Data / Research funding / Nanotechnology
Nanotechnology: 2,662 NIH awards ($2.9B) to 587 organizations
2,662 NIH awards ($2.9B) in the NIH spending category Nanotechnology, to 587 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.
- Topic
- NIH spending category
Awards
The 500 largest of 2,662 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $29,083,069 | August 16, 2021 | April 30, 2027 | MONTANER, LUIS J | reporter.nih.gov |
| RADX-TECH - LUMINOSTICS, INC. SMARTPHONE-BASED TEST FOR RAPID SARS-COV-2 ANTIGEN DETECTION FROM NASAL SWABS | NIH | National Heart, Lung, and Blood Institute | 2021 | $28,624,460 | September 30, 2020 | September 29, 2021 | RAJA, BALA | reporter.nih.gov |
| Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS). | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $22,785,879 | September 25, 2023 | August 31, 2027 | ANDREWS, JINSY | reporter.nih.gov |
| Guide RNA manufacturing capabilities for platform in vivo base editing therapies for metabolic liver diseases | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $17,556,074 | August 1, 2023 | July 31, 2028 | PERANTEAU, WILLIAM H. | reporter.nih.gov |
| Strategies for targeting astrocyte reactivity in Alzheimer's disease and related dementias | NIH | National Institute on Aging | 2022 to 2025 | $17,073,728 | September 1, 2022 | June 30, 2027 | NORRIS, CHRISTOPHER MARK | reporter.nih.gov |
| Discovery of Chemical Probes and Therapeutic Leads, Phase II | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $12,886,039 | September 1, 2014 | June 30, 2026 | FOX, JOSEPH M | reporter.nih.gov |
| The Kansas Institute for Precision Medicine | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $11,932,398 | February 15, 2019 | March 31, 2029 | GODWIN, ANDREW K. | reporter.nih.gov |
| Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS). | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $11,639,047 | September 25, 2023 | August 31, 2027 | ANDREWS, JINSY | reporter.nih.gov |
| cGMP Manufacture, Fill-Finish, Release, Analytical and Stability Testing and Stability Program of a Nanoparticle Based HIV Envelope Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $8,013,603 | August 30, 2022 | August 29, 2030 | HASSELL, THOMAS | reporter.nih.gov |
| Restoring Vision with High-Fidelity Nonsense Codon Correction | NIH | National Eye Institute | 2021 to 2025 | $7,812,597 | February 1, 2021 | November 30, 2026 | PATTNAIK, BIKASH RANJAN | reporter.nih.gov |
| I. Institutional Career Development Core | NIH | National Center for Advancing Translational Sciences | 2021 to 2025 | $7,643,843 | September 5, 2017 | June 30, 2027 | ZHU, YUAN-SHAN | reporter.nih.gov |
| ADVANCED DEVELOPMENT OF LQ A LIPOSOME-BASED SAPONIN-CONTAINING ADJUVANT FOR USE IN PANSARBECOVIRUS VACCINES | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $6,937,118 | September 30, 2023 | September 29, 2026 | COLLINS, NICOLAS | reporter.nih.gov |
| An Intranasal GDNF Gene Therapy for Opioid Relapse Reduction | NIH | National Institute on Drug Abuse | 2021 | $6,693,512 | September 15, 2021 | August 31, 2025 | WASZCZAK, BARBARA LEE | reporter.nih.gov |
| Integrated Epithelial and Muscosal Biology | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $6,598,874 | September 1, 1997 | June 16, 2026 | LENCER, WAYNE I | reporter.nih.gov |
| Understanding how membrane composition directs membrane protein structure and function | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $6,273,175 | June 1, 2023 | May 31, 2028 | FERGUSON, KATHRYN M | reporter.nih.gov |
| BASE TITLE: PREVENT PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY AND INTERMEDIATE ENDPOINT BIOMAKERSTASK ORDER TITLE: VACCINES AGAINST FUSOBACTERIUM FOR FAP-AND LYNCH SYNDROME-ASSOCIA | NIH | National Cancer Institute | 2022 to 2024 | $6,227,249 | June 15, 2022 | May 15, 2025 | CLAPPER, MARGIE L. | reporter.nih.gov |
| Clinical Translation of Ultrasonic Ketamine Uncaging for Non-Opioid Therapy of Chronic Pain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $6,205,798 | September 30, 2019 | May 31, 2026 | AIRAN, RAAG D | reporter.nih.gov |
| Design and testing of immunogens to elicit 10E8-like broadly neutralizing antibodies against HIV | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $6,090,710 | July 8, 2019 | August 31, 2029 | SCHIFFNER, TORBEN | reporter.nih.gov |
| Next-generation spatial -omics: High-throughput, single-molecule proteomic imaging with subcellular resolution | NIH | National Institute of Mental Health | 2023 to 2024 | $5,926,670 | September 18, 2023 | July 31, 2028 | ROUKES, MICHAEL L | reporter.nih.gov |
| Rational design and efficacy testing of vaccines against HCV | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $5,737,237 | May 5, 2022 | April 30, 2027 | FUERST, THOMAS R | reporter.nih.gov |
| Fusion of nanomagnetic and viral tools to interrogate brain-body circuits | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $5,298,216 | September 30, 2021 | July 31, 2026 | ANIKEEVA, POLINA O | reporter.nih.gov |
| The RNA nanomachines of gene expression dissected at the single molecule level | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $4,907,582 | May 1, 2019 | April 30, 2029 | WALTER, NILS G | reporter.nih.gov |
| Strategically Engineered Multi-Antigen KSHV Vaccine: Integrating Humoral and Cellular Immunity for Effective Protection | NIH | National Cancer Institute | 2025 | $4,857,475 | August 7, 2025 | July 31, 2029 | WU, TING-TING | reporter.nih.gov |
| Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,835,728 | December 1, 2020 | November 30, 2026 | ADAMS, JOHN H | reporter.nih.gov |
| Endosomal mechanisms signaling oral cancer pain | NIH | National Institute of Dental & Craniofacial Research | 2023 | $4,820,611 | September 19, 2023 | August 31, 2026 | SCHMIDT, BRIAN L | reporter.nih.gov |
| Center for Sub-Cellular Genomics | NIH | National Human Genome Research Institute | 2021 to 2022 | $4,500,000 | September 1, 2018 | June 30, 2024 | KIM, JUNHYONG | reporter.nih.gov |
| Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $4,459,174 | June 1, 2022 | May 31, 2027 | GRATTONI, ALESSANDRO | reporter.nih.gov |
| Alleviation of ER stress as a translational strategy to curb ocular viral infections | NIH | National Eye Institute | 2022 to 2025 | $4,325,995 | March 1, 2022 | December 31, 2026 | SHUKLA, DEEPAK | reporter.nih.gov |
| Structure-function studies of the membrane-interacting domains of HIV-1 Env spike | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,299,010 | May 20, 2016 | June 30, 2027 | CHEN, BING | reporter.nih.gov |
| The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,208,331 | June 1, 2020 | July 31, 2030 | SESHADRI, CHETAN | reporter.nih.gov |
| CD11b: A Novel Alternate Receptor for CD154 during Alloimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,188,152 | March 17, 2020 | June 30, 2029 | FORD, MANDY L | reporter.nih.gov |
| Development of an oral liver-targeted prime-and-trap malaria vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,104,491 | December 1, 2020 | November 30, 2026 | MURPHY, SEAN C | reporter.nih.gov |
| NextGen Long-acting and targeted combination ART for Children with HIV | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $4,058,459 | April 6, 2020 | March 31, 2027 | HO, RODNEY J.Y. | reporter.nih.gov |
| Nucleoside-modified mRNA vaccine for prevention and treatment of genital herpes | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,009,506 | April 15, 2019 | June 30, 2027 | FRIEDMAN, HARVEY MICHAEL | reporter.nih.gov |
| Quantifying Physiologic and Pathologic Viscoelastic Phases of Biomolecular Condensates by Correlative Force and Fluorescence Microscopy | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,975,375 | August 15, 2020 | August 31, 2029 | BANERJEE, PRIYA R. | reporter.nih.gov |
| RADX TECH - CERES NANOSCIENCE INC NANOTRAP PARTICLE MANUFACTURING | NIH | National Heart, Lung, and Blood Institute | 2021 | $3,974,000 | August 28, 2020 | May 31, 2021 | DUNLAP, ROSS | reporter.nih.gov |
| Systemic regulation of metastasis | NIH | National Cancer Institute | 2021 to 2024 | $3,947,638 | September 18, 2018 | August 31, 2025 | LYDEN, DAVID CHARLES | reporter.nih.gov |
| Next-generation spatial -omics: High-throughput, single-molecule proteomic imaging with subcellular resolution | NIH | National Institute of Mental Health | 2025 | $3,918,707 | September 18, 2023 | July 31, 2028 | ROUKES, MICHAEL L | reporter.nih.gov |
| Discovery of Adjuvants for mRNA Vaccines | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $3,882,045 | September 30, 2025 | September 29, 2026 | CARSON, DENNIS | reporter.nih.gov |
| The Epitranscriptome as a Novel Mechanism of Arsenic-Induced Diabetes. | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $3,858,238 | January 1, 2021 | October 31, 2026 | NAVAS-ACIEN, ANA | reporter.nih.gov |
| Engineering biophysical microtechnologies for hematologic applications in health and disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,836,413 | March 22, 2019 | February 28, 2027 | LAM, WILBUR A | reporter.nih.gov |
| Clinical Translation of Targeted and Noninvasive Ultrasonic Propofol Uncaging | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $3,833,148 | January 1, 2021 | December 31, 2025 | AIRAN, RAAG D | reporter.nih.gov |
| SCGE Disease Models Studies Supplement: Development of LNP-mediated based editing to treat Leber Congenital Amaurosis (LCA) for vision restoration in mouse model | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $3,783,475 | September 18, 2018 | July 31, 2023 | CHEN, ZHENG-YI | reporter.nih.gov |
| Managing Atherosclerosis by Modulating HDL Function | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,778,414 | June 1, 2013 | March 31, 2026 | GHADIRI, M. REZA | reporter.nih.gov |
| Structure-based design of broad flavivirus immunogens | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,710,975 | September 24, 2021 | August 31, 2026 | LAI, JONATHAN R. | reporter.nih.gov |
| Targeting Cell-Type Specific Disease Phenotypes to Promote CNS Repair | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,654,519 | August 1, 2023 | April 30, 2028 | LEE, JAE K | reporter.nih.gov |
| Immunovascular interactions in postoperative delirium superimposed on dementia (DSD). | NIH | National Institute on Aging | 2022 to 2025 | $3,624,866 | September 15, 2022 | August 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Ultrasensitive HIV viral load quantitation using designer DNA nanostructure capture probes and photonic resonator interference scattering microscopy | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,622,822 | January 21, 2021 | December 31, 2026 | DEMIRCI, UTKAN | reporter.nih.gov |
| Synthetic Nanoparticle-antibody (SNAb) Based Depletion of Myeloid-Derived Suppressor Cells for TB Host-Directed Therapy | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $3,610,454 | August 5, 2021 | July 31, 2025 | RENGARAJAN, JYOTHI | reporter.nih.gov |
| Biofilm Elimination and Caries Prevention using Multifunctional Nanocatalysts | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $3,608,276 | December 9, 2016 | August 31, 2027 | KOO, HYUN | reporter.nih.gov |
| Nanoscale Approaches to Understanding Membrane Protein Function | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,593,835 | June 1, 2016 | June 7, 2026 | SLIGAR, STEPHEN G. | reporter.nih.gov |
| Internal Dynamics of the Postsynaptic Density | NIH | National Institute of Mental Health | 2021 to 2025 | $3,583,009 | November 18, 2024 | October 31, 2029 | BLANPIED, THOMAS A | reporter.nih.gov |
| Effects of CSF1R Blockade on Repopulation of SIV Reservoirs from the CNS to the Periphery After Antiretroviral Therapy Interruption | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,573,272 | July 15, 2021 | June 30, 2027 | WILLIAMS, KENNETH C | reporter.nih.gov |
| Transforming HIV vaccine design with a hybrid technology that leverages features of mRNA and protein nanoparticle platforms | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $3,559,750 | September 26, 2025 | August 31, 2029 | HOFFMANN, MAGNUS ADRIAN GERO | reporter.nih.gov |
| Combination nanovaccine-based immunization against influenza virus in the aged: immunity and protection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,518,508 | February 16, 2021 | January 31, 2027 | KOHUT, MARIAN L | reporter.nih.gov |
| LASER ART for PreP | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,504,782 | April 12, 2021 | March 31, 2027 | GENDELMAN, HOWARD E | reporter.nih.gov |
| A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,481,044 | September 17, 2021 | August 31, 2026 | XIONG, YONG | reporter.nih.gov |
| Maximizing flexibility: Optimized neural probes and electronics for long term, high bandwidth recordings | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $3,464,638 | September 1, 2020 | July 31, 2025 | XIE, CHONG | reporter.nih.gov |
| HIV-1DetectionandEliminationFrom CNS Mononuclear Phagocytes | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,451,500 | August 1, 2021 | June 30, 2027 | GORANTLA, SANTHI | reporter.nih.gov |
| High Accuracy Nanopore Sequencing. | NIH | National Human Genome Research Institute | 2021 to 2024 | $3,428,907 | September 23, 2009 | November 30, 2025 | GUNDLACH, JENS | reporter.nih.gov |
| Prolonged duration and triggered local anesthesia | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,405,757 | May 1, 2019 | May 31, 2029 | KOHANE, DANIEL S | reporter.nih.gov |
| Extracellular Vesicle Proteomic Fingerprinting of Ovarian Cancer for Early Detection with a Nanoengineered Microsystem | NIH | National Cancer Institute | 2021 to 2025 | $3,402,215 | April 1, 2021 | March 31, 2026 | GODWIN, ANDREW K. | reporter.nih.gov |
| Nanoscale probes for sensing molecular functions in live cells | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,364,334 | June 1, 2021 | May 31, 2027 | CUI, BIANXIAO | reporter.nih.gov |
| Support for Registration Enabling Phase 3 Clinical Trial for Nanotechnology-Based Treatment of Carcinoma in Situ of the Oral Cavity (Stage 0 Oral Cancer) | NIH | National Cancer Institute | 2024 to 2025 | $3,329,707 | June 14, 2024 | May 31, 2027 | GOLDBERG, MANIJEH N | reporter.nih.gov |
| Leveraging 3D bioprinted organoid constructs to pattern and model human brain development | NIH | National Institute of Mental Health | 2021 to 2025 | $3,321,612 | April 1, 2021 | January 31, 2026 | SLOAN, STEVEN A | reporter.nih.gov |
| SARS-CoV-2 vaccines based on RBDs with engineered glycosylation sites | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,300,000 | August 17, 2023 | July 31, 2026 | ALPERT, MICHAEL DAVID | reporter.nih.gov |
| Theranostics for Pediatric Brain Cancer | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,299,320 | April 15, 2021 | January 31, 2027 | DALDRUP-LINK, HEIKE ELIZABETH | reporter.nih.gov |
| Gene editing in the brain with CRISPR-PEG | NIH | National Institute of Mental Health | 2021 to 2025 | $3,288,527 | April 1, 2021 | January 31, 2027 | LEE, HYE YOUNG | reporter.nih.gov |
