Data / Research funding / Osteoarthritis
Osteoarthritis: 540 NIH awards ($598M) to 163 organizations
540 NIH awards ($598M) in the NIH spending category Osteoarthritis, to 163 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
The 500 largest of 540 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $19,316,294 | January 1, 2021 | July 31, 2026 | FAVA, MAURIZIO | reporter.nih.gov |
| Mapping the joint-nerve interactome of the knee | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $11,877,917 | September 23, 2022 | August 31, 2027 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Center for Musculoskeletal Disease Research (CMDR) | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $11,683,826 | February 16, 2018 | January 31, 2028 | O'BRIEN, CHARLES A | reporter.nih.gov |
| Innervation of the knee and TMJ | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $10,814,779 | September 23, 2022 | August 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Increasing the Efficiency of RE-JOIN Through Data Sharing and Integration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $10,788,004 | September 23, 2022 | July 31, 2027 | LEE, BRENDAN | reporter.nih.gov |
| A sequenced-strategy for improving outcomes in patients with knee osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $10,487,739 | September 25, 2019 | August 31, 2025 | CAMPBELL, CLAUDIA MICHELLE | reporter.nih.gov |
| The Osteoarthritis Prevention Study (TOPS) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $7,779,027 | August 10, 2023 | July 31, 2028 | MESSIER, STEPHEN P | reporter.nih.gov |
| Daily & Localized NSAID Sonophoresis for Symptomatic Treatment of Knee Osteoarthritis | NIH | National Institute on Aging | 2021 to 2025 | $7,422,310 | September 20, 2024 | May 31, 2027 | LEWIS, GEORGE KENNETH | reporter.nih.gov |
| Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic Trial | NIH | National Center for Complementary & Integrative Health | 2024 to 2025 | $5,587,756 | May 19, 2023 | August 31, 2028 | WANG, CHENCHEN | reporter.nih.gov |
| Leveraging inter-individual differences in walking pain and impairment to elucidate whole-person mechanisms of knee osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $4,899,748 | September 19, 2025 | August 31, 2029 | ALTER, BENEDICT J | reporter.nih.gov |
| Network modeling as a unified framework to understand inter-individual differences in chronic musculoskeletal pain | NIH | National Center for Complementary & Integrative Health | 2025 | $4,649,740 | August 15, 2025 | July 31, 2029 | SIKDAR, SIDDHARTHA | reporter.nih.gov |
| Clinical Optimization of Ultrasonic Drug Delivery Technologies for US Veteran Populations that Experience Health Disparities with Arthritis and Chronic Pain | NIH | National Institute on Minority Health and Health Disparities | 2023 to 2025 | $4,518,543 | September 14, 2020 | February 28, 2026 | LEWIS, GEORGE KENNETH | reporter.nih.gov |
| Small molecule targeting an epigenetic regulator for the treatment of osteoarthritis | NIH | National Institute on Aging | 2021 to 2024 | $4,178,124 | September 30, 2021 | May 2, 2025 | ADORNO, MADDALENA | reporter.nih.gov |
| Elucidating Factors Contributing to Disparities in Neurobiological Vulnerabilities and Alzheimers Disease and Related Dementias Risk | NIH | National Institute on Aging | 2021 to 2023 | $4,137,397 | April 1, 2009 | February 28, 2025 | FILLINGIM, ROGER B | reporter.nih.gov |
| Osteoarthritis Progression And Sensory Pathway Alterations | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,899,677 | May 1, 2013 | July 31, 2029 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Peripheral blood mononuclear cell epigenetic associations in and biomarkers for knee osteoarthritis development and progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,596,032 | June 16, 2020 | August 31, 2028 | JEFFRIES, MATLOCK | reporter.nih.gov |
| Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal Biomechanics | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,536,892 | July 14, 2016 | June 30, 2027 | MAJUMDAR, SHARMILA | reporter.nih.gov |
| Biomechanical and Biological Predictors of Cartilage Health Following Meniscus Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,493,420 | April 5, 2021 | March 31, 2026 | MCNULTY, AMY L | reporter.nih.gov |
| Studies on gut microbiome-joint connections in arthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,412,637 | April 1, 2021 | February 28, 2027 | ZUSCIK, MICHAEL J | reporter.nih.gov |
| BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL Reconstruction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $3,403,884 | August 1, 2018 | July 31, 2025 | SPINDLER, KURT PAUL | reporter.nih.gov |
| Innovative modeling of the biopsychosocial model in animals: Validation of outcomes for assessing emotional and cognitive domains affected by naturally-occurring chronic pain in dogs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $3,320,159 | September 18, 2024 | August 31, 2027 | GRUEN, MARGARET ELIZABETH | reporter.nih.gov |
| Wnt7a-Mediated Competence to Resist Osteoarthritis Progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,282,434 | February 15, 2021 | January 31, 2027 | ZENG, LI | reporter.nih.gov |
| Psychometric Reliability and Validity for Behavioral Metrics of Osteoarthritic Pain in Horses | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $3,196,061 | September 19, 2024 | August 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRI | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $3,194,922 | July 16, 2019 | June 30, 2025 | LI, XIAOJUAN | reporter.nih.gov |
| Is the gut important in multiple joint osteoarthritis? A multimodal investigation in humans and pet dogs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $3,176,745 | August 5, 2022 | June 30, 2027 | NELSON, AMANDA E | reporter.nih.gov |
| Multiparametric Mapping of Knee Joint with Magnetic Resonance Fingerprinting | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,138,468 | February 1, 2021 | August 31, 2027 | REGATTE, RAVINDER | reporter.nih.gov |
| Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $3,098,703 | August 12, 2022 | June 30, 2027 | KWOH, C KENT | reporter.nih.gov |
| Designing Novel MR Imaging Tools to Quantify Lower-Limb Exercise Adaptations in Knee Osteoarthritis | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2025 | $2,997,092 | September 20, 2003 | April 30, 2028 | GOLD, GARRY E | reporter.nih.gov |
| Metabolic Regulation of Articular Cartilage and Joint Homeostasis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,949,056 | July 8, 2021 | June 30, 2027 | O'KEEFE, REGIS J | reporter.nih.gov |
| Optimizing the value of pain management in knee OA patients with comorbidities | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,947,711 | August 1, 2018 | March 31, 2029 | LOSINA, ELENA | reporter.nih.gov |
| Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,931,322 | May 1, 2020 | April 30, 2027 | LI, XIAOJUAN | reporter.nih.gov |
| Molecular Pathways of Pain Generation in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,896,087 | February 1, 2011 | June 30, 2026 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Cannabinoid interactions with central and peripheral pain mechanisms in osteoarthritis of the knee | NIH | National Center for Complementary & Integrative Health | 2021 to 2024 | $2,864,374 | August 1, 2020 | May 31, 2026 | HARTE, STEVEN EDWARD | reporter.nih.gov |
| Simultaneous Imaging of Tissue Biochemistry and Metabolism associated with Biomechanics in Patella Femoral Joint Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,778,600 | March 15, 2022 | February 28, 2027 | SOUZA, RICHARD BRIAN | reporter.nih.gov |
| NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,777,000 | June 1, 2023 | November 30, 2025 | KARIN, MICHAEL | reporter.nih.gov |
| Understanding the mechanisms by which weight change affects progression of knee osteoarthritis in obese and overweight individuals: An analysis of the Osteoarthritis Initiative Dataset | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,775,126 | April 1, 2021 | October 31, 2026 | LINK, THOMAS M | reporter.nih.gov |
| FoxO transcription factors in joint aging and osteoarthritis pathogenesis | NIH | National Institute on Aging | 2021 to 2025 | $2,771,759 | May 15, 2018 | May 31, 2028 | LOTZ, MARTIN K | reporter.nih.gov |
| The Role of Creb5 in Maintaining Synovial Joint Homeostasis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,724,113 | July 28, 2022 | May 31, 2027 | LASSAR, ANDREW BRUCE | reporter.nih.gov |
| Establishing a Single-Cell Proteomic Atlas for Normal and Osteoarthritic Articular Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,626,425 | May 17, 2021 | March 31, 2026 | BHUTANI, NIDHI | reporter.nih.gov |
| Image-guided, robot-assisted reduction of joint dislocation in orthopaedic surgery | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,590,549 | September 1, 2021 | May 31, 2026 | UNERI, ALI | reporter.nih.gov |
| Rapid Low-Cost Quantitative 3D MRI and Gait Assessment of the Knee | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,579,635 | August 15, 2020 | June 30, 2025 | HARGREAVES, BRIAN ANDREW | reporter.nih.gov |
| Bioinspired Mechanically Stiff Hydrogels for Osteochondral Tissue Regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,563,338 | July 25, 2016 | March 31, 2027 | BRYANT, STEPHANIE J | reporter.nih.gov |
| The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,563,053 | August 1, 2020 | July 31, 2025 | HUARD, JOHNNY | reporter.nih.gov |
| A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III) | NIH | National Institute on Aging | 2024 to 2025 | $2,500,587 | September 15, 2024 | August 31, 2029 | FANNING, JASON | reporter.nih.gov |
| Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive Enzyme | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,493,979 | April 1, 2022 | March 31, 2027 | ALLEN, KYLE D | reporter.nih.gov |
| Integrative Omics analysis of human cartilage in aging and osteoarthritis | NIH | National Institute on Aging | 2021 to 2024 | $2,482,844 | January 15, 2016 | May 31, 2026 | LOTZ, MARTIN K | reporter.nih.gov |
| Deciphering multi-scale differentiation and patterning cues driving whole craniofacial joint regeneration | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,462,001 | September 6, 2022 | August 31, 2027 | SMEETON, JOANNA MARJORIE | reporter.nih.gov |
| Rapid Quantitative Assessment of Knee Joint with Compressed Sensing | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,428,622 | August 3, 2020 | July 31, 2026 | REGATTE, RAVINDER | reporter.nih.gov |
| CaMKK2 Signaling in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,408,999 | March 13, 2020 | January 31, 2026 | SANKAR, UMA | reporter.nih.gov |
| The Effects of Visit Characteristics on Patient-Clinician Interactions and Health Outcomes in Knee Osteoarthritis | NIH | National Institute on Aging | 2023 to 2025 | $2,402,726 | September 1, 2023 | June 30, 2028 | DOSSETT, MICHELLE L | reporter.nih.gov |
| OpenSim Enhancements to Enable Computational Design of Personalized Treatments for Movement Impairments | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,391,188 | September 6, 2021 | May 31, 2026 | FREGLY, BENJAMIN J | reporter.nih.gov |
| Demographic Distribution of Hand Joint Space | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $2,373,086 | September 27, 2021 | August 31, 2024 | KWOH, C KENT | reporter.nih.gov |
| Deconstructing Cartilage Mechanotransduction by Piezo Channels | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,369,902 | June 2, 2021 | July 31, 2025 | GUILAK, FARSHID | reporter.nih.gov |
| Enhancing modulation Effect of Baduanjin through Non-invasive Neuromodulation for knee Osteoarthritis | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $2,363,880 | August 4, 2023 | May 31, 2028 | KONG, JIAN | reporter.nih.gov |
| Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain (DIRECTPain) | NIH | National Institute of Nursing Research | 2022 to 2025 | $2,358,097 | September 21, 2022 | June 30, 2027 | SORGE, ROBERT | reporter.nih.gov |
| Imaging of Joint Response to Physiological Stress with Age, Sex and in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,351,319 | May 1, 2022 | February 28, 2027 | KOGAN, FELIKS | reporter.nih.gov |
| Identification of key regulators in rheumatoid arthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,309,449 | August 1, 2014 | April 30, 2026 | WANG, WEI | reporter.nih.gov |
| Joint Pain on a Chip: Mechanistic Analysis Therapeutic Targets and an Empirical Strategy for Personalized Pain Management | NIH | National Center for Advancing Translational Sciences | 2021 | $2,287,391 | September 26, 2019 | July 31, 2025 | GOLD, MICHAEL S | reporter.nih.gov |
| Move and Snooze: Adding insomnia treatment to an exercise program to improve pain outcomes in older adults with knee osteoarthritis | NIH | National Institute on Aging | 2023 to 2025 | $2,261,590 | September 30, 2023 | June 30, 2028 | WHIBLEY, DANIEL | reporter.nih.gov |
| Cell Senescence Regulating Osteoarthritis Progression: Sex-dependent Mechanisms | NIH | National Institute on Aging | 2023 to 2025 | $2,244,684 | January 15, 2023 | November 30, 2027 | CHEN, QIAN | reporter.nih.gov |
| Arthroscopic Raman Monitoring of Cartilage Content for PTOA Diagnosis and Chondroregenerative Treatment Response | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,239,693 | August 2, 2022 | May 31, 2027 | ALBRO, MICHAEL B | reporter.nih.gov |
| Roles of Collagen and Water in the Fracture Resistance of Bone | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,220,473 | September 1, 2012 | May 31, 2027 | NYMAN, JEFFRY STEPHEN | reporter.nih.gov |
| Interpretation and Utility of Novel Composite Structural Endpoints of Cumulative Damage and Disease Activity in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,206,921 | January 23, 2024 | May 31, 2026 | DRIBAN, JEFFREY B | reporter.nih.gov |
| Promoting regenerative repair of aged cartilage | NIH | National Institute on Aging | 2023 to 2025 | $2,189,662 | May 15, 2023 | January 31, 2028 | COLLINS, JOHN A | reporter.nih.gov |
| Modification of Post-Traumatic Osteoarthritis Progression with Joint Unloading | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $2,182,992 | March 1, 2020 | November 30, 2025 | CHRISTIANSEN, BLAINE A. | reporter.nih.gov |
| Digital Biomarkers of Post-traumatic Osteoarthritis: Toward Precision Rehabilitation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,179,833 | September 1, 2022 | August 31, 2027 | HALILAJ, ENI | reporter.nih.gov |
