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Data / Research funding / Physical Injury - Accidents and Adverse Effects

Physical Injury - Accidents and Adverse Effects: 3,284 NIH awards ($4B) to 591 organizations

3,284 NIH awards ($4B) in the NIH spending category Physical Injury - Accidents and Adverse Effects, to 591 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 3,284 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)NIHNational Institute on Drug Abuse2021 to 2022$36,092,167April 17, 2019March 31, 2025WALSH, SHARON L.reporter.nih.gov
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateNIHNational Institute on Drug Abuse2021 to 2023$32,731,263September 15, 2023March 31, 2024EL-BASSEL, NABILAreporter.nih.gov
MassHEAL - Reducing overdose deaths by 40% (2019-2023)NIHNational Institute on Drug Abuse2021 to 2023$29,970,213September 15, 2023March 31, 2024SAMET, JEFFREY H.reporter.nih.gov
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementNIHNational Institute on Drug Abuse2021 to 2023$25,859,414September 15, 2023March 31, 2024FREISTHLER, BRIDGET Jreporter.nih.gov
Mississippi Center for Clinical and Translational ResearchNIHNational Institute of General Medical Sciences2021 to 2025$18,674,548August 18, 2016July 31, 2026GRANGER, JOEY P.reporter.nih.gov
The Wake Forest Nonhuman Primate Radiation Survivor CohortNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,517,826August 1, 2020July 31, 2027CLINE, J. MARKreporter.nih.gov
Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$15,805,224July 1, 2018November 30, 2025BARSAN, WILLIAM Greporter.nih.gov
HEALing Communities Study Health Equity ResearchNIHNational Institute on Drug Abuse2021 to 2023$15,117,207April 1, 2019September 29, 2024OGA, EMMANUEL AJAreporter.nih.gov
1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAHNIHNational Institute on Drug Abuse2021 to 2025$13,649,176September 30, 2015March 31, 2027YURGELUN-TODD, DEBORAH A.reporter.nih.gov
Prevention of Fractures in Patients with Parkinson's DiseaseNIHNational Institute on Aging2022 to 2024$13,269,734September 30, 2018February 28, 2026CUMMINGS, STEVEN RONreporter.nih.gov
Endophenotypes of Persistent Post-Concussive Symptoms in Adolescents: CARE4KidsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$12,522,070September 8, 2021March 31, 2027GIZA, CHRISTOPHER Creporter.nih.gov
Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS studyNIHNational Institute on Aging2021 to 2024$12,122,513September 30, 2020May 31, 2026CAWTHON, PEGGY MANNENreporter.nih.gov
COBRE Center on Opioids and OverdoseNIHNational Institute of General Medical Sciences2021 to 2025$11,768,169September 1, 2018August 31, 2028RICH, JOSIAH Dreporter.nih.gov
Vaccines for fentanyl and its derivatives: A strategy to reduce illicit use and overdoseNIHNational Institute on Drug Abuse2022 to 2024$11,034,562February 1, 2019July 31, 2025PRAVETONI, MARCOreporter.nih.gov
5/21 ABCD-USA Consortium: Research Project Site at UC San DiegoNIHNational Institute on Drug Abuse2021 to 2025$10,821,558September 30, 2015March 31, 2027TAPERT, SUSAN F.reporter.nih.gov
9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGANNIHNational Institute on Drug Abuse2021 to 2025$10,318,458September 30, 2015March 31, 2027HEITZEG, MARY Mreporter.nih.gov
15/21 ABCD-USA Consortium: Research Project Site at LIBRNIHNational Institute on Drug Abuse2021 to 2025$10,302,955April 15, 2020March 31, 2027PAULUS, MARTIN P.reporter.nih.gov
4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIUNIHNational Institute on Drug Abuse2021 to 2025$9,979,334September 30, 2015March 31, 2027GONZALEZ, RAULreporter.nih.gov
PF614-MPAR: clinical development of opioid with oral overdose protectionNIHNational Institute on Drug Abuse2024 to 2025$9,861,616September 1, 2024May 31, 2027KIRKPATRICK, LYNNreporter.nih.gov
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLNIHNational Institute on Drug Abuse2021 to 2025$9,776,479April 15, 2020March 31, 2027MADDEN, PAMELA ANNreporter.nih.gov
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a TrialNIHNational Institute on Aging2021 to 2025$9,481,336February 15, 2021November 30, 2026HANLEY, DANIEL Freporter.nih.gov
2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMBNIHNational Institute on Drug Abuse2021 to 2025$9,449,174September 30, 2015March 31, 2027ERNST, THOMAS Mreporter.nih.gov
University of Michigan Multi-disciplinary Coordinating Center for the Community Firearm Injury Prevention NetworkNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$9,371,829September 15, 2022August 31, 2027CARTER, PATRICK M.reporter.nih.gov
University of New Mexico (UNM) Center for Brain Recovery and RepairNIHNational Institute of General Medical Sciences2021 to 2024$9,061,444September 15, 2015June 30, 2026SHUTTLEWORTH, CLAUDE Wreporter.nih.gov
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,833,081April 15, 2022March 31, 2027GALANOPOULOU, ARISTEA Sreporter.nih.gov
7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALENIHNational Institute on Drug Abuse2021 to 2025$8,739,227September 30, 2015March 31, 2027BASKIN-SOMMERS, ARIELLE RYANreporter.nih.gov
19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVMNIHNational Institute on Drug Abuse2021 to 2025$8,669,646April 15, 2020March 31, 2027GARAVAN, HUGH P.reporter.nih.gov
Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and ManNIHNational Institute on Drug Abuse2024 to 2025$8,480,887September 30, 2019April 30, 2027GRIGSON, PATRICIA SUEreporter.nih.gov
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis PathobiologyNIHNational Institute of General Medical Sciences2021 to 2025$8,479,606May 1, 2021April 30, 2027EFRON, PHILIP Areporter.nih.gov
3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTANIHNational Institute on Drug Abuse2021 to 2025$8,298,588September 30, 2015March 31, 2027LUCIANA, MONICAreporter.nih.gov
6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSUNIHNational Institute on Drug Abuse2021 to 2025$8,270,799September 30, 2015March 31, 2027NAGEL, BONNIE J.reporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2022$8,267,350September 30, 2022September 29, 2025PRAVETONI, MARCOreporter.nih.gov
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderNIHNational Institute on Drug Abuse2021 to 2025$8,148,103April 15, 2020March 31, 2027BANICH, MARIE Treporter.nih.gov
Rutgers University CounterACT Center of ExcellenceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$7,988,704September 15, 2006August 31, 2025LASKIN, JEFFREY Dreporter.nih.gov
Using Implementation Interventions and Peer Recovery Support to Improve Opioid Treatment Outcomes in Community SupervisionNIHNational Institute on Drug Abuse2021 to 2024$7,947,350August 1, 2019April 30, 2025MARTIN, ROSEMARIE Areporter.nih.gov
20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCUNIHNational Institute on Drug Abuse2021 to 2025$7,897,207April 15, 2020March 31, 2027BJORK, JAMES Mreporter.nih.gov
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdoseNIHNational Institute on Drug Abuse2024 to 2025$7,874,666August 15, 2024December 31, 2027FRANCE, CHARLES Preporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,746,716September 15, 2021August 31, 2028BOGNER, JENNIFER Areporter.nih.gov
Reducing Opioid Mortality in Illinois (ROMI)NIHNational Institute on Drug Abuse2021 to 2023$7,594,077July 15, 2019April 30, 2025POLLACK, HAROLD ALEXANDERreporter.nih.gov
Health Systems Node of the NIDA Clinical Trials Network (CTN Project: CTN-141 Hlth Ins Instability)NIHNational Institute on Drug Abuse2021 to 2025$7,514,766March 1, 2025February 29, 2032CAMPBELL, CYNTHIA Ireporter.nih.gov
Endothelial Dysfunction and Restoration in Trauma Induced CoagulopathyNIHNational Heart, Lung, and Blood Institute2023 to 2025$7,179,267September 15, 2023August 31, 2028NEAL, MATTHEW Dreporter.nih.gov
University of Maryland Claude D. Pepper Older Americans Independence Center (OAIC)NIHNational Institute on Aging2021 to 2025$6,970,364September 15, 2006June 30, 2027RYAN, ALICE S.reporter.nih.gov
The Data Science Center for the Study of Surgery and Injury in Africa (D-SINE-Africa)NIHFogarty International Center2021 to 2025$6,927,830September 15, 2021June 30, 2027CHICHOM, ALAIN MEFIREreporter.nih.gov
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug TourismNIHNational Institute on Drug Abuse2021 to 2024$6,868,774April 1, 2020January 31, 2026STRATHDEE, STEFFANIE A.reporter.nih.gov
Resuscitation Strategies for Achieving Thrombo-inflammatory HomeostasisNIHNational Institute of General Medical Sciences2021 to 2023$6,845,824May 20, 2019April 30, 2026COHEN, MITCHELLreporter.nih.gov
18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDANIHNational Institute on Drug Abuse2021 to 2025$6,741,640April 15, 2020March 31, 2027NIXON, SARA JOreporter.nih.gov
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGHNIHNational Institute on Drug Abuse2021 to 2025$6,727,386September 30, 2015March 31, 2027CLARK, DUNCAN B.reporter.nih.gov
Development of cebranopadol, a potent dual MOP/NOP agonist, for the treatment of Opioid Use Disorder (OUD)NIHNational Institute on Drug Abuse2023 to 2024$6,654,182August 15, 2023July 31, 2025GRIECO, JOSEPHreporter.nih.gov
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRINIHNational Institute on Drug Abuse2021 to 2025$6,613,511September 30, 2015March 31, 2027BAKER, FIONA Creporter.nih.gov
17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLANIHNational Institute on Drug Abuse2021 to 2025$6,450,915April 15, 2020March 31, 2027DAPRETTO, MIRELLAreporter.nih.gov
A Life Course Approach to Integrating Trauma and Cognitive Aging: A Cohort of 9/11 RespondersNIHNational Institute on Aging2021 to 2024$6,329,240May 15, 2015April 30, 2026CLOUSTON, SEANreporter.nih.gov
Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project IINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$6,308,426August 15, 2024July 31, 2029ALOSCO, MICHAELreporter.nih.gov
Development of an implantable closed-loop system for delivery of naloxone for the prevention of opioid-related overdose deathsNIHNational Institute on Drug Abuse2021$6,275,050September 30, 2019August 31, 2025GEREAU, ROBERT Wreporter.nih.gov
Neuronal Ion and Volume Shifts After Acute Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,203,269May 1, 2020April 30, 2028STALEY, KEVIN J.reporter.nih.gov
Traumatic Brain Injury and Repetitive Head Impacts: Contributions to AD/ADRD and CTE Neuropathology and Resulting Clinical SyndromesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$6,142,337September 30, 2019July 31, 2025MCKEE, ANN C.reporter.nih.gov
Spinal circuits for mechanical itch and light touchNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,110,688May 1, 2019April 30, 2027GOULDING, MARTYN Dreporter.nih.gov
Restoration of Grasp and Reach in Cervical Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,968,318March 1, 2018August 31, 2025KILGORE, KEVIN L.reporter.nih.gov
11/21 ABCD-USA Consortium: Research Project Site at UWMNIHNational Institute on Drug Abuse2021 to 2025$5,941,105July 15, 2017March 31, 2027LISDAHL, KRISTA MAURINEreporter.nih.gov
URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related DementiasNIHNational Institute on Aging2021 to 2024$5,941,036September 1, 2019May 31, 2026NELSON, LONNIE A.reporter.nih.gov
Penn PET Addiction Center of Excellence (PACE)NIHNational Institute on Drug Abuse2021 to 2023$5,914,143August 15, 2019June 30, 2025MACH, ROBERT Hreporter.nih.gov
13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSCNIHNational Institute on Drug Abuse2021 to 2025$5,745,020July 1, 2017March 31, 2027SQUEGLIA, LINDSAYreporter.nih.gov
Intracranial multimodal physiological monitoring in acute brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$5,648,369August 15, 2022July 31, 2025SPENCER, DENNIS Dreporter.nih.gov
CCC for NHLBI Prevention and Early Treatment of Acute Lung Injury PETAL NetworkNIHNational Heart, Lung, and Blood Institute2021$5,617,232June 17, 2014October 31, 2023THOMPSON, BOYD TAYLORreporter.nih.gov
Meth-OD: A PHASE 2A STUDY OF IXT-M200 IN METHAMPHETAMINE OVERDOSE PATIENTSNIHNational Institute on Drug Abuse2021 to 2022$5,613,312September 30, 2020June 30, 2024STEVENS, MISTY WARDreporter.nih.gov
Overcoming Neurogenic “Meta-Inflammation” to Promote Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,600,627May 1, 2019April 30, 2027POPOVICH, PHILLIP Greporter.nih.gov
PF614 MPAR Abuse Deterrent opioid prodrug with overdose protection: Pre-Clinical Development and Phase 1 Clinical TrialNIHNational Institute on Drug Abuse2021 to 2022$5,585,570September 15, 2018December 31, 2023KIRKPATRICK, LYNNreporter.nih.gov
IMPACCT: Infrastructure for Musculoskeletal Pediatric Acute Care Clinical TrialsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$5,541,590September 1, 2021February 28, 2027JANICKI, JOSEPH Areporter.nih.gov
JCOIN data curation and archivingNIHNational Institute on Drug Abuse2024 to 2025$5,521,141June 15, 2019May 31, 2029SCHNEIDER, JOHNreporter.nih.gov
16/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UNIVERSITY OF ROCHESTERNIHNational Institute on Drug Abuse2021 to 2025$5,419,981April 15, 2020March 31, 2027FOXE, JOHN Jreporter.nih.gov
GATHER: Growing a Tribal Healing Effort through ResearchNIHNational Institute on Drug Abuse2024 to 2025$5,340,103August 1, 2024July 31, 2026PARKER, MYRA ELIZABETHreporter.nih.gov
Kentucky Women's Justice Community Opioid Innovation Network (WJCOIN)NIHNational Institute on Drug Abuse2021 to 2023$5,280,405July 15, 2019April 30, 2026STATON, MICHELEreporter.nih.gov
