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Data / Research funding / Lewy Body Dementia

Lewy Body Dementia: 283 NIH awards ($469.7M) to 93 organizations

283 NIH awards ($469.7M) in the NIH spending category Lewy Body Dementia, to 93 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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283 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Dementia with Lewy BodiesNIHNational Institute on Aging2021 to 2023$29,498,064May 15, 2021April 30, 2025CAGGIANO, ANTHONY Oreporter.nih.gov
A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Mild-to-Moderate Dementia with Lewy Bodies (DLB)NIHNational Institute on Aging2023 to 2025$21,072,036February 1, 2023January 31, 2026ALAM, JOHNreporter.nih.gov
Mayo Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$18,486,241July 1, 2019April 30, 2029BOEVE, BRADLEY Freporter.nih.gov
1Florida Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$13,348,245June 15, 2020April 30, 2027SMITH, GLENN E.reporter.nih.gov
Longitudinal Imaging Biomarkers of Prodromal DLBNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,821,041September 25, 2017August 31, 2027KANTARCI, KEJALreporter.nih.gov
Dementia with Lewy Bodies ConsortiumNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$6,563,373September 30, 2016August 31, 2027LEVERENZ, JAMES BRUCEreporter.nih.gov
Digital Health Technologies for Monitoring Motor Function in Progressive Supranuclear Palsy and Dementia with Lewy BodiesNIHNational Institute on Aging2025$5,174,076September 1, 2025August 31, 2029VAZIRI, ASHKANreporter.nih.gov
Novel Protein Biomarkers of Corticolimbic Pathophysiology in Lewy body DementiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$4,943,234September 15, 2022June 30, 2027SEYFRIED, NICHOLAS THOMASreporter.nih.gov
Assessing Novel Biomarkers for Cognitive Fluctuations in DLBNIHNational Institute of Neurological Disorders and Stroke2025$4,924,374September 1, 2025July 31, 2029PILLAI, JAGAN AYYAPPANreporter.nih.gov
Brain mitochondrial PET imaging and 31P-MR spectroscopy to dissect the role of mitochondrial dysfunction in bioenergetic dysregulation in Dementia with Lewy Bodies pathogenesisNIHNational Institute on Aging2023 to 2025$4,683,243September 15, 2023May 31, 2029BERMAN, SARAH Breporter.nih.gov
African Ancestry and the Genomic Architecture of AD and Other Common Neurodegenerative Disease NeuropathologiesNIHNational Institute on Aging2021 to 2023$4,504,699September 15, 2016May 31, 2024BENNETT, DAVID ALANreporter.nih.gov
Structural Biology of Alpha-Synuclein in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2023$4,231,530September 30, 2018August 31, 2026KOTZBAUER, PAUL Treporter.nih.gov
Peripheral Tissue Biomarker for Premortem Diagnosis of Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$4,170,328December 15, 2021June 30, 2026CHEN, SHU G.reporter.nih.gov
Skin biomarkers for diagnosing and characterizing AD and ADRDNIHNational Institute on Aging2021 to 2025$3,834,262September 30, 2021June 30, 2027KRAUS, ALLISON Lreporter.nih.gov
Synucleinopathies – Novel Targets in Early Diagnosis, Pathophysiology, and Therapeutic ApproachNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,826,830August 1, 2015June 30, 2027SINGER, WOLFGANGreporter.nih.gov
Elucidating the Biological Differences Between Distinct Fibrillar and Non-Fibrillar Alpha-Synuclein Inclusions in Human Stem-Cell ModelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,706,946July 1, 2020April 30, 2026KHURANA, VIKRAMreporter.nih.gov
IND enabling CMC/safety/toxicology studies, submission of IND and pilot Phase 1 clinical trial with PV-1950R vaccine for Lewy Body Dementia (LBD)NIHNational Institute on Aging2024 to 2025$3,640,661June 5, 2024May 31, 2029AGADJANYAN, MICHAEL Greporter.nih.gov