| Probing Osteoarthritis Pathogenesis by Noninvasive Imaging of Cartilage Strain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $2,176,180 | September 19, 2013 | March 31, 2025 | NEU, COREY P | reporter.nih.gov |
| Tissue Adhesive RNA Interference Nanoparticles to Block Progression of Posttraumatic and Spontaneous Osteoarthritis. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,136,077 | August 22, 2022 | July 31, 2027 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Improvement of Animal Models for TMJ Stem Cell-Based Regeneration | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2023 | $2,135,816 | July 15, 2019 | April 30, 2025 | EMBREE, MILDRED CHRISTINE | reporter.nih.gov |
| A Bio-inspired Latent TGF-beta Conjugated Scaffold for Patient-specific Cartilage Regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,133,303 | June 1, 2022 | May 31, 2027 | ALBRO, MICHAEL B | reporter.nih.gov |
| Data-Driven Learning Framework for Fast Quantitative Knee Joint Mapping | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,115,033 | July 1, 2021 | May 31, 2027 | WUST ZIBETTI, MARCELO VICTOR | reporter.nih.gov |
| Neural immunoregulation of post-traumatic autoimmunity | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,111,177 | September 1, 2016 | July 31, 2027 | KINGERY, WADE S | reporter.nih.gov |
| Intra-cartilage depot delivery of electrically-charged IL-1RA for targeting osteoarthritis-associated inflammation and catabolism in multiple joint tissues | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,062,254 | September 21, 2020 | July 31, 2026 | BAJPAYEE, AMBIKA GOEL | reporter.nih.gov |
| Multinuclear MRI to Assess Joint Homeostasis after Knee Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,048,056 | July 1, 2022 | November 30, 2027 | MADELIN, GUILLAUME | reporter.nih.gov |
| Brain Pathophysiology of Osteoarthritis Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $2,046,367 | February 1, 2019 | December 31, 2024 | APKARIAN, APKAR VANIA | reporter.nih.gov |
| Neural Ice Technology for Treatment of Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $2,045,816 | August 21, 2024 | July 31, 2027 | SIDOTI, CHARLES | reporter.nih.gov |
| Subchondral Trabecular Plate and Rod Abnormalities in Human Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,030,282 | June 1, 2023 | May 31, 2028 | GUO, X. EDWARD | reporter.nih.gov |
| Genomic and Imaging Markers to Understand and Predict Progression of Joint Damage After Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,029,292 | August 8, 2023 | July 31, 2028 | KIRSCH, THORSTEN | reporter.nih.gov |
| Sustained Biomaterial-mediated Inhibition of R-spondin 2 to Target Pathological Wnt Signaling in Post-Traumatic Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,029,238 | September 15, 2022 | June 30, 2027 | HANKENSON, KURT DAVID | reporter.nih.gov |
| Age-related decline in endogenous pain modulation and its impact on osteoarthritis pain | NIH | National Institute on Aging | 2022 to 2025 | $2,028,372 | June 1, 2022 | March 31, 2027 | RO, JIN Y | reporter.nih.gov |
| Brain-based and clinical phenotyping of pain pharmacotherapy in knee OA | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,020,563 | August 15, 2023 | July 31, 2028 | SCHNITZER, THOMAS JACK | reporter.nih.gov |
| Intra-articular corticosteroid injections for symptomatic osteoarthritis: The effects of injection dose, frequency, and timing on safety | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $2,017,972 | September 10, 2025 | August 31, 2028 | BUTLER, ANNE MOBLEY | reporter.nih.gov |
| Revision ACL Reconstruction: A Comparative Effectiveness Treatment Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,009,015 | September 1, 2011 | August 30, 2029 | WRIGHT, RICK W | reporter.nih.gov |
| Elucidation of the Role of Creb5 in Synovial Joint Formation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $2,004,843 | September 18, 2019 | May 9, 2025 | LASSAR, ANDREW BRUCE | reporter.nih.gov |
| Augmented Reality Platform for Telehealth Rehabilitation | NIH | National Institute on Aging | 2023 to 2025 | $1,998,221 | June 1, 2021 | October 31, 2026 | SHIWANI, BHAWNA | reporter.nih.gov |
| The Study of Muscle, Mobility and Aging with Knee OA | NIH | National Institute on Aging | 2021 to 2025 | $1,995,873 | September 1, 2021 | May 31, 2027 | LANE, NANCY E | reporter.nih.gov |
| The Role of Mechanosensation Pathways in Osteoarthritis Joint Damage and Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,990,517 | April 2, 2021 | August 31, 2026 | MILLER, RACHEL ELIZABETH | reporter.nih.gov |
| Evaluation of mechanistic role of artemin/GFRα3 signaling in osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $1,988,920 | May 1, 2022 | April 30, 2028 | MISHRA, SANTOSH K. | reporter.nih.gov |
| Identifying novel osteoarthritis risk genes using GWAS, chondrocyte genomics, and genome editing | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,950,418 | September 20, 2022 | August 31, 2027 | PHANSTIEL, DOUGLAS H. | reporter.nih.gov |
| Cellular Stress in Pain and Tissue Damage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $1,950,412 | September 10, 2025 | August 31, 2028 | ROMERO-SANDOVAL, E. ALFONSO | reporter.nih.gov |
| Phlpp phosphatases in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,935,825 | September 21, 2022 | August 31, 2027 | WESTENDORF, JENNIFER J | reporter.nih.gov |
| Role of DNA damage and cellular senescence in osteoarthritis pathophysiology | NIH | National Institute on Aging | 2023 to 2025 | $1,923,686 | September 30, 2023 | May 31, 2028 | DIEKMAN, BRIAN O | reporter.nih.gov |
| In Vivo Knee Motion and ACL Biomechanics During Dynamic Activities | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,913,305 | May 1, 2014 | July 31, 2025 | DEFRATE, LOUIS E. | reporter.nih.gov |
| A self-assembled hydrogel with tunable drug release kinetics for preventing osteoarthritis in active joints | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,875,630 | May 1, 2021 | March 31, 2027 | JOSHI, NITIN | reporter.nih.gov |
| Cartilage Regeneration with Tunable Inflammation Resistance | NIH | National Institute on Aging | 2021 to 2023 | $1,862,105 | September 15, 2017 | May 31, 2026 | ESTES, BRADLEY T | reporter.nih.gov |
| PARTIAL MENISCECTOMY VS. NONOPERATIVE MGMT. IN MENISCAL TEAR WITH OA: AN RCT | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,851,873 | September 21, 2007 | August 31, 2025 | KATZ, JEFFREY NEIL | reporter.nih.gov |
| Nonaddictive opioid prodrug nanomedicine for musculoskeletal pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,851,532 | September 7, 2022 | July 31, 2027 | WANG, DONG | reporter.nih.gov |
| Knee-Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT) | NIH | National Institute on Aging | 2023 to 2024 | $1,836,814 | September 30, 2018 | November 30, 2025 | KREPKOVICH, EILEEN T. | reporter.nih.gov |
| STABILITY 2: ACL Reconstruction +/- Lateral Tenodesis with Patellar vs. Quad Tendon | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,826,074 | September 17, 2019 | February 28, 2026 | IRRGANG, JAMES JOHN | reporter.nih.gov |
| Translational strategies for optimizing musculoskeletal recovery after ACL injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,813,356 | August 15, 2022 | May 31, 2027 | LEPLEY, LINDSEY K | reporter.nih.gov |
| Collagen-mediated approaches to improve the local delivery and hypothermic release of osteoarthritis therapeutics | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,801,687 | September 1, 2023 | July 31, 2028 | KIICK, KRISTI L | reporter.nih.gov |
| EGFR signaling in osteoarthritis and treatment | NIH | National Institute on Aging | 2021 to 2024 | $1,794,940 | September 30, 2020 | June 30, 2025 | QIN, LING | reporter.nih.gov |
| Morphological and Biomechanical Insights into the Pathophysiology of Femoroacetabular Impingement Syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,794,039 | July 1, 2020 | June 30, 2027 | ANDERSON, ANDREW EDWARD | reporter.nih.gov |
| Endogenous retrovirus in joint aging and osteoarthritis development | NIH | National Institute on Aging | 2023 to 2025 | $1,791,833 | August 15, 2023 | April 30, 2028 | YANG, TAO | reporter.nih.gov |
| Regulation of chondrocyte fate and function by ECM Viscoelasticity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,772,780 | September 1, 2023 | June 30, 2028 | BHUTANI, NIDHI | reporter.nih.gov |
| Carpometacarpal Osteoarthritis: Understanding the Intersection of Muscle Mechanics, Joint Instability, and Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,766,845 | April 1, 2022 | March 31, 2027 | NICHOLS, JENNIFER A. | reporter.nih.gov |
| A Multisystem Resilience Approach in the Assessment of Postsurgical Pain Trajectories | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,766,506 | September 14, 2023 | July 31, 2028 | BARTLEY, EMILY J. | reporter.nih.gov |
| Effect of statin intake on Non-traumatic Generalized Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,765,770 | September 22, 2021 | August 31, 2026 | DEMEHRI, SHADPOUR | reporter.nih.gov |
| Molecular engineering of HA-based lubricants for articular cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,761,424 | July 21, 2023 | June 30, 2028 | VARGHESE, SHYNI | reporter.nih.gov |
| Multi-Scale In Vitro 3D Tissue Model of Vascularized Bone-Cartilage Interactions | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,730,750 | September 21, 2017 | August 31, 2024 | ROEHM, KEVIN | reporter.nih.gov |
| MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,730,414 | September 1, 2018 | December 31, 2024 | PALMIERI-SMITH, RIANN MARIE | reporter.nih.gov |
| Treating knee osteoarthritis by sPLA2 inhibitor-loaded micellar nanoparticles | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,715,893 | April 1, 2022 | March 31, 2028 | CHENG, ZHILIANG | reporter.nih.gov |
| Preoperative perturbation training to prevent falls after total knee arthroplasty | NIH | National Institute on Aging | 2022 to 2024 | $1,709,303 | September 1, 2022 | June 30, 2027 | FOUCHER, KHARMA CHARISSE | reporter.nih.gov |
| Quantitative bone radiomics using Ultra-High Resolution CT | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $1,691,144 | July 1, 2021 | March 31, 2026 | ZBIJEWSKI, WOJCIECH BARTOSZ | reporter.nih.gov |
| ProGel Technology for Better Management of Osteoarthritis Pain | NIH | National Institute on Drug Abuse | 2021 to 2022 | $1,680,880 | May 1, 2020 | December 31, 2023 | GOLDRING, STEVEN | reporter.nih.gov |
| Randomized controlled trial evaluating an innovative community-based intervention combining group-based exercise and behavioral health skills-training for older adults with painful knee osteoarthritis | NIH | National Institute on Aging | 2021 to 2023 | $1,676,006 | May 1, 2019 | April 30, 2025 | PATEL, KUSHANG | reporter.nih.gov |
| Articular Cartilage Tissue Engineering with Human Pluripotent Stem Cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,673,298 | April 1, 2021 | March 31, 2027 | NAKAYAMA, NAOKI | reporter.nih.gov |
| Treatment and prevention of osteoarthritis with an intra-articular disease-modifying regenerative therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,671,789 | September 16, 2021 | August 31, 2024 | ANGLE, SIDDHESH | reporter.nih.gov |
| Cell-Matrix Regulation of Fibrochondrocytes in TMJ OA | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $1,659,762 | April 1, 2021 | March 31, 2026 | REED, DAVID ANDREW | reporter.nih.gov |
| Rapid Three-dimensional Simultaneous Knee Multi-Relaxation Mapping | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,652,212 | July 15, 2022 | May 31, 2027 | LIU, FANG | reporter.nih.gov |
| Biodegradable Piezoelectric Nanocomposite Scaffold with Physical Exercise to Heal Major Cartilage Defects in Large Animals | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,650,011 | June 3, 2022 | April 30, 2027 | NGUYEN, THANH | reporter.nih.gov |
| Assessment of ultrasound features of knee osteoarthritis in a population-based community cohort | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,642,059 | May 5, 2020 | April 30, 2025 | NELSON, AMANDA E | reporter.nih.gov |
| ROS scavenging nanoparticles for mitigating oxidative stress in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,641,378 | February 23, 2023 | January 31, 2029 | SHARMA, BLANKA | reporter.nih.gov |
| Modulation of Inflammation in Osteoarthritis via CD14-mediated pattern recognition | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,640,656 | August 1, 2020 | July 31, 2026 | SCANZELLO, CARLA ROSE | reporter.nih.gov |
| Oxidative Stress and the Development of Osteoarthritis | NIH | National Institute on Aging | 2021 to 2025 | $1,625,347 | September 30, 2012 | February 29, 2028 | LOESER, RICHARD F | reporter.nih.gov |
| Advanced 7 Tesla imaging of the knee for root cause of Osteoarthritis | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $1,623,129 | August 1, 2023 | July 31, 2027 | ELLERMANN, JUTTA M | reporter.nih.gov |
| Development of Injectable Super-Lubricious Microgels for Sustained Release of Platelet-Rich Plasma to Treat Post-Traumatic Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,619,642 | May 10, 2023 | March 31, 2028 | ZUSTIAK, SILVIYA PETROVA | reporter.nih.gov |
| Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis | NIH | National Institute on Aging | 2024 to 2025 | $1,614,347 | September 25, 2024 | May 31, 2027 | VALERO, ERIKA | reporter.nih.gov |
| Patient-centered Development of a Composite Digital Endpoint of Mobility and Pain for Knee Osteoarthritis | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,614,289 | August 1, 2025 | July 31, 2027 | KUMAR, DEEPAK | reporter.nih.gov |
| Central Sensitization and Sleep Disturbance as Predictors of Treatment Outcomes in Patients with Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,605,759 | August 1, 2021 | July 31, 2026 | CAMPBELL, CLAUDIA MICHELLE | reporter.nih.gov |
| Role of Glucose metabolism in Chondrocyte Mechanotransduction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,576,819 | June 1, 2019 | February 28, 2026 | JUNE, RONALD KENT | reporter.nih.gov |
| Regenerative Rehabilitative Principles in Modulating Weight Bearing and Joint Kinematics to Delay Post-Traumatic Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,576,611 | April 1, 2022 | January 31, 2027 | TSAI, LIANG-CHING | reporter.nih.gov |
| Morphologic and Kinematic Adaptations of the Subtalar Joint after Ankle Fusion Surgery in Patients with Varus-type Ankle Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,557,053 | September 12, 2023 | August 31, 2028 | ANDERSON, ANDREW EDWARD | reporter.nih.gov |