Measuring Whole and Tissue Level Bone Strength in menNIHNational Institute on Aging2021 to 2025$5,213,084January 1, 2021May 31, 2027BURKS, PETERreporter.nih.gov
Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodologyNIHNational Institute of Mental Health2024 to 2025$5,154,254August 9, 2024May 31, 2028WILCOX, HOLLY Creporter.nih.gov
Fentalog II: Medical Consequences of Novel Fentanyl Analog Overdose Using the Toxicology Investigators Consortium (TOXIC)NIHNational Institute on Drug Abuse2021 to 2025$5,080,519April 1, 2020March 31, 2030MANINI, ALEX FRANCISreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$5,043,999September 15, 2021August 31, 2023BOGNER, JENNIFER Areporter.nih.gov
Clinical & biological signatures of post-traumatic neurodegeneration: Leveraging the TBI Model Systems of Care to accelerate in vivo diagnosis of the late effects of TBI (LETBI)NIHNational Institute of Neurological Disorders and Stroke2022$5,005,696September 1, 2022August 31, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
HEAL Initiative: Research to Foster an Opioid Use Disorder Treatment System Patients Can Count OnNIHNational Institute on Drug Abuse2023 to 2025$4,935,947September 30, 2023August 31, 2028MARK, TAMI Lreporter.nih.gov
Rapid Actionable Data for Opioid Response in Kentucky (RADOR-KY)NIHNational Institute on Drug Abuse2022 to 2025$4,881,729September 30, 2022August 31, 2027SLAVOVA, SVETLA STEFANOVAreporter.nih.gov
Combining Testosterone Therapy and Exercise to Improve Function Post Hip FractureNIHNational Institute on Aging2022 to 2023$4,873,117September 15, 2017May 31, 2025BINDER, ELLEN Freporter.nih.gov
1/2 Trauma Resuscitation with Group O Whole Blood Or Products (TROOP) TrialNIHNational Heart, Lung, and Blood Institute2023 to 2025$4,870,584August 5, 2022July 31, 2027JANSEN, JAN Oreporter.nih.gov
Delineating mechanisms of skeletal fragility in older adults with Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,798,865February 1, 2021January 31, 2027YU, ELAINE WEI-YINreporter.nih.gov
Spinal Cord Stimulation to Improve Motor Function in People with Post-Stroke HemiplegiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$4,671,700September 8, 2022August 31, 2025CAPOGROSSO, MARCOreporter.nih.gov
Hyperbaric Oxygen Brain Injury Treatment (HOBIT) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,664,374September 30, 2017June 30, 2029ROCKSWOLD, GAYLAN Lreporter.nih.gov
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid AnalgesicsNIHNational Institute on Drug Abuse2024 to 2025$4,623,799September 30, 2019December 31, 2026CORTES-PUCH, IRENEreporter.nih.gov
Brain fluid clearance and misfolded protein dynamics following traumatic brain injuryNIHNational Institute on Aging2023 to 2025$4,618,282September 30, 2023June 30, 2029BUTLER, TRACY A.reporter.nih.gov
Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk FactorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,613,790December 15, 2015November 30, 2023STERN, ROBERT Areporter.nih.gov
Sensory Motor Transformations in Human CortexNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,572,652August 15, 2021July 31, 2026ANDERSEN, RICHARD Areporter.nih.gov
An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCIDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,539,313September 22, 2023August 31, 2028VAN DER KOUWE, ANDRE JAN WILLEMreporter.nih.gov
A Pragmatic Crossover Trial to Test the Effectiveness of a Novel Lighting System to Reduce Nighttime Falls in Persons with Alzheimer’s Disease and Related DementiasNIHNational Institute on Aging2022 to 2025$4,499,469July 1, 2022June 30, 2028ZIMMERMAN, SHERYLreporter.nih.gov
National Drug Early Warning System Coordinating Center (NDEWS)NIHNational Institute on Drug Abuse2021 to 2025$4,490,739April 1, 2020February 28, 2030COTTLER, LINDA B.reporter.nih.gov
Optimizing ultraflexible electrodes and integrated electronics for high-resolution, large-scale intraspinal recording and modulationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$4,423,695August 15, 2023July 31, 2027XIE, CHONGreporter.nih.gov
Impact of a novel HIV peer navigationand overdose prevention intervention on engagement in the HIV prevention and treatment cascade.NIHNational Institute on Drug Abuse2021 to 2025$4,391,293September 1, 2021June 30, 2027SHERMAN, SUSAN G.reporter.nih.gov
A comparative evaluation of overdose prevention programs in New York City and Rhode IslandNIHNational Institute on Drug Abuse2023 to 2025$4,373,618May 1, 2023February 28, 2027CERDA, MAGDALENAreporter.nih.gov
Methocinnamox (MCAM): A novel opioid receptor antagonistNIHNational Institute on Drug Abuse2023$4,373,045July 1, 2023June 30, 2024FRANCE, CHARLES Preporter.nih.gov
WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use DisorderNIHNational Institute on Drug Abuse2022 to 2025$4,339,941September 30, 2022August 31, 2028ADAMS, MEREDITH C. B.reporter.nih.gov
Tools for Common Data Element Adoption in the Pan-Neurotrauma Data Commons (PANORAUMA)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,311,013September 1, 2021January 31, 2026FERGUSON, ADAM Rreporter.nih.gov
Biased Mu-Opioid Receptor Analgesics to Prevent Overdose and Opioid Use DisordersNIHNational Institute on Drug Abuse2021 to 2023$4,306,927September 15, 2018August 31, 2023KUO, LAWRENCE Creporter.nih.gov
The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)NIHNational Institute of Neurological Disorders and Stroke2021$4,283,451May 8, 2020November 30, 2022TOGA, ARTHUR Wreporter.nih.gov
Consequences of Exposure to Repetitive Head Impacts Across the LifespanNIHNational Institute of Neurological Disorders and Stroke2025$4,269,339June 1, 2025May 31, 2027MCKEE, ANN C.reporter.nih.gov
A Proposal to Establish the Mississippi Violence Injury Prevention (VIP) ProgramNIHNational Institute on Minority Health and Health Disparities2024$4,268,296September 15, 2022June 30, 2027ZHANG, LEIreporter.nih.gov
DEVELOPMENT OF ANTICERAMIDE TREATMENT AS A NOVEL MEDICAL COUNTERMEASURE FOR ACUTE EFFECTS OF RADIATION EXPOSURENIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,223,612July 1, 2023September 30, 2025DIMMLER III, CHARLESreporter.nih.gov
Neuroimaging and clinical Endpoints With High-dimensional analysis Of Pathological Endophenotypes in TBI (NEW-HOPE-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$4,213,033August 15, 2024July 31, 2029KEENE, CHRISTOPHER DIRKreporter.nih.gov
Pooling International Cohort Studies of Long-Term Bisphosphonate Use and Atypical Femur FracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$4,209,170September 19, 2022August 31, 2027BAUER, DOUGLAS Creporter.nih.gov
Preclinical Development of a Novel Therapeutic to Rejuvenate Aging Muscle Stem Cells and Enhance Muscle Strength and Function Post Hip FractureNIHNational Institute on Aging2021 to 2024$4,202,826September 30, 2021August 31, 2025NEELAKANTAN, HARSHINIreporter.nih.gov
Genome-Wide Discovery and Translational Research for Neural RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,147,990December 1, 2016November 30, 2025STRITTMATTER, STEPHEN Mreporter.nih.gov
Novel Therapeutics for Opioid Use Disorder in the Acute Overdose and Maintenance SettingsNIHNational Institute on Drug Abuse2022 to 2023$4,143,992September 30, 2019August 31, 2025GEHLERT, DONALD Rreporter.nih.gov
Using SMART Design to Identify an Effective and Cost-Beneficial Approach to Preventing OUD in Justice-Involved YouthNIHNational Institute on Drug Abuse2021 to 2023$4,080,444September 30, 2019August 31, 2024AHRENS, KYM Rreporter.nih.gov
A Biomimetic Approach Towards a Dexterous NeuroprosthesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$4,074,988September 30, 2018June 30, 2025BONINGER, MICHAEL L.reporter.nih.gov
Changing the Narrative on Firearms Violence: A Community Collaborative InterventionNIHNational Institute on Minority Health and Health Disparities2024$4,037,500September 15, 2022June 30, 2026EDBERG, MARKreporter.nih.gov
1/7 Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2025$4,004,222July 1, 2021June 30, 2028GIRGIS, RAGY RAMSISreporter.nih.gov
Transdisciplinary Research Accelerating Neuropathology Studies and Facilitating Open Research Methods in TBI (TRANSFORM-TBI)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,951,871June 1, 2024April 30, 2029SMITH, DOUGLAS HAMILTONreporter.nih.gov
Development of novel therapeutics for opioid dependenceNIHNational Institute on Drug Abuse2021 to 2022$3,944,970September 30, 2018August 31, 2024KENNY, PAUL J.reporter.nih.gov
Researching Effective Strategies to Prevent Opioid Death (RESPOND)NIHNational Institute on Drug Abuse2021 to 2025$3,943,189June 1, 2018July 31, 2028LINAS, BENJAMIN P.reporter.nih.gov
Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,917,121February 1, 2021January 31, 2027ALOSCO, MICHAELreporter.nih.gov
Characterizing Wnt Signaling Pathways in Axon GuidanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,896,283June 15, 2023May 31, 2026ZOU, YIMINreporter.nih.gov
Multicellular Mechanisms Driving Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,884,176May 17, 2021April 30, 2029CAVALLI, VALERIAreporter.nih.gov
Minimally Invasive Cerebral Blood Flow and Oxygenation Monitoring for Intracranial HypertensionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,861,972September 20, 2022November 30, 2026FLOYD, THOMAS FREDERICKreporter.nih.gov
Defining the Role of Post-TBI Sleep Disruption in the Development of CTE and Alzheimer's Disease-Related NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2022$3,859,922September 20, 2022August 31, 2025PESKIND, ELAINE R.reporter.nih.gov
Towards healthy aging: Quantifying vestibular contributors to age-related changes in balance and fall riskNIHNational Institute on Aging2021 to 2025$3,844,409September 30, 2021May 31, 2027MERFELD, DANIEL Mreporter.nih.gov
Leveraging Artificial Intelligence Solutions to Develop Digital Biomarkers for Precision Trauma ResuscitationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,841,542December 1, 2019November 30, 2025CALLCUT, RACHAEL Areporter.nih.gov
An automated portable system for detecting and treating opioid induced respiratory depressionNIHNational Institute on Drug Abuse2022 to 2024$3,830,637April 1, 2022February 28, 2026MACKIE, KENNETHreporter.nih.gov
Utility of Esophageal Cooling Therapy for the Prevention of Thermal Injury During Atrial FibrillationNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,800,000September 15, 2021July 31, 2025KULSTAD, ERIK BENJAMINreporter.nih.gov
Language Processing in Context Following Traumatic Brain InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,792,881December 11, 2019May 31, 2030DUFF, MELISSA Creporter.nih.gov
Neural sensitivity to social evaluation and daily online and in-person social experience with peers: Predicting fluctuations in suicidality, self-harm, and depressive symptoms in adolescent girlsNIHNational Institute of Mental Health2021 to 2025$3,781,212August 1, 2021May 31, 2027SILK, JENNIFER Sreporter.nih.gov
Spatio-temporal Methods for Surveillance of the Opioid SyndemicNIHNational Institute on Drug Abuse2021 to 2025$3,748,657September 1, 2025August 31, 2029KLINE, DAVID Mreporter.nih.gov
Epidural spinal cord stimulation and respiratory motor function after injuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,733,906May 1, 2021February 28, 2027OVECHKIN, ALEXANDER VLADIMIROVICHreporter.nih.gov
Clinical Trial to Demonstrate Impact of an AI-enabled 3D Ultrasound-based Guidance System in Reducing Arteriovenous Fistula Cannulation Injury and Improving Patient Quality of LifeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,709,998September 15, 2021July 31, 2026KANG, XINreporter.nih.gov
Development and Validation of a Novel and HIV-Relevant Prediction Model for FractureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,707,719April 1, 2021March 31, 2027HSIEH, EVELYNreporter.nih.gov
Stimulation of novel spinal respiratory circuit to restore breathing in ventilator-dependent patients with SCI.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,702,825August 1, 2021December 31, 2027LU, DANIELreporter.nih.gov
Targeting Cell-Type Specific Disease Phenotypes to Promote CNS RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,654,519August 1, 2023April 30, 2028LEE, JAE Kreporter.nih.gov
Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)NIHNational Institute on Aging2021 to 2023$3,567,627March 15, 2019November 30, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Development and validation of a porcine model of spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$3,560,956September 21, 2023August 31, 2026FLOYD, CANDACE L.reporter.nih.gov
Precision Therapy for Neonatal Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,537,721December 1, 2016November 30, 2024FERRIERO, DONNA M.reporter.nih.gov
Synthetics in Combination (SYNC)NIHNational Institute on Drug Abuse2021 to 2025$3,536,582September 30, 2021June 30, 2026CICCARONE, DANIEL Hreporter.nih.gov
Understanding Bystanders for Self-Directed Violence Prevention: A Prospective National Study Highlighting Marginalized Youth and Young AdultsNIHNational Institute of Mental Health2021 to 2025$3,536,497September 13, 2021June 30, 2027MITCHELL LEMA, KIMBERLY Jreporter.nih.gov
Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,525,423August 23, 2004December 31, 2028KEENAN, HEATHER T.reporter.nih.gov
Support via Online Social Networks to Promote safe Infant Care Practices Toward Reducing Racial Disparities in Infant Mortality (SUPERSONIC)NIHNational Institute on Minority Health and Health Disparities2021 to 2025$3,498,848July 10, 2014January 31, 2027MOON, RACHEL Yreporter.nih.gov
