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Data / Research funding / Microbiome

Microbiome: 3,431 NIH awards ($7.1B) to 407 organizations

3,431 NIH awards ($7.1B) in the NIH spending category Microbiome, to 407 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 3,431 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
NIEHS - Lung Microbiome Promotes Emphysema by Activating Lung Innate ImmunityNIHNational Cancer Institute2021 to 2025$2,960,824,321August 31, 2025August 30, 2026BRISCOE, LYNNreporter.nih.gov
The Long Life Family StudyNIHNational Institute on Aging2021 to 2025$60,108,132August 15, 2019June 30, 2030PROVINCE, MICHAEL A.reporter.nih.gov
Childhood Asthma in Urban Settings Clinical Research Network - Leadership CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$34,858,092April 12, 2021March 31, 2028JACKSON, DANIEL Jreporter.nih.gov
IPP: AUTOIMMUNE DISEASES STATISTICAL AND CLINICAL COORDINATING CENTER (ADSCCC)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$32,128,916February 1, 2025January 31, 2026MILLIN, CHRISTINAreporter.nih.gov
Case Comprehensive Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$28,812,474August 1, 1997March 31, 2030SCHWARTZ, GARY Kreporter.nih.gov
ATOPIC DERMATITIS RESEARCH NETWORK LEADERSHIP CENTERNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$27,224,161April 9, 2020March 31, 2027LEUNG, DONALD YMreporter.nih.gov
Environmental triggers of early-onset colorectal cancer: interactions between microplastics and pks+ E coli in early-life gut colonizationNIHNational Cancer Institute2021 to 2025$22,669,275August 1, 1997July 31, 2026TUVESON, DAVID Areporter.nih.gov
Partnerships for Biomedical Research in ArkansasNIHNational Institute of General Medical Sciences2021 to 2025$21,309,096September 30, 2001April 30, 2026CORNETT, LAWRENCE Ereporter.nih.gov
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$21,023,937April 1, 2019September 30, 2026SHARMA, ANJALIreporter.nih.gov
Alzheimer's Gut Microbiome ProjectNIHNational Institute on Aging2021 to 2023$20,743,566September 15, 2019August 31, 2025KADDURAH-DAOUK, RIMA Freporter.nih.gov
Reversing Immune Dysfunction for HIV-1 EradicationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$20,001,273August 16, 2021October 31, 2026CHANDA, SUMIT Kreporter.nih.gov
South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)NIHNational Institute of General Medical Sciences2021 to 2025$19,943,827September 30, 2001August 31, 2026GOLDSMITH, EDIE Creporter.nih.gov
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyNIHOffice of the Director, National Institutes of Health2021 to 2025$19,147,537September 21, 2016May 31, 2030KARAGAS, MARGARET RITAreporter.nih.gov
Optimization of Antibiotics in Mothers and their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic AnalysesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$17,176,139September 10, 2021July 31, 2026TREMOULET, ADRIANA Hreporter.nih.gov
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$15,678,563April 1, 2019September 30, 2026FRENCH, AUDREYreporter.nih.gov
Life Course Cancer Epidemiology Cohort in WomenNIHNational Cancer Institute2021 to 2025$15,280,631June 1, 2013August 31, 2028ELIASSEN, A. HEATHERreporter.nih.gov
Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategiesNIHNational Institute on Aging2022 to 2025$14,689,794September 15, 2019December 31, 2026PERLS, THOMAS Treporter.nih.gov
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyNIHOffice of the Director, National Institutes of Health2023 to 2024$14,260,643September 21, 2016May 31, 2025KARAGAS, MARGARET RITAreporter.nih.gov
MACS/WIHS -CCSNIHNational Heart, Lung, and Blood Institute2021 to 2025$12,990,830April 1, 2019September 30, 2026ALCAIDE, MARIA LUISAreporter.nih.gov
Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,773,513January 17, 2018December 31, 2027WUNDERINK, RICHARD Greporter.nih.gov
Functional Microbiomics, Inflammation and PathogenicityNIHNational Institute of General Medical Sciences2021 to 2025$12,492,994March 1, 2018February 29, 2028LAMONT, RICHARD Jreporter.nih.gov
Trans-omics Integration of Multi-omics Studies for OsteoporosisNIHNational Institute on Aging2021 to 2025$12,202,183September 15, 2017June 30, 2027DENG, HONG-WENreporter.nih.gov
Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersNIHNational Institute of Mental Health2021 to 2025$11,595,410May 22, 2018May 31, 2028LUBY, JOAN L.reporter.nih.gov
Kynurenine accumulation drives loss of muscle and bone function with agingNIHNational Institute on Aging2021 to 2025$11,563,609May 1, 2011May 31, 2027ISALES, CARLOS M.reporter.nih.gov
California Partnership for Personalized NutritionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$11,224,088December 10, 2021November 30, 2026ADAMS, SEAN HARRISONreporter.nih.gov
The DUST Center: Hazardous Dust in Drylands - Exposure, Health Impacts, and MitigationNIHNational Institute of Environmental Health Sciences2021 to 2025$11,160,526April 1, 1997January 31, 2030DING, XINXINreporter.nih.gov
The UCSD Microbiome and Metagenomics CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$10,609,774December 23, 2021November 30, 2026GILBERT, JACK ANTHONYreporter.nih.gov
Nutrition Precision Health for All of Us (Chicago Center)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$10,228,129December 10, 2021November 30, 2026VAN HORN, LINDA VERNERreporter.nih.gov
Determining the mechanism of pks+ E.coli-associated carcinogenesis in early onset colorectal cancer.NIHNational Cancer Institute2022 to 2025$9,558,240September 20, 2022August 31, 2027O'REILLY, EILEEN MARYreporter.nih.gov
Tissue destruction and healing in Celiac DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$9,512,977September 15, 2022July 31, 2027JABRI, BANAreporter.nih.gov
Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyNIHNational Cancer Institute2021 to 2025$9,251,154September 19, 2016August 31, 2026ULRICH, CORNELIA Mreporter.nih.gov
The Mutant Mouse Resource and Research Center at the University of MissouriNIHOffice of the Director, National Institutes of Health2021 to 2025$8,888,200May 1, 2000February 28, 2030AMOS-LANDGRAF, JAMESreporter.nih.gov
Statistical Methods for Integrative Genomics in CancerNIHNational Cancer Institute2021 to 2025$8,721,062July 1, 2016August 31, 2027GAUDERMAN, WILLIAM JAMESreporter.nih.gov
Nebraska Center for the Prevention of Obesity Diseases through Dietary MoleculesNIHNational Institute of General Medical Sciences2021 to 2024$8,657,651August 5, 2014May 31, 2025ZEMPLENI, JANOSreporter.nih.gov
Microbiome, Metabolites, and Alcohol in HIV to Reduce CVD (META HIV CVD)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,561,222September 10, 2021August 31, 2026FREIBERG, MATTHEW Sreporter.nih.gov
Southern Community Cohort StudyNIHNational Cancer Institute2021 to 2025$8,346,621July 21, 2016June 30, 2027ZHENG, WEIreporter.nih.gov
Human Biomimetics for Mucosal InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,059,968March 15, 2015May 31, 2027ESTES, MARY KOLBreporter.nih.gov
DartCF: The Dartmouth Cystic Fibrosis Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,832,026July 1, 2018August 31, 2030MADDEN, DEAN Rreporter.nih.gov
Microbial Chemical Sensing and Host ResponsesNIHNational Institute of General Medical Sciences2021 to 2025$7,729,035April 1, 2021June 30, 2026CRAWFORD, JASON MICHAELreporter.nih.gov
Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeNIHNational Cancer Institute2022 to 2025$7,696,898September 20, 2022August 31, 2027GRADY, WILLIAM MALLORYreporter.nih.gov
Small RNAs as Novel Modulators of Microbe-Host InteractionsNIHNational Center for Complementary & Integrative Health2021 to 2025$7,525,895September 1, 2021April 30, 2027GITAI, ZEMERreporter.nih.gov
Interactions Between the Microbiome, Immunity and Respiratory Health in Traditional Agrarian and Suburban childrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,471,626February 1, 2013February 29, 2028GERN, JAMES E.reporter.nih.gov
The Louisiana Clinical Center of Nutrition for Precision Health (LA-NPH)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$7,341,823December 10, 2021November 30, 2026RAVUSSIN, ERICreporter.nih.gov
Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$7,269,328March 15, 2023February 29, 2028DULAI, PARAMBIR SINGHreporter.nih.gov
Integrative Multidisciplinary Discovery Platform to Unlock Marine Natural Products Therapeutic OpportunitiesNIHNational Institute of General Medical Sciences2022 to 2025$7,069,063August 1, 2022July 31, 2027LUESCH, HENDRIKreporter.nih.gov
The oral environment in food allergy development (ONEIDA)NIHNational Institute of Allergy and Infectious Diseases2025$6,732,986August 1, 2025June 30, 2029BUNYAVANICH, SUPINDAreporter.nih.gov
A Foundation for the Oral Microbiome and MetagenomeNIHNational Institute of Dental & Craniofacial Research2021 to 2025$6,653,092April 1, 2006March 31, 2027MARK WELCH, JESSICA LEIGHreporter.nih.gov
Integrated Epithelial and Muscosal BiologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,598,874September 1, 1997June 16, 2026LENCER, WAYNE Ireporter.nih.gov
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,503,998August 14, 2020May 31, 2027NADEAU, KARI C.reporter.nih.gov
Mechanisms of Fecal Microbiota Transplant Protection from Recurrent C. difficileNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,326,957July 24, 2020June 30, 2029PETRI, WILLIAM Areporter.nih.gov
Prenatal Exposures and Child Health Outcomes: A Statewide StudyNIHOffice of the Director, National Institutes of Health2021 to 2023$6,156,799September 21, 2016August 31, 2023KERVER, JEAN MARIEreporter.nih.gov
Host and microbial basis of human ulcerative colitis and pouchitis: Identification, role, mechanisms, and resource development of host susceptibility and pathobiont factorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$6,122,586September 1, 2019May 31, 2025CHANG, EUGENE Breporter.nih.gov
A universal pipeline for functional characterization of the human microbiota at a massive scaleNIHNational Institute of General Medical Sciences2021 to 2024$6,002,443April 1, 2020March 31, 2026BUIE, CULLEN RICHARDreporter.nih.gov
Genetic Control of Metabolic Flux in Response to DietNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$5,939,998September 17, 2020June 30, 2026ATTIE, ALAN Dreporter.nih.gov
Novel Reengineered Microbiome-based Biologic Therapy to Treat Cognitive and Behavioral Symptoms of Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2022 to 2025$5,896,816August 15, 2022May 31, 2027KANTHASAMY, ANUMANTHA GOUNDERreporter.nih.gov
High-Dimensional Immune Monitoring of NCI-Supported Immunotherapy TrialsNIHNational Cancer Institute2023 to 2025$5,867,691September 30, 2017June 30, 2028GNJATIC, SACHAreporter.nih.gov
Identifying Microbial, Epithelial and Immune Cell Interactions that Mediate Mucosal Homeostasis and Determine IBD PhenotypesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$5,810,225September 19, 2013June 30, 2025SARTOR, RYAN Breporter.nih.gov
Overcoming resistance to anti-PD1 immunotherapyNIHNational Cancer Institute2021 to 2025$5,629,363December 7, 2016August 31, 2030GAJEWSKI, THOMAS Freporter.nih.gov
Mutographs differentiating the inheritance and temporal onset of multiple myelomaNIHNational Cancer Institute2021 to 2025$5,575,548August 11, 2021July 31, 2026MORGAN, GARETH JOHNreporter.nih.gov
Cervical, Anal & Oral HPV Persistence/Adolescent GirlsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,549,203May 15, 2007January 31, 2028DIAZ, ANGELAreporter.nih.gov
Effects of Intermittent Energy Restriction on Intra-Abdominal Fat and the Gut Microbiome: A Randomized TrialNIHNational Cancer Institute2021 to 2025$5,478,236September 22, 2021August 31, 2026LE MARCHAND, LOICreporter.nih.gov
Evaluation of doxycycline post-exposure prophylaxis to reduce sexually transmitted infections in PrEP users and HIV-infected men who have sex with menNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$5,430,840April 12, 2019March 31, 2025LUETKEMEYER, ANNE FREYreporter.nih.gov
Determinants of inception of inflammation in inflammatory bowel diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$5,397,834August 24, 2021May 31, 2027ANANTHAKRISHNAN, ASHWIN Nreporter.nih.gov
Novel polymeric materials with improved durability in the oral environment: tailoring responses to host and bacterial enzymes with anti-proteolytic and ecology-based antimicrobial approaches.NIHNational Institute of Dental & Craniofacial Research2021 to 2025$5,397,226September 1, 2019June 30, 2027PFEIFER, CARMEM S.reporter.nih.gov
Gut Microbiome and Individual Differences in Lumbosacral Radicular PainNIHNational Center for Complementary & Integrative Health2025$5,318,433August 15, 2025July 31, 2029SHEN, SHIQIANreporter.nih.gov
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaNIHOffice of the Director, National Institutes of Health2021 to 2022$5,260,253September 21, 2016August 31, 2024WEISS, SCOTT Treporter.nih.gov
Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$5,235,383September 18, 2019June 30, 2025WANG, DAVIDreporter.nih.gov
Skin microbes and development of allergic diseaseNIHNational Institute of Allergy and Infectious Diseases2025$5,176,858September 5, 2025August 31, 2029GALLO, RICHARD Lreporter.nih.gov
