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Data / Research funding / Malaria Vaccine

Malaria Vaccine: 144 NIH awards ($216M) to 62 organizations

144 NIH awards ($216M) in the NIH spending category Malaria Vaccine, to 62 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

144 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
University of Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,173,751December 11, 2019November 30, 2026WALD, ANNAreporter.nih.gov
Kaiser Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,173,633December 11, 2019November 30, 2026JACKSON, LISA Areporter.nih.gov
Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,330,175February 4, 2021January 31, 2026KAPPE, STEFAN HIreporter.nih.gov
Expanding the breadth, magnitude, and durability of PfSPZ vaccines by creating multi-strain vaccines, designer hybrid and genetically altered parasite vaccines and use of a unique adjuvant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,933,702April 8, 2021March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Computational models of naturally acquired immunity to falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,666,873April 1, 2020March 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,835,728December 1, 2020November 30, 2026ADAMS, JOHN Hreporter.nih.gov
Development of Non-Human Primate Models to Assess Immunological Mechanisms and Antigenic Targets of Protective Sporozoite (SPZ) Vaccines and Establish Superior Efficacy of Next Generation SPZ vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,717,265April 1, 2021March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,114,200February 10, 2022January 31, 2027WILDER, BRANDON KEITHreporter.nih.gov
Development of an oral liver-targeted prime-and-trap malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,104,491December 1, 2020November 30, 2026MURPHY, SEAN Creporter.nih.gov
Defining functional humoral correlates of immunity to guide vaccine designNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,023,233November 24, 2020October 31, 2025BATISTA, FACUNDO DAMIANreporter.nih.gov
A systems immunology approach to evaluate malaria vaccine performance in endemic regions of KenyaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,921,000February 1, 2022January 31, 2027MOORMANN, ANN Mreporter.nih.gov
Inducing durable, protective immune memory against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,488,192January 16, 2019December 31, 2023KAPPE, STEFAN HIreporter.nih.gov
Structure and function of the Plasmodium myosin XIV-actin glideosome.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,384,780May 11, 2017June 30, 2027TRYBUS, KATHLEEN Mreporter.nih.gov
Once Bitten: Acquisition of Malaria Adaptive Immunity (OBAMA - Immunity)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,285,014July 1, 2025June 30, 2028PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Drivers of strain-specific and strain-transcendent antimalarial immunity in childhoodNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,209,021June 17, 2020May 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Systems biological assessment of vaccination-induced protective immunity in African childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,984February 1, 2022January 31, 2027PULENDRAN, BALIreporter.nih.gov
A Unique Automated Bioreactor for Rearing Aseptic Mosquitoes from Larvae to Adults to Support Manufacture of Sanaria PfSPZ ProductsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000July 18, 2018March 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,001April 21, 2020March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Progressing PfSPZ vaccines for malaria to licensure and commercializationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,994,338April 14, 2023March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
A glycolipid adjuvant to promote dose sparing, accelerate immunization schedules and extend durability of high-level protection with an attenuated, live sporozoite malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,935,817July 1, 2016June 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
A universal malaria T cell vaccine based on HLA-E presentationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,934,908May 20, 2022April 30, 2027WILDER, BRANDON KEITHreporter.nih.gov
Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,925,300May 17, 2018June 30, 2025KHUONG, NHIreporter.nih.gov
Automating mosquito microdissection for a malaria PfSPZ vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,924,306June 20, 2017April 30, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Defining targets of protective immunity to vivax malaria using human monoclonal antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,825,320March 24, 2020February 28, 2026KING, CHRISTOPHER Lreporter.nih.gov
Accelerating Malaria Vaccines with a Custom Preclinical Humanized Mouse Model PlatformNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,803,324March 1, 2022February 28, 2027BATISTA, FACUNDO DAMIANreporter.nih.gov
Developing a multi-component vaccine harnessing potent antibody and cellular responses against the blood-stage of Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,802,178May 1, 2022April 30, 2027SRINIVASAN, PRAKASHreporter.nih.gov
Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine CandidatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,788,646August 1, 2025July 31, 2027BEI, AMY KRISTINEreporter.nih.gov
Collective Responses to Malaria VaccinationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,779,001February 9, 2022January 31, 2027STUART, KENNETH Dreporter.nih.gov
Harnessing the Malarial Immunity Omics Landscape in Vaccinated and Unvaccinated Children for Improved Therapeutic StrategiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,743,704July 1, 2025June 30, 2029PERKINS, DOUGLAS JAYreporter.nih.gov
Defining conserved epitopes on polymorphic malaria antigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,726,813February 19, 2021January 31, 2027BUNNIK, EVELIEN MARGARETHAreporter.nih.gov
Baseline host and environmental factors that impact pre-erythrocytic malaria vaccine (hypo)responsiveness in endemic regionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,600,040March 8, 2022February 28, 2027YAZDANBAKHSH, MARIAreporter.nih.gov
A GLYCOLIPID ADJUVANT 7DW8-5 FOR MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,501,040September 30, 2023September 29, 2028TSUJI, MORIYAreporter.nih.gov
Development of a pre-erythrocytic P. vivax vaccine to prevent clinical relapseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,467,626January 1, 2019December 31, 2023SATHER, D. NOAHreporter.nih.gov
Immunity to Liver-stage malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,414,340January 12, 2022January 14, 2025HARTY, JOHN Treporter.nih.gov
Liver resident memory for malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,368,344November 23, 2018October 31, 2024MURPHY, SEAN Creporter.nih.gov
Genome-wide sieve analysis and immunological validation to identify targets of protective efficacy in field trials of a whole-organism malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,110,841January 15, 2019December 31, 2024CARNEIRO DA SILVA, JOANAreporter.nih.gov
The role of natural killer cells and antibodies in protection from malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,108,688March 25, 2020February 28, 2026HART, GEOFFREY Treporter.nih.gov
Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,067,031April 1, 2003June 30, 2029GILBERT, PETER B.reporter.nih.gov
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile ImmunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,065,107August 23, 2023July 31, 2027MILICH, DAVID R.reporter.nih.gov
Recombinant Outer Membrane Vesicles as a Novel Adjuvant for a Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,755December 8, 2023November 30, 2026LOCHER, CHRISTOPHERreporter.nih.gov
PfSPZ Vaccine for Malaria: Towards a Successful Biologics License Application and CommercializationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,973,577February 15, 2004June 30, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
Cryopreservation of Anopheles EmbryosNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,928,928August 1, 2010January 31, 2024BILLINGSLEY, PETER F.reporter.nih.gov
Defining the immunogenic landscape of early mosquito-stage P. falciparum to accelerate malaria transmission-blocking vaccine discoveryNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,917,896July 5, 2024May 31, 2029SWEARINGEN, KRISTIAN EDWARDreporter.nih.gov