Biomechanical and Biological Predictors of Cartilage Health Following Meniscus InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,493,420April 5, 2021March 31, 2026MCNULTY, AMY Lreporter.nih.gov
Locomotor function following transcutaneous electrical spinal cord stimulation in individuals with hemiplegic strokeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,493,081August 12, 2021July 31, 2027JAYARAMAN, ARUNreporter.nih.gov
Determinants and Outcomes of Age-related Muscle LossNIHNational Institute on Aging2021 to 2025$3,472,889September 30, 2021June 30, 2027KIEL, DOUGLAS P.reporter.nih.gov
Visuomotor Prosthetic for ParalysisNIHNational Eye Institute2021 to 2025$3,468,480May 1, 2021March 31, 2026ANDERSEN, RICHARD Areporter.nih.gov
Enhancing Respiratory Motor Function after Spinal Cord InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,467,620January 1, 2019March 31, 2027SIECK, GARY C.reporter.nih.gov
UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and SustainabilityNIHNational Institute on Drug Abuse2023 to 2025$3,424,229September 30, 2023July 31, 2028LANKENAU, STEPHEN Ereporter.nih.gov
SMART Stepped Care Management for Low Back Pain in Military Health SystemNIHNational Center for Complementary & Integrative Health2021 to 2022$3,420,219September 20, 2017August 31, 2025FRITZ, JULIE Mreporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2025$3,410,308September 30, 2022July 31, 2028PRAVETONI, MARCOreporter.nih.gov
Mechanisms of Immune Dysfunction after Trauma and Surgical SepsisNIHNational Institute of General Medical Sciences2021 to 2025$3,405,189June 1, 2018May 31, 2028BILLIAR, TIMOTHY Rreporter.nih.gov
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL ReconstructionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,403,884August 1, 2018July 31, 2025SPINDLER, KURT PAULreporter.nih.gov
Commercialization of an Improved Treatment of Extremity Fractures Using a Regenerative Bone Adhesive to Accelerate Bone Healing in Aging PatientsNIHNational Institute on Aging2023 to 2025$3,400,899September 30, 2023August 31, 2026HESS, BRIANreporter.nih.gov
Blood-based AD biomarkers profile in CAPCOG-TBI studyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,393,269September 1, 2023May 31, 2028DING, KANreporter.nih.gov
Evaluating the impact of fentanyl test strip use among rural and urban populationsNIHNational Institute on Drug Abuse2021 to 2025$3,392,442July 1, 2021April 30, 2027MICHAELS, NICHOLE Lreporter.nih.gov
Brain Injury Outpatient Education and Care NavigationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,389,312August 15, 2021April 30, 2027RIVARA, FREDERICK P.reporter.nih.gov
Defining short RNA therapeutics that combat TDP-43 proteinopathy connected to AD and ADRDs.NIHNational Institute on Aging2025$3,360,074September 15, 2025August 31, 2029SHORTER, JAMESreporter.nih.gov
Promoting remote and secondary risk prevention services in rural settingsNIHNational Institute on Drug Abuse2022 to 2025$3,349,340September 30, 2022July 31, 2027PHO, MAI TUYETreporter.nih.gov
Fatal Overdose Review Teams - Research to Enhance Surveillance Systems (FORTRESS)NIHNational Institute on Drug Abuse2024$3,330,528September 30, 2022August 31, 2027AALSMA, MATTHEWreporter.nih.gov
The Primate Corticospinal Connectome and TranscriptomeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,321,910September 15, 2017May 31, 2026TUSZYNSKI, MARK H.reporter.nih.gov
Personalized Integrated Alcohol and Sexual Assault Prevention among College StudentsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,321,878September 25, 2021May 31, 2027GILMORE, AMANDA KATHERINEreporter.nih.gov
Evaluating naloxone-on-release from incarceration as community overdose preventionNIHNational Institute on Drug Abuse2022 to 2025$3,318,365June 15, 2022April 30, 2027DAVIDSON, PETER JOHNreporter.nih.gov
Novel peptide-impregnated hydrogel as a wound healing deviceNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,317,905April 1, 2016August 31, 2025ZHENG, ZHONGreporter.nih.gov
Contributions of astrocyte RelA signaling in aging-related neurodegenerative sequelae following TBINIHNational Institute on Aging2021 to 2025$3,313,377January 15, 2021December 31, 2026MORGANTI, JOSHreporter.nih.gov
Spinal Cord Associative PlasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,299,466September 10, 2021June 30, 2026CARMEL, JASON BRANTreporter.nih.gov
A geospatial analysis of hotspots and targeted injection settings pilot intervention for HIV prevention among people who inject drugs in Baltimore, MarylandNIHNational Institute on Drug Abuse2021 to 2025$3,292,995July 1, 2020May 31, 2027LATKIN, CARL Areporter.nih.gov
Primary Palliative Care for Emergency MedicineNIHNational Center for Complementary & Integrative Health2021 to 2022$3,292,922May 15, 2018June 30, 2025GOLDFELD, KEITHreporter.nih.gov
Understanding Social Support Network Characteristics, Alcohol Misuse, and Posttraumatic Stress among Survivors of Sexual Assault in the First-year Post-assaultNIHNational Institute on Alcohol Abuse and Alcoholism2025$3,291,402September 11, 2025August 31, 2029JAFFE, ANNA E.reporter.nih.gov
Harmonizing Hospital-Based Violence Intervention Programs with a Novel Medical-Legal Partnership – the HVIP-MLP ModelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$3,280,000September 15, 2022August 31, 2027ZAKRISON, TANYA Lreporter.nih.gov
Recovering Together: Building resiliency in dyads of patients with an acute brain injury admitted to the Neuroscience Intensive Care Unit and their informal caregiversNIHNational Institute of Nursing Research2021 to 2025$3,279,137August 6, 2021May 31, 2027VRANCEANU, ANA-MARIAreporter.nih.gov
MITIGATION OF MULTI-ORGAN DELAYED EFFECTS OF ACUTE RADIATION EXPOSURE (DEARE) WITH ACE-INHIBITOR LISINOPRILNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,275,826July 1, 2023June 30, 2026LANDRUM, JILLreporter.nih.gov
Reducing Alcohol Involved Sexual violence in higher Education (RAISE)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,275,604August 20, 2014May 31, 2027KAZMERSKI, TRACI Mreporter.nih.gov
Alcohol's Effects on Affective, Cognitive, and Behavioral Responses in a Virtual Reality Dating SimulationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,272,691September 22, 2021August 31, 2027ABBEY, ANTONIAreporter.nih.gov
Biomarkers of Tissue Tolerance and Behavior in a Rat ModelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,262,661July 1, 2009May 31, 2026BARBE, MARY Freporter.nih.gov
Novel Molecular Biomarkers of Bone MicroarchitectureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,202,138September 30, 1991March 31, 2027KIEL, DOUGLAS P.reporter.nih.gov
Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRINIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$3,194,922July 16, 2019June 30, 2025LI, XIAOJUANreporter.nih.gov
Development of a first-in-class nonmuscle myosin II inhibitor to prevent substance use disorder relapseNIHNational Institute on Drug Abuse2021 to 2023$3,182,913September 30, 2021August 31, 2024YOUNG, ERICA Jreporter.nih.gov
An integrated exercise and bladder training intervention to reduce falls in older women with urinary incontinenceNIHNational Institute on Aging2021 to 2025$3,172,146September 30, 2021August 31, 2026ANDY, UDUAK UMOHreporter.nih.gov
Intimate Partner Violence and HIV Prevention among Sexual Minority MenNIHNational Institute of Mental Health2021 to 2025$3,158,226May 1, 2021February 28, 2027STORHOLM, ERIK D.reporter.nih.gov
A longitudinal study of traumatic brain injury in a high-risk populationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,150,729August 4, 2022May 31, 2027KIEHL, KENT Areporter.nih.gov
Multiscale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor controlNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,147,181September 16, 2016March 31, 2027TING, LENA Hreporter.nih.gov
Optimization of Novel Molecular Target-based Drugs for Arsenical Skin InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,140,852September 10, 2020August 31, 2025ATHAR, MOHAMMADreporter.nih.gov
Longitudinal MRI Investigation of Traumatic Microvascular InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,116,729February 15, 2022January 31, 2027WARE, JEFFREY Breporter.nih.gov
Vascular Mechanisms Underlying Skeletal Fragility in Older AdultsNIHNational Institute on Aging2021 to 2025$3,114,001December 15, 2020November 30, 2026SAMELSON, ELIZABETH Jreporter.nih.gov
Modeling the role of age at traumatic brain injury in the development of Alzheimer's Disease and related dementiasNIHNational Institute of Neurological Disorders and Stroke2024$3,109,079August 1, 2024July 31, 2027OBENAUS, ANDREreporter.nih.gov
Exosome biology in Alzheimer's disease and concussionNIHNational Institute on Aging2021 to 2025$3,108,983August 15, 2021April 30, 2027GRANHOLM-BENTLEY, ANN-CHARLOTTE ESTHERreporter.nih.gov
Implementation of Overdose Prevention Practices in Permanent Supportive HousingNIHNational Institute on Drug Abuse2022 to 2025$3,104,337May 1, 2022March 31, 2027DORAN, KELLYreporter.nih.gov
Developing Gyrencephalic Models of TBI-Induced ADRD NeuropathologyNIHNational Institute of Neurological Disorders and Stroke2024$3,102,638August 15, 2024July 31, 2027JOHNSON, VICTORIA ELEANORreporter.nih.gov
A comparative effectiveness trial of sublingual versus extended-release buprenorphine with individuals leaving a carceral settingNIHNational Institute on Drug Abuse2023 to 2025$3,097,234September 30, 2023June 30, 2029GORDON, MICHAEL SCOTTreporter.nih.gov
Multimodal Analysis of Gestational Health and Placental Injury in Opioid-Affected PregnanciesNIHNational Institute on Drug Abuse2023$3,092,159August 15, 2023July 30, 2026OUYANG, YINGSHIreporter.nih.gov
A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care SystemsNIHNational Institute of Mental Health2022 to 2025$3,083,245September 1, 2022June 30, 2027ZATZICK, DOUGLAS Freporter.nih.gov
Biophysical detection of skin changes to cue pressure injury prevention in nursing homesNIHNational Institute of Nursing Research2022 to 2025$3,082,374September 19, 2022June 30, 2027BATES-JENSEN, BARBARA M.reporter.nih.gov
Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,082,121March 15, 2020February 28, 2027DIAZ-ARRASTIA, RAMONreporter.nih.gov
Acid-Base Status as a Novel Risk Factor for FracturesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,080,006June 1, 2019February 28, 2026PAIK, JULIEreporter.nih.gov
Spinal Reflex Conditioning System for Enhancing Motor Function Recovery After Incomplete Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,077,317September 30, 2020December 31, 2026CLEMENTS, ISAAC PERRYreporter.nih.gov
Intensive Lifestyle Intervention, Metabolomics, and Risk of Frailty Fracture in Overweight or Obese Patients with Type 2 DiabetesNIHNational Institute on Aging2021 to 2025$3,069,231September 30, 2021May 31, 2027ZHAO, QIreporter.nih.gov
The glymphatic system at the crossroad of integrative health approaches inchronic painNIHNational Center for Complementary & Integrative Health2021 to 2025$3,067,927August 1, 2021May 31, 2026NEDERGAARD, MAIKENreporter.nih.gov
A Randomized Clinical Trial of Scenario Planning for Older Adults with Serious InjuryNIHNational Institute on Aging2022 to 2025$3,063,146September 30, 2022June 30, 2027SCHWARZE, MARGARETreporter.nih.gov
Detection of Elder mistreatment Through Emergency Care Technicians - Revised for Primary Care (DETECT-RPC)NIHNational Institute on Aging2024 to 2025$3,056,003September 15, 2022August 31, 2028BURNETT, JASON LEEreporter.nih.gov
First Aid Medicine to Treat Vesicant Induced Corneal InjuryNIHNational Eye Institute2022 to 2025$3,055,554September 30, 2022August 31, 2027CHANDLER, HEATHERreporter.nih.gov
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathiesNIHNational Institute on Aging2022 to 2025$3,053,656June 1, 2022February 28, 2027LIAO, DEZHIreporter.nih.gov
The short and long-term dynamics of opioid/stimulant use: Mixed methods to inform overdose prevention and treatment related to polysubstance useNIHNational Institute on Drug Abuse2022 to 2025$3,051,259September 30, 2022July 31, 2027GENBERG, BECKY LYNNreporter.nih.gov
Maladaptive Plasticity in Spinal Cord Injury: Cellular MechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,505July 15, 2021June 30, 2026FERGUSON, ADAM Rreporter.nih.gov
Macrophage Depletion Therapy for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,042,324March 15, 2021November 30, 2025GENSEL, JOHN Creporter.nih.gov
TRUE HAVEN: TRUsted rEsidents and Housing Assistance to decrease Violence Exposure in New HavenNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,041,100July 22, 2022March 31, 2027WANG, EMILY AI-HUAreporter.nih.gov
Characterization of spinal circuits underlying motor synergy functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,029,088September 1, 2021August 31, 2026PFAFF, SAMUEL L.reporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
Implementing and evaluating the impact of novel mobile harm reduction services on overdose among women who use drugs: The SHOUT study.NIHNational Institute on Drug Abuse2022 to 2025$3,024,580September 30, 2022July 31, 2027SHERMAN, SUSAN G.reporter.nih.gov
Strategy to Potentiate Rehabilitation after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,022,533December 1, 2020November 30, 2026HARRIS, NEILreporter.nih.gov
Pediatric Severe Traumatic Brain Injury in Latin America – A Randomized Trial Comparing Two Management ProtocolsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,020,262August 1, 2021July 31, 2027CHESNUT, RANDALL Mreporter.nih.gov
