity: promoting recovery of diaphragm function after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,455,409March 1, 2013April 30, 2028LEPORE, ANGELO C.reporter.nih.gov
Characterization of Neural Stem Cells in Adult BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,454,507April 1, 1990March 31, 2026ALVAREZ-BUYLLA, ARTUROreporter.nih.gov
Pathogenesis of Airway Stem Cell Abnormalities in Obliterative BronchiolitisNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,452,366April 1, 2019January 31, 2029PAREKH, KALPAJ RAJNIKANTreporter.nih.gov
Regenerative Rehabilitation of Complex Musculoskeletal InjuriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,452,287April 1, 2016December 31, 2026GULDBERG, ROBERT Ereporter.nih.gov
Biochemistry of Leukemia Virus Core-Binding FactorNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,451,198August 10, 1993June 30, 2025SPECK, NANCYreporter.nih.gov
Emergency Myelopoiesis Pathways in the Control of Blood ProductionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,450,418April 1, 2017March 31, 2025PASSEGUE, EMMANUELLEreporter.nih.gov
Adenylate Kinase 2 Deficiency and the Failure of MyelopoiesisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,449,815April 1, 2022March 31, 2027WEINACHT, KATJA GABRIELEreporter.nih.gov
Control of GVHD by Probiotics with individual Commensal BacteriaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,448,717May 5, 2022April 30, 2027YU, XUE-ZHONGreporter.nih.gov
Metabolic reprogramming of Alveolar Type 2 cells in response to lung injuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,446,943July 1, 2022September 30, 2026GUTTENTAG, SUSAN H.reporter.nih.gov
A novel bioengineering approach to restoring permanent periodontal inflammatory bone lossNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,446,598July 1, 2023April 30, 2028JANG, HAE LINreporter.nih.gov
REGULATION OF ATROPHY-INDUCED PROGENITOR CELLS IN THE GASTRIC CORPUSNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,446,210September 11, 2012April 30, 2028MILLS, JASON Creporter.nih.gov
Tomotherapy and Hematopoietic Stem Cells for Tolerance to Kidney TransplantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,439,463August 1, 2012April 30, 2024KAUFMAN, DIXON Breporter.nih.gov
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,438,515January 5, 2021December 31, 2025HSU, KATHARINE Creporter.nih.gov
Genomic tools for massively parallel recording of signaling activity at cellular resolution in a brain-wide mannerNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,437,500September 22, 2022August 31, 2027RAJ, BUSHRAreporter.nih.gov
BMP2 Regulation of Periosteal FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,436,018August 1, 2020April 30, 2026ROSEN, VICKIreporter.nih.gov
Mechanisms that regulate erythroid differentiation of hematopoietic stem cellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,434,029July 1, 2022June 30, 2027NAKADA, DAISUKEreporter.nih.gov
Stem cells for therapeutics discovery in genetic blood disordersNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,429,809September 23, 2016May 31, 2025DALEY, GEORGE Qreporter.nih.gov
Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,428,878September 12, 2022May 31, 2026RAFII, SHAHINreporter.nih.gov
In vivo Monitoring of Neutrophil Function in Patients after Stem Cell TransplantNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,426,537February 13, 2023January 31, 2028IRIMIA, DANIELreporter.nih.gov
Allorecognition, parasitic stem cells and regeneration in a basal chordateNIHNational Institute of General Medical Sciences2021 to 2025$2,424,717January 1, 2021December 31, 2026DE TOMASO, ANTHONY Wreporter.nih.gov
Photoresponsive materials to study matricellular signaling dynamics during crypt formation and fissionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,423,541August 1, 2019April 30, 2028ANSETH, KRISTI S.reporter.nih.gov
Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,420,406August 15, 2020July 31, 2025GRAHN, PETER JONASreporter.nih.gov
Modulation of signaling from damage-associated molecular patterns to improve radiation-induced thymic dysfunctionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,418,442July 18, 2022May 31, 2027DUDAKOV, JARRODreporter.nih.gov
The role of mitochondria in hematopoietic stem cell self-renewalNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,417,109January 1, 2021December 31, 2024FILIPPI, MARIE-DOMINIQUEreporter.nih.gov