In-Vitro Culture of Plasmodium falciparum Sporozoites for Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,912,715February 15, 2010May 31, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Type-I Interferons drive cell-autonomous immunity to malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,887,500June 21, 2022May 31, 2027KURUP, SAMreporter.nih.gov
Virus-like Particle based malaria vaccines targeting vulnerable epitopes in the circumsporozoite proteinNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,841,511November 9, 2022October 31, 2027CHACKERIAN, BRYCE Creporter.nih.gov
Immunological characterization of the P. vivax DBPNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,773,948August 1, 2006March 31, 2026ADAMS, JOHN Hreporter.nih.gov
DISCOVERY AND PRECLINICAL DEVELOPMENT OF EFFICACIOUS P. vivax PRE-ERYTHROCYTIC STAGE MALARIA VACCINESNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,745,498November 20, 2020October 31, 2023HERRERA VALENCIA, SOCRATESreporter.nih.gov
Rationally-Designed, Spontaneous-Particleized Pfs48/45 for a Multivalent Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,631,717May 20, 2020April 30, 2026LOVELL, JONATHAN Freporter.nih.gov
Identification & Evaluation of Novel Malaria Anti-Gametocyte Transmission Blocking Vaccine Candidate AntigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,594,902August 29, 2019July 31, 2025NIXON, CHRISTIAN PARCHERreporter.nih.gov
Mechanisms of compromised CD8 T cell responses to vaccination in malaria experienced hostsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,507,165June 24, 2024April 30, 2029HARTY, JOHN Treporter.nih.gov
Multivalent mRNA-based malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,456,890August 1, 2024July 31, 2029BURNS, JAMES MATTHEWreporter.nih.gov
Exploiting cross-reactive, conserved epitopes in Plasmodium vivax to develop a vaccine against falciparum placental malaria.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,453,074March 10, 2020February 28, 2027YANOW, STEPHANIEreporter.nih.gov
Structural Vaccinology and Design of Novel Imunogens for Malaria Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,430,568February 1, 2018January 31, 2024GOLDBERG, DANIEL E.reporter.nih.gov
Human-informed data-driven development of next-generation T cell vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,424,256September 2, 2022August 31, 2026DOOLAN, DENISE L.reporter.nih.gov
Impacts of Environment, Host Genetics and Antigen Diversity on Malaria Vaccine EfficacyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,363,169March 1, 2018February 28, 2025BAILEY, JEFFREY A.reporter.nih.gov
Impact of early childhood malaria prevention on malaria risk at school entry (ERASE)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,276,157July 10, 2024May 31, 2029HARRISON, SHANNON TAKALAreporter.nih.gov
Inflammatory Suppression of Adaptive Immunity by Plasmodium MIFNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,256,250April 1, 2014April 30, 2025BUCALA, RICHARD Jreporter.nih.gov
Multi-target blood stage vaccine against Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,107,549December 13, 2019November 30, 2026RAJ, DIPAK KUMARreporter.nih.gov
PfSPZ Vaccine for Prevention of Plasmodium falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2022$988,772September 1, 2022June 30, 2024HOFFMAN, STEPHEN LEVreporter.nih.gov
Serological markers of natural immunity to Plasmodium falciparum infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$858,047July 12, 2021January 23, 2026FRIEDMAN-KLABANOFF, DEANNAreporter.nih.gov
Species-transcending prevention of mosquito vector infectionNIHNational Institute of Allergy and Infectious Diseases2025$832,071November 14, 2024October 31, 2029SATHER, D. NOAHreporter.nih.gov
mRNA-LNP vaccines targeting multiple stages and multiple species of human malaria parasiteNIHNational Institute of Allergy and Infectious Diseases2025$813,160December 26, 2024November 30, 2029KUMAR, NIRBHAYreporter.nih.gov
The function of atypical B cells in the immune response against malariaNIHNational Institute of Allergy and Infectious Diseases2025$812,704January 3, 2025December 31, 2026BUNNIK, EVELIEN MARGARETHAreporter.nih.gov