| Nanomedicine approaches for prevention of inflammation-induced preterm birth | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,286,557 | April 13, 2021 | March 31, 2026 | ENSIGN, LAURA | reporter.nih.gov |
| A smartphone-enabled point-of-care HCV Ag diagnostic using catalytic nanoparticles and AI-enhanced image processing | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $3,284,055 | September 9, 2022 | June 30, 2027 | SHAFIEE, HADI | reporter.nih.gov |
| Low-Dose Magneto-Thrombolysis to Expand Stroke Care | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $3,263,292 | July 1, 2023 | June 30, 2026 | CREIGHTON, FRANCIS MILTON | reporter.nih.gov |
| Nanoscale programing of celluar and physiological phenotypes | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,246,554 | January 1, 2020 | June 30, 2025 | DOKHOLYAN, NIKOLAY | reporter.nih.gov |
| A novel Lyme disease vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,240,479 | June 7, 2022 | May 31, 2027 | FIKRIG, EROL | reporter.nih.gov |
| Novel nanoparticulate adjuvants to enhance HIV-1 Env specific mucosal antibody responses | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $3,234,356 | July 3, 2019 | June 30, 2025 | KASTURI, SUDHIR PAI | reporter.nih.gov |
| Imaging Modulation of Immune Phenotype | NIH | National Cancer Institute | 2021 to 2025 | $3,227,270 | February 1, 2021 | January 31, 2027 | FERRARA, KATHERINE W | reporter.nih.gov |
| Targeting innate immunity for induction of robust renal allograft tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,224,166 | July 25, 2023 | April 30, 2028 | KAWAI, TATSUO | reporter.nih.gov |
| Precision nanomedicine targeting novel endothelial mechano-sensing mechanisms | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,222,128 | June 1, 2022 | May 31, 2029 | FANG, YUN | reporter.nih.gov |
| Miniaturized silicon neurochemical probe to monitor brain chemistry | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $3,219,130 | May 3, 2022 | April 30, 2026 | VLASOV, YURII | reporter.nih.gov |
| Addressing Chemoresistance in Pancreatic and Ovarian Cancers: Photodynamic Priming and Repurposing of Tetracyclines using Targeted Photo-Activable Multi-Inhibitor Liposome | NIH | National Cancer Institute | 2021 to 2025 | $3,218,280 | April 1, 2021 | March 31, 2027 | HUANG, HUANG CHIAO | reporter.nih.gov |
| A versatile structure-based therapeutic platform for development of VHH-based antitoxin and antiviral agents | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,217,894 | August 4, 2023 | July 31, 2027 | SHOEMAKER, CHARLES BIX | reporter.nih.gov |
| Co-Clinical Research Resource for Imaging Tumor Associated Macrophages | NIH | National Cancer Institute | 2021 to 2025 | $3,191,659 | September 15, 2021 | August 31, 2026 | DALDRUP-LINK, HEIKE ELIZABETH | reporter.nih.gov |
| Targeted Gene Delivery Systems Treating Lung Diseases | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,172,072 | June 15, 2022 | May 31, 2026 | TIRRELL, MATTHEW | reporter.nih.gov |
| Precision magnetic hyperthermia by integrating magnetic particle imaging | NIH | National Cancer Institute | 2021 to 2025 | $3,163,595 | July 1, 2021 | June 30, 2027 | BULTE, JEFF W. | reporter.nih.gov |
| Immunotherapy via engineered therapeutic programs in tumors using RNA | NIH | National Cancer Institute | 2021 to 2025 | $3,154,064 | September 20, 2021 | August 31, 2027 | WEISS, RON | reporter.nih.gov |
| Enzymeless, controlled electrostatic ratcheting in solid-state nanopores | NIH | National Human Genome Research Institute | 2022 to 2025 | $3,143,754 | August 15, 2022 | June 30, 2027 | SHEPARD, KENNETH L | reporter.nih.gov |
| CD4+ T cells and neoantigens in melanoma immunotherapy. | NIH | National Cancer Institute | 2021 to 2025 | $3,143,740 | December 1, 2020 | November 30, 2026 | WANG, RONGFU | reporter.nih.gov |
| Allergen Loaded Nanoparticles for Food Allergy Tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $3,140,831 | September 16, 2020 | August 31, 2025 | SHEA, LONNIE D | reporter.nih.gov |
| The role of signaling adaptor protein epsin in atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,138,613 | December 15, 2020 | November 30, 2025 | CHEN, HONG | reporter.nih.gov |
| Targeted immune therapies in heart transplantation | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $3,118,293 | February 1, 2023 | January 31, 2026 | ABDI, REZA | reporter.nih.gov |
| Universal room temperature stable influenza nanovaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $3,103,165 | January 24, 2019 | December 31, 2024 | NARASIMHAN, BALAJI | reporter.nih.gov |
| Vascular Targeting of Nanocarriers for RNA | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,088,329 | February 5, 2021 | January 31, 2026 | MUZYKANTOV, VLADIMIR R | reporter.nih.gov |
| Engineered metabolite-based nanoparticles for immunomodulation of macrophages to treat obesity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $3,065,252 | September 1, 2025 | May 31, 2029 | HASSANI NAJAFABADI, ALIREZA | reporter.nih.gov |
| Sulfated Non-Anticoagulant Heparin Nanoparticle (VVP728) for Sickle Cell Disease Management | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $3,058,782 | September 23, 2019 | June 30, 2026 | KORCZAK, BOZENA | reporter.nih.gov |
| Streamlined and comprehensive circulating tumor exosome profiling by microfluidic arrayed nanoplasmonic sensors and actuators | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2025 | $3,052,798 | June 15, 2021 | March 31, 2027 | SHIH, WEI-CHUAN | reporter.nih.gov |
| RNA modifications in apolipoprotein regulation by environmental exposures | NIH | National Institute of Environmental Health Sciences | 2025 | $3,051,769 | September 11, 2025 | August 31, 2029 | KLINGE, CAROLYN M. | reporter.nih.gov |
| Microengineering vascularized and innervated bone-like scaffolds as an alternative to autologous bone grafts | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $3,048,776 | August 1, 2021 | April 30, 2027 | BERTASSONI, LUIZ EDUARDO | reporter.nih.gov |
| ErythroMer: Nanoscale BioSynthetic Red Cell Substitute | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $3,043,060 | May 11, 2017 | May 31, 2027 | ALP, ESMA | reporter.nih.gov |
| The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,039,522 | December 1, 2021 | November 30, 2026 | CHEN, HONG | reporter.nih.gov |
| In Situ Albumin Binding siRNAs for Triple Negative Breast Cancer Tumor Penetration and Molecularly Targeted Therapy | NIH | National Cancer Institute | 2021 to 2025 | $3,035,458 | July 5, 2021 | June 30, 2027 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated Pneumonia | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,027,494 | July 1, 2023 | June 30, 2028 | NIZET, VICTOR | reporter.nih.gov |
| The novel role of beta3 integrin in regulating alloimmunity | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,014,928 | February 14, 2022 | January 31, 2027 | ABDI, REZA | reporter.nih.gov |
| New BDNF Nanoparticles for Early Treatment of Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2024 | $2,998,661 | September 15, 2017 | August 31, 2025 | VITALIANO, FRANCO | reporter.nih.gov |
| Improving diagnostic sensitivity for difficult-to-lyse microbial samples with nanodroplet technology | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,995,731 | August 3, 2020 | April 30, 2026 | KASOJI, SANDEEP | reporter.nih.gov |
| Molecular Mechanisms Governing Vascular Cell Function and Phenotype in Health and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,993,449 | April 1, 2021 | March 31, 2026 | CHEN, HONG | reporter.nih.gov |
| Clinic-Ready MACH-1 Gene Gun for delivery of a universal influenza DNA vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,964,030 | September 1, 2023 | August 31, 2026 | FRIZZELL, HANNAH | reporter.nih.gov |
| SynerGel: A Novel Tumor Microenvironment-Modulating Hydrogel for Local Immunotherapy | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,957,648 | July 1, 2021 | April 30, 2027 | YOUNG, SIMON | reporter.nih.gov |
| Therapeutic Targets for Niemann-Pick Type C Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,954,773 | August 15, 2021 | July 31, 2026 | LIEBERMAN, ANDREW P | reporter.nih.gov |
| Handheld and population-based sequencing for rapid detection of new and repurposed drug resistance in M. tuberculosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,952,078 | March 1, 2025 | February 28, 2027 | METCALFE, JOHN ZAPATA | reporter.nih.gov |
| Commercialization of Safe and Effective Locoregional Head and Neck Cancer Therapy | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2023 | $2,946,707 | September 1, 2014 | January 31, 2025 | GOLDBERG, MANIJEH N | reporter.nih.gov |
| Developing a Multi-epitope Pan-Coronavirus Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,944,787 | August 7, 2020 | July 31, 2025 | BENMOHAMED, LBACHIR | reporter.nih.gov |
| Develop combinatorial non-viral and viral CRISPR delivery for lung diseases | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $2,938,558 | September 10, 2018 | August 31, 2024 | GAO, GUANGPING | reporter.nih.gov |
| Combined adjuvant approaches for enhancement of SARS-CoV-2 vaccine efficacy | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,917,054 | June 1, 2022 | May 31, 2027 | WONG, PAMELA TINMOI | reporter.nih.gov |
| Engineering the Immune Response of a Self-replicating and Adjuvanting RNA HIV-1Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,913,796 | April 9, 2021 | March 31, 2024 | KHANDHAR, AMIT PRAFUL | reporter.nih.gov |
| Changing Cultures in Sepsis: Rapid single-cell pathogen identification and antibiotic susceptibility testing directly from whole blood | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,910,960 | June 15, 2020 | May 31, 2026 | YANG, SAMUEL | reporter.nih.gov |
| Uncleaved prefusion-optimized trimers on nanoparticles as HIV vaccines | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,907,216 | December 1, 2018 | August 31, 2024 | ZHU, JIANG | reporter.nih.gov |
| MAPs for Peds: Development of a Microarray Patch for Delivery of Long-Acting Antiretrovirals for Treatment of Pediatric HIV Infection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,906,725 | March 16, 2020 | March 31, 2026 | CHOY, ROBERT KWAI MING | reporter.nih.gov |
| New Engineering Strategy for Harnessing Immune System against Head and Neck Cancer | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,903,162 | July 1, 2021 | April 30, 2026 | MOON, JAMES J. | reporter.nih.gov |
| Rapid response to pandemic influenza via multi-antigen RNA-based vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,898,030 | February 10, 2022 | August 31, 2026 | CHAHAL, JASDAVE | reporter.nih.gov |
| Overcoming metastatic spread of osteosarcoma with RNA loaded nanoparticles | NIH | National Cancer Institute | 2022 to 2025 | $2,889,170 | September 1, 2022 | August 31, 2027 | SAYOUR, ELIAS | reporter.nih.gov |
| Dual drug delivery to lung/blood interface in respiratory infections. | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,888,500 | April 20, 2021 | March 31, 2025 | MUZYKANTOV, VLADIMIR R | reporter.nih.gov |
| A Testing Program to Identify Novel Agents for Treatment of Pediatric and AYA High-Risk Sarcoma, Kidney and Liver Cancer | NIH | National Cancer Institute | 2021 to 2025 | $2,862,121 | September 1, 2021 | June 30, 2026 | KURMASHEVA, RAUSHAN | reporter.nih.gov |
| High-sensitivity Immunomagnetic System for "Liquid Biopsy" of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $2,832,824 | February 1, 2021 | December 31, 2026 | MAO, HUI | reporter.nih.gov |
| Exosomes as carriers of cancer therapeutics | NIH | National Cancer Institute | 2021 to 2025 | $2,827,587 | September 14, 2021 | August 31, 2027 | RAMESH, RAJAGOPAL | reporter.nih.gov |
| Translational Research for Retinal Degeneration Therapies | NIH | National Eye Institute | 2021 to 2024 | $2,827,259 | September 30, 2007 | August 31, 2025 | BELTRAN, WILLIAM A. | reporter.nih.gov |
| NANOPHOTOSENSITIZERS FOR REGENERATIVE PHOTOTHERAPY | NIH | National Cancer Institute | 2022 to 2025 | $2,822,017 | August 4, 2021 | July 31, 2027 | ACHILEFU, SAMUEL | reporter.nih.gov |
| Uncovering inversion formation in the human genome and its impact to disease. | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,819,375 | May 1, 2020 | April 30, 2026 | FONSECA, CLAUDIA CARVALHO | reporter.nih.gov |
| Targeting apoptotic cells to enhance radiotherapy | NIH | National Cancer Institute | 2022 to 2025 | $2,817,814 | September 22, 2022 | August 31, 2027 | RAO, JIANGHONG | reporter.nih.gov |
| Excitotoxicity and Mitochondrial Dysfunction in Circulatory Arrest- Brain Injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,804,967 | March 1, 2009 | April 30, 2027 | LAWTON, JENNIFER S | reporter.nih.gov |
| A Receptor-Targeted Nanoparticle PET Tracer in Human Carotid Atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,801,867 | August 1, 2022 | May 31, 2027 | WOODARD, PAMELA K | reporter.nih.gov |
| Single-Particle Analysis of Virus Capsids, Bacteria, and Extracellular Vesicles | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,798,391 | June 1, 2021 | May 31, 2026 | JACOBSON, STEPHEN C | reporter.nih.gov |
| anti-miR-10b Nanodrug for Treatment of Breast Cancer Metastasis: Study in Companion Animals | NIH | National Cancer Institute | 2021 to 2025 | $2,789,961 | July 13, 2021 | June 30, 2027 | MOORE, ANNA | reporter.nih.gov |
| Targeted lipid nanoparticles for gene therapeutics delivery approach to eradicating HIV reservoirs | NIH | National Institute of Mental Health | 2021 to 2025 | $2,789,702 | September 23, 2019 | February 28, 2030 | GENDELMAN, HOWARD E | reporter.nih.gov |
| Circulatronics: A New Paradigm for Biomedical Implants | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,782,500 | September 1, 2022 | August 31, 2027 | SARKAR, DEBLINA | reporter.nih.gov |
| Mechanosensitive M7G epitranscriptome in endothelial health and disease | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,773,984 | December 22, 2021 | November 30, 2026 | HE, CHUAN | reporter.nih.gov |
| Lipid nanoparticle adjuvants for mRNA vaccines: composition-function relation and mechanism of action | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,771,888 | September 1, 2020 | April 30, 2030 | PARDI, NORBERT | reporter.nih.gov |
| Supramolecular biomaterials for tuning the inflammatory properties of the complement system | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,759,425 | June 1, 2022 | May 31, 2027 | COLLIER, JOEL H | reporter.nih.gov |
| Micro-nanotechnologies for the analysis of islet-derived extracellular vesicles implicated in Type 1 Diabetes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,758,753 | September 19, 2022 | June 30, 2027 | NG, ALPHONSUS | reporter.nih.gov |