A unified protocol to address sexual minority women's minority stress, mental health and hazardous drinkingNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$3,019,278September 12, 2022August 31, 2027PACHANKIS, JOHN EDWARDreporter.nih.gov
Addressing Trauma from Interpersonal Violence through a Web-based Peer Navigation-Social Support Intervention to Improve ART Adherence among WomenNIHNational Institute of Mental Health2021 to 2025$3,010,028July 1, 2021November 30, 2026STOCKMAN, JAMILA KINSHASAreporter.nih.gov
Mechanisms of repeated opioid use dependent remodeling in respiratory controlNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,007,583August 5, 2022May 31, 2026GARCIA, ALFREDO Jreporter.nih.gov
Non-Clinical Pharmacology of CX-01NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,007,043June 1, 2014January 31, 2027VID, GALINAreporter.nih.gov
Mechanisms of Radiation-Induced Innate Immune Dysfunction and Its CountermeasuresNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,005,089July 21, 2022May 31, 2027WANG, PINGreporter.nih.gov
Development of a Novel Chemokine Receptor Antagonist Peptide as a Non-Opioid Treatment for Relief of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021$2,999,505September 15, 2021August 31, 2023RUFF, MICHAEL Rreporter.nih.gov
A Novel Reversal Agent for Treatment of Overdose from the Combination of Fentanyl and XylazineNIHNational Institute on Drug Abuse2024 to 2025$2,999,483August 1, 2024July 31, 2026LI, XINHUAreporter.nih.gov
Counteracting Structural Barriers to Increase Access to Medications for Opioid Use Disorder (MOUD) Among Unhoused MontanansNIHOffice of the Director, National Institutes of Health2023 to 2025$2,999,246September 22, 2023September 21, 2028RAMOS, REBECCAreporter.nih.gov
Improving MOUD Access, Opioid-Related Outcomes and Equity Among Medicare Beneficiaries with DisabilityNIHNational Institute on Drug Abuse2022 to 2025$2,994,575September 1, 2022June 30, 2027CRYSTAL, STEPHENreporter.nih.gov
Development of a novel, regenerative therapy to reverse synapse loss in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$2,994,510June 1, 2023May 31, 2025VANDERKLISH, PETER Wreporter.nih.gov
Impact of peripheral nerves on mesenchymal cell fate in extremity traumaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,991,689August 1, 2017April 30, 2026LEVI, BENJAMINreporter.nih.gov
Optimizing a technology-based body and mind intervention to prevent falls and reduce health disparities in low-income populationsNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,988,012September 26, 2022June 30, 2027THIAMWONG, LADDAreporter.nih.gov
Modulation of chemokine signaling to mitigate radiation induced inflammationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,977,133July 21, 2022May 31, 2027SAHA, SUBHRAJITreporter.nih.gov
Machine-Learning Prediction and Reducing Overdoses with EHR Nudges (mPROVEN)NIHNational Institute on Drug Abuse2022 to 2025$2,975,448September 1, 2017April 30, 2027GELLAD, WALID F.reporter.nih.gov
Comprehensive Phenotyping of Specific Populations of Spinal Neurons Processing Cutaneous Information Before and After InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,973,851September 16, 2016August 31, 2026KOERBER, H RICHARDreporter.nih.gov
Analytical characterization and validation of blood-biomarkers for monitoring TBI evolutionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,965,270August 10, 2024July 31, 2028PUCCIO, AVA M.reporter.nih.gov
Comprehensive Outcome Assessment after Severe Acute Brain Injury: Advanced Symptoms and End-of-Life Care NeedsNIHNational Institute of Nursing Research2021 to 2025$2,965,004May 12, 2021March 31, 2027CREUTZFELDT, CLAIRE JOHANNAreporter.nih.gov
Turbo Eye Drops to Treat Ocular Toxicity and Blindness from Sulfur MustardNIHNational Eye Institute2021 to 2024$2,948,924August 1, 2020July 31, 2025MOHAN, RAJIV RAVINDRAreporter.nih.gov
Trauma and Neurobiological Threat Reactivity as Risk Factors for Alcohol Abuse in YouthNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,948,602March 10, 2021February 28, 2027GORKA, STEPHANIEreporter.nih.gov
NX90: A Treatment for Overdose Caused by High Potency OpioidsNIHNational Institute on Drug Abuse2024 to 2025$2,946,808September 30, 2024August 31, 2026VORONKOV, MICHAEL V.reporter.nih.gov
Targeted Biomarker Panels and Pre-processing Device for the Rapid Assessment of Radiation Injury in Easily Accessible BiofluidsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,938,166July 27, 2021April 30, 2027LAIAKIS, EVAGELIA CHRISTOSreporter.nih.gov
Housing Policies and their Impact on Engagement in Substance Use Treatment and Overdose RiskNIHNational Institute of Nursing Research2022 to 2025$2,936,982September 26, 2022June 30, 2027EISENBERG, MATTHEWreporter.nih.gov
Identifying Suspected Drug Overdose Deaths in Near Real-Time Using Data Collected by Death InvestigatorsNIHNational Institute on Drug Abuse2022 to 2025$2,935,212September 30, 2022July 31, 2028HOCHSTATTER, KARLI RAEreporter.nih.gov
Ultra Wideband Fall Detection and Prediction Solution for People Living with DementiaNIHNational Institute on Aging2023 to 2025$2,930,322September 18, 2023August 31, 2026SYMONDS, SHELLEY Lreporter.nih.gov
Opioid and SUD Data Enclave (O-SUDDEn): Bringing real-time data to the opioid crisisNIHNational Institute on Drug Abuse2022 to 2025$2,921,106September 30, 2022August 31, 2027FERNANDEZ, SOLEDAD Areporter.nih.gov
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,919,684April 1, 2021March 31, 2026CULLEN, DANIEL KACYreporter.nih.gov
Assessing the Reach, Effectiveness, and Implementation of Multiple InterventionsNIHNational Institute on Drug Abuse2022 to 2025$2,900,711September 30, 2022July 31, 2027KRAL, ALEXANDER Hreporter.nih.gov
Preclinical Toxicology Study of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,885,957April 1, 2022August 31, 2027SUN, MIAOreporter.nih.gov
Functional Mechanism of Neural Control in Post-Concussion Convergence InsufficiencyNIHNational Eye Institute2021 to 2025$2,883,808April 1, 2014August 31, 2026ALVAREZ, TARA LYNNreporter.nih.gov
A youth-specific helmet for preventing traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023$2,864,855September 30, 2020August 31, 2025AVERY, GORDONreporter.nih.gov
DEVELOPMENT OF PLX-R18 CELL THERAPY AS A COUNTERMEASURE FOR HEMATOPOIETIC ACUTE RADIATION SYNDROMENIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,861,615July 1, 2023June 30, 2025FRANCO-YEHUDA, CHENreporter.nih.gov
Mitigating Injurious Falls in Older Adults Through Non-Injurious Fall and Gait Analysis From Floor VibrationsNIHNational Institute on Aging2021 to 2025$2,858,891September 30, 2018May 31, 2027FRITZ, STACY LYNNEreporter.nih.gov
Poly-omic predictors of symptom duration and recovery for adolescent concussionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,846,441January 1, 2020December 31, 2026HICKS, STEVEN DANIELreporter.nih.gov
Understanding the short- and long-term effects of disasters and other Big Events on the overdose crisisNIHNational Institute on Drug Abuse2023 to 2025$2,838,202September 30, 2023July 31, 2028MATTHAY, ELLICOTT COLSONreporter.nih.gov
Integrated Safety Optimization Services for People Who Use Drugs In Targeted Areas Of High Overdose RatesNIHNational Institute on Drug Abuse2022 to 2025$2,833,774September 30, 2022August 31, 2027JORDAN, AYANAreporter.nih.gov
From Neural Control of Movement to Treatments for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,832,066May 17, 2021April 30, 2029PEREZ, MONICA Areporter.nih.gov
Studying How State and Local Health Services Delivery Policies can Mitigate the Effects of Disasters on Drug Addiction Treatment and Overdose: A Mixed-Methods Study of COVID-19.NIHNational Institute on Drug Abuse2021 to 2024$2,829,066August 1, 2021May 31, 2026EISENBERG, MATTHEWreporter.nih.gov
Tailoring of cellular mechanical microenvironments to rescue age-related impairments in bone regenerationNIHNational Institute on Aging2022 to 2025$2,821,555September 30, 2022May 31, 2027MORGAN, ELISE Freporter.nih.gov
Clinically Significant Drug Interactions among Nursing Home Residents with ADRDNIHNational Institute on Aging2022 to 2025$2,819,494September 15, 2022May 31, 2027ZULLO, ANDREW REISreporter.nih.gov
Development of medication for the treatment of respiratory depression due to opioid (prescribed or illicit) overdose/multidrug (polysubstance) overdose in a hospital or community setting.NIHNational Institute on Drug Abuse2022 to 2025$2,818,821July 1, 2022December 31, 2026MILLER, THOMAS L.reporter.nih.gov
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) - Clinical Coordinating Center (CCC)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,815,025July 15, 2017January 31, 2028SILBERGLEIT, ROBERTreporter.nih.gov
Noninvasive Brain Stimulation for Treating Addiction (Supplement)NIHNational Institute on Drug Abuse2022 to 2024$2,814,672September 30, 2019August 31, 2025WAGNER, TIMOTHY ANDREWreporter.nih.gov
A Translational Evaluation of Sur1-Trpm4 Imaging Endophenotypes and Genetics to Direct Precision Medicine for Cerebral Edema After Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,799,271May 5, 2021April 30, 2027JHA, RUCHIRA MENKAreporter.nih.gov
The Importance of Abnormal Inflammasome Activation as a Risk Factor between Traumatic Brain Injury and Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,797,800September 20, 2021August 31, 2026DIETRICH, W DALTONreporter.nih.gov
Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Older Adults with DepressionNIHNational Institute on Minority Health and Health Disparities2021 to 2025$2,796,045June 26, 2015June 30, 2027CHOI, NAMKEE Greporter.nih.gov
Subconcussive neurodegenerative progression in adolescent athletesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,789,923December 15, 2020November 30, 2026KAWATA, KEISUKEreporter.nih.gov
Mobile health strategies to support longitudinal engagement in comprehensive, community-based prevention services for people who use drugsNIHNational Institute on Drug Abuse2022 to 2025$2,786,936September 30, 2022July 31, 2027WESTERGAARD, RYAN PATRICKreporter.nih.gov
Predict to Prevent: Dynamic Spatiotemporal Analyses of Opioid Overdose to Guide Pre-Emptive Public Health ResponsesNIHNational Institute on Drug Abuse2022 to 2025$2,786,810May 15, 2022March 31, 2027STOPKA, THOMAS Jreporter.nih.gov
Skeletal Health Outcomes among US Asian WomenNIHNational Institute on Aging2021 to 2025$2,781,738September 15, 2021June 30, 2027LO, JOAN Creporter.nih.gov
HIP fracture Accelerated surgical TreaTment And Care tracK-2 (HIP ATTACK-2) trialNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,781,673August 1, 2022July 31, 2027O'TOOLE, ROBERT V.reporter.nih.gov
Selective actin remodeling of sensory neurons for acute pain managementNIHNational Institute of Neurological Disorders and Stroke2023$2,776,138September 19, 2023August 31, 2025BLUM, PAULreporter.nih.gov
Weighting Longitudinal Data to Access Opioid Analgesia Tapering Outcomes among Patients with Co-occurring Chronic Pain and Substance Use DisorderNIHNational Institute on Drug Abuse2022 to 2025$2,773,978September 30, 2022July 31, 2027QEADAN, FARESreporter.nih.gov
Understanding the skeleton in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,772,646June 1, 2024May 31, 2027SUVA, LARRY J.reporter.nih.gov
Modulation of local adenosine signaling to attenuate fracture painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,768,294April 15, 2021March 31, 2027VARGHESE, SHYNIreporter.nih.gov
Mechanisms of Pain Associated with Trigeminal Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,760,934August 1, 2021June 30, 2027GOLD, MICHAEL Sreporter.nih.gov
Recovery among Older Adults Following Head InjuryNIHNational Institute on Aging2022 to 2025$2,752,989July 1, 2022March 31, 2027ALBRECHT, JENNIFER S.reporter.nih.gov
Opioid Policy ModelNIHNational Institute on Drug Abuse2021 to 2024$2,750,956April 1, 2020January 31, 2026BOBASHEV, GEORGIYreporter.nih.gov
Linking VA and non-VA data to study the risk of suicide in chronic pain patients.NIHNational Institute of Mental Health2021 to 2024$2,750,827August 10, 2020May 31, 2025PATHAK, JYOTISHMANreporter.nih.gov
PROMOTING T CELL RECOVERY AFTER RADIATION INJURY WITH LONG-ACTING INTERLEUKIN 7NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,749,087March 1, 2024February 28, 2026CHEN, BENNYreporter.nih.gov
Effectiveness of a CBT-based mHealth Intervention Targeting MOUD Retention, Adherence, and Opioid UseNIHNational Center for Complementary & Integrative Health2021 to 2024$2,748,195September 28, 2019November 30, 2025GLASNER, SUZETTE Vreporter.nih.gov
Resting State Connectivity in Primate Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,739,668February 15, 2016July 31, 2026GORE, JOHN Creporter.nih.gov
Development of FAST-DOSE assay system for the rapid assessment of acute radiation exposure, individual radiosensitivity and injury in victims for a large-scale radiological incidentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,738,709February 1, 2020January 31, 2026TURNER, HELEN Creporter.nih.gov
Mitigating neuroinflammation and enhancing neuronal integrity in Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$2,738,640September 30, 2022June 30, 2027MA, JIANJIEreporter.nih.gov
Cannabis use following trauma exposure: An observational study of the impact of acute stress and fear response on cannabis outcomesNIHNational Institute on Drug Abuse2022 to 2025$2,737,372August 15, 2022May 31, 2027NUGENT, NICOLE Rreporter.nih.gov