| Synovial lymphatics and osteoarthritis in aging | NIH | National Institute on Aging | 2021 to 2024 | $1,542,007 | January 1, 2020 | November 30, 2025 | XING, LIANPING | reporter.nih.gov |
| Disease Modifying Analgesia with CA8 Gene Therapy | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $1,516,241 | September 30, 2021 | September 15, 2023 | LEVITT, ROY C. | reporter.nih.gov |
| Develop BCL-xL proteolysis targeting chimeras as safer and better senolytics | NIH | National Institute on Aging | 2021 to 2023 | $1,510,674 | August 1, 2019 | March 31, 2025 | ZHENG, GUANGRONG | reporter.nih.gov |
| Role of Desumoylase SENP6 in Joint Aging and Osteoarthritis Development | NIH | National Institute on Aging | 2021 to 2023 | $1,495,470 | July 15, 2019 | September 30, 2025 | YANG, TAO | reporter.nih.gov |
| Growth hormone regulating chondrocyte metabolism for osteoarthritis development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,486,776 | July 3, 2023 | May 31, 2028 | ZHU, SHOUAN | reporter.nih.gov |
| Unraveling Fundamental Mechanisms of Interorgan Crosstalk in Osteoarthritis | NIH | National Institute on Aging | 2024 | $1,476,001 | September 15, 2024 | August 31, 2027 | COLLINS, KELSEY HELEN-MARIE | reporter.nih.gov |
| Deep Learning-based Imaging Biomarkers for Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,471,178 | July 2, 2019 | October 31, 2024 | DENIZ, CEM MURAT | reporter.nih.gov |
| Activation of endogenous progenitors via a nanoparticle-conjugated fibrous system to enhance meniscus repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,467,367 | February 20, 2023 | November 30, 2027 | QIN, LING | reporter.nih.gov |
| Imaging and therapeutic targeting of tissue crosstalk in the injured knee | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,454,755 | March 15, 2024 | February 28, 2029 | RUIZ GARZON, MARIA AMPARO | reporter.nih.gov |
| Synthetic Cartilage-Capped, Regenerative Osteochondral Plugs to Heal Osteochondral Defects | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,449,070 | January 1, 2024 | December 31, 2025 | GRUNLAN, MELISSA | reporter.nih.gov |
| Cannabis Use Impact on Pain and Recovery Post-Surgery - The Role of the Endocannabinoid System | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,443,561 | September 5, 2025 | August 31, 2030 | INGRAM, SUSAN L | reporter.nih.gov |
| Integrative Predictors of Temporomandibular Degenerative Joint Disease | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $1,439,575 | September 10, 2013 | January 30, 2026 | CEVIDANES, LUCIA H | reporter.nih.gov |
| The Role of Sodium Channel Nav1.7 in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,434,901 | March 18, 2024 | August 31, 2028 | LIU, CHUANJU | reporter.nih.gov |
| Adding Bright Light Treatment to Cognitive-Behavioral Therapy for Insomnia to Prevent Chronic Post-Surgical Pain in Older Adults | NIH | National Institute on Aging | 2024 to 2025 | $1,415,293 | August 1, 2024 | July 31, 2029 | SMITH, MICHAEL T | reporter.nih.gov |
| Development of Sodium Fluoride PET-MRI for Quantitative Assessment of Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,369,656 | August 16, 2019 | June 30, 2025 | GOLD, GARRY E | reporter.nih.gov |
| Defining the unique capacity of the miniature joint model for investigating the role of adipose tissue and its impacts on osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,365,070 | May 15, 2024 | April 30, 2029 | LIN, HANG | reporter.nih.gov |
| Metabolomic Profiling to Identify Candidate Biomarker Profiles and Molecular Endotypes for Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,362,647 | August 10, 2023 | July 31, 2028 | JUNE, RONALD KENT | reporter.nih.gov |
| Interpretation and Utility of Novel Composite Structural Endpoints of Cumulative Damage and Disease Activity in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,355,310 | June 1, 2021 | June 30, 2023 | DRIBAN, JEFFREY B | reporter.nih.gov |
| Targeting the PTH1R Signaling Pathway for Osteoarthritis Therapy by a Novel Disruptor Peptide | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,348,776 | August 1, 2020 | July 31, 2025 | WANG, BIN | reporter.nih.gov |
| Preclinical assessment of a novel systemic drug candidate for osteoarthritic pain | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $1,348,453 | June 1, 2023 | May 31, 2025 | EVSEENKO, DENIS | reporter.nih.gov |
| Chondrocyte DNA Double-Strand Breaks in the Pathogenesis of Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,331,484 | May 7, 2020 | April 30, 2025 | JONASON, JENNIFER HARRELL | reporter.nih.gov |
| Clinical Interpretation of PROMs in Care of Knee Osteoarthritis and TJR | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,331,338 | July 16, 2024 | April 30, 2028 | FRANKLIN, PATRICIA D | reporter.nih.gov |
| Biomechanics of Cartilage: Roles of Decorin in ECM Assembly and Degradation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,326,261 | August 1, 2019 | December 31, 2025 | HAN, LIN | reporter.nih.gov |
| Cellular Senescence Network: New Imaging Tools for Arthritis Imaging | NIH | National Cancer Institute | 2023 to 2024 | $1,289,471 | September 23, 2021 | August 31, 2025 | DALDRUP-LINK, HEIKE ELIZABETH | reporter.nih.gov |
| Mechanism of Tgfbr2 in Chondroprotection | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,283,931 | April 1, 2013 | March 31, 2026 | SERRA, ROSA A. | reporter.nih.gov |
| Lipid Metabolism in Articular Cartilage and OA Pathogenesis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,283,775 | June 12, 2024 | May 31, 2029 | SHEN, JIE | reporter.nih.gov |
| How Partial Meniscectomy Affects Contact Mechanics and Tissue Response | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,275,050 | August 12, 2019 | April 30, 2025 | MAHER, SUZANNE A. | reporter.nih.gov |
| Mechanotransduction in Meniscus Health and Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,257,415 | January 15, 2019 | December 31, 2024 | MCNULTY, AMY L | reporter.nih.gov |
| Cbf mediates articular cartilage regeneration and repair in aging | NIH | National Institute on Aging | 2021 to 2023 | $1,250,727 | August 1, 2019 | April 30, 2026 | CHEN, WEI | reporter.nih.gov |
| Role of CCR2 in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,245,594 | August 1, 2017 | May 31, 2029 | LONGOBARDI, LARA | reporter.nih.gov |
| Bioactive Injectable Cell Scaffold for Meniscus Injury Repair in a Large Animal Model | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,244,807 | September 4, 2023 | August 31, 2028 | JAYASURIYA, CHATHURAKA TEEKSHANA | reporter.nih.gov |
| Brain Mechanisms of Chronic Low-Back Pain: Specificity and Effects of Aging and Sex | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,214,654 | April 1, 2023 | March 31, 2028 | GEHA, PAUL | reporter.nih.gov |
| WNT signaling in chondrocyte biology and osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,208,493 | September 1, 2024 | August 31, 2029 | WU, CHIA-LUNG | reporter.nih.gov |
| GP130/STAT3 signalling in articular cartilage development and regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,208,109 | April 1, 2018 | January 31, 2024 | EVSEENKO, DENIS | reporter.nih.gov |
| Epigenetic Regulation in Cartilage Tissue | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,207,511 | March 1, 2016 | March 31, 2029 | O'KEEFE, REGIS J | reporter.nih.gov |
| Uncovering the Genetic Mechanisms Behind Joint-Specific Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,202,184 | April 1, 2018 | January 31, 2024 | CAPELLINI, TERENCE D | reporter.nih.gov |
| Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $1,199,996 | September 8, 2015 | July 31, 2025 | ESTES, BRADLEY T | reporter.nih.gov |
| Roles of Type III Collagen in the Matrix Assembly and Mechanobiology of Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,194,196 | May 10, 2024 | April 30, 2029 | HAN, LIN | reporter.nih.gov |
| The adaptive response of skeletal muscle, bone, and cartilage to severe knee trauma involving ACL disruption with and without concomitant injury to the meniscus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,193,778 | July 1, 2020 | June 30, 2025 | BEYNNON, BRUCE | reporter.nih.gov |
| Modulating PTOA development with parathyroid hormone | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,187,907 | September 15, 2023 | August 31, 2028 | VAN DER MEULEN, MARJOLEIN C | reporter.nih.gov |
| Individual cell bioprinting to generate multi-tissue type condensations for osteochondral tissue regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,186,717 | April 5, 2023 | February 29, 2028 | ALSBERG, EBEN | reporter.nih.gov |
| Depositing Data Generated from Drug Test on microJoint Model into the Microphysiology Systems Database | NIH | National Center for Advancing Translational Sciences | 2021 | $1,186,687 | August 20, 2017 | June 30, 2023 | LIN, HANG | reporter.nih.gov |
| Longitudinal Biomechanics and Patient-Reported Outcomes after Periacetabular Osteotomy for Developmental Dysplasia of the Hip | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $1,172,323 | February 10, 2023 | December 31, 2025 | HARRIS, MICHAEL D | reporter.nih.gov |
| Contribution of the NOD/RIPK2 signaling pathway to osteoarthritis susceptibility | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,169,691 | April 1, 2024 | March 31, 2029 | JURYNEC, MICHAEL J | reporter.nih.gov |
| Mapping temporomandibular joint (TMJ) degeneration and pain | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $1,161,054 | July 1, 2024 | April 30, 2029 | CHEN, JIANFU | reporter.nih.gov |
| Prevention of PTOA via regulation of the cytomechanics of chondrocytes | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,160,687 | September 1, 2020 | July 31, 2026 | LU, X. LUCAS | reporter.nih.gov |
| A Novel Glycosaminoglycan Mimetic Scaffold for Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,152,862 | March 16, 2021 | February 28, 2027 | ARINZEH, TREENA LYNNE | reporter.nih.gov |
| Roles of SOX8 and SOX9 in Adult Articular Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,149,371 | July 8, 2018 | June 30, 2024 | LEFEBVRE, VERONIQUE M | reporter.nih.gov |
| Disc-Facet Crosstalk During Spinal Degeneration and Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,143,510 | September 26, 2024 | August 31, 2029 | GULLBRAND, SARAH E | reporter.nih.gov |
| Sex Dimorphism in Age-Related Knee Osteoarthritis | NIH | National Institute on Aging | 2024 to 2025 | $1,132,326 | September 15, 2024 | May 31, 2028 | AMBROSIO, FABRISIA | reporter.nih.gov |
| OA Pathogenesis beyond Cartilage: A preclinical study of the sources of OA pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,130,706 | March 1, 2018 | February 29, 2024 | ALLEN, KYLE D | reporter.nih.gov |
| The role of vascular failure and biomechanical stress in the development, progression and healing of osteochondritis dissecans lesions | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,129,716 | August 9, 2024 | May 31, 2029 | TOTH, FERENC | reporter.nih.gov |
| Carrier Free siRNA Conjugates as Disease Modifying Osteoarthritis Drugs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,122,583 | September 10, 2024 | July 31, 2029 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Disease Modifying Analgesia with CA8 Gene Therapy | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $1,109,446 | September 16, 2023 | September 30, 2026 | LEVITT, ROY C. | reporter.nih.gov |
| Treatment of Meniscal Problems in Osteoarthritis: TeMPO | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,093,180 | April 15, 2017 | March 31, 2023 | KATZ, JEFFREY NEIL | reporter.nih.gov |
| Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,089,490 | September 1, 2020 | August 31, 2025 | LEDOUX, WILLIAM R. | reporter.nih.gov |
| Genetics of Osteoarthritis Susceptibility, Heterogeneity and Progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,087,578 | August 22, 2024 | July 31, 2029 | MCDONALD DONNELLY, MERRY-LYNN NOELLE | reporter.nih.gov |
| Repurposing FDA-approved drugs for the treatment of osteoarthritis using high-throughput screening in microphysiological models | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,085,742 | August 15, 2024 | July 31, 2029 | LIN, HANG | reporter.nih.gov |
| Environmental Factors Associated with the Development of Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,081,730 | February 1, 2024 | January 31, 2027 | DRIBAN, JEFFREY B | reporter.nih.gov |
| The Role of MicroRNA in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $1,069,484 | August 1, 2017 | October 31, 2024 | HUANG, JIAN | reporter.nih.gov |
| Cellular Senescence Network: New Imaging Tools for Arthritis Imaging | NIH | National Cancer Institute | 2021 to 2022 | $1,059,697 | September 23, 2021 | August 31, 2023 | DALDRUP-LINK, HEIKE ELIZABETH | reporter.nih.gov |
| Device Automation of an FDA-cleared CD-Microfluidic Platform for Rapid Tissue Microsizing | NIH | National Center for Advancing Translational Sciences | 2025 | $1,050,276 | September 25, 2025 | August 31, 2027 | ZOBI, AHMED NABIL | reporter.nih.gov |
| Weight loss, in vivo cartilage mechanics, and joint health | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,048,432 | January 15, 2019 | December 31, 2025 | DEFRATE, LOUIS E. | reporter.nih.gov |
| Viscoelastic Properties of Normal and OA Chondrons | NIH | National Institute on Aging | 2021 to 2022 | $1,027,495 | January 1, 1998 | March 31, 2025 | GUILAK, FARSHID | reporter.nih.gov |
| Novel Non-Contrast MRI to Assess Synovitis in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $1,017,844 | April 19, 2024 | February 28, 2029 | KOGAN, FELIKS | reporter.nih.gov |
| Title: BMP/TGFbeta crosstalk in cartilage maintenance and osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,015,872 | July 19, 2018 | April 30, 2024 | LYONS, KAREN M. | reporter.nih.gov |
| Dissecting molecular mechanisms implicated in age- and osteoarthritis-related decline in anabolism in articular cartilage | NIH | National Institute on Aging | 2021 to 2023 | $1,014,750 | February 1, 2019 | November 30, 2024 | EVSEENKO, DENIS | reporter.nih.gov |
| Efficacy of MeniscoFix for Sub-Total Meniscal Replacement: A Comprehensive Approach in Cadaver Knees and an Ovine Surgical Model | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $1,013,912 | July 15, 2022 | June 30, 2027 | WEADOCK, KEVIN S | reporter.nih.gov |