Fecal Microbiota Transplantation and Fiber for the Treatment of Graft-versus-host Disease After Hematopoietic Cell TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$5,128,451September 1, 2023June 30, 2027FREDRICKS, DAVID NEALreporter.nih.gov
Sialic acid analogs against multidrug-resistant gonorrheaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,099,184April 20, 2021March 31, 2027RAM, SANJAYreporter.nih.gov
Mucus-degrading intestinal bacteria and toxicities of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,032,505September 21, 2024July 31, 2029JENQ, ROBERTreporter.nih.gov
Reversing Immune Dysfunction for HIV-1 EradicationNIHNational Institute of Allergy and Infectious Diseases2021$5,001,807August 16, 2021October 31, 2021CHANDA, SUMIT Kreporter.nih.gov
Determinants of follicular helper T cell expansion in lupusNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,994,422July 8, 2020July 31, 2029MOREL, LAURENCEreporter.nih.gov
Bacteriophage-based approach for managing Shigella infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,946,719May 5, 2020April 30, 2026SULAKVELIDZE, ALEXANDERreporter.nih.gov
Advancing studies of polymicrobial diseases via streptococcal geneticsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,926,717September 1, 2018June 30, 2027MERRITT, JUSTINreporter.nih.gov
Microbial Programming of T-cell Migration from Gut to BrainNIHNational Institute of Allergy and Infectious Diseases2025$4,908,988July 14, 2025June 30, 2029WANG, ANDREWreporter.nih.gov
Precision Prevention Research ProgramNIHNational Cancer Institute2021 to 2025$4,849,798September 1, 2020August 31, 2027CHAN, ANDREW Treporter.nih.gov
Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in UgandaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,809,096April 15, 2020March 31, 2026DORSEY, MATTHEW Greporter.nih.gov
Algorithms and Software for the Assembly of Metagenomic DataNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,774,331March 21, 2013August 31, 2029POP, MIHAIreporter.nih.gov
Susceptibility Patterns for Grade C Periodontitis in Young IndividualsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$4,773,268September 22, 2022August 31, 2027SHADDOX, LUCIANA MACCHIONreporter.nih.gov
The Role of Chemical Exposures in Alzheimer's Disease (AD) and its TrajectoryNIHNational Institute on Aging2024 to 2025$4,768,289August 15, 2024July 31, 2029KADDURAH-DAOUK, RIMA Freporter.nih.gov
Development and Support of the Pathway Tools SoftwareNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,665,041May 12, 2021April 30, 2026KARP, PETER Dreporter.nih.gov
Defining Drivers of HPV-associated CarcinogenesisNIHNational Cancer Institute2021 to 2025$4,601,591August 1, 2017July 31, 2031LAMBERT, PAUL F.reporter.nih.gov
Intracellular Innate Immune Receptors in Cancer Suppression and ImmunotherapyNIHNational Cancer Institute2021 to 2025$4,541,273September 17, 2019August 31, 2026TING, JENNY Preporter.nih.gov
Povidone Iodine Efficacy Study (PIES)NIHNational Institute of Dental & Craniofacial Research2022 to 2025$4,268,923May 1, 2022April 30, 2027KOPYCKA-KEDZIERAWSKI, DOROTA T.reporter.nih.gov
Programmable benchtop bioreactors for scalable eco-evolutionary dynamics of the human microbiomeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,135,886June 10, 2022May 31, 2027KHALIL, AHMAD SAMIRreporter.nih.gov
High Resolution Characterization of Bacterial Epigenomes and MicrobiomeNIHNational Institute of General Medical Sciences2021 to 2025$4,119,232February 1, 2021January 31, 2026FANG, GANGreporter.nih.gov
The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targetsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$4,099,868September 21, 2021May 31, 2026GORDON, JEFFREY Ireporter.nih.gov
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican AmericanNIHNational Institute on Minority Health and Health Disparities2021 to 2025$4,084,828April 1, 2021December 31, 2026CHURCH, ARPANAreporter.nih.gov
Fragile Families: The Third GenerationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$4,015,455August 19, 2021April 30, 2027TEITLER, JULIEN Oreporter.nih.gov
Impact of chronic alcohol consumption on the functional and epigenetic landscapes of monocytes and their progenitorsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,998,523September 1, 2020August 31, 2029MESSAOUDI, ILHEMreporter.nih.gov
Is Obesity an Infectious Disease?: Gut bacterial and fungal translocation as an underappreciated driver of visceral adipose expansion.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,971,090September 30, 2021June 30, 2026DEVKOTA, SUZANNEreporter.nih.gov
A Longitudinal Study of Periodontal Infections and Alzheimer's Disease: The WHICAP Ancillary Study of Oral HealthNIHNational Institute on Aging2021 to 2025$3,954,825September 30, 2021June 30, 2027NOBLE, JAMES MCCALLUMreporter.nih.gov
Gut barrier function in Alzheimer’s diseaseNIHNational Institute on Aging2021 to 2025$3,945,245February 15, 2021January 31, 2026BENDLIN, BARBARA BRIGITTAreporter.nih.gov
Food Timing to Mitigate Adverse Consequences of Night WorkNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,943,217July 1, 2021June 30, 2027SCHEER, FRANK Areporter.nih.gov
Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHSNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,935,193February 1, 2022January 31, 2027XAVIER, RAMNIK Jreporter.nih.gov
The Center for High Content Functional Annotation of Natural ProductsNIHNational Center for Complementary & Integrative Health2021 to 2024$3,906,784September 1, 2015June 30, 2025MACMILLAN, JOHN Breporter.nih.gov
ELLIPSS: ELucidating the Landscape of Immunoendotypes in Psoriatic Skin and SynoviumNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,900,002March 21, 2022December 31, 2026RITCHLIN, CHRISTOPHER TREVORreporter.nih.gov
Trial of Human Milk Oligosaccharide-based synbiotics for HIV-exposed uninfected childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,899,337June 1, 2021May 31, 2027SHIVAKOTI, RUPAKreporter.nih.gov
Influence of HIV infection on vaginal virome and risk of preterm birth in pregnant South African womenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,895,544September 9, 2021July 31, 2027JASPAN, HEATHER BERYLreporter.nih.gov
Dietary and synbiotic strategy to limit gut microbiome dysbiosis and protect against Clostridioides difficile infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,880,251April 23, 2021March 31, 2027LOZUPONE, CATHERINEreporter.nih.gov
Autoimmune Drivers and Protectors Team Science (ADAPTS)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,860,822March 1, 2023February 29, 2028JAMES, JUDITH Areporter.nih.gov
Mechanisms and pathophysiologic impact of claudin-2 modulationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,845,865September 29, 2001June 30, 2028TURNER, JERROLD R.reporter.nih.gov
Population Genomic Analysis of Gut Microbial Colonization in Premature InfantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,825,244July 15, 2011June 30, 2026BANFIELD, JILLIANreporter.nih.gov
Impact of early-life perturbations on pediatric microbiome maturationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,815,792June 8, 2021June 23, 2026DANTAS, GAUTAMreporter.nih.gov
The Gut Microbiome and Personalized Mediterranean Diet Interventions for Cardiometabolic Disease PreventionNIHNational Institute of Nursing Research2021 to 2025$3,777,491September 23, 2021June 30, 2027WANG, DONGreporter.nih.gov
Commensal microbiome impact on CD4 T cell lymphopenia in HIV-1 infectionNIHNational Institute on Aging2022 to 2025$3,776,712September 15, 2022May 31, 2027YOUNES, SOUHEIL ANTOINEreporter.nih.gov
Preventing dental caries through targeted treatment of acid-producing bacteriaNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,746,349September 1, 2021August 31, 2026SUN, JIRUNreporter.nih.gov
Omics Data Generation Center (ODGC) for the Acute to Chronic Pain Signatures (A2CPS) ProgramNIHNational Institute on Drug Abuse2021 to 2025$3,741,527September 1, 2019July 31, 2027LAURENT, LOUISE CHANGreporter.nih.gov
Skin microbiome contributions to the pathogenesis of cutaneous leishmaniasisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,738,057March 4, 2019April 30, 2029SCOTT, PHILLIPreporter.nih.gov
Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental InterventionsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,727,321April 13, 2021March 31, 2027KIM, AMY Sreporter.nih.gov
Novel Determinants for Progression of Non-Alcoholic Fatty Liver Disease to Hepatocellular Carcinoma and Other Health OutcomesNIHNational Cancer Institute2021 to 2025$3,678,371September 7, 2021August 31, 2026YUAN, JIAN-MINreporter.nih.gov
Role of the Intestinal Microbiota in ALSNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,664,593January 15, 2021December 31, 2025WEINER, HOWARD Lreporter.nih.gov
Biopsychosocial Phenotypes and Potential Mechanisms in CHARTERNIHNational Institute of Mental Health2021 to 2025$3,655,824December 8, 2020October 31, 2026LETENDRE, SCOTT Lreporter.nih.gov
HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic studyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,646,054April 15, 2021March 31, 2027YOTEBIENG, MARCELreporter.nih.gov
A randomized, double-blind, multi-center comparative effectiveness study of spironolactone versus doxycycline hyclate for the treatment of acne in womenNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,635,308August 17, 2021July 31, 2027MARGOLIS, DAVID JOELreporter.nih.gov
Reserve against Disability in Early Multiple Sclerosis (RADIEMS) Longitudinal Cohort StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,629,278July 11, 2016July 31, 2026SUMOWSKI, JAMES FRANCISreporter.nih.gov
Biofilm Elimination and Caries Prevention using Multifunctional NanocatalystsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,608,276December 9, 2016August 31, 2027KOO, HYUNreporter.nih.gov
A large scale investigation of the vaginal metagenome and metabolome and their role in spontaneous preterm birthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,589,881August 3, 2021July 31, 2027KOREM, TALreporter.nih.gov
Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-RenewalNIHNational Cancer Institute2021 to 2025$3,585,446July 1, 2010June 30, 2027NAKAGAWA, MAYUMIreporter.nih.gov
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIVNIHNational Institute on Drug Abuse2022 to 2025$3,584,464June 15, 2022March 31, 2027ELLIS, RONALD J.reporter.nih.gov
A Transdisciplinary Approach to Investigating Metabolic Dysregulation in Obese Parent and Child Dyads and Risk of Colorectal CancerNIHNational Cancer Institute2022 to 2025$3,558,479August 16, 2022July 31, 2028HEBERT, JAMES Rreporter.nih.gov
Targeting the Intestinal Mucosa and Microbiome to Prevent Neonatal Late-onset SepsisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,526,115August 1, 2021July 31, 2027WEAVER, CASEY Treporter.nih.gov
Clinical Study of STI Screening to Prevent Adverse Birth and Newborn OutcomesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,525,168January 7, 2020December 31, 2025KLAUSNER, JEFFREY DAVIDreporter.nih.gov
Towards Precision Nutrition for Alzheimer's Dementia Prevention: A Prospective Study of Dietary Patterns, the Gut Microbiome and Cognitive FunctionNIHNational Institute on Aging2022 to 2025$3,513,490June 1, 2022March 31, 2027WANG, DONGreporter.nih.gov
Control of intestinal innate immunity by the commensal microbiota in a model hostNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,511,902September 24, 2021August 31, 2027WATNICK, PAULA Ireporter.nih.gov
Unraveling gut-microbiome-brain interactions in neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2025$3,503,497September 16, 2021June 30, 2027SAHIN, ERGUNreporter.nih.gov
Spatial Organization of the Oral MicrobiomeNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,495,105September 3, 2012August 31, 2028MARK WELCH, JESSICA LEIGHreporter.nih.gov
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,482,713August 14, 2020January 13, 2023NADEAU, KARI C.reporter.nih.gov
Personalized Dietary Management in Type 2 DiabetesNIHNational Institute of Nursing Research2021 to 2025$3,459,318January 15, 2021November 30, 2026POPP, COLLIN JEFFREYreporter.nih.gov
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,455,616February 11, 2020January 31, 2026ROBINSON-PAPP, JESSICAreporter.nih.gov
Immunobiology of Lung Injury and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,455,443January 21, 2019December 31, 2024MOORE, BETHANY B.reporter.nih.gov
Epidemiologic and molecular basis of the gut-urinary tract axis in urinary tract infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,416,719June 12, 2020July 31, 2030HULTGREN, SCOTT J.reporter.nih.gov
Studies on gut microbiome-joint connections in arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,412,637April 1, 2021February 28, 2027ZUSCIK, MICHAEL Jreporter.nih.gov
Systematic characterization of bioactive molecules from the human microbiomeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,412,560June 16, 2022May 31, 2027ABOU DONIA, MOHAMEDreporter.nih.gov
Characterization of Mucosal LymphocytesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,410,819September 30, 1992June 30, 2029BLUMBERG, RICHARD Sreporter.nih.gov