| Regulation of Endometriotic Lesion Development by NOTCH1 | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,751,967 | April 1, 2021 | February 28, 2027 | FAZLEABAS, ASGERALLY T. | reporter.nih.gov |
| Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivors | NIH | National Cancer Institute | 2021 to 2025 | $2,750,972 | July 12, 2021 | June 30, 2027 | NGEN, ETHEL JOSO | reporter.nih.gov |
| Long-Acting RNAi Therapy for Atherosclerosis and Insulin Resistance | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,745,822 | July 1, 2021 | June 30, 2026 | SHI, JINJUN | reporter.nih.gov |
| Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors | NIH | National Cancer Institute | 2021 to 2025 | $2,742,888 | April 1, 2021 | March 31, 2027 | ZAMBONI, WILLIAM C | reporter.nih.gov |
| Systemic RNA Delivery to Tumors | NIH | National Cancer Institute | 2021 to 2025 | $2,731,905 | December 21, 2015 | June 30, 2027 | SHI, JINJUN | reporter.nih.gov |
| Development of microRNA (miR)-based cell-targeted polymeric nanoparticles for myeloma therapy | NIH | National Cancer Institute | 2021 to 2025 | $2,723,368 | February 9, 2021 | March 31, 2027 | CARRASCO, RUBEN D | reporter.nih.gov |
| Expanding early cancer detection with high throughput OCEANA - Ovarian Cancer Exosome Analysis with Nanoplasmonic Array | NIH | National Cancer Institute | 2023 to 2025 | $2,713,023 | September 19, 2023 | August 31, 2028 | LEE, HAKHO | reporter.nih.gov |
| Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,705,917 | March 10, 2020 | February 28, 2026 | DE VLAMINCK, IWIJN | reporter.nih.gov |
| Nano and biomolecular engineered technologies for neoantigen-specific T cell capture and characterization | NIH | National Cancer Institute | 2021 to 2025 | $2,704,913 | September 16, 2021 | June 30, 2027 | HEATH, JAMES R. | reporter.nih.gov |
| Controlling complement to unleash nanomedicine for acute critical illnesses | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,697,599 | February 1, 2022 | January 31, 2026 | BRENNER, JACOB | reporter.nih.gov |
| Covalent Chemistry on Nanosubstrates Enables Molecular Analysis of Purified Extracellular Vesicles in Hepatocellular Carcinoma | NIH | National Cancer Institute | 2021 to 2024 | $2,695,903 | July 7, 2020 | June 30, 2026 | TSENG, HSIAN-RONG | reporter.nih.gov |
| Towards rapid measurement of antibiotics in critical care setting | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,687,863 | September 1, 2022 | May 31, 2027 | STOJANOVIC, MILAN N | reporter.nih.gov |
| Amelogenin Nanoribbons In Enamel Development And Engineering | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,685,497 | April 1, 2022 | March 31, 2027 | HABELITZ, STEFAN FRIEDRICH | reporter.nih.gov |
| In vivo CRISPR engineering of B cells to produce anti-HIV broadly neutralizing antibodies using novel nanoparticles | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,680,549 | June 8, 2022 | April 1, 2025 | ADAIR, JENNIFER EILEEN | reporter.nih.gov |
| Nanoparticle-based development for HIV-1 biomolecule delivery | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,678,779 | September 15, 2021 | July 31, 2026 | HASSELL, THOMAS | reporter.nih.gov |
| Negative regulators of endothelial regeneration in aging lungs and ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,661,375 | June 1, 2022 | March 31, 2026 | ZHAO, YOU-YANG | reporter.nih.gov |
| Fusion peptide directed immunogens that elicit neutralizing and protective antibodies in non-human primates | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,658,042 | March 18, 2019 | February 28, 2025 | WARD, ANDREW BARRETT | reporter.nih.gov |
| " Investigating the Protective Efficacy of SIV/HIV T and B cell Immunity Induced by RNA Replicons.” | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,651,252 | March 1, 2023 | February 28, 2027 | GAIHA, GAURAV DAS | reporter.nih.gov |
| A targeted anti-HIV drug delivery to the GALT | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,649,778 | July 16, 2020 | June 30, 2027 | ROY, UPAL | reporter.nih.gov |
| High-throughput single-molecule protein identification via super-resolution imaging | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $2,639,000 | September 1, 2018 | July 31, 2024 | YIN, PENG | reporter.nih.gov |
| Detecting pathogen and host factors on extracellular vesicles for pediatric TB diagnosis and management | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,633,435 | March 17, 2017 | June 30, 2028 | HU, TONY Y. | reporter.nih.gov |
| Biogenic Gas Nanostructures as Molecular Imaging Reporters for Ultrasound | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2025 | $2,631,696 | January 1, 2024 | December 31, 2027 | SHAPIRO, MIKHAIL | reporter.nih.gov |
| Nanotechnology enabled quantitative imaging of dendritic cell anti-cancer vaccines | NIH | National Cancer Institute | 2025 | $2,628,974 | August 15, 2025 | July 31, 2029 | RINALDI-RAMOS, CARLOS M | reporter.nih.gov |
| Regulation of germinal center responses by SARS-CoV-2 messenger RNA vaccines | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,622,660 | February 9, 2022 | January 31, 2027 | LOCCI, MICHELA | reporter.nih.gov |
| PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitization | NIH | National Cancer Institute | 2021 to 2024 | $2,622,473 | March 1, 2021 | February 28, 2026 | BASILION, JAMES PETER | reporter.nih.gov |
| Image-guided cancer therapy using heat activatable CAR T cells | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,619,925 | September 15, 2022 | June 30, 2027 | EMELIANOV, STANISLAV Y | reporter.nih.gov |
| Overcoming the blood-brain barrier with nanoparticle vaccines against gliomas | NIH | National Cancer Institute | 2021 to 2025 | $2,618,523 | February 1, 2021 | January 31, 2026 | SAYOUR, ELIAS | reporter.nih.gov |
| Development of a Mucosal Nanoemulsion-Adjuvanted RSV Vaccine using Recombinant Pre-Fusion F Protein | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,617,783 | September 1, 2020 | December 31, 2025 | TRABBIC, KEVIN | reporter.nih.gov |
| Engineering Dual-Targeted Nanoplatforms to Effectively Treat NSCLC. | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,613,356 | September 30, 2022 | May 31, 2027 | KANNAN, RAGHURAMAN | reporter.nih.gov |
| Personalized neuroblastoma vaccines | NIH | National Cancer Institute | 2023 to 2025 | $2,604,046 | August 1, 2023 | July 31, 2028 | MARIS, JOHN M | reporter.nih.gov |
| PLK1 and EGFR targeted nanoconstruct as a monotherapy and a radiation sensitizer for lung cancer | NIH | National Cancer Institute | 2023 to 2025 | $2,602,500 | July 6, 2023 | August 31, 2027 | NGAMCHERDTRAKUL, WORAPOL | reporter.nih.gov |
| Flow Acceleration for Stroke Thrombolysis (FAST) System | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,595,730 | July 15, 2021 | December 31, 2023 | CREIGHTON, FRANCIS MILTON | reporter.nih.gov |
| Protein-based Self-assembly and Disassembly of Nanostructures | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,591,033 | April 1, 2020 | March 31, 2030 | THAYUMANAVAN, SANKARAN | reporter.nih.gov |
| Silica Nephropathy and Chronic Kidney Disease of Unknown Etiology | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,589,029 | July 7, 2020 | March 31, 2030 | BROWN, JARED MICHAEL | reporter.nih.gov |
| Novel nano-vaccine technology for inducing immunity against gliomas | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,581,798 | July 15, 2021 | June 30, 2026 | MOON, JAMES J. | reporter.nih.gov |
| Endothelial Dysfunction in the Development of Aortic Degeneration, Dissection, and Rupture | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,578,374 | July 15, 2022 | June 30, 2026 | SHEN, YING H. | reporter.nih.gov |
| Targeted genetic engineering of B cells to induce protective antibody responses to viral pathogens | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $2,577,835 | July 5, 2022 | June 30, 2027 | ADAIR, JENNIFER EILEEN | reporter.nih.gov |
| Delivering inhalable nanoparticles containing AI-optimized CFTR mRNA with a novel microfluidic device for treatment of CF | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,575,533 | April 1, 2019 | April 30, 2029 | SAHAY, GAURAV | reporter.nih.gov |
| Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancer | NIH | National Cancer Institute | 2021 to 2025 | $2,571,973 | July 1, 2021 | June 30, 2027 | YANG, LILY | reporter.nih.gov |
| A magnetic particle imager (MPI) for functional brain imaging in humans | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2022 | $2,561,408 | September 26, 2017 | February 28, 2025 | WALD, LAWRENCE L | reporter.nih.gov |
| Developing Durable, Env-Boosted CAR T Cells for HIV Cure | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,557,695 | November 2, 2022 | October 31, 2027 | PETERSON, CHRISTOPHER W | reporter.nih.gov |
| Multimodal Optical Imaging on the Effect of Maternal Polysubstance Exposure on Fetal Brain Microvessel Function | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,556,302 | January 1, 2016 | July 31, 2027 | LARIN, KIRILL V | reporter.nih.gov |
| Mechanisms underlying edible exosome-like nanoparticles for prevention of brain inflammation | NIH | National Center for Complementary & Integrative Health | 2022 to 2025 | $2,548,676 | December 1, 2015 | May 31, 2027 | ZHANG, HUANG-GE | reporter.nih.gov |
| Roles of Noncoding RNA in Bone Regeneration | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $2,547,514 | March 1, 2016 | August 31, 2025 | CHEN, JAKE JINKUN | reporter.nih.gov |
| VACCINE ADJUVANT DISCOVERY PROGRAM (VADP) | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $2,547,484 | September 30, 2025 | September 29, 2026 | LEVY, OFER | reporter.nih.gov |
| Development of a multi-modal targeted nanotherapeutic to prevent restenosis in an atherosclerotic environment | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,544,484 | July 18, 2022 | June 30, 2027 | TSIHLIS, NICK DIMITRIOS | reporter.nih.gov |
| Synthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human Transcriptomes | NIH | National Human Genome Research Institute | 2023 to 2025 | $2,539,431 | April 1, 2023 | January 31, 2027 | ROUHANIFARD, SARA HAKIM | reporter.nih.gov |
| Host Glycomic Modulation of HIV-associated Neuro-inflammation During Viral Suppression | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,534,766 | May 1, 2020 | March 31, 2025 | ABDEL MOHSEN, MOHAMED | reporter.nih.gov |
| HER2-targeting transformable nanotherapeutic platform against HER2+ cancers | NIH | National Cancer Institute | 2021 to 2024 | $2,533,940 | February 11, 2020 | January 31, 2026 | LAM, KIT S | reporter.nih.gov |
| Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines | NIH | National Cancer Institute | 2021 to 2025 | $2,533,780 | February 8, 2010 | August 31, 2026 | XU, BING | reporter.nih.gov |
| Structure and dynamics of exocytotic fusion pores | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,529,847 | December 1, 2016 | November 30, 2024 | CHAPMAN, EDWIN R | reporter.nih.gov |
| NEW CHEMICAL PROBES ENABLE MASS SPECTROMETRY-BASED FOOTPRINTING OF HUMAN PROTEIN STRUCTURE IN LIPID MEMBRANES AND CELLS | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,526,062 | March 1, 2019 | February 28, 2027 | LI, WEIKAI | reporter.nih.gov |
| Developing gene editing platforms for retinal degeneration. | NIH | National Eye Institute | 2022 to 2025 | $2,519,176 | September 30, 2022 | June 30, 2027 | SAHAY, GAURAV | reporter.nih.gov |
| Nanopore based profiling of epigenetic state | NIH | National Human Genome Research Institute | 2021 to 2024 | $2,513,355 | August 1, 2021 | May 31, 2026 | TIMP, WINSTON GEORGE | reporter.nih.gov |
| Decidual NK response to infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,507,391 | June 19, 2019 | May 31, 2024 | LIEBERMAN, JUDY | reporter.nih.gov |
| Next generation transcranial ultrasound-based neuromodulation using phase shift nanoemulsions | NIH | National Institute of Mental Health | 2023 to 2025 | $2,505,534 | February 1, 2023 | April 23, 2025 | CASKEY, CHARLES F | reporter.nih.gov |
| Engineering a novel biomaterial for oxygen transport applications | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,500,453 | January 15, 2021 | December 31, 2025 | PALMER, ANDRE FRANCIS | reporter.nih.gov |
| Enhanced Delivery of Thrombolytic Carriers for Empyema | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,499,662 | July 15, 2021 | June 30, 2026 | KOMISSAROV, ANDREY | reporter.nih.gov |
| Notch signaling in diabetic wounds | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,497,010 | May 1, 2021 | April 30, 2026 | GALLAGHER, KATHERINE ANN | reporter.nih.gov |
| Development of anti-inflammatory nanodrug for endometriosis treatment | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,492,373 | September 30, 2022 | June 30, 2027 | KIM, TAEHO | reporter.nih.gov |
| Developing macrophage reprogramming mRNA nanocarriers for initial clinical testing | NIH | National Cancer Institute | 2021 to 2024 | $2,491,070 | April 1, 2022 | July 31, 2025 | STEPHAN, MATTHIAS | reporter.nih.gov |
| TERT mRNA lipid nanoparticles to extend telomeres to treat alcoholic hepatitis | NIH | National Institute on Alcohol Abuse and Alcoholism | 2023 to 2024 | $2,484,849 | September 10, 2020 | August 31, 2025 | RAMUNAS, JOHN | reporter.nih.gov |
| Evaluation of the therapeutic potential of exclusive antagonists of extrasynaptic NMDA receptors for the treatment of opioid use disorder | NIH | National Institute on Drug Abuse | 2023 to 2025 | $2,484,468 | September 30, 2019 | April 30, 2027 | MOLOKANOVA, ELENA | reporter.nih.gov |
| The role of AEG-1 in NASH and NASH-HCC | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,484,379 | July 25, 2016 | December 31, 2025 | SARKAR, DEVANAND | reporter.nih.gov |
| Exploiting sex-dependent brain injury response for nanoparticle therapeutics | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,482,558 | January 1, 2021 | November 30, 2025 | STABENFELDT, SARAH E | reporter.nih.gov |
| An acoustofluidic device for diagnosing preclinical Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2022 | $2,481,780 | August 1, 2019 | February 28, 2025 | WANG, LIN | reporter.nih.gov |
| Organ banking for transplant--kidney cryopreservation by vitrification and novel nanowarming technology | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,474,268 | April 13, 2018 | March 31, 2027 | FINGER, ERIK BRIAN | reporter.nih.gov |
| Manipulating nucleic acids: applications in RNA biosensing, single-molecule analysis, and DNA nanotechnology | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,472,315 | August 1, 2017 | July 31, 2027 | HALVORSEN, KEN A | reporter.nih.gov |
| Cell-Selective Therapies for Coronary Artery Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,469,740 | July 15, 2015 | December 31, 2026 | TOTARY-JAIN, HANA | reporter.nih.gov |
| Toward translation of a plant virus-based in situ vaccination nanotechnology | NIH | National Cancer Institute | 2022 to 2025 | $2,469,213 | August 22, 2022 | July 31, 2026 | STEINMETZ, NICOLE FRANZISKA | reporter.nih.gov |