| Therapeutic targeting of GPCR Gbetagamma-GRK2 in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $998,289 | February 21, 2019 | December 31, 2024 | KAMAL, FADIA ALI | reporter.nih.gov |
| Piezo1 and Piezo2-dependent cartilage health and disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $996,072 | April 1, 2023 | March 31, 2028 | LEE, WHASIL | reporter.nih.gov |
| Pain-related Brain Mechanisms for Pain Catastrophizing Behavior in Response to Home-based Mindfulness-based Meditation Paired with Transcranial Direct Current Stimulation | NIH | National Institute of Nursing Research | 2022 | $973,809 | September 1, 2022 | January 31, 2025 | AHN, HYOCHOL | reporter.nih.gov |
| Obesity, Biomechanics, and Inflammation in Osteoarthritis | NIH | National Institute on Aging | 2021 to 2023 | $968,625 | September 30, 2013 | April 30, 2025 | GUILAK, FARSHID | reporter.nih.gov |
| Combination Therapy of Home-based Trans-cranial Direct Current Stimulation and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms in Older Adults with Knee Osteoarthritis | NIH | National Institute of Nursing Research | 2023 to 2025 | $963,281 | April 14, 2020 | November 30, 2025 | AHN, HYOCHOL | reporter.nih.gov |
| Large-scale automatic analysis of the OAI magnetic resonance image dataset | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $929,619 | August 15, 2017 | April 30, 2024 | NIETHAMMER, MARC | reporter.nih.gov |
| Molecular Engineering of Cartilage PCM Mechanotransduction in Osteoarthritis Using Biomimetic Proteoglycans | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $927,833 | July 10, 2022 | June 30, 2027 | MARCOLONGO, MICHELE S | reporter.nih.gov |
| Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic Trial | NIH | National Center for Complementary & Integrative Health | 2023 | $911,699 | May 19, 2023 | August 31, 2024 | WANG, CHENCHEN | reporter.nih.gov |
| KLF4 in joint degradation and regeneration | NIH | National Institute on Aging | 2021 to 2022 | $907,736 | September 30, 2018 | May 31, 2025 | LOTZ, MARTIN K | reporter.nih.gov |
| Therapeutic role of NFAT1 Transcription Factor in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $900,405 | August 1, 2024 | July 31, 2029 | WANG, JINXI | reporter.nih.gov |
| Quantitative UTE MR Imaging: Sensitive Biomarkers for Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $887,284 | September 1, 2013 | February 29, 2024 | DU, JIANG | reporter.nih.gov |
| Prognostic Study of the Risk Factors for Contralateral ACL Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $861,401 | September 7, 2007 | August 31, 2025 | BEYNNON, BRUCE | reporter.nih.gov |
| A Treatment Paradigm for Femoracetabular Impingement (FAI) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $849,426 | June 1, 2020 | May 31, 2023 | ESTES, BRADLEY T | reporter.nih.gov |
| Systemic contribution of age-associated epigenetic mechanisms to osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $842,622 | September 9, 2019 | June 30, 2025 | YAU, MICHELLE SZU-HUEI | reporter.nih.gov |
| Mechanisms of Oxytocins Analgesia in Older Adults | NIH | National Institute on Aging | 2021 to 2022 | $828,868 | August 1, 2018 | April 30, 2024 | CRUZ-ALMEIDA, YENISEL | reporter.nih.gov |
| ACL Deficiency Modifies Topographical Degradation in Posttraumatic Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $824,998 | April 1, 2016 | March 31, 2025 | XIA, YANG | reporter.nih.gov |
| Long-term Outcomes of Knee OA in the OAI Cohort | NIH | National Institute on Aging | 2021 | $819,214 | September 15, 2017 | May 31, 2024 | NEVITT, MICHAEL C | reporter.nih.gov |
| Treatment and prevention of osteoarthritis with an intra-articular disease-modifying regenerative therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $797,793 | August 5, 2024 | July 31, 2026 | ANGLE, SIDDHESH | reporter.nih.gov |
| Engineered cells as agents of arthritis therapy governed by artificial signaling | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $788,242 | September 17, 2024 | July 31, 2029 | BRUNGER, JONATHAN MATTHEW | reporter.nih.gov |
| Risk Factors for End-Stage Glenohumeral Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $759,943 | September 18, 2024 | June 30, 2029 | ROWLANDS, ELIZABETH YANIK | reporter.nih.gov |
| Mentoring Biomechanics Research in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $755,810 | April 1, 2018 | June 30, 2029 | SOUZA, RICHARD BRIAN | reporter.nih.gov |
| Integrating brain and behavioral measures of central pain inhibition to personalize treatment in chronic pain management | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $748,927 | April 1, 2022 | February 28, 2027 | ALTER, BENEDICT J | reporter.nih.gov |
| The role of FGFR3 in the effects of PTH in the Mandibular Condyle | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $747,360 | April 1, 2020 | March 31, 2026 | DUTRA, ELIANE | reporter.nih.gov |
| Development of Drug Delivery Technology for Stem Cell Based TMJ Regeneration | NIH | National Institute of Dental & Craniofacial Research | 2021 | $742,838 | August 1, 2018 | January 31, 2024 | CHEN, MO | reporter.nih.gov |
| TMJ-on-a-chip for delineating multi-tissue crosstalk in inflammation and pathophysiological mechanical loadings | NIH | National Institute of Dental & Craniofacial Research | 2025 | $738,929 | August 1, 2025 | April 30, 2030 | LEE, CHANG HUN | reporter.nih.gov |
| Using redox balance to guide surgical and therapeutic decisions for cartilage disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $736,331 | September 1, 2024 | August 31, 2028 | HENAK, CORINNE R | reporter.nih.gov |
| Green Light Therapy and Brain Mechanisms of Pain and Anxiety | NIH | National Center for Complementary & Integrative Health | 2025 | $733,870 | September 12, 2025 | May 31, 2030 | DA SILVA, JOYCE TEIXEIRA | reporter.nih.gov |
| Simulation framework to develop ankle exoskeleton gait assistance for older adults | NIH | National Institute on Aging | 2022 to 2024 | $727,327 | April 1, 2020 | March 31, 2026 | SONG, SEUNGMOON | reporter.nih.gov |
| Mentoring in Patient Oriented Research in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $718,915 | August 25, 2022 | July 31, 2027 | NELSON, AMANDA E | reporter.nih.gov |
| Integrated Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $716,032 | September 13, 2018 | June 30, 2025 | LU, HELEN H | reporter.nih.gov |
| The Role of Fat in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $714,633 | August 1, 2023 | June 30, 2026 | COLLINS, KELSEY HELEN-MARIE | reporter.nih.gov |
| Intraganglionic Analgesic Adeno-Associated Virus (AAV) Gene Vector Optimization in Large Animals | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $709,984 | August 14, 2019 | July 31, 2023 | BEUTLER, ANDREAS S. | reporter.nih.gov |
| Simultaneous Imaging of Tissue Biochemistry and Metabolism associated with Biomechanics in Patella Femoral Joint Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $706,325 | September 22, 2021 | March 14, 2022 | PEDOIA, VALENTINA | reporter.nih.gov |
| A comprehensive imaging genetics framework for osteoarthritis research | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $705,837 | February 21, 2024 | January 31, 2029 | NIETHAMMER, MARC | reporter.nih.gov |
| Prognosis and Predictors of ACL Reconstruction: A Multicenter Cohort Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $703,753 | September 22, 2006 | September 15, 2024 | SPINDLER, KURT PAUL | reporter.nih.gov |
| Development and Translation of Granulated Human-Derived Biomaterials for Integrative Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $703,625 | September 1, 2023 | June 30, 2025 | NEU, COREY P | reporter.nih.gov |
| The longitudinal relationship of sedentary behavior with health outcomes in a community-based cohort: The Johnston County Health Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $700,970 | September 23, 2022 | August 31, 2024 | WHITE, DANIEL K | reporter.nih.gov |
| FGF2 Isoforms in Bone and Phosphate Homeostasis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $699,395 | September 17, 2013 | December 31, 2023 | HURLEY, MARJA MARIE | reporter.nih.gov |
| A phenotypic screen for osteoarthritic pain therapeutics using all-optical electrophysiology. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $696,518 | September 20, 2019 | March 31, 2024 | ZHANG, HONGKANG | reporter.nih.gov |
| The Role of Sodium Channel Nav1.7 in Osteoarthritis - Resubmission - 1 | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $695,383 | July 1, 2022 | May 31, 2027 | LIU, CHUANJU | reporter.nih.gov |
| Triangulating Mechanisms of Microbiome-Joint Crosstalk | NIH | National Institute on Aging | 2025 | $694,824 | August 1, 2025 | May 31, 2030 | HERNANDEZ, CHRISTOPHER JOHN | reporter.nih.gov |
| The role of mechanosensing and mechanotransduction in joint homeostasis and osteoarthritis susceptibility | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $691,089 | July 15, 2025 | June 30, 2030 | JURYNEC, MICHAEL J | reporter.nih.gov |
| An integrated nano- and micro-indentation system for musculoskeletal tissue and biomaterials | NIH | Office of the Director, National Institutes of Health | 2023 | $691,040 | April 1, 2023 | March 31, 2025 | LIU, XIAOWEI SHERRY | reporter.nih.gov |
| Deep Learning Reconstruction for Rapid Multi-Component Relaxometry | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2024 | $689,578 | April 1, 2022 | December 31, 2025 | LIU, FANG | reporter.nih.gov |
| Analyzing the role of cAMP and STAT3 signaling in cartilage homeostasis and osteoarthritis development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $685,813 | March 14, 2023 | February 28, 2026 | LIU, ZHAOYANG | reporter.nih.gov |
| Laser Treatment Modality for Strengthening Osteoarthritic Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $682,818 | January 10, 2019 | December 31, 2023 | ATESHIAN, GERARD A. | reporter.nih.gov |
| Nanoparticle targeting within the joint for site-specific delivery of osteoarthritis therapeutics | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $682,361 | April 1, 2018 | March 31, 2025 | SHARMA, BLANKA | reporter.nih.gov |
| Leveraging human musculoskeletal development to identify causal disease variants | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $676,841 | August 1, 2025 | July 31, 2030 | CAPELLINI, TERENCE D | reporter.nih.gov |
| Ultrashort Echo Time Magnetic Resonance Imaging of the Knee Joint | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $675,131 | August 1, 2025 | June 30, 2030 | DU, JIANG | reporter.nih.gov |
| Network medicine-based discovery of therapeutics for knee osteoarthritis | NIH | National Institute on Aging | 2025 | $665,970 | August 1, 2025 | May 31, 2030 | IIJIMA, HIROTAKA | reporter.nih.gov |
| Metabolites of Dietary Intake and Risk of Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $662,673 | July 5, 2019 | December 6, 2021 | LU, BING | reporter.nih.gov |
| Environmental Factors Associated with the Development of Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $659,439 | February 1, 2023 | January 31, 2024 | DRIBAN, JEFFREY B | reporter.nih.gov |
| Defining TMJ cartilage progenitors and their regulatory niche for TMJ regeneration | NIH | National Institute of Dental & Craniofacial Research | 2025 | $655,455 | September 11, 2025 | September 10, 2027 | EMBREE, MILDRED CHRISTINE | reporter.nih.gov |
| Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $653,546 | August 5, 2022 | July 31, 2026 | RIGGS, KEVIN | reporter.nih.gov |
| Development of Dual-Action Nanoparticle-Loaded Microparticles for Osteoarthritis Treatment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $646,506 | September 5, 2025 | June 30, 2030 | CHENG, ZHILIANG | reporter.nih.gov |
| Discovering the Mechanisms Linking Gait to Osteoarthritis Onset and Progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $644,152 | January 20, 2025 | December 31, 2029 | PIETROSIMONE, BRIAN | reporter.nih.gov |
| Neuroplastic Mechanisms for Acquisition and Transfer of Injury-Resistant Movement Patterns Assessed in VR Simulated Sport | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $643,749 | February 17, 2021 | March 31, 2025 | MYER, GREGORY DONALD | reporter.nih.gov |
| Ultra-Fast High-Resolution Multi-Parametric MRI for Characterizing Cartilage Extracellular Matrix | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $643,218 | September 21, 2023 | August 31, 2025 | LIU, FANG | reporter.nih.gov |
| Mechano-regulation of circulating extracellular vesicle cargoes to enhance knee joint health | NIH | National Institute on Aging | 2025 | $639,997 | May 15, 2025 | March 31, 2030 | IIJIMA, HIROTAKA | reporter.nih.gov |
| Neighborhood Barriers and Facilitators to Walking, the Epidemiology of Knee Osteoarthritis and Developing Effective Exercise Prescriptions | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $629,684 | April 1, 2022 | January 31, 2027 | GEBAUER, SARAH | reporter.nih.gov |
| Knee Arthrosis after ACL Reconstruction: A Long-term Cohort Study with Matched Controls | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $624,808 | May 10, 2019 | October 31, 2024 | FLEMING, BRADEN C | reporter.nih.gov |
| Mediators of the OA Cascade in the Pre-Arthritic Hip | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $622,820 | September 4, 2020 | August 31, 2025 | PASCUAL-GARRIDO, CECILIA | reporter.nih.gov |
| Subchondral Bone Cavities in Osteoarthritis Pain | NIH | National Institute on Aging | 2024 | $620,588 | September 30, 2020 | August 31, 2025 | CAO, XU | reporter.nih.gov |
| Classification of Ankle Osteoarthritis Severity from Weightbearing Computed Tomography Using Statistical Shape Modeling and Machine Learning | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $606,892 | August 1, 2022 | June 30, 2027 | LENZ, AMY L. | reporter.nih.gov |
| Movement pattern biofeedback training after total knee arthroplasty | NIH | National Institute on Aging | 2021 | $605,873 | September 15, 2017 | April 30, 2025 | STEVENS-LAPSLEY, JENNIFER E. | reporter.nih.gov |
| Genicular Artery Embolization for Reducing Pain in Medically Refractory Mild to Moderate Osteoarthritis: A Double-Blind, Randomized Sham-Controlled Pilot Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $602,761 | September 20, 2024 | August 31, 2026 | AHMED, OSMAN | reporter.nih.gov |
| Equipment upgrade for 7T Small Animal MRI system | NIH | Office of the Director, National Institutes of Health | 2022 | $600,000 | August 15, 2022 | August 14, 2023 | LIU, THOMAS T | reporter.nih.gov |
| Injectable cell-free piezoelectric scaffold to treat osteoarthritis in large animal models | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $597,683 | May 6, 2025 | April 30, 2029 | NGUYEN, THANH | reporter.nih.gov |
