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Data / Research funding / Pneumonia

Pneumonia: 599 NIH awards ($644.9M) to 179 organizations

599 NIH awards ($644.9M) in the NIH spending category Pneumonia, to 179 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 599 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE)NIHNational Heart, Lung, and Blood Institute2023 to 2025$16,153,090May 1, 2023April 30, 2029SELF, WESLEY Hreporter.nih.gov
Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,773,513January 17, 2018December 31, 2027WUNDERINK, RICHARD Greporter.nih.gov
Disordered Proteostasis as a Driver of Disease in the Aging LungNIHNational Institute on Aging2021 to 2024$8,161,610July 1, 2015March 31, 2025BUDINGER, GR SCOTTreporter.nih.gov
Adjuvant Development of the TLR4 Ligand BECC470s For Use in Influenza, S. aureus, and P. aeruginosa VaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$7,143,498September 30, 2023September 29, 2028SORENSON, GREGORYreporter.nih.gov
Developing Teixobactin for Respiratory InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,154,703March 22, 2021February 28, 2027HUGHES, DALLASreporter.nih.gov
1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)NIHNational Heart, Lung, and Blood Institute2021 to 2023$5,715,477September 23, 2019August 31, 2025LEVITT, JOSEPH ERICreporter.nih.gov
Inducible epithelial resistance: a program investigating mechanisms to protect against acute and chronic complications of pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,382,400March 5, 2019February 28, 2026EVANS, SCOTT E.reporter.nih.gov
Preclinical Pulmonary Fibrosis, an opportune rare disease cohortNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,290,758August 20, 2020July 31, 2026SCHWARTZ, DAVID ALBERTreporter.nih.gov
Derivation and Validation of the Pediatric Community-Acquired Pneumonia Severity (PedCAPS) ScoreNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,862,565February 1, 2023January 31, 2028FLORIN, TODD ADAMreporter.nih.gov
Inborn errors of immunity in patients with life-threatening COVID-19NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,707,765July 12, 2021June 30, 2026CASANOVA, JEAN-LAURENTreporter.nih.gov
THE ROLE OF THE NON-CANONICAL INFLAMMASOME IN INNATE IMMUNITYNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,707,189June 11, 2021May 31, 2027AMER, AMAL Oreporter.nih.gov
Programming of PMN host-defense function during transendothelial migrationNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,648,697June 11, 1993June 30, 2027KOMAROVA, YULIA Areporter.nih.gov
Development of ureadepsipetides for drug-resistant infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,597,406December 17, 2018November 30, 2024LAFLEUR, MICHAELreporter.nih.gov
CD4_T-cell_Immunity_in_the_LungNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,557,478February 1, 2018January 31, 2025KOLLS, JAY Kreporter.nih.gov
Novel mechanisms regulating immunity to respiratory virus infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,546,288August 2, 2023July 31, 2027PAUST, SILKEreporter.nih.gov
Protective immunity elicited by distinct polysaccharide antigens of classical and hypervirulent KlebsiellaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,483,730September 1, 2023August 31, 2028ROSEN, DAVID A.reporter.nih.gov
Novel bi-specific immunotherapeutic against high-threat Gram-negative pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,410,042February 21, 2019January 31, 2025PERLIN, DAVID Sreporter.nih.gov
Development of Gene-Silencing Therapeutics for Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,379,247August 1, 2019July 31, 2025GREENBERG, DAVID ELIHUreporter.nih.gov
Cross-Kingdom Vaccine Targeting Healthcare-Associated Priority PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,343,171January 9, 2019December 31, 2024IBRAHIM, ASHRAF S.reporter.nih.gov
A Phase III Randomized Controlled Trial of Azithromycin for RSV-induced Respiratory Failure in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,324,945August 1, 2021July 31, 2027KONG, MICHELEreporter.nih.gov
The role of Chlamydia pneumoniae infection in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$3,300,943September 30, 2021June 30, 2027CROTHER, TIMOTHY ROBERTreporter.nih.gov
Pulmonary pathophysiology sub-phenotypes of pneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,223,607February 1, 2022January 31, 2027MIZGERD, JOSEPH Preporter.nih.gov
Uncovering associations of variant infection with COVID-19 disease severity in childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$3,214,599January 1, 2021June 30, 2023CHIU, CHARLES YENreporter.nih.gov
Development of peptide nucleic acid antibioticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,164,488February 10, 2021January 31, 2025ARYA, DEV PRIYAreporter.nih.gov
Cardiovascular Risk, Vascular and Kidney Damage in COVID-19 SurvivorsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,114,564January 20, 2022December 31, 2026CHIRINOS MEDINA, JULIO ALONSOreporter.nih.gov
Immunological characterization of rationally-designed vaccines against plague in mice and non-human primate modelsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,082,735February 1, 2021July 31, 2026CHOPRA, ASHOK Kreporter.nih.gov
Novel Strategies for Antibiotic Combinations to Combat Gram-negative SuperbugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,081,358December 20, 2019November 30, 2025TSUJI, BRIANreporter.nih.gov
Novel delivery platform and antigen design for an effective COVID-19 vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,066,236August 11, 2020July 31, 2027MITTAL, SURESH Kreporter.nih.gov
Genetic Analysis of COVID-19 Susceptibility and Resistance Determinants in the Collaborative CrossNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,064,576September 25, 2020August 31, 2025HEISE, MARK Treporter.nih.gov
Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD preventionNIHNational Institute on Aging2021 to 2025$3,052,023September 30, 2021June 30, 2027OUKRAINTSEVA, SVETLANA V.reporter.nih.gov
CoPARC: Colorado Pulmonary-Alcohol Research CollaborativeNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,045,581August 1, 2011April 30, 2029BURNHAM, ELLEN Lreporter.nih.gov
Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated PneumoniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,027,494July 1, 2023June 30, 2028NIZET, VICTORreporter.nih.gov
Evaluating darobactins as antimicrobial agentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,000,880April 1, 2021March 31, 2026LEWIS, KIMreporter.nih.gov
Optimization of orally bioavailable inhibitors for the treatment of COVID-19 and other human coronavirus infectionsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,999,998June 7, 2023May 31, 2027COBURN, GLENreporter.nih.gov
Development of a Dual-Targeting ClpP Activating AntibioticNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,999,619September 1, 2023August 31, 2026LAFLEUR, MICHAELreporter.nih.gov
Aminoglycosides with reduced ototoxicityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,999,400August 1, 2020February 28, 2026ARYA, DEV PRIYAreporter.nih.gov
Prevention and Treatment of Pneumocystis PneumoniaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,969,486May 21, 2020April 30, 2026NORRIS, KAREN Areporter.nih.gov
Novel G protein-based RSV vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,967,937August 1, 2020March 31, 2027LI, SHENGQIANGreporter.nih.gov
Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs’NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,944,400June 21, 2022May 31, 2027RAO, GAURI Greporter.nih.gov
Targeting abnormal alveolar immune activation and failed epithelial repair in COVID-19NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,933,325April 1, 2022March 31, 2026MISHARIN, ALEXANDERreporter.nih.gov
Dual drug delivery to lung/blood interface in respiratory infections.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,888,500April 20, 2021March 31, 2025MUZYKANTOV, VLADIMIR Rreporter.nih.gov
Development of an RSV vaccine for the elderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,887,888March 2, 2020February 28, 2026MORRISON, TRUDY G.reporter.nih.gov
Dissecting Yersinia Yop Targets in NeutrophilsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,883,504February 11, 2022January 31, 2027MECSAS, JOAN Creporter.nih.gov
A New Class of Broad-Spectrum Antibacterial Agents to Treat Multi-Drug Resistant PathogensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,858,436July 21, 2023June 30, 2027SEBAHAR, PAULreporter.nih.gov
Betacoronaviruses: activation and antagonism of host innate immune responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,828,524May 24, 2018April 30, 2028WEISS, SUSAN Rreporter.nih.gov
Molecular Determinants of Usual Interstitial Pneumonia (UIP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,826,957April 1, 2022March 31, 2027SCHWARTZ, DAVID ALBERTreporter.nih.gov
Central role of Caspase-8 in control of host tolerance and resistance mechanisms in pulmonary macrophage populations during severe respiratory infectionsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,808,365August 15, 2023May 31, 2027JAMIESON, AMANDA Mreporter.nih.gov
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,783,450March 1, 2020June 30, 2029SINGER, BENJAMIN DAVIDreporter.nih.gov
Yersinia Outer-Membrane-Vesicle Vaccines Against Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,776,243January 25, 2022December 31, 2026SUN, WEIreporter.nih.gov
Child Lung Development Following a Cookstove Intervention: Evidence from GRAPHSNIHNational Institute of Environmental Health Sciences2021 to 2025$2,763,681July 1, 2017February 29, 2028JACK, DARBYreporter.nih.gov
Systems-based pharmacologic modelling to elucidate beta-lactam clinical pharmacodynamics and define optimal dosing regimens in severe pneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,734,140July 11, 2022June 30, 2027RHODES, NATHANIEL JAMESreporter.nih.gov
Sensing living P. aeruginosa using D-alanine derived radiotracersNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,693,051May 1, 2021January 31, 2026WILSON, DAVID Mreporter.nih.gov
Nosocomial pneumonias impair cognitive functionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,684,149April 1, 2018August 31, 2027LIN, MIKEreporter.nih.gov
Amyloid-mediated cognitive dysfunction in bacterial pneumonia after TBINIHNational Institute on Aging2025$2,663,195September 15, 2025August 31, 2029WAGENER, BRANT Mreporter.nih.gov
Targeting Pneumococcal TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,658,920February 1, 2020January 31, 2026WEISER, JEFFREY NEALreporter.nih.gov
Macrorecombination in isolated cell pairs via natural genetic transformationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,657,698May 21, 2021April 30, 2027EDDINGTON, DAVIDreporter.nih.gov
Monoclonal Antibody to Combat Pseudomonas AeruginosaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,646,807August 15, 2023July 31, 2028GOLDBERG, JOANNA Breporter.nih.gov
The interface between L. pneumophila manipulation of host endoplasmic reticulum and innate immune subterfugeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,645,600February 20, 2020January 31, 2026ISBERG, RALPH R.reporter.nih.gov
Mechanisms of Pneumococcal Persistence During CarriageNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,644,208April 1, 1996June 30, 2029WEISER, JEFFREY NEALreporter.nih.gov
Development of a Mucosal Nanoemulsion-Adjuvanted RSV Vaccine using Recombinant Pre-Fusion F ProteinNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,617,783September 1, 2020December 31, 2025TRABBIC, KEVINreporter.nih.gov
GMP manufacturing and IND Filing of IN-002, a potent inhaled muco-trapping antibody therapy for Respiratory Syncytial VirusNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,605,456June 1, 2023May 31, 2027HUTCHINS, JEFF Treporter.nih.gov
A multivalent O-antigen bioconjugate vaccine for the prevention of Klebsiella pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,591,387July 15, 2022July 31, 2027HARDING, CHRISTIANreporter.nih.gov
Innate Immune Clearance of Host-Adapted Pulmonary PathogensNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,586,182January 11, 2017November 30, 2024PRINCE, ALICE Sreporter.nih.gov
Innate immune-mediated control of pulmonary Legionella pneumophila infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,572,725November 16, 2015June 30, 2027SHIN, SUNNYreporter.nih.gov
Rapid, Breath Volatile Metabolite-Based Diagnosis, Species Identification, and Antibiotic Resistance Profiling in Bacterial PneumoniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,571,160February 15, 2023January 31, 2028KOO, SOPHIAreporter.nih.gov
Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,541,116September 19, 2022July 31, 2027LAI, SAMUELreporter.nih.gov
Pneumonia BiologyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,516,358January 11, 2017December 31, 2024MIZGERD, JOSEPH Preporter.nih.gov
hHv1 channels in neutrophils and the innate immune inflammatory responseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,426,520August 5, 2022June 30, 2027GOLDSTEIN, STEVE A Nreporter.nih.gov
Targeting Estrogenic pathways in Tregs to promote ARDS resolutionNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,413,250June 1, 2022May 31, 2026D'ALESSIO, FRANCO RAFAELreporter.nih.gov