| Bioprinting Plant Virus Nanoparticles for Immunotherapy and Relapse Prevention of Ovarian Cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,467,441 | July 1, 2020 | June 30, 2025 | STEINMETZ, NICOLE FRANZISKA | reporter.nih.gov |
| Targeting LIGHT for treatment of glomerulonephritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,466,907 | September 1, 2025 | August 31, 2029 | KASINATH, VIVEK | reporter.nih.gov |
| New way in delivering immunomodulatory drugs in T1D | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,465,695 | February 17, 2022 | January 31, 2026 | ABDI, REZA | reporter.nih.gov |
| Long-acting multi prevention implant for 2-year contraception and HIV PrEP | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,464,240 | April 1, 2023 | March 31, 2028 | GRATTONI, ALESSANDRO | reporter.nih.gov |
| TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION | NIH | National Cancer Institute | 2021 to 2024 | $2,460,645 | August 1, 2021 | July 31, 2025 | KABANOV, ALEXANDER V | reporter.nih.gov |
| Regulation of epithelial function using targeted nanowires | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,456,578 | August 5, 2022 | May 31, 2027 | KOVAL, MICHAEL H. | reporter.nih.gov |
| Targeting jmjd3 mitigates heterotopic ossification | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,447,255 | July 1, 2021 | December 31, 2026 | GALLAGHER, KATHERINE ANN | reporter.nih.gov |
| A novel bioengineering approach to restoring permanent periodontal inflammatory bone loss | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,446,598 | July 1, 2023 | April 30, 2028 | JANG, HAE LIN | reporter.nih.gov |
| Magnetofluorescent nanoplatform for glioblastoma therapy | NIH | National Cancer Institute | 2021 to 2024 | $2,444,078 | September 11, 2020 | August 31, 2025 | YU, JOHN S | reporter.nih.gov |
| New generation of long acting nucleos(t)ides and immune stimulant for treatment of chronic hepatitis B | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,444,033 | March 10, 2022 | February 28, 2027 | OSNA, NATALIA ALEKSANDR | reporter.nih.gov |
| A “STICK” theranostic nanoplatform for image-guided drug delivery to brain malignancies | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,441,420 | December 18, 2015 | May 31, 2026 | LI, YUANPEI | reporter.nih.gov |
| Personalized Cancer Therapy Guided by Photoacoustic Chemical Imaging (PACI) of Tumor Microenvironment (TME) | NIH | National Cancer Institute | 2021 to 2025 | $2,429,748 | June 1, 2020 | May 31, 2027 | WANG, XUEDING | reporter.nih.gov |
| Executing the IND-Enabling Studies for Oral PCSK9/LDLR antagonist | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,418,072 | September 1, 2024 | June 30, 2027 | ELSHOURBAGY, NABIL A | reporter.nih.gov |
| Development of magnetic hyperthermia for the systemic treatment of endometriosis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $2,416,419 | September 17, 2021 | August 31, 2025 | TARATULA, OLEH | reporter.nih.gov |
| Expansion Microscopy | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,410,432 | July 15, 2017 | January 31, 2026 | BOYDEN, EDWARD S. | reporter.nih.gov |
| Tumor-Selective Delivery Approaches for Medulloblastoma | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,405,248 | March 15, 2020 | December 31, 2024 | HELLER, DANIEL ALAN | reporter.nih.gov |
| Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,404,322 | September 30, 2018 | July 31, 2024 | GONG, SHAOQIN - | reporter.nih.gov |
| Clinical Studies for Improving Survival Rates for Oral Cancer Patients in Low Resource Settings | NIH | National Cancer Institute | 2022 to 2024 | $2,400,702 | March 1, 2022 | March 31, 2026 | GOLDBERG, MANIJEH N | reporter.nih.gov |
| Tumor Antigen Targeted Nanoparticle Therapy for Glioblastoma (GBM) | NIH | National Cancer Institute | 2023 to 2025 | $2,400,000 | August 8, 2023 | July 31, 2026 | NAGY, JON OWEN | reporter.nih.gov |
| Next generation anti-cancer drugdelivering cement for bone metastasis patients | NIH | National Cancer Institute | 2022 to 2025 | $2,399,999 | September 1, 2022 | August 31, 2027 | JANG, HAE LIN | reporter.nih.gov |
| Poly(amine-co-ester)s for Targeted Delivery In Vivo of Gene Editing Agents to Bone Marrow and Lung | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $2,399,844 | September 7, 2018 | August 31, 2024 | SALTZMAN, W. MARK | reporter.nih.gov |
| Targeting CD180 to induce anti-KSHV response in nonhuman primates | NIH | National Cancer Institute | 2024 to 2025 | $2,397,203 | August 1, 2024 | July 31, 2029 | WONG, SCOTT W | reporter.nih.gov |
| TRIM37 is a genetic determinant of racial disparity in metastatic TNBC patients | NIH | National Cancer Institute | 2021 to 2025 | $2,392,951 | April 1, 2021 | March 31, 2027 | BHATNAGAR, SANCHITA | reporter.nih.gov |
| Exploring the role of oxytocin in the regulation of neuronal excitability | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,392,065 | May 1, 2021 | March 31, 2026 | ESCAYG, ANDREW P | reporter.nih.gov |
| Spatiotemporal interrogation of molecular mechanobiololgy at the cell-cell interface with nanotechnology tools | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,391,492 | March 1, 2020 | November 30, 2025 | JUN, YOUNG-WOOK | reporter.nih.gov |
| Drug-eluting fibers for on-demand and extended protection against HIV | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,382,973 | March 22, 2019 | February 28, 2025 | WOODROW, KIM A. | reporter.nih.gov |
| New targeted BDNF nanoparticles for treatment of METH addiction and neurotoxicity | NIH | National Institute on Drug Abuse | 2021 to 2022 | $2,378,918 | September 1, 2021 | August 31, 2025 | VITALIANO, FRANCO | reporter.nih.gov |
| Nanoparticles to Track T Cell Immunotherapy Using Magnetic Particle Imaging | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,378,468 | May 15, 2022 | July 31, 2027 | RINALDI-RAMOS, CARLOS M | reporter.nih.gov |
| Molecular imaging of novel PARP inhibitor nanomedicine delivery | NIH | National Cancer Institute | 2022 to 2025 | $2,377,967 | August 12, 2022 | July 31, 2027 | VANBROCKLIN, HENRY F. | reporter.nih.gov |
| Tumor-penetrating nano-theranostics for image-guided interventions in spontaneous feline head and neck cancer | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $2,375,504 | July 1, 2020 | April 30, 2026 | LI, YUANPEI | reporter.nih.gov |
| High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,374,172 | August 6, 2021 | July 31, 2025 | CASTRO, CESAR M | reporter.nih.gov |
| Engineered Nano-formulations for STING Activation | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,363,513 | July 6, 2022 | February 28, 2027 | MOON, JAMES J. | reporter.nih.gov |
| Advancing Fluorescence Imaging-guided Partial Nephrectomy with ClearICG | NIH | National Cancer Institute | 2021 to 2024 | $2,363,386 | September 23, 2021 | August 31, 2025 | YU, MENGXIAO | reporter.nih.gov |
| Non-Invasive Prenatal Diagnostics Based on Circulating Trophoblasts | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2023 | $2,363,252 | August 15, 2019 | July 31, 2025 | TSENG, HSIAN-RONG | reporter.nih.gov |
| In situ cancer cell specific biomineralization to overcome nanoparticle delivery barriers and sensitize pancreatic cancer to radiotherapy | NIH | National Cancer Institute | 2022 to 2025 | $2,362,124 | August 2, 2022 | July 31, 2027 | SOKOLOV, KONSTANTIN V | reporter.nih.gov |
| Genome Editing the Blood-Brain Barrier with Sonoselective Focused Ultrasound | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,361,933 | May 15, 2021 | July 31, 2025 | PRICE, RICHARD J. | reporter.nih.gov |
| The Alternative Complement Pathway and Hemocompatibility of Nanosurfaces | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,361,280 | June 1, 2016 | June 30, 2025 | SIMBERG, DMITRI | reporter.nih.gov |
| Digital Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples | NIH | National Cancer Institute | 2021 to 2024 | $2,360,532 | September 25, 2020 | August 31, 2025 | HU, TONY Y. | reporter.nih.gov |
| Development of phospholipid-based nanotherapeutics for treating abdominal aortic aneurysm | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,357,862 | July 1, 2023 | May 31, 2027 | GUO, YANHONG | reporter.nih.gov |
| Formulation, Evaluation, and Phase 0 Trial of Nanoparticle Releasing Oral Thin Film for OSCC Chemoprevention | NIH | National Cancer Institute | 2022 to 2025 | $2,354,914 | December 15, 2021 | May 31, 2027 | MALLERY, SUSAN R | reporter.nih.gov |
| The dynamic architecture of living cells: Uncovering intra-organelle events at nanoscale levels | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,354,851 | September 21, 2021 | August 31, 2026 | WONG, YVETTE | reporter.nih.gov |
| Translation of a Bismuth-Gadolinium Nanoparticle for MR-guided Radiation Therapy | NIH | National Cancer Institute | 2021 to 2024 | $2,352,523 | March 1, 2020 | February 28, 2026 | BERBECO, ROSS I. | reporter.nih.gov |
| Protein-polymer nanomedicine for Sjogren's Syndrome | NIH | National Eye Institute | 2021 to 2025 | $2,348,434 | March 1, 2017 | May 31, 2025 | HAMM-ALVAREZ, SARAH F | reporter.nih.gov |
| Focused ultrasound pre-conditioning for augmented nanoparticle penetration in infiltrative gliomas | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,344,893 | April 1, 2021 | December 31, 2025 | PRICE, RICHARD J. | reporter.nih.gov |
| Lymph Node Delivery in Transplantation | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,334,750 | June 18, 2022 | May 31, 2027 | ABDI, REZA | reporter.nih.gov |
| Multi-Tissue Craniofacial Engineering using 3D-BMP9-Notch-Synergized Graphene Citrate Composite Scaffolds | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,334,479 | April 1, 2021 | January 31, 2027 | REID, RUSSELL R. | reporter.nih.gov |
| Lipid mediated oral tolerance | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,327,530 | June 16, 2022 | May 31, 2027 | BALU-IYER, SATHY VENKAT | reporter.nih.gov |
| Ultrasound-mediated gene delivery to achieve therapeutic correction of hemophilia A | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,322,835 | April 1, 2020 | March 31, 2026 | MIAO, CAROL H | reporter.nih.gov |
| Integration of adjuvant derived nanoparticles and engineered mRNA for HIV vaccine discovery | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,322,184 | December 9, 2022 | November 30, 2027 | DONG, YIZHOU | reporter.nih.gov |
| Targeted delivery of cytopathicity enhancing agents, and co-ordination with shock and kill, to reduce HIV reservoirs | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,321,906 | July 5, 2019 | June 30, 2024 | JONES, R. BRAD | reporter.nih.gov |
| Automated High-purity Exosome isolation-based AD diagnostics system (AHEADx) | NIH | National Institute on Aging | 2023 to 2025 | $2,319,985 | September 1, 2023 | May 31, 2028 | HUANG, TONY JUN | reporter.nih.gov |
| Systemic delivery of siRNA by Nanosac for checkpoint blockade immunotherapy of head and neck squamous cell cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,315,370 | February 1, 2021 | January 31, 2026 | YEO, YOON | reporter.nih.gov |
| Derivation of pancreatic islet-like organoids from human gastric stem cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,313,256 | August 24, 2022 | May 31, 2026 | RAFII, SHAHIN | reporter.nih.gov |
| Multivalent nanocluster universal influenza vaccine given by microneedle patch | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,311,653 | February 12, 2019 | January 31, 2026 | WANG, BAOZHONG | reporter.nih.gov |
| Image-Guided Intraductal Ablative Procedure for Primary Prevention of Breast Cancer | NIH | National Cancer Institute | 2022 to 2025 | $2,311,011 | December 14, 2021 | November 30, 2026 | SEMPERE, LORENZO | reporter.nih.gov |
| Towards Translation of MU-CN29: New Therapeutic Nanoparticle for Drug-Resistant NSCLC | NIH | National Cancer Institute | 2022 to 2025 | $2,310,416 | June 17, 2022 | May 31, 2027 | KANNAN, RAGHURAMAN | reporter.nih.gov |
| Targeted immuno-nanoparticles for directing antitumor immune response against breast cancer metastasis | NIH | National Cancer Institute | 2021 to 2024 | $2,308,906 | August 1, 2020 | April 30, 2025 | KARATHANASIS, EFSTATHIOS | reporter.nih.gov |
| Clinical Development of First-in-Class Therapy for Metastatic Breast Cancer | NIH | National Cancer Institute | 2021 to 2023 | $2,308,861 | April 15, 2021 | March 31, 2024 | MEDAROVA, ZDRAVKA O | reporter.nih.gov |
| Structure of HIV-1 envelope spike in the context of membrane | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,303,320 | January 16, 2020 | December 31, 2025 | CHEN, BING | reporter.nih.gov |
| Cancer under pressure: Mechanisms of adaptation to compressive stress | NIH | National Cancer Institute | 2021 to 2025 | $2,297,421 | June 1, 2019 | May 31, 2026 | HOLT, LIAM J | reporter.nih.gov |
| Pathogenesis of Postoperative Cognitive Dysfunction | NIH | National Institute on Aging | 2021 to 2025 | $2,295,061 | September 1, 2012 | April 30, 2025 | XIE, ZHONGCONG | reporter.nih.gov |
| Fluid shear stress mechanotransduction at endothelial cell-cell junctions | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,292,108 | January 1, 2021 | December 31, 2024 | SCHWARTZ, MARTIN A | reporter.nih.gov |
| Targeted delivery of a proangiogenic and promyogenic protein for regeneration of diabetic ischemic limbs | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,288,622 | May 2, 2022 | April 30, 2027 | GUAN, JIANJUN | reporter.nih.gov |
| Coupling of vascular CaV1.2 channels in health and disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,286,262 | July 1, 2015 | April 30, 2026 | NAVEDO, MANUEL F | reporter.nih.gov |
| Protection and Immunity after Polyanhydride Nanoparticle Vaccination against Avian Influenza A Virus | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,280,238 | November 14, 2022 | October 31, 2027 | LEGGE, KEVIN L | reporter.nih.gov |
| Hyperplexed Quantum Dots for Multidimensional Cell Classification in Intact Tissue | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,276,262 | July 15, 2021 | March 31, 2026 | SMITH, ANDREW MICHAEL | reporter.nih.gov |
| Artery biomechanics and vascular damage in sickle cell disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,274,529 | May 1, 2021 | April 30, 2026 | BOTCHWEY, EDWARD A. | reporter.nih.gov |
| Building a two-way communication system: Bio-orthogonal superhydrophobic nanoparticles for controlled stimulation and real-time sensing of neurotransmitters | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,271,467 | September 15, 2022 | August 31, 2027 | MOUSAVI, MARAL | reporter.nih.gov |
| mRNA Expression Profiling from Extracellular Vesicles (EVs): Generating a Rapid Diagnostic for Stroke | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,269,242 | July 1, 2022 | March 31, 2027 | SOPER, STEVEN ALLAN | reporter.nih.gov |