Dissect the mechanisms of selective regional vulnerability in Lewy Body Dementias via comparative snRNA-seq analysisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,568,423July 15, 2021May 31, 2027ZHAO, GUOYANreporter.nih.gov
Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)NIHNational Institute on Aging2021 to 2023$3,567,627March 15, 2019November 30, 2025DAMS-O'CONNOR, KRISTENreporter.nih.gov
Region-Specific Vulnerability of the Lewy Body Dementia's BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,557,900August 1, 2021June 30, 2027NA, CHAN-HYUNreporter.nih.gov
More than a Movement Disorder: Applying Palliative Care to Parkinson's Disease and Lewy Body DementiasNIHNational Institute of Nursing Research2021 to 2025$3,433,868September 15, 2016September 30, 2026KLUGER, BENZI Mreporter.nih.gov
A randomized, double blind, placebo-controlled study to evaluate the impact of Nilotinib treatment on safety, tolerability, pharmacokinetics and biomarkers in Dementia with Lewy Bodies (DLB)NIHNational Institute on Aging2021 to 2022$3,210,062July 1, 2019April 30, 2025MOUSSA, CHARBELreporter.nih.gov
Spatial organization and conformational ensembles of amyloids inside cellsNIHNational Institute of Neurological Disorders and Stroke2025$3,178,675August 13, 2025July 31, 2029FREDERICK, KENDRA KINGreporter.nih.gov
Deep Phenotypic Characterization of Prodromal Dementia with Lewy BodiesNIHNational Institute on Aging2022$3,171,435September 30, 2022August 31, 2025GALVIN, JAMES Ereporter.nih.gov
Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease and Related DisordersNIHNational Institute on Aging2022 to 2025$3,140,565June 1, 2022March 31, 2027KREILING, JILLreporter.nih.gov
Preclinical Markers of ParkinsonismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,073,020August 1, 2021June 30, 2027VAILLANCOURT, DAVID Ereporter.nih.gov
Production and Distribution of well-characterized polymorphic variants of alpha-synuclein aggregatesNIHNational Institute on Aging2022 to 2025$3,065,392September 30, 2022May 31, 2027SOTO, CLAUDIOreporter.nih.gov
Anxiety and depression in a nonhuman primate model of synucleinopathyNIHNational Institute of Neurological Disorders and Stroke2025$3,064,072August 4, 2025July 31, 2029EMBORG, MARINAreporter.nih.gov
Investigating the Causal Role of Particulate Matter Components on Lewy Body Dementia: Integrating Epidemiologic and Mechanistic EvidenceNIHNational Institute of Neurological Disorders and Stroke2025$3,013,265August 1, 2025July 31, 2029PARKS, ROBBIE Mreporter.nih.gov
Differential diagnosis of Parkinson's and multiple system atrophy in non-human primate models using a novel a-synuclein retinal contrast agent and AI-assisted analyticsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,977,682September 23, 2021August 31, 2024SARRAF, STELLAreporter.nih.gov
Single-Nuclei Multiomic Analysis of DLB ProgressionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,970,479August 17, 2022July 31, 2027KIM, YOON-SEONGreporter.nih.gov
Multi-site longitudinal Integrated Neurocognitive and Sleep-Behavior Profiler for the Endophenotypic Classification of Dementia Subtypes (INSPECDS)NIHNational Institute on Aging2022 to 2024$2,933,352September 30, 2016May 31, 2026BERKA, CHRISreporter.nih.gov
Development of a Blood-based Test for Identifying Synucleinopathy in Patients with DementiaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,919,989September 23, 2022August 31, 2026EITAN, EREZreporter.nih.gov
Brainstem-based imaging biomarkers of premanifest synucleinopathyNIHNational Institute on Aging2021 to 2024$2,913,904May 15, 2020April 30, 2026BIANCIARDI, MARTAreporter.nih.gov
Vitamin K and D and Cognitive Impairment in Older AdultsNIHNational Institute on Aging2022 to 2025$2,723,572September 1, 2016March 31, 2027BOOTH, SARAH LOUISEreporter.nih.gov