A systems analysis to understand the differential pharmacokinetics and protective efficacy of anti-malarial monoclonal antibodies in field trials.NIHNational Institute of Allergy and Infectious Diseases2025$781,241August 5, 2025July 31, 2030TRAN, TUAN MANHreporter.nih.gov
Mentoring in patient-oriented research in global healthNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$759,276January 11, 2016July 31, 2027LAUFER, MIRIAM K.reporter.nih.gov
Identifying the targets of protective immunity to severe falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2025$708,202December 20, 2024November 30, 2029KURTIS, JONATHAN D.reporter.nih.gov
Malaria vaccine evaluation in a novel infant NHP challenge modelNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$706,000November 4, 2022October 31, 2025SHEARS, MELANIE JANETreporter.nih.gov
Discovery and preclinical evaluation of Plasmodium falciparum and P. vivax coiled coil antigens for malaria vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$702,029January 3, 2020December 31, 2022HERRERA VALENCIA, SOCRATESreporter.nih.gov
Exploring the roles of acquired immunity and functional constraint in sculpting malaria antigenic diversity in a longitudinal cohortNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$694,822September 25, 2018October 31, 2024NEAFSEY, DANIEL Ereporter.nih.gov
Determinants of poor responsiveness to the booster dose of the RTS,S malaria vaccine in African childrenNIHNational Institute of Allergy and Infectious Diseases2025$690,500December 6, 2024November 30, 2029VALIM, CLARISSAreporter.nih.gov
Impact of early-life pathogen exposures on pre-erythrocytic malaria vaccine effectiveness in Kenyan infantsNIHNational Institute of Allergy and Infectious Diseases2025$682,200August 22, 2025July 31, 2030DOBBS, KATHERINE ROSEreporter.nih.gov
Tfh responses to novel vaccine candidates and protection from pediatric falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021$668,302August 11, 2017July 31, 2023KURTIS, JONATHAN D.reporter.nih.gov
Enhancing T and B cell responses to Plasmodium infection and vaccination via IL-15NIHNational Institute of Allergy and Infectious Diseases2024$606,767June 20, 2024April 30, 2025BURRACK, KRISTINA STOERMERreporter.nih.gov
Attenuation of Liquid Formulation for PfSPZ Vaccine by X-RayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$600,000April 12, 2021March 31, 2024JAMES, ERIC ROBERTreporter.nih.gov
In vitro bioreactor production of a genetically modified late liver stage-arresting replication competent Plasmodium falciparum sporozoite vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$600,000June 3, 2022May 31, 2025SIM, B. KIM LEEreporter.nih.gov
Conditional male lethal Anopheles stephensi line for the efficient manufacture of malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$599,951February 14, 2023January 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
Delivery of a candidate AgTRIOVx malaria vaccine by thermostable microneedle patchesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$599,740June 1, 2024May 31, 2027ANTHONY, KAREN G.reporter.nih.gov
The Development and Function of Plasmodium-specific memory B cellsNIHNational Institute of Allergy and Infectious Diseases2021$596,609December 16, 2016November 30, 2022PEPPER, MARIONreporter.nih.gov
Memory T follicular helper cell kinetics and localization during recall immune responses to tetanus vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$586,904August 12, 2019July 31, 2024FROSCH, ANNE ELIZABETH PARKERreporter.nih.gov
The Germinal Center and T cell help in Three Phases of Clearance of PlasmodiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$564,054November 1, 2017July 15, 2022STEPHENS, ROBINreporter.nih.gov
Modularizing manufacture of PfSPZ vaccines: ookinete production for PfSPZ manufacture in mosquitoes and in vitroNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$559,942September 6, 2023August 31, 2025HOFFMAN, STEPHEN LEVreporter.nih.gov
Directed in vivo assembly of a robust biopolymer particle-based multistage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2025$549,032September 10, 2025August 31, 2028REHM, BERNDreporter.nih.gov
Antigen discovery for transmission-blocking vaccines in Plasmodium vivaxNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$540,000April 6, 2020February 28, 2025CAO, YAMINGreporter.nih.gov