Microbiota-derived metabolites and the regulation of host immunity and inflammationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,409,847June 14, 2022May 31, 2027ARTIS, DAVIDreporter.nih.gov
National Gnotobiotic Resource CenterNIHOffice of the Director, National Institutes of Health2021 to 2025$3,407,181July 1, 2003June 30, 2029SARTOR, RYAN Breporter.nih.gov
Microbial Community Disruption Following Topical Antimicrobial Application in Staphylococcus aureus-Affected HouseholdsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,400,860May 19, 2021April 30, 2027FRITZ, STEPHANIE ANNreporter.nih.gov
The Gut Microbiome Brain Axis and Preterm InfantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,393,142May 5, 2021January 31, 2026CLAUD, ERIKA Creporter.nih.gov
Commensal control of C. difficile virulenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,372,908February 1, 2021January 31, 2027BRY, LYNNreporter.nih.gov
Multi-method investigation and characterization of the ocular microbiomeNIHNational Eye Institute2023 to 2025$3,357,381July 1, 2023June 30, 2027DE PAIVA, CINTIA S.reporter.nih.gov
Gamma delta T cells promote inflammation in aviremic HIV infection and normal agingNIHNational Institute on Aging2021 to 2024$3,347,408August 15, 2020May 31, 2026SNYDER-CAPPIONE, JENNIFER Ereporter.nih.gov
Viral respiratory infections in a tracheostomy cohort: Microbiome-host interplayNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,346,417September 21, 2022July 31, 2027MANSBACH, JONATHAN Mreporter.nih.gov
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,343,705April 1, 2021March 31, 2026SCHRAMM, VERN L.reporter.nih.gov
Periodontitis Role in Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,340,009September 1, 2025August 31, 2029THUMBIGERE-MATH, VIVEKreporter.nih.gov
Vaginal microbiota transplant to promote Lactobacillus-dominant cervicovaginal communitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,339,208September 20, 2021August 31, 2027MITCHELL, CAROLINE Mreporter.nih.gov
A novel mechanism of virulence control in Porphyromonas gingivalisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,328,558July 1, 2021June 30, 2027FRIAS-LOPEZ, JORGEreporter.nih.gov
Socioecological Determinants of Immunoepigenetic Signatures of Diabetes Risk in Indigenous CommunitiesNIHNational Institute on Minority Health and Health Disparities2021 to 2025$3,326,115July 28, 2021April 30, 2027MAUNAKEA, ALIKA KEOLAOKALANIreporter.nih.gov
Mapping host-microbe-metabolite interactions in 3D to find diet-derived enhancers of immunityNIHNational Center for Complementary & Integrative Health2021 to 2023$3,318,000September 30, 2019July 31, 2024KNIGHT, ROBreporter.nih.gov
Defining bacterial members of the ocular surface microbiome and assessing stability over timeNIHNational Eye Institute2023 to 2025$3,305,844July 1, 2023June 30, 2027ST LEGER, ANTHONY Jreporter.nih.gov
"A microbiome-dependent bile acid metabolite improves type 2 diabetes."NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,304,418January 8, 2021December 31, 2026SHEU, ERIC GARLANDreporter.nih.gov
The Influence Of Gut Microbiota Stability In Inflammatory Bowel DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,299,380March 4, 2019February 28, 2027FAITH, JEREMIAH JAMESreporter.nih.gov
Engineering Transmissible HealthNIHNational Institute of General Medical Sciences2021 to 2022$3,290,462August 6, 2018July 31, 2024GUILLEMIN, KAREN Jreporter.nih.gov
Impact of HIV, oral microbiome and mycobiome on oral HPV persistenceNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,289,768September 1, 2022August 31, 2027BURK, ROBERT Dreporter.nih.gov
Causes and consequences of interpersonal microbial variationNIHNational Institute of General Medical Sciences2021 to 2025$3,283,079June 10, 2016May 31, 2026GOODMAN, ANDREW Lreporter.nih.gov
Diet transformation by the microbiome and its impact on bacterial infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,277,659August 16, 2022May 31, 2027GOODMAN, ANDREW Lreporter.nih.gov
Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,276,651September 23, 2021July 31, 2027DASARATHY, SRINIVASANreporter.nih.gov
The Role of Secondary Bile Acids in Gastro-Esophageal NeoplasiaNIHNational Cancer Institute2022 to 2025$3,273,998September 1, 2022August 31, 2027ABRAMS, JULIANreporter.nih.gov
Predictors of Antiretroviral Immunereconstitution Bone Loss - the Gut and the MicrobiomeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,266,890September 21, 2021August 31, 2026WEITZMANN, MERVYN NEALEreporter.nih.gov
Longitudinal Study of Early NAFLD Progression and the Gut Microbiome in Asian Americans, Native Hawaiians and WhitesNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,263,901September 26, 2022June 30, 2027LIM, UNHEEreporter.nih.gov
Decoding mutualistic microbiota-B cell interactions in the HIV-1-infected gut: impact on immunological non-respondersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,259,183May 7, 2020April 30, 2026MEHANDRU, SAURABHreporter.nih.gov
Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significanceNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,257,323August 20, 2021June 30, 2026NAYOR, MATTHEW G.reporter.nih.gov
Indoles from commensal microbiota promote mobility during agingNIHNational Institute on Aging2025$3,251,767September 1, 2025August 31, 2029KALMAN, DANIELreporter.nih.gov
New Jersey ECHONIHOffice of the Director, National Institutes of Health2023 to 2024$3,229,703September 1, 2023May 31, 2025BARRETT, EMILY Sreporter.nih.gov
Glycomic Modulation of Gut Microbiome During HIV InfectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,228,597December 24, 2019November 30, 2025ABDEL MOHSEN, MOHAMEDreporter.nih.gov
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonNIHOffice of the Director, National Institutes of Health2021 to 2025$3,222,498September 21, 2016May 31, 2030CAMARGO, CARLOS ARTUROreporter.nih.gov
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,218,917August 15, 2015June 30, 2026JENQ, ROBERTreporter.nih.gov
Gut Microbiota Modulation of Chikungunya Virus Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,216,725April 1, 2021March 31, 2027DIAMOND, MICHAEL Sreporter.nih.gov
B cell clonal selection in gut-associated germinal centersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,203,164September 17, 2020August 31, 2025VICTORA, GABRIEL Dreporter.nih.gov
Local microbiota signatures of pro-tumor immunity and checkpoint inhibition susceptibility in lung cancerNIHNational Cancer Institute2021 to 2025$3,194,826January 1, 2025December 31, 2026SEGAL, LEOPOLDO NICOLASreporter.nih.gov
Understand biological factors underlying early childhood caries disparity from the oral microbiome in early infancyNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,190,415May 1, 2022January 31, 2027XIAO, JINreporter.nih.gov
Impact of ocular microbiome, immune response and Chlamydiae on trachoma following MDANIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,190,228July 1, 2022June 30, 2027DEAN, DEBORAH ANNEreporter.nih.gov
Alanyl-glutamine supplementation of standard treatment for C. difficile infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,184,912July 13, 2020June 30, 2026WARREN, CIRLE ALCANTARAreporter.nih.gov
The role of gut microbes and microbial derived metabolites in the development of type 2 diabetes in humansNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,184,687August 2, 2021June 30, 2027MAJITHIA, AMITreporter.nih.gov
Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza responseNIHNational Institute of Allergy and Infectious Diseases2025$3,182,827August 19, 2025July 31, 2029OH, JULIAreporter.nih.gov
Residential Greenness, Airway Microbiome,and Incident Childhood AsthmaNIHNational Institute of Environmental Health Sciences2025$3,181,155September 18, 2025September 17, 2029ZHU, ZHAOZHONGreporter.nih.gov
Natural History of C. trachomatis urogenital and rectal infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,179,786March 20, 2020February 28, 2026DEAN, DEBORAH ANNEreporter.nih.gov
Is the gut important in multiple joint osteoarthritis? A multimodal investigation in humans and pet dogsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,176,745August 5, 2022June 30, 2027NELSON, AMANDA Ereporter.nih.gov
A life course perspective on gut microbiome aging and health in a non-human primate modelNIHNational Institute on Aging2021 to 2025$3,173,432April 15, 2021January 31, 2027ARCHIE, ELIZABETHreporter.nih.gov
Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)NIHNational Institute of Mental Health2023 to 2025$3,165,352September 15, 2021August 31, 2026CARRICO, ADAM WAYNEreporter.nih.gov
Immune Development Across the Life Course: Integrating Exposures and Multi-Omics in the Boston Birth CohortNIHNational Institute of Environmental Health Sciences2022 to 2025$3,158,931September 15, 2022June 30, 2027WANG, XIAOBINreporter.nih.gov
Identification and Characterization of Microbial Metabolites in ImmunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,152,946May 26, 2022April 30, 2027XAVIER, RAMNIK Jreporter.nih.gov
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer RiskNIHNational Cancer Institute2021 to 2025$3,149,705January 15, 2021December 31, 2026FITZGIBBON, MARIAN L.reporter.nih.gov
Vibrio cholerae antinitrosative stress defenses and gut microbiome interactionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,145,639September 23, 2020August 31, 2025ZHU, JUNreporter.nih.gov
Microbiome, Environment, and Parkinsons disease (MEP) PESTICIDE EXPOSURES AND THE GUT MICROBIOME IN PARKINSONS DISEASENIHNational Institute of Environmental Health Sciences2021 to 2025$3,143,396August 15, 2020June 30, 2026RITZ, BEATE R.reporter.nih.gov
Relationship of fungal translocation, inflammation, and pulmonary function in HIVNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,142,352July 10, 2022May 31, 2027METHE, BARBARAreporter.nih.gov
Engineering Native E. coli to Detect, Report, and Treat Colorectal CancerNIHNational Cancer Institute2021 to 2025$3,135,340September 21, 2021August 31, 2026ZARRINPAR, AMIRreporter.nih.gov
Oral microbiome and periodontal diseases in oral HPV infection among people living with HIVNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,134,374August 11, 2022July 31, 2027XIAO, CANHUAreporter.nih.gov
Cervicovaginal microbiome, mucosal immunity, and pathogen factors that contribute to spontaneous clearance of Chlamydia trachomatisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,127,515June 1, 2022May 31, 2027BROTMAN, REBECCA M.reporter.nih.gov
Microbiota, Metabolites, and Colon NeoplasiaNIHNational Cancer Institute2021 to 2025$3,124,761May 1, 2021April 30, 2027ROSENBERG, DANIEL WILLIAMreporter.nih.gov
Structural and functional studies of colibactinNIHNational Cancer Institute2021 to 2025$3,124,458December 11, 2017February 29, 2028HERZON, SETH B.reporter.nih.gov
Intestinal microbiota-mediated rotavirus vaccine failureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,123,686September 19, 2022July 31, 2027GEWIRTZ, ANDREW Treporter.nih.gov
Innate lymphoid cell regulation of the host-microbiota interactions in cancerNIHNational Cancer Institute2022 to 2025$3,122,275September 20, 2022August 31, 2027SONNENBERG, GREGORY Freporter.nih.gov
MOM2CHild Study: Leveraging systems biology toward discoveries in Maternal Obesity, Milk, and Translation To Child HealthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$3,113,115August 23, 2022May 31, 2027MORROW, ARDYTHE Lreporter.nih.gov
Microbiota-immune interactions that promote intestinal homeostasisNIHNational Center for Complementary & Integrative Health2021 to 2025$3,111,145June 15, 2021May 31, 2026ROUND, JUNE LOUISEreporter.nih.gov
Determinants of H. influenzae Virulence in Otitis MediaNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,109,258September 30, 1999December 31, 2026GOODMAN, STEVEN Dreporter.nih.gov
The Role of the Microbiome and Notch Signaling in Esophageal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$3,108,327January 1, 2021December 31, 2026ABRAMS, JULIANreporter.nih.gov
Impact of metabolic programing of T cells from the GI tract and related tissues on HIV reservoir seeding, maintenance and reactivationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,091,749September 30, 2021July 31, 2027APETREI, CRISTIANreporter.nih.gov
MAEVE: Microbiota mediated flavonoid metabolites for cognitive healthNIHNational Institute on Aging2024 to 2025$3,084,260July 15, 2024June 30, 2029CHURCH, ARPANAreporter.nih.gov
Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogenNIHNational Cancer Institute2021 to 2025$3,068,738September 13, 2021August 31, 2027KHAZAIE, KHASHAYARSHAreporter.nih.gov
Detection of pathogen infection by monitoring host cell membrane dynamicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,065,177September 22, 2021August 31, 2026PUKKILA-WORLEY, READreporter.nih.gov
The Role of the Gut Microbiome and Short Chain Fatty Acids in the Regulation of Inflammation and Neuropsychological Symptoms in Patients with Head and Neck CancerNIHNational Institute of Nursing Research2022 to 2025$3,064,029May 9, 2022February 28, 2027XIAO, CANHUAreporter.nih.gov