Structure-function relationships in alpha-synuclein strain biologyNIHNational Institute of Neurological Disorders and Stroke2025$2,674,385August 15, 2025July 31, 2029WOERMAN, AMANDA L.reporter.nih.gov
Identifying Factors Predicting ACcurately End-of-Life in Dementia with Lewy Bodies and Promoting Quality End-of-Life Experiences: the PACE-DLB StudyNIHNational Institute on Aging2021 to 2024$2,662,829September 15, 2020April 30, 2026ARMSTRONG, MELISSA JOreporter.nih.gov
Adding technology that will enhance commercialization of our neuroscience-based innovative assistive technology platform for living with Alzheimer's disease and Alzheimer's disease related dementiaNIHNational Institute on Aging2024 to 2025$2,660,575May 15, 2024April 30, 2027GOLDEN, MATTHEWreporter.nih.gov
Microbiome-gut-brain dysfunction in prodromal and symptomatic Lewy body diseasesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,637,479August 1, 2023July 31, 2028RYMAN, SEPHIRAreporter.nih.gov
Developing Protein-based MRI Biomarkers for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2024$2,630,332September 15, 2020May 31, 2026ZHOU, JINYUANreporter.nih.gov
The impact of early Tau pathology on cognitive progression and neuropsychiatric symptoms in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,609,788September 20, 2019August 31, 2025POSTON, KATHLEEN LOMBARDreporter.nih.gov
Neurostimulation of the Nucleus Basalis of Meynert for the cognitive-motor syndrome in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,549,857August 19, 2022July 31, 2027BRONTE-STEWART, HELENreporter.nih.gov
Citalopram as a posterior cortical protective therapy in Parkinson diseaseNIHNational Institute on Aging2021 to 2024$2,545,093August 15, 2020April 30, 2026KOTAGAL, VIKASreporter.nih.gov
Investigating physiologic and pathophysiologic connections between the Parkinson's disease protein alpha-synuclein and RNA binding proteinsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,493,768August 1, 2023July 31, 2028KHURANA, VIKRAMreporter.nih.gov
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and functionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,474,168August 1, 2015April 30, 2027MAZZULLI, JOSEPH Rreporter.nih.gov
Imaging epigenetic dysregulation in the Lewy body dementias with [11C]MartinostatNIHNational Institute on Aging2023 to 2025$2,463,125May 1, 2023March 31, 2028GOMPERTS, STEPHEN N.reporter.nih.gov
Innovating high-resolution novel imaging approaches to elucidate mechanisms of prion-like spreadingof neurodegenerative diseaseNIHNational Institute on Aging2021 to 2024$2,409,422May 1, 2020February 28, 2026LEE, JIN HYUNGreporter.nih.gov
A Diagnostic Test for Dementia with Lewy BodiesNIHNational Institute on Aging2022 to 2023$2,408,271April 1, 2022March 31, 2026LEVINE, TODDreporter.nih.gov
Interaction between microvascular function and CSF clearance in Lewy body dementiaNIHNational Institute on Aging2023$2,387,139June 1, 2023May 31, 2026HUA, JUNreporter.nih.gov
Dissecting the Etiology of The Lewy Body DementiasNIHNational Institute of Neurological Disorders and Stroke2022$2,383,188May 1, 2022April 30, 2025FINKBEINER, STEVEN Mreporter.nih.gov
The Impact of Beta- and Gamma-synucleins on Alpha-synuclein's Synaptic FunctionNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,342,275May 1, 2023March 31, 2024BURRE, JACQUELINEreporter.nih.gov
Neuroplasticity and the emergence of motor and cognitive deficits in prodromal synucleinopathyNIHNational Institute of Neurological Disorders and Stroke2022$2,336,166August 15, 2022July 31, 2025MACKINNON, COLUM Dreporter.nih.gov
Blinded Comparison of Different Alpha-Synuclein Seeding Assays as Cutaneous Biomarkers of Lewy Body DementiasNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,335,086September 15, 2021August 31, 2025BEACH, THOMAS Greporter.nih.gov