High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespanNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,415,000September 30, 2021July 31, 2027WESSELY, OLIVERreporter.nih.gov
Mathematical ecology models of host-microbiota interaction in auto microbiota transplants (auto-FMT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,414,163February 1, 2019January 31, 2024XAVIER, JOAOreporter.nih.gov
Genetic circuitry governing heart growth and repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,413,285March 1, 2022February 28, 2027HUANG, GUOreporter.nih.gov
Immunoevasive Engineered Living Blood VesselsNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,412,484August 5, 2022April 30, 2027CHAIKOF, ELLIOTreporter.nih.gov
Innate immune response signaling in cardiac injury healingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,408,533January 1, 2022December 31, 2026MOLKENTIN, JEFFERY Dreporter.nih.gov
Basal cells in airway and alveolar remodelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,407,737May 1, 2022April 30, 2026STRIPP, BARRY Rreporter.nih.gov
SMART BIOELECTRONIC IMPLANTS FOR CONTROLLED DELIVERY OF THERAPEUTIC PROTEINS IN VIVO AND ITS APPLICATION IN LONG-TERM TREATMENT OF HEMOPHILIA ANIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,406,599May 1, 2022January 31, 2026ANDERSON, DANIEL Greporter.nih.gov
Next generation anti-cancer drugdelivering cement for bone metastasis patientsNIHNational Cancer Institute2022 to 2025$2,399,999September 1, 2022August 31, 2027JANG, HAE LINreporter.nih.gov
Continuation of The Collaborative Islet Transplantation Registry (CITR)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,399,074September 15, 2022June 30, 2027PAYNE, ELIZABETH HOLLYreporter.nih.gov
Optimizing Surgical Transplant of CFTR Gene-Corrected Human Basal Stem Cells to the Upper AirwayNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,392,495March 1, 2021January 31, 2027NAYAK, JAYAKAR Vreporter.nih.gov
Promoting T cell reconstitution after hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,391,092January 1, 2024December 31, 2030DUDAKOV, JARRODreporter.nih.gov
Scalable and transplantable pancreatic islet organoids with engineered oxygenationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,390,830September 1, 2025August 31, 2029KOMATSU, HIROTAKEreporter.nih.gov
HIV Reservoir and Gene Modified Cell Dynamics Following Autologous Stem Cell TransplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,390,244January 13, 2023December 31, 2026HENRICH, TIMOTHY JENSENreporter.nih.gov
Epithelial stem/progenitor cells as repair agents in diffuse alveolar damageNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,388,592September 21, 2016May 31, 2025CHAPMAN, HAROLD Areporter.nih.gov
Development of a Microphysiological Organ-on-Chip System to Model AmyotrophicNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,385,538September 15, 2017February 28, 2024SVENDSEN, CLIVE NIELSreporter.nih.gov
Regulation of Ribosome Biogenesis in Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,385,337September 18, 2020August 31, 2025TONG, WEIreporter.nih.gov
Endothelial plasticity in cardiac repair after myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,384,851August 11, 2021July 31, 2025FAN, YIreporter.nih.gov
Mechanisms of Neural Stem Cell MechanoregulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,383,261May 1, 2012April 30, 2027SCHAFFER, DAVID Vreporter.nih.gov
CRISPR-induced cardiovascular progenitor cells to repair myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,382,655April 1, 2021March 31, 2026WANG, YIGANGreporter.nih.gov
From intra to intercellular regulatory networks that define cell type identityNIHNational Institute of General Medical Sciences2021 to 2025$2,381,600August 1, 2017July 31, 2027CAHAN, PATRICKreporter.nih.gov
Toxicology and Efficacy Studies of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2023$2,380,552September 18, 2023August 31, 2026SUN, MIAOreporter.nih.gov
The 4D nucleome of muscle regeneration in ischemia-induced tissue damage and repairNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,377,116September 20, 2020August 31, 2025DIAO, YARUIreporter.nih.gov
Cxcl12-Hedgehog signaling in cranial bone regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,375,113July 5, 2016June 30, 2027YANG, YINGZIreporter.nih.gov
Improve Lung Regeneration Through Targeting Tuft Cells Following Viral InfectionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,371,262August 20, 2021June 30, 2026QUE, JIANWENreporter.nih.gov