3D Models of the Blood-Brain Barrier for Studying Trauma-Induced Cerebral and Systemic InjuriesNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,735,039September 3, 2020August 31, 2025ZHENG, YINGreporter.nih.gov
Peer Engagement in Methamphetamine Harm-Reduction with Contingency Management (PEER-CM)NIHNational Institute on Drug Abuse2022 to 2025$2,732,822September 30, 2022July 31, 2027KORTHUIS, PHILIP TODDreporter.nih.gov
Platelets in radiation-induced immune dysregulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,721,709July 25, 2022May 31, 2027PATHAK, RUPAKreporter.nih.gov
Systems Genetics of Bone RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,717,663April 15, 2022January 31, 2027FARBER, CHARLES Rreporter.nih.gov
Effects of Noise Exposure Across the Lifespan on Balance and Stability in Older AdultsNIHNational Institute on Aging2021 to 2025$2,712,650September 30, 2021May 31, 2027STEWART, COURTNEY ELAINEreporter.nih.gov
COcoa Supplement and Multivitamins Outcomes Study (COSMOS): Effects on Falls and Physical PerformanceNIHNational Institute on Aging2021 to 2024$2,711,621May 15, 2021February 28, 2026LEBOFF, MERYL SUSANreporter.nih.gov
Community Driven Substance Use Recovery for High Opioid Overdose AreasNIHNational Institute on Drug Abuse2023 to 2025$2,706,416September 23, 2021May 31, 2027BELLAMY, CHYRELL DENISEreporter.nih.gov
Transcutaneous Phrenic Nerve Stimulation for Treating Opioid OverdoseNIHNational Institute on Drug Abuse2025$2,694,009September 1, 2023August 31, 2028LEVIN, HOWARDreporter.nih.gov
Standing Strong in Tribal Communities: Assessing Elder Falls DisparityNIHNational Institute on Minority Health and Health Disparities2021 to 2025$2,692,940April 21, 2021April 30, 2027SHAH, VALLABH Oreporter.nih.gov
Paired Brain and Spinal Cord Stimulation to Strengthen Spinal Sensorimotor CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,692,011December 15, 2020November 30, 2025CARMEL, JASON BRANTreporter.nih.gov
Modulating Exercise Dosage to Improve Concussion Rehabilitation: A Randomized Clinical TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,688,941May 15, 2022March 31, 2027HOWELL, DAVID R.reporter.nih.gov
SV2A PET in Spinal Cord Injury ImagingNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,688,423July 1, 2022June 30, 2027CAI, ZHENGXINreporter.nih.gov
Structural characterization of tau conformational heterogeneity in Down syndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,686,309August 1, 2025July 31, 2026SOUTHWORTH, DANIEL RYLANDreporter.nih.gov
Consortium Of MRI Biomarkers In Neonatal Encephalopathy (COMBINE)NIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,676,551May 1, 2022April 30, 2025GRANT, PATRICIA ELLENreporter.nih.gov
Study of Activity-Dependent Sympathetic SproutingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,675,718May 4, 2004June 30, 2026ZHANG, JUN-MINGreporter.nih.gov
Spinal cord injury causes liver pathology and metabolic dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,668,295April 1, 2021March 31, 2027MCTIGUE, DANA Mreporter.nih.gov
Central Nervous System Derived Exosomes: A Novel Source of Biomarkers for Neonatal Hypoxic Ischemic EncephalopathyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,664,241June 23, 2022March 31, 2027GOETZL, LAURAreporter.nih.gov
Development of negative allosteric modulators at the mu opioid receptorNIHNational Institute on Drug Abuse2025$2,664,000September 1, 2025August 31, 2027MAJUMDAR, SUSRUTAreporter.nih.gov
Amyloid-mediated cognitive dysfunction in bacterial pneumonia after TBINIHNational Institute on Aging2025$2,663,195September 15, 2025August 31, 2029WAGENER, BRANT Mreporter.nih.gov
Rehabilitation from Spinal Cord Injury Using Targeted, Activity-Dependent Intraspinal StimulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,662,265August 15, 2021July 31, 2026PERLMUTTER, STEVE Ireporter.nih.gov
A Longitudinal Qualitative Study of Fentanyl-Stimulant Polysubstance Use Among People Experiencing Homelessness (Administrative supplement)NIHNational Institute on Drug Abuse2022 to 2023$2,661,063November 1, 2023September 29, 2025MCNEIL, RYANreporter.nih.gov
identifying Concussed Adolescents at Risk for Emotional dysregulation 2 (iCARE2)NIHNational Institute of Mental Health2021 to 2025$2,660,976December 19, 2017May 31, 2029VERSACE, AMELIAreporter.nih.gov
Enhancing the function of hippocampal neurons after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,654,614June 1, 2021March 31, 2027DASH, PRAMOD Kreporter.nih.gov
The role of TMTC4, endoplasmic reticulum Ca2+ flux, and the unfolded protein response in noise-induced hearing lossNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,652,542October 1, 2023March 31, 2025CHAN, DYLANreporter.nih.gov
Identifying alcohol-related and built environment factors that can be modified to prevent pedestrian road traffic deathNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,645,973June 15, 2021March 31, 2026RUNDLE, ANDREW Greporter.nih.gov
CardioWatch: An Omics-Based Prediction Assay for Cardiac Late Effects ofAcute RadiationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,645,440July 1, 2020July 31, 2027KANHOLM, TOMASreporter.nih.gov
High Sensitivity Diffuse Optical Tomography of Human Brain FuncitonNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,642,789August 1, 2009November 30, 2026CULVER, JOSEPH Preporter.nih.gov
Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization InitiativeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,639,985September 30, 2020May 31, 2027HILLARY, FRANK GERARDreporter.nih.gov
Augmenting Implanted Neuroprosthetics with Targeted Health Monitoring for Spinal Cord Injury - the LIFELINENIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,632,178July 1, 2021March 31, 2026KILGORE, KEVIN L.reporter.nih.gov
A network-based, mixed methods study to identify and support multiple overdose responders and inform overdose prevention interventionsNIHNational Institute on Drug Abuse2022 to 2025$2,631,207September 30, 2022July 31, 2027WAGNER, KARLA D.reporter.nih.gov
Genetic Variation in Opioid Induced Respiratory Depression in MiceNIHNational Institute on Drug Abuse2021 to 2024$2,624,578April 1, 2020January 31, 2026BUBIER, JASON Areporter.nih.gov
Optimization of Bile Sequestrants to Treat Superwarfarin PoisoningNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,620,526September 20, 2022August 31, 2027FEINSTEIN, DOUGLAS L.reporter.nih.gov
Divergent age-dependent peripheral innate immune response following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,619,872July 1, 2021June 30, 2027THEUS, MICHELLE LEEreporter.nih.gov
Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal HydrocephalusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,613,622September 30, 2020April 30, 2030HWANG, MISUNreporter.nih.gov
Development of the anti-fentanyl monoclonal antibody, CSX-1004, for prophylaxis against fentanyl and fentanyl analog overdoseNIHNational Institute on Drug Abuse2025$2,612,736September 15, 2025July 31, 2028BARRETT, ANDREWreporter.nih.gov
Mitigating Injury Disparities with Evidence Based Trauma Systems PlanningNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,608,620September 24, 2023April 30, 2028JARMAN, MOLLY PRICEreporter.nih.gov
Mitochondrial Uncoupling Prodrug as a Translational Therapy for TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,607,985March 15, 2020July 31, 2026SULLIVAN, PATRICK Greporter.nih.gov
Dynamic Acellular Materials for Repairing Dense Connective TissuesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,603,489July 14, 2009April 30, 2030MAUCK, ROBERT Lreporter.nih.gov
Neurovascular unit dysfunction in Down syndrome revealed by TBINIHNational Institute of Neurological Disorders and Stroke2022$2,601,812September 7, 2022August 31, 2025HUANG, MINGXIAreporter.nih.gov
A randomized controlled trial of abdominal ultrasound (FAST) in children with blunt torso traumaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,596,438September 7, 2022August 31, 2027HOLMES, JAMES F.reporter.nih.gov
The Neurospan Bridge: A Device for Peripheral Nerve RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,594,464March 15, 2023August 31, 2027KOFFLER, YACOVreporter.nih.gov
Risk Factors for AIDS among persons who inject drugs: HIV transmission during and after the pandemicNIHNational Institute on Drug Abuse2021 to 2025$2,592,727September 10, 1994May 31, 2027MCKNIGHT, COURTNEYreporter.nih.gov
Prefrontal Anatomic Pathways in Executive ControlNIHNational Institute of Mental Health2021 to 2024$2,592,328July 1, 1987January 31, 2026BARBAS, HELENreporter.nih.gov
Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,591,324March 1, 2021February 28, 2027SHIN, SU RYONreporter.nih.gov
Image-guided, robot-assisted reduction of joint dislocation in orthopaedic surgeryNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,590,549September 1, 2021May 31, 2026UNERI, ALIreporter.nih.gov
Large Data Spatiotemporal Modeling of Optimal Combinations of Interventions to Reduce Opioid Harm in the United StatesNIHNational Institute on Drug Abuse2022 to 2025$2,586,219September 30, 2022June 30, 2027CERDA, MAGDALENAreporter.nih.gov
Microribbon scaffold-mediated Immunomodulation for Cranial Bone RepairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,582,020January 1, 2015May 31, 2027YANG, FANreporter.nih.gov
Rapid Low-Cost Quantitative 3D MRI and Gait Assessment of the KneeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,579,635August 15, 2020June 30, 2025HARGREAVES, BRIAN ANDREWreporter.nih.gov
Improving Access to Naloxone to Prevent Opioid Overdose Deaths Within Community-based Programs that Serve People Who Use DrugsNIHNational Institute on Drug Abuse2022 to 2025$2,575,705September 15, 2022June 30, 2027LAMBDIN, BARROT HOPKINSreporter.nih.gov
Development of a novel peptide therapeutic for traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,571,585February 3, 2025March 31, 2026MANN, AMANreporter.nih.gov
Regeneration of the Immune System after Radiation ExposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,571,006August 18, 2022June 30, 2027GUHA, CHANDANreporter.nih.gov
Using 3D Nonwovens Fabrication to Engineer Region-Specific Extracellular Matrix Structure and Bioactivity of the Knee MeniscusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,558,913July 1, 2021June 30, 2027FISHER, MATTHEW Breporter.nih.gov
Systemic Bone Loss Following Fracture in HumansNIHNational Institute on Aging2023 to 2025$2,557,825September 30, 2023May 31, 2028KAZAKIA, GALATEIA Jreporter.nih.gov
Impacts of Subsidized Ridesharing on Drunk Driving, Alcohol Consumption, and MobilityNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,557,446May 15, 2021September 30, 2025MORRISON, CHRISTOPHER NEILreporter.nih.gov
Modulated release of anti-senescence drugs to stimulate aged bone repairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,553,994June 1, 2012January 31, 2027KUHN, LIISA TIINAreporter.nih.gov
Mechanisms underlying extracellular vesicle mediated changes in inflammation, neural circuitry and plasticity following cortical injury in aged monkeysNIHNational Institute on Aging2022 to 2025$2,553,369July 15, 2022June 30, 2027MOORE, TARA Lreporter.nih.gov
IND-enabling development of a long-duration antagonist to treat opioid overdoseNIHNational Institute on Drug Abuse2023 to 2025$2,545,988September 15, 2023February 28, 2027ZANA, LAWRENCE Jreporter.nih.gov
Sex-based Muscular Adaptations, Capillary dysfunction and functional decline impact Knee-related psychosocial outcomes after acute knee injury (SMACK)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,544,899August 5, 2021May 31, 2027NOEHREN, BRIANreporter.nih.gov
Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,544,711March 15, 2020February 28, 2025DUFF, MELISSA Creporter.nih.gov
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,544,362December 1, 2021August 31, 2027SAYENKO, DIMITRYreporter.nih.gov
Role of disability and pain in opioid overdose: mechanism and risk mitigationNIHNational Institute on Drug Abuse2022 to 2025$2,540,888March 1, 2022January 31, 2027RUDOLPH, KARA ELIZABETHreporter.nih.gov
Multi-Center Clinical Trial of Spinal Cord Stimulation to Restore CoughNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,537,531September 22, 2022August 31, 2025DIMARCO, ANTHONY F.reporter.nih.gov
Diffusion MRI Model Parameter Estimation to Study Brain Microstructure as it Relates to Cognitive Status in Mild Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,534,685August 15, 2021July 31, 2025LUI, YVONNE Wreporter.nih.gov
Novel Therapeutic Agents to Reverse Opioid OverdoseNIHNational Institute on Drug Abuse2021 to 2022$2,529,335September 30, 2020August 31, 2025LI, XINHUAreporter.nih.gov
Resubmission: Structure/Function Determinants of Puncture Wound Thrombus FormationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,528,679September 1, 2021August 31, 2025STORRIE, BRIANreporter.nih.gov
Sustained Delivery of Tizanidine for Maintenance Treatment of Moderate to Severe SpasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,527,179April 15, 2019August 31, 2025WATKINS, GREGORYreporter.nih.gov
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,525,196August 1, 2020July 31, 2026GILMORE, EMILYreporter.nih.gov
Flexor tendon intrinsic healing and intervention strategy developmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,522,341July 1, 2021June 30, 2027ZHAO, CHUNFENGreporter.nih.gov
Clinically Assessed Risk Factors for a Second ACL Injury Using an Innovative Wearable SensorNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,520,372July 28, 2021May 31, 2027QUEEN, ROBIN Mreporter.nih.gov