The Gut Microbiota in Metabolic Surgery: A Multi-Ethnic, Multi-Omic, Longitudinal StudyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,059,645February 5, 2021January 31, 2027YU, DANXIAreporter.nih.gov
Development of novel anti-Neisseria gonorrhoeae therapeutic agentsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,055,792August 12, 2022July 31, 2027FLAHERTY, DANIEL PATRICKreporter.nih.gov
Mechanism of action for the epithelial-specific ER stress sensor IRE1β in regulating intestinal homeostasis and host defenseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,050,147September 1, 1993March 31, 2026LENCER, WAYNE Ireporter.nih.gov
Building the foundations of commensal vaccinesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,047,222September 23, 2022August 31, 2027FISCHBACH, MICHAEL ANDREWreporter.nih.gov
Influence of maternal virome and HIV status on infant gut virome, growth and immunityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,044,222September 21, 2020August 31, 2025JASPAN, HEATHER BERYLreporter.nih.gov
3D-bioprinting of sustained- and phased-release antibiotic and probiotic scaffolds to treat bacterial vaginosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,595February 25, 2022January 31, 2028FRIEBOES, HERMANNreporter.nih.gov
Time restricted feeding versus daily calorie restriction: Effect on body weight, metabolic risk, and the gut microbiomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,028,553September 14, 2021July 31, 2027VARADY, KRISTA AMYreporter.nih.gov
Dissecting the pathogenesis and outcomes of PSC using multi-omics by studying the exposome and genomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$3,027,125September 1, 2018July 31, 2025LAZARIDIS, KONSTANTINOS Nreporter.nih.gov
Metapangenomics of the Oral MicrobiomeNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,025,869July 1, 2021June 30, 2027BORISY, GARY Greporter.nih.gov
Study the Treg-IL-27 axis in immune regulationNIHNational Institute of Allergy and Infectious Diseases2025$3,022,197July 8, 2025June 30, 2029LU, LI-FANreporter.nih.gov
Mechanistic basis of bacteriophages for the decolonization of vancomycin resistant enterococci in the intestineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,022,123September 14, 2018July 31, 2028DUERKOP, BRECK Areporter.nih.gov
Uncovering the rules of gut microbiome strain transmissionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,013,179January 20, 2020December 31, 2028FAITH, JEREMIAH JAMESreporter.nih.gov
Dietary Fiber-Microbiome Interactions: Elucidating Mechanisms to Suppress Multi-Drug Resistant Organisms in the Human GutNIHNational Institute of Allergy and Infectious Diseases2025$3,012,181September 10, 2025August 31, 2029VENTURELLI, OPHELIAreporter.nih.gov
Host and microbial risk factors of oral thrush in cancer patients receiving chemotherapyNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,008,274August 4, 2022May 31, 2027DIAZ, PATRICIAreporter.nih.gov
The impact of bacteriophage therapy on wound infection dynamicsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,006,418February 2, 2022January 31, 2027WOZNIAK, DANIEL Jreporter.nih.gov
CyberGut: towards personalized human-microbiome metabolic modeling for precision health and nutritionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,006,256July 1, 2022April 30, 2027GIBBONS, SEAN MICHAELreporter.nih.gov
A consortium facilitation, coordination, and data management center for the HVPNIHNational Heart, Lung, and Blood Institute2025$3,000,337January 15, 2025December 31, 2029WHITE, OWEN Rreporter.nih.gov
Improving diagnostic sensitivity for difficult-to-lyse microbial samples with nanodroplet technologyNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,995,731August 3, 2020April 30, 2026KASOJI, SANDEEPreporter.nih.gov
Bacterial biosensors for the prevention of gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$2,993,830May 18, 2020April 30, 2029HASTY, JEFF Mreporter.nih.gov
Targeting microbial dysbiosis in Food Allergy to restore toleranceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,989,996February 25, 2021January 31, 2026CHATILA, TALAL AMINEreporter.nih.gov
The microbiome and aging in Clostridioides difficile infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,979,948May 1, 2022April 30, 2026YOUNG, VINCENT Breporter.nih.gov
Rapid antimicrobial susceptibility testing directly from urine specimensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,974,719April 1, 2021March 31, 2024BURG, LAWRENCEreporter.nih.gov
The Role of Nasal Mucosal Immunity and Microbiome on the Frequent Exacerbation Phenotype of COPDNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,964,430May 8, 2021April 30, 2026DRUMMOND, MICHAEL BRADLEYreporter.nih.gov
Dietary Etiologies of Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,960,284December 1, 1985May 19, 2025RIMM, ERIC Breporter.nih.gov
Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)NIHNational Cancer Institute2021 to 2024$2,958,194July 15, 2020June 30, 2025CAPORASO, JAMES GREGORYreporter.nih.gov
Rapid AST through Metabolic Imaging at Single Cell LevelNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,949,272December 1, 2018June 30, 2027CHENG, JI-XINreporter.nih.gov
FabI Inhibitors as Potent, Gut Microbiome-Sparing AntibioticsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,933,391June 26, 2023May 31, 2028HERGENROTHER, PAULreporter.nih.gov
Intestinal CD4 T cell responses to dietary and microbial antigensNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,926,273January 1, 2013December 31, 2026MUCIDA, DANIEL Sreporter.nih.gov
Regulation and function of mucosal IgA immune responses to mycobiota in the gut.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,924,410June 1, 2021May 31, 2027ILIEV, ILIYAN DIMITROVreporter.nih.gov
NOVEL METABOLITE AND MICROBIOTA PATHWAYS FOR HYPERURICEMIA AND GOUTNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,924,301September 20, 2013February 28, 2027CHOI, HYON Kreporter.nih.gov
Anaerobic Manufacturing and Molecular Analytical Process Optimization to Support Clinical Development of Live Biotherapeutic ProductsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,921,132February 4, 2022April 30, 2025VALLADARES, RICARDOreporter.nih.gov
Commensal-specific T cell function in skin wound repairNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,918,975February 1, 2021April 30, 2026HARRISON, OLIVER JAMESreporter.nih.gov
A Novel Probiotic for the Treatment of Sjogren's SyndromeNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,918,422May 12, 2021April 30, 2026FANGER, GARYreporter.nih.gov
Deciphering the role of chemical signals in inflammation with open microfluidic functional assaysNIHNational Institute of General Medical Sciences2021 to 2025$2,917,209August 1, 2018July 31, 2028THEBERGE, ASHLEIGH BROOKSreporter.nih.gov
Investigating neurobehavioral consequences of COVID-19 related stressors on maternal mental health and infant developmentNIHNational Institute of Mental Health2021 to 2024$2,914,615June 1, 2021March 31, 2026BRITO, NATALIE HIROMIreporter.nih.gov
New Engineering Strategy for Harnessing Immune System against Head and Neck CancerNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,903,162July 1, 2021April 30, 2026MOON, JAMES J.reporter.nih.gov
Host and bacterial mechanisms governing Group B streptococcal persistence in the female genital tractNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,897,992March 3, 2021February 28, 2027DORAN, KELLY Sreporter.nih.gov
Role of CREM in Amebic Colitis and Inflammatory Bowel DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,896,698August 1, 1989December 31, 2027PETRI, WILLIAM Areporter.nih.gov
Enhancement of autoimmunity in type 1 diabetes by glutenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,890,025September 17, 2021August 31, 2027CHERVONSKY, ALEXANDER Vreporter.nih.gov
Antimicrobial Resistance and Horizontal Gene Transfer in the Human Gut Microbiome in Response to an AntibioticNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,871,429June 1, 2020May 31, 2026RELMAN, DAVID A.reporter.nih.gov
Gamma Delta T cell and microbial modulation to target chronic SIV-associated inflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,868,592July 15, 2022May 31, 2027ROUT, NAMITAreporter.nih.gov
Obstructive sleep apnea, the microbiome and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,867,397January 1, 2022December 31, 2025HADDAD, GABRIEL Greporter.nih.gov
Understanding and Harnessing Microbial Reprogramming to Combat Carcinogenic Colibactin in Colorectal CancerNIHNational Cancer Institute2025$2,864,671September 10, 2025August 31, 2029LI, JIAHEreporter.nih.gov
Gut microbiota and human malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,860,358July 1, 2020June 30, 2026SCHMIDT, NATHANreporter.nih.gov
Investigating the effect of oral microbiome on cognition in HIV-infected chronic cannabis usersNIHNational Institute on Drug Abuse2022 to 2025$2,858,390September 30, 2022July 31, 2027FITTING, SYLVIAreporter.nih.gov
Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,856,384June 1, 2022April 30, 2027JASPAN, HEATHER BERYLreporter.nih.gov
Baltimore Oral Epidemiology, Disease Effects, and HIV Evaluation Study (BEEHIVE)NIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,855,619August 1, 2020July 31, 2026MACEK, MARK Dreporter.nih.gov
Novel recombinant Rotavirus vaccine utilizing the probiotic microorganism Lactobacillus acidophilusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,850,503December 13, 2019November 30, 2025DEAN, GREGG Areporter.nih.gov
Childhood Allergy and the NeOnatal Environment (CANOE) ECHO Pediatric Follow-Up and New EnrollmentNIHOffice of the Director, National Institutes of Health2023 to 2024$2,848,939September 1, 2023May 31, 2025SINGH, ANNE MARIEreporter.nih.gov
Defining the Role of Enteric Nervous System Dysfunction in Gastrointestinal Motor and Sensory Abnormalities in Down SyndromeNIHNational Institute of Neurological Disorders and Stroke2023$2,837,478May 1, 2023April 30, 2026BELKIND-GERSON, JAIMEreporter.nih.gov
Absorption of vitamin B1 along the intestinal tract: Physiology, pathophysiology and cell biology aspectsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,831,663August 1, 1999December 31, 2025SAID, HAMID Mreporter.nih.gov
The Development of Gut Microbiota and Behavioral Inhibition in Childhood: The Role of Early Stress and Brain DevelopmentNIHNational Institute of Mental Health2021 to 2024$2,820,144September 18, 2020June 30, 2026PROPPER, CATHI BARBRAreporter.nih.gov
Molecular Mechanism of Virulence Regulation in Streptococcus PyogenesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,818,660June 7, 2021May 31, 2027KUMARASWAMI, MUTHIAHreporter.nih.gov
Bioinformatics Framework for Wastewater-based Surveillance of Infectious DiseasesNIHNational Library of Medicine2021 to 2022$2,817,521June 3, 2019May 31, 2024SCOTCH, MATTHEWreporter.nih.gov
Mechanistic pathways of the effects of human-animal interaction on depression and psychosocial stressNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,813,817April 1, 2020February 28, 2027SCHERNHAMMER, EVA Sreporter.nih.gov
The role of the intestinal microbiome in cancer immunotherapyNIHNational Cancer Institute2023 to 2025$2,811,009August 1, 2023July 31, 2030VAN DEN BRINK, MARCEL R Mreporter.nih.gov
Mechanism of microbiota-mediated potentiation of checkpoint blockade efficacy in lung cancerNIHNational Cancer Institute2021 to 2025$2,809,344August 1, 2021July 31, 2026LITTMAN, DANreporter.nih.gov
Milk-Omics: Systems Biology of Human Milk and Its Links to Maternal and Infant HealthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,806,298September 23, 2022August 31, 2027DEMERATH, ELLEN W.reporter.nih.gov
ATP-driven detection of foreign proteins triggers diverse mechanisms of cellular defense and phage-mediated counter defenseNIHNational Institute of General Medical Sciences2021 to 2025$2,805,764February 1, 2020April 30, 2030WIEDENHEFT, BLAKE Areporter.nih.gov
Impact of particle and ozone inhalation co-exposure on alveolar epithelial regenerationNIHNational Institute of Environmental Health Sciences2021 to 2024$2,799,613May 1, 2020February 28, 2026HUSSAIN, SALIKreporter.nih.gov
Micron-scale Spatial Metagenomic Mapping of Microbial Biogeography in the Gastrointestinal TractNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,799,544June 1, 2017May 31, 2028WANG, HARRIS Hreporter.nih.gov
Bacterial metabolites controlling Th17 and Treg cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,799,466September 1, 2016July 31, 2025HUH, JUN R.reporter.nih.gov
Neuro-immune interactions at the intestinal surfaceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,799,092April 1, 2024March 31, 2029MUCIDA, DANIEL Sreporter.nih.gov
Mechanisms of MRSA intestinal colonizationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,795,502January 17, 2020December 31, 2025SHOPSIN, BOreporter.nih.gov
Vertically transferred antibodies protect babies from Escherichia coli infectionNIHNational Institute of Allergy and Infectious Diseases2025$2,790,604September 11, 2025August 31, 2029WAY, SING SINGreporter.nih.gov