The Skin Phase of Malaria InfectionNIHNational Institute of Allergy and Infectious Diseases2021$536,335July 6, 2017June 30, 2024SINNIS, PHOTINIreporter.nih.gov
Evaluating the impact of pre-existing humoral immunity on hepatocyte deathNIHNational Institute of Allergy and Infectious Diseases2025$516,175June 23, 2025May 31, 2027KAUSHANSKY, ALEXISreporter.nih.gov
Identifying the targets of protective immunity to severe falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2023$500,144September 4, 2023August 31, 2024KURTIS, JONATHAN D.reporter.nih.gov
Human-informed data-driven development of next-generation T cell vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2022$495,904September 2, 2022January 1, 2023DOOLAN, DENISE L.reporter.nih.gov
Generating a novel dual stage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$485,375September 24, 2021August 31, 2023PEPPER, MARIONreporter.nih.gov
Multiplex analysis of IgA and IgG antibody responses to early childhood malaria infections to inform vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$482,617May 2, 2023April 30, 2026BERRY, ANDREAreporter.nih.gov
A Chemical Vaccine for MalariaNIHNational Institute of Allergy and Infectious Diseases2021$473,670September 19, 2019August 31, 2023SHAPIRO, THERESA Areporter.nih.gov
Designing a diversity-covering multiantigen multi-strain malaria vaccineNIHNational Heart, Lung, and Blood Institute2021 to 2023$457,659August 2, 2019July 31, 2025OUATTARA, AMEDreporter.nih.gov
Effect of gut microbiota composition on malaria vaccine-induced immune responsesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$449,728June 24, 2024April 30, 2026SCHMIDT, NATHANreporter.nih.gov
Developing a barcoded malaria parasite panel to assess broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$438,625June 29, 2022November 30, 2024DURAISINGH, MANOJ Treporter.nih.gov
Investigating gene regulatory networks in immune cells of children who differ in susceptibility to malaria infection using single-cell approachesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$432,218January 1, 2021June 30, 2024TRAN, TUAN MANHreporter.nih.gov
High throughput chemoenzymatic synthesis of antimalarial compoundsNIHNational Center for Complementary & Integrative Health2022 to 2023$429,000September 1, 2022August 31, 2025NARAYAN, ALISONreporter.nih.gov
Design and Evaluation of a Plasmodium vivax ultra-dense peptide arrayNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$424,875March 15, 2021February 28, 2023SERRE, DAVIDreporter.nih.gov
Intracellular-acting antibodies for the prevention of malaria liver stage infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$423,500November 4, 2022October 31, 2024WILDER, BRANDON KEITHreporter.nih.gov
Integrating a pre-erythrocytic component into a multistage malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$416,125November 12, 2020October 31, 2023BURNS, JAMES MATTHEWreporter.nih.gov
Longitudinal Antibody Profiles Correlated with Protection from Malaria in MalawiNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$415,919January 8, 2021December 31, 2023VALIM, CLARISSAreporter.nih.gov
Evaluation of Immunodominant fragments of PfGARP for malaria vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2025$412,500July 3, 2025June 30, 2027RAJ, DIPAK KUMARreporter.nih.gov
Multi-target blood stage vaccine against Plasmodium falciparumNIHNational Institute of Allergy and Infectious Diseases2021$406,250December 13, 2019November 30, 2021RAJ, DIPAK KUMARreporter.nih.gov
Anopheles FBG: a novel malaria transmission-blocking vaccine targetNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$384,730November 8, 2022October 31, 2025LI, JUNreporter.nih.gov
Impact of P. falciparum diversity on transmission reducing immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$382,428July 1, 2018June 30, 2024COHEE, LAUREN Mreporter.nih.gov
Synthesizing immunoinformatics and genetic epidemiology to identify signatures of natural functional immunity to malaria parasitesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$369,354March 1, 2023February 29, 2028MARKWALTER, CHRISTINEreporter.nih.gov
Development of novel malaria pre-erythrocytic vaccine antigens targeting Plasmodium sporozoite liver infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$368,224January 4, 2023December 31, 2025CHA, SUNG-JAEreporter.nih.gov