| Dengue virus mRNA lipid nanoparticle vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,268,440 | August 12, 2021 | July 31, 2025 | RICHNER, JUSTIN | reporter.nih.gov |
| IRI, innate immunity and transplant rejection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,266,791 | March 15, 2021 | February 28, 2026 | ABDI, REZA | reporter.nih.gov |
| Intrapleural immunotherapeutic nanoparticles for MPE treatment | NIH | National Cancer Institute | 2021 to 2025 | $2,266,085 | August 1, 2021 | July 31, 2027 | ZHAO, DAWEN | reporter.nih.gov |
| Biostimulatory nanofiber-hydrogel composite for soft tissue remodeling | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,263,220 | February 1, 2022 | January 31, 2027 | REDDY, SASHANK K | reporter.nih.gov |
| Optimizing a Universal Influenza Subunit Nano/Microparticulate Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,261,035 | January 15, 2020 | December 31, 2025 | AINSLIE, KRISTY M | reporter.nih.gov |
| Development of a rapid, pan fungal diagnostic assay | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,260,602 | February 1, 2021 | January 31, 2027 | WICKES, BRIAN | reporter.nih.gov |
| Fibroblast Growth Factor and Energy Metabolism | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,257,939 | July 3, 2015 | March 31, 2026 | TSENG, YU-HUA | reporter.nih.gov |
| Spherical Nucleic Acid nano-architectures as first-in-class cGAS agonists for the immunotherapeutic treatment of Glioblastoma. | NIH | National Cancer Institute | 2022 to 2025 | $2,256,713 | September 23, 2022 | August 31, 2027 | STEGH, ALEXANDER H. | reporter.nih.gov |
| A stem cell activated cryogel bioscaffold that restores islet bioenergetics while providing oxygen and nutrients at extravascular sites of transplantation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,251,861 | April 1, 2022 | March 31, 2027 | THAKOR, AVNESH SINH | reporter.nih.gov |
| Mechanisms of Nanoparticle Modulation of Allergic Lung Disease | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $2,246,746 | September 1, 2021 | June 30, 2027 | BONNER, JAMES CHRISTOPHER | reporter.nih.gov |
| Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome | NIH | National Human Genome Research Institute | 2021 to 2023 | $2,244,552 | May 1, 2021 | February 29, 2024 | FANG, GANG | reporter.nih.gov |
| Novel Nano-immunotherapy for Treatment of Non-small Cell Lung Cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,243,532 | September 23, 2021 | November 30, 2025 | NGAMCHERDTRAKUL, WORAPOL | reporter.nih.gov |
| Distinct Ion Channel Pools and Intercalated Disk Nanoscale Structure Regulate Cardiac Conduction | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,241,276 | April 20, 2023 | January 31, 2028 | WEINBERG, SETH HOWARD | reporter.nih.gov |
| A nanopore biosensor for leveling Mtb antigens in blood | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,238,457 | June 15, 2022 | May 31, 2028 | LYON, CHRISTOPHER J | reporter.nih.gov |
| A pH Responsive Transistor-like Nanoprobe for Sensitive Detection of Unknown Primary Cancers of the Head and Neck | NIH | National Cancer Institute | 2022 to 2025 | $2,234,520 | June 1, 2022 | May 31, 2027 | SUMER, BARAN D | reporter.nih.gov |
| Improved Nanoparticle Targeting of Tissue Myeloid Cells for HIV-1 Long-acting Pre-exposure Prophylaxis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,233,984 | March 17, 2023 | February 28, 2027 | REINHARD, BJOERN MARKUS | reporter.nih.gov |
| Molecular Mechanisms of Organelle Formation in Bacteria | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,233,011 | May 1, 2018 | April 30, 2028 | KOMEILI, ARASH | reporter.nih.gov |
| An electrophysiology platform that enables robust, scalable and long-term intracellular recording of cardiomyocytes | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,230,525 | July 1, 2022 | June 30, 2026 | CUI, BIANXIAO | reporter.nih.gov |
| Novel Nanomedicine-Based Therapeutic Approach For Treatment of Cancer Cachexia | NIH | National Cancer Institute | 2021 to 2025 | $2,226,892 | May 1, 2024 | April 30, 2027 | TARATULA, OLEH | reporter.nih.gov |
| Blood transcriptomics as CT adjuvant to exclude hemorrhage in acute stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,222,366 | July 15, 2020 | April 30, 2026 | MELLER, ROBERT | reporter.nih.gov |
| Integrated Nano-Opto-Fluidic System on Sapphire towards Single-Molecule Protein Sequencing | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $2,222,126 | September 1, 2022 | August 31, 2027 | WANG, CHAO | reporter.nih.gov |
| Novel nanoparticles to stimulate therapeutic angiogenesis in peripheral arterial disease | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,221,837 | May 2, 2022 | April 30, 2027 | NGUYEN, KYTAI TRUONG | reporter.nih.gov |
| A Platform Technology to Genetically Reprogram Cancer Cells for Enhanced Immunotherapy | NIH | National Cancer Institute | 2021 to 2025 | $2,221,249 | July 1, 2025 | June 30, 2027 | TZENG, STEPHANY YI | reporter.nih.gov |
| Rational in situ programming of cancer vaccine-responding T-cell clones | NIH | National Cancer Institute | 2021 to 2025 | $2,219,015 | July 1, 2021 | June 30, 2026 | STEPHAN, MATTHIAS | reporter.nih.gov |
| Fluorescent Indocarbocyanine PEGylated Lipid Nanoparticles for Understanding and Overcoming Barriers to Drug Delivery in Invasive Glioblastoma | NIH | National Cancer Institute | 2022 to 2025 | $2,215,107 | August 1, 2022 | July 31, 2027 | SIMBERG, DMITRI | reporter.nih.gov |
| Role of particle surface functionalization in inflammation | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $2,213,452 | May 5, 2022 | March 31, 2027 | HOLIAN, ANDRIJ | reporter.nih.gov |
| Development of vaccine approaches to elicit broadly protective influenza-specific immune responses in infants | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,208,932 | August 5, 2020 | July 31, 2026 | ALEXANDER-MILLER, MARTHA ANN | reporter.nih.gov |
| An Antigen-Detection Blood Test for Pulmonary Tuberculosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,200,977 | July 3, 2019 | June 30, 2025 | CATANZARO, ANTONINO | reporter.nih.gov |
| Rapid and affordable magneto-nanosensors for ctDNA-guided lung cancer management | NIH | National Cancer Institute | 2021 to 2024 | $2,197,559 | August 2, 2021 | July 31, 2025 | WANG, SHAN X. | reporter.nih.gov |
| Strategies to Enhance Engineered Heart Tissue Based Myocardial Repair | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,196,794 | January 1, 2023 | November 30, 2026 | ZHU, WUQIANG | reporter.nih.gov |
| Probing Functional States and Inhibition of Flaviviral Proteases Using Nanopore Tweezers | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,190,088 | June 10, 2021 | May 31, 2027 | CHEN, MIN | reporter.nih.gov |
| Understanding and Controlling the Contribution of Fibrinolysis to Bleeding Using a Long-Acting Antifibrinolytic RNA Therapy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,182,730 | August 15, 2023 | July 31, 2027 | KASTRUP, CHRISTIAN | reporter.nih.gov |
| An RNA Nanosensor for the Diagnosis of Antibiotic Resistance in M. Tuberculosis | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,172,351 | September 1, 2025 | August 31, 2028 | FARHAT, MAHA | reporter.nih.gov |
| An immunomodulatory approach to improve oral cavity wound healing | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2024 | $2,169,288 | April 1, 2020 | March 31, 2025 | GOUDY, STEVEN L | reporter.nih.gov |
| Injectable Hydrogel Depots for Self-replicating mRNA Vaccine Delivery | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,169,016 | July 12, 2022 | June 30, 2027 | BRYERS, JAMES D. | reporter.nih.gov |
| Direct RNA sequencing using electo-optical zero mode waveguides and custom click fluorescent nucleotides | NIH | National Human Genome Research Institute | 2024 to 2025 | $2,167,349 | February 27, 2024 | January 31, 2028 | WANUNU, MENI | reporter.nih.gov |
| Eliminating the latent reservoir by targeted in vivo delivery of HIV-specific CARs | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,166,323 | March 6, 2023 | February 29, 2028 | RILEY, JAMES L. | reporter.nih.gov |
| The µSiM-hNVU - a human BBB platform for the study of brain injury mechanisms during systemic infection | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $2,162,325 | September 3, 2020 | August 31, 2025 | MCGRATH, JAMES L | reporter.nih.gov |
| Structural basis of prothrombin activation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,161,466 | December 1, 1994 | May 31, 2028 | DI CERA, ENRICO | reporter.nih.gov |
| Small extracellular vesicles as biomarkers of prognosis and response to therapy in head and neck cancer | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,157,768 | March 15, 2023 | December 31, 2027 | WHITESIDE, THERESA L. | reporter.nih.gov |
| Molecularly Engineered Lectins for Intranasal Prophylaxis and Treatment of Coronaviruses | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,156,579 | March 1, 2023 | February 29, 2028 | MARKOVITZ, DAVID MICHAEL | reporter.nih.gov |
| Acetate and Endothelial Pathobiology | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,156,080 | May 15, 2023 | April 30, 2027 | ARANY, ZOLTAN P | reporter.nih.gov |
| Heteromutivalent Peptide-Lipid Nanoconstructs as Artificial Platelet Analogues | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,150,826 | February 8, 2014 | January 31, 2026 | SEN GUPTA, ANIRBAN | reporter.nih.gov |
| Intravascular Delivery of Nanoclusters for Treatment of Deep-Seated Cancers with Magnetic Hyperthermia | NIH | National Cancer Institute | 2021 to 2024 | $2,150,799 | March 1, 2020 | February 28, 2026 | TARATULA, OLEH | reporter.nih.gov |
| Fast Multichannel Magneto-thermal Genetics | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,145,529 | September 8, 2022 | August 31, 2025 | ROBINSON, JACOB T. | reporter.nih.gov |
| Combinatorial and computational design of bnAb mRNA vaccines for HIV | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,144,122 | April 7, 2021 | March 31, 2024 | ANDERSON, DANIEL G | reporter.nih.gov |
| Systemic Delivery of Targeted Bi-Compartmental Nanoparticles for Glioblastoma Therapeutics | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,142,892 | March 15, 2022 | February 28, 2027 | LAHANN, JOERG | reporter.nih.gov |
| Mechanisms of protective memory CD8 T-cell induction by mRNA-LNP vaccines | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,140,211 | June 1, 2023 | May 31, 2028 | SIGAL, LUIS J | reporter.nih.gov |
| Integrated analysis of HCC CTCs for Liver Transplant Candidate Selection | NIH | National Cancer Institute | 2021 to 2024 | $2,139,039 | April 1, 2020 | March 31, 2026 | AGOPIAN, VATCHE | reporter.nih.gov |
| Machine Learning-Assisted Integrated Optofluidic Nanoplasmonic Biosensing for Precision Immune Profiling and Monitoring | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,138,481 | September 1, 2019 | August 31, 2029 | CHEN, PENGYU | reporter.nih.gov |
| Tissue Adhesive RNA Interference Nanoparticles to Block Progression of Posttraumatic and Spontaneous Osteoarthritis. | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,136,077 | August 22, 2022 | July 31, 2027 | DUVALL, CRAIG LEWIS | reporter.nih.gov |
| A novel cartridge-based sequencing solution for decentralized M. tuberculosis resistance detection | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,133,601 | July 7, 2023 | June 30, 2028 | METCALFE, JOHN ZAPATA | reporter.nih.gov |
| SynthoPlate: Intravenous Hemostatic Nanotechnology to Mitigate Bleeding in Thrombocytopenia | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,129,415 | March 27, 2025 | November 30, 2025 | BRUCKMAN, MICHAEL ARTHUR | reporter.nih.gov |
| Harnessing Supercoiling to Regulate DNA Activity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,128,539 | September 15, 2021 | July 31, 2027 | ZECHIEDRICH, LYNN | reporter.nih.gov |
| Theranostics of Photoreceptor-RPE-Choroid Neurovascular Unit in Eye Diseases: | NIH | National Eye Institute | 2021 to 2025 | $2,128,279 | February 1, 2017 | February 28, 2027 | ZAWADZKI, ROBERT J | reporter.nih.gov |
| Endothelial cell specification at the osteogenic and angiogenic interface in cranial bone tissue engineering | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,124,583 | September 3, 2020 | May 31, 2027 | ZHANG, XINPING | reporter.nih.gov |
| Development of multifunctional drug and immune modulator delivery nanoparticles for the treatment of cancer patients with comorbid atherosclerosis | NIH | National Cancer Institute | 2021 to 2025 | $2,122,501 | February 1, 2021 | January 31, 2026 | YANG, LILY | reporter.nih.gov |
| Macrophage-targeting Nanoplatforms as Immunotherapy against Pulmonary Infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,117,352 | July 1, 2017 | November 30, 2028 | SAILOR, MICHAEL J | reporter.nih.gov |
| Macrophage-targeted dendrimer 2-PMPA for the treatment of age-related sarcopenia | NIH | National Institute on Aging | 2022 to 2025 | $2,115,183 | August 15, 2022 | April 30, 2027 | SLUSHER, BARBARA STAUCH | reporter.nih.gov |
| Acoustofluidic Separation of Placental Nanovesicle Subpopulations in Obstetrical Diseases | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,114,799 | June 7, 2021 | June 30, 2025 | SADOVSKY, YOEL | reporter.nih.gov |
| Small and Mechanosensitive Membrane Proteins Studied with DNA-based Tools | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,114,034 | September 1, 2021 | June 30, 2027 | SCHMIDT, THORSTEN LARS | reporter.nih.gov |
| Development of a novel biodegradable inorganic nanoparticle therapeutic for cancer | NIH | National Cancer Institute | 2021 to 2024 | $2,113,155 | June 1, 2021 | May 31, 2026 | XIE, JIN | reporter.nih.gov |
| Developing platforms for studying the impact of external stresses on multispecies biofilms. | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,111,205 | September 1, 2021 | June 30, 2026 | JONES, AKHENATON-ANDREW DHAFIR | reporter.nih.gov |
| Technology Development for Biological Imaging with XFELs | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,110,247 | May 1, 2016 | May 31, 2026 | FRANK, MATTHIAS | reporter.nih.gov |
| SNSPD-DCS at 1064 nm for non-invasive monitoring of cerebral perfusion and intracranial pressure in the ICU | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $2,109,015 | September 1, 2023 | August 31, 2028 | FRANCESCHINI, MARIA ANGELA | reporter.nih.gov |
| Inorganic Chemistry Tools for Bioconjugation, Recognition and Imaging | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,102,758 | August 1, 2017 | July 31, 2027 | SPOKOYNY, ALEXANDER MICHAEL | reporter.nih.gov |
| Monocyte chemoattractant Proteins and Vascular Injury | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,102,067 | July 1, 2023 | April 30, 2027 | MISRA, SANJAY | reporter.nih.gov |
| Hair Bundle Structure and Dynamics | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2024 | $2,100,272 | June 10, 2010 | August 31, 2025 | BARR-GILLESPIE, PETER GORDON | reporter.nih.gov |