Developing Human Pluripotent Stem Cell Tools for Region-Specific Pain CircuitsNIHNational Institute of Neurological Disorders and Stroke2024$2,370,000September 6, 2024August 31, 2027IYER, NISHAreporter.nih.gov
Regulation and manipulation of the telomerase RNA component in hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,367,468December 1, 2015May 14, 2026AGARWAL, SUNEETreporter.nih.gov
Uncovering molecular effectors of mammalian agingNIHNational Institute on Aging2021 to 2022$2,366,000September 30, 2018May 19, 2025WAGERS, AMY JOreporter.nih.gov
Mechanotransduction and transcriptional regulation during artery developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,363,601September 1, 2015June 30, 2025RED-HORSE, MARYreporter.nih.gov
Trillion cell culture to fuel organ biofabricationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,361,000September 1, 2022August 31, 2027SKYLAR-SCOTT, MARK A.reporter.nih.gov
Therapeutic ECM Resorption in Cellular Systems and Precision Cut Lung Slices.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,360,154December 15, 2020November 30, 2025TSCHUMPERLIN, DANIEL J.reporter.nih.gov
CGT and ACD Inhibitors for SRT Treatment of Krabbe DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,357,715September 22, 2022August 31, 2027BONGARZONE, ERNESTO ROQUEreporter.nih.gov
Immunosuppression-free transplantation through placental mimicryNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,355,000September 14, 2021August 31, 2026WEAVER, JESSICA DIANEreporter.nih.gov
Lymphatic ERG signaling in scleroderma fibrosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,352,935July 7, 2022May 31, 2027TROJANOWSKA, MARIAreporter.nih.gov
Multipotent ABCB5-positive cell therapeutics for corneal diseaseNIHNational Eye Institute2021 to 2022$2,352,662April 1, 2018January 31, 2024FRANK, NATASHA Yreporter.nih.gov
3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,352,214September 2, 2021June 30, 2026PARR, ANN Mreporter.nih.gov
Intermittent fasting restores salivary gland function in Sjögren’s syndromeNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,348,947March 3, 2021February 28, 2027ZHOU, JINGreporter.nih.gov
Investigating the molecular mechanisms of HIV/AIDS associated neurological disorders using microglia and cerebral organoids derived from induced pluripotent stem cellsNIHNational Institute on Drug Abuse2021 to 2023$2,348,133September 1, 2019July 31, 2025RANA, TARIQ Mreporter.nih.gov
Replicative Potential of Muscle Stem CellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,347,486August 17, 2017July 31, 2027OLWIN, BRADLEY Breporter.nih.gov
Developing a platform for human somatic cell rejuvenation, expansion and genetic engineering using synthetic RNA moleculesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,346,523May 1, 2021April 30, 2027KOGUT, IGORreporter.nih.gov
Myeloid sphingolipid regulation of tissue resolution and regeneration responsesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,345,752September 21, 2022July 31, 2027HLA, TIMOTHY TUNreporter.nih.gov
Endothelial Cell Epigenetics and Blood-Brain Barrier.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,342,216April 15, 2021February 28, 2027THANKAMANI PANDIT, PEEYUSH KUMARreporter.nih.gov
Retinal sheet transplant impact on functional organization of visual cortex in retinal degenerate animal modelsNIHNational Eye Institute2022 to 2025$2,340,862May 1, 2022March 31, 2027LYON, DAVID Creporter.nih.gov
3D Encapsulation, Bioprinting and Controlled Delivery of Functionally Engineered EVs (FEEs)NIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,339,586June 18, 2021May 31, 2027RAVINDRAN, SRIRAMreporter.nih.gov
Molecular basis and protective efficacy of cross-neutralizing antibodies against four major respiratory virusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,338,206March 16, 2023February 29, 2028BOONYARATANAKORNKIT, JIMreporter.nih.gov
Multi-Tissue Craniofacial Engineering using 3D-BMP9-Notch-Synergized Graphene Citrate Composite ScaffoldsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,334,479April 1, 2021January 31, 2027REID, RUSSELL R.reporter.nih.gov
Chemotherapy-free cure of hemoglobin disorders through base editingNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,334,252September 1, 2023May 31, 2027BAUER, DANIEL EVANreporter.nih.gov
Regulators of epidermal growth and differentiationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,334,246February 17, 2015June 30, 2026SEN, GEORGE Lreporter.nih.gov
Efferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic HeartNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,334,070April 1, 2014January 31, 2025THORP, EDWARD BENJAMINreporter.nih.gov