Let-7b in Extracellular Vesicles Secreted by Bronchial Epithelial Cells Increases the Antibiotic Sensitivity of PseudomonasNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,409,204December 15, 2020November 30, 2025STANTON, BRUCE A.reporter.nih.gov
SBIR: In vivo validation and IND-enabling development of MM004, a bispecific inhaled immunotherapy for RSV and MPVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,380,033March 4, 2021February 28, 2026CONE, RICHARDreporter.nih.gov
Fungal dysbiosis regulation of post-influenza bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,376,545July 16, 2021June 30, 2025CHEN, PETERreporter.nih.gov
A prophylactic vaccine to prevent colonization by Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,345,744December 27, 2022November 30, 2027PICKING, WENDY L.reporter.nih.gov
Cardiac microlesion formation during invasive pneumococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,308,740November 1, 2014May 31, 2030ORIHUELA, CARLOS Jreporter.nih.gov
Evaluation of pregnancy on vaccine-induced immunity and protection in a pre-clinical model of RSV infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,306,179September 24, 2020August 31, 2025NORRIS, KAREN Areporter.nih.gov
Follistatin-like 1 Mediated Host Defense in Bacterial PneumoniaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,305,697July 1, 2022June 30, 2027CAMPFIELD, BRIAN Treporter.nih.gov
IL-33 induced-lL-9 producing type 2 innate lymphoid cells in the regulation of acute lung injury after hematopoietic stem cell transplantation (HSCT) in pediatric patientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,303,969January 1, 2022June 30, 2026PACZESNY, SOPHIEreporter.nih.gov
Preclinical development of a synthetic lung surfactant dry powder aerosol for hypoxemia or acute respiratory distress syndrome patients receiving different modes of ventilation supportNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,301,184July 1, 2023June 30, 2027LONGEST, P. WORTHreporter.nih.gov
Deciphering the role of peroxisomes in bacterial pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,298,625September 19, 2022July 31, 2027O'CONNOR, TAMARAreporter.nih.gov
Prevalence effects in visual search: Theoretical and practical implicationsNIHNational Eye Institute2021 to 2025$2,283,459April 1, 2007June 30, 2029WOLFE, JEREMY Mreporter.nih.gov
LOX-1 as a protective countermeasure in response to lung infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,274,599June 15, 2023May 31, 2027QUINTON, LEEreporter.nih.gov
Bioactivities of pneumococcal cell wall in neuropathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,255,100November 4, 2016January 31, 2027TUOMANEN, ELAINE Ireporter.nih.gov
Rapid, Breath Volatile Metabolite-Based Diagnostic for In Vivo Identification and Antibiotic Resistance Profiling of Bacterial Pathogens in Ventilator-Associated PneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,232,574June 20, 2018May 31, 2025KOO, SOPHIAreporter.nih.gov
Mechanistic modeling of the innate immune responses of the human lung to understand the inter-individual heterogeneity of COVID-19 pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,227,734July 1, 2023June 30, 2027MEHRAD, BORNAreporter.nih.gov
Targeting RIPK3 in Flu-Associated Lung InjuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,222,961September 18, 2019August 31, 2025BALACHANDRAN, SIDDHARTHreporter.nih.gov
Coordinated regeneration of lung epithelial and endothelial compartmentsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,201,693August 20, 2022July 31, 2026VAUGHAN, ANDREWreporter.nih.gov
Novel mechanisms of Alveolar Macrophage-Dependent Antifungal Innate ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,192,702January 8, 2020December 31, 2025WRIGHT, TERRY Wreporter.nih.gov
Impact of inflammatory lipids on Yersinia pestis infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,171,406July 14, 2023June 30, 2027LAWRENZ, MATTHEW Breporter.nih.gov
Developmental Exposures to Arsenic: Pneumonia, Immunity, and Microbiomes (DEAPIM)NIHNational Institute of Environmental Health Sciences2023 to 2025$2,157,462February 5, 2022December 31, 2026PARVEZ, MUHAMMAD Freporter.nih.gov
Novel bi-specific immunoprophylactics against multi-drug resistant Gram-negativebacterial infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,153,664March 22, 2019April 30, 2024PERLIN, DAVID Sreporter.nih.gov
Effective Primary care practices that Enhance Recovery Trajectories after pneumonia (EXPERT)NIHNational Heart, Lung, and Blood Institute2023 to 2025$2,148,392September 15, 2023June 30, 2028IWASHYNA, THEODORE Jreporter.nih.gov
THE IMPACT OF ADVANCED AGE AND SEX ON HUMORAL IMMUNITY TO STREPTOCOCCUS PNEUMONIAENIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,121,108September 1, 2022August 31, 2027HAAS, KAREN Mreporter.nih.gov
Structure and Function of Legionella pneumophila Lysine MethyltransferasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,118,862March 21, 2022February 28, 2027TRIEVEL, RAYMOND Creporter.nih.gov
Macrophage-targeting Nanoplatforms as Immunotherapy against Pulmonary InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,117,352July 1, 2017November 30, 2028SAILOR, MICHAEL Jreporter.nih.gov
TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,097,481February 1, 2021January 31, 2027SCHERAGA, RACHEL GREENBERGreporter.nih.gov
Interleukin-27 in host response to Legionella infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,096,982July 1, 2023June 30, 2027BOSMANN, MARKUSreporter.nih.gov
IDENTIFICATION AND CHARACTERIZATION OF T CELL EPITOPES FROM BACTERIAL PATHOGENS CAUSING PNEUMONIANIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,079,792September 30, 2025September 29, 2026PETERS, BJOERNreporter.nih.gov
Transcriptional Regulation of Migrating Neutrophils during PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,062,500July 1, 2021June 30, 2027TRABER, KATRINAreporter.nih.gov
Pharmacokinetics analysis from first-in-human study of IN-002, a potent inhaled muco-trapping antibody therapy for RSVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,049,871June 21, 2024May 31, 2027SCOTT, DAVID Wreporter.nih.gov
IND-enabling development for IN-003, an inhaled mAb therapy against human metapneumovirus infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,049,821May 15, 2024April 30, 2027HUTCHINS, JEFF Treporter.nih.gov
Influenza A Inhibits TH17 Host Defense Against Bacterial PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,049,603January 1, 2012March 31, 2026ALCORN, JOHN Freporter.nih.gov
IND-enabling development for IN-002, an inhaled muco-trapping mAb against respiratory syncytial virusNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,042,193July 12, 2022June 30, 2024HUTCHINS, JEFF Treporter.nih.gov
Molecular Insights into the Uropathogenesis of MDR Acinetobacter baumanniiNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,021,352February 6, 2019January 31, 2025FELDMAN, MARIOreporter.nih.gov
Cellular and molecular mechanisms of alveolar repairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,019,414August 1, 2023May 31, 2027DESAI, TUSHAR JASUBHAIreporter.nih.gov
Adjuvant Development of the TLR4 Ligand BECC470s For Use in Influenza, S. aureus, and P. aeruginosa VaccinesNIHNational Institute of Allergy and Infectious Diseases2025$2,018,199September 30, 2023September 29, 2026SORENSON, GREGORYreporter.nih.gov
Consequences of Direct Viral-Bacterial InteractionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,014,549January 5, 2022December 31, 2026ROSCH, JASON W.reporter.nih.gov
An immunodominance-based Pan-Pneumovirus vaccine for protection against RSV and hMPVNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,007,500June 6, 2023May 31, 2028MOUSA, JARRODreporter.nih.gov
Pneumocystis: Macrophage & Epithelial ActivationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,005,500July 10, 1993January 31, 2027LIMPER, ANDREW Hreporter.nih.gov
Preclinical development of an immunomodulatory agent capable of mitigating SARS-CoV-2 virus related hypercytokinemiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,000,000March 6, 2021February 29, 2024CRAIGO, JODI Kreporter.nih.gov
Development of WecA-targeting immune potentiators to treat carbapenem-resistant Enterobacteriaceae (CRE) infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,000,000August 1, 2019July 31, 2024ROEMER, TERRYreporter.nih.gov
A new class of antibiotic to address Antimicrobial ResistanceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,995May 1, 2024April 30, 2027TESTA, CHARLESreporter.nih.gov
ELD607 Orai1 Antagonist Increases Bacterial Clearance from the LungNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,988,078June 22, 2020June 30, 2025TARRAN, ROBERTreporter.nih.gov
Towards a New Generation of Glycoengineered Pneumococcal Bioconjugate VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,977,893February 22, 2017January 31, 2024HARDING, CHRISTIANreporter.nih.gov
Lung Macrophage Memory Development and Responses in Secondary Pneumonia and SepsisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,972,366August 27, 2021July 31, 2026MISHRA, BIBHUTI BHUSANreporter.nih.gov
CMC of Peptide Formulation for the Treatment of ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,967,733June 1, 2022May 31, 2025CASTILLO, GERARDO M.reporter.nih.gov
The role of neutrophils in the age-driven decline in anti-pneumococcal vaccine responsesNIHNational Institute on Aging2021 to 2025$1,966,375September 30, 2021May 31, 2027BOU GHANEM, ELSAreporter.nih.gov
Tissue niches for ILC3 development in newborn's lungNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,949,066January 1, 2021March 14, 2025DESHMUKH, HITESHreporter.nih.gov
Microbiota Regulation of Pulmonary Complications Post-HCTNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,941,600September 20, 2021August 31, 2026ZHOU, XIAOFENGreporter.nih.gov
Improved Therapeutics and Diagnostics for Pneumocystis PneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,932,841February 1, 2016October 31, 2026KOLLS, JAY Kreporter.nih.gov
Impact of Aging on Oxysterol Regulation of Alveolar Macrophage Function during S. pneumoniaeNIHNational Institute on Aging2023 to 2025$1,932,027September 1, 2023May 31, 2028STOUT DELGADO, HEATHER WINONAreporter.nih.gov
Molecular mechanisms underlying organ penetration in disseminated pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,924,214November 1, 2022October 31, 2027ORIHUELA, CARLOS Jreporter.nih.gov
Elucidating the role of type I interferon signaling and macrophage-derived inflammation in the juvenile host with viral pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,898,753May 8, 2023February 28, 2027COATES, BRIA Mreporter.nih.gov
Colistin resistance in extensively drug-resistant Gram-negative pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,869,812March 15, 2014March 31, 2025DOI, YOHEIreporter.nih.gov
Common Post-Infectious Premature Epigenetic AgingNIHNational Institute on Aging2023 to 2025$1,844,091August 15, 2023April 30, 2028DINARDO, ANDREW Rreporter.nih.gov
Siderophore based molecular imaging of pulmonary infectionsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,833,928July 1, 2023June 30, 2028KOTAGIRI, NALINIKANTHreporter.nih.gov
Antibiotic tolerance: membraneless organelles and autolysin regulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,820,000May 5, 2022April 30, 2027TUOMANEN, ELAINE Ireporter.nih.gov
Lead optimization of a novel cyclic aryl-indole efflux pump inhibitor (EPI) series in combination with levofloxacin against Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,799,789May 1, 2024April 30, 2027PARHI, AJIT Kreporter.nih.gov
DEVELOPMENT OF A LIPOSOMAL PNEUMOCOCCAL VACCINE FOR CLINICAL READINESSNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,796,584April 24, 2020March 31, 2023JONES, CHARLES HOUSTONreporter.nih.gov
Endolysins as tools to eradicate pneumococcal biofilms and development ofprotective immunityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,770,586December 9, 2022November 30, 2027GONZALEZ-JUARBE, NORBERTOreporter.nih.gov
Molecular Mechanisms Regulating Bacterial Two-component Signaling SystemsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,766,612February 8, 2023January 31, 2028FUENTES, ERNESTO JORGEreporter.nih.gov
Therapeutic Use of High Molecular Weight Hyaluronic Acid in Acute Lung Injury Following Severe Bacterial Pneumonia or SepsisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,737,261May 1, 2020August 31, 2023LEE, JAE WOOreporter.nih.gov
Mechanism and targeting of inflammasome activation in lung inflammation and injuryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,696,153February 16, 2023January 31, 2028LIU, GANGreporter.nih.gov
Legionella effectors reveal novel signaling function for the ribosome quality control (RQC) pathwayNIHNational Institute of General Medical Sciences2021 to 2024$1,677,236June 15, 2016May 31, 2025MUKHERJEE, SHAERIreporter.nih.gov
A redox-sensitive switch in the macrophage nucleus regulates acute phase inflammatory injuryNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,671,361June 1, 2022May 31, 2026BONINI, MARCELO G.reporter.nih.gov
PspA binds necroptotic cells to cause disease and transmitNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,641,325September 24, 2020August 31, 2025ORIHUELA, CARLOS Jreporter.nih.gov