| Imaging Biomarkers of Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $588,710 | August 1, 2016 | April 30, 2023 | REGATTE, RAVINDER | reporter.nih.gov |
| Metabolites of Dietary Intake and Risk of Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $586,486 | July 5, 2019 | May 31, 2025 | LU, BING | reporter.nih.gov |
| Metalloproteins: evolution, catalysis and material design | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $585,959 | September 5, 2024 | August 31, 2029 | MAKHLYNETS, OLGA | reporter.nih.gov |
| Zonal-Specific Mineralized Scaffolds for Osteochondral Regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $570,174 | September 15, 2025 | August 31, 2028 | YU, LE | reporter.nih.gov |
| Hip Chondromics: Comprehensive Cartilage Characterization with MR Fingerprinting | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $561,901 | September 15, 2016 | July 31, 2023 | LATTANZI, RICCARDO | reporter.nih.gov |
| Walk this Way: Physical Activity and Walking Biomechanics Lead to Early Knee OA Symptoms and Ultrasound-Detected Structural Pathology after ACL Reconstruction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $561,655 | August 1, 2022 | May 31, 2027 | HARKEY, MATTHEW | reporter.nih.gov |
| Discovery of the Neural Drivers Underlying Injury-Risk Biomechanics | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $557,077 | May 15, 2021 | March 31, 2025 | GROOMS, DUSTIN ROBERT | reporter.nih.gov |
| Effects of Vitamin K on Lower-extremity Function in Adults with Osteoarthritis: a Randomized Controlled Pilot Trial | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $555,020 | September 21, 2022 | August 31, 2025 | BOOTH, SARAH LOUISE | reporter.nih.gov |
| Computer-guided Action Planning to Support Physical Activity (CAPPA) for Employees with Chronic Knee Symptoms | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $552,272 | December 21, 2022 | November 30, 2025 | PINTO, DANIEL | reporter.nih.gov |
| Optimizing Osteoarthritis Care through Clinical and Community Partnership | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $547,360 | December 15, 2021 | November 30, 2024 | ALLEN, KELLI D. | reporter.nih.gov |
| Automated Arthroscopic Partial Meniscectomy Patient Outcome Prediction using Deep Learning | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $544,570 | July 1, 2022 | June 30, 2027 | YANG, MINGRUI | reporter.nih.gov |
| Early Detection and Monitoring of Osteonecrosis of the Femoral Head | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $541,108 | September 22, 2021 | January 31, 2024 | JOHNSON, CASEY PETER | reporter.nih.gov |
| JAK Specific Signaling in PTOA-associated Joint Degeneration and Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $540,974 | September 19, 2025 | August 31, 2030 | HILTON, MATTHEW J. | reporter.nih.gov |
| Quadriceps Muscle Quality: A Post-Injury Determinant of Knee Function and Health | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $539,150 | July 26, 2023 | June 30, 2026 | PIETROSIMONE, BRIAN | reporter.nih.gov |
| Developing a nonpharmacological pain intervention for community dwelling older adults with dementia | NIH | National Institute on Aging | 2023 to 2025 | $534,580 | April 15, 2023 | March 31, 2027 | NA, ANNALISA | reporter.nih.gov |
| Quantitative magnetic resonance imaging in patients with femoroacetabular impingement syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $533,949 | January 17, 2024 | December 31, 2026 | ANDERSON, ANDREW EDWARD | reporter.nih.gov |
| The OAI Collaborative Osteoarthritis Research Enterprise (OAI CORE) Knowledgebase | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $533,151 | April 1, 2025 | March 31, 2029 | DRIBAN, JEFFREY B | reporter.nih.gov |
| Regenerating Hyaline Cartilage Using Nanofibrous Hollow Microspheres and Synergizing TGF-beta and HIF | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $523,257 | September 23, 2020 | November 30, 2024 | SCHIPANI, ERNESTINA | reporter.nih.gov |
| Development of a Mind Body Program to Reduce Knee Pain in Obese Osteoarthritis Patients with Comorbid Depression | NIH | National Center for Complementary & Integrative Health | 2021 to 2022 | $522,915 | January 1, 2020 | December 31, 2023 | CONLEY, CAITLIN ELIZABETH-WHALE | reporter.nih.gov |
| Biomechanical Markers of PTOA after ACL Reconstruction and Meniscal Resection | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $521,149 | February 8, 2021 | August 31, 2025 | FIORENTINO, NICCOLO M | reporter.nih.gov |
| Determining the effects of non-invasive brain stimulation to improve quadriceps muscle function after ACL reconstruction. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $520,154 | June 6, 2025 | May 5, 2028 | MCCLURE, PHILIP W | reporter.nih.gov |
| The role of maternal obesity in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $512,336 | April 5, 2022 | March 31, 2027 | OESTREICH, ARIN KETTLE | reporter.nih.gov |
| Quantifying the Mechanism and Impact of Hip Extensor Muscle Dysfunction During Aerobic Exercise in Hip Osteoarthritis | NIH | National Institute on Aging | 2022 to 2025 | $511,932 | August 1, 2022 | June 30, 2027 | SAMAAN, MICHAEL A | reporter.nih.gov |
| Role of hyaluronan in YAP signaling on TMJ health and pathology | NIH | National Institute of Dental & Craniofacial Research | 2025 | $507,006 | August 1, 2025 | July 31, 2027 | KOYAMA, EIKI | reporter.nih.gov |
| Swelling Management after Total Knee Arthroplasty | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $503,695 | August 2, 2023 | June 30, 2027 | BADE, MICHAEL J | reporter.nih.gov |
| Graft harvest as a model of tendon injury; Trajectory of recovery and clinical outcomes | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $501,327 | August 1, 2022 | July 31, 2027 | SPRAGUE, ANDREW L | reporter.nih.gov |
| Real-time measurement of joint-loading for osteoarthritis study and treatment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $498,363 | March 1, 2021 | February 29, 2024 | NGUYEN, THANH | reporter.nih.gov |
| Predicting patient-reported outcomes in patients with pre-arthritic hip disorders | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $496,392 | August 1, 2019 | June 30, 2024 | CHENG, ABBY LING-LEE | reporter.nih.gov |
| Pathogenic mechanisms of TMJ osteophyte formation | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $489,500 | August 1, 2024 | July 31, 2027 | KOYAMA, EIKI | reporter.nih.gov |
| Asymmetric Walking Protocol for Optimal Post-ACL Reconstruction Rehabilitation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $487,980 | September 1, 2022 | July 31, 2027 | MORGAN, KRISTIN | reporter.nih.gov |
| Tai Chi and Gut Microbiota in Metabolic Osteoarthritis | NIH | National Center for Complementary & Integrative Health | 2022 to 2023 | $487,940 | May 1, 2022 | April 30, 2025 | WANG, CHENCHEN | reporter.nih.gov |
| Effects of Blood and Blood-Derived Products on Meniscus Healing | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $487,652 | September 1, 2025 | August 31, 2030 | MCNULTY, AMY L | reporter.nih.gov |
| Roles of the superficial zone in mature articular cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $485,455 | May 1, 2024 | April 30, 2027 | RUX, DANIELLE RENAE | reporter.nih.gov |
| Combination Therapy of Home-based Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms in Older Adults with Knee Osteoarthritis | NIH | National Institute of Nursing Research | 2021 | $485,097 | April 14, 2020 | August 15, 2021 | AHN, HYOCHOL | reporter.nih.gov |
| Knee evaluation under mechanical loading by cones ultrashort echo time MR imaging | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $481,539 | April 5, 2022 | March 31, 2027 | JERBAN, SAEED | reporter.nih.gov |
| Endogenous stem cells in jaw joint cartilage and ligament regeneration | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2022 | $479,592 | September 1, 2020 | August 31, 2024 | SMEETON, JOANNA MARJORIE | reporter.nih.gov |
| The Role of Inflammation in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $476,280 | April 1, 2022 | March 31, 2027 | MACFARLANE, LINDSEY A. | reporter.nih.gov |
| Single-administration microneedles with controlled sustained release of non-opioid analgesics to treat osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $474,262 | May 5, 2022 | April 30, 2025 | NGUYEN, THANH | reporter.nih.gov |
| Acquisition of a laser microtomy system for hard tissue histology | NIH | Office of the Director, National Institutes of Health | 2024 | $462,680 | May 15, 2024 | May 14, 2026 | SUMNER, D RICK | reporter.nih.gov |
| High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) Scanner | NIH | Office of the Director, National Institutes of Health | 2023 | $460,000 | April 15, 2023 | April 14, 2024 | NYMAN, JEFFRY STEPHEN | reporter.nih.gov |
| 4D CT Imaging for Improved Diagnosis and Treatment of Wrist Ligament Injuries | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $459,420 | May 1, 2017 | June 30, 2022 | ZHAO, KRISTIN DAIGLE | reporter.nih.gov |
| Spatial Proteomics of osteoarthritis in bones to uncover disease progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $456,808 | September 18, 2024 | August 31, 2026 | SCHILLING, BIRGIT | reporter.nih.gov |
| Pixelated scintillators for ultra-high resolution cone-beam CT | NIH | National Institute of Biomedical Imaging and Bioengineering | 2024 to 2025 | $453,907 | July 15, 2024 | June 30, 2027 | ZBIJEWSKI, WOJCIECH BARTOSZ | reporter.nih.gov |
| Obesity promoting protein malonylation and chondrocyte metabolic dysfunction in osteoarthritis development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $453,000 | August 1, 2022 | July 31, 2025 | ZHU, SHOUAN | reporter.nih.gov |
| Impact of mast cell heterogeneity on Osteoarthritis | NIH | National Institute on Aging | 2024 | $452,437 | August 15, 2024 | July 31, 2026 | ZENG, LI | reporter.nih.gov |
| Estrogen modulation of chondrocyte mechanotransduction via PIEZO1 and TRPV4 | NIH | National Institute on Aging | 2025 | $451,000 | May 15, 2025 | April 30, 2027 | HERNANDEZ, PAULA ANDREA | reporter.nih.gov |
| Quantitative, Image-Based Osteoarthritis Biomarkers Software Resubmission | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $445,896 | September 1, 2019 | August 31, 2023 | MCCORMICK, MATTHEW | reporter.nih.gov |
| Device Automation of an FDA-cleared CD-Microfluidic Platform for Rapid Tissue Microsizing | NIH | National Center for Advancing Translational Sciences | 2024 | $441,060 | March 15, 2024 | December 14, 2024 | ZOBI, AHMED NABIL | reporter.nih.gov |
| Neural mechanisms underlying psychosocial contributions to ethnic group differences in pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $440,411 | April 15, 2018 | March 31, 2024 | TERRY, ELLEN L. | reporter.nih.gov |
| Intraarticular microbial DNA as a novel mediator of osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $437,000 | September 8, 2020 | August 31, 2024 | JEFFRIES, MATLOCK | reporter.nih.gov |
| A Lower Extremity Neuromusculoskeletal Human Simulator: Addressing Multiscale Challenges | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $436,473 | September 7, 2018 | May 31, 2024 | SHELBURNE, KEVIN B | reporter.nih.gov |
| The Role of Calcitonin Gene-Related Peptide in rapidly progressive osteoarthritis induced by anti-nerve growth factor | NIH | National Institute on Aging | 2022 to 2023 | $435,875 | June 1, 2022 | March 31, 2025 | FEHRENBACHER, JILL C | reporter.nih.gov |
| Evaluating the Potential of Human Induced Pluripotent Stem Cells (hiPSC) For Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $435,442 | July 5, 2017 | June 30, 2023 | BHUTANI, NIDHI | reporter.nih.gov |
| Understanding how age, knee osteoarthritis, and symptoms influence the structure and variance of real-world gait mechanics | NIH | National Institute on Aging | 2022 to 2023 | $434,761 | May 15, 2022 | February 28, 2025 | HAFER, JOCELYN FREY | reporter.nih.gov |
| Degradomics of proteolytic mechanisms in post-traumatic osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $434,682 | August 22, 2025 | June 30, 2030 | APTE, SUNEEL S | reporter.nih.gov |
| Exploring nano-bio interactions for cell-specific targeting of osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $429,384 | September 20, 2024 | August 31, 2026 | ZENG, LI | reporter.nih.gov |
| Factors Regulating Development of Appendicular Skeletal Progenitors | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $429,000 | February 11, 2015 | August 31, 2024 | DUESTER, GREGG L | reporter.nih.gov |
| Notch Signaling in Joint Cartilage Maintenance and Arthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $427,291 | July 2, 2012 | July 31, 2022 | HILTON, MATTHEW J. | reporter.nih.gov |
| Does joint lavage reduce intraarticular inflammation in high-energy tibial pilon fractures? | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $427,288 | August 5, 2022 | July 31, 2025 | WHEATLEY, BENJAMIN M | reporter.nih.gov |
| Cannabinoid Effects on Sleep and Pain Mechanisms in Osteoarthritis of the Knee | NIH | National Institute on Drug Abuse | 2021 to 2023 | $427,278 | July 15, 2020 | June 30, 2024 | BOEHNKE, KEVIN FOXMAN | reporter.nih.gov |
| Molecular Regulatory Mechanism of a Cartilage-Enriched GPCR in Joint Maintenance | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $426,889 | April 10, 2025 | March 31, 2030 | LIU, ZHAOYANG | reporter.nih.gov |
| Telehealth Exercise and Mindfulness of Pain in knee Osteoarthritis (TEMPO): A digital Feasibility Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $426,698 | August 1, 2024 | July 31, 2027 | KUMAR, DEEPAK | reporter.nih.gov |
| Development of an Organoid-Derived Exosome Product for the Treatment of Osteoarthritis | NIH | National Institute on Aging | 2024 | $426,250 | August 15, 2024 | July 31, 2026 | RAMACHANDRAN, SABARINATHAN | reporter.nih.gov |
| Regulation of limb synovial joint organization and function | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $425,920 | August 1, 2022 | July 31, 2025 | PACIFICI, MAURIZIO | reporter.nih.gov |
| Role of the Infrapatellar Fat Pad in the Development of Post-Traumatic Osteoarthritis Following Blunt Impact to the Knee Joint | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $425,298 | July 1, 2023 | June 30, 2026 | WILLIAMS, JOHN LEICESTER | reporter.nih.gov |
| Intraarticular microbial DNA as a novel mediator of osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $423,890 | September 8, 2020 | August 31, 2022 | JEFFRIES, MATLOCK | reporter.nih.gov |