| Reprogramming Exosomes for Biomedical Applications | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2024 | $2,099,745 | September 1, 2021 | May 31, 2026 | ZHANG, YONG | reporter.nih.gov |
| Cryptococcal vaccine development based on strong immunity induced by morphological strains | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,098,848 | June 11, 2018 | April 30, 2029 | LIN, XIAORONG | reporter.nih.gov |
| Translational development of osteosarcoma (OS) extracellular vesicle (EV) matrix metalloproteinase (MMP) Activity Assay for assessing patient treatment responses | NIH | National Cancer Institute | 2025 | $2,097,875 | September 1, 2025 | August 31, 2029 | TSENG, HSIAN-RONG | reporter.nih.gov |
| Lymph node-targeted multistage chemoimmunotherapy for lymphoma | NIH | National Cancer Institute | 2021 to 2024 | $2,094,096 | April 1, 2020 | March 31, 2026 | THOMAS, SUSAN NAPIER | reporter.nih.gov |
| Extending the temporal and spatial capabilities of single-molecule methods | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $2,093,498 | September 1, 2021 | August 31, 2025 | CHU, STEVEN | reporter.nih.gov |
| Mechanisms of non-IgE Mast Cell Activation by Environmental Particulates | NIH | National Institute of Environmental Health Sciences | 2021 to 2024 | $2,087,312 | August 10, 2010 | April 30, 2026 | BROWN, JARED MICHAEL | reporter.nih.gov |
| Multimodal Imaging and Therapy of Ovarian Cancer | NIH | National Cancer Institute | 2021 to 2025 | $2,083,778 | August 20, 2021 | July 31, 2027 | KUNDRA, VIKAS | reporter.nih.gov |
| Polymeric nanoassemblies for precise tuning of immune responses | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,082,892 | July 1, 2021 | April 30, 2027 | PEARSON, RYAN MATTHEW | reporter.nih.gov |
| Nanostructured degradable bone cement for delivering novel antibiotics | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $2,078,876 | September 1, 2023 | August 31, 2027 | SENGUPTA, SHILADITYA | reporter.nih.gov |
| New tools for tick-borne pathogen surveillance | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,075,697 | December 8, 2022 | November 30, 2027 | OLIVER, JONATHAN D | reporter.nih.gov |
| Use of a Nano-Enabled Platform for Pancreatic Cancer Immunotherapy | NIH | National Cancer Institute | 2021 to 2024 | $2,074,477 | July 1, 2020 | June 30, 2025 | NEL, ANDRE ELIAS | reporter.nih.gov |
| mRNA-LNPs for ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,057,699 | June 12, 2023 | May 31, 2027 | PARHIZ, HAMIDEH | reporter.nih.gov |
| Virus-Like Nanoparticles for Non-Capsid Antigen Delivery with Virus Structure/Functional Mimicry to Activate B Cell Immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,052,840 | July 7, 2020 | June 30, 2025 | SUN, DUXIN | reporter.nih.gov |
| Transformable Theranostics for imaging-guided interventions in head and neck squamous cell carcinoma | NIH | National Cancer Institute | 2021 to 2024 | $2,050,000 | September 1, 2019 | February 28, 2026 | LIN, TZU-YIN | reporter.nih.gov |
| TOPIC TITLE: CANCER TREATMENT TECHNOLOGIES FOR LOW-RESOURCE SETTINGSPROJECT TITLE: PRV311: A STANDALONE, SAFE, EFFECTIVE, AND AFFORDABLE TREATMENT FO | NIH | National Cancer Institute | 2022 | $2,049,944 | September 15, 2022 | September 14, 2024 | GOLDBERG, MANIJEH | reporter.nih.gov |
| Process Development and Preclinical Advancement of a Novel Nanoparticle Formulation for Immune Activation | NIH | National Cancer Institute | 2023 to 2024 | $2,046,919 | September 19, 2023 | August 31, 2025 | JOHNSON, RICHARD | reporter.nih.gov |
| Development of a Universal Influenza Vaccine Against Influenza A and B Viruses | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,044,468 | November 12, 2018 | October 31, 2024 | GILL, HARVINDER SINGH | reporter.nih.gov |
| Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | NIH | National Cancer Institute | 2021 to 2025 | $2,041,762 | December 12, 2018 | November 30, 2028 | LU, ZHENG-RONG | reporter.nih.gov |
| A silicon nanopore membrane blood filter enabling anticoagulant free continuous renal replacement therapy for acute kidney injury | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $2,039,937 | September 19, 2019 | January 31, 2026 | BLAHA, CHARLES | reporter.nih.gov |
| Map Leukemia-immune Cell Talks with Nanoplasmon Ruler in CAR T-Cell Immunotherapy | NIH | National Cancer Institute | 2021 to 2024 | $2,039,396 | July 1, 2020 | June 30, 2025 | CHEN, WEIQIANG | reporter.nih.gov |
| BRAIN CONNECTS: Light microscopy for cell-type specific mesoscale to nanoscale dense connectomics | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,039,359 | August 11, 2025 | May 31, 2028 | REID, R CLAY | reporter.nih.gov |
| Innovative Research for Cancer Nanotechnology (IRCN) for Enhancing Melanoma-specific Immune Responses by the Rational Design of Spherical Nucleic Acids | NIH | National Cancer Institute | 2022 to 2025 | $2,035,485 | March 14, 2022 | February 28, 2027 | MIRKIN, CHAD A. | reporter.nih.gov |
| Nanodiamond Quantum Sensors for Free Radical Detection | NIH | National Center for Advancing Translational Sciences | 2024 to 2025 | $2,035,230 | September 10, 2021 | July 31, 2027 | TORELLI, MARCO | reporter.nih.gov |
| DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,034,826 | March 1, 2018 | February 29, 2028 | DOUGLAS, SHAWN M | reporter.nih.gov |
| In Vivo Gene Editing for HIV-1 Cure | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,034,027 | February 11, 2019 | January 31, 2025 | CHEN, IRVIN S.Y. | reporter.nih.gov |
| Sequence determinants of membraneless organelle rheology | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,031,810 | August 15, 2021 | June 30, 2026 | SCHUSTER, BENJAMIN S | reporter.nih.gov |
| Targeting specific MicroRNA to alleviate Alzheimer’s Disease pathobiology | NIH | National Institute on Aging | 2023 to 2025 | $2,031,753 | May 1, 2023 | January 31, 2028 | AMER, AMAL O | reporter.nih.gov |
| Regulation and modeling of transport across tissue barriers | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,031,571 | July 1, 2021 | May 31, 2026 | MAISEL, KATHARINA | reporter.nih.gov |
| Development of a highly sensitive and specific POCT testing asthma triggering allergic IgE | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,031,214 | February 1, 2023 | June 30, 2027 | ZHANG, KE | reporter.nih.gov |
| Fluctuations in Ionic Current through Membrane Channels | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,028,845 | December 1, 1984 | January 31, 2025 | SIGWORTH, FREDERICK J | reporter.nih.gov |
| Nanoparticle-based Intraperitoneal Delivery of Combined Chemo-radiotherapy for Treatment of Ovarian Cancer Metastases | NIH | National Cancer Institute | 2022 to 2023 | $2,025,186 | September 11, 2019 | July 31, 2025 | JAY, MICHAEL | reporter.nih.gov |
| Targeting inflammation and oxidative stress to treat acute lung injury with CNP-miR146a | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $2,024,083 | April 1, 2022 | August 31, 2025 | JACKSON, DAVID | reporter.nih.gov |
| Development of a prototype clinical theranostic platform combining Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) for the treatment of brain tumors | NIH | National Cancer Institute | 2023 to 2024 | $2,023,904 | July 1, 2023 | June 30, 2025 | GOODWILL, PATRICK | reporter.nih.gov |
| Nanoparticle-mediated reprogramming of circulating monocytes and neutrophils to decrease inflammation-mediated damage after trauma | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,023,283 | July 16, 2019 | June 30, 2025 | SHEA, LONNIE D | reporter.nih.gov |
| Integrating Real-Time Multi-System Cytokine Signaling in Chronic Disease | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,018,840 | August 1, 2021 | July 28, 2025 | WILLIAMS, RYAN MARTIN | reporter.nih.gov |
| Role of immune receptor clustering in controlling efficacy of antibody-dependent FcγRIIIa-mediated cytotoxicity by NK cells | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,017,956 | January 1, 2020 | December 31, 2025 | SYKULEV, YURI | reporter.nih.gov |
| Electrochemically generated microenvironments of oxygen and reactive oxygen/nitrogen species in extracellular medium | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,016,354 | September 15, 2020 | August 31, 2030 | LIU, CHONG | reporter.nih.gov |
| Defining the molecular interactions within nanoparticles that enable delivery of long nucleic acids | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2025 | $2,012,253 | August 1, 2018 | October 31, 2026 | SIEGWART, DANIEL JOHN | reporter.nih.gov |
| Microchip for HBV testing using HIV-infected blood samples | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,012,162 | February 6, 2023 | November 30, 2024 | SHAFIEE, HADI | reporter.nih.gov |
| Harnessing the power of exosomes for non-coding RNA delivery | NIH | National Cancer Institute | 2021 to 2023 | $2,011,604 | August 2, 2017 | July 31, 2025 | SOOD, ANIL K | reporter.nih.gov |
| Plasmonically Enhanced Point-of-care Detection of Cardiac Biomarkers by a Smart Phone | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,004,637 | February 1, 2019 | January 31, 2026 | MIKKELSEN, MAIKEN | reporter.nih.gov |
| Rapid Diagnostic Test for Respiratory Syncytial Virus by Digital Nanobubbles | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $2,002,894 | May 1, 2020 | April 30, 2026 | QIN, ZHENPENG | reporter.nih.gov |
| Ultrasound-based diagnostic and monitoring of bladder cancer treatment with drug released from nanoparticles | NIH | National Cancer Institute | 2021 to 2022 | $2,000,000 | September 7, 2018 | August 31, 2025 | ASSOULINE, JOE | reporter.nih.gov |
| In Situ Tumor Vaccination with a Nano-oligo Therapeutic to Induce Whole-body Antitumor Immune Response | NIH | National Cancer Institute | 2021 to 2022 | $2,000,000 | September 1, 2021 | February 29, 2024 | NGAMCHERDTRAKUL, WORAPOL | reporter.nih.gov |
| Interstitial Chemophototherapy with Light-Activated Nanoparticulate Doxorubicin | NIH | National Cancer Institute | 2022 to 2023 | $2,000,000 | April 6, 2020 | July 31, 2025 | SHAFIRSTEIN, GAL | reporter.nih.gov |
| Nanoscale Tools for Inosine Sequencing | NIH | National Human Genome Research Institute | 2022 to 2023 | $2,000,000 | July 1, 2022 | June 30, 2025 | ERVIN, ERIC | reporter.nih.gov |
| Development of a Therapeutic SAPNANO-ESO Vaccine for Prostate Cancer | NIH | National Cancer Institute | 2022 to 2023 | $2,000,000 | August 1, 2022 | July 31, 2026 | WANG, YICHENG | reporter.nih.gov |
| Nanovaccine for Eliciting bnAbs Against HIV-1 | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $2,000,000 | July 1, 2024 | June 30, 2027 | RAYCHAUDHURI, SANTANU | reporter.nih.gov |
| Recombinant Outer Membrane Vesicles as a Novel Adjuvant for a Malaria Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,999,755 | December 8, 2023 | November 30, 2026 | LOCHER, CHRISTOPHER | reporter.nih.gov |
| Asymmetric Single-Chain MspA nanopores for electroosmotic stretching and sequencing proteins | NIH | National Human Genome Research Institute | 2023 | $1,999,597 | June 1, 2023 | May 31, 2026 | WANUNU, MENI | reporter.nih.gov |
| Development of a chemical reaction sensor array platform for label-free, real-time kinetic analysis of enzyme-substrate reactions to enable high-throughput drug discovery | NIH | National Center for Advancing Translational Sciences | 2022 to 2023 | $1,999,400 | September 5, 2020 | July 31, 2025 | TAKULAPALLI, BHARATH | reporter.nih.gov |
| Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid Leukemia | NIH | National Cancer Institute | 2022 to 2023 | $1,999,256 | September 14, 2022 | August 31, 2025 | ADAIR, BERNADETTE MCMAHON | reporter.nih.gov |
| Developing a new drug for treating myocardial ischemia/reperfusion injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,998,610 | September 20, 2021 | August 31, 2025 | SKIDGEL, RANDAL A | reporter.nih.gov |
| Targeting integrin outside-in signaling for treating sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,993,937 | September 1, 2018 | May 31, 2025 | SKIDGEL, RANDAL A | reporter.nih.gov |
| Microvascular mechanisms of growth restriction after environmental toxicant exposure | NIH | National Institute of Environmental Health Sciences | 2023 to 2025 | $1,991,127 | January 1, 2021 | October 31, 2026 | STAPLETON, PHOEBE | reporter.nih.gov |
| Neonatal and Young Pediatric Kidney Preservation through Nanowarming and Vitrification | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,991,119 | September 14, 2018 | June 30, 2027 | WEEGMAN, BRADLEY P | reporter.nih.gov |
| Development of Next-gen Chagas DetectTM Plus Rapid test for sensitive and specific diagnosis of Chagas disease | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,988,974 | May 8, 2024 | April 30, 2027 | RAYCHAUDHURI, SYAMAL X | reporter.nih.gov |
| Novel immunotherapy against MOG antibody disease | NIH | National Center for Advancing Translational Sciences | 2024 to 2025 | $1,988,943 | July 15, 2022 | June 30, 2026 | DANIEL, WESTON | reporter.nih.gov |
| Transcriptional Regulation of Endothelial Cells after Neonatal Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,984,340 | April 1, 2018 | June 30, 2027 | KALINICHENKO, VLADIMIR | reporter.nih.gov |
| Improved Treatment of Colorectal Cancer with CF10 | NIH | National Cancer Institute | 2023 to 2024 | $1,983,010 | May 1, 2023 | April 30, 2026 | GMEINER, WILLIAM H. | reporter.nih.gov |
| Developing Long Noncoding RNA Therapy for Precision Cardiac Repair | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,982,431 | April 1, 2019 | August 31, 2027 | CHENG, KE | reporter.nih.gov |
| Pre-Clinical Development of a Intranasal Bivalent gD2/gB2 HSV-2 Mucosal Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,982,258 | March 1, 2017 | July 31, 2025 | TRABBIC, KEVIN | reporter.nih.gov |
| Nanosensor Array Platform to Capture Whole Disease Fingerprints | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $1,980,516 | June 15, 2023 | April 30, 2027 | HELLER, DANIEL ALAN | reporter.nih.gov |
| Efficacy and safety of nanoparticle mediated placental gene therapy in nonhuman primates | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,980,428 | August 7, 2023 | April 30, 2028 | JONES, HELEN N | reporter.nih.gov |
| Therapeutic Application of Painless Nerve Growth Factor to Accelerate Endochondral Fracture Repair | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2023 | $1,977,713 | September 21, 2021 | July 31, 2024 | BAHNEY, CHELSEA SHIELDS | reporter.nih.gov |
| Image-guided Bariatric Arterial Embolization (BAE) for the Treatment of Obesity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,976,122 | May 1, 2013 | January 31, 2027 | KRAITCHMAN, DARA L | reporter.nih.gov |
| Re-engineering differential regulation of ferroptosis in melanoma microenvironment | NIH | National Cancer Institute | 2023 to 2025 | $1,975,612 | July 12, 2023 | June 30, 2028 | BUNIMOVICH, YURI | reporter.nih.gov |