Impact of nucleotide metabolism on bacterial clearanceNIHNational Institute of General Medical Sciences2022 to 2025$1,637,144August 15, 2022July 31, 2027RIQUELME COLET, SEBASTIAN ALEJANDROreporter.nih.gov
A Phase II Study Evaluating the Safety and Efficacy of Whole-Cell Pneumococcal Vaccine (wSp) in Reducing Nasopharyngeal Colonization by Streptococcus pneumoniae in Young ChildrenNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,616,462March 15, 2024February 29, 2028PICHICHERO, MICHAEL Ereporter.nih.gov
Liposomal Encapsulation Vaccine Design for Pneumococcal Disease in Aged SubjectsNIHNational Institute on Aging2022 to 2025$1,602,868August 4, 2022April 30, 2027PFEIFER, BLAINE A.reporter.nih.gov
Inflammatory mechanisms responsible for the development of multiple organ dysfunction in pediatric patients following allogeneic blood and marrow transplantation (BMT).NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,598,857February 1, 2020January 31, 2026COOKE, KENNETH Rreporter.nih.gov
Novel Biamyxins targeting multidrug resistant Gram-negative bacterial infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,596,741July 2, 2024June 30, 2029ZHAO, YANANreporter.nih.gov
Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) StudyNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,595,582September 15, 2019July 31, 2025HUANG, LAURENCEreporter.nih.gov
Development of RespiraClear for targeted mucosal treatment of RSV infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,549,957August 19, 2019April 30, 2024CONE, RICHARDreporter.nih.gov
Acquired CFTR Dysfunction in Alcohol-related Lung PathologyNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$1,544,404January 1, 2020December 31, 2024RAJU, S.VAMSEEreporter.nih.gov
Acidosis in pulmonary endothelial injury and repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,540,000February 1, 2022January 31, 2027LEE, JI YOUNGreporter.nih.gov
Structure-function analysis of type IVB secretion systemsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,535,493June 10, 2019May 31, 2025CAPARON, MICHAEL G.reporter.nih.gov
1/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)NIHNational Heart, Lung, and Blood Institute2025$1,535,439September 15, 2025December 31, 2026WANG, HENRY E.reporter.nih.gov
Defective Zn Homeostasis impairs host defense against pneumococcal pneumoniaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,534,270December 22, 2021November 30, 2026KNOELL, DAREN LEEreporter.nih.gov
Fibrin in the Infected LungNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,530,164February 15, 2024January 31, 2028MIZGERD, JOSEPH Preporter.nih.gov
Targeting ABL kinases to regulate epithelial cell plasticity and regeneration following injuryNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,520,108June 1, 2020April 30, 2024PENDERGAST, ANN MARIEreporter.nih.gov
Serological Biomarkers for CoccidioidomycosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,518,970June 7, 2021May 31, 2026MAGEE, D MITCHELLreporter.nih.gov
Uncovering and understanding the many functions of ICAM-1 in the lungs during homeostasis and innate immune responsesNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,518,050August 26, 2024May 31, 2028DOERSCHUK, CLAIRE Mreporter.nih.gov
E3 Ligase-Mediated Immunosuppression in Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,507,608February 1, 2010June 30, 2026MALLAMPALLI, RAMA Kreporter.nih.gov
Identifying host and viral correlates for coronavirus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,493,658June 15, 2020May 31, 2025JOHNSON, BRYAN Areporter.nih.gov
Impact of Heightened UPR Activation on Inflammasome Responses to Influenza and Secondary Streptococcus pneumoniae Infection in Aged LungNIHNational Institute on Aging2021 to 2022$1,491,600May 1, 2018April 30, 2024STOUT DELGADO, HEATHER WINONAreporter.nih.gov
Novel coenzyme Q6 variant reveals non-immune determinants of survival during pneumococcal sepsisNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,481,057August 26, 2024July 31, 2028MORLEY, SHARON CELESTEreporter.nih.gov
Complement-mediated anti-pneumococcal functions of C-reactive proteinNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,480,000February 5, 2020January 31, 2026SINGH, SANJAY KUMARreporter.nih.gov
Airway Prevotella enhance innate immune-mediated protection against lung infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,475,007March 20, 2023February 29, 2028CLARK, SARAH Ereporter.nih.gov
A rationally-designed, live-attenuated RSV vaccine for the elderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,474,810August 16, 2017June 30, 2025MUELLER, STEFFENreporter.nih.gov
Reducing Infection Susceptibility by Immune Function Restoration in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,459,520July 1, 2020June 30, 2025SCHWAB, JANreporter.nih.gov
Immunotherapy of KPC InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,459,263August 1, 2020July 31, 2025KOLLS, JAY Kreporter.nih.gov
Soluble adenylyl cyclases in lung endothelial tauopathyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,451,396March 20, 2023February 28, 2027STEVENS, TROYreporter.nih.gov
Inflammatory Organ Injury after Pneumonia-Derived SepsisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,430,432July 1, 2024May 31, 2029JEYASEELAN, SAMITHAMBYreporter.nih.gov
NK cell inflammation resolution circuits in pediatric RSV infectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,426,494December 1, 2023November 30, 2028DUVALL, MELODY G.reporter.nih.gov
Mechanisms of actin cytoskeleton modulation by PneumovirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,425,119June 1, 2018May 31, 2024DUTCH, REBECCA E.reporter.nih.gov
Antibody mediated immunity against Klebsiella pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,424,123December 1, 2023October 31, 2028HARRIS, JASON Breporter.nih.gov
Lung-resident antibacterial heterotypic immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,423,673July 1, 2015June 30, 2025MIZGERD, JOSEPH Preporter.nih.gov
Surprising Efficacy of Discounted Antibiotics vs. MDR Gram-Negative Pathogens Occurring Through Innate Immune SensitizationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,422,000August 1, 2020July 31, 2025NIZET, VICTORreporter.nih.gov
Airway metabolites shape susceptibility to pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,408,116April 1, 2024March 31, 2028PRINCE, ALICE Sreporter.nih.gov
Messenger RNA capping and methylation in pneumovirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,407,102December 1, 2010January 31, 2025LI, JIANRONGreporter.nih.gov
Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,369,933November 1, 2022October 31, 2028MOUSA, JARRODreporter.nih.gov
Unique ADP-ribosylating and vacuolating properties of Mycoplasma pneumoniae CARDS toxin trigger airway inflammation and disease progressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,368,330March 1, 2019February 28, 2026KANNAN, THIRUMALAI RENGASAMYreporter.nih.gov
Understanding hypermucoviscosity in KlebsiellaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,358,649July 16, 2020September 30, 2024MILLER, VIRGINIA Lreporter.nih.gov
Vaccine immunity and inflammation in the aging person living with HIVNIHNational Institute on Aging2024 to 2025$1,337,478July 15, 2024June 30, 2029FROSCH, ANNE ELIZABETH PARKERreporter.nih.gov
Epidemiology, transmission and immunology of COVID-19 in nursing home residentsNIHNational Institute of Allergy and Infectious Diseases2021$1,332,423July 23, 2020November 30, 2023CANADAY, DAVID Hreporter.nih.gov
Molecular mechanism of cardiac inflammation and dysfunction in Pseudomonas aeruginosa infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,319,211July 1, 2019June 30, 2025RAJARAM, MURUGESANreporter.nih.gov
Emerging methods and applications for test-negative studies of of infectious disease interventionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,313,010July 17, 2020June 30, 2025JEWELL, NICHOLAS Preporter.nih.gov
Immunotherapy for acute lung injury secondary to influenzaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,310,316April 1, 2020March 31, 2025KNIGHT III, PAUL Rreporter.nih.gov
Cell surface biogenesis in Streptococcus pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,290,258January 1, 2019December 31, 2024RUDNER, DAVID Zreporter.nih.gov
Novel strategies to mitigate cardiac damage and dysfunction following invasive pneumococcal diseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,289,472May 25, 2024June 1, 2025LAL, HINDreporter.nih.gov
Intersection of Severe Respiratory Infection and Viral LatencyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,280,794June 12, 2024April 30, 2029STEED, ASHLEYreporter.nih.gov
A Regulatory Cascade that Controls Pneumococcal Capsule BiosynthesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,270,445August 23, 2019July 31, 2024ULIJASZ, ANDREW Treporter.nih.gov
Developmental Exposures to Arsenic: Pneumonia, Immunity, and Microbiomes (DEAPIM)NIHNational Institute of Environmental Health Sciences2021 to 2022$1,248,392March 10, 2021July 31, 2022PARVEZ, MUHAMMAD Freporter.nih.gov
Glypicans in Bacterial Lung InfectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,247,722April 1, 2024March 31, 2028PARK, PYONG WOOreporter.nih.gov
Mechanisms of hypervirulent Klebsiella pneumoniae gastrointestinal colonization and disseminationNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,240,075June 14, 2023May 31, 2025ZAFAR, MUHAMMAD AMMARreporter.nih.gov
Host nutrients permit immune evasion of NKT cell anti-bacterial responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,230,778January 17, 2018December 31, 2022KRONENBERG, MITCHELLreporter.nih.gov
Immune signatures of vaccine responses in children with sickle cell diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,228,468December 1, 2023October 31, 2028YILDIRIM, INCI BURCINreporter.nih.gov
Mitochondrial metabolism controls alveolar epithelial cell fateNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,227,550September 1, 2024August 31, 2029HAN, SEUNGHYEreporter.nih.gov
Deciphering the Role of Rgg in the Pneumococcal Signaling, Colonization and Virulence PortfolioNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,213,672May 23, 2019April 30, 2025HILLER, NATALIA LUISAreporter.nih.gov
C-terminal proteolysis in the Pseudomonas aeruginosa cell envelopeNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,212,063January 1, 2018December 31, 2024DARWIN, ANDREW J.reporter.nih.gov
Analyzing Adult Pneumococcal Vaccination Implementation in the UnderservedNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,185,730June 1, 2020May 31, 2025SMITH, KENNETH Jreporter.nih.gov
The role of hepoxilin A3 in neutrophil breach of the Infected airway mucosa.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,184,750February 8, 2012May 31, 2024HURLEY, BRYAN Preporter.nih.gov
Macrophage Signaling Pathways in Acute Lung Injury and ResolutionNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,180,500March 1, 2019February 29, 2024MANICONE, ANNE M.reporter.nih.gov
Trafficking and function of macrophage subpopulations within the lung microenvironment during pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,171,522January 1, 2019December 31, 2024DOERSCHUK, CLAIRE Mreporter.nih.gov
Innate Immunity in Lung Infection-induced SepsisNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$1,170,976June 1, 2018May 31, 2025JEYASEELAN, SAMITHAMBYreporter.nih.gov
Persistent Post-Viral State of Bacterial Pneumonia Susceptibility and Severity in Down SyndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,166,250June 1, 2019May 31, 2024YEAGER, MICHAEL E.reporter.nih.gov
The MUltidimenSional phenotyping In Critical care (MUSIC) Consortium: A pathway to precision medicine at the bedsideNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,162,536May 1, 2023April 30, 2029WARE, LORRAINE Breporter.nih.gov
Synergistic control of acute respiratory pathogens by bacteriophage and the innate immune responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,156,797August 22, 2019January 1, 2024WEITZ, JOSHUAreporter.nih.gov
Pathogenic role of IL-17 response in Streptococcus pneumoniae nasopharyngeal pathogenesis during an influenza virus co-infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,152,158December 3, 2019November 30, 2025KHAN, NADEEMreporter.nih.gov
Protein Transport Across Membrane by Bacterial PathogensNIHNational Institute of General Medical Sciences2023 to 2025$1,149,661July 7, 2023April 30, 2028DURIE, CLARISSA LYNNreporter.nih.gov
Defining the Role of the Plasminogen Activator Protease in the Early Events that Establish Primary Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,149,651May 1, 2021July 31, 2024PECHOUS, ROGER Dreporter.nih.gov
Colorado APS Clinical CenterNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,144,687May 1, 2023April 30, 2029MOSS, MARCreporter.nih.gov
Phenotyping ARDS, Pneumonia, and Sepsis over time to elucidate shared and distinct trajectories ofillness and recoveryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,144,421May 1, 2023April 30, 2029MEYER, NUALA JENNINGSreporter.nih.gov
Mechanisms of host protection against pathogen-associated proteases in acute lung injuryNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,142,264August 1, 2017December 31, 2022LEE, JANET SOJUNGreporter.nih.gov