Large Scale systematic priorization of Plasmodium vivax blood stage vaccine antigensNIHNational Institute of Allergy and Infectious Diseases2021$318,040February 14, 2018January 31, 2023RAYNER, JULIAN CHARLESreporter.nih.gov
Mathematical modeling of immune response to malariaNIHNational Institute of General Medical Sciences2021$303,690March 1, 2017February 28, 2023GANUSOV, VITALY V.reporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stage.NIHNational Institute of Allergy and Infectious Diseases2021$300,000April 21, 2020March 31, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
Enhancement of gametocytogenesis in Plasmodium falciparum by genetic engineering for improved PfSPZ Vaccine ManufactureNIHNational Institute of Allergy and Infectious Diseases2021$299,994August 17, 2020July 31, 2023HOFFMAN, STEPHEN LEVreporter.nih.gov
PfAg, a multivalent peptide vaccine against malariaNIHNational Institute of Allergy and Infectious Diseases2025$299,954September 15, 2025August 31, 2027CHUANG, YU-MINreporter.nih.gov
A vaccine targeting mosquito metabolic pathways to eradicate malariaNIHNational Institute of Allergy and Infectious Diseases2025$299,644September 23, 2025August 31, 2027CHUANG, YU-MINreporter.nih.gov
E. coli platform for expression of low-cost malaria fusion proteinsNIHNational Institute of Allergy and Infectious Diseases2024$297,809January 1, 2024June 30, 2025LEES, ANDREWreporter.nih.gov
Safety, immunogencity, and efficacy of PfSPZ LARC2 malaria vaccine in malaria-exposed adults and childrenNIHNational Institute of Allergy and Infectious Diseases2024$250,796June 12, 2024May 31, 2025LAURENS, MATTHEW BRENTreporter.nih.gov
Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse PathogensNIHNational Institute of Allergy and Infectious Diseases2021$248,674April 1, 2003March 31, 2022GILBERT, PETER B.reporter.nih.gov
Role of cytolytic ZEB2+ memory CD4+ T cells in protection against liver stage malariaNIHNational Institute of Allergy and Infectious Diseases2025$244,440January 14, 2025December 31, 2026LAUVAU, GREGOIRE STEPHANEreporter.nih.gov
Biological Equivalence of In Vitro Plasmodium falciparum Culture for Practical Malaria Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021$217,162September 21, 2020August 31, 2023AVRIL, MARIONreporter.nih.gov
Investigating Plasmodium vaccination in 'dirty' miceNIHNational Institute of Allergy and Infectious Diseases2025$205,125November 13, 2024October 31, 2026BURRACK, KRISTINA STOERMERreporter.nih.gov
Pan-vaccine Analysis to Test the Impact of Cytomegalovirus on Vaccine EfficacyNIHNational Institute of Allergy and Infectious Diseases2021$201,875June 1, 2020May 31, 2022HU, ZICHENGreporter.nih.gov
Systems Antibody Immunology of the Malaria Sporozoite VaccineNIHNational Institute of Allergy and Infectious Diseases2024$195,480January 16, 2024August 31, 2024HERMAN, JONATHAN DAVIDreporter.nih.gov
Systems Antibody Immunology of the Malaria Sporozoite VaccineNIHNational Institute of Allergy and Infectious Diseases2025$195,480January 16, 2024December 31, 2028HERMAN, JONATHAN DAVIDreporter.nih.gov
Determining the mechanism of antibody-mediated parasite clearance in Plasmodium blood stage infectionNIHNational Institute of Allergy and Infectious Diseases2021$193,438April 1, 2020March 31, 2022HART, GEOFFREY Treporter.nih.gov
Defining clinical and sterile immunity to Plasmodium falciparum infection using systems biology approachesNIHNational Institute of Allergy and Infectious Diseases2021$185,224February 10, 2017January 31, 2023TRAN, TUAN MANHreporter.nih.gov
Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical MalariaNIHNational Institute of Allergy and Infectious Diseases2025$184,109December 19, 2024November 30, 2026DOBBS, KATHERINE ROSEreporter.nih.gov
Exploring the parasite genomics of severe falciparum malaria in MozambiqueNIHNational Institute of Allergy and Infectious Diseases2021$183,677March 5, 2020February 28, 2023WINZELER, ELIZABETH Areporter.nih.gov
Hemozoin and liver stage malaria vaccine efficacyNIHNational Institute of Allergy and Infectious Diseases2025$183,276August 1, 2025July 31, 2027HASSERT, MARIAH Areporter.nih.gov