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,333,316September 15, 2016May 31, 2025ZHANG, JIANYIreporter.nih.gov
Engineering the Vocal Fold MucosaNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,331,421February 1, 2000August 31, 2027THIBEAULT, SUSAN LYNNreporter.nih.gov
The Biology of Stem Cells in the Human Parasite Schistosoma MansoniNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,328,971February 1, 2016January 31, 2026COLLINS, JAMES Jreporter.nih.gov
Tissue biology studies of histone modification, nascent transcription, and post-transcription regulationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,328,764July 1, 2018June 30, 2028TUMBAR, TUDORITAreporter.nih.gov
Role of Brain Macrophages in the Pathogenesis and Treatment of Globoid Cell LeukodystrophyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,327,864May 3, 2021March 31, 2027BENNETT, FREDERICKreporter.nih.gov
ABCB5-positive stem cells for LSCD therapyNIHNational Eye Institute2023 to 2025$2,325,074June 1, 2016May 31, 2028FRANK, MARKUS H.reporter.nih.gov
Nutrient-dependent regulation of neural stem cell proliferation and neural circuit formationNIHNational Institute of General Medical Sciences2021 to 2025$2,324,951July 1, 2021June 30, 2027SIEGRIST, SARAH ELIZABETHreporter.nih.gov
Bottom-Up Assembly of Functional Salivary Gland TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,324,071May 1, 2021January 31, 2027JIA, XINQIAOreporter.nih.gov
Dynamic ECM-Mimicking Biomaterials for Ischemia TreatmentNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,323,983December 15, 2021November 30, 2026ZOLDAN, JANETAreporter.nih.gov
Novel roles for p27 as transcriptional co-regulator of cJun in stem cells and developmentNIHNational Cancer Institute2021 to 2024$2,319,039September 1, 2020August 31, 2025SLINGERLAND, JOYCE MARIEreporter.nih.gov
Chromatin-mediated mechanisms of transcription regulation in ES cellsNIHNational Institute of General Medical Sciences2021 to 2025$2,316,010September 17, 2019August 31, 2029HAINER, SARAH JANEreporter.nih.gov
The complex genetics of heart regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,315,896March 14, 2019August 31, 2027SUCOV, HENRY Mreporter.nih.gov
Pax2 Interacting Proteins in Development and DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,315,507January 15, 1999May 31, 2025DRESSLER, GREGORY Rreporter.nih.gov
Novel Intervention Approaches to Alleviate Allogeneic Transplant-Related Morbidity and MortalityNIHNational Cancer Institute2021 to 2024$2,315,110September 3, 2018January 31, 2026SORROR, MOHAMEDreporter.nih.gov
Extrinsic Mechanisms Governing Injury-Induced Axon DegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,312,486August 15, 2015March 31, 2026DEPPMANN, CHRISTOPHER Dreporter.nih.gov
Gut microbes modulate immune pathways in intestinal stem cells to influence their lineageNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,311,160June 12, 2020May 31, 2026BUCHON, NICOLASreporter.nih.gov
Role of Cholecystokinin in the Dentate GyrusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,307,005June 1, 2021March 31, 2027SONG, JUANreporter.nih.gov
Investigation of the role of VEGFA in harnessing cholangiocyte-driven liver regenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,306,170July 1, 2022April 30, 2027GOUON-EVANS, VALERIE Breporter.nih.gov
Neural Stem Cell-derived EVs for Improving Aged Brain FunctionNIHNational Institute on Aging2022 to 2025$2,306,114August 1, 2022April 30, 2027SHETTY, ASHOK Kreporter.nih.gov
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal CryptsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,304,272February 15, 2022January 31, 2026KLEIN, OPHIR Dreporter.nih.gov
IL-33 induced-lL-9 producing type 2 innate lymphoid cells in the regulation of acute lung injury after hematopoietic stem cell transplantation (HSCT) in pediatric patientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,303,969January 1, 2022June 30, 2026PACZESNY, SOPHIEreporter.nih.gov
Transplantation of MHC Homozygous Vascular Progenitors in PrimatesNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,302,970September 20, 2016May 31, 2025SLUKVIN, IGOR I.reporter.nih.gov
Training In Cell and Gene TherapyNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,300,213July 1, 2003July 31, 2028HESLOP, HELEN Ereporter.nih.gov
T cell invasion of the stem cell compartment during immune-mediated GI damageNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,299,846January 1, 2021December 31, 2025HANASH, ALAN Mreporter.nih.gov