| Mi-SPA: Michigan Split-belt Adaptation Paradigm to Improve Knee Loading After Anterior Cruciate Ligament Reconstruction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $423,727 | February 15, 2024 | January 31, 2027 | PALMIERI-SMITH, RIANN MARIE | reporter.nih.gov |
| Molecular Mechanism by which Notch Signaling regulates TMJ Osteoarthritis | NIH | National Institute of Dental & Craniofacial Research | 2025 | $419,379 | August 8, 2025 | May 31, 2030 | YADAV, SUMIT | reporter.nih.gov |
| The peripheral blood microbiome as a potential biomarker of knee osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $412,610 | September 26, 2024 | August 31, 2026 | JEFFRIES, MATLOCK | reporter.nih.gov |
| The role of microRNAs in cartilage homeostasis and osteoarthritis arthritis treatment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $410,795 | July 1, 2004 | June 30, 2022 | ASAHARA, HIROSHI | reporter.nih.gov |
| Osteocyte-dependent mechanisms of bone cartilage crosstalk in osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $408,669 | September 1, 2023 | August 31, 2025 | AKBAS KAYA, AYSE SERRA | reporter.nih.gov |
| Regulation of Inflammation by IL1RN polymorphisms | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $408,326 | March 1, 2021 | February 29, 2024 | ABRAMSON, STEVEN B | reporter.nih.gov |
| Elucidating the neural oscillations of the sensory-discriminative and affective-motivational dimensions of pain. | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $408,000 | September 23, 2024 | August 31, 2027 | HARRIS BOZER, AMBER | reporter.nih.gov |
| STepped Exercise Program for Knee Osteoarthritis: The STEP-KOA Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $407,357 | April 1, 2024 | March 31, 2026 | ALLEN, KELLI D. | reporter.nih.gov |
| Bioerodible corticosteroid microparticle-drug as an intra-articular drug delivery system for osteoarthritis therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $404,933 | September 23, 2022 | August 31, 2025 | MAERZ, TRISTAN | reporter.nih.gov |
| Role of NOTCH2 in Articular Inflammation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $404,187 | May 14, 2025 | March 31, 2030 | CANALIS, ERNESTO | reporter.nih.gov |
| Repressing Retrotransposon LINE-1: New Concepts for Osteoarthritis Treatment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $396,670 | September 16, 2019 | August 31, 2024 | CHEN, QIAN | reporter.nih.gov |
| Effect of Osseointegrated Prostheses on the Pathogenesis of Hip Osteoarthritis in Patients with Lower Limb Loss | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $394,875 | March 3, 2023 | December 31, 2027 | GAFFNEY, BRECCA | reporter.nih.gov |
| Application of SHP2 PROTAC to Mitigate Articular Cartilage Degeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $394,064 | September 1, 2022 | August 31, 2025 | YANG, WENTIAN | reporter.nih.gov |
| Muscle Power as a Predictor of Knee Osteoarthritis in At-Risk Females | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $393,883 | May 14, 2025 | April 30, 2029 | RICE, PAIGE ELIZABETH | reporter.nih.gov |
| Fat and synovial tissue remodeling in joint osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $393,250 | September 22, 2021 | August 31, 2024 | QIN, LING | reporter.nih.gov |
| Data-driven approaches in defining knee osteoarthritis phenotypes and factorsassociated with fast progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $392,850 | July 2, 2020 | June 30, 2025 | COLLINS, JAMIE E. | reporter.nih.gov |
| A novel approach to ultralong sustained delivery of punicalagin as a potential treatment for osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $391,218 | June 1, 2024 | May 31, 2027 | ELDER, STEVEN HOWARD | reporter.nih.gov |
| Validation of the Yucatan Minipig as a Preclinical Model for Wrist Bone Arthroplasty | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $390,386 | January 1, 2023 | December 31, 2024 | CRISCO, JOSEPH J | reporter.nih.gov |
| A Novel Glycosaminoglycan Mimetic Scaffold for Cartilage Repair - diversity supplement | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $389,902 | June 1, 2021 | February 28, 2026 | ARINZEH, TREENA LYNNE | reporter.nih.gov |
| The proteolytic landscape of osteoarthritic cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $389,620 | April 10, 2022 | March 31, 2025 | APTE, SUNEEL S | reporter.nih.gov |
| Real-Time Sensorimotor Feedback for Injury Prevention Assessed in Virtual Reality | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $388,312 | August 1, 2016 | July 31, 2022 | MYER, GREGORY DONALD | reporter.nih.gov |
| Exercise Induced Muscle Secreted Factors That Modify Osteoarthritis (OA) Severity | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $387,495 | September 22, 2021 | June 30, 2023 | ALMAN, BENJAMIN AARON | reporter.nih.gov |
| Racial Disparities in Analgesic Prescribing for Post-Surgical Pain Management among Older Americans following Hip and Knee Replacement Surgeries | NIH | National Institute on Aging | 2022 to 2023 | $386,874 | September 1, 2022 | July 8, 2024 | THIRUKUMARAN, CAROLINE PINTO | reporter.nih.gov |
| Integrin Function in Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $386,356 | August 1, 2002 | July 31, 2023 | LOESER, RICHARD F | reporter.nih.gov |
| Macrophage Anchoring Nanomedicine to Replace Steroids for Intra-articular Injection | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $384,435 | March 15, 2023 | February 28, 2026 | JIN, LI | reporter.nih.gov |
| PHLPP inhibition and Osteoarthritis-Associated Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $379,533 | February 1, 2023 | December 31, 2024 | WESTENDORF, JENNIFER J | reporter.nih.gov |
| Genome and epigenome editing of induced pluripotent stem cells for investigating osteoarthritis risk alleles | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $378,510 | September 22, 2022 | August 31, 2025 | GUILAK, FARSHID | reporter.nih.gov |
| Validation of the Pathomechanics and Biology of a Novel Pre-Clinical Rabbit Model for Hip Pre-Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $378,228 | September 10, 2025 | August 31, 2027 | PASCUAL-GARRIDO, CECILIA | reporter.nih.gov |
| Topography matching for osteochondral graft transplantation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $378,213 | May 7, 2021 | April 30, 2023 | INOUE, NOZOMU | reporter.nih.gov |
| Fetuin-A in post-traumatic osteoarthritis: at the crossroad between joint and muscle degeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $378,003 | September 24, 2021 | August 31, 2024 | LONGOBARDI, LARA | reporter.nih.gov |
| Can circulating bile acids predict knee OA progression? | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $377,589 | April 1, 2023 | January 31, 2026 | GUMA, MONICA | reporter.nih.gov |
| Targeting Pathological Angiogenesis after Joint Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $377,520 | September 22, 2021 | August 31, 2024 | MAERZ, TRISTAN | reporter.nih.gov |
| SMART stem cells that autonomously down-modulate TFG-β signaling for Articular Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $376,018 | March 15, 2022 | January 31, 2024 | HUARD, JOHNNY | reporter.nih.gov |
| In situ and real-time readout of nuclear mechanotransduction via single cell mechanics and site-specific fluorescence reporting | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $375,092 | September 15, 2023 | August 31, 2025 | HAUDENSCHILD, DOMINIK R | reporter.nih.gov |
| Albumin Binding siRNAs for Systemic Treatment of Multi-Joint Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $374,205 | February 19, 2021 | January 31, 2024 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Programmed cells for targeted articular regenerative medicine | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $374,188 | July 1, 2021 | May 31, 2024 | BRUNGER, JONATHAN MATTHEW | reporter.nih.gov |
| CD10-bound Exosomes from IFP-MSC Degrade Substance P Controlling OA Inflammation and Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $371,470 | July 18, 2022 | June 30, 2024 | KOUROUPIS, DIMITRIOS | reporter.nih.gov |
| A Feasibility and Pilot Study of Combined Treatment Protocol using Aerobic Exercise and Duloxetine in Older Adults with Symptomatic Knee Osteoarthritis and Comorbid Depression | NIH | National Institute on Aging | 2021 to 2023 | $371,193 | July 15, 2019 | February 28, 2025 | RATHBUN, ALAN MICHAEL | reporter.nih.gov |
| Functional interrogation of putative osteoarthritis causal variants | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $371,179 | April 1, 2024 | March 31, 2027 | DIEKMAN, BRIAN O | reporter.nih.gov |
| Peptide Discovery for Chondrogenesis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $368,850 | April 1, 2022 | March 31, 2025 | ACAR, HANDAN | reporter.nih.gov |
| Cellular heterogeneity and niche regulation in TMJ | NIH | National Institute of Dental & Craniofacial Research | 2025 | $368,438 | September 4, 2025 | May 31, 2030 | LIM, JOOHYUN JASON | reporter.nih.gov |
| Dissecting Neural Circuits Involved in Musculoskeletal Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $367,103 | January 1, 2021 | June 30, 2024 | PETERS, CHRISTOPHER MICHAEL | reporter.nih.gov |
| Functional follow-up of a genetic variant associated with high risk of osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $367,025 | September 22, 2021 | August 31, 2024 | DIEKMAN, BRIAN O | reporter.nih.gov |
| Introducing a Chondroinductive Peptide | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $366,350 | September 24, 2021 | August 31, 2024 | DETAMORE, MICHAEL S. | reporter.nih.gov |
| CRISPR-Cas9 Genome Edited MSCs to Target OA Cartilage Regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $365,803 | September 22, 2022 | August 31, 2023 | PEI, MING | reporter.nih.gov |
| Extracellular RNA Expression Biomarkers in Osteoarthritis Disease and Progression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $364,286 | February 22, 2023 | January 31, 2026 | GRISWOLD, ANTHONY JOHN | reporter.nih.gov |
| Steps Towards OA Prevention | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $363,799 | August 15, 2023 | July 31, 2028 | LISEE, CAROLINE M | reporter.nih.gov |
| Advanced MR Imaging of Early Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $361,547 | April 1, 2012 | February 29, 2024 | GOLD, GARRY E | reporter.nih.gov |
| Targeting Signaling Pathways with Small Molecules in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $361,300 | August 1, 2025 | July 31, 2027 | LOESER, RICHARD F | reporter.nih.gov |
| Using STRAINS, a big data method that analyzes the spatiotemporal distribution of cell phenotypes, to investigate mechanotransduction pathways in injured cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $359,717 | September 5, 2024 | August 31, 2026 | COHEN, ITAI | reporter.nih.gov |
| Engineering Spatiotemporal Osteochondral Tissue Formation with Tunable 3D-Printed Scaffolds | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $359,473 | June 1, 2022 | March 31, 2026 | CHOW, LESLEY W | reporter.nih.gov |
| Small molecule stimulation of lubricin for treatment of post-traumatic osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $358,459 | August 15, 2024 | August 14, 2027 | KEAN, THOMAS J. | reporter.nih.gov |
| Elucidating Social Determinants and Mental Health Needs to Achieve Equity in Rheumatic Disease Care | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $358,000 | September 18, 2023 | August 31, 2025 | COSTENBADER, KAREN H | reporter.nih.gov |
| Physical Activity Pathway for Patients with Osteoarthritis in Primary Care | NIH | National Institute on Aging | 2021 | $357,690 | June 1, 2018 | May 31, 2024 | ALLEN, KELLI D. | reporter.nih.gov |
| Evaluating Over Constraint of the Patella following MPFL Reconstruction as a Contributing Factor to Progressive Cartilage Degradation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $356,213 | August 1, 2024 | May 31, 2028 | ELIAS, JOHN J | reporter.nih.gov |
| Autonomous RUNX2 suppression in genetically modified stem cell-derived chondrocytes as a disease modifying therapeutic for PTOA | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $355,513 | March 3, 2023 | January 31, 2026 | COLEMAN, RHIMA | reporter.nih.gov |
| Identification and application of targeting peptides for systemic nanoparticle delivery to osteoarthritic joints | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $351,514 | July 11, 2024 | June 30, 2027 | SHARMA, BLANKA | reporter.nih.gov |
| Engineered Biotherapeutic Agent for Treatment of Post-Traumatic Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $350,922 | September 25, 2023 | August 31, 2026 | CHAUGULE, JUI SHIVAJI | reporter.nih.gov |
| Unraveling the discordance between structural damage and pain phenotypes in knee osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $349,378 | July 1, 2024 | June 30, 2029 | JARRAYA, MOHAMED | reporter.nih.gov |
| Computational Tools for Predicting and Understanding Knee Pain Spatial Patterns | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $348,680 | September 26, 2024 | August 31, 2026 | SUN, XIAOXIAO | reporter.nih.gov |
| The role of vitamin K in knee osteoarthritis outcomes | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $346,143 | September 20, 2024 | August 31, 2029 | LIEW, JEAN WAI | reporter.nih.gov |
| Opposing RNAi Molecule Gradient Constructs to Repair Osteochondral Defects | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $341,226 | April 1, 2019 | March 31, 2023 | ALSBERG, EBEN | reporter.nih.gov |
| Real time biofeedback Tai Chi training for knee osteoarthritis: A feasibility study | NIH | National Center for Complementary & Integrative Health | 2021 to 2022 | $329,680 | August 15, 2018 | July 31, 2024 | LIU, WEI | reporter.nih.gov |
| Intra-Articular Delivery of Sustained Release NF-kB Antagonists in Arthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $327,527 | February 1, 2017 | January 31, 2023 | SETTON, LORI A. | reporter.nih.gov |
| Mentorship of Junior Investigators on HEAL-SKOAP | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $323,998 | September 24, 2021 | August 31, 2025 | CAMPBELL, CLAUDIA MICHELLE | reporter.nih.gov |
| The Therapeutic Role of GPNMB in Osteoarthritis | NIH | National Institute on Aging | 2021 | $319,822 | September 30, 2021 | March 29, 2024 | BALL, HOPE | reporter.nih.gov |
| Ultrasound Stimulated Chondrogenic Stem Cell Therapy for Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $319,267 | September 22, 2023 | August 31, 2025 | ANAGANTI, SURESH | reporter.nih.gov |