Targeting the Meta-organismal Butyrate Pathway to Prevent Arterial Restenosis after Vascular SurgeryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,787,567April 1, 2021March 31, 2027HO, KAREN J.reporter.nih.gov
Dietary influence on infant growth and the gut microbiotaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,783,406February 2, 2021August 15, 2024TANG, MINGHUAreporter.nih.gov
Role of RORgt+ (note: g: is gamma symbol) lymphocytes in Gut Tissue HomeostasisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,779,710August 1, 2021July 31, 2027ZHOU, LIANGreporter.nih.gov
Treating colon cancer by regulating intestinal immunity through microbial metabolismNIHNational Cancer Institute2021 to 2025$2,772,249June 1, 2021May 31, 2027ARPAIA, NICHOLASreporter.nih.gov
A prospective evaluation of the gut microbiome as a mediator of lymphoma treatment outcome and systemic immunityNIHNational Cancer Institute2022 to 2025$2,770,577February 24, 2022January 31, 2027DIEFENBACH, CATHERINE SIBYLreporter.nih.gov
The Discovery of Novel Metabolic Pathways for the Biosynthesis and Degradation of Complex Carbohydrates within the Human Gut MicrobiomeNIHNational Institute of General Medical Sciences2021 to 2025$2,770,488February 1, 2021January 31, 2027RAUSHEL, FRANK M.reporter.nih.gov
Elucidating the Role of Regulatory T cells in Establishing and Maintaining a Th2 Niche in SkinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,768,552July 10, 2020June 30, 2025ROSENBLUM, MICHAEL DAVIDreporter.nih.gov
Biobehavioral Factors and their Impact on Stress-Related Eating in ObesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,764,300September 21, 2021May 31, 2026ENGEL, SCOTT Greporter.nih.gov
Gut Flora metabolism of dietary carnitine and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,763,113August 1, 2010April 30, 2026HAZEN, STANLEY Lreporter.nih.gov
Environmental Chemical Impact on the Host-Microbiome InteractionNIHNational Institute of Environmental Health Sciences2023 to 2025$2,749,465June 13, 2023May 31, 2031PATTERSON, ANDREWreporter.nih.gov
Linking microbiome genetic variants with cardiovascular phenotypes in 50,000 individualsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,748,578August 1, 2022May 31, 2027POLLARD, KATHERINE S.reporter.nih.gov
Endoplasmic reticulum stress and intestinal inflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,747,810May 1, 2010March 31, 2030BLUMBERG, RICHARD Sreporter.nih.gov
Breathprinting as a window into gut microbiome chemoecologyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,742,643September 1, 2022June 30, 2027ODOM JOHN, AUDREY RAGANreporter.nih.gov
Mechanism of Colonization ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,739,660August 20, 2014March 31, 2026BAUMLER, ANDREAS Jreporter.nih.gov
Role of Notch-1/PLA2-IIA in oral dysbiosis, inflammation, and periodontal diseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,736,892August 1, 2021April 30, 2027GONZALEZ, OCTAVIO ALBERTOreporter.nih.gov
Gut microbiome effects on intestinal barrier function and metabolic syndrome in HIV positive men who have sex with menNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,735,326August 1, 2022May 31, 2027LOZUPONE, CATHERINEreporter.nih.gov
ECHO Renewal for the CANOE Study CohortNIHOffice of the Director, National Institutes of Health2023 to 2024$2,735,209September 1, 2023May 31, 2026HARTERT, TINA Vreporter.nih.gov
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT InterventionNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,727,333September 10, 2022July 31, 2027BARVE, SHIRISH Sreporter.nih.gov
Predicting and preventing drug metabolism by the human gut microbiomeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,718,950March 1, 2016July 31, 2026TURNBAUGH, PETER JAMESreporter.nih.gov
University of Minnesota Clinical Center for the Study of Pancreatic DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,713,570September 3, 2020June 30, 2030BELLIN, MELENA D.reporter.nih.gov
Molecular mapping of microbial communities at the host-pathogen interface by multi-modal 3-dimensional imaging mass spectrometryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,710,007September 19, 2018May 31, 2029SKAAR, ERIC Preporter.nih.gov
Aromatic Amino Acids, Microbiome-Generated Metabolites, and Incident Subclinical and Clinical CVD and MortalityNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,706,539July 1, 2017January 31, 2028MOZAFFARIAN, DARIUSHreporter.nih.gov
Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,705,917March 10, 2020February 28, 2026DE VLAMINCK, IWIJNreporter.nih.gov
Fecal Microbiota Transplant National RegistryNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,705,877August 4, 2016April 30, 2027WU, GARY D.reporter.nih.gov
Gut microbiome, enteric infections and child growth across a rurual urban gradientNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,701,254January 24, 2018December 31, 2025LEVY, KARENreporter.nih.gov
Mechanisms of alteration of gastrointestinal physiology by gut microbesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,700,677September 1, 2017June 30, 2027KASHYAP, PURNA Creporter.nih.gov
Dietary Regulation of Intestinal Inflammation and RepairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,700,479March 15, 2022January 31, 2027ARTIS, DAVIDreporter.nih.gov
Contribution of the Virome to HIV/AIDS pathogenesisNIHNational Institute on Drug Abuse2021 to 2024$2,697,396February 14, 2020May 31, 2026KORALNIK, IGOR J.reporter.nih.gov
Host-microbe interactions: Harnessing co-evolution to treat diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,693,600September 30, 2018July 31, 2024AYRES, JANELLE Sreporter.nih.gov
Functional Redundancy of Human Microbiome and its Implication in Fecal Microbiota TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,682,798August 15, 2019July 31, 2025LIU, YANG-YUreporter.nih.gov
Gut symbiotic microbiota-derived CD1d ligands and their immunomodulatory mechanismsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,675,501June 14, 2022May 31, 2027OH, SUNGWHAN Freporter.nih.gov
Link between early gut dysfunction and amyloid beta aggregation in Alzheimer's Disease related dementiaNIHNational Institute on Aging2021 to 2025$2,672,767June 1, 2021March 31, 2027GANESH, BHANU PRIYAreporter.nih.gov
Neurobiological and neurocognitive consequences of diverse microbiome functional trajectoriesNIHNational Institute of Mental Health2022 to 2025$2,670,235July 1, 2022May 31, 2027GILL, STEVEN R.reporter.nih.gov
Fiber-rich Foods to Treat Obesity and Prevent Colon CancerNIHNational Cancer Institute2021 to 2024$2,669,304July 15, 2020June 30, 2026HARTMAN, TERRYL J.reporter.nih.gov
Comprehensive Training Program in Oral BiologyNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,668,959July 1, 2011June 30, 2027LEMOS, JOSE Areporter.nih.gov
Investigating the Influences of Sleep‐Wake Patterns and Gut Microbiome Development in Infancy on Rapid Weight Gain, an Early Risk Factor for ObesityNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,668,382February 1, 2020January 31, 2026PETROV, MEGAN ELISEreporter.nih.gov
A high-performance and versatile technology for precision microbiome engineeringNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,652,300September 1, 2021May 31, 2026WANG, HARRIS Hreporter.nih.gov
Nutrigenetics and Nutrigenomics for Precision Weight-Loss Diet InterventionsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,646,037January 1, 2018April 30, 2027QI, LUreporter.nih.gov
Immunity to commensal papillomaviruses for cancer therapyNIHNational Cancer Institute2021 to 2025$2,645,679May 1, 2021April 30, 2027DEMEHRI, SHADMEHRreporter.nih.gov
Mindfulness meditation training for Irritable Bowel SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,643,486May 4, 2021April 30, 2026CRESWELL, JOHN DAVIDreporter.nih.gov
Microbial regulation of intestinal lipid metabolism and its physiological consequencesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,640,580December 3, 2021November 30, 2026RAWLS, JOHN Freporter.nih.gov
Vibrio fischeri as a Model for Bacterial ColonizationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,639,528December 1, 2001February 29, 2028MC FALL-NGAI, MARGARET Jreporter.nih.gov
Gut bacterial metallophores in the development and severity of inflammatory bowel diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,638,713April 1, 2022February 28, 2027SAMUELSON, DERRICK Rreporter.nih.gov
Microbiome-gut-brain dysfunction in prodromal and symptomatic Lewy body diseasesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,637,479August 1, 2023July 31, 2028RYMAN, SEPHIRAreporter.nih.gov
Coffee and metabolites modulating the gut microbiome for improved colorectal cancer survivalNIHNational Cancer Institute2022 to 2025$2,628,801June 2, 2022May 31, 2027SONG, MINGYANGreporter.nih.gov
Inflammatory cross-talk between skin and gutNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,627,786March 1, 2021February 28, 2026GALLO, RICHARD Lreporter.nih.gov
Discovery of Antibiotics from Soil Microbiomes Using MetagenomicsNIHNational Institute of General Medical Sciences2021 to 2025$2,627,250May 1, 2017August 31, 2028BRADY, SEAN Freporter.nih.gov
Role of epithelial ROS signaling in mediating psychological stress-induced mucosal dysfunction and colitis predispositionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,622,833July 31, 2022May 31, 2027ALLEN, JACOB MATTHEWreporter.nih.gov
Role of the environmental sensor, AhR on colitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,615,887September 27, 2021August 31, 2027NAGARKATTI, PRAKASH Sreporter.nih.gov
Reconstructing early life environmental exposures using tooth biomarkers and their influence on the trajectory of the oral microbiome and oral health in childhoodNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,614,819September 1, 2020May 31, 2025PETRICK, LAURENreporter.nih.gov
Systems Genetics Dissection of Non-alcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,612,818July 1, 2019March 31, 2028LUSIS, ALDONS JAKEreporter.nih.gov
the Gut Microbiome as a Disease Modifier of Heterotopic OssificationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,611,438June 1, 2022May 31, 2027PERRIEN, DANIEL Sreporter.nih.gov
The Role of Altered Luminal Dynamics in OSA-Induced AtherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,610,156July 10, 2019June 30, 2024ZARRINPAR, AMIRreporter.nih.gov
Quorum sensing, diversity and skin inflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,599,585June 12, 2020May 31, 2026HORSWILL, ALEXANDER Rreporter.nih.gov
Microbiome-mediated therapies for aging and healthspan in marmosetsNIHNational Institute on Aging2021 to 2024$2,592,378September 30, 2020May 31, 2025ROSS, CORINNA NICOLEreporter.nih.gov
Determining genomic and host-environment contributions to IBD phenotypesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,592,024September 30, 2022June 30, 2027MCGOVERN, DERMOT PATRICKreporter.nih.gov
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiotaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,589,752March 15, 2021July 6, 2026LITTMAN, DANreporter.nih.gov
Mechanisms underlying bacterial sensitivity to host-targeted drugsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,581,834June 10, 2022May 31, 2027MITCHELL, AMIRreporter.nih.gov
Investigation of FadA adhesin from Fusobacterium nucleatumNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,580,121September 10, 2020August 31, 2026HAN, YIPINGreporter.nih.gov
The Pathogenesis of Enteric FeverNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,578,362February 24, 2021January 31, 2027FANG, FERRIC Creporter.nih.gov
Micro-TeACH (Microbiome Technology and Analytic Center Hub)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,568,320March 10, 2022December 31, 2026SCHER, JOSE U.reporter.nih.gov
Interactions of dietary protein intake and intestinal resident microbiota affecting susceptibility to persistent Giardia infection and Giardia mediated enteropathyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,566,571September 21, 2020August 31, 2025BARTELT, LUTHER Areporter.nih.gov
Mechanisms of increased susceptibility to pulmonary Nontuberculous Mycobacterial disease in the elderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,558,768April 16, 2020March 31, 2026MESSAOUDI, ILHEMreporter.nih.gov
Dietary fiber and soy protein-based microbiome metabolites for IBD preventionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,557,667July 3, 2018December 31, 2026MARTENS, ERIC Creporter.nih.gov
Childhood follow-up study of obesity and neurodevelopment after perinatal exposure to adjunctive azithromycin prophylaxis for cesarean deliveryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,553,821July 20, 2020March 31, 2026SUBRAMANIAM, AKILAreporter.nih.gov
Understanding Mechanisms and Sex-Differences in Visceral PainNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,551,050September 1, 2023May 31, 2028INGRAHAM, HOLLY A.reporter.nih.gov
Interplay between host microbiome and immunomodulatory responses in the pathogenesis of Kras mutant lung cancerNIHNational Cancer Institute2021 to 2025$2,543,302February 19, 2021January 31, 2027KADARA, HUMAMreporter.nih.gov