Child Maltreatment and Risk for Mild Cognitive Impairment and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$2,519,932September 30, 2018May 31, 2025WIDOM, CATHY SPATZreporter.nih.gov
Neuronal and behavioral responses to spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,519,438March 1, 2015February 28, 2026DARIAN-SMITH, CORINNAreporter.nih.gov
Hip Fracture Pathology in Chronic Kidney DiseaseNIHNational Institute on Aging2021 to 2024$2,515,797March 1, 2020December 31, 2025HUGHES-AUSTIN, JAN MARIEreporter.nih.gov
Personalized Profiles of Pathology in Pediatric Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,515,544January 1, 2022November 30, 2026DENNIS, EMILY LARSENreporter.nih.gov
The Contribution of Repetitive Head Impacts and Social Determinants of Health to Alzheimer's Disease and Related Dementia in Older Adult Black MenNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,514,590August 15, 2023July 31, 2028TURNER, ROBERT W.reporter.nih.gov
Insurance-related barriers to medications for opioid use disorder in private and Medicaid plansNIHNational Institute on Drug Abuse2022 to 2025$2,512,669September 30, 2022July 31, 2027CHUA, KAO-PINGreporter.nih.gov
Neighborhood Risk Factors for Falls in the ElderlyNIHNational Institute on Aging2021 to 2024$2,509,021September 1, 2020April 30, 2025LI, WENJUNreporter.nih.gov
The inflammatory mechanisms underlying olfactory dysfunction in prognosis of TBI progression to dementiaNIHNational Institute on Aging2022 to 2025$2,508,327June 15, 2022March 31, 2027WU, JUNFANGreporter.nih.gov
Longitudinal Assessment of Driving After Mild TBI in TeensNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,507,174September 11, 2020July 31, 2026YANG, JINGZHEN GINGERreporter.nih.gov
Traumatic Brain Injury Anti-Seizure Prophylaxis in the Medicare ProgramNIHNational Institute on Aging2023 to 2025$2,504,051September 15, 2023May 31, 2028MOURA, LIDIA MARIA VERAS ROCHA DEreporter.nih.gov
Effects of Advanced Glycation Endproducts on Type 2 Diabetic and Fragility FracturesNIHNational Institute on Aging2022 to 2025$2,500,180August 1, 2022April 30, 2027VASHISHTH, DEEPAKreporter.nih.gov
Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive EnzymeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,493,979April 1, 2022March 31, 2027ALLEN, KYLE Dreporter.nih.gov
PRACT: A Pragmatic Randomized Adaptive Clinical Trial to Investigate Controlling Alcohol related harms in a Low-Income Setting; Emergency Department Brief Interventions in TanzaniaNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,490,756February 11, 2020January 31, 2026STATON, CATHERINE ANNreporter.nih.gov
Robust and Rapid 3D High-Resolution Cranial bone imaging for pediatric patients using MRINIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,488,491December 1, 2021November 30, 2026AN, HONGYUreporter.nih.gov
Take-home expansion: Scope and impact study (THESIS)NIHNational Institute on Drug Abuse2022 to 2025$2,483,369September 30, 2022June 30, 2027GRYCZYNSKI, JANreporter.nih.gov
Exploiting sex-dependent brain injury response for nanoparticle therapeuticsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,482,558January 1, 2021November 30, 2025STABENFELDT, SARAH Ereporter.nih.gov
Mobile Subthreshold Exercise Program for Concussion (M-STEP)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,482,057September 8, 2020August 31, 2025CHRISMAN, SARA P.D.reporter.nih.gov
Customizable cooperative multi-joint control to enhance walking mobility after strokeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,481,207September 15, 2022June 30, 2027MAKOWSKI, NATHANIEL STEVENreporter.nih.gov
Genetic dissection of trait variation between long-diverged mouse speciesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,481,029September 30, 2019June 30, 2025BREM, RACHEL BETHreporter.nih.gov
Bidirectional Brain-Gut interactions, chronic neuroinflammation and neurodegeneration after traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,480,051August 15, 2022July 31, 2027FADEN, ALAN IRAreporter.nih.gov
Using Structured Light Sensing with Machine Learning to Detect Unwitnessed In-Home FallsNIHNational Institute on Aging2023 to 2025$2,475,019February 15, 2020August 31, 2027GIBSON, PAULreporter.nih.gov
Multimodality Intervention to Improve Function and Metabolism in Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,474,995August 21, 2018April 30, 2024BHASIN, SHALENDERreporter.nih.gov
Novel mechanisms suppressing the pro-resolving phenotype of peripheral innate immunity following traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,473,913June 1, 2021March 31, 2027THEUS, MICHELLE LEEreporter.nih.gov
Testing the efficacy of a CBT-enhanced text message intervention to reduce symptom burden in individuals with post-traumatic stress disorder symptoms and co-occurring hazardous drinkingNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,473,236September 20, 2021August 31, 2027LINDGREN, KRISTEN Preporter.nih.gov
Novel Approaches to Opiate Use ReductionNIHNational Institute on Drug Abuse2021 to 2024$2,469,078April 1, 2020January 31, 2026HUTCHISON, KENT E.reporter.nih.gov
Blood test to aid treatment decisions for perinatal asphyxiationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,467,152January 1, 2020September 30, 2025STENGELIN, MARTINreporter.nih.gov
The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,466,010April 1, 2024August 31, 2026SCHWULST, STEVEN Jreporter.nih.gov
Brain lymphatic activation for craniosynostosis and Alzheimer’s diseaseNIHNational Institute of Neurological Disorders and Stroke2024$2,461,369June 1, 2024May 31, 2027CHEN, JIANFUreporter.nih.gov
Taking Our Shot: Extended-Release Naltrexone as Opioid Overdose Pre-Exposure Prophylaxis (PrEP) in People Using Stimulants Living With or At Risk of HIVNIHNational Institute on Drug Abuse2024$2,460,000July 1, 2024June 30, 2028APPA, AYESHA Areporter.nih.gov
Mechanisms of Blast-Induced Vestibular InjuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,459,906September 11, 2020August 31, 2025ZHU, HONGreporter.nih.gov
Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging - AD/ADRDNIHNational Institute on Aging2021 to 2023$2,458,774April 1, 2019January 31, 2025KACENA, MELISSA Areporter.nih.gov
Dysregulation of autophagy-lysosomal function links TBI to late-onset neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,458,515April 1, 2020March 31, 2026LIPINSKI, MARTA Mreporter.nih.gov
Respiratory interneuron circuit plasticity: promoting recovery of diaphragm function after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,455,409March 1, 2013April 30, 2028LEPORE, ANGELO C.reporter.nih.gov
mHealth-based Just-In-Time Adaptive Intervention to Improve Physical Activity Levels of Individuals with Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,452,410July 20, 2021December 31, 2026HIREMATH, SHIVAYOGI Vreporter.nih.gov
Regenerative Rehabilitation of Complex Musculoskeletal InjuriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,452,287April 1, 2016December 31, 2026GULDBERG, ROBERT Ereporter.nih.gov
EValuation Of Longitudinal outcomes in mild TBI Active-Duty Military and VEterans 10-YearNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,448,807April 1, 2015April 30, 2026MACDONALD, CHRISTINE Lreporter.nih.gov
Patterns and predictors of symptoms, falls, and functioning across treatment and recovery in patients treated with neurotoxic chemotherapy for cancerNIHNational Cancer Institute2021 to 2024$2,446,165September 10, 2020June 30, 2026WINTERS-STONE, KERRI Mreporter.nih.gov
Aging, macrophage mediators, and burn trauma: SupplementNIHNational Institute on Aging2021 to 2024$2,445,102February 1, 2001May 31, 2026KOVACS, ELIZABETH J.reporter.nih.gov
Trauma, the gut, and the brain: the gut microbiota-microglia axis in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,439,002August 1, 2022July 31, 2027SCHWULST, STEVEN Jreporter.nih.gov
BMP2 Regulation of Periosteal FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,436,018August 1, 2020April 30, 2026ROSEN, VICKIreporter.nih.gov
Trauma and Shock-Induced Microvascular Dysregulation and CoagulopathyNIHNational Institute of General Medical Sciences2022 to 2025$2,434,443March 1, 2022January 31, 2027KOZAR, ROSEMARY Areporter.nih.gov
von Willebrand Factor in Traumatic Brain Injury and Associated CoagulopathyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,120April 1, 2020March 31, 2025DONG, JING-FEIreporter.nih.gov
The Contribution of Age-Related Tauopathies to Alzheimer's DiseaseNIHNational Institute on Aging2023$2,430,703September 30, 2018August 31, 2026MCKEE, ANN C.reporter.nih.gov
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner ViolenceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,423,278January 15, 2021November 30, 2026ESOPENKO, CARRIE LYNNreporter.nih.gov
Adoption and Implementation of an Evidence-based Safe Driving Program for High-Risk Teen DriversNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,422,607September 8, 2020August 31, 2025YANG, JINGZHEN GINGERreporter.nih.gov
Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,420,406August 15, 2020July 31, 2025GRAHN, PETER JONASreporter.nih.gov
Immunomodulatory Therapy for Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,420,195September 1, 2018August 31, 2025CHEN, RIDONGreporter.nih.gov
Comparative Effectiveness and Safety of Osteoporosis Drug TherapiesNIHNational Institute on Aging2022 to 2025$2,418,555September 15, 2022June 30, 2027BRITO CAMPANA, JUAN Preporter.nih.gov
Modulation of signaling from damage-associated molecular patterns to improve radiation-induced thymic dysfunctionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,418,442July 18, 2022May 31, 2027DUDAKOV, JARRODreporter.nih.gov
Novel tools for in vitro electrophysiology and neurotrauma modelingNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,414,021August 17, 2020January 31, 2026FINAN, JOHN Dreporter.nih.gov
Pregnancy-associated mortality and morbidity due to drugs, self-harm, and violence in the United StatesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,412,869September 30, 2021August 31, 2025MARGERISON, CLAIRE Ereporter.nih.gov
ACTFAST: Urban and Rural Trauma Centers RE-AIM at Firearm Injury PreventionNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,401,338September 20, 2023April 30, 2028HOOPS, KATHERINEreporter.nih.gov
Evaluation of Trauma Center-Based, Technology-Enhanced Stepped Care Intervention for Adolescent Traumatic Injury SurvivorsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,399,996September 1, 2021August 31, 2025DAVIDSON, TATIANA MARGARITAreporter.nih.gov
Mechanisms of cochlear synaptopathy after noise or blast traumaNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,396,804January 1, 2020December 31, 2025OGHALAI, JOHN Sreporter.nih.gov
Acute predictors of long-term post-trauma outcomes in youth victims of violenceNIHNational Institute of Mental Health2021 to 2024$2,395,782August 13, 2020June 30, 2026LARSON, CHRISTINE Lreporter.nih.gov
2/2 Trauma Resuscitation with Group O Whole Blood or Products (TROOP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,395,733August 5, 2022July 31, 2027LEON-NOVELO, LUIS GONZALOreporter.nih.gov
A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury (SCI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,395,166September 15, 2020April 30, 2027LAD, SHIVANAND Preporter.nih.gov
Creating a novel place-based measure to explain geographic variability in naloxone access to reduce opioid overdose deathsNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,391,879September 26, 2022June 30, 2027CARPENTER, DELESHA MILLERreporter.nih.gov
OpenSim Enhancements to Enable Computational Design of Personalized Treatments for Movement ImpairmentsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,391,188September 6, 2021May 31, 2026FREGLY, BENJAMIN Jreporter.nih.gov
Propriopsinal neuron function in normal and post-SCI locomotionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,389,077March 15, 2021January 31, 2027MAGNUSON, DAVID SKreporter.nih.gov
Building and implementing a TBI prognostic model featuring real-time analysis of brain CT imagesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,387,866June 1, 2022May 31, 2027DUNN, TIMOTHY WILLIAMreporter.nih.gov
Assessing the Impact of Emergency Medical Services System Changes to Overdose Response: The ORCID StudyNIHNational Institute on Drug Abuse2023 to 2025$2,386,732September 1, 2023July 31, 2028VAN DRAANEN, JENNAreporter.nih.gov
Multi-organ human-on-a-chip system to address overdose and acute and chronic efficacy and off-target toxicityNIHNational Center for Advancing Translational Sciences2021$2,381,424September 27, 2019July 31, 2025HICKMAN, JAMES Jreporter.nih.gov
Toxicology and Efficacy Studies of Intrathecal VersaMab-101 for spinal cord injury treatmentNIHNational Institute of Neurological Disorders and Stroke2023$2,380,552September 18, 2023August 31, 2026SUN, MIAOreporter.nih.gov
A randomized controlled trial of an innovative in-home rehabilitation program for persons with TBI and their families: Home-based Occupational-therapy and Management of the Environment (HOME for Us)NIHNational Institute of Nursing Research2021 to 2024$2,379,845September 15, 2020June 30, 2026MORIARTY, HELENE JOYreporter.nih.gov
Cxcl12-Hedgehog signaling in cranial bone regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,375,113July 5, 2016June 30, 2027YANG, YINGZIreporter.nih.gov
Deconstructing Cartilage Mechanotransduction by Piezo ChannelsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,369,902June 2, 2021July 31, 2025GUILAK, FARSHIDreporter.nih.gov