Great Lakes Clinical Center of the Acute Respiratory Distress Syndrome, Pneumonia and Sepsis (APS) ConsortiumNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,140,945May 1, 2023April 30, 2029HYZY, ROBERT Creporter.nih.gov
The Intermountain West-Atlantic Center (InterACT) for the APS Phenotyping ConsortiumNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,133,343May 1, 2023April 30, 2029BROWN, SAMUEL MORRISreporter.nih.gov
Human B1-like Cells and Pneumococcal Defense in the ElderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,132,500February 1, 2019January 31, 2025ROTHSTEIN, THOMAS Lreporter.nih.gov
Sex Determines Age-related Changes in the Repertoire and Function of Natural Antibodies Protective against Streptococcus pneumoniae with Increasing AgeNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,132,500September 21, 2020August 31, 2024HOLODICK, NICHOL ELIZABETHreporter.nih.gov
The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,127,000March 20, 2024February 28, 2029WANG, YUXINreporter.nih.gov
Protecting Endogenous Recovery from the "Infectious Insult" in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,121,721September 20, 2024August 31, 2029FILOUS, ANGELA Rreporter.nih.gov
Atlas of efflux and permeation determinants to advance antibacterial therapeutic discoveryNIHNational Institute of Allergy and Infectious Diseases2025$1,120,070July 21, 2025June 30, 2030ZGURSKAYA, HELEN Ireporter.nih.gov
Molecular Phenotyping of ARDS, Pneumonia, and Sepsis using Latent Class Analysis and Metagenomic SequencingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,118,088May 1, 2023April 30, 2029CALFEE, CAROLYNreporter.nih.gov
Mechanisms of host protection against pathogen-associated proteases in acute lung injuryNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,115,035September 1, 2016August 31, 2025LEE, JANET SOJUNGreporter.nih.gov
Influenza regulation of epithelial pneumococcal host defense.NIHNational Heart, Lung, and Blood Institute2021 to 2023$1,113,750September 10, 2020August 31, 2025HARROD, KEVIN Sreporter.nih.gov
Respiratory Syncytial Virus Targeting of the Human Airway EpitheliumNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,109,490December 1, 2011December 31, 2024PEEPLES, MARK E.reporter.nih.gov
Developing a Novel E3 Ligase based Anti-inflammatory for ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,102,297February 1, 2022January 31, 2025MALLAMPALLI, RAMA Kreporter.nih.gov
Control of Influenza Infection by Lipid Mediators and MacrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,099,522January 10, 2018December 31, 2024HAHN, YOUNG S.reporter.nih.gov
The role of circadian clock proteins in innate and adaptive immunityNIHNational Institute of General Medical Sciences2023 to 2025$1,096,430September 26, 2022July 31, 2026ROSENGART, MATTHEW RANDALLreporter.nih.gov
Regulation of Legionella pneumophila pathogenesis by the central eukaryotic metabolic checkpoint kinase Mechanistic Target of Rapamycin (MTOR)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,095,000February 11, 2019January 31, 2025IVANOV, STANIMIR STEFANOVreporter.nih.gov
Lung-derived complement in pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,073,597May 19, 2023April 30, 2028KULKARNI, HRISHIKESH SATISHreporter.nih.gov
2/1 Arrest Respiratory Failure due to Pneumonia (ARREST PNEUMONIA)NIHNational Heart, Lung, and Blood Institute2021 to 2023$1,068,366September 15, 2019August 31, 2025DESAI, MANISHAreporter.nih.gov
CD4+ T cell Immunity in the Respiratory TractNIHNational Heart, Lung, and Blood Institute2025$1,063,324June 5, 2025May 31, 2032KOLLS, JAY Kreporter.nih.gov
Broad spectrum antibacterials selectively targeting an un-drugged site on the ribosomeNIHNational Institute of Allergy and Infectious Diseases2021$1,045,564June 20, 2017April 30, 2023TESTA, CHARLESreporter.nih.gov
The BLAAST Trial: Bangladesh Lung Auscultation AI for Antibiotic Stewardship Randomized Controlled TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,038,588September 1, 2024May 31, 2029MCCOLLUM, ERIC DOUGLASSreporter.nih.gov
Controlling bactermic pneumococcal pneumonia with synthetic dominant-negative competence peptidesNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,023,618April 1, 2019March 31, 2024LAU, GEE Wreporter.nih.gov
Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods ApproachNIHNational Institute on Aging2022 to 2025$1,018,845September 15, 2022June 30, 2027BUCK, KATHERINE HUNOLDreporter.nih.gov
Development of IN-003PI as passive immunization against human metapneumovirus infectionNIHNational Institute of Allergy and Infectious Diseases2025$1,013,468September 1, 2025July 31, 2028HUTCHINS, JEFF Treporter.nih.gov
Development of VLP vaccine for RSVNIHNational Institute of Allergy and Infectious Diseases2021$1,000,000February 15, 2014February 28, 2024BLANCO, JORGE Creporter.nih.gov
A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2025$1,000,000January 1, 2022August 31, 2028HARDING, CHRISTIANreporter.nih.gov
Influence of polysialic acid on leukocyte migrationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$999,737June 1, 2018May 31, 2024STAMATOS, NICHOLAS MILTONreporter.nih.gov
Therapeutic Antibody for RSV IIBNIHNational Institute of Allergy and Infectious Diseases2021$997,704February 1, 2016November 30, 2021KAUVAR, LAWRENCE MICHAELreporter.nih.gov
Bacterial Cell Wall Composition and the Influence of AntibioticsNIHNational Institute of General Medical Sciences2021 to 2023$997,488September 1, 2016May 31, 2025CEGELSKI, LYNETTE Sreporter.nih.gov
In vivo dose finding for IN-002 in neonatal lambs for inhaled immunotherapy of RSVNIHNational Institute of Allergy and Infectious Diseases2021$995,652August 20, 2018November 30, 2022CONE, RICHARDreporter.nih.gov
LncRNA regulates lung inflammationNIHNational Heart, Lung, and Blood Institute2021 to 2022$983,168September 1, 2019June 30, 2025JIN, YANGreporter.nih.gov
MycoMEIA - Urine Diagnostic for AspergillosisNIHNational Institute of Allergy and Infectious Diseases2021$976,576March 8, 2021February 28, 2023MARR, KIEREN A.reporter.nih.gov
The role of sex in the life cycle and transmission of PneumocystisNIHNational Heart, Lung, and Blood Institute2021 to 2022$965,843February 1, 2019January 31, 2024CUSHION, MELANIE Treporter.nih.gov
The impact of dietary zinc deficiency on innate immunity to lung infectionNIHNational Heart, Lung, and Blood Institute2021 to 2023$954,119February 1, 2021January 31, 2025PALMER, LAUREN DISTERHOFTreporter.nih.gov
Preclinical Pulmonary Fibrosis, an opportune rare disease cohortNIHNational Heart, Lung, and Blood Institute2021$944,445August 1, 2020July 31, 2022SCHWARTZ, DAVID ALBERTreporter.nih.gov
Role of ERK1/2 signaling in SARS-CoV-2 -induced dysregulated immunity and lung pathology.NIHNational Heart, Lung, and Blood Institute2024 to 2025$930,578September 6, 2024June 30, 2029CHANNAPPANAVAR, RUDRAGOUDAreporter.nih.gov
The Role of Sex Dimorphism in Post-TBI Bacterial PneumoniaNIHNational Institute of General Medical Sciences2021 to 2022$928,637September 21, 2018August 31, 2025WAGENER, BRANT Mreporter.nih.gov
Endolysins as tools to eradicate pneumococcal biofilms and development of protective immunityNIHNational Institute of Allergy and Infectious Diseases2023$901,010December 9, 2022November 30, 2023GONZALEZ-JUARBE, NORBERTOreporter.nih.gov
Predictive Modeling of Influenza-Pneumococcal CoinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$885,870July 1, 2018June 30, 2024SMITH, AMBER Mreporter.nih.gov
Enhancing neutrophil function in neutropenia-related pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2022$885,000August 1, 2009April 30, 2024LUO, HONGBO Rreporter.nih.gov
Dissecting the host-plasmid interplay to unravel the spread of ESBL-producing K. pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2025$874,998August 13, 2025June 30, 2030KREISWIRTH, BARRY NEALreporter.nih.gov
Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs’NIHNational Institute of Allergy and Infectious Diseases2022 to 2023$860,629June 21, 2022August 18, 2023RAO, GAURI Greporter.nih.gov
Pediatric Recovery After Sepsis Treatment in the Pediatric Intensive Care UnitNIHNational Institute of General Medical Sciences2022 to 2025$859,700September 1, 2022August 31, 2026PERRY-EADDY, MALLORY Areporter.nih.gov
Predisposition for Lung Injury in Sepsis SurvivalNIHNational Heart, Lung, and Blood Institute2021 to 2025$847,800May 1, 2021April 30, 2026DENSTAEDT, SCOTT JOHNreporter.nih.gov
Development of neonatal innate lung defenses is dependent on gastrointestinal commensal bacteriaNIHNational Heart, Lung, and Blood Institute2021 to 2022$835,296September 1, 2018August 31, 2024DESHMUKH, HITESHreporter.nih.gov
The NF-kappaB modulator PDLIM2 as an intrinsic checkpoint of alveolar macrophages critical for lung innate immunity, inflammation and diseasesNIHNational Heart, Lung, and Blood Institute2025$829,998April 1, 2025January 31, 2029QU, ZHAOXIAreporter.nih.gov
Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$828,509November 1, 2022November 30, 2023MOUSA, JARRODreporter.nih.gov
Targeting Angiopoietin-like 4 (ANGPTL4) in Severe Community Acquired PneumoniaNIHNational Heart, Lung, and Blood Institute2025$827,909April 4, 2025January 31, 2029BHATRAJU, PAVAN KUMARreporter.nih.gov
New genetic models for C5a receptorsNIHNational Heart, Lung, and Blood Institute2021 to 2022$825,000July 1, 2018June 30, 2024BOSMANN, MARKUSreporter.nih.gov
Beta-Lactamase Inhibitors Sensitize Multidrug-Resistant Gram-negative Pathogens to Innate Immune ClearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$820,829April 1, 2020March 31, 2026ULLOA, ERLINDA ROSEreporter.nih.gov
Lung vascular ILC3 subpopulation in anti-bacteria immunity and vasculature regenerationNIHNational Heart, Lung, and Blood Institute2025$814,387August 1, 2025April 30, 2029HUANG, YUEFENGreporter.nih.gov
Mechanisms of regulatory T-cell mediated endothelial repair following viral pneumonia in aged hostsNIHNational Heart, Lung, and Blood Institute2021 to 2025$805,882September 20, 2021August 31, 2026MORALES-NEBREDA, LUISAreporter.nih.gov
The oxidation of heme-carrying proteins in the pathophysiology of pneumococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$805,442November 20, 2023October 31, 2028VIDAL, JORGE EUGENIOreporter.nih.gov
Pulmonary gamma-delta T cells in lung infectionNIHNational Heart, Lung, and Blood Institute2021 to 2025$804,060June 15, 2021May 31, 2027WRIGHT, SHELTON WILEYreporter.nih.gov
Optimizing Medications and Lung Health in People with HIV through Pharmacist-led Proactive E-Consults (OPTIMIZE Lung-HIV)NIHNational Heart, Lung, and Blood Institute2025$803,801August 15, 2025May 31, 2030CROTHERS, KRISTINA ANNEreporter.nih.gov
Protecting Patients with Glomerular Disease from Vaccine-Preventable InfectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$795,246February 15, 2022January 31, 2027GLENN, DOREYreporter.nih.gov
Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - Prevent 2 StudyNIHNational Heart, Lung, and Blood Institute2021$793,344June 1, 2020May 31, 2022TREGGIARI, MIRIAMreporter.nih.gov
Identifying Novel Roles and the Therapeutic Potential of the Thrombin Receptor Protease Activated Receptor-1 (PAR1) in Lung Lymphatic Function and Acute Respiratory Distress SyndromeNIHNational Heart, Lung, and Blood Institute2025$791,503September 15, 2025June 30, 2029REED, HASINA OUTTZreporter.nih.gov
Elucidating the genotypic determinants and phenotypic effects of polymyxin resistance in Klebsiella pneumoniae utilizing CRISPR-Cas9NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$769,824July 1, 2020June 30, 2026MCCONVILLE, THOMAS HOWEreporter.nih.gov
Innate immunity and inflammatory response of macrophages to Legionella infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$765,106September 14, 2018August 31, 2024ABU KWAIK, YOUSEF Areporter.nih.gov
Migration and resolution, lung microenvironment and mechanisms: examining the diverse responses of neutrophils during S. pneumoniae pneumonia and acute lung injuryNIHNational Heart, Lung, and Blood Institute2025$759,983May 15, 2025February 28, 2029DOERSCHUK, CLAIRE Mreporter.nih.gov
Rational design of a unique vaccine for emerging pandemic coronavirusesNIHNational Institute of Allergy and Infectious Diseases2025$755,225December 6, 2024November 30, 2029QIAO, LIANGreporter.nih.gov
Putting Implementation into context to advance the management of mechanically ventilated patients.NIHNational Heart, Lung, and Blood Institute2025$748,970August 15, 2025May 31, 2029KERLIN, MEETA PRASADreporter.nih.gov
Engineering a diagnostic platform for rapid breath-based respiratory pathogen identification and treatment monitoringNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$747,000July 1, 2019June 30, 2025CHAN, LESLIEreporter.nih.gov
Refining our understanding of antimicrobial peptide mediated disruption of the Klebsiella pneumoniae capsuleNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$747,000August 24, 2021March 31, 2027FLEEMAN, RENEEreporter.nih.gov
Mechanisms of GM-CSF-mediated metabolic regulation of monocyte function for control of pulmonary infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$747,000August 5, 2023July 31, 2026LIU, XINreporter.nih.gov
Lung epithelial cell reprogramming by CD4 T cellsNIHNational Heart, Lung, and Blood Institute2023 to 2025$746,997April 1, 2023March 31, 2026SHENOY, ANUKUL Treporter.nih.gov
Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - Prevent 2 StudyNIHNational Heart, Lung, and Blood Institute2022$743,776September 19, 2022May 31, 2026TREGGIARI, MIRIAMreporter.nih.gov
The Roles of LPS-Binding Protein Vascular Peroxidase-1 in Innate ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$742,500January 4, 2019December 31, 2023CHENG, GUANGJIEreporter.nih.gov
Impact of Diet Induced Obesity on Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$725,760January 15, 2022January 17, 2025PLATAKI, MARIAreporter.nih.gov
Preclinical development of a synthetic lung surfactant dry powder aerosol for acute respiratory distress syndrome patients receiving different modes of ventilation supportNIHNational Heart, Lung, and Blood Institute2022$719,373September 22, 2022June 30, 2023LONGEST, P. WORTHreporter.nih.gov
Pulmonary neuroimmune determinants of immunoglobulin production against pneumoniaNIHNational Heart, Lung, and Blood Institute2025$718,661August 1, 2025April 30, 2030JENDZJOWSKY, NICHOLASreporter.nih.gov
LOX-1 as a protective countermeasure in response to lung infectionNIHNational Heart, Lung, and Blood Institute2022$703,500September 19, 2022June 5, 2023QUINTON, LEEreporter.nih.gov
Characterization of Rifabutin Therapy Against Antibiotic-Resistant BacteriaNIHNational Institute of Allergy and Infectious Diseases2021$696,618August 10, 2018July 31, 2023LUNA, BRIAN MICHAELreporter.nih.gov
2/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)NIHNational Heart, Lung, and Blood Institute2025$688,047September 1, 2025August 31, 2031DURKALSKI, VALERIE Lreporter.nih.gov
Nosocomial pneumonia impairs the cerebrovasculatureNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$684,527May 16, 2024May 2, 2025NELSON, AMY Rreporter.nih.gov
Targeting Estrogenic pathways in Tregs to promote ARDS resolution - 5R01HL163881NIHNational Heart, Lung, and Blood Institute2025$684,280August 15, 2025May 31, 2027D'ALESSIO, FRANCO RAFAELreporter.nih.gov
Zinc intervention in prevention of pneumonia in elderlyNIHNational Heart, Lung, and Blood Institute2021 to 2022$679,500July 1, 2021June 30, 2024PANDA, ALEXANDERreporter.nih.gov
Extending neutrophil survival in neutropenia-related pneumoniaNIHNational Heart, Lung, and Blood Institute2025$676,748July 1, 2025March 31, 2029LUO, HONGBO Rreporter.nih.gov
The effect of household air pollution on lung function growth in infants with pneumonia in sub-Saharan Africa.NIHNational Institute of Environmental Health Sciences2021 to 2024$670,862March 14, 2024February 28, 2025MOSCHOVIS, PETER Preporter.nih.gov
The role of HMGB1 in the lung response to bacterial injuryNIHNational Heart, Lung, and Blood Institute2025$656,988August 1, 2025April 30, 2030MESSER, JEANNETTE SOPHIAreporter.nih.gov
Full Spectrum Cell Sorter with Imaging Enhancement for Boston University Flow Cytometry Core FacilityNIHOffice of the Director, National Institutes of Health2025$656,148April 15, 2025April 14, 2026BELKINA, ANNAreporter.nih.gov
Intrapulmonary itaconate as a host-protective metabolite during ER Stress and Klebsiella pneumoniae infectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$642,944April 1, 2022March 31, 2027SUBER, TOMEKA Lreporter.nih.gov
SARS-CoV-2 tropism in the brain and its relationship to COVID-19 pathogenesisNIHNational Heart, Lung, and Blood Institute2021$642,597September 25, 2021August 31, 2023YAKOUB, ABRAAM M.reporter.nih.gov
Impaired Pneumococcal Antibody Function and Exacerbations of Chronic Obstructive Pulmonary DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$642,128January 1, 2022December 31, 2026LAFON, DAVID CARDYreporter.nih.gov
CD38, T cells and post viral lung sequelae during agingNIHNational Institute on Aging2025$639,740December 15, 2024November 30, 2029SUN, JIEreporter.nih.gov
Repertoire studies of human antibodies to RSV and MPV FNIHNational Institute of Allergy and Infectious Diseases2021$621,866September 6, 2018August 31, 2023JARDETZKY, THEODORE Sreporter.nih.gov
Eosinophils as Effectors of Antibacterial Immunity in the LungsNIHNational Heart, Lung, and Blood Institute2024$615,455September 1, 2024June 30, 2028SAMARASINGHE, AMALIreporter.nih.gov
A redox-sensitive switch in the macrophage nucleus regulates acute phaseinflammatory injuryNIHNational Heart, Lung, and Blood Institute2025$613,814June 1, 2022May 31, 2027BONINI, MARCELO G.reporter.nih.gov
Eosinophils as Effectors of Antibacterial Immunity in the LungsNIHNational Heart, Lung, and Blood Institute2025$613,501September 1, 2024June 30, 2028SAMARASINGHE, AMALI Ereporter.nih.gov
Lung Macrophage Memory Development and Responses in Secondary Pneumonia and SepsisNIHNational Institute of Allergy and Infectious Diseases2021$610,868August 27, 2021July 31, 2025MISHRA, BIBHUTI BHUSANreporter.nih.gov
Host control mechanisms against K. pneumoniae infection in the lungsNIHNational Heart, Lung, and Blood Institute2021$603,934April 1, 2018March 31, 2024CHEN, KONGreporter.nih.gov
Optimize Formulation of VSA AdjuvantNIHNational Institute of Allergy and Infectious Diseases2022$600,000July 5, 2022July 5, 2024CLEMENTS, DAVIDreporter.nih.gov
Formulation of a prophylactic vaccine against Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$599,999March 16, 2022February 28, 2025NAGEL, AARON Creporter.nih.gov
Mechanisms of Klebsiella pneumoniae gastrointestinal colonizationNIHNational Institute of Allergy and Infectious Diseases2025$599,768June 14, 2023May 31, 2029ZAFAR, MUHAMMAD AMMARreporter.nih.gov
Pn3Pase as an Effective Enzyme Therapeutic for Streptococcus Pneumoniae type 3 InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$598,900July 9, 2021June 30, 2024AVCI, FIKRI Yreporter.nih.gov
Development of FosA Inhibitors to Potentiate Fosfomycin Activity in Gram-Negative PathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$598,124August 15, 2022June 30, 2024WROBEL, JAY EDWARDreporter.nih.gov
Development of Broad-Spectrum Cyclic Amphiphilic Peptides against Multidrug-Resistant BacteriaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$596,643August 18, 2022July 31, 2025KAZEMINY, ASSADreporter.nih.gov
Development of Coccidioides Cytokine Release AssayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$596,247March 1, 2021February 28, 2023WHEAT, LAWRENCE JOSEPHreporter.nih.gov
A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$593,112January 1, 2022December 31, 2024HARDING, CHRISTIANreporter.nih.gov
Targeted delivery of novel miRNA-based therapeutics for pneumonia-induced acute lung injuryNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$583,152September 8, 2022August 31, 2025AKERLEY, BRIANreporter.nih.gov
Host factors influencing early clearance of Streptococcus pneumoniae from the middle ear following invasion from the nasopharynxNIHNational Institute on Deafness and Other Communication Disorders2022 to 2024$583,125February 1, 2022July 31, 2025CLARK, SARAH Ereporter.nih.gov
Individualizing Steroid Use in Pneumonia (Supplement)NIHNational Heart, Lung, and Blood Institute2023 to 2025$582,229June 1, 2023July 31, 2026ODEYEMI, YEWANDEreporter.nih.gov
Patient-Oriented Research on Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$549,502July 10, 2013January 31, 2025HAUSER, ALAN Rreporter.nih.gov
Lung-derived complement in pneumoniaNIHNational Heart, Lung, and Blood Institute2025$546,742July 8, 2025April 30, 2028KULKARNI, HRISHIKESH SATISHreporter.nih.gov
Targeting TLR Signaling Pathways to Blunt Pathogen-mediated Acute Lung InjuryNIHNational Institute of Allergy and Infectious Diseases2021$544,376February 10, 2017January 31, 2023VOGEL, STEFANIE N.reporter.nih.gov
Genetic Analysis of Legionella Phagosome TraffickingNIHNational Institute of Allergy and Infectious Diseases2021$544,169August 1, 2017July 31, 2023ROY, CRAIG R.reporter.nih.gov
Netosis in Trauma mediated Acute Lung InjuryNIHNational Institute of General Medical Sciences2021 to 2023$540,344September 14, 2021July 31, 2024LEONARD, JENNIFERreporter.nih.gov
Consequences of Direct Viral-Bacterial InteractionsNIHNational Institute of Allergy and Infectious Diseases2021$531,058July 20, 2021June 30, 2023ROSCH, JASON W.reporter.nih.gov
Rational design of an adhesin-based pneumococcal vaccine targeting colonizationNIHNational Institute of Allergy and Infectious Diseases2025$528,735September 17, 2020August 31, 2028THORNTON, JUSTIN Areporter.nih.gov
Defining the Role of the Plasminogen Activator Protease in the Early Events that Establish Primary Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$525,035May 1, 2021April 30, 2027PECHOUS, ROGER Dreporter.nih.gov
A 3D human tissue-engineered lung model to study immune responses to Respiratory Syncytial VirusNIHNational Institute of Biomedical Imaging and Bioengineering2021$517,917September 20, 2018June 30, 2024KOVATS, SUSANreporter.nih.gov
ENaC-α mediates lung fluid clearance and capillary barrier function in pneumoniaNIHNational Heart, Lung, and Blood Institute2021$515,730July 1, 2018June 30, 2023LUCAS, RUDOLFreporter.nih.gov
Inflammasomes: Regulation and Function in Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2021$508,492July 1, 1996March 31, 2023CHOI, MARY Ereporter.nih.gov
Elucidating the Sexual Cycle of HIV/AIDS-Related Pneumocystis PneumoniaNIHNational Heart, Lung, and Blood Institute2025$508,041August 1, 2025May 31, 2029SMULIAN, ALAN GEORGEreporter.nih.gov
The Function and Potential Application of Extracellular Vesicle Derived Clara Cell Protein 16 in Gram-negative Bacterial PneumoniaNIHNational Heart, Lung, and Blood Institute2023$501,482September 1, 2023August 31, 2025ZHANG, DUOreporter.nih.gov
Establishing Mechanisms of LOX-1-Dependent Immune Regulation During PneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$498,000July 22, 2024June 30, 2027KORKMAZ, FILIZreporter.nih.gov
Understanding the immunometabolic response to Klebsiella pneumonia infectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$497,998April 1, 2024March 31, 2027WONG FOK LUNG, TANIAreporter.nih.gov
Lincenc1 regulates the lipopolysaccharide-induced inflammatory response in macrophagesNIHNational Heart, Lung, and Blood Institute2021 to 2022$495,100June 20, 2020May 31, 2024ZHANG, DUOreporter.nih.gov
Assessing Klebsiella pneumoniae invasion of the intact gut microbiomeNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$493,654August 5, 2021March 31, 2025VORNHAGEN, JAYreporter.nih.gov
IFN/SOCS1 signaling during post-influenza bacterial infectionNIHNational Institute of Allergy and Infectious Diseases2025$489,965September 1, 2025August 31, 2026SUN, KEERreporter.nih.gov
Unravelling the role of aDb2 as a novel complement receptor in lung injuryNIHNational Institute of Allergy and Infectious Diseases2025$489,500July 25, 2025June 30, 2027KOUTSOGIANNAKI, SOPHIAreporter.nih.gov
Invasive Pneumococcal Disease and Carriage among Children with Sickle Cell Disease in Ghana: A Post-vaccination StudyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$489,262May 12, 2022April 30, 2027SAMPANE-DONKOR, ERICreporter.nih.gov
Host Response, Lung Microbiome, and Clinical Phenotype in Hypersensitivity PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2023$487,290April 1, 2019February 29, 2024SALISBURY, MARGARET LOUISEreporter.nih.gov
Identification of RNA-binding proteins in Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$486,750April 25, 2022March 31, 2025DOVE, SIMON Lreporter.nih.gov
Integrative Multi-Scale Systems Analysis of Gene-Expression-Driven Aging MorbidityNIHNational Institute on Aging2024 to 2025$485,270September 15, 2020December 31, 2026STOEGER, THOMASreporter.nih.gov
Pulmonary Epithelial Dynamics and Innate Host DefenseNIHNational Heart, Lung, and Blood Institute2021$480,973December 7, 2017November 30, 2022MCCORMACK, FRANCIS XAVIERreporter.nih.gov
Metformin to improve immunological health and vaccine responsesNIHNational Institute on Aging2021 to 2023$478,119May 1, 2020February 28, 2025LEE, GRACE CHOIreporter.nih.gov
Impact of Pandemic Mitigation Efforts on Colonization and Transmission of Respiratory Pathogens and Antibiotic Resistance GenesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$475,750June 8, 2022May 31, 2024HOWARD, LEIGH MEREDITHreporter.nih.gov
The anatomy of T-cell mediated neutrophil recruitment during lung infectionNIHNational Institute of Allergy and Infectious Diseases2025$472,210June 23, 2025May 31, 2027QUINTON, LEEreporter.nih.gov
Features of PMN Senescence that Lead to Susceptibility to Pneumococcal InfectionNIHNational Institute on Aging2021 to 2022$469,115March 1, 2021February 29, 2024MECSAS, JOAN Creporter.nih.gov
Characterization of assembly factors for type IV secretion systemsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$466,999June 21, 2021May 31, 2024CAPARON, MICHAEL G.reporter.nih.gov
Dynactin 4 regulation of lung injuryNIHNational Heart, Lung, and Blood Institute2021$466,844January 1, 2018November 30, 2022CHEN, PETERreporter.nih.gov
Within-host diversity of Gram negative bacteria from bloodstream infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$466,480November 21, 2023October 31, 2026NGUYEN, M. HONG THIreporter.nih.gov
Antibiotic resistance among hypermutator carbapenem resistant Klebsiella pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$466,199June 21, 2022May 31, 2025NGUYEN, M. HONG THIreporter.nih.gov
Autosomal dominant OTULIN deficiency and staphylococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$466,125August 15, 2022July 31, 2024BOISSON, BERTRANDreporter.nih.gov