| Understanding the role of cellular senescence in osteoarthritis: dynamics, clearance, and mechanisms of induction | NIH | National Institute on Aging | 2021 | $316,162 | September 30, 2021 | August 31, 2022 | DIEKMAN, BRIAN O | reporter.nih.gov |
| Development of a Standardized, Reliable and Easy-to-Use Clinical Instrument to Measure First Ray Mobility and Position of the Medial Forefoot to Assist with Clinical Decisions and Treatments | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $314,613 | September 16, 2022 | August 31, 2023 | HILLSTROM, RAJSHREE | reporter.nih.gov |
| Intraarticular injection of Wnt inhibitor for osteoarthritis therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $314,363 | September 16, 2025 | August 31, 2026 | CHEN, MO | reporter.nih.gov |
| Arthrofibrosis control using small molecule inhibitors of interleukin-11 | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $314,362 | September 22, 2025 | August 31, 2027 | SWINDLEHURST, CATHY A | reporter.nih.gov |
| Novel Computational Biomechanics Approach to Design of Bioengineered Tissue Construct for Meniscus Defect Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $313,830 | July 20, 2018 | May 31, 2023 | JACKSON, ALICIA R | reporter.nih.gov |
| A Machine Learning Software Tool for Automatic Segmentation and Analysis of T1p MR Images of Knee Cartilage for OA Diagnosis and Treatment Monitoring | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $313,358 | August 1, 2025 | March 31, 2027 | SARKAR, SUSANTA K | reporter.nih.gov |
| Pre-Clinical Assessment of a Minimally Invasive Meniscus Implant to Delay Arthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $303,905 | September 21, 2023 | December 31, 2024 | SCHWARTZ, JONATHAN | reporter.nih.gov |
| Using Augmented Reality illusion therapy to develop a non-opioid chronic pain digital treatment | NIH | National Institute on Drug Abuse | 2021 to 2022 | $303,366 | September 1, 2021 | March 1, 2023 | LAFFERTY, PAUL | reporter.nih.gov |
| CollaLink: Guided-regenerative Scaffold for Augmentation of Anterior Cruciate Ligament Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $300,000 | September 1, 2023 | August 31, 2025 | SHANKAR, SUBBA | reporter.nih.gov |
| A BioAdhesive to Localize and Direct Stem Cells to Treat Damaged Cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $299,574 | September 20, 2021 | February 28, 2023 | TSINMAN, ANTONINA | reporter.nih.gov |
| Mentoring and Research in Translational Science of Integrative Medicine | NIH | National Center for Complementary & Integrative Health | 2024 to 2025 | $299,100 | September 1, 2016 | August 31, 2029 | LAVRETSKY, HELEN | reporter.nih.gov |
| Bionanomatrix coating to enhance antibacterial effects while reducing inflammation of knee joint implants | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $292,643 | September 19, 2023 | August 31, 2025 | SHERWOOD, JENNIFER | reporter.nih.gov |
| Developing a stable cell line expressing recombinant sclerostin | NIH | National Institute of Dental & Craniofacial Research | 2022 | $290,002 | September 20, 2022 | September 16, 2024 | CHEN, MO | reporter.nih.gov |
| Novel models to study dorsal root ganglion neurons in knee osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $288,516 | October 1, 2024 | June 30, 2025 | BREWER, CHELSIE L | reporter.nih.gov |
| Mechanisms underlying sex differences in emergence of advanced osteoarthritis pain | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $284,000 | August 1, 2024 | June 30, 2028 | KING, TAMARA E | reporter.nih.gov |
| Development of Nicotinamide-Riboside plus Pterostilbene as a Disease Modifying Osteoarthritis Therapeutic | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $283,071 | June 1, 2023 | May 31, 2026 | DELLINGER, RYAN WILLIAM | reporter.nih.gov |
| Addressing bone marrow lesions that compromise osteochondral tissue repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $282,265 | September 18, 2023 | August 31, 2025 | WILLARD, VINCENT P | reporter.nih.gov |
| Skeletal Muscle Remodeling and Intramuscular Adipose Tissue following Traumatic Knee Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $278,100 | July 20, 2024 | June 30, 2029 | BODKIN, STEPHAN G | reporter.nih.gov |
| In situ Cell Engineering for On-demand TIMP Expression in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $275,790 | July 15, 2021 | June 30, 2025 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Pre-Clinical Optimization of MeniscoFix, a Novel Total Meniscus Replacement Implant | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $275,546 | July 15, 2022 | June 30, 2024 | WEADOCK, KEVIN S | reporter.nih.gov |
| Planning Grant for a Clinical Trial Of Cannabidiol For Postoperative Opioid Reduction in Primary Total Knee Arthroplasty | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $274,560 | August 2, 2021 | July 31, 2023 | BOEHNKE, KEVIN FOXMAN | reporter.nih.gov |
| Minimally Invasive On Demand Electrical Nerve Block (OD-ENB) Device for Peripheral Pain | NIH | National Institute on Drug Abuse | 2023 | $260,384 | July 1, 2023 | June 30, 2025 | VRABEC, TINA LOUISE | reporter.nih.gov |
| Peripherally Acting Analgesic for Osteoarthritis Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $259,576 | June 5, 2021 | May 31, 2023 | CHEN, RIDONG | reporter.nih.gov |
| Development of DNA-linked Matrix Metallo Protease activity probes in Osteoarthritis research | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $256,586 | September 1, 2022 | August 31, 2024 | KIM, DONGWOOK | reporter.nih.gov |
| Bone-targeted delivery of TGFβ inhibition for osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $256,486 | September 20, 2021 | August 31, 2023 | DUAN, XUCHEN AIMEE | reporter.nih.gov |
| Bayesian approaches to identify persons with osteoarthritis in electronic health records and administrative health data in the absence of a perfect reference standard | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $254,100 | March 15, 2023 | July 1, 2023 | JAFARZADEH, S. REZA | reporter.nih.gov |
| Investigating Movement-evoked Pain in osteoArthritic Conditions (IMPACT): An Observational Study to Inform Culturally-Tailored Intervention Development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $252,878 | February 1, 2020 | January 31, 2024 | BOOKER, STAJA | reporter.nih.gov |
| Predevelopment of VV8321, a Novel CRAC Channel Therapeutic for the Treatment of Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $252,039 | September 22, 2021 | March 31, 2023 | GREENBERG, MILTON L | reporter.nih.gov |
| Redesigning the Viscosupplement to Enhance the Mechanical and Biological Actions of Hyaluronic Acid | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $250,300 | September 22, 2021 | August 31, 2023 | PURCELL, BRENDAN | reporter.nih.gov |
| Novel models to study dorsal root ganglion neurons in knee osteoarthritis pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $249,000 | September 18, 2023 | July 31, 2028 | BREWER, CHELSIE L | reporter.nih.gov |
| Fibrosis, inflammation, and osteophyte formation in post-traumatic osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $249,000 | May 1, 2023 | April 30, 2028 | KNIGHTS, ALEXANDER JOHN | reporter.nih.gov |
| A new process to improve the mechanical performance of crosslinked UHMWPE injoint replacement prostheses | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 | $241,778 | September 19, 2023 | February 28, 2025 | BELLARE, ANUJ | reporter.nih.gov |
| Planning for clinical trial of fully-biologic, cell generated graft (CGEM) for ACLrepair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $238,370 | August 1, 2023 | July 31, 2025 | JAKUS, ADAM EDWARD | reporter.nih.gov |
| Quantitative Assessment of Early Metabolic and Biochemical Changes in Osteoarthritis | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $237,827 | August 1, 2019 | April 30, 2023 | KOGAN, FELIKS | reporter.nih.gov |
| Anti-catabolic drug anchored cationic exosomes for cartilage targeting and repair | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $235,500 | August 1, 2019 | May 31, 2024 | BAJPAYEE, AMBIKA GOEL | reporter.nih.gov |
| Clinical Optimization of Ultrasonic Drug Delivery Technologies for Underserved Minority US Veterans in Chronic Pain | NIH | National Institute on Minority Health and Health Disparities | 2021 | $233,597 | September 14, 2020 | May 31, 2022 | LEWIS, GEORGE KENNETH | reporter.nih.gov |
| Metabolomic Signatures of Alcohol Consumption and Risk of Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $221,866 | April 1, 2025 | February 28, 2027 | LU, BING | reporter.nih.gov |
| Muscle Geometry and its Influence on Function in Patients with Developmental Dysplasia of the Hip | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $221,690 | April 1, 2018 | June 30, 2023 | HARRIS, MICHAEL D | reporter.nih.gov |
| Novel Mechanisms Of MicroRNA-Mediated Anabolic Effects In Age-Related Osteoarthritis | NIH | National Institute on Aging | 2024 to 2025 | $221,358 | April 15, 2023 | January 31, 2028 | HSUEH, MING-FENG | reporter.nih.gov |
| Cellular and molecular mechanisms regulating synovial joint development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $219,528 | August 1, 2023 | July 31, 2026 | KIM, MINWOOK | reporter.nih.gov |
| Influence of Eccentric Exercise on Muscle and Joint Health After ACL Injury | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $218,700 | April 1, 2018 | March 31, 2023 | LEPLEY, LINDSEY K | reporter.nih.gov |
| Zero Echo Time Imaging of Knee Joint | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $217,027 | January 1, 2020 | November 30, 2022 | REGATTE, RAVINDER | reporter.nih.gov |
| The Role of gp130 Cytokines in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $217,027 | March 1, 2020 | February 28, 2023 | KIRSCH, THORSTEN | reporter.nih.gov |
| Determing the genetic basis of responses to biomechanical strain in an in vitro model of osteoarthritis | NIH | National Institute on Aging | 2021 to 2024 | $209,456 | January 1, 2021 | December 31, 2025 | HUNG, ANTHONY | reporter.nih.gov |
| SIRT1 Signaling in Injurious Chondrocyte Mechaotransduction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 | $209,220 | September 22, 2022 | August 31, 2024 | WAGNER, DIANE | reporter.nih.gov |
| Fibrosis, inflammation, and osteophyte formation in post-traumatic osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $206,160 | May 1, 2023 | April 30, 2025 | KNIGHTS, ALEXANDER JOHN | reporter.nih.gov |
| MRI Predictors of Outcome after Arthroscopic Partial Meniscectomy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $206,144 | August 1, 2019 | July 31, 2022 | SUBHAS, NAVEEN | reporter.nih.gov |
| Glycans in joint disease and glycosylated lubricin mimetics for osteoarthritis therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $204,434 | July 10, 2017 | June 30, 2023 | REESINK, HEIDI | reporter.nih.gov |
| Preventing Incident Knee Osteoarthritis: The Osteoarthritis Prevention Study (TOPS) | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $203,920 | April 1, 2020 | March 31, 2023 | MESSIER, STEPHEN P | reporter.nih.gov |
| Developing the common marmoset as a translational model of age-related osteoarthritis | NIH | National Institute on Aging | 2021 | $199,124 | September 30, 2020 | May 31, 2023 | KONOPKA, ADAM R | reporter.nih.gov |
| The Multiscale Role of Piezo Channels in Obesity-Associated Cartilage Damage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $191,678 | April 1, 2022 | March 31, 2026 | ELY, ERICA VALENTINE | reporter.nih.gov |
| Establishing a new genetic mouse model of osteoarthritis | NIH | National Institute on Aging | 2021 | $190,625 | September 11, 2020 | May 31, 2023 | GRUNWALD, DAVID J. | reporter.nih.gov |
| VietAmerican Health Pilot Study | NIH | National Institute on Minority Health and Health Disparities | 2021 | $186,291 | July 25, 2020 | August 31, 2023 | NGUYEN, UYEN-SA DUC TRAN | reporter.nih.gov |
| The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $180,942 | February 1, 2017 | June 30, 2024 | NEOGI, TUHINA | reporter.nih.gov |
| The Role of Hyaluronan Interactions with CD44 and RHAMM in Cartilage Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $180,856 | February 1, 2020 | November 30, 2023 | KIRSCH, THORSTEN | reporter.nih.gov |
| Roles of the superficial zone in mature articular cartilage | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2023 | $180,036 | September 14, 2022 | October 31, 2023 | RUX, DANIELLE RENAE | reporter.nih.gov |
| Racial disparities in total joint arthroplasty (TJA) recovery | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $178,722 | September 10, 2020 | July 31, 2023 | LIU, SHAO-HSIEN | reporter.nih.gov |
| A PILOT RANDOMIZED CONTROLLED TRIAL OF HAND TRACTION FOR NODAL OSTEOARTHRITIS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $173,408 | January 15, 2019 | November 30, 2023 | LO, GRACE | reporter.nih.gov |
| Risk factors for anterior knee pain and the relation to future patellofemoral osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $172,910 | September 1, 2021 | December 31, 2024 | STEFANIK, JOSHUA JON | reporter.nih.gov |
| Facilitating meniscus healing through SDF-1/CXCR4 axis modified cell-therapy | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $171,787 | April 1, 2020 | March 31, 2023 | JAYASURIYA, CHATHURAKA TEEKSHANA | reporter.nih.gov |
| Optimizing a dyadic physical activity intervention for Hispanics with osteoarthritis and their physical activity supporter | NIH | National Institute on Minority Health and Health Disparities | 2021 to 2022 | $169,984 | July 30, 2020 | September 30, 2023 | SOTO, SANDRA HYATT | reporter.nih.gov |
| CK2.1, a novel peptide for cartilage repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $168,970 | September 14, 2020 | July 31, 2023 | NOHE, ANJA G | reporter.nih.gov |
| Targeting MicroRNAs for Osteochondral Tissue Engineering | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $168,052 | May 1, 2020 | April 30, 2023 | MCALINDEN, AUDREY | reporter.nih.gov |
| Three-Dimensional UTE Magnetic Resonance Imaging of the Osteochondral Junction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $168,052 | July 1, 2020 | June 30, 2023 | MA, YAJUN | reporter.nih.gov |
| Comparative effectiveness of mind-body interventions for osteoarthritis - individual patient data network meta-analysis | NIH | National Center for Complementary & Integrative Health | 2021 | $167,400 | March 1, 2017 | February 28, 2022 | BANNURU, RAVEENDHARA REDDY | reporter.nih.gov |