The unleashed microbiome of cancer patients as a discovery platform for rational microbiome engineeringNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,542,500August 13, 2021July 31, 2026SCHLUTER, JONASreporter.nih.gov
The Microbiome and Biological Aging in the Add Health StudyNIHNational Institute on Aging2021 to 2024$2,535,606June 15, 2020March 31, 2026KRAUTER, KENNETH Sreporter.nih.gov
Oral Streptococcal Fitness And Virulence genesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,521,135August 3, 2021July 31, 2027XU, PINGreporter.nih.gov
Host's and microbiota's contribution to sexual dimorphism of autoimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,515,770August 16, 2017November 30, 2027CHERVONSKY, ALEXANDER Vreporter.nih.gov
Anti-tumor immunity and intestinal microbiota are modulated by mitochondrial DNANIHNational Cancer Institute2022 to 2025$2,514,943May 1, 2022April 30, 2027WALLACE, DOUGLAS Creporter.nih.gov
Methods to Test the Role of Age-related Lifestyle and Vaginal Microenvironment Changes and the Prevention, Treatment, and Progression of Genitourinary Syndrome of MenopauseNIHNational Institute on Aging2021 to 2025$2,513,445September 1, 2021May 31, 2027SHARDELL, MICHELLE DENISEreporter.nih.gov
Targeting the Mycobiome in Genetically Defined Patients with Crohns DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,513,409May 1, 2021February 28, 2026UNDERHILL, DAVID M.reporter.nih.gov
Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel DiseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,512,710July 12, 2018June 30, 2027DENSON, LEE ARMISTEADreporter.nih.gov
Childhood Pulmonary and Related Outcomes after Perinatal Exposure to Adjunctive Azithromycin Prophylaxis for Cesarean Delivery (C/SOAP Follow-Up Study)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,507,843January 20, 2020August 31, 2025SUBRAMANIAM, AKILAreporter.nih.gov
Mechanisms of Gastrointestinal COVID-19NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,503,469July 15, 2022June 30, 2027CIORBA, MATTHEW AARONreporter.nih.gov
Harnessing Antibody Responses to Prevent and Treat Urinary Tract InfectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,502,664November 10, 2021October 31, 2026KAU, ANDREW LEONreporter.nih.gov
Oral microbiome and inflammatory status in antimicrobially-treated oral cancer patientsNIHNational Cancer Institute2022 to 2025$2,501,120June 13, 2022May 31, 2027KAPILA, YVONNE Lreporter.nih.gov
Developmental flame retardant exposure, gut microbiome, and obesityNIHNational Institute of Environmental Health Sciences2021 to 2025$2,499,218January 1, 2019September 11, 2025CUI, JULIA YUEreporter.nih.gov
Dietary and Microbial Reprogramming of Intestinal Microbiota-Produced MetabolitesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,496,867September 18, 2014March 31, 2026SONNENBURG, JUSTIN Lreporter.nih.gov
Development of standardized resources for characterization of the resident ocular surface microbiome.NIHNational Eye Institute2023 to 2025$2,493,155July 1, 2023June 30, 2027ENSIGN, LAURAreporter.nih.gov
Microbial Interactions between Gardnerella, Prevotella, and Atopobium Prior to Incident Bacterial VaginosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,488,193February 1, 2020January 31, 2026MUZNY, CHRISTINA Areporter.nih.gov
Amphiregulin-Immunometabolism axis in oral immunity and inflammation during HIV infectionNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,487,093June 1, 2022May 31, 2027PANDIYAN, PUSHPAreporter.nih.gov
Mechanisms of maternal Immunoglobulin A control over the neonatal microbiota and the development of Necrotizing EnterocolitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,483,137January 15, 2020June 30, 2030HAND, TIMOTHY WESLEYreporter.nih.gov
Tolerance defenses in host-microbiota interactionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,482,877May 10, 2015March 31, 2026AYRES, JANELLE Sreporter.nih.gov
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?NIHNational Institute of Environmental Health Sciences2021 to 2024$2,479,948February 1, 2020November 30, 2025LEHMLER, HANS-JOACHIMreporter.nih.gov
The role of a bifunctional mucinase in modulating personalized gut microbiota-Vibrio cholerae interactions during infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,477,524June 1, 2023May 31, 2028ZHU, JUNreporter.nih.gov
Topical Vitamin D and Periodontal DiseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,472,056April 2, 2021March 31, 2026DIAMOND, GILLreporter.nih.gov
Human Gut Microbiome and Incident Diabetes Risk in U.S. PopulationsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,470,030January 19, 2021December 31, 2025SUN, QIreporter.nih.gov
Gut microbial fermentation products of muscle-derived lactate as mediators of exercise and metabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,469,326April 1, 2022March 31, 2027KOSTIC, ALEKSANDAR DAVIDreporter.nih.gov
Domestication and characterization of TM7-the most elusive oral phylumNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,466,563September 1, 2024August 31, 2029HE, XUESONGreporter.nih.gov
The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,466,010April 1, 2024August 31, 2026SCHWULST, STEVEN Jreporter.nih.gov
Single arm trial of menstrual cups among economically vulnerable women to reduce Bacterial vaginosis and STIs through reduced harmful sexual and menstrual practicesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,463,754August 1, 2025July 31, 2027MEHTA, SUPRIYA DINESHreporter.nih.gov
High-resolution, virome-wide infection analysis in type 1 diabetes birth cohortsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$2,459,418June 1, 2024May 31, 2027ALTIN, JOHNreporter.nih.gov
The Microbiome-Gut-Brain Axis and Personalized Mediterranean Diet Interventions for Alzheimer's Dementia PreventionNIHNational Institute on Aging2024$2,451,933May 15, 2024April 30, 2027WANG, DONGreporter.nih.gov
Control of GVHD by Probiotics with individual Commensal BacteriaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,448,717May 5, 2022April 30, 2027YU, XUE-ZHONGreporter.nih.gov
Host integration of commensal and pathogenic bacterial-derived signalsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,446,303June 4, 2018May 31, 2027ALENGHAT, THERESAreporter.nih.gov
Aging, macrophage mediators, and burn trauma: SupplementNIHNational Institute on Aging2021 to 2024$2,445,102February 1, 2001May 31, 2026KOVACS, ELIZABETH J.reporter.nih.gov
Preventing norovirus and Clostridium difficile gastroenteritis by engineered probiotic yeast Saccharomyces boulardii secreting multi-specific single-domain antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,441,424January 22, 2020December 31, 2025FENG, HANPINGreporter.nih.gov
Role of the gut microbiome in the bone loss induced by hyperparathyroidism in mice and humansNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,440,273February 1, 2021January 31, 2026PACIFICI, ROBERTOreporter.nih.gov
Early life regulation of microbiota specific thymic T cell developmentNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,439,253November 7, 2022October 31, 2027BETTINI, MATTHEWreporter.nih.gov
Trauma, the gut, and the brain: the gut microbiota-microglia axis in traumatic brain injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,439,002August 1, 2022July 31, 2027SCHWULST, STEVEN Jreporter.nih.gov
A Novel Microbiome-Based Immune-Modulator that Potentiates Cancer Checkpoint TherapyNIHNational Cancer Institute2021 to 2024$2,436,171April 1, 2021June 30, 2026FANGER, GARYreporter.nih.gov
A Novel Immunological-Directed Biotherapy for Treating Rheumatoid ArthritisNIHNational Institute on Aging2023 to 2025$2,434,680September 4, 2023June 30, 2027FANGER, GARYreporter.nih.gov
The Role in OAT1 in UremiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,431,655January 15, 2017July 31, 2026NIGAM, SANJAY Kreporter.nih.gov
Dissecting the role of sialic acid and sialidase in the pathophysiology of Porphyromonas gingivalisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,431,360February 15, 2021January 31, 2027LI, CHUNHAO CHRISreporter.nih.gov
Gut microbial metabolites and risk of coronary heart disease: a prospective, multiethnic, metabolomic studyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,429,547July 15, 2020June 30, 2025YU, DANXIAreporter.nih.gov
Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,421,990September 1, 2021July 31, 2026CERVANTES BARRAGAN, LUISAreporter.nih.gov
A scalable platform for highly-multiplexed analysis of antibody reactivity from <1uL of bloodNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,420,790April 10, 2020March 31, 2025ALTIN, JOHNreporter.nih.gov
Deciphering the crosstalk between bacteria and their mammalian hostsNIHNational Center for Complementary & Integrative Health2022 to 2025$2,416,405September 1, 2025August 31, 2027WHITELEY, AARON THOMASreporter.nih.gov
Mathematical ecology models of host-microbiota interaction in auto microbiota transplants (auto-FMT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,414,163February 1, 2019January 31, 2024XAVIER, JOAOreporter.nih.gov
Virome and Immune Responses associated with IA and Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$2,412,388March 5, 2024January 31, 2027LLOYD, RICHARD Ereporter.nih.gov
Molecular basis of heme scavenging by Gram-positive bacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,409,544January 19, 2021December 31, 2026CLUBB, ROBERT THOMPSONreporter.nih.gov
Tuft cell heterogeneity in function, lineage, and structure in ileal inflammatory diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,405,842February 15, 2016January 31, 2026LAU, KEN Sreporter.nih.gov
MicroRNA Predictors of HIV Risk in Reproductive Age WomenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,402,650May 13, 2019March 31, 2025FICHOROVA, RAINA N.reporter.nih.gov
Web-Based Resource for Genomic Enzymology ToolsNIHNational Institute of General Medical Sciences2022 to 2025$2,402,510January 10, 2022December 31, 2026GERLT, JOHN Areporter.nih.gov
Leveraging early-life microbes to prevent type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,398,489April 1, 2023February 29, 2028SILVERMAN, MICHAEL Areporter.nih.gov
The Gut Microbiome, Lifestyle, and Colorectal NeoplasiaNIHNational Cancer Institute2022 to 2025$2,397,399May 1, 2022April 30, 2027SONG, MINGYANGreporter.nih.gov
Microbiome-driven immune changes and growth stunting in HIV-exposed uninfected childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,396,349May 11, 2023January 31, 2028BEBELL, LISA Mreporter.nih.gov
Maternal diet and programming of offspring gut-brain axisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,395,660June 30, 2022April 30, 2027TAMASHIRO, KELLIE L. K.reporter.nih.gov
Functional Dissection of Regulatory Myeloid Cells in Microbe-Immune Crosstalk in SkinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,391,981April 7, 2022January 31, 2027SCHARSCHMIDT, TIFFANY CRAWFORDreporter.nih.gov
Annotating carbohydrate structures to develop markers for consumption of foodNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,391,222April 1, 2020December 31, 2025LEBRILLA, CARLITO Breporter.nih.gov
How sex, host microenvironment, and immune responses shape acquisition of genital bacteria that increase HIV riskNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,387,782December 1, 2021November 30, 2026LIU, CINDYreporter.nih.gov
Immunological and Microbial Mechanisms in Food AllergyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,387,215November 21, 2016January 31, 2028CHATILA, TALAL AMINEreporter.nih.gov
Roles of sialidase in G. vaginalis-host interactions during bacterial vaginosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,385,117December 1, 2014November 30, 2025LEWIS, AMANDA L.reporter.nih.gov
Sulfide metabolism and signalingNIHNational Institute of General Medical Sciences2021 to 2025$2,381,639January 1, 2019December 31, 2028BANERJEE, RUMA Vreporter.nih.gov
Commensal Candida albicans primed Th17 immunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,379,060July 1, 2023June 30, 2028WAY, SING SINGreporter.nih.gov
Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,378,553January 1, 2021December 31, 2026AHERN, PHILIP PATRICKreporter.nih.gov
Fungal dysbiosis regulation of post-influenza bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,376,545July 16, 2021June 30, 2025CHEN, PETERreporter.nih.gov
Pore Formation by Cholesterol Dependent CytolysinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,375,765April 1, 1997March 31, 2027TWETEN, RODNEY K.reporter.nih.gov
Mechanisms of SARS-CoV-2 pathogenesis during HIV/SIV infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,375,036August 28, 2023July 31, 2028O'CONNOR, MEGAN Areporter.nih.gov
Acute kidney injury and microbiomeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,372,693July 15, 2020April 30, 2026RABB, HAMIDreporter.nih.gov
The Role of the Intestinal Mycobiome in Alcoholic Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,368,040June 1, 2017March 31, 2027SCHNABL, BERND G.reporter.nih.gov