Risk Stratification and Decision Support to Improve Care and Outcomes in Children with PneumoniaNIHNational Institute of Allergy and Infectious Diseases2021$460,844February 7, 2017January 31, 2023WILLIAMS, DEREK J.reporter.nih.gov
Reciprocal brain-lung responses in post-stroke pneumoniaNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$460,625August 1, 2023July 31, 2025SANSING, LAUREN Hreporter.nih.gov
Pyocins as antibacterials to treat Pseudomonas aeruginosa infectionsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$458,460July 1, 2023June 30, 2025GOLDBERG, JOANNA Breporter.nih.gov
Innovative Antibiotic Combinations for Hypervirulent Klebsiella pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2025$456,911July 1, 2025June 30, 2027BULMAN, ZACKERY P.reporter.nih.gov
A novel bacteria-specific pro-photosensitizerNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$456,558March 11, 2024January 31, 2027WU, MEI Xreporter.nih.gov
Spatiotemporal interrogation of interactions of pneumolysin, pulmonary epithelium, and PMNs that result in age-associated susceptibility to Streptococcus pneumoniae diseaseNIHNational Institute of Allergy and Infectious Diseases2025$450,630August 1, 2025July 31, 2027LEONG, JOHN Mreporter.nih.gov
Urovirulence and fimbrial regulation in Klebsiella quasipneumoniaeNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$450,360August 18, 2023July 31, 2025DE NISCO, NICOLE JANELLreporter.nih.gov
Deciphering the impact of sedative choice on the dynamics of Klebsiella pneumoniae lung infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$449,200November 16, 2021October 31, 2023FREITAG, NANCY ELIZABETHreporter.nih.gov
Pulmonary Disfunction after Polysubstance Exposure: Mechanistic Identification of Inflammatory MediatorsNIHNational Institute of General Medical Sciences2022 to 2024$448,917July 8, 2022November 30, 2025SIVARAMAN, VIJAYreporter.nih.gov
Siderophores of Legionella pneumophilaNIHNational Institute of Allergy and Infectious Diseases2021$447,861July 23, 2018June 30, 2023CIANCIOTTO, NICHOLAS Preporter.nih.gov
RBC-mediated mopping of cytokines for the treatment of pneumoniaNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$446,875September 24, 2021August 31, 2023BRENNER, JACOBreporter.nih.gov
TNF and caspase-8-mediated control of Legionella pneumophila infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$446,667March 5, 2021February 29, 2024SHIN, SUNNYreporter.nih.gov
Identifying niche specific adaptations in Acinetobacter baumanniiNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$445,587March 24, 2022February 28, 2025FELDMAN, MARIOreporter.nih.gov
Origin and host adaptation of the novel canine coronavirus (CCoV-HuPn-2018) isolated from a human pneumonia patientNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$445,439August 23, 2023July 31, 2025VLASOVA, ANASTASIA NICKOLAEVNAreporter.nih.gov
Mechanisms of age-related lung inflammation in pulmonary melioidosisNIHNational Institute of Allergy and Infectious Diseases2025$445,338July 23, 2025June 30, 2027WRIGHT, SHELTON WILEYreporter.nih.gov
A Novel Mucosal Vaccine for Pseudomonas aeruginosa InfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$444,989February 1, 2022July 31, 2024ARNABOLDI, PAUL MICHAELreporter.nih.gov
Dissecting a sensory system for Legionella replication vacuole integrityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$444,172May 22, 2024March 31, 2027O'CONNOR, TAMARAreporter.nih.gov
Sex-Dependent Regulation of Host Factors Influencing SARS-CoV-2 Infection and COVID-19 DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$442,751April 15, 2022March 31, 2024ANGUERA, MONTSERRAT Creporter.nih.gov
HEMOGLOBIN-INDUCED VIRULENCE IN STREPTOCOCCUSPNEUMONIAENIHNational Institute of Allergy and Infectious Diseases2021 to 2022$441,005March 10, 2021February 29, 2024VIDAL, JORGE EUGENIOreporter.nih.gov
Effector-triggered immunity against Legionella pneumophila in dendritic cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$440,625July 5, 2023June 30, 2025SHIN, SUNNYreporter.nih.gov
Novel small-molecule inhibitors of SARS-CoV-2 proteaseNIHNational Institute of Allergy and Infectious Diseases2021$440,000December 1, 2020November 30, 2023SONG, YONGCHENGreporter.nih.gov
Microglia mediate cognitive dysfunction in elderly survivors of pneumoniaNIHNational Institute on Aging2022$440,000February 1, 2022January 31, 2025MISHARIN, ALEXANDERreporter.nih.gov
PIWIL4 and piRNAs in RSV InfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$440,000January 25, 2023August 31, 2025CASOLA, ANTONELLAreporter.nih.gov
Deciphering how the Cas2 ribonuclease non-canonically controls Legionella pneumophila thermal tolerance and virulenceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$440,000July 8, 2024May 31, 2026CIANCIOTTO, NICHOLAS Preporter.nih.gov
Microbial and Host Factors that Promote Epithelial Disruption and S. pneumoniae Transit out of the LungNIHNational Institute of General Medical Sciences2021 to 2023$439,500April 1, 2021March 31, 2025ADAMS, WALTER ISAIAHreporter.nih.gov
Rational identification of Corynebacterium strains for use as probioticsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$439,416May 16, 2022April 30, 2025SEED, PATRICK C.reporter.nih.gov
The Role of the EphA2 Receptor Kinase Pathway in Pneumocystis Pneumonia (PCP)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$437,798November 16, 2023October 31, 2025LIMPER, ANDREW Hreporter.nih.gov
Early detection and identification of ventilator associated pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2024$437,250April 15, 2023March 31, 2026CORCORAN, TIMOTHY Ereporter.nih.gov
Function of the Klebsiella pneumoniae RND efflux systemsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$436,990June 17, 2022May 31, 2025BINA, JAMES EDWARDreporter.nih.gov
Inflammation-targeted delivery of corticosteroids using genetically engineered cellular nanoparticlesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$434,500February 8, 2023March 31, 2025FANG, RONNIE Hreporter.nih.gov
Negative regulation of inflammation during Klebsiella pneumoniae infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$432,980May 11, 2021April 30, 2024TREVEJO-NUNEZ, GIRALDINAreporter.nih.gov
Use of site-specific pharmacokinetics to optimize antibiotic combinations and prevent the emergence of resistance against CRENIHNational Institute of Allergy and Infectious Diseases2021 to 2022$431,417November 24, 2020October 31, 2024SHIELDS, RYAN Kreporter.nih.gov
F-18 fluorodeoxysorbitol for detecting response of bacterial infection to treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$429,500March 16, 2021February 29, 2024NG, CHIN Kreporter.nih.gov
Susceptibility determinants to Legionella pneumophila infection in smokersNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$429,000March 18, 2021August 31, 2023AMER, AMAL Oreporter.nih.gov
Exploring protein translocation by the Legionella pneumophila Dot/Icm Type IV Section SystemNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$429,000June 11, 2021May 31, 2024OHI, MELANIE DIANEreporter.nih.gov
Small RNA based control of zinc homeostasis in Streptococcus pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$429,000May 20, 2022April 30, 2024DE LAY, NICHOLAS R.reporter.nih.gov
Capsular locus deep sequencing to study Klebsiella populationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$429,000August 22, 2023July 31, 2025BACHMAN, MICHAEL ABBOTTreporter.nih.gov
Q223R Leptin Receptor Polymorphism in Bacterial PneumoniaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$429,000December 1, 2023October 31, 2026MANCUSO, PETERreporter.nih.gov
Investigation of capsule interactions that promote antimicrobial peptide activityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$428,855March 19, 2021February 29, 2024DAVIES, BRYAN WILLIAMreporter.nih.gov
Metabolomic Prediction of Pneumonia SeverityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$427,625April 21, 2021March 31, 2024AMBROGGIO, LILLIAMreporter.nih.gov
Multi-omics of murine respiratory melioidosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$427,625August 1, 2023July 31, 2025WEST, TIMOTHY EOINreporter.nih.gov
Immune recognition of Klebsiella pneumoniae O2v1 and O2v2 O-antigen subtypesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$427,625August 1, 2023July 31, 2025ROSEN, DAVID A.reporter.nih.gov
Acinetobacter baumannii reservoirs within the hostNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$427,625June 1, 2024April 30, 2026FELDMAN, MARIOreporter.nih.gov
Elucidating the role of fimbriae in Klebsiella pneumoniae-mediated liver abscess formationNIHNational Institute of Allergy and Infectious Diseases2025$427,625July 1, 2025June 30, 2027ROWE, SARAH ELIZABETHreporter.nih.gov
Antibiotic treatment failure of Klebsiella pneumoniae liver abscessesNIHNational Institute of Allergy and Infectious Diseases2025$427,625August 1, 2025July 31, 2027ROWE, SARAH ELIZABETHreporter.nih.gov
Resolution of Diffuse Inflammatory Lung Injury in Neonatal MiceNIHNational Heart, Lung, and Blood Institute2021$426,425June 15, 2013August 31, 2023MCGRATH-MORROW, SHARON ANNreporter.nih.gov
Animal models of SARS-CoV-2 bacterial CoinfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$426,250May 16, 2022April 30, 2025XIANG, YANreporter.nih.gov
Biology of hypervirulent Klebsiella pneumoniae translocation from the gastrointestinal tractNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$426,250November 1, 2021October 31, 2024ZAFAR, MUHAMMAD AMMARreporter.nih.gov
The impact of aging and thymus regeneration on tissue-resident CD8 T cell responses to viral lung infection and vaccinationNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$426,250June 1, 2022May 31, 2025GRIFFITH, ANN VENABLESreporter.nih.gov
Mechanisms underlying adhesion and colonization in pneumococcal keratitisNIHNational Eye Institute2023$426,250August 1, 2023July 31, 2025MARQUART, MARY Ereporter.nih.gov
Role of B cells in controlling Klebsiella pneumoniae associated disease statesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$426,250May 25, 2023April 30, 2026HAAS, KAREN Mreporter.nih.gov
Targeting T3SA proteins as protective antigens against YersiniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$425,855January 24, 2023December 31, 2025PICKING, WENDY L.reporter.nih.gov
DeADP-ribosylation of host targets mediated by a bacterial effectorNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$425,526January 19, 2023December 31, 2025DAS, CHITTARANJANreporter.nih.gov
Live attenuated non-transmissible (LANT) Klebsiella pneumoniae vaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$424,875May 23, 2023April 30, 2026BALIBAN, SCOTT M.reporter.nih.gov
Impact of Dual Alcohol and Cannabis Use on LungNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$423,961August 20, 2021July 31, 2024BURNHAM, ELLEN Lreporter.nih.gov
Impact of Heightened ER Stress on NLRP3 Activation in Aged Lung during InfectionNIHNational Institute on Aging2021$423,750September 1, 2017May 31, 2023STOUT DELGADO, HEATHER WINONAreporter.nih.gov
An intranasal room stable vaccine formulation to prevent Pseudomonas aeruginosa (R21AI169691)NIHNational Institute of Allergy and Infectious Diseases2023 to 2024$423,595September 1, 2023August 31, 2025PICKING, WENDY L.reporter.nih.gov
The amyloid precursor protein protects against acute lung injuryNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$423,500August 11, 2023July 31, 2025AUDIA, JONATHON PETERreporter.nih.gov
The Pseudomonas aeruginosa virulence factor ExoU activates pyroptosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$423,500December 1, 2023October 31, 2025AUDIA, JONATHON PETERreporter.nih.gov
Addressing genetic tractability and species-specific infection biology in Chlamydia pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$420,750November 7, 2022June 30, 2025FIELDS, KENNETH Areporter.nih.gov
Recent thyme emigrants mitigate viral pulmonary pneumoniaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$420,750May 23, 2024March 31, 2026POCIASK, DEREK Areporter.nih.gov
Rethinking Legionella pneumophila type IV pili and their roles in intracellular infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$420,669June 13, 2023May 31, 2025CIANCIOTTO, NICHOLAS Preporter.nih.gov
Mucinases as Emerging Players in Legionella pneumophila PathogenesisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$420,105February 1, 2023January 31, 2025CIANCIOTTO, NICHOLAS Preporter.nih.gov
The role of PMNs and CD73 in host-resistance against S. pneumoniae / influenza A virus co-infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$419,393February 24, 2023January 31, 2026BOU GHANEM, ELSAreporter.nih.gov
Interrogation of the sRNA regulatory network mediating virulence of Streptococcus pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$419,275December 1, 2023October 31, 2026MEYER, MICHELLE MARGARETreporter.nih.gov
Macrophage Redox State in Sterilizing and Injurious InflammationNIHNational Institute of Allergy and Infectious Diseases2021$418,223April 7, 2017March 31, 2023BONINI, MARCELO G.reporter.nih.gov
PNA-STAMPs: Versatile, Potent and Targeted AntibioticsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$418,109August 1, 2024June 30, 2027HILLER, NATALIA LUISAreporter.nih.gov