Protein microarray antibody responses to P. falciparum in a human challenge modelNIHNational Institute of Allergy and Infectious Diseases2021$183,004February 6, 2017January 31, 2024BERRY, ANDREAreporter.nih.gov
Determinants of Vaccine Responses in Low-Income Countries (LICs)NIHNational Institute of Allergy and Infectious Diseases2025$176,738September 1, 2025August 31, 2030VALIM, CLARISSAreporter.nih.gov
Group 1 CD1-restricted human T cells induced by a whole sporozoite-based malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021$162,000March 10, 2020February 28, 2022TSUJI, MORIYAreporter.nih.gov
Validation and characterization of antibody responses to Plasmodium falciparum antigens identified by protein array screeningNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$158,500February 10, 2021January 31, 2024TRAN, TUAN MANHreporter.nih.gov
Understanding and overcoming Plasmodium-specific immune evasion mechanismsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$156,980June 1, 2024May 31, 2026MCDOUGAL, COURTNEYreporter.nih.gov
Design of a B cell tetramer to track PfMSP2-specific B cellsNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$152,000November 1, 2021October 31, 2023STUMHOFER, JASON Sreporter.nih.gov
Modeling mutant PfCRT-mediated drug transport to predict the emergence of piperaquine-resistant Plasmodium falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$140,482January 1, 2021December 31, 2023HAGENAH, LAURA MARIEreporter.nih.gov
The Kinetics and Dynamics of Functional Immune Responses to Plasmodium falciparum StrainsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$83,460July 1, 2024June 30, 2027HAGADORN, KELLYreporter.nih.gov
Analyzing the function and antibody-mediated inhibition of the malaria vaccine candidate PF3D7_1136200NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$81,086August 1, 2024September 22, 2027GARZA, ROLANDOreporter.nih.gov
Employing Genetic and Genomic Surveillance to Reveal Mechanisms of Malaria Parasite PersistanceNIHFogarty International Center2021$73,070September 28, 2016December 31, 2022BEI, AMY KRISTINEreporter.nih.gov
Defining molecular and cellular mechanisms of protection from malaria infection by PfCSP-targeting antibodiesNIHNational Institute of Allergy and Infectious Diseases2021$66,390June 15, 2021June 14, 2022MARTIN, GREGORY Mreporter.nih.gov
Improving the Translational Potential of a Prime-and-Trap Malaria VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$54,332September 10, 2022September 11, 2023WATSON, FELICIAreporter.nih.gov
Molecular and cellular properties of broad and protective immune responses to the Plasmodium falciparum variant surface antigen responsible for severe malariaNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$45,919May 1, 2022June 2, 2023REYES, RAPHAEL ANTHONYreporter.nih.gov
Dissecting compromised efficacy of liver-stage malaria immunizations in hosts with a history of blood-stage malariaNIHNational Institute of Allergy and Infectious Diseases2022$26,156July 28, 2022December 2, 2022DREWRY, LISA Lreporter.nih.gov
Infectious Diseases in Africa: Correlates of Protection, Lessons from Vaccines and Natural Infection StudiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$25,001March 3, 2020February 28, 2023FERRARI, GUIDOreporter.nih.gov
Development of novel malaria pre-erythrocytic vaccine antigens targeting Plasmodium sporozoite liver infectionNIHNational Institute of Allergy and Infectious Diseases2023$24,188January 4, 2023March 17, 2023CHA, SUNG-JAEreporter.nih.gov
Malaria: Mechanisms of Immunity & ProtectionNIHNational Institute of Allergy and Infectious Diseases2025$7,500January 23, 2025December 31, 2025SHEPPARD, TERRY L.reporter.nih.gov
2023 International Society for Vaccines (ISV) Annual Congress, October 22-25, Lausanne, SwitzerlandNIHNational Institute of Allergy and Infectious Diseases2023$5,000August 22, 2023July 31, 2024WEINER, DAVID B.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Sanaria, Inc.Rockville, MD17$35.3 million0$0
University of WashingtonSeattle, WA8$23.6 million0$0
Seattle Children's HospitalSeattle, WA6$16.4 million0$0
Kaiser Foundation Research InstituteOakland, CA1$14.2 million0$0
University of California, San FranciscoSan Francisco, CA3$9.1 million0$0
University of South FloridaTampa, FL4$8.1 million0$0
Oregon Health & Science UniversityPortland, OR3$7.5 million0$0