Retinal Ganglion Cell Dendrite and Synapse Regeneration in Glaucoma: the Role of Insulin Signaling.NIHNational Eye Institute2021 to 2024$2,298,831June 1, 2020May 31, 2026DI POLO, ADRIANAreporter.nih.gov
The regulation of melanocyte stem cells by Wnt signalingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,297,460August 5, 2011July 31, 2026ITO, MAYUMIreporter.nih.gov
Cell Therapy for Neuroprotection in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,294,475December 15, 2017April 30, 2027ISHIBASHI, NOBUYUKIreporter.nih.gov
Targeted delivery of a proangiogenic and promyogenic protein for regeneration of diabetic ischemic limbsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,288,622May 2, 2022April 30, 2027GUAN, JIANJUNreporter.nih.gov
Endothelial tip cell-mediated angiogenesis and repair after neonatal strokeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,288,388September 22, 2022August 31, 2027GONZALEZ, FERNANDO FRANCISCOreporter.nih.gov
Amplification Mechanisms of Lung Endothelial Inflammation During Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,286,853January 15, 2021December 31, 2025REHMAN, JALEESreporter.nih.gov
Characterizing Human RPE Cell Proliferation to Advance Endogenous RegenerationNIHNational Eye Institute2021 to 2024$2,286,488February 1, 2021November 30, 2025TEMPLE, SALLYreporter.nih.gov
Biomechanical Determinants of Hematopoietic Stem Cell PotentialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,282,783January 15, 2018November 30, 2026WENZEL, PAMELA LYNNreporter.nih.gov
A Novel Semi-autonomous Surgeon-in-the-loop in situ Robotic Bioprinting System for Functional and Cosmetic Restoration of Volumetric Muscle Loss InjuriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,279,838September 1, 2022August 31, 2027ALAMBEIGI, FARSHIDreporter.nih.gov
Transcriptional Regulation of Lung Alveolar RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,270,370February 1, 2021December 31, 2024MORRISEY, EDWARD Ereporter.nih.gov
Tapeworm stem cells as drivers of regeneration and reproductionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,265,000March 5, 2021February 28, 2027ROZARIO, TANIAreporter.nih.gov
Biostimulatory nanofiber-hydrogel composite for soft tissue remodelingNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,263,220February 1, 2022January 31, 2027REDDY, SASHANK Kreporter.nih.gov
Understanding the role of stellate cells in the liver hematopoietic stem cell nicheNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,262,921August 1, 2020July 31, 2025DING, LEIreporter.nih.gov
Exploring networks underlying muscle stem cell identity - Resubmission - 1NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,259,735June 1, 2021May 31, 2027DYNLACHT, BRIAN Dreporter.nih.gov
High resolution lineage tracing of developmental hematopoiesisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,256,385May 5, 2023February 28, 2027CAMARGO, FERNANDOreporter.nih.gov
Harnessing Platelet-Endothelial Interactions for Exosome DeliveryNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,253,989April 1, 2019July 31, 2027CHENG, KEreporter.nih.gov
A stem cell activated cryogel bioscaffold that restores islet bioenergetics while providing oxygen and nutrients at extravascular sites of transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,251,861April 1, 2022March 31, 2027THAKOR, AVNESH SINHreporter.nih.gov
Elution of a Small Molecule from a Bio Ceramic Collagen Bone Graft Device Heals Bone while InhibitingBreast Cancer Bone MetastasesNIHNational Cancer Institute2021 to 2022$2,249,777November 30, 2021August 31, 2022MARGULIES, BRYAN SAMUELreporter.nih.gov
Diversity Supplement to R01 DC018042NIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,249,478April 1, 2021March 31, 2025WANG, HONGreporter.nih.gov
Transcriptional Control of Neonatal Heart RegenerationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,248,844December 6, 2021November 30, 2025OLSON, ERIC Nreporter.nih.gov
Gaze recovery during vestibular regenerationNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,240,600December 1, 2020November 30, 2026DICKMAN, J DAVIDreporter.nih.gov
Arthroscopic Raman Monitoring of Cartilage Content for PTOA Diagnosis and Chondroregenerative Treatment ResponseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,239,693August 2, 2022May 31, 2027ALBRO, MICHAEL Breporter.nih.gov
Targeting a ectonucleotidase in the heart with a monoclonal antibody to prevent post-infarct heart failureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,239,092August 14, 2023June 30, 2027DEB, ARJUNreporter.nih.gov