Mathematical Modeling of Influenza Severity in Outbred MiceNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$418,042November 25, 2020October 31, 2023ALCORN, JOHN Freporter.nih.gov
Antibody therapy for pneumococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2021$417,500November 10, 2016October 31, 2022PIROFSKI, LIISE-ANNEreporter.nih.gov
Development and Evaluation of CRRT-Specific Precision Dosing Models to Optimize Beta-Lactam Treatment for Patients with Hospital-Acquired PneumoniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$417,308June 23, 2023May 31, 2026RHODES, NATHANIEL JAMESreporter.nih.gov
Integrated modeling of Klebsiella pneumoniae infections based on bacterial genotype, patient factors and colonization statusNIHNational Institute of Allergy and Infectious Diseases2021$417,192February 15, 2017January 31, 2023BACHMAN, MICHAEL ABBOTTreporter.nih.gov
C3 Mitigates Epithelial Injury in PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2023$416,942September 1, 2019August 31, 2025KULKARNI, HRISHIKESH SATISHreporter.nih.gov
Role of Legionella pneumophila Lvh TIVSS in virulenceNIHNational Institute of General Medical Sciences2021 to 2024$415,060August 20, 2021May 31, 2026DUBYTSKA, LIDIYAreporter.nih.gov
HMPV/RSV co-infection: effects on replication and viral spreadNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$413,248August 11, 2023July 31, 2026DUTCH, REBECCA E.reporter.nih.gov
In vitro PCLS models of PneumocystisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$407,303June 1, 2024April 30, 2027KOLLS, JAY Kreporter.nih.gov
Mechanistic triggers of excessive mucus during lung infections by bacterial volatile organic compoundsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$407,208August 25, 2023July 31, 2026LAU, GEE Wreporter.nih.gov
Supplement to "New ACE2 activator and its prodrug as novel therapeutic regents for inflammatory pulmonary diseases"NIHNational Institute of Allergy and Infectious Diseases2021$406,756April 2, 2020December 31, 2022JIA, HONGPENGreporter.nih.gov
Myeloid cell TRAF6 signaling in SARS-CoV-2-induced dysregulated lung immunityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$406,438June 1, 2024April 30, 2027CHANNAPPANAVAR, RUDRAGOUDAreporter.nih.gov
Strategies to Enhance Pneumonia Care via Intermediate Intensive Care (STEP IN)NIHNational Heart, Lung, and Blood Institute2021$403,484September 1, 2017May 31, 2022COOKE, COLINreporter.nih.gov
Development of a Molecular Toolbox for PneumocystisNIHNational Institute of Allergy and Infectious Diseases2025$402,860December 1, 2024November 30, 2027SMULIAN, ALAN GEORGEreporter.nih.gov
The vital role of T404 phosphorylation of STAT2 in post-viral bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2022$402,500September 1, 2022August 31, 2024WANG, YUXINreporter.nih.gov
Cardiomyocyte self-defense against Streptococcus pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$396,589March 7, 2023February 28, 2026ORIHUELA, CARLOS Jreporter.nih.gov
SSLs immune manipulation in S aureus colonization, infection, and a potential therapy against pneumoniaNIHNational Institute of Allergy and Infectious Diseases2025$392,409August 1, 2025July 31, 2030CHEN, CHENreporter.nih.gov
Personalizing Antimicrobial Use in Ventilator-Associated PneumoniaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$388,800June 18, 2024May 31, 2029ALBIN, OWENreporter.nih.gov
Bacteriophage-mediated microbiota modification to prevent colorectal cancer developmentNIHNational Cancer Institute2022 to 2023$387,838May 10, 2022February 28, 2025EL HADDAD, LYNNreporter.nih.gov
Electronic Cigarette Vapor Inhalation Adversely Affects Lung Cellular and Physiologic Function and Alters Systemic Inflammatory PathwaysNIHNational Heart, Lung, and Blood Institute2021$387,500April 1, 2017December 31, 2022CROTTY ALEXANDER, LAURA ELISEreporter.nih.gov
Novel antimicrobials to combat Gram-negative bacteriaNIHNational Institute of Allergy and Infectious Diseases2023$383,750August 16, 2023July 31, 2025WANG, GUANGSHUNreporter.nih.gov
Regulation of phosphodiesterases and cAMP signaling during the host-pathogen interaction in the pulmonary endotheliumNIHNational Heart, Lung, and Blood Institute2021$378,245April 1, 2018March 31, 2023RICHTER, WITO Hreporter.nih.gov
Molecular and cellular mechanism regulating innate immunity and inflammation during pattern recognition receptor activation and respiratory virus infectionNIHNational Institute of Allergy and Infectious Diseases2021$375,233June 1, 2010July 31, 2024BOSE, SANTANUreporter.nih.gov
Development of LspA Inhibitors to Treat Gram-negative Bacterial InfectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$374,000July 1, 2022June 30, 2024SUTTERLIN, HOLLY ANNreporter.nih.gov
The role of circadian clock proteins in innate and adaptive immunityNIHNational Institute of General Medical Sciences2022$373,588September 26, 2022June 30, 2023ROSENGART, MATTHEW RANDALLreporter.nih.gov
Molecular Mechanism of Lung Barrier DysfunctionNIHNational Heart, Lung, and Blood Institute2021$371,250July 1, 2018May 31, 2024DING, QIANGreporter.nih.gov
Pneumococcal dynamics in the conjugate vaccine era: Addressing unanswered questionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$368,213January 17, 2019December 31, 2023HOWARD, LEIGH MEREDITHreporter.nih.gov
Development and implementation of a pediatric AI multi-modal digital stethoscope and respiratory surveillance system in South AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$367,680August 7, 2023July 31, 2025MCCOLLUM, ERIC DOUGLASSreporter.nih.gov
Host Response and Immunity to Yersenia pestis InfectionNIHNational Institute of Allergy and Infectious Diseases2021$365,222May 8, 2017April 30, 2023ANDERSON, DEBORAH Mreporter.nih.gov
A parainfluenza virus 5 (PIV5)-based bivalent vaccine for respiratory syncytial virus (RSV) and human metapneumovirus (HMPV)NIHNational Institute of Allergy and Infectious Diseases2023 to 2024$358,875September 5, 2023August 31, 2025GINGERICH, MARIA CRISTINAreporter.nih.gov
Pathogenic role of IL-17 response in Streptococcus pneumoniae nasopharyngeal pathogenesis during an influenza virus co-infectionNIHNational Institute of Allergy and Infectious Diseases2021$357,081December 3, 2019November 30, 2024KHAN, NADEEMreporter.nih.gov
Role of epigenetic changes in intracellular survival and replication of Legionell pneumophilaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$354,650September 1, 2024August 31, 2028BANGA, SIMRANreporter.nih.gov
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia (P-RAPP)NIHNational Heart, Lung, and Blood Institute2021$353,127September 1, 2020June 30, 2022FLORIN, TODD ADAMreporter.nih.gov
Glycan-Lectin Receptor Regulation of Macrophage Maturation and Lung InnateDefenses in the Fetus and Newborn InfantNIHNational Institute of Allergy and Infectious Diseases2021$348,400July 17, 2019June 30, 2023PRINCE, LAWRENCE Sreporter.nih.gov
Alveolar organoids and metabolomic-driven cultivation of Pneumocystis speciesNIHNational Institute of Allergy and Infectious Diseases2025$344,534December 20, 2024November 30, 2027SMULIAN, ALAN GEORGEreporter.nih.gov
The Effect of Maternal Cells on Infant ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$341,450December 12, 2017July 31, 2023HARRINGTON, WHITNEY ELIZABETHreporter.nih.gov
Precision medicine approaches in the diagnosis of community-acquired pneumonia in childrenNIHNational Heart, Lung, and Blood Institute2024 to 2025$335,920July 1, 2024June 30, 2028RAMGOPAL, SRIRAMreporter.nih.gov
Preventing avoidable deaths from pneumonia by improving use of intensive careNIHNational Heart, Lung, and Blood Institute2021 to 2022$334,708August 7, 2018September 30, 2023VALLEY, THOMAS SEBASTIANreporter.nih.gov
Machine learning to predict cure in severe pneumonia episodesNIHNational Heart, Lung, and Blood Institute2024 to 2025$332,834April 1, 2024March 31, 2029GAO, CATHERINE A.reporter.nih.gov
Using Legionella-amoeba co-evolution to reveal new modes of immunity and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021$330,434July 1, 2020June 30, 2022LEVIN, TERA CATHERINEreporter.nih.gov
Multidimensional analysis of the regulatory T cell response in children with severe viral pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$326,160September 1, 2024August 31, 2029PRIGGE, ANDREWreporter.nih.gov
Microbiome-based diagnosis of pneumonia in the acute respiratory distress syndromeNIHNational Heart, Lung, and Blood Institute2021 to 2022$323,786January 22, 2018December 31, 2022KITSIOS, GEORGIOSreporter.nih.gov
A novel Th17-enhancing adjuvant and conserved antigen for protection against viral/bacterial co-infectionNIHNational Institute of Allergy and Infectious Diseases2025$308,669September 23, 2025March 31, 2027AKERLEY, BRIANreporter.nih.gov
Pulsed Focused Ultrasound (pFUS) exposures and devices for tissue permeabilization without contrast agentsNIHNational Institute of Biomedical Imaging and Bioengineering2021$306,746January 19, 2021September 18, 2021KHOKHLOVA, TATIANAreporter.nih.gov
Nasopharyngeal Microbiome and Risk of Bacterial Pathogen Colonization in InfantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$305,810May 23, 2018April 30, 2023KELLY, MATTHEW SCOTTreporter.nih.gov
Respiratory infections and vaccination behaviors in patients with chronic inflammatory skin diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$305,095July 1, 2019June 30, 2024NOE, MEGAN Hreporter.nih.gov
Type 3 secretion system inhibitors to treat Pseudomonas aeruginosa keratitisNIHNational Eye Institute2022$300,156July 1, 2022June 30, 2023OPPERMAN, TIMOTHY J.reporter.nih.gov
Inhibitors of T3SS translocon assembly to combat multi-drug resistant P. aeruginosaNIHNational Institute of Allergy and Infectious Diseases2021$300,000August 1, 2020May 31, 2024OPPERMAN, TIMOTHY J.reporter.nih.gov
Treatment of Inflammatory Complications of Viral PneumoniaNIHNational Institute of Allergy and Infectious Diseases2022$300,000June 20, 2022August 6, 2023AGRAWAL, ANDYreporter.nih.gov
A comprehensive next generation sequencing diagnostic tool for lung infection among hospitalized patientsNIHNational Institute of Allergy and Infectious Diseases2022$300,000August 11, 2022July 31, 2024FINGERLIN, TASHA E.reporter.nih.gov
Novel antimicrobials in fighting carbapenem-resistant Klebsiella pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2023$300,000December 5, 2022November 30, 2024WU, REENreporter.nih.gov
Self-organizing synthetic human lungs on microchips to fight infection by RSVNIHNational Institute of Allergy and Infectious Diseases2023$300,000May 22, 2023April 30, 2024ETOC, FREDreporter.nih.gov
Bacterial Pneumonia Therapeutic Antibody Safety TrialNIHNational Institute of Allergy and Infectious Diseases2024$297,917July 18, 2024November 30, 2025KAUVAR, LAWRENCE MICHAELreporter.nih.gov
Multivalent Adjuvant Immunization to Prevent Hospital Acquired InfectionsNIHNational Institute of Allergy and Infectious Diseases2021$293,999February 10, 2020June 14, 2022SPELLBERG, BRAD Jreporter.nih.gov
Mechanism of Toxin Mediated Damage to the Lung Epithelium during S. pneumoniae InfectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$293,000April 1, 2024March 31, 2028ADAMS, WALTER ISAIAHreporter.nih.gov
Development of novel protein-based vaccine formulations to prevent pneumococcal colonization and diseaseNIHNational Institute of Allergy and Infectious Diseases2021$283,588September 17, 2020August 31, 2024GONZALEZ-JUARBE, NORBERTOreporter.nih.gov
Lung epithelial cell reprogramming by CD4 T cellsNIHNational Heart, Lung, and Blood Institute2022 to 2023$270,692January 1, 2022March 31, 2023SHENOY, ANUKUL Treporter.nih.gov
Elucidating regulatory control of Acinetobacter baumannii persistence and spreadNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$270,000February 22, 2024January 31, 2027GREEN, ERIN REBECCAreporter.nih.gov
Functional Genetic Analysis of Klebsiella pneumoniae HypervirulenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$268,720July 15, 2021August 31, 2023MIKE, LAURA ANZALDIreporter.nih.gov
Randomized Controlled Trial of Macrolide Therapy for Mycoplasma pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2023$266,860July 1, 2023June 30, 2025AMBROGGIO, LILLIAMreporter.nih.gov
Tobacco Mosaic Virus as a mucosal delivery platform for an intranasal vaccine against Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2025$261,846July 2, 2025June 30, 2027ARNABOLDI, PAUL MICHAELreporter.nih.gov
Development and implementation of a pediatric AI multi-modal digital stethoscope and respiratory surveillance system in South AfricaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$261,763September 4, 2025August 31, 2028MCCOLLUM, ERIC DOUGLASSreporter.nih.gov
Novel Peptide Immunomodulators for Treating SepsisNIHNational Institute of Allergy and Infectious Diseases2023$259,121May 3, 2023April 30, 2026AHMAD, SAIRAreporter.nih.gov
The role of epigenetic regulator UHRF1 in stability of induced regulatory T-cell function during influenza A virus-induced lung injuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$250,698March 1, 2023February 28, 2026JOUDI, ANTHONYreporter.nih.gov
Developing a PIV5-based human metapneumovirus (HMPV) vaccineNIHNational Institute of Allergy and Infectious Diseases2023$249,999May 5, 2023October 31, 2024GINGERICH, MARIA CRISTINAreporter.nih.gov
Defining macrophage defense during Klebsiella pneumoniae bacteremiaNIHNational Institute of Allergy and Infectious Diseases2025$249,000June 11, 2025May 31, 2027HOLMES, CAITLYN LEIGHreporter.nih.gov