MECHANISMS OF VISCERAL PAIN DRIVEN BY SMALL INTESTINAL MICROBIOTANIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,366,065September 19, 2023July 31, 2028KASHYAP, PURNA Creporter.nih.gov
Integration of mononuclear phagocytes into the human gastrointestinal GOFlowChip for investigation of luminal antigen samplingNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$2,363,783September 30, 2019June 30, 2025WALK, SETH Treporter.nih.gov
Impact of microbiota on AIDS-Kaposi’s sarcoma development and therapyNIHNational Cancer Institute2023 to 2025$2,362,235September 8, 2023August 31, 2028GAO, SHOU-JIANGreporter.nih.gov
Immunologic and Imaging studies with TNF Therapy in Prodromal SynucleinopathiesNIHNational Institute on Aging2025$2,361,361September 1, 2025August 31, 2030CEDARBAUM, JESSEreporter.nih.gov
Dissecting the modulatory functions of interleukin-17 in Alzheimer's DiseaseNIHNational Institute on Aging2023$2,359,602December 15, 2022November 30, 2025HUH, JUN R.reporter.nih.gov
Effect of Dietary Carbohydrate on Diabetes Control and Beta Cell Function in Children with Newly Diagnosed Diabetes.”NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,359,048May 1, 2023April 30, 2029LENNERZ, BELINDA Sreporter.nih.gov
Bayesian multivariate 3D spatial modeling for microbiome image analysisNIHNational Institute of General Medical Sciences2021 to 2024$2,357,728May 4, 2021February 28, 2026STARR, JACQUELINE Rreporter.nih.gov
Investigating Immune-Microbiome interactions during treatment of Clostridioides difficile with fecal microbiome transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,357,199February 5, 2021January 31, 2027ABT, MICHAEL C.reporter.nih.gov
Gut pathogen virulence and its therapeutic modulation during surgical injuryNIHNational Institute of General Medical Sciences2021 to 2025$2,357,080February 1, 2001March 31, 2027ALVERDY, JOHN Creporter.nih.gov
Microbiome Function in Atopic DermatitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,356,653May 1, 2020April 30, 2027GALLO, RICHARD Lreporter.nih.gov
Targeting bacterial proteases involved in PAR signaling to treat inflammatory bowel diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,355,154September 21, 2021July 31, 2026BOGYO, MATTHEWreporter.nih.gov
Treponema - Host Cell and Tissue InteractionsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,355,086July 1, 2015January 31, 2027FENNO, J CHRISTOPHERreporter.nih.gov
Kidney Stone Disease In ADPKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,353,533September 22, 2021June 30, 2027CHONCHOL, MICHEL BENJAMINreporter.nih.gov
Nutritional immunity and microbial competition during Clostridioides difficile infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,352,660June 13, 2022May 31, 2027SKAAR, ERIC Preporter.nih.gov
Caries resistance mechanisms in high-risk Indigenous childrenNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,350,281April 4, 2023March 31, 2028BIDLACK, FELICITAS Breporter.nih.gov
Quorum Sensing Regulation of EHEC Virulence GenesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,346,135January 1, 2023December 31, 2027SPERANDIO, VANESSAreporter.nih.gov
Dark GPCR signaling underlying the Microbiome-Gut-Brain Axis for Alzheimer's Disease and Related DementiaNIHNational Institute of Neurological Disorders and Stroke2023$2,344,291August 18, 2023July 31, 2026CHENG, FEIXIONGreporter.nih.gov
Human microbiome metabolites in health and diseaseNIHNational Institute of General Medical Sciences2021 to 2025$2,343,863July 1, 2018June 30, 2028DEVLIN, ABIGAIL SLOANreporter.nih.gov
Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic DermatitisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,339,515March 22, 2023February 29, 2028GEHA, RAIF SALIMreporter.nih.gov
Connecting the Spatiotemporal Organization of Gut Bacterial Communities to the Emergence and Spread of Antibiotic ResistanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,339,120May 5, 2021October 31, 2026WILES, TRAVIS Jreporter.nih.gov
Diet-derived oxysterols shape intestinal B cell fate by controlling intracellular cholesterol metabolismNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,336,135June 25, 2021May 31, 2027REBOLDI, ANDREAreporter.nih.gov
The natural history of C. trachomatis urethral infections in men who have sex with womenNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,335,516July 5, 2023June 30, 2028NELSON, DAVID EMMETreporter.nih.gov
Prenatal and Postnatal Mitochondrial Dysfunction in the Pathogenesis of Necrotizing EnterocolitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,334,824September 1, 2025August 31, 2029HACKAM, DAVID Jreporter.nih.gov
Role of colonic enteroendocrine cells in metabolic controlNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,334,511August 1, 2022May 31, 2027BURSTEIN, EZRAreporter.nih.gov
Development of Engineered Native Bacteria as a Tool for Functional Manipulation of the Gut MicrobiomeNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,332,857June 20, 2023May 31, 2028ZARRINPAR, AMIRreporter.nih.gov
Impact of symbiotic protists on intestinal T cell homeostasis and inflammation.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,328,152March 1, 2021February 28, 2026HOWITT, MICHAEL Rreporter.nih.gov
Aldehydes in Alcohol-Induced Organ InjuryNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,325,195September 30, 2010February 29, 2028ZHOU, ZHANXIANGreporter.nih.gov
Defining Sex-Specific Systemic and Gut Inflammatory Profiles in People Living with HIVNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,321,996January 3, 2023December 31, 2027SMITH, STACEY ABIGAILreporter.nih.gov
PediatRic sEpsiS induCed MODS: Relationship of Immune-phenotypes and antiBiotic Exposures (PRESCRIBE) studyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,321,738June 19, 2023May 31, 2028DOWNES, KEVIN JAMESreporter.nih.gov
Microbiota, Probiotic and Dietary Metabolite Control of Enteric Pathogen VirulenceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,318,817November 10, 2022October 31, 2027HANG, HOWARD Creporter.nih.gov
DYSBIOTIC MICROBIOME IN PANCREATITIS, DIABETES, AND PANCREATIC CANCERNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,315,838September 28, 2015June 30, 2025FISHER, WILLIAM Ereporter.nih.gov
Investigations of Lyme spirochete transmission as a complex network of microbial and ecological interactionsNIHNational Institute of General Medical Sciences2022 to 2025$2,315,379September 16, 2022July 31, 2027COURET, JANNELLEreporter.nih.gov
Biomarker Identification, Viral Susceptibility and Management in S. aureus Colonized AD PatientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,310,254April 6, 2020March 31, 2027BECK, LISA ANNreporter.nih.gov
Microbiota outgrowth by SalmonellaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,306,740May 1, 2011June 30, 2026BAUMLER, ANDREAS Jreporter.nih.gov
Gut Microbiome and Cancer Immunotherapy Outcomes in Advanced Renal Cell CarcinomaNIHNational Cancer Institute2022 to 2025$2,305,974March 1, 2022February 28, 2027FEDIRKO, VERONIKAreporter.nih.gov
How E. coli Acid Response Mechanisms Breach Colonization Resistance in the VaginaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,302,945July 1, 2022June 30, 2027HADJIFRANGISKOU, MARIAreporter.nih.gov
Fecal microbiota transplant for Alcohol-Associated CirrhosisNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,300,878September 12, 2022August 31, 2027BAJAJ, JASMOHAN Sreporter.nih.gov
The impact of upper gastrointestinal dysmotility on aspiration-associated aerodigestive disorders in childrenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,300,603July 1, 2015May 31, 2027ROSEN, RACHEL Lreporter.nih.gov
Metabolism of cancer chemotherapeutics by the human gut microbiomeNIHNational Cancer Institute2023 to 2025$2,300,078September 1, 2023August 31, 2028TURNBAUGH, PETER JAMESreporter.nih.gov
Neonatal gut-on-a-chip platform for high content drug testing and precision medicineNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,297,962April 1, 2022August 31, 2025GOOD, MISTY Lreporter.nih.gov
Balanced Energy Protein Supplement in Early Lactation on Infant Growth in Southern NepalNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,290,371September 19, 2022July 31, 2027ERCHICK, DANIEL JOSEPHreporter.nih.gov
Immune Interactions with the Mucus-Associated MicrobiotaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,287,659July 12, 2021June 30, 2027MAYNARD, CRAIG Lreporter.nih.gov
Characterizing and predicting colitis in immune checkpoint blockade-treated cancer patientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,286,893June 1, 2020May 31, 2026GNJATIC, SACHAreporter.nih.gov
Fitness Effects of Beneficial MutationsNIHNational Institute of General Medical Sciences2021 to 2025$2,286,190May 1, 2019April 30, 2029SHERLOCK, GAVIN Jreporter.nih.gov
LIMA: Lipid anti-Inflammatory Mediators in Asthma to reduce airway hyperresponsiveness in obese asthmaticsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,285,261May 1, 2022April 30, 2027HOLGUIN, FERNANDOreporter.nih.gov
Goblet Cells in Intestinal HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,283,637September 17, 2012June 30, 2027NEWBERRY, RODNEY Dreporter.nih.gov
Microbiota-based probiotics to treat inborn errors in metabolismNIHNational Center for Complementary & Integrative Health2022 to 2025$2,280,969February 16, 2022January 31, 2027DODD, DYLANreporter.nih.gov
Activity Probes to Guide Precision Microbiome TherapyNIHNational Center for Complementary & Integrative Health2024 to 2025$2,279,811September 1, 2024May 31, 2029LONGMAN, RANDY Sreporter.nih.gov
Role of the oral microbiome in driving local and systemic inflammation in HIVNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,277,570August 1, 2023July 31, 2028FULCHER, JENNIFERreporter.nih.gov
Contribution of immune modulation, metabolism, and microbiota to Group B Streptococcal urinary tract infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,277,552September 21, 2021June 30, 2027PATRAS, KATYreporter.nih.gov
A Novel Immunological-Directed Live Biotherapy Product for Treating Ulcerative ColitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$2,277,236July 5, 2022July 31, 2025FANGER, GARYreporter.nih.gov
Understanding redox-regulated mechanisms of environmental adaptation in gastrointestinal symbiontsNIHNational Institute of General Medical Sciences2021 to 2025$2,272,455August 1, 2020May 31, 2030HATZIOS, STAVROULAreporter.nih.gov
Integrative and longitudinal multi-omic risk assessment in inflammatory bowel disease progressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,272,364September 30, 2022June 30, 2027KUGATHASAN, SUBRAreporter.nih.gov
Metabolic Basis of Bacterial Community Function in the Cystic Fibrosis AirwayNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,268,565June 2, 2021May 31, 2026O'TOOLE, GEORGE A.reporter.nih.gov
Reducing innate inflammation in new onset T1D with Lactobacillus plantarumNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,267,995August 21, 2020May 31, 2026HESSNER, MARTIN Jreporter.nih.gov
Pathogenesis of Early Onset Colorectal Cancer: Microbiome Contributions and MechanismsNIHNational Cancer Institute2021 to 2025$2,266,043September 23, 2021August 31, 2026SEARS, CYNTHIAreporter.nih.gov
Defining non-genetic mechanisms that prevent death in a Hirschsprung disease mouse modelNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,261,547August 27, 2021May 31, 2026HEUCKEROTH, ROBERT Oreporter.nih.gov
Exacerbation of Colitis by EnterobacteriaceaeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,260,715January 15, 2015March 31, 2026BAUMLER, ANDREAS Jreporter.nih.gov
Repurposing of Metormin for Older Patients with HFpEFNIHNational Institute on Aging2022 to 2024$2,257,874August 1, 2022July 31, 2026KITZMAN, DALANE Wreporter.nih.gov
Role of Type 2 Immunity in Innate Protection from C. difficileNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,257,824February 2, 2016January 31, 2027PETRI, WILLIAM Areporter.nih.gov
Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)NIHNational Institute of Mental Health2021 to 2023$2,257,672September 15, 2021September 2, 2023CARRICO, ADAM WAYNEreporter.nih.gov
Host-associated biofilm formation and dispersal mechanismsNIHNational Institute of General Medical Sciences2021 to 2025$2,257,572May 1, 2019April 30, 2029VISICK, KAREN Lreporter.nih.gov
Whole Body Deep Tissue Characterization of the Human ViromeNIHNational Center for Complementary & Integrative Health2024 to 2025$2,255,898September 13, 2024August 31, 2029HENRICH, TIMOTHY JENSENreporter.nih.gov
Microbial regulation of mammalian circadian rhythms and the sexual dimorphism: from metabolism to immunityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,254,500September 19, 2022August 31, 2027KUANG, ZHENGreporter.nih.gov
Tryptophan derivatives in EHEC pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,253,769August 8, 2022January 31, 2027SPERANDIO, VANESSAreporter.nih.gov
Collaborative Microbial Metabolite CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,248,758September 1, 2022June 30, 2027DORRESTEIN, PIETER Creporter.nih.gov
The Microbiome and Mucosal Immunity in Cervical Cancer DisparitiesNIHNational Cancer Institute2022 to 2025$2,247,793April 25, 2022March 31, 2027BURGENER, ADAMreporter.nih.gov