Molecular mechanisms mediating the soft tissue attachment to teethNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,238,127February 20, 2023January 31, 2028HELMS, JILL Areporter.nih.gov
Blockade of IL-23 for the Prevention of Graft Versus Host DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,237,924April 15, 2021March 31, 2026DROBYSKI, WILLIAM R.reporter.nih.gov
Contribution of macrophages in the HSC nicheNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,230,269April 1, 2021February 28, 2026STEIDL, ULRICHreporter.nih.gov
Intraoperative bioprinting of composite tissues with zonal stratification for craniomaxillofacial reconstructionNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,227,502January 1, 2020December 31, 2025OZBOLAT, IBRAHIMreporter.nih.gov
Novel nanoparticles to stimulate therapeutic angiogenesis in peripheral arterial diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,221,837May 2, 2022April 30, 2027NGUYEN, KYTAI TRUONGreporter.nih.gov
Multiplex base/prime editors for in vivo selection of modified HSPCs in hemoglobinopathyNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,218,334January 17, 2017December 31, 2025KIEM, HANS-PETERreporter.nih.gov
Molecular and Genetic Analysis of Fin Regeneration in ZebrafishNIHNational Institute of General Medical Sciences2021 to 2025$2,217,522July 1, 2020May 31, 2030KANG, JUNSUreporter.nih.gov
Intra-graft C1 esterase inhibitor therapy for deceased kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2024$2,216,525September 1, 2024August 31, 2031HEEGER, PETER SCOTTreporter.nih.gov
Intra-graft C1 esterase inhibitor therapy for deceased kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2025$2,216,525September 1, 2024August 31, 2031HEEGER, PETER SCOTTreporter.nih.gov
Microenvironmental Control of Capillary MorphogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,216,157July 20, 2007March 31, 2026PUTNAM, ANDREW Jreporter.nih.gov
Notch signaling and Bone Fracture HealingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,213,436February 1, 2011January 31, 2027KALAJZIC, IVOreporter.nih.gov
Inhibition of STAT3 and inflammatory cytokine productionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,211,650September 30, 1999January 31, 2027IVASHKIV, LIONEL Breporter.nih.gov
Strain-Programmed Bioadhesive Patch for Enhanced Diabetic Wound HealingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$2,210,864September 7, 2023August 31, 2025YUK, HYUNWOOreporter.nih.gov
Developmental Heterogeneity of Pulmonary Endothelial Phenotype at Single Cell ResolutionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,206,652September 15, 2021December 1, 2024ALVIRA, CRISTINA MARIAreporter.nih.gov
Progenitor cell states contributing to aging and lung cancerNIHNational Cancer Institute2021 to 2025$2,206,534September 24, 2021August 31, 2026HAIGIS, MARCIAreporter.nih.gov
Enhancing endothelial cell engraftment via transplantation of exogenous mitochondriaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,206,197December 20, 2020November 30, 2024MELERO-MARTIN, JUAN Mreporter.nih.gov
Engineering the Stem Cell Microenvironment for Lymphatic RegenerationNIHNational Institute of General Medical Sciences2021 to 2025$2,205,356July 1, 2021May 31, 2027HANJAYA-PUTRA, DONNYreporter.nih.gov
Variant Determinants of African American Limb Pathology in Peripheral Arterial DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,205,005April 1, 2021August 1, 2024MCCLUNG, JOSEPH MATTHEWreporter.nih.gov
Comparison of normal aging with Alzheimer's Disease: cellular, synaptic, and vascular indices affecting brain plasticity and neurogenesisNIHNational Institute on Aging2023 to 2025$2,205,002September 21, 2023May 31, 2028DUPONT, MAURA BOLDRINIreporter.nih.gov
Mineralized collagen composite to accelerate craniofacial bone regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,203,403May 3, 2021April 30, 2027HARLEY, BRENDAN A.reporter.nih.gov
Coordinated regeneration of lung epithelial and endothelial compartmentsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,201,693August 20, 2022July 31, 2026VAUGHAN, ANDREWreporter.nih.gov
Ex-vivo bioengineered technology to unravel dysfunction due to non-alcoholic steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,201,102July 1, 2023April 30, 2027WERTHEIM, JASON Areporter.nih.gov
Mechanism of action of PTH: New signaling components that regulate bone formation and bone marrow fatNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,199,383May 5, 2020March 31, 2026BARON, ROLAND Ereporter.nih.gov