| The Effects of Reduced ACL Stiffness on Dynamic In Vivo Joint Function | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $167,265 | July 19, 2019 | October 21, 2022 | BEVERIDGE, JILLIAN ELIZABETH | reporter.nih.gov |
| Osteoarthritis After ACL Injury: Establishing Cumulative Joint Loading as a Preventative Target | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $166,954 | February 25, 2020 | January 31, 2023 | WELLSANDT, ELIZABETH A | reporter.nih.gov |
| The Relation of Altered Pain Processing to Impact Loading and Response to a Gait Retraining Treatment in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $165,564 | June 1, 2018 | October 31, 2023 | STEFANIK, JOSHUA JON | reporter.nih.gov |
| Notch Signaling in the Regulation of TMJ Osteoarthritis | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2022 | $164,001 | September 1, 2021 | March 5, 2023 | YADAV, SUMIT | reporter.nih.gov |
| Evaluating the relationship between immune checkpoint inhibitors and osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $163,750 | January 10, 2023 | December 31, 2025 | CAPPELLI, LAURA CHRISTINE | reporter.nih.gov |
| Application of advanced methodology to osteoarthritis phenotyping | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $160,567 | January 15, 2020 | November 30, 2021 | NELSON, AMANDA E | reporter.nih.gov |
| An integrative study of circulating leukocyte composition, epigenetic patterns, and functional consequences in knee osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $158,981 | August 1, 2020 | May 31, 2022 | JEFFRIES, MATLOCK | reporter.nih.gov |
| SIRT6 as a novel therapeutic target in aging and age-related osteoarthritis | NIH | National Institute on Aging | 2021 to 2022 | $156,000 | September 30, 2021 | November 30, 2023 | COLLINS, JOHN A | reporter.nih.gov |
| Circadian Clock Disruption as a Novel Mechanism to Influence Osteoarthritis Risk in Aging Populations | NIH | National Institute on Aging | 2025 | $155,500 | August 1, 2025 | July 31, 2027 | ROWLANDS, ELIZABETH YANIK | reporter.nih.gov |
| The Role of Inflammation in Knee Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $154,873 | April 1, 2022 | March 31, 2027 | MACFARLANE, LINDSEY A. | reporter.nih.gov |
| A Novel Strategy of Endogenous Progenitor Cell Homing Using Exosomes for Condylar Fibrocartilage Repair in Temporomandibular Joint | NIH | National Institute of Dental & Craniofacial Research | 2021 | $154,500 | September 10, 2020 | August 31, 2023 | SHIN, KYUNGSUP | reporter.nih.gov |
| Multiscale mechano-metabolic regulation of fibrous tissue homeostasis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $149,348 | September 1, 2024 | August 31, 2027 | KUPRATIS, MEGHAN ELIZABETH | reporter.nih.gov |
| Enhanced cartilage formation of chondrocytes in viscoelastic ECMs under mechanical loading | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $148,880 | May 7, 2024 | July 6, 2027 | SONG, HYUK JOON JAKE | reporter.nih.gov |
| Cellular and molecular mechanisms regulating synovial joint development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $146,352 | August 1, 2021 | May 1, 2023 | KIM, MINWOOK | reporter.nih.gov |
| Novel mechanisms of microRNA-mediated anabolic effects in age-related osteoarthritis | NIH | National Institute on Aging | 2023 to 2024 | $142,998 | April 15, 2023 | March 31, 2024 | HSUEH, MING-FENG | reporter.nih.gov |
| The Impact of COL6A3 Mutation on Inflammatory Susceptibility in Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2024 | $142,140 | April 1, 2022 | March 31, 2025 | HARISSA, ZAINAB | reporter.nih.gov |
| Injectable Fibrous Scaffolds for Meniscal Repair | NIH | National Institute on Aging | 2021 to 2023 | $137,831 | September 1, 2021 | August 31, 2024 | XU, KAREN | reporter.nih.gov |
| Pre-Clinical Development of an Instrumented Trapezium Carpal Bone | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $137,429 | April 1, 2020 | March 31, 2023 | CRISCO, JOSEPH J | reporter.nih.gov |
| Ultrahigh-Field MRI of Hip Joint Diseases Leading to Early Osteoarthritis | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $129,897 | September 1, 2017 | November 30, 2022 | JOHNSON, CASEY PETER | reporter.nih.gov |
| Simulation framework to develop ankle exoskeleton gait assistance for older adults | NIH | National Institute on Aging | 2021 | $128,574 | April 1, 2020 | January 3, 2022 | SONG, SEUNGMOON | reporter.nih.gov |
| Targeting GPR68 as a novel modulator of osteoarthritis | NIH | National Center for Advancing Translational Sciences | 2022 | $128,200 | July 1, 2022 | June 30, 2024 | KHAN, MOHD NAZIR | reporter.nih.gov |
| Using metabolomics to identify novel biomarkers for knee osteoarthritis risk | NIH | National Institute on Aging | 2021 | $127,628 | March 1, 2017 | February 28, 2022 | KARVONEN-GUTIERREZ, CARRIE ANNE | reporter.nih.gov |
| Role of gut microbiome dysbiosis and sustained inflammation in osteoarthritis | NIH | Office of the Director, National Institutes of Health | 2025 | $124,794 | August 1, 2025 | July 31, 2029 | PEZZANITE, LYNN | reporter.nih.gov |
| Mind Your Walk Intervention for Community-Based Management of Knee OA: A Feasibility Study | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 | $124,463 | September 6, 2017 | July 31, 2022 | KUMAR, DEEPAK | reporter.nih.gov |
| WISP3 and Progressive Pseudorheumatoid Arthropathy of Childhood | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 | $122,284 | September 16, 2024 | August 31, 2025 | CRAFT, APRIL MARIE | reporter.nih.gov |
| eQTL mapping in response to osteoarthritis induction in differentiated skeletal cell types | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $117,034 | June 1, 2020 | January 8, 2023 | HOUSMAN, GENEVIEVE | reporter.nih.gov |
| Assessing scaphotrapeziotrapezoid arthrokinematics using 4DCT | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $115,522 | July 1, 2023 | July 2, 2025 | TRENTADUE, TAYLOR PATRICIA | reporter.nih.gov |
| Form-Function Relationships in Femoroacetabular Impingement Syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2022 | $110,753 | August 17, 2020 | March 10, 2023 | MOZINGO, JOSEPH | reporter.nih.gov |
| Articular Microbiome for Prediction and Potential Therapy of Periprosthetic Joint Infections | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $104,732 | August 5, 2025 | July 31, 2027 | SZYMCZAK, ALEKSANDER M | reporter.nih.gov |
| Molecular control of chondrocyte hypertrophy: an evolutionary approach | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2024 | $104,572 | September 1, 2023 | January 6, 2025 | PALMER, MICHAEL | reporter.nih.gov |
| Novel transcriptional regulators of synovial joint and bone development | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $98,512 | April 1, 2024 | March 31, 2026 | ONGGO, SHARON | reporter.nih.gov |
| Testing Miniature Knee Joint System as a New Tool to Study Neuroimmune Interactions in Osteoarthritis Pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $98,512 | August 1, 2024 | July 31, 2026 | MAKARCZYK, MEAGAN JOANNE | reporter.nih.gov |
| The impact of TLR signaling on osteoclast-mediated bone remodeling and inflammation in osteoarthritis. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $98,512 | August 1, 2024 | July 31, 2027 | MURPHY, LANCE AVERY | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| University of Florida | Gainesville, FL | 19 | $31.3 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 6 | $25 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 9 | $22.7 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 11 | $21.2 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 27 | $19.4 million | 0 | $0 |
| Stanford University | Stanford, CA | 16 | $18.8 million | 0 | $0 |
| Washington University | Saint Louis, MO | 23 | $17.7 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 14 | $17.6 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 18 | $15.2 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 10 | $14.7 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 11 | $14.1 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 10 | $12.3 million | 0 | $0 |
| Zetroz Systems, LLC | Trumbull, CT | 3 | $12.2 million | 0 | $0 |
| Univ of Arkansas for Med Scis | Little Rock, AR | 1 | $11.7 million | 0 | $0 |
| Duke University | Durham, NC | 10 | $11.5 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 2 | $11 million | 0 | $0 |
| Wake Forest University | Winston Salem, NC | 4 | $10.9 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 14 | $10.5 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 8 | $9.7 million | 0 | $0 |
| Tufts Medical Center | Boston, MA | 6 | $9.2 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 7 | $8.6 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 8 | $8.3 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 9 | $6.9 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 4 | $6.8 million | 0 | $0 |
| University of Rochester | Rochester, NY | 6 | $6.7 million | 0 | $0 |
| Trustees of Boston University | Boston, MA | 7 | $6.6 million | 0 | $0 |
| University of California at Davis | Davis, CA | 3 | $6.6 million | 0 | $0 |
| Scripps Research Institute, the | La Jolla, CA | 4 | $6.6 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 6 | $6.4 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 9 | $6.1 million | 0 | $0 |
| Rhode Island Hospital | Providence, RI | 8 | $5.6 million | 0 | $0 |
| University of Colorado at Boulder | Boulder, CO | 3 | $5.4 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 3 | $5.4 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 4 | $5.4 million | 0 | $0 |
| North Carolina State University | Raleigh, NC | 2 | $5.3 million | 0 | $0 |
| Oklahoma Medical Research Foundation | Oklahoma City, OK | 6 | $5.1 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 6 | $5.1 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 4 | $4.9 million | 0 | $0 |
| Harvard Medical School | Boston, MA | 2 | $4.7 million | 0 | $0 |
| Tufts University Boston | Boston, MA | 4 | $4.7 million | 0 | $0 |
| University of Delaware | Newark, DE | 7 | $4.7 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 3 | $4.7 million | 0 | $0 |
| George Mason University | Fairfax, VA | 1 | $4.6 million | 0 | $0 |
| Steadman Philippon Research Institute | Vail, CO | 3 | $4.6 million | 0 | $0 |
| Cytex Therapeutics Inc. | Durham, NC | 4 | $4.2 million | 0 | $0 |
| Dorian Therapeutics, Inc. | San Carlos, CA | 1 | $4.2 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 4 | $4 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 5 | $3.9 million | 0 | $0 |
| University of Connecticut | Storrs, CT | 5 | $3.7 million | 0 | $0 |
| Thomas Jefferson University | Philadelphia, PA | 3 | $3.7 million | 0 | $0 |
| Northeastern University | Boston, MA | 5 | $3.4 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 4 | $3.4 million | 0 | $0 |
| University of Connecticut SCH of Med/dnt | Farmington, CT | 7 | $3.3 million | 0 | $0 |
| Van Andel Research Institute | Grand Rapids, MI | 2 | $3.3 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 3 | $3.1 million | 0 | $0 |
| Drexel University | Philadelphia, PA | 3 | $3.1 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 3 | $3.1 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 7 | $3 million | 0 | $0 |
| Montana State University | Bozeman, MT | 2 | $2.9 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 4 | $2.9 million | 0 | $0 |
| University of Vermont & ST Agric College | Burlington, VT | 3 | $2.6 million | 0 | $0 |
| Columbia University | New York, NY | 3 | $2.6 million | 0 | $0 |
| Ohio University | Athens, OH | 3 | $2.5 million | 0 | $0 |
| Spaulding Rehabilitation Hospital | Charlestown, MA | 4 | $2.5 million | 0 | $0 |
| Regenosine INC | Princeton, NJ | 2 | $2.5 million | 0 | $0 |
| University of Nebraska Medical Center | Omaha, NE | 3 | $2.4 million | 0 | $0 |
| William Marsh Rice University | Houston, TX | 1 | $2.4 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 2 | $2.3 million | 0 | $0 |
| Saint Louis University | Saint Louis, MO | 2 | $2.2 million | 0 | $0 |
| Carnegie Mellon University | Pittsburgh, PA | 1 | $2.2 million | 0 | $0 |
| Palo Alto Veterans Instit for Research | Palo Alto, CA | 1 | $2.1 million | 0 | $0 |
| Brixton Biosciences, Inc. | Cambridge, MA | 1 | $2 million | 0 | $0 |
| Altec, Inc. | Natick, MA | 1 | $2 million | 0 | $0 |
| Harvard University | Cambridge, MA | 2 | $1.9 million | 0 | $0 |
| Barron Associates, Inc. | Charlottesville, VA | 1 | $1.8 million | 0 | $0 |
| Cornell University | Ithaca, NY | 5 | $1.8 million | 0 | $0 |
| CFD Research Corporation | Huntsville, AL | 1 | $1.7 million | 0 | $0 |
| Ensign Pharmaceutical, INC | Omaha, NE | 1 | $1.7 million | 0 | $0 |
| University of Washington | Seattle, WA | 1 | $1.7 million | 0 | $0 |
| Neuromuscular Dynamics, LLC | La Crescenta, CA | 1 | $1.6 million | 0 | $0 |
| Georgia State University | Atlanta, GA | 1 | $1.6 million | 0 | $0 |
| Syntr Health Technologies, LLC | Irvine, CA | 2 | $1.5 million | 0 | $0 |
| Texas A&M Engineering Experiment Station | College Station, TX | 1 | $1.4 million | 0 | $0 |
| Yale University | New Haven, CT | 1 | $1.4 million | 0 | $0 |
| WNT Scientific, LLC | Rochester, NY | 3 | $1.3 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 2 | $1.3 million | 0 | $0 |
| Novopedics, Inc. | Princeton, NJ | 2 | $1.3 million | 0 | $0 |
| Hospital for Special Surgery | New York, NY | 1 | $1.3 million | 0 | $0 |
| Tulane University of Louisiana | New Orleans, LA | 1 | $1.3 million | 0 | $0 |
| Emory University | Atlanta, GA | 3 | $1.2 million | 0 | $0 |
| Seattle Inst for Biomedical/clinical Res | Seattle, WA | 1 | $1.1 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 2 | $1 million | 0 | $0 |
| Pennsylvania State Univ Hershey Med CTR | Hershey, PA | 1 | $998,289 | 0 | $0 |
| Florida State University | Tallahassee, FL | 1 | $973,809 | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 2 | $935,455 | 0 | $0 |
| University of Chicago | Chicago, IL | 3 | $929,251 | 0 | $0 |
| Villanova University | Villanova, PA | 1 | $927,833 | 0 | $0 |
| University of Kansas Medical Center | Kansas City, KS | 1 | $900,405 | 0 | $0 |
| Hebrew Rehabilitation Center for Aged | Boston, MA | 1 | $842,622 | 0 | $0 |
| Oakland University | Rochester, MI | 1 | $824,998 | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 230 | $133,407,516 | 0 | $0 |
| 2024 | 243 | $118,172,525 | 0 | $0 |
| 2023 | 244 | $112,551,929 | 0 | $0 |
| 2022 | 242 | $117,783,719 | 0 | $0 |
| 2021 | 233 | $116,038,167 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.