ß-hydroxybutyrate inhibition of pathology in Alzheimer's diseaseNIHNational Institute on Aging2023 to 2025$2,247,073August 1, 2023July 31, 2028ULLAND, TYLER KENTreporter.nih.gov
Lipid-dependent host-microbe interactionsNIHNational Institute of General Medical Sciences2021 to 2025$2,245,604August 1, 2020May 31, 2030JOHNSON, ELIZABETH Lreporter.nih.gov
Culture-free pathogen tracking in hospitalized patientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,245,086April 3, 2020March 31, 2025BHATT, AMI SIDDHARTHreporter.nih.gov
Bacterial adaptions in host-microbe interactions.NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,240,628March 11, 2022February 28, 2027CHU, HIUTUNGreporter.nih.gov
Machine Learning and Control Principles for Computational BiologyNIHNational Institute of General Medical Sciences2021 to 2025$2,237,500September 1, 2021August 31, 2026GIBSON, TRAVIS ELIreporter.nih.gov
Reciprocal Modulation of the Microbiome and Cellular Senescence in Metabolic DysfunctionNIHNational Institute on Aging2021 to 2024$2,237,377September 10, 2020May 31, 2026ZHOU, YANJIAOreporter.nih.gov
Positive Immune-regulators During Chronic Viral InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,236,668February 1, 2015June 30, 2025ZUNIGA, ELINA Ireporter.nih.gov
Determinants of the periocular microbiomeNIHNational Eye Institute2023 to 2025$2,236,328July 1, 2023June 30, 2026VAN GELDER, RUSSELL N.reporter.nih.gov
Microbial reactivation of sex steroids and visceral painNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,236,187August 1, 2022May 31, 2027RAO, MEENAKSHIreporter.nih.gov
Oral Epithelial Cells, Candida and PMN ActivationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,233,413September 29, 2000July 31, 2026DONGARI-BAGTZOGLOU, ANNA Ireporter.nih.gov
A comprehensive investigation of Pseudomonas quorum sensing regulatory relationships and the consequences on quorum sensing inhibitors in complex communitiesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,232,732July 1, 2023June 30, 2028RAHME, LAURENCE Greporter.nih.gov
A multiscale approach to develop and apply fluoride efflux inhibitors to reverse oral dysbiosis and eliminate early childhood cariesNIHNational Institute of Dental & Craniofacial Research2024 to 2025$2,229,042September 12, 2024June 30, 2029STOCKBRIDGE, RANDY B.reporter.nih.gov
CANCAN - COLDSPRINGNIHNational Cancer Institute2022 to 2025$2,225,345June 22, 2022May 31, 2026JANOWITZ, TOBIASreporter.nih.gov
Maintenance of mucosal homeostasis by commensal Th17 cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,225,217August 6, 2021May 31, 2026IVANOV, IVAYLO IVANOVreporter.nih.gov
PROSPECT-Global Consortium and Risk Factor DiscoveryNIHNational Cancer Institute2024 to 2025$2,222,328May 1, 2024April 30, 2026CAO, YINreporter.nih.gov
Dynamic changes in virome-host interactions during pregnancy and postpartumNIHNational Center for Complementary & Integrative Health2024 to 2025$2,222,038September 17, 2024August 31, 2029WYLIE, KRISTINE M.reporter.nih.gov
Colorectal carcinogenesis and Fusobacterium nucleatum: oncomicrobe, oncometabolites, and oncoimmunologyNIHNational Cancer Institute2021 to 2025$2,221,814March 18, 2011July 31, 2027GARRETT, WENDY S.reporter.nih.gov
Gut-microbial metabolism of aromatic amino acids and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,221,265December 15, 2021November 30, 2026NEMET, INAreporter.nih.gov
Toward Personalized Therapeutics: Directed Remodeling of the Gut Microbiome to Treat AtherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,216,742April 22, 2020September 30, 2024GHADIRI, M. REZAreporter.nih.gov
Relating impacts of antibiotics on the gut metabolome and microbiome to host physiology and weightNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,214,927August 1, 2020May 31, 2026BELENKY, PETERreporter.nih.gov
Prenatal neuroinflammation: maternal microbiome contributions and behavioral consequencesNIHNational Institute of Mental Health2022 to 2025$2,209,338May 1, 2022February 28, 2027GUR, TAMARreporter.nih.gov
Systemic immunoregulatory consequences of bacterial translocation during health and diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,209,196September 21, 2021June 30, 2026MEISEL, MARLIESreporter.nih.gov
Dissecting the Source and Mechanisms of IL-17-Mediated Modulation of Pancreatic TumorigenesisNIHNational Cancer Institute2021 to 2025$2,204,373September 18, 2020August 31, 2027MCALLISTER, FLORENCIAreporter.nih.gov
Strengthening gut barrier integrity with beneficial microbes to increase lifespan and healthspanNIHNational Institute on Aging2022 to 2025$2,197,864September 15, 2021May 31, 2027CROTT, JIMMY Wreporter.nih.gov
In vivo mechanisms mediating sickle cell vaso-occlusion and organ damageNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,197,616September 30, 2001August 31, 2025KELLY, LIBUSHAreporter.nih.gov
Microbial regulation of the keratinocyte AHRNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,197,247April 1, 2022March 31, 2027GRICE, ELIZABETH ANNEreporter.nih.gov
Molecular and cellular mechanisms in food anaphylaxisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,192,068June 1, 2020May 31, 2025GEHA, RAIF SALIMreporter.nih.gov
Blocking CMV transmission through the human milk metabolome and microbiomeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,191,788April 1, 2021March 31, 2026MARQUEZ-LAGO, TATIANA T.reporter.nih.gov
Alcohol and Burn Trauma: Multi-organ Inflammatory ResponsesNIHNational Institute of General Medical Sciences2021 to 2025$2,191,572September 20, 2019June 30, 2029KOVACS, ELIZABETH J.reporter.nih.gov
Regulation of Gut Innate Lymphoid Cells by AhrNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,190,711July 15, 2017June 30, 2028ZHOU, LIANGreporter.nih.gov
Environmental factors in pathobiology of dementia: the role of PCB exposure, microbiome, and tissue barrier dysfunctionNIHNational Institute of Environmental Health Sciences2023 to 2025$2,186,707January 1, 2023November 30, 2026LEHMLER, HANS-JOACHIMreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Leidos Biomedical Research, Inc.Frederick, MD1$2.96 billion0$0
Washington UniversitySaint Louis, MO92$155.9 million0$0
University of California, San DiegoLa Jolla, CA76$133.2 million0$0
University of Wisconsin-MadisonMadison, WI61$101.3 million0$0
Massachusetts General HospitalBoston, MA54$77.7 million0$0
Brigham and Women's HospitalBoston, MA46$77.1 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY48$73.6 million0$0
University of Colorado DenverAurora, CO78$73.3 million0$0
University of Michigan at Ann ArborAnn Arbor, MI80$72.7 million0$0
University of PennsylvaniaPhiladelphia, PA72$69.5 million0$0
University of California, San FranciscoSan Francisco, CA57$69.1 million0$0
University of ChicagoChicago, IL45$66.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC52$66 million0$0
Duke UniversityDurham, NC51$62.6 million0$0
Emory UniversityAtlanta, GA57$61.1 million0$0
Vanderbilt University Medical CenterNashville, TN38$61.1 million0$0
Columbia University Health SciencesNew York, NY40$60.2 million0$0
Baylor College of MedicineHouston, TX57$59.9 million0$0
New York University School of MedicineNew York, NY37$55 million0$0
Johns Hopkins UniversityBaltimore, MD55$54.9 million0$0
Weill Medical Coll of Cornell UnivNew York, NY53$50.9 million0$0
University of California Los AngelesLos Angeles, CA48$49.7 million0$0
University of WashingtonSeattle, WA46$49.7 million0$0
Dartmouth CollegeHanover, NH12$48.4 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA48$47.6 million0$0
Case Western Reserve UniversityCleveland, OH22$47.4 million0$0
Yale UniversityNew Haven, CT35$47 million0$0
University of FloridaGainesville, FL52$46.5 million0$0
University of Alabama at BirminghamBirmingham, AL47$45.4 million0$0
Northwestern University at ChicagoChicago, IL13$45.2 million0$0
Albert Einstein College of MedicineBronx, NY18$44.9 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA17$42.6 million0$0
Stanford UniversityStanford, CA49$42.5 million0$0
Boston Children's HospitalBoston, MA22$42 million0$0
University of California at DavisDavis, CA40$39.8 million0$0
University of LouisvilleLouisville, KY26$39.8 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH25$32.5 million0$0
Rho Federal Systems Division, Inc.Durham, NC1$32.1 million0$0
University of VirginiaCharlottesville, VA23$30.8 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA26$30.6 million0$0
University of South Carolina at ColumbiaColumbia, SC10$30.1 million0$0
Ada Forsyth Institute, Inc.Somerville, MA18$29.8 million0$0
University of Illinois at ChicagoChicago, IL33$29.1 million0$0
Scripps Research Institute, theLa Jolla, CA8$28.7 million0$0
University of Maryland BaltimoreBaltimore, MD26$27.8 million0$0
University of Miami School of MedicineCoral Gables, FL21$27.7 million0$0
National Jewish HealthDenver, CO1$27.2 million0$0
Ut Southwestern Medical CenterDallas, TX33$26.9 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR3$26.8 million0$0
Tulane University of LouisianaNew Orleans, LA11$26 million0$0
University of ArizonaTucson, AZ15$26 million0$0
University of UtahSalt Lake City, UT20$25.7 million0$0
University of TX MD Anderson Can CTRHouston, TX25$25.4 million0$0
University of MinnesotaMinneapolis, MN43$25.4 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY5$24.9 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH21$24.8 million0$0
Boston University Medical CampusBoston, MA8$24.7 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA19$24.2 million0$0
University of RochesterRochester, NY16$23.3 million0$0
Rise Therapeutics, LLCRockville, MD12$23.2 million0$0
Ohio State UniversityColumbus, OH28$22.4 million0$0
Oregon Health & Science UniversityPortland, OR19$22.1 million0$0
Fred Hutchinson Cancer CenterSeattle, WA14$21.8 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA23$21.3 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX23$21.2 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY11$20.9 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL18$20.8 million0$0
Mayo Clinic RochesterRochester, MN14$19.4 million0$0
Cornell UniversityIthaca, NY18$18.8 million0$0
University of Southern CaliforniaLos Angeles, CA9$18 million0$0
University of KentuckyLexington, KY15$17.9 million0$0
Indiana University IndianapolisIndianapolis, IN17$16.9 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ21$16.8 million0$0
Princeton UniversityPrinceton, NJ11$16.7 million0$0
Michigan State UniversityEast Lansing, MI11$16.3 million0$0
Rush University Medical CenterChicago, IL15$16.2 million0$0
SUNY at BuffaloAmherst, NY25$15.9 million0$0
Hektoen Institute for Medical ResearchChicago, IL1$15.7 million0$0
Harvard Medical SchoolBoston, MA21$15.4 million0$0
University of Missouri-ColumbiaColumbia, MO10$15.3 million0$0
Virginia Commonwealth UniversityRichmond, VA18$14.8 million0$0
University of Connecticut SCH of Med/dntFarmington, CT14$14.7 million0$0
University of California-IrvineIrvine, CA13$14.5 million0$0
Seattle Children's HospitalSeattle, WA11$14.5 million0$0
University of IowaIowa City, IA18$14.3 million0$0
University of HawaiiHonolulu, HI7$14.1 million0$0
Augusta UniversityAugusta, GA4$13.8 million0$0
New York UniversityNew York, NY9$12.8 million0$0
Rockefeller UniversityNew York, NY9$12.7 million0$0
Brown UniversityProvidence, RI13$12.7 million0$0
Medical College of WisconsinMilwaukee, WI14$12.6 million0$0
University of Georgia Research Foundation IncAthens, GA8$12.4 million0$0
University of Tennessee Health Sci CTRMemphis, TN11$12.2 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA16$11.7 million0$0
University of Nebraska-LincolnLincoln, NE6$11.5 million0$0
Beckman Research Institute/city of HopeDuarte, CA7$11.4 million0$0
University of California-BerkeleyBerkeley, CA13$11.2 million0$0
Georgia State UniversityAtlanta, GA6$11.1 million0$0
Montana State UniversityBozeman, MT7$10.6 million0$0
Massachusetts Institute of TechnologyCambridge, MA10$10.4 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,604$1,315,802,8110$0
20241,707$1,365,549,8440$0
20231,656$1,646,368,9470$0
20221,621$1,405,466,4460$0
20211,532$1,371,367,7610$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 30 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 9 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)PA-24-181NIHMay 8, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIHDecember 3, 2026Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 798 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 798 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 798 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 798 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 798 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 798 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 798 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 798 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 798 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 798 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 798 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 798 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.