Biology of Submucosal Gland Stem Cells in the AirwayNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,198,254June 20, 2022May 31, 2025ENGELHARDT, JOHN Freporter.nih.gov
Strategies to Enhance Engineered Heart Tissue Based Myocardial RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,196,794January 1, 2023November 30, 2026ZHU, WUQIANGreporter.nih.gov
Role of Stress Granule Protein Aggregation in Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,196,651July 1, 2020June 30, 2026TWISS, JEFFERY Lreporter.nih.gov
Pathways underlying recovery of injured urethral sphincter and a novel regenerative biomaterial interventionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,191,647July 15, 2021April 30, 2026ALPERIN, MARIANNAreporter.nih.gov
Functional and histological changes to peripheral innervation following spinal cord stimulation in patients with painful diabetic neuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,189,785September 12, 2023July 31, 2028TOWNSEND, KRISTY Lreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Stanford UniversityStanford, CA146$136.1 million0$0
University of Michigan at Ann ArborAnn Arbor, MI107$118.4 million0$0
University of PennsylvaniaPhiladelphia, PA117$113.7 million0$0
University of California, San FranciscoSan Francisco, CA99$108.7 million0$0
Medical College of WisconsinMilwaukee, WI34$103.8 million0$0
Columbia University Health SciencesNew York, NY77$94.4 million0$0
Duke UniversityDurham, NC89$94.1 million0$0
University of Southern CaliforniaLos Angeles, CA54$90.6 million0$0
Boston Children's HospitalBoston, MA64$90.4 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA90$86.6 million0$0
University of California, San DiegoLa Jolla, CA72$83.3 million0$0
Johns Hopkins UniversityBaltimore, MD90$79.9 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH44$68.7 million0$0
University of California Los AngelesLos Angeles, CA71$65.3 million0$0
University of WashingtonSeattle, WA70$63.9 million0$0
Baylor College of MedicineHouston, TX57$63.7 million0$0
Fred Hutchinson Cancer CenterSeattle, WA35$60.7 million0$0
Washington UniversitySaint Louis, MO66$60 million0$0
Yale UniversityNew Haven, CT50$54 million0$0
Emory UniversityAtlanta, GA55$53.8 million0$0
University of Illinois at ChicagoChicago, IL52$53.6 million0$0
Ut Southwestern Medical CenterDallas, TX39$52.7 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY40$50.7 million0$0
Massachusetts General HospitalBoston, MA53$48.5 million0$0
Ohio State UniversityColumbus, OH48$47.5 million0$0
University of MinnesotaMinneapolis, MN47$46.7 million0$0
Brigham and Women's HospitalBoston, MA33$46.4 million0$0
University of VirginiaCharlottesville, VA36$46.2 million0$0
University of California-IrvineIrvine, CA42$45.5 million0$0
Northwestern University at ChicagoChicago, IL37$44 million0$0
Indiana University IndianapolisIndianapolis, IN47$41.9 million0$0
University of ArizonaTucson, AZ13$41.5 million0$0
Mayo Clinic RochesterRochester, MN34$40.9 million0$0
University of Wisconsin-MadisonMadison, WI51$36.7 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA28$36 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA27$34.3 million0$0
Beckman Research Institute/city of HopeDuarte, CA18$33.4 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY25$32.7 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA28$32.2 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC26$31.6 million0$0
University of Colorado DenverAurora, CO33$28.9 million0$0
New York University School of MedicineNew York, NY29$28.9 million0$0
Case Western Reserve UniversityCleveland, OH20$28.7 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX22$27.7 million0$0
University of KentuckyLexington, KY25$27.7 million0$0
Weill Medical Coll of Cornell UnivNew York, NY24$27.7 million0$0
Albert Einstein College of MedicineBronx, NY32$27.4 million0$0
University of California at DavisDavis, CA36$27.2 million0$0
Harvard UniversityCambridge, MA32$26.1 million0$0
Oregon Health & Science UniversityPortland, OR27$26.1 million0$0
University of Miami School of MedicineCoral Gables, FL30$25.1 million0$0
University of RochesterRochester, NY25$24.7 million0$0
University of FloridaGainesville, FL30$24.5 million0$0
Cornell UniversityIthaca, NY20$24.5 million0$0
Regents of the University of IdahoMoscow, ID2$23.4 million0$0
Georgia Tech Research CorporationAtlanta, GA28$23.1 million0$0
Boston University Medical CampusBoston, MA30$21.4 million0$0
Vanderbilt University Medical CenterNashville, TN18$20.6 million0$0