Mechanisms of Circadian and Synaptic Dysfunction After Repetitive Mild TBINIHNational Institute of Neurological Disorders and Stroke2022$2,366,184June 1, 2022May 31, 2025WHALEN, MICHAEL Jreporter.nih.gov
Traumatic Axonopathy in the CNS as Wallerian degenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,365,581January 1, 2021November 30, 2026KOLIATSOS, VASSILIS Ereporter.nih.gov
Development of a minimally invasive biomarker assay to detect delayed radiation injuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,365,409February 1, 2020January 31, 2026BOERMA, MARJANreporter.nih.gov
Investigation of the Central and Peripheral Inflammatory Mechanisms of PTSD OnsetNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,362,581September 1, 2021August 31, 2025GILL, JESSICA MARYreporter.nih.gov
Kentucky Outreach Service Kiosk (KyOSK): Reducing Overdose, Hepatitis C, and Other Drug-related Risks in Rural Appalachia through Health KiosksNIHNational Institute on Drug Abuse2022 to 2025$2,359,307August 15, 2022June 30, 2027YOUNG, APRIL MARIEreporter.nih.gov
Gut pathogen virulence and its therapeutic modulation during surgical injuryNIHNational Institute of General Medical Sciences2021 to 2025$2,357,080February 1, 2001March 31, 2027ALVERDY, JOHN Creporter.nih.gov
Toolkit for Optimal Recovery after Orthopedic Injury; A multi-site feasibility study to prevent persistent pain and disabilityNIHNational Center for Complementary & Integrative Health2021 to 2023$2,355,817May 1, 2020April 30, 2025VRANCEANU, ANA-MARIAreporter.nih.gov
Predicting fatal and non-fatal overdose in Los Angeles County with Rapid Overdose Surveillance Dashboard to target street-based addiction treatment and harm reduction servicesNIHNational Institute on Drug Abuse2022 to 2025$2,355,267September 30, 2022August 31, 2027SHOVER, CHELSEA LEIGHreporter.nih.gov
3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,352,214September 2, 2021June 30, 2026PARR, ANN Mreporter.nih.gov
Detect: A novel device to assess how HIV affects neurocognitive decline and postural instability in older adults at risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$2,349,852February 15, 2019November 30, 2024MOORE, RAEANNE CRISTINEreporter.nih.gov
Examining the Impact of the Twin Epidemics of Methamphetamine and Opioid Use on Overdose, Risky Sex and Treatment Engagement among PWUD in Two Rural Appalachian CohortsNIHNational Institute on Drug Abuse2021 to 2024$2,345,140September 1, 2012March 31, 2028HAVENS, JENNIFER Rreporter.nih.gov
Enhancing recovery of lower limb function after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,341,089September 1, 2024August 31, 2026RENNAKER, ROBERT Lreporter.nih.gov
An Innovative, Prospective Model to Understand Risk and Protective Factors for Sexual Assault Experiences and Outcomes Among Sexual Minority MenNIHNational Institute on Minority Health and Health Disparities2022 to 2024$2,340,662July 22, 2022December 31, 2024EDWARDS, KATIE Mreporter.nih.gov
Developmental Origin, Injury and Epigenomic Regulation of NF1-Associated Peripheral Nerve Sheath TumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,339,120April 15, 2021June 30, 2024ZHU, YUANreporter.nih.gov
PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,336,406September 20, 2014June 30, 2026KANAI, ANTHONY JOHNreporter.nih.gov
The effectiveness of text-based messaging strategies for preventing subsequent problematic alcohol use among technical trainees in the U.S. Air forceNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,336,405September 12, 2022August 31, 2027WISEMAN, KARA Preporter.nih.gov
Optimization of AEOL10150 treatment of sulfur mustard-induced lung toxidrome in a pig modelNIHNational Institute of Environmental Health Sciences2021 to 2023$2,332,659September 1, 2018May 31, 2025DAY, BRIAN Jreporter.nih.gov
Community-Based Opioid Treatment (CBOT): Development and testing of a novel nurse-led model to deliver opioid use disorder treatment and HIV prevention and care in the community setting.NIHNational Institute on Drug Abuse2025$2,332,500June 15, 2025May 31, 2029HEIDARI, OMEIDreporter.nih.gov
Using Re-inforcement Learning to Automatically Adapt a Remote Therapy Intervention (RTI) for Reducing Adolescent Violence InvolvementNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,323,684September 1, 2023March 31, 2024CARTER, PATRICK M.reporter.nih.gov
Examining the synergistic effects of cannabis and prescription opioid policies on chronic pain, opioid prescribing, and opioid overdoseNIHNational Institute on Drug Abuse2021 to 2023$2,319,128January 1, 2019November 30, 2025CERDA, MAGDALENAreporter.nih.gov
Assessing Diffusion MRI Metrics for Detecting Changes of Synaptic Density in Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$2,313,017September 15, 2023May 31, 2028WU, YU-CHIENreporter.nih.gov
Extrinsic Mechanisms Governing Injury-Induced Axon DegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,312,486August 15, 2015March 31, 2026DEPPMANN, CHRISTOPHER Dreporter.nih.gov
Pulsed laser therapy in an asymptomatic head injury-accelerated Alzheimer's modelNIHNational Institute of Neurological Disorders and Stroke2024$2,309,898September 17, 2024August 31, 2027ZHANG, QUANGUANGreporter.nih.gov
Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric SymptomsNIHNational Institute of Neurological Disorders and Stroke2021$2,309,451September 15, 2021August 31, 2024ALOSCO, MICHAELreporter.nih.gov
Regulation of Peripheral Neuropathic Pain by B CellsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,308,227March 15, 2022February 28, 2027GRACE, PETER Mreporter.nih.gov
Neuromechanisms of falls in older adults with MCI: Targeting assessment and training of reactive balance controlNIHNational Institute on Aging2021 to 2024$2,306,203September 5, 2021August 31, 2026BHATT, TANVIreporter.nih.gov
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021$2,302,768April 1, 2021March 31, 2024ZHAO, ZHENreporter.nih.gov
Sexual Assault Recovery Among Sexual Minority Women: A Longitudinal, Multi-Level StudyNIHNational Institute on Minority Health and Health Disparities2023 to 2025$2,302,730May 9, 2023March 20, 2028BEDARD-GILLIGAN, MICHELE Areporter.nih.gov
Reprogramming proinflammatory microglia by restoring mitochondrial functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,300,527July 1, 2020June 30, 2025POLSTER, BRIAN Mreporter.nih.gov
A Near-Patient, Low Blood Volume Platform for Rapid Comprehensive Evaluation of Coagulation in Trauma PatientsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,298,252April 10, 2023July 31, 2027PAMULA, VAMSEE K.reporter.nih.gov
Contribution of Innate Immune Receptors to Neurological Dysfunction After Traumatic Brain Injury: Mechanisms and Therapeutic ImplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,291,943April 1, 2021March 31, 2027SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
The mechanism of allosteric modulation of glutamate transportersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,281,652December 1, 2019November 30, 2025MORTENSEN, ANDREIA C Kreporter.nih.gov
A Novel Semi-autonomous Surgeon-in-the-loop in situ Robotic Bioprinting System for Functional and Cosmetic Restoration of Volumetric Muscle Loss InjuriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,279,838September 1, 2022August 31, 2027ALAMBEIGI, FARSHIDreporter.nih.gov
Optimizing Collaborative Care for Youth with Persistent Post-Concussive SymptomsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,275,364February 3, 2017April 30, 2028MC CARTY, CAROLYN Areporter.nih.gov
A Novel Bone Targeted Antibiotic Therapy for the Treatment of Infected FracturesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,268,141April 22, 2024March 31, 2027EBETINO, FRANK H.reporter.nih.gov
Focused ultrasound-induced cavitation in elastic, anisotropic tissues: a treatment for tendinopathiesNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,264,833September 21, 2022June 30, 2027SIMON, JULIANNAreporter.nih.gov
Druggable Mitochondrial Targets for Treatment of Cerebral IschemiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,263,870February 1, 2020January 31, 2026CLARK, ROBERT S Breporter.nih.gov
The Impact of Community Infrastructure Reinvestment Programs on Opioid Misuse and Opioid OverdoseNIHNational Institute on Drug Abuse2023 to 2025$2,257,300September 30, 2023August 31, 2028NESOFF, ELIZABETHreporter.nih.gov
Mechanisms of oxysterol-induced oligodendrogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,255,433December 15, 2019November 30, 2024BENNER, ERIC Jreporter.nih.gov
Impact of prescription stimulants on the drug overdose epidemicNIHNational Institute on Drug Abuse2023 to 2025$2,253,245May 1, 2023March 31, 2028DE NADAI, ALESSANDRO STEVENSreporter.nih.gov
Precision Medicine Approach: Using genomic information to guide TBI treatmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,251,700January 15, 2020December 31, 2025GOMEZ-PINILLA, FERNANDOreporter.nih.gov
Tympanic membrane progenitor cells in homeostasis in injuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,250,702April 25, 2020March 31, 2026TWARD, AARONreporter.nih.gov
Elution of a Small Molecule from a Bio Ceramic Collagen Bone Graft Device Heals Bone while InhibitingBreast Cancer Bone MetastasesNIHNational Cancer Institute2021 to 2022$2,249,777November 30, 2021August 31, 2022MARGULIES, BRYAN SAMUELreporter.nih.gov
Exploring the EphB2-NMDA receptor interaction in spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,249,630September 1, 2018June 30, 2029LEPORE, ANGELO C.reporter.nih.gov
Validation of neuronal senescence as a target for chronic pain in agingNIHNational Institute on Aging2024$2,249,392September 15, 2024August 31, 2027TAWFIK, VIVIANNE Lreporter.nih.gov
Firearm violence prevention through community-engaged vacant property reuse: Application of Busy Streets Theory in DetroitNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$2,247,415September 17, 2021August 31, 2025HEINZE, JUSTIN EDWARDreporter.nih.gov
Improving Outcomes for Care Partners of Persons with Traumatic Brain InjuryNIHNational Institute of Nursing Research2021 to 2024$2,247,328September 27, 2012November 30, 2025CARLOZZI, NOELLE E.reporter.nih.gov
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and TraumaNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$2,244,008September 1, 2023August 31, 2028ANDERSON, MELISSA LEEreporter.nih.gov
The Rhode Island Young Adult Prescription and Illicit Drug Study (RAPIDS): Responding to Fentanyl and Associated HarmsNIHNational Institute on Drug Abuse2021 to 2023$2,243,163August 15, 2019May 31, 2025MARSHALL, BRANDON DAVID LEWISreporter.nih.gov
Arthroscopic Raman Monitoring of Cartilage Content for PTOA Diagnosis and Chondroregenerative Treatment ResponseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,239,693August 2, 2022May 31, 2027ALBRO, MICHAEL Breporter.nih.gov
Stabilizing the Tripartite Synaptic Complex Following TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,237,377February 1, 2017December 31, 2027LIEBL, DANIEL JONreporter.nih.gov
Reducing Drug-Related Mortality Using Predictive Analytics: A Randomized, Statewide, Community Intervention TrialNIHNational Institute on Drug Abuse2021 to 2023$2,236,493September 30, 2019July 31, 2025MARSHALL, BRANDON DAVID LEWISreporter.nih.gov
MRI Measurement of the Mechanical Vulnerability of the BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,235,019September 15, 2019July 31, 2025BAYLY, PHILIP Vreporter.nih.gov
The Function and Mechanisms of Autophagy in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2022$2,231,793June 1, 2016May 31, 2025WU, JUNFANGreporter.nih.gov
Autocrine Action of Elevated FGF-21 Contributing to Skeletal Muscle Atrophy in Response to Mitochondrial DysfunctionNIHNational Institute on Aging2021 to 2025$2,229,824August 15, 2021April 30, 2027ROWE, GLENN CAMERONreporter.nih.gov
Reparative effect of juvenile factors in aging and injuryNIHNational Institute on Aging2022 to 2025$2,224,311June 15, 2022February 28, 2027RAJU, RAGHAVAN PILLAIreporter.nih.gov
Spinal Effects of Cortical Stimulation: Mechanisms and Functional ImpactNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,222,374September 30, 2019July 31, 2025WOLPAW, JONATHAN RICKELreporter.nih.gov
Roles of Collagen and Water in the Fracture Resistance of BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,220,473September 1, 2012May 31, 2027NYMAN, JEFFRY STEPHENreporter.nih.gov
Heading and Soccer: Understanding Cognitive Risks, Benefits, and the Potential Mediating Role of White MatterNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,220,345August 1, 2022July 31, 2027LIPTON, MICHAEL LAWRENCEreporter.nih.gov
Spatiotemporal Molecular Substrates of TBI at Single Cell ResolutionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,218,963July 1, 2020March 31, 2026YANG, XIAreporter.nih.gov
Notch signaling and Bone Fracture HealingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,213,436February 1, 2011January 31, 2027KALAJZIC, IVOreporter.nih.gov
Limb coordination during locomotion before and after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,207,839February 15, 2020January 31, 2026RYBAK, ILYA Areporter.nih.gov
Prospective Validation of Neurophysiologic Outcome Prediction in Acute Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,202,008January 1, 2023December 31, 2027WESTOVER, MICHAEL BRANDONreporter.nih.gov