| MicroRNA lipid-nanoparticle based therapy targets neuroinflammation and ApoE dysregulation in Alzheimer’s disease | NIH | National Institute on Aging | 2023 to 2025 | $1,975,255 | April 15, 2023 | December 31, 2027 | WANG, WANG-XIA | reporter.nih.gov |
| Combined bioprinting with stem cell technology to regenerate skin burn wounds | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,972,718 | August 1, 2021 | May 31, 2026 | SQUARIZE, CRISTIANE | reporter.nih.gov |
| SBIR PHASE II, TOPIC 019: ELECTROSPUN BIODEGRADABLE MEMBRANE INSERTS | NIH | National Institute on Drug Abuse | 2021 | $1,972,191 | September 24, 2021 | September 23, 2023 | TATON, KRISTIN S | reporter.nih.gov |
| Nanoscale Metal-Organic Frameworks Enable Radiotherapy-Radiodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Generate Tumor Vaccines and Potentiate Immunotherapy of Head and Neck Cancers | NIH | National Cancer Institute | 2021 to 2024 | $1,972,047 | July 1, 2020 | June 30, 2025 | LIN, WENBIN | reporter.nih.gov |
| Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | NIH | National Cancer Institute | 2023 to 2025 | $1,971,026 | December 1, 2022 | November 30, 2027 | BRADY-KALNAY, SUSANN M | reporter.nih.gov |
| Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | NIH | National Cancer Institute | 2021 to 2025 | $1,969,673 | March 4, 2021 | February 28, 2027 | WANG, ZHIHUI | reporter.nih.gov |
| Dissect the molecular mechanism of a viral genome packaging motor by an integrated structural approach | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,969,630 | April 1, 2021 | March 31, 2025 | CHENG, XIAOLIN | reporter.nih.gov |
| Copper-depleting nanotheranostics for treating triple negative breast cancer | NIH | National Cancer Institute | 2021 to 2023 | $1,968,063 | September 1, 2019 | August 31, 2025 | RAO, JIANGHONG | reporter.nih.gov |
| Precision Engineering of STING-DC Immunity to Overcome Tumor Immune Evasion | NIH | National Cancer Institute | 2024 to 2025 | $1,968,000 | September 1, 2024 | August 31, 2031 | GAO, JINMING | reporter.nih.gov |
| ADDITIVE MANUFACTURING OF PDMS MICROFLUIDICS | NIH | National Center for Advancing Translational Sciences | 2023 to 2024 | $1,966,874 | April 19, 2023 | March 31, 2026 | SCHULTZ, JEFFREY | reporter.nih.gov |
| Engineering the Immune Response of a Self-replicating and Adjuvanting RNA HIV-1Vaccine | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,963,600 | April 9, 2021 | April 30, 2027 | KHANDHAR, AMIT PRAFUL | reporter.nih.gov |
| Development of three KSHV vaccine platforms and chimeric MHV68-K-G for in vivo mouse infection study | NIH | National Cancer Institute | 2024 to 2025 | $1,962,036 | September 19, 2024 | August 31, 2029 | JUNG, JAE U | reporter.nih.gov |
| Multiplexed Assay for Point-of-Care UTI Diagnosis (ID/AMR) | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,961,669 | March 1, 2024 | February 28, 2027 | BURKLUND, ALISON | reporter.nih.gov |
| SERS diagnostics platform for liquid bioapsy analysis of tumor-associated exosomes | NIH | National Cancer Institute | 2021 to 2024 | $1,960,132 | April 15, 2020 | March 31, 2025 | CARNEY, RANDY | reporter.nih.gov |
| The development of novel radiation-sensitizer based on ultra-small carbon dots | NIH | National Cancer Institute | 2021 to 2024 | $1,960,035 | July 15, 2020 | June 30, 2026 | LI, ZIBO | reporter.nih.gov |
| Nanomedicine-Based Targeting of Inflammatory Macrophages in Diabetic Wound Repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,959,971 | June 1, 2022 | May 31, 2027 | SMITH, ANDREW MICHAEL | reporter.nih.gov |
| Targeted therapy to reverse aortic aneurysms | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,959,963 | April 1, 2017 | March 31, 2027 | VYAVAHARE, NAREN R | reporter.nih.gov |
| High-throughput size-selection system for long-read sequencing library preparation | NIH | National Human Genome Research Institute | 2024 to 2025 | $1,959,900 | August 3, 2022 | June 30, 2026 | BOLES, TRUETT C | reporter.nih.gov |
| Orchestrating Tendon Regeneration through Nanoparticle Drug Delivery | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $1,958,125 | September 15, 2025 | August 31, 2028 | BENOIT, DANIELLE S. | reporter.nih.gov |
| RNA modifications by paternal exposure to arsenic and intergenerational effects on sperm quality | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $1,957,983 | April 29, 2022 | January 31, 2027 | HO, SHUK-MEI | reporter.nih.gov |
| Sialic Acid Modulation of HIV-associated Chronic Inflammaging | NIH | National Institute on Aging | 2021 to 2023 | $1,956,508 | May 1, 2019 | August 31, 2024 | ABDEL MOHSEN, MOHAMED | reporter.nih.gov |
| Immunoengineering Strategies for Musculoskeletal Trauma | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2024 | $1,955,214 | May 1, 2020 | April 30, 2026 | GULDBERG, ROBERT E | reporter.nih.gov |
| Development of plasmon-enhanced biosensing for multiplexed profiling of extracellular vesicles | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,954,920 | September 1, 2020 | August 31, 2025 | IM, HYUNGSOON | reporter.nih.gov |
| Nanopore-based sequencing of placenta-cell-type-specific extracellular RNA for real time assessment of human placenta development and function | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,954,350 | July 15, 2019 | April 30, 2025 | WILLIAMS, ZEV | reporter.nih.gov |
| Tuning multivalency for optimized ligand presentation | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $1,952,981 | September 1, 2020 | August 31, 2025 | GORMLEY, ADAM JOSEPH | reporter.nih.gov |
| Toward Translation of an Immunotherapeutic Nanomedicine for Neuroblastoma | NIH | National Cancer Institute | 2022 to 2025 | $1,952,176 | July 1, 2022 | June 30, 2027 | WILSON, JOHN TANNER | reporter.nih.gov |
| Overcoming Resistance Mechanisms in Hedgehog and Myc-amplified Medulloblastoma | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,949,505 | December 1, 2020 | November 30, 2025 | MAHATO, RAM I. | reporter.nih.gov |
| Conformal islet encapsulation for transplantation at vascularized sites to allow physiological insulin secretion | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,946,597 | July 5, 2016 | February 28, 2029 | TOMEI, ALICE | reporter.nih.gov |
| Understanding and controlling the cellular fate of fluorine-modified biologics | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,943,785 | July 1, 2021 | June 30, 2027 | MEDINA, SCOTT HAMMOND | reporter.nih.gov |
| Novel Influenza nano vaccines for broad cross protection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,941,278 | May 15, 2012 | June 30, 2025 | WANG, BAOZHONG | reporter.nih.gov |
| Combinatorial Approaches to Improved Blood-contacting Polymer Biomaterials | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,938,688 | August 15, 2020 | July 31, 2025 | SIEDLECKI, CHRISTOPHER A | reporter.nih.gov |
| Development of a DCLK1 siRNA Nanoparticle as Targeted Therapy to Treat Pancreatic Cancer | NIH | National Cancer Institute | 2021 to 2022 | $1,935,472 | August 22, 2018 | July 31, 2024 | DE OLIVEIRA, ELISEU O. | reporter.nih.gov |
| Metallo-fluorocarbon nanoemulsion for PET detection of cancer inflammation | NIH | National Cancer Institute | 2023 to 2025 | $1,934,313 | June 1, 2023 | May 31, 2027 | AHRENS, ERIC T. | reporter.nih.gov |
| Next Gen Targeted nanoparticles for Inhibiting Gli2 in Bone Metastatic Tumors | NIH | National Cancer Institute | 2023 to 2025 | $1,932,125 | June 1, 2023 | May 31, 2027 | RHOADES (STERLING), JULIE A | reporter.nih.gov |
| BIOLOGICAL FATE AND BIOCOMPATIBILITY OF SILICA-BASED NANOCONSTRUCTS | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $1,928,620 | September 28, 2007 | November 30, 2026 | GHANDEHARI, HAMID | reporter.nih.gov |
| Dendrimer-conjugated nSMase2 inhibitor as a novel therapeutic approach for Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $1,927,833 | May 1, 2020 | April 30, 2025 | RAIS, RANA | reporter.nih.gov |
| Development of a Bio-tissue Oxygenation Nanophosphor Enabled Sensing (BONES) system for Quantifying Hypoxia in Bone Marrow | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,915,320 | June 1, 2021 | February 28, 2025 | YUN, WENBING | reporter.nih.gov |
| Development of Nanoneedle Array for Painless and Long-Term Sustained Intraocular Drug Delivery | NIH | National Eye Institute | 2021 to 2025 | $1,914,931 | September 30, 2021 | July 31, 2027 | LEE, CHI HWAN | reporter.nih.gov |
| Small Scale Robotics for Automated Dental Biofilm Theranostics | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $1,913,692 | September 22, 2023 | August 31, 2026 | STEAGER, EDWARD | reporter.nih.gov |
| Engineered Polymer Nanoemulsions for Treatment of Wound Biofilm Infections | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $1,913,593 | July 24, 2018 | June 30, 2027 | ROTELLO, VINCENT M. | reporter.nih.gov |
| Nanohybrid Composites Minimize Antibiotic Resistant Infections | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,906,830 | August 20, 2024 | July 31, 2029 | LI, BINGYUN | reporter.nih.gov |
| Preclinical imaging of immune responses to chronic stress | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,905,800 | July 1, 2023 | June 30, 2028 | VAN LEENT, MANDY MARIA THERESIA | reporter.nih.gov |
| Engineered Vaccines for Neoantigen Targeted Cancer Immunotherapy | NIH | National Cancer Institute | 2022 to 2025 | $1,904,776 | July 1, 2022 | June 30, 2028 | WILSON, JOHN TANNER | reporter.nih.gov |
| Novel biomaterials for IBD treatment | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,903,299 | May 1, 2020 | April 30, 2024 | MOON, JAMES J. | reporter.nih.gov |
| A Nanocarrier Platform for Targeting Schlemm's Canal Cells | NIH | National Eye Institute | 2022 to 2025 | $1,902,955 | September 30, 2022 | July 31, 2026 | JOHNSON, MARK | reporter.nih.gov |
| Lipid nanomedicine targeting multiple signaling pathways of medulloblastoma | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,901,424 | July 15, 2022 | May 31, 2027 | MAHATO, RAM I. | reporter.nih.gov |
| Chip-Scale Intraoperative Optical Navigation with Immunotargeted Upconverting Nanoparticles | NIH | National Cancer Institute | 2023 to 2025 | $1,900,633 | June 15, 2023 | May 31, 2027 | ANWAR, MEKHAIL | reporter.nih.gov |
| Advanced testing of a hexavalent adjuvanted influenza vaccine platform for dose sparing, multiplexing, and rapid deployment | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,899,426 | June 1, 2024 | May 31, 2027 | KUTSCHER, HILLIARD | reporter.nih.gov |
| Enhancement of tumor radiation response by ultrasound-driven nanobubble stimulation | NIH | National Cancer Institute | 2021 to 2024 | $1,889,708 | August 11, 2021 | July 31, 2026 | EXNER, AGATA A | reporter.nih.gov |
| High-Throughput Electrokinetic Fractionation and Analysis of Extracellular RNA Nano-Carriers | NIH | National Cancer Institute | 2021 to 2022 | $1,887,990 | August 1, 2019 | July 31, 2023 | CHANG, HSUEH-CHIA | reporter.nih.gov |
| Nanotherapeutic enhancement of interstitial thermal therapy for glioblastoma | NIH | National Cancer Institute | 2023 to 2025 | $1,886,274 | December 1, 2022 | November 30, 2027 | WOODWORTH, GRAEME F | reporter.nih.gov |
| Eye drop formulations for enhanced penetration of water soluble antibiotics to treat infections | NIH | National Eye Institute | 2022 to 2025 | $1,885,653 | September 30, 2022 | June 30, 2027 | ENSIGN, LAURA | reporter.nih.gov |
| A Wholly Protein-based Self-assembly Nanoplatform for TNBC-specific Combination Therapy | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $1,885,144 | August 1, 2022 | April 30, 2027 | LIU, RIHE | reporter.nih.gov |
| Iron Based Coupling Media (IBCM) for MRI-guided Transcranial Ultrasound Surgeries | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $1,884,663 | September 30, 2022 | June 30, 2027 | ALLEN, STEVEN P | reporter.nih.gov |
| A nanofiber-hydrogel composite plug for perianal fistula repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,883,553 | March 1, 2023 | February 28, 2027 | MAO, HAI-QUAN | reporter.nih.gov |
| Integrative, multi-parametric characterization of the EV surface protein and nucleic acid landscape by nano-flow and sorting cytometry | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $1,880,888 | September 16, 2019 | June 30, 2025 | GHIRAN, IONITA CALIN | reporter.nih.gov |
| Dual-pronged nano-drug delivery using plant virus-like particles | NIH | National Cancer Institute | 2021 to 2025 | $1,880,163 | September 15, 2022 | August 31, 2027 | STEINMETZ, NICOLE FRANZISKA | reporter.nih.gov |
| MR Imaging of Bioscaffold-Induced Neural Progenitor Migration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,877,043 | July 1, 2021 | June 30, 2027 | MODO, MICHEL M. | reporter.nih.gov |
| RIG-I Activating Nanoparticles for Immunopotentiation | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $1,875,422 | September 30, 2022 | June 30, 2027 | WILSON, JOHN TANNER | reporter.nih.gov |
| SUPPLEMENTAL WORK-SARS-COV-2 | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $1,872,652 | April 1, 2019 | July 31, 2022 | KAYTOR, MICHAEL | reporter.nih.gov |
| Super-Resolution Microscopy of Neuronal Synapses with Advanced Imaging Tools | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,872,517 | July 1, 2017 | August 31, 2026 | SELVIN, PAUL R | reporter.nih.gov |
| Super-Resolution Fluorescence Microscopy of Synaptic Plasticity on Unmodified Brain Slices in Health and Tauopathy | NIH | National Institute on Aging | 2023 | $1,870,822 | September 1, 2023 | August 31, 2026 | SELVIN, PAUL R | reporter.nih.gov |
| Automated Cell Culture System | NIH | Office of the Director, National Institutes of Health | 2025 | $1,869,146 | May 15, 2025 | May 14, 2026 | DAMOISEAUX, ROBERT | reporter.nih.gov |
| Bio-Responsive and Immune Protein-Based Therapies for Inhibition of Proteolytic Enzymes in Dental Tissues | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $1,867,660 | March 17, 2023 | February 28, 2028 | PIOVEZAN FUGOLIN, ANA PAULA | reporter.nih.gov |
| Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIV | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,866,100 | December 1, 2023 | October 31, 2028 | ZWICK, MICHAEL B | reporter.nih.gov |
| Micro-invasive biochemical sampling of brain interstitial fluid for investigating neural pathology | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 to 2023 | $1,865,177 | February 1, 2020 | November 30, 2024 | LANGER, ROBERT SAMUEL | reporter.nih.gov |
| Feasibility for Development of a Liposome/LNP Displaying an HIV Env Trimer Protein and Containing/Incorporating an mRNA | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $1,863,405 | August 31, 2024 | August 27, 2028 | FOUTS, TIMOTHY R | reporter.nih.gov |
| Brain-Wide Genome Editing Enabled by Intravenously Administered Non-Viral Nanovectors As a Potential Therapy for Alzheimer’s Disease | NIH | National Institute on Aging | 2023 | $1,860,250 | May 15, 2023 | April 30, 2026 | GONG, SHAOQIN - | reporter.nih.gov |