University of Maryland BaltimoreBaltimore, MD10$7.2 million0$0
Massachusetts General HospitalBoston, MA2$6.8 million0$0
Brown UniversityProvidence, RI6$5.2 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM2$4.6 million0$0
Yale UniversityNew Haven, CT4$4.2 million0$0
University of IowaIowa City, IA4$4.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA1$3.9 million0$0
Johns Hopkins UniversityBaltimore, MD4$3.8 million0$0
Duke UniversityDurham, NC3$3.7 million0$0
University of Texas HLTH Science CenterSan Antonio, TX4$3.7 million0$0
University of Vermont & ST Agric CollegeBurlington, VT1$3.4 million0$0
Stanford UniversityStanford, CA1$3 million0$0
Lumen Bioscience, Inc.Seattle, WA1$2.9 million0$0
Case Western Reserve UniversityCleveland, OH1$2.8 million0$0
Columbia University Health SciencesNew York, NY3$2.8 million0$0
Leiden University Medical CenterLeiden1$2.6 million0$0
Caucaseco Scientific Research CenterCali2$2.4 million0$0
University of MinnesotaMinneapolis, MN2$2.3 million0$0
Fred Hutchinson Cancer CenterSeattle, WA1$2.1 million0$0
Vaccine Research Institute of San DiegoSan Diego, CA1$2.1 million0$0
Indiana University IndianapolisIndianapolis, IN5$2 million0$0
Versatope Therapeutics, Inc.Lowell, MA1$2 million0$0
Institute for Systems BiologySeattle, WA1$1.9 million0$0
University of Georgia Research Foundation IncAthens, GA1$1.9 million0$0
Drexel UniversityPhiladelphia, PA2$1.9 million0$0
SUNY at BuffaloAmherst, NY1$1.6 million0$0
University of AlbertaEdmonton1$1.5 million0$0
Washington UniversitySaint Louis, MO1$1.4 million0$0
University of QueenslandBrisbane1$1.4 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN3$1.4 million0$0
Boston University Medical CampusBoston, MA3$1.3 million0$0
L2 Diagnostics, LLCNew Haven, CT3$1.2 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA2$1.1 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH2$866,3090$0
George Washington UniversityWashington, DC1$813,1600$0
University of Texas Med BR GalvestonGalveston, TX1$564,0540$0
Griffith UniversityQueensland1$549,0320$0
China Medical UniversityShenyang1$540,0000$0
James Cook University of No QueenslandTownsville1$495,9040$0
University of Michigan at Ann ArborAnn Arbor, MI1$429,0000$0
Florida International UniversityMiami, FL1$384,7300$0
Mercer UniversityMacon, GA1$368,2240$0
University of CambridgeCambridge1$318,0400$0
University of Tennessee KnoxvilleKnoxville, TN1$303,6900$0
Fina Biosolutions, LLCRockville, MD1$297,8090$0
Fred Hutchinson Cancer Research CenterSeattle, WA1$248,6740$0
Albert Einstein College of MedicineBronx, NY1$244,4400$0
Malarvx, Inc.Seattle, WA1$217,1620$0
Brigham and Women's HospitalBoston, MA1$195,4800$0
University of California Los AngelesLos Angeles, CA1$195,4800$0
University of California, San DiegoLa Jolla, CA1$183,6770$0
Univ of Arkansas for Med ScisLittle Rock, AR1$152,0000$0
Scripps Research Institute, theLa Jolla, CA1$66,3900$0
Keystone SymposiaSilverthorne, CO1$7,5000$0
International Society of VaccinesWorcester, MA1$5,0000$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202563$38,804,7060$0
202463$39,019,0210$0
202371$42,254,4830$0
202272$47,236,9420$0
202170$48,683,0010$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 139 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 139 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 139 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 139 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 139 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 139 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 139 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 139 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 139 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 139 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 139 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 139 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 139 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 139 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 139 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 139 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 139 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.855May 7, 2027Not listedSame assistance listing 93.855 as 139 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.