Investigations of Dementia in Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$2,332,494September 23, 2021August 31, 2026PERLMUTTER, JOEL SYNESreporter.nih.gov
Protein Aggregation and Neurotransmitter Deficits in Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,315,618August 1, 2016June 30, 2027KOTZBAUER, PAUL Treporter.nih.gov
Leveraging a Natural Experiment to Determine the Effects of Integrated Palliative Care on Health Service Outcomes and Disparities in Parkinson Disease and Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2023$2,307,536August 21, 2023July 31, 2026WILLIS, ALLISONreporter.nih.gov
Determine the role of atmospheric particulate matter pollutants in contributing to Lewy Body DementiaNIHNational Institute on Aging2023$2,296,059April 15, 2023March 31, 2026MAO, XIAOBOreporter.nih.gov
Novel fibril-selective nanobody-based agents targeting intracellular and extracellular α-synuclein aggregates and prion-like propagation induced dementiaNIHNational Institute of Neurological Disorders and Stroke2024$2,280,379September 19, 2024August 31, 2027WANG, WENJINGreporter.nih.gov
Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM sleep Behavior DisorderNIHNational Institute on Aging2025$2,276,803September 1, 2023August 31, 2028HOWELL, MICHAEL Jreporter.nih.gov
Propagation of Lewy pathology in Parkinson's and related disordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,263,224March 13, 2015November 30, 2026LUK, KELVIN Creporter.nih.gov
Heterochronic Blood Exchange Inhibits α?Synucleinopathy through Modulating Plasma Protein's Mediation on Pathological α?Synuclein SpreadingNIHNational Institute on Aging2021 to 2025$2,261,713September 30, 2021May 31, 2027MAO, XIAOBOreporter.nih.gov
Molecular and Network Analyses of Lewy Body Dementia PathogenesisNIHNational Institute on Aging2021$2,252,599September 5, 2021August 31, 2024CHIN, LIH-SHENreporter.nih.gov
Worldwide Tractometry Initiative to Investigate Brain Microstructure, Cognitive Impairment & Dementia in Parkinsons DiseaseNIHNational Institute of Neurological Disorders and Stroke2024$2,243,095June 1, 2024May 31, 2027THOMPSON, PAUL Mreporter.nih.gov
Vulnerability of the ascending arousal network to alpha-synuclein pathologyNIHNational Institute of Neurological Disorders and Stroke2024$2,234,905September 18, 2024August 31, 2027ALDRIDGE, GEORGINAreporter.nih.gov
Peripheral Biomarkers for Early Diagnosis of Mixed Pathologies in AD/ADRDNIHNational Institute on Aging2023 to 2025$2,219,859June 1, 2023February 29, 2028CHEN, SHU G.reporter.nih.gov
Identification and Verification of S-Nitrosylated Proteins in Bodily Fluids as Biomarkers for Parkinson's Disease and Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2021$2,199,931July 1, 2021June 30, 2025NAKAMURA, TOMOHIROreporter.nih.gov
Neurostimulation of the Nucleus Basalis of Meynert for the cognitive-motor syndrome in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,192,915August 19, 2022July 31, 2024BRONTE-STEWART, HELENreporter.nih.gov
How Serine-129 Phosphorylation Status Affects the Spreading of α-Synuclein Pathology in Vivo: a Study in Knock-in AnimalsNIHNational Institute of Neurological Disorders and Stroke2023$2,192,716August 1, 2023July 31, 2026DETTMER, ULFreporter.nih.gov
Mechanisms of gene regulation and RNA processing in synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,181,405July 1, 2020June 30, 2025MAZZULLI, JOSEPH Rreporter.nih.gov
PERSEVERE in Lewy Body Dementia: A Randomized, Controlled Trial of Peer Mentor Support and Caregiver EducationNIHNational Institute on Aging2023 to 2025$2,167,105August 15, 2023June 30, 2028FLEISHER, JORI ERINreporter.nih.gov