Research Inst Nationwide Children's HospColumbus, OH18$20.6 million0$0
University of Alabama at BirminghamBirmingham, AL24$20.5 million0$0
University of Maryland BaltimoreBaltimore, MD23$19.1 million0$0
University of Connecticut SCH of Med/dntFarmington, CT24$18.8 million0$0
University of Colorado at BoulderBoulder, CO14$18.8 million0$0
University of UtahSalt Lake City, UT19$18.7 million0$0
Medical University of South CarolinaCharleston, SC14$18.6 million0$0
Massachusetts Institute of TechnologyCambridge, MA17$18.4 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL14$18.3 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA17$17.9 million0$0
University of CincinnatiCincinnati, OH18$17.6 million0$0
University of Oregon EugeneEugene, OR23$17.5 million0$0
Columbia UniversityNew York, NY15$17.2 million0$0
Lurie Children's Hospital of ChicagoChicago, IL11$16.6 million0$0
Harvard Medical SchoolBoston, MA22$16.6 million0$0
University of Missouri-ColumbiaColumbia, MO22$16.5 million0$0
Methodist Hospital Research InstituteHouston, TX10$16.2 million0$0
University of IowaIowa City, IA21$16.2 million0$0
SUNY at BuffaloAmherst, NY14$15.8 million0$0
Wake Forest University Health SciencesWinston-Salem, NC14$15.6 million0$0
University of California-BerkeleyBerkeley, CA15$15.5 million0$0
National Jewish HealthDenver, CO10$15.3 million0$0
Texas A&m University Health Science CTRCollege Station, TX19$15.2 million0$0
North Carolina State UniversityRaleigh, NC15$15.1 million0$0
Tufts University BostonBoston, MA14$15 million0$0
ST. Jude Children's Research HospitalMemphis, TN15$14.8 million0$0
Northwestern UniversityChicago, IL15$14.7 million0$0
Tulane University of LouisianaNew Orleans, LA12$14.7 million0$0
University of Texas at AustinAustin, TX18$14.5 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA13$14.3 million0$0
University of LouisvilleLouisville, KY17$14.3 million0$0
Trustees of Boston UniversityBoston, MA17$13.5 million0$0
Michigan State UniversityEast Lansing, MI14$13.3 million0$0
Scripps Research Institute, theLa Jolla, CA7$13.2 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA10$12.9 million0$0
Purdue UniversityWest Lafayette, IN13$12.3 million0$0
University of TX MD Anderson Can CTRHouston, TX11$12.2 million0$0
University of Georgia Research Foundation IncAthens, GA11$12 million0$0
University of South FloridaTampa, FL10$11.8 million0$0
Regenerative Research FoundationAlbany, NY7$11.7 million0$0
Rutgers University New BrunswickNew Brunswick, NJ12$11.6 million0$0
Mayo Clinic ArizonaScottsdale, AZ6$11 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,894$919,615,8110$0
20241,996$904,939,1520$0
20232,087$922,399,7750$0
20222,092$890,511,0650$0
20212,132$897,338,5340$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 30 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 8 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 7 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 4 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIHJuly 17, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)PAR-24-279NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 493 awards here
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)PAR-24-280NIH93.846November 2, 2026Not listedSame assistance listing 93.846 as 493 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.846November 23, 2026$375,000Same assistance listing 93.846 as 493 awards here
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0RFA-AR-26-006NIH93.846December 1, 2026Not listedSame assistance listing 93.846 as 493 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.846December 4, 2026Not listedSame assistance listing 93.846 as 493 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 493 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 493 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.846January 7, 2027Not listedSame assistance listing 93.846 as 493 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.846January 15, 2027$350,000Same assistance listing 93.846 as 493 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.846January 27, 2027$500,000Same assistance listing 93.846 as 493 awards here
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)PAR-25-141NIH93.846March 4, 2027Not listedSame assistance listing 93.846 as 493 awards here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin DiseasesPAR-27-109NIH93.846March 4, 2027$600,000Same assistance listing 93.846 as 493 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 493 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.