Host immunity in the lung is determined by the enhanced utilization of glucose by multi-drug resistant Klebsiella pneumoniaeNIHNational Heart, Lung, and Blood Institute2024 to 2025$246,750January 1, 2024December 31, 2026AHN, DANIELLEreporter.nih.gov
Mechanisms by Which Alcohol-Induced Dysbiosis Impairs Host Defense Against Klebsiella PneumoniaeNIHNational Institute on Alcohol Abuse and Alcoholism2021$246,208September 20, 2019August 31, 2023SAMUELSON, DERRICK Rreporter.nih.gov
Novel mechanistic insights of inflammation and organ injuryNIHNational Heart, Lung, and Blood Institute2025$245,250September 1, 2025May 31, 2029JIN, YANGreporter.nih.gov
Understanding the immunometabolic response to Klebsiella pneumonia infectionNIHNational Heart, Lung, and Blood Institute2022 to 2023$244,302April 1, 2022March 31, 2024WONG FOK LUNG, TANIAreporter.nih.gov
A Point-of-Care Test for Rapid Diagnosis of Valley FeverNIHNational Institute of Allergy and Infectious Diseases2023$243,118July 24, 2023June 30, 2025GRILL, FRANCISCAreporter.nih.gov
Impact of Regulatory T Cells on Host Susceptibility to Pseudomonas Aeruginosa InfectionNIHNational Institute of Allergy and Infectious Diseases2025$239,348November 12, 2024October 31, 2026RIQUELME COLET, SEBASTIAN ALEJANDROreporter.nih.gov
Functions and Mechanisms of Lung Microfold cells during Invasive Pneumococcal DiseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$237,897September 1, 2024July 31, 2026SURVE, MANALEE Vreporter.nih.gov
Identification of new or unrecognized virulence genes in hypervirulent Klebsiella pneumoniae and antivirulence genes in classical K. pneumoniae.NIHNational Institute of Allergy and Infectious Diseases2021$235,744August 19, 2020July 31, 2024RUSSO, THOMAS Areporter.nih.gov
Determining how the giant Streptococcus Pneumoniae IgA1 protease cleaves its host IgA1 substrate and how this interaction can be blockedNIHNational Institute of Allergy and Infectious Diseases2021$233,250December 19, 2019November 30, 2022EISENMESSER, ELAN Zreporter.nih.gov
Lung-innervating nociceptor sensory neurons suppresses Ly6chi monocyte responses to promote pneumonic sepsisNIHNational Institute of Allergy and Infectious Diseases2025$228,000December 1, 2024November 30, 2026BARAL, PANKAJreporter.nih.gov
A vaccine specifically targeting T3SS-negative Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2021$227,250July 12, 2021June 30, 2022PICKING, WENDY L.reporter.nih.gov
Oxidative killing of PneumococcusNIHNational Institute of Allergy and Infectious Diseases2021$226,500March 1, 2020February 28, 2023RADA, BALAZSreporter.nih.gov
Novel Mechanisms of CD4-Independent Immunity Against PneumocystisNIHNational Institute of Allergy and Infectious Diseases2025$226,500July 1, 2025June 30, 2027WRIGHT, TERRY Wreporter.nih.gov
Development of SupraGuard ETT, A Next Generation Composite Endotracheal Tube for the Prevention of Ventilator-Associated PneumoniaNIHNational Heart, Lung, and Blood Institute2021$225,135September 15, 2021July 31, 2023VACHON, DAVID JOHNreporter.nih.gov
Characterization of pneumococcal secretion chaperones required for virulenceNIHNational Institute of Allergy and Infectious Diseases2021$224,638January 1, 2020December 31, 2022CAHOON, LATY ADRIELLAreporter.nih.gov
Capsule protects intracellular pneumococci during vascular endothelial cell translocationNIHNational Institute of Allergy and Infectious Diseases2021$222,750March 1, 2020February 28, 2023ORIHUELA, CARLOS Jreporter.nih.gov
Sex Specific Regulation of B1 B Cell Self-Renewal and Natural Antibody ProductionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$221,204September 1, 2023August 31, 2026WEBSTER, SARAH Ereporter.nih.gov
Genetically engineered macrophages to treat pulmonary infectionsNIHNational Institute of Allergy and Infectious Diseases2021$216,942February 6, 2020January 31, 2024WEST, TIMOTHY EOINreporter.nih.gov
Role of Prp protease in the S. pneumoniae ribosomeNIHNational Institute of Allergy and Infectious Diseases2025$216,068November 8, 2024October 31, 2026DOKLAND, TERJEreporter.nih.gov
Establishing Mechanisms of LOX-1-Dependent Immune Regulation During PneumoniaNIHNational Heart, Lung, and Blood Institute2022 to 2023$212,754August 1, 2022July 16, 2024KORKMAZ, FILIZreporter.nih.gov
Investigating the relationship between antibiotics and nosocomial pneumonia.NIHNational Institute of Allergy and Infectious Diseases2021$211,875January 1, 2020December 31, 2022TORRES, VICTOR J.reporter.nih.gov
Targeting Pneumococcal ColonizationNIHNational Institute of Allergy and Infectious Diseases2021$211,875March 1, 2020February 28, 2023WEISER, JEFFREY NEALreporter.nih.gov
Utilization of the adjuvant effect of CRM197 protein to develop a trivalentprotein-vaccine against Streptococcus pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2021$211,500March 15, 2021February 28, 2022KHAN, NADEEMreporter.nih.gov
Protective lung memory B cell functions and dynamics during respiratory infectionNIHNational Heart, Lung, and Blood Institute2021 to 2024$209,456June 1, 2021May 31, 2025ETESAMI, NEELOUreporter.nih.gov
The Host Genetics of Age-Dependent SusceptibilityNIHNational Institute of Allergy and Infectious Diseases2021$205,083July 1, 2020June 30, 2023MENACHERY, VINEET Dreporter.nih.gov
Age-dependent differences in the immune response to human metapneumovirusNIHNational Heart, Lung, and Blood Institute2022 to 2025$203,115August 15, 2022August 14, 2027PARKS, OLIVIAreporter.nih.gov
Interplay between respiratory syncytial virus and nucleotide biosynthesis pathwaysNIHNational Institute of Allergy and Infectious Diseases2021$199,384February 7, 2020January 31, 2023FEARNS, RACHELreporter.nih.gov
Genetic susceptibility to mucosal infections with aging (Resubmission)NIHNational Institute of Allergy and Infectious Diseases2021$199,375June 1, 2020May 31, 2023BOU GHANEM, ELSAreporter.nih.gov
Extracellular matrix stiffness control of NLRP3 inflammasome activityNIHNational Institute of Allergy and Infectious Diseases2025$197,160July 1, 2025September 26, 2025OKIN, DANIELreporter.nih.gov
Training Program Plan to Improve Intervention Research for Prevention of Childhood Pneumonia in GuatemalaNIHFogarty International Center2022 to 2023$196,969August 15, 2022March 31, 2025CORDON-ROSALES, CELIAreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Northwestern University at ChicagoChicago, IL24$34.7 million0$0
University of Alabama at BirminghamBirmingham, AL18$21.2 million0$0
Vanderbilt University Medical CenterNashville, TN6$19.1 million0$0
University of PennsylvaniaPhiladelphia, PA14$17.6 million0$0
University of Colorado DenverAurora, CO18$17.5 million0$0
Boston University Medical CampusBoston, MA18$16.6 million0$0
Washington UniversitySaint Louis, MO15$15.8 million0$0
Ohio State UniversityColumbus, OH11$15.1 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA25$14.9 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC12$13.3 million0$0
Columbia University Health SciencesNew York, NY11$13 million0$0
University of California, San FranciscoSan Francisco, CA7$12.1 million0$0
Johns Hopkins UniversityBaltimore, MD14$11.6 million0$0
Stanford UniversityStanford, CA6$10.8 million0$0
SUNY at BuffaloAmherst, NY10$10.6 million0$0
University of Michigan at Ann ArborAnn Arbor, MI17$10.2 million0$0
Inhalon Biopharma, Inc.Morrisville, NC5$9.8 million0$0
Brigham and Women's HospitalBoston, MA6$9.5 million0$0
Tulane University of LouisianaNew Orleans, LA7$8.9 million0$0
University of Illinois at ChicagoChicago, IL6$8.2 million0$0
University of South AlabamaMobile, AL10$7.8 million0$0
University of Georgia Research Foundation IncAthens, GA7$7.5 million0$0
University of California, San DiegoLa Jolla, CA6$7.4 million0$0
Lurie Children's Hospital of ChicagoChicago, IL6$7.2 million0$0
University of Maryland Baltimore CountyBaltimore, MD1$7.1 million0$0
Tufts University BostonBoston, MA5$7.1 million0$0
New York University School of MedicineNew York, NY6$7 million0$0
ST. Jude Children's Research HospitalMemphis, TN6$6.8 million0$0
ArietisBoston, MA2$6.6 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA5$6.6 million0$0
Hackensack University Medical CenterHackensack, NJ3$6.4 million0$0
Nubad, LLCGreer, SC2$6.2 million0$0
Vaxnewmo, LLCSaint Louis, MO4$6.2 million0$0
Novobiotic Pharmaceuticals, LLCCambridge, MA1$6.2 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA3$6.1 million0$0
Curza INCSalt Lake City, UT3$5.9 million0$0
Weill Medical Coll of Cornell UnivNew York, NY6$5.9 million0$0
Duke UniversityDurham, NC5$5.7 million0$0
University of Texas Med BR GalvestonGalveston, TX5$5.7 million0$0
Mucommune, LLCMorrisville, NC3$4.9 million0$0
University of Missouri-ColumbiaColumbia, MO6$4.9 million0$0
University of WashingtonSeattle, WA10$4.7 million0$0
University of CincinnatiCincinnati, OH7$4.7 million0$0
University of TX MD Anderson Can CTRHouston, TX2$4.5 million0$0
University of Southern CaliforniaLos Angeles, CA3$4.5 million0$0
Wake Forest University Health SciencesWinston-Salem, NC6$4.5 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH4$4.3 million0$0
University of Texas HLTH Science CenterSan Antonio, TX4$4.2 million0$0
Rockefeller UniversityNew York, NY2$4.2 million0$0
Massachusetts General HospitalBoston, MA6$4.2 million0$0
Emory UniversityAtlanta, GA7$4.1 million0$0
Lundquist Institute for Biomedical Innovation at Harbor-Ucla Medical CenterTorrance, CA2$4.1 million0$0
University of Maryland BaltimoreBaltimore, MD4$4 million0$0
University of FloridaGainesville, FL4$4 million0$0
University of LouisvilleLouisville, KY5$3.7 million0$0
Jackson LaboratoryBar Harbor, ME1$3.5 million0$0
Purdue UniversityWest Lafayette, IN2$3.5 million0$0
Ut Southwestern Medical CenterDallas, TX1$3.4 million0$0
Florida State UniversityTallahassee, FL2$3.4 million0$0
Yale UniversityNew Haven, CT7$3.3 million0$0
University of California-IrvineIrvine, CA3$3.3 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA2$3.3 million0$0
Midwestern UniversityDowners Grove, IL2$3.2 million0$0
Boston Children's HospitalBoston, MA4$3.1 million0$0
Louisiana State UniversityBaton Rouge, LA4$3.1 million0$0
Mayo Clinic RochesterRochester, MN3$3 million0$0
Virginia Commonwealth UniversityRichmond, VA2$3 million0$0
Northeastern UniversityBoston, MA1$3 million0$0
Venatorx Pharmaceuticals, Inc.Malvern, PA1$3 million0$0
Medical University of South CarolinaCharleston, SC2$3 million0$0
Sciogen, LLCSan Jose, CA1$3 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH3$2.9 million0$0
Brown UniversityProvidence, RI1$2.8 million0$0
Albany Medical CollegeAlbany, NY1$2.8 million0$0
Bluewillow Biologics, Inc.Ann Arbor, MI1$2.6 million0$0
Prokaryotics, Inc.Union, NJ3$2.5 million0$0
Western Michigan Univ School of MedicineKalamazoo, MI3$2.5 million0$0
University of IowaIowa City, IA3$2.5 million0$0
University of RochesterRochester, NY2$2.4 million0$0
Dartmouth CollegeHanover, NH1$2.4 million0$0
Baylor College of MedicineHouston, TX2$2.3 million0$0
University of KentuckyLexington, KY3$2.3 million0$0
Eldec Pharmaceuticals, Inc.Durham, NC2$2.2 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA1$2.2 million0$0
University of Nebraska Medical CenterOmaha, NE3$2.2 million0$0
Case Western Reserve UniversityCleveland, OH2$2.1 million0$0
Loyola University ChicagoMaywood, IL2$2 million0$0
Cytoagents, Inc.Pittsburgh, PA1$2 million0$0
Pharmain CorporationBothell, WA1$2 million0$0
Georgia Tech Research CorporationAtlanta, GA2$1.9 million0$0
University of VirginiaCharlottesville, VA3$1.8 million0$0
University of North Dakota Main CampusGrand Forks, ND4$1.8 million0$0
Taxis Pharmaceuticals, Inc.Monmouth Junction, NJ1$1.8 million0$0
Abcombi Biosciences, Inc.Amherst, NY1$1.8 million0$0
University of Maryland, College ParkCollege Park, MD1$1.8 million0$0
University of Mississippi Med CTRJackson, MS3$1.7 million0$0
Carnegie Mellon UniversityPittsburgh, PA2$1.6 million0$0
Rochester General Hospital (ny)Rochester, NY1$1.6 million0$0
Arizona State UniversityScottsdale, AZ1$1.5 million0$0
University of Tennessee Health Sci CTRMemphis, TN2$1.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025247$135,721,1420$0
2024267$135,829,7790$0
2023288$133,661,6960$0
2022268$120,255,8620$0
2021262$119,400,1980$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 6 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 3 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 333 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 333 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 333 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 333 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 333 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 333 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 333 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 333 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 333 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 333 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 333 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 333 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 333 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 333 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 333 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 333 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 333 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.