Biomarkers of cognitive decline in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,148,559September 19, 2019June 30, 2024CHEN-PLOTKIN, ALICE Sreporter.nih.gov
Assessing skin biomarkers for preclinical diagnosis of PD and non-PD ParkinsonismNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,147,422August 15, 2019May 31, 2025KONG, QINGZHONGreporter.nih.gov
α-Synuclein strain properties are associated with diagnosis of and progression to Parkinson's disease with dementiaNIHNational Institute of Neurological Disorders and Stroke2022$2,133,267March 1, 2022February 28, 2025MAO, XIAOBOreporter.nih.gov
Polo-like-kinase-2-dependent α-Synuclein Serine-129 Phosphorylation: a Physiological RoleDuring Synaptic ActivityNIHNational Institute of Neurological Disorders and Stroke2022$2,121,853July 15, 2022April 30, 2025DETTMER, ULFreporter.nih.gov
Use of wearable sensors to improve the early diagnosis of DLBNIHNational Institute on Aging2022 to 2024$2,120,721September 15, 2019August 31, 2026TSUANG, DEBBY WENreporter.nih.gov
Slow wave sleep as a biomarker of rehabilitation-induced cognitive improvement in Parkinson's diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,113,374April 1, 2021March 31, 2027AMARA, AMY WILLISreporter.nih.gov
Mechanisms of Synaptic Dysfunction in Parkinson's and Other Synuclein-Linked DiseasesNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,092,085June 1, 2022May 31, 2025MORGAN, JENNIFER REBECCAreporter.nih.gov
S-Nitrosylation-Dependent Pathological Spread of Abnormal Proteins in Frontotemporal Dementia and Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2021$2,081,944August 1, 2021July 31, 2024NAKAMURA, TOMOHIROreporter.nih.gov
Decoding the BETA-arrestin2-LMBRD2 cascade in ALPHA-synuclein pathogenesis.NIHNational Institute of Neurological Disorders and Stroke2024$2,069,215August 6, 2024July 31, 2027WOO, JUNGA "ALEXA"reporter.nih.gov
Peripheral Tissue Biomarker for Premorten Diagnosis of Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2021$2,065,446September 1, 2020June 30, 2025CHEN, SHU G.reporter.nih.gov
MicroRNAs in CNS-derived extracellular microvesicles as peripheral blood biomarkers for Alzheimer diseaseNIHNational Institute on Aging2021 to 2023$2,025,805March 1, 2019June 30, 2025SHI, MINreporter.nih.gov
Identifying genetically driven gene dysregulation in Alzheimer's disease and related dementias using statistical data integrationNIHNational Institute on Aging2023 to 2025$1,999,058April 1, 2023December 31, 2027VOLOUDAKIS, GEORGIOSreporter.nih.gov
Prospective memory impairment in Parkinson disease-related cognitive decline: Intervention and mechanismsNIHNational Institute on Aging2021 to 2024$1,964,673September 15, 2020May 31, 2026FOSTER, ERINreporter.nih.gov
Investigating the role of lipid metabolism in protein aggregation and neurodegenerative disease progressionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,957,052December 1, 2020November 30, 2026DAVIS, MARIE YNEZreporter.nih.gov
Elucidating the role of NK cells in Lewy body diseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,936,429February 1, 2021March 31, 2027LEE, JAE-KYUNG JAMISEreporter.nih.gov
Smartphone phenotype collection for diagnostic screening of mild cognitive impairmentNIHNational Institute on Aging2021 to 2022$1,929,269September 30, 2018May 31, 2025ARMENTROUT, STEVEN Lreporter.nih.gov
Role of GlcSph in cognitive deficits in Lewy body dementiasNIHNational Institute on Aging2023 to 2025$1,911,743May 15, 2023March 31, 2028VOLPICELLI-DALEY, LAURA A.reporter.nih.gov
Towards Generating a Multimodal and Multivariate Classification Model from Imaging and Non-Imaging Measures for Accurate Diagnosis and Monitoring of Dementia in Parkinsons diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,881,677September 1, 2020June 30, 2026MISHRA, VIRENDRA Rreporter.nih.gov
Linear predictive coding of EEG Activity for Diagnosis of Parkinson's Disease (LEAD-PD)NIHNational Institute of Neurological Disorders and Stroke2023$1,876,731June 1, 2023May 31, 2026UC, ERGUN Yreporter.nih.gov
Airborne metals, neurodegeneration, and dementia in the Adult Changes in Thought studyNIHNational Institute of Environmental Health Sciences2023 to 2025$1,847,274September 15, 2023June 30, 2028SUH, HELENreporter.nih.gov
Studying Aggregation in Neurodegenerative Disease using Synthetic ProteinsNIHNational Institute of Neurological Disorders and Stroke2023$1,825,919February 15, 2019July 31, 2026PETERSSON, ERNEST JAMESreporter.nih.gov
Proteostasis dysregulation and alpha-synucleinNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,813,410May 1, 2020April 30, 2025QI, XINreporter.nih.gov
Network and cellular vulnerability to pathological protein progressionNIHNational Institute on Aging2022 to 2025$1,808,647May 1, 2022April 30, 2027HENDERSON, MICHAELreporter.nih.gov
Role of APOE in endosomal processing of alpha-synucleinNIHNational Institute on Aging2023 to 2024$1,757,895September 1, 2023August 31, 2025DAVIS, ALBERT Areporter.nih.gov
Novel Systemic Delivery of Peptide-Mediated Anti-Sense Oligonucleotides for Dementia with Lewy BodiesNIHNational Institute on Aging2021$1,751,085May 15, 2021April 30, 2024RISSMAN, ROBERTreporter.nih.gov
Fluorescent IRE sensor for synucleinopathy drug discoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,728,231September 22, 2022August 31, 2025SHEN, WENreporter.nih.gov
Synergistic Enhancement of ER proteostasis, trafficking, and lysosomes as treatments for Dementia with Lewy bodies and Parkinson’s disease-dementiaNIHNational Institute of Neurological Disorders and Stroke2024$1,707,089August 15, 2024July 31, 2027MAZZULLI, JOSEPH Rreporter.nih.gov
Combinatorial effects of PTMs on a-Synuclein structure, function and aggregationNIHNational Institute of Neurological Disorders and Stroke2022$1,706,062April 15, 2022March 31, 2025RHOADES, ELIZABETHreporter.nih.gov
Molecular Mechanisms of Oxidation Resistance 1 in Parkinson's disease and Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,704,192August 1, 2023May 31, 2028THOMAS, BOBBYreporter.nih.gov
Developing an Individualized Deep Connectome Framework for ADRD AnalysisNIHNational Institute of Neurological Disorders and Stroke2022$1,686,621August 18, 2022May 31, 2025ZHU, DAJIANGreporter.nih.gov
Cortical Alpha-Synuclein in DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,683,467February 15, 2023January 31, 2028ALDRIDGE, GEORGINAreporter.nih.gov
Reciprocal interactions between cortical circuit dysfunction and α-synuclein pathologyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,674,295February 1, 2023January 31, 2028ZEIGER, WILLIAM ABELreporter.nih.gov
Cholinergic Mechanisms in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,653,870April 1, 2023March 31, 2028MOEHLE, MARK Sreporter.nih.gov
The cross-talk between a-Synucleinopathies and T cell immunity in ADRDNIHNational Institute on Aging2024 to 2025$1,621,812August 15, 2024April 30, 2030MAO, XIAOBOreporter.nih.gov
MIF Nuclease actions in Synuclein DementiasNIHNational Institute on Aging2024 to 2025$1,620,473December 1, 2023November 30, 2028DAWSON, VALINA L.reporter.nih.gov
STRUCTURAL BIOLOGY OF ALPHA-SYNUCLEIN IN LEWY BODY DEMENTIANIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,611,362September 30, 2018August 31, 2023KOTZBAUER, PAUL Treporter.nih.gov
Dendrite regulation by the mitochondrial kinase PINK1: Implications for PD/LBDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,596,950September 1, 2017June 30, 2029CHU, CHARLEEN Treporter.nih.gov
CSF Oligomeric α-synuclein targeted nano