Development of KCC2 Neuromodulators to Treat Paralysis After Spinal Cord Injury.NIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,200,694March 1, 2022February 28, 2025STANICKA, JOANNAreporter.nih.gov
Neuroprotective B Cell Immunotherapy for Contusion Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,197,906May 1, 2021February 28, 2027SIRBULESCU, RUXANDRA Freporter.nih.gov
Improving intracortical control of reaching after paralysisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,197,457July 1, 2020June 30, 2026TAYLOR, DAWN MARIEreporter.nih.gov
Development of Molecular Probe Inhibitors of Pathogenic, Cytosolic Cathespin B in Traumatic Brain Injury and Alzheimers Disease NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,197,366August 1, 2019June 30, 2025HOOK, VIVIAN Y. Hreporter.nih.gov
Role of Stress Granule Protein Aggregation in Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,196,651July 1, 2020June 30, 2026TWISS, JEFFERY Lreporter.nih.gov
Cellular signaling mechanisms that drive persistent hyperexcitability in nociceptorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,193,348August 15, 2015July 31, 2030DESSAUER, CARMEN W.reporter.nih.gov
Pathways underlying recovery of injured urethral sphincter and a novel regenerative biomaterial interventionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,191,647July 15, 2021April 30, 2026ALPERIN, MARIANNAreporter.nih.gov
Alcohol and Burn Trauma: Multi-organ Inflammatory ResponsesNIHNational Institute of General Medical Sciences2021 to 2025$2,191,572September 20, 2019June 30, 2029KOVACS, ELIZABETH J.reporter.nih.gov
Endocannabinoid Targeting for Opioid Induced Respiratory DepressionNIHNational Institute on Drug Abuse2022 to 2025$2,190,554July 1, 2022June 30, 2027MILNES, TALLY MARIEreporter.nih.gov
Reversing Overdose Epidemics through Simulation, Collaboration, and Unified Efforts (RESCUE)NIHNational Institute on Drug Abuse2024 to 2025$2,189,222September 15, 2024July 31, 2028ZANG, XIAOreporter.nih.gov
A quantitative framework to examine sex differences in musculoskeletal scaling and functionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,184,931September 1, 2021August 31, 2026BLEMKER, SILVIA SALINASreporter.nih.gov
Modification of Post-Traumatic Osteoarthritis Progression with Joint UnloadingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,182,992March 1, 2020November 30, 2025CHRISTIANSEN, BLAINE A.reporter.nih.gov
Myeloid lineage targeting to improve recovery from injury and surgery: Cellular and molecular mechanismNIHNational Institute of General Medical Sciences2021 to 2025$2,181,628September 15, 2020July 31, 2030TAWFIK, VIVIANNE Lreporter.nih.gov
Assessing the effects of peripheral immune activation on the NVU following TBI using a vascularized and perfused human blood/BBB modelNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,181,059September 15, 2021August 31, 2026AGALLIU, DRITANreporter.nih.gov
Digital Biomarkers of Post-traumatic Osteoarthritis: Toward Precision RehabilitationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,179,833September 1, 2022August 31, 2027HALILAJ, ENIreporter.nih.gov
Wireless Implantable COrtical Neuroprosthetic System (W-ICONS)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,177,031June 1, 2023May 31, 2026TENORE, FRANCESCO Vreporter.nih.gov
Probing Osteoarthritis Pathogenesis by Noninvasive Imaging of Cartilage StrainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$2,176,180September 19, 2013March 31, 2025NEU, COREY Preporter.nih.gov
Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolismNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,169,572September 1, 2020August 31, 2025PARK, JAE MOreporter.nih.gov
An immunomodulatory approach to improve oral cavity wound healingNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,169,288April 1, 2020March 31, 2025GOUDY, STEVEN Lreporter.nih.gov
Chronic and Evolving Inflammation after Traumatic Brain Injury: Microglial Priming and Neuropsychiatric ComplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,169,210April 1, 2021March 31, 2026GODBOUT, JONATHAN Preporter.nih.gov
Targeting angiogenesis for fracture nonunion treatment under inflammatory diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,165,056September 9, 2020June 30, 2027SHEN, JIEreporter.nih.gov
Rewiring the Injured Brain with GABA ProgenitorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,163,757February 15, 2016March 31, 2027HUNT, ROBERT Freporter.nih.gov
Moving Upstream: Understanding Racism, Firearm Injury Risks, and Resiliency Among Asian AmericansNIHNational Institute of Nursing Research2022$2,162,049September 15, 2022June 30, 2025HSIEH, HSING-FANGreporter.nih.gov
Creating Peace: community-based youth violence prevention to address racism and discriminationNIHNational Institute on Minority Health and Health Disparities2021 to 2023$2,161,114May 24, 2019January 31, 2026MILLER, ELIZABETHreporter.nih.gov
Social and behavioral determinants of MOUD utilization and opioid overdoseNIHNational Institute on Drug Abuse2023 to 2025$2,158,035August 1, 2023May 31, 2028YU, HONGreporter.nih.gov
Using human skin grafted mice to identify biomarkers of exposure and study effects of radiation on skinNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,157,978February 21, 2020January 31, 2025CLARK, RACHAEL ANNreporter.nih.gov
Adaptation of internal motor copy circuits in recovery after spinal cord injury.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,157,453August 1, 2020June 30, 2025SMITH, GEORGE Mreporter.nih.gov
Impacts of structural and system-level interventions on HIV/STI and overdose epidemics among SWsNIHNational Institute on Drug Abuse2021 to 2024$2,156,134July 15, 2010March 31, 2026KRUSI, ANDREAreporter.nih.gov
Maternal Antecedents and Electronic Fetal Monitoring in Term Asphyxia (MAESTRA)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,155,884May 1, 2020December 31, 2026WU, YVONNE Wreporter.nih.gov
Improvement of Organ Function after Severe HypovolemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,155,286February 1, 2004December 31, 2026WANG, PINGreporter.nih.gov
Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2022$2,152,606August 1, 2016August 31, 2025RANUM, LAURA P.Wreporter.nih.gov
Enhancing Infrastructure for Clinical and Translational Research to Address the Opioid EpidemicNIHNational Center for Advancing Translational Sciences2021 to 2023$2,152,222August 6, 2019June 30, 2024LENERT, LESLIE A.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Pittsburgh at PittsburghPittsburgh, PA85$115 million0$0
University of WashingtonSeattle, WA67$97.2 million0$0
University of KentuckyLexington, KY50$96 million0$0
Ohio State UniversityColumbus, OH64$93.6 million0$0
University of Michigan at Ann ArborAnn Arbor, MI68$90.8 million0$0
Johns Hopkins UniversityBaltimore, MD71$87.3 million0$0
University of PennsylvaniaPhiladelphia, PA69$78.4 million0$0
Washington UniversitySaint Louis, MO64$76.7 million0$0
University of California, San DiegoLa Jolla, CA43$69.7 million0$0
University of California, San FranciscoSan Francisco, CA57$66.5 million0$0
Massachusetts General HospitalBoston, MA46$64.4 million0$0
Yale UniversityNew Haven, CT38$61.9 million0$0
University of Maryland BaltimoreBaltimore, MD42$61.9 million0$0
Duke UniversityDurham, NC60$60.7 million0$0
University of California Los AngelesLos Angeles, CA39$60.3 million0$0
University of FloridaGainesville, FL44$57.4 million0$0
New York University School of MedicineNew York, NY36$51.3 million0$0
Boston University Medical CampusBoston, MA36$50.2 million0$0
Columbia University Health SciencesNew York, NY36$48.6 million0$0
University of Colorado DenverAurora, CO42$46.8 million0$0
Wake Forest University Health SciencesWinston-Salem, NC25$38 million0$0
Boston Medical CenterBoston, MA9$37.7 million0$0
Research Triangle InstituteResearch Triangle Park, NC12$36.4 million0$0
Columbia UniversityNew York, NY4$36 million0$0
University of UtahSalt Lake City, UT27$36 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX30$36 million0$0
Brigham and Women's HospitalBoston, MA30$35.9 million0$0
University of ChicagoChicago, IL15$35.8 million0$0
Oregon Health & Science UniversityPortland, OR30$33 million0$0
University of MinnesotaMinneapolis, MN27$32.4 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY18$31.3 million0$0
University of Alabama at BirminghamBirmingham, AL26$29.2 million0$0
Drexel UniversityPhiladelphia, PA29$28.9 million0$0
Mayo Clinic RochesterRochester, MN21$28.8 million0$0
University of Mississippi Med CTRJackson, MS6$28.8 million0$0
Ut Southwestern Medical CenterDallas, TX26$28.7 million0$0
University of Southern CaliforniaLos Angeles, CA25$27.9 million0$0
Brown UniversityProvidence, RI19$27.6 million0$0
Stanford UniversityStanford, CA30$27.5 million0$0
Northwestern University at ChicagoChicago, IL30$27.2 million0$0
Vanderbilt University Medical CenterNashville, TN20$26.8 million0$0
Case Western Reserve UniversityCleveland, OH23$26.3 million0$0
Emory UniversityAtlanta, GA30$26.1 million0$0
California Pacific Med CTR Res InstituteSan Francisco, CA2$25.4 million0$0
Rhode Island HospitalProvidence, RI18$24.3 million0$0
University of Miami School of MedicineCoral Gables, FL23$23.9 million0$0
University of VirginiaCharlottesville, VA14$23.7 million0$0
University of Wisconsin-MadisonMadison, WI26$23.1 million0$0
University of Texas HLTH Science CenterSan Antonio, TX14$22.7 million0$0
Weill Medical Coll of Cornell UnivNew York, NY18$22.4 million0$0
University of LouisvilleLouisville, KY18$21.7 million0$0
Indiana University IndianapolisIndianapolis, IN23$21.7 million0$0
Medical University of South CarolinaCharleston, SC18$21.6 million0$0
Virginia Commonwealth UniversityRichmond, VA20$21.5 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA19$21.2 million0$0
Albert Einstein College of MedicineBronx, NY11$20.4 million0$0
University of Illinois at ChicagoChicago, IL22$19.9 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC28$19.6 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA15$19.5 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ13$19 million0$0
University of ArizonaTucson, AZ20$19 million0$0
University of RochesterRochester, NY21$18.9 million0$0
Medical College of WisconsinMilwaukee, WI25$18.5 million0$0
Boston Children's HospitalBoston, MA16$17.8 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM7$17.8 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR12$17.3 million0$0
University of California at DavisDavis, CA15$17.2 million0$0
Augusta UniversityAugusta, GA15$16.9 million0$0
Research Inst Nationwide Children's HospColumbus, OH14$16.7 million0$0
Seattle Children's HospitalSeattle, WA9$15.5 million0$0
Ensysce Biosciences, Inc.La Jolla, CA2$15.4 million0$0
University of Connecticut SCH of Med/dntFarmington, CT18$15.1 million0$0
University of California-IrvineIrvine, CA16$14.6 million0$0
University of Vermont & ST Agric CollegeBurlington, VT9$14.5 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA15$14.4 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH13$14.3 million0$0
University of CincinnatiCincinnati, OH15$13.3 million0$0
Kaiser Foundation Research InstituteOakland, CA5$13.2 million0$0
University of Colorado at BoulderBoulder, CO7$13 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA11$12.8 million0$0
University of Texas Med BR GalvestonGalveston, TX12$12.4 million0$0
Rehabilitation Institute of Chicago D/b/a Shirley Ryan AbilitylabChicago, IL12$12.3 million0$0
Hebrew Rehabilitation Center for AgedBoston, MA7$12 million0$0
George Washington UniversityWashington, DC8$12 million0$0
Indiana UniversityBloomington, IN8$11.7 million0$0
University of Wisconsin-MilwaukeeMilwaukee, WI5$11.2 million0$0
Trustees of Boston UniversityBoston, MA7$11.1 million0$0
Salk Institute for Biological StudiesLa Jolla, CA4$11.1 million0$0
Florida International UniversityMiami, FL3$10.8 million0$0
North Carolina State UniversityRaleigh, NC9$10.6 million0$0
Laureate Institute for Brain ResearchTulsa, OK1$10.3 million0$0
Arizona State UniversityScottsdale, AZ9$10.2 million0$0
University of Texas at AustinAustin, TX8$10.1 million0$0
Georgia State UniversityAtlanta, GA10$10 million0$0
Revbio, Inc.Lowell, MA5$9.9 million0$0
Friends Research Institute, Inc.Baltimore, MD5$9.2 million0$0
University of DelawareNewark, DE13$9 million0$0
SUNY at Stony BrookStony Brook, NY5$9 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA7$9 million0$0
Lurie Children's Hospital of ChicagoChicago, IL4$8.9 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,446$778,867,2440$0
20241,533$804,103,0950$0
20231,541$796,482,4380$0
20221,476$826,397,7430$0
20211,432$799,111,3780$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 15 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 7 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 2 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIHMay 7, 2027Not listedNotice number printed on 1 award here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIHJanuary 7, 2027$375,000Notice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 918 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 918 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 918 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 918 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 918 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 918 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 918 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 918 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 918 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 918 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.