| Mechanisms of epithelial alterations in diabetic cornea | NIH | National Eye Institute | 2022 to 2025 | $1,857,956 | August 1, 2001 | June 30, 2027 | LJUBIMOV, ALEXANDER V | reporter.nih.gov |
| Single molecule DNA/RNA sequencing technology based on a parallel Raman scattering readout in a coupled nanochannel/nanopore system | NIH | National Human Genome Research Institute | 2022 to 2023 | $1,852,664 | March 17, 2021 | July 31, 2024 | BRUECK, STEVEN | reporter.nih.gov |
| Nonaddictive opioid prodrug nanomedicine for musculoskeletal pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,851,532 | September 7, 2022 | July 31, 2027 | WANG, DONG | reporter.nih.gov |
| Speckle x-ray imaging: detecting early changes in lung microstructure | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,847,778 | February 1, 2023 | November 30, 2026 | NOEL, PETER B | reporter.nih.gov |
| Targeting Inflammasome with stable endocannabinoid ligand AMG315. CRISPR/Cas9 and nanotechnology study in the context of HIV and cannabinoid | NIH | National Institute on Drug Abuse | 2021 to 2024 | $1,847,120 | July 1, 2020 | May 31, 2026 | LAKSHMANA, MADEPALLI KRISHNAPPA | reporter.nih.gov |
| Synergistic Enhancement of Peripheral Nerve Defect Repair using Peptide Functionalized Aligned Nanofiber Conduits | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,840,426 | June 1, 2022 | May 31, 2027 | BECKER, MATTHEW L | reporter.nih.gov |
| Development of Universal Influenza Virus Vaccines Using Nucleoside-Modified Messenger RNA | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,837,793 | June 21, 2019 | May 31, 2024 | PARDI, NORBERT | reporter.nih.gov |
| High-throughput Clinical Hyperpolarized 13C MRI | NIH | Office of the Director, National Institutes of Health | 2025 | $1,835,840 | August 1, 2025 | July 1, 2027 | TSAI, LEO LEE | reporter.nih.gov |
| Targeting Inflammasomes in Substance Abuse and HIV | NIH | National Institute on Drug Abuse | 2021 to 2024 | $1,835,835 | July 15, 2020 | May 31, 2026 | TOBOREK, MICHAL | reporter.nih.gov |
| Long-read single-molecule protein sequencing on an array of unfoldase-coupled nanopores | NIH | National Human Genome Research Institute | 2022 to 2024 | $1,835,610 | September 21, 2022 | June 30, 2025 | NIVALA, JEFFREY MATTHEW | reporter.nih.gov |
| Nanomedicine-based approach for characterizing the epigenome in prevention of inflammation-induced preterm birth. | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,835,296 | December 21, 2022 | November 30, 2027 | ENSIGN, LAURA | reporter.nih.gov |
| Novel Carbon Nanozyme Mechanisms for Traumatic Brain Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,833,893 | September 1, 2015 | March 31, 2026 | KENT, THOMAS | reporter.nih.gov |
| Redefining Nanomedicine Beyond One-Size-Fits-All: Uncovering Mechanisms of Sex Differences and Female Life Stages in Drug Delivery | NIH | National Institute of General Medical Sciences | 2025 | $1,833,094 | September 1, 2025 | August 31, 2029 | LANIER, OLIVIA LAUREN | reporter.nih.gov |
| Nano-Engineered Lab-on-a-Chip for Assessing HuR-Regulated Exosomes for Cancer Monitoring and Targeted Therapy | NIH | National Cancer Institute | 2021 to 2023 | $1,832,571 | May 16, 2019 | April 30, 2026 | XU, LIANG | reporter.nih.gov |
| Homogenized, engineered extracellular vesicles for intracranial targeting | NIH | National Institute of Biomedical Imaging and Bioengineering | 2023 to 2025 | $1,828,339 | April 4, 2023 | March 31, 2027 | CARNEY, RANDY | reporter.nih.gov |
| CD4 T cell-targeted nanoparticle in vivo delivery of CRISPR/Cas9 genome editors for HIV cure | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,825,902 | April 8, 2019 | July 31, 2023 | HU, WENHUI | reporter.nih.gov |
| TGX-1214 - Combination Strategy for the Treatment of Advanced Pancreatic Cancer | NIH | National Cancer Institute | 2023 to 2025 | $1,822,280 | February 1, 2023 | January 31, 2028 | MACKENZIE, GERARDO GUILLERMO | reporter.nih.gov |
| IgE Suppressing Berberine Nanomedicine for Treatment of Food Allergies | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $1,814,418 | May 11, 2023 | April 30, 2026 | YANG, NAN | reporter.nih.gov |
| CMYA5 regulation of cardiac dyad structure and function | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,813,614 | December 15, 2022 | November 30, 2026 | PU, WILLIAM TSWENCHING | reporter.nih.gov |
| SMART NANPs: new molecular platform for communication with human immune system and modulation of therapeutic responses | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,813,025 | February 1, 2021 | January 31, 2027 | AFONIN, KIRILL A | reporter.nih.gov |
| Nanotechnology-based personalized treatment of metastatic ovarian cancer | NIH | National Cancer Institute | 2023 to 2025 | $1,811,714 | June 3, 2022 | May 31, 2027 | MINKO, TAMARA | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| University of Pennsylvania | Philadelphia, PA | 69 | $81.1 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 69 | $76.5 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 53 | $67.9 million | 0 | $0 |
| Stanford University | Stanford, CA | 47 | $62.1 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 35 | $46.5 million | 0 | $0 |
| Emory University | Atlanta, GA | 27 | $45.5 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 29 | $44.1 million | 0 | $0 |
| Yale University | New Haven, CT | 41 | $41.7 million | 0 | $0 |
| University of Washington | Seattle, WA | 31 | $39.1 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 17 | $39 million | 0 | $0 |
| University of Nebraska Medical Center | Omaha, NE | 27 | $36.8 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 27 | $35.1 million | 0 | $0 |
| Wistar Institute | Philadelphia, PA | 5 | $34.7 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 33 | $34.2 million | 0 | $0 |
| University of California at Davis | Davis, CA | 26 | $33.9 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 10 | $33.7 million | 0 | $0 |
| Massachusetts Institute of Technology | Cambridge, MA | 25 | $32.3 million | 0 | $0 |
| Ohio State University | Columbus, OH | 30 | $32.1 million | 0 | $0 |
| Duke University | Durham, NC | 30 | $31 million | 0 | $0 |
| Washington University | Saint Louis, MO | 26 | $29.4 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 38 | $29.3 million | 0 | $0 |
| University of Florida | Gainesville, FL | 32 | $28.6 million | 0 | $0 |
| Luminostics, Inc. | San Jose, CA | 1 | $28.6 million | 0 | $0 |
| University of Illinois at Urbana-Champaign | Urbana, IL | 25 | $28 million | 0 | $0 |
| Scripps Research Institute, the | La Jolla, CA | 15 | $27.6 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 22 | $27.5 million | 0 | $0 |
| University of Chicago | Chicago, IL | 22 | $26.1 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 28 | $25.9 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 17 | $24.4 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 12 | $23.7 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 19 | $22.4 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 23 | $22 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 7 | $21.7 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 4 | $20.5 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 22 | $20.2 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 20 | $19.9 million | 0 | $0 |
| SUNY at Buffalo | Amherst, NY | 15 | $19.8 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 20 | $19.7 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 17 | $19.5 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 23 | $19.3 million | 0 | $0 |
| University of Maryland, College Park | College Park, MD | 13 | $18.6 million | 0 | $0 |
| Michigan State University | East Lansing, MI | 13 | $18.3 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 5 | $17.9 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 25 | $17.8 million | 0 | $0 |
| Northeastern University | Boston, MA | 11 | $17.7 million | 0 | $0 |
| University of Delaware | Newark, DE | 5 | $17.4 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 16 | $17.3 million | 0 | $0 |
| University of Kansas Medical Center | Kansas City, KS | 3 | $17 million | 0 | $0 |
| Georgia Tech Research Corporation | Atlanta, GA | 20 | $17 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 20 | $16.2 million | 0 | $0 |
| University of Massachusetts Amherst | Amherst, MA | 15 | $16 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 14 | $16 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 15 | $16 million | 0 | $0 |
| Oregon State University | Corvallis, OR | 10 | $15.8 million | 0 | $0 |
| Methodist Hospital Research Institute | Houston, TX | 12 | $15.4 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 15 | $15.2 million | 0 | $0 |
| Fred Hutchinson Cancer Center | Seattle, WA | 7 | $15 million | 0 | $0 |
| Purdue University | West Lafayette, IN | 13 | $14.6 million | 0 | $0 |
| University of TX MD Anderson Can CTR | Houston, TX | 17 | $14.4 million | 0 | $0 |
| New York University | New York, NY | 9 | $14.4 million | 0 | $0 |
| University of Rochester | Rochester, NY | 15 | $14.2 million | 0 | $0 |
| Clemson University | Clemson, SC | 16 | $13.9 million | 0 | $0 |
| Virginia Commonwealth University | Richmond, VA | 15 | $13.5 million | 0 | $0 |
| Trustees of Boston University | Boston, MA | 18 | $13.5 million | 0 | $0 |
| California Institute of Technology | Pasadena, CA | 5 | $13.3 million | 0 | $0 |
| Rutgers University New Brunswick | New Brunswick, NJ | 14 | $13.2 million | 0 | $0 |
| North Carolina State University | Raleigh, NC | 13 | $13 million | 0 | $0 |
| Columbia University | New York, NY | 15 | $12.8 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 7 | $12.7 million | 0 | $0 |
| Arizona State University | Scottsdale, AZ | 15 | $12.7 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 13 | $12.7 million | 0 | $0 |
| Northwestern University | Chicago, IL | 15 | $12.7 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 10 | $12.4 million | 0 | $0 |
| Iowa State University | Ames, IA | 10 | $11.8 million | 0 | $0 |
| University of Iowa | Iowa City, IA | 13 | $11.4 million | 0 | $0 |
| Privo Technologies, LLC | Peabody, MA | 4 | $10.7 million | 0 | $0 |
| International Aids Vaccine Initiative | New York, NY | 2 | $10.7 million | 0 | $0 |
| University of South Florida | Tampa, FL | 9 | $10.6 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 11 | $10.5 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 7 | $10.5 million | 0 | $0 |
| William Marsh Rice University | Houston, TX | 10 | $10.2 million | 0 | $0 |
| University of Missouri-Columbia | Columbia, MO | 11 | $10.1 million | 0 | $0 |
| Electronic Biosciences, Inc. | San Diego, CA | 22 | $9.8 million | 0 | $0 |
| Tulane University of Louisiana | New Orleans, LA | 6 | $9.8 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 8 | $9.8 million | 0 | $0 |
| University of Oklahoma HLTH Sciences CTR | Oklahoma City, OK | 8 | $9.4 million | 0 | $0 |
| Sloan-Kettering Inst Can Research | New York, NY | 8 | $9.3 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 8 | $9.2 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 10 | $9 million | 0 | $0 |
| Dana-Farber Cancer Inst | Boston, MA | 7 | $9 million | 0 | $0 |
| Tufts University Boston | Boston, MA | 5 | $8.9 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 7 | $8.8 million | 0 | $0 |
| Cornell University | Ithaca, NY | 9 | $8.7 million | 0 | $0 |
| University of Houston | Houston, TX | 6 | $8.7 million | 0 | $0 |
| University of Connecticut | Storrs, CT | 9 | $8.6 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 9 | $8.6 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 9 | $8.4 million | 0 | $0 |
| University of Texas at Dallas | Richardson, TX | 8 | $7.9 million | 0 | $0 |
| University of Georgia Research Foundation Inc | Athens, GA | 9 | $7.9 million | 0 | $0 |
| West Virginia University Research Corporation | Morgantown, WV | 9 | $7.7 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 1,127 | $623,367,281 | 0 | $0 |
| 2024 | 1,189 | $589,133,691 | 0 | $0 |
| 2023 | 1,188 | $584,492,708 | 0 | $0 |
| 2022 | 1,152 | $539,845,033 | 0 | $0 |
| 2021 | 1,121 | $544,928,869 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
| Open opportunity | Number | Agency | Listing | Closes | Award ceiling | Why it matches |
|---|---|---|---|---|---|---|
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) | PA-24-254 | NIH | July 12, 2027 | Not listed | Notice number printed on 18 awards here | |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) | PA-24-182 | NIH | May 8, 2027 | Not listed | Notice number printed on 4 awards here | |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) | PA-24-194 | NIH | May 7, 2027 | Not listed | Notice number printed on 3 awards here | |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) | PA-25-080 | NIH | September 7, 2027 | Not listed | Notice number printed on 1 award here | |
| Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required) | RFA-AI-27-002 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required) | RFA-AI-27-005 | NIH | 93.855 | November 10, 2026 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) | PAR-25-370 | NIH | 93.855 | November 16, 2026 | $50,000 | Same assistance listing 93.855 as 384 awards here |
| Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) | PAR-25-369 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) | PAR-25-371 | NIH | 93.855 | November 18, 2026 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) | PAR-25-379 | NIH | 93.855 | January 7, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| HIV/AIDS Clinical Trials Network Leadership and Operations Centers | RFA-AI-28-001 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| HIV/AIDS Clinical Trials Network Laboratory Centers | RFA-AI-28-002 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| HIV/AIDS Clinical Trials Network Statistical and Data Management Centers | RFA-AI-28-003 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| HIV/AIDS Clinical Trials Network Clinical Trials Units | RFA-AI-28-004 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases | RFA-AI-28-014 | NIH | 93.855 | January 22, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Immune Tolerance Network (UM1 Clinical Trial Required) | RFA-AI-28-005 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed) | RFA-AI-28-012 | NIH | 93.855 | January 29, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed) | RFA-AI-28-024 | NIH | 93.855 | February 11, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
| NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed) | RFA-LM-28-001 | NIH | 93.855 | February 11, 2027 | $775,000 | Same assistance listing 93.855 as 384 awards here |
| NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) | PA-27-100 | NIH | 93.855 | April 5, 2027 | Not listed | Same assistance listing 93.855 as 384 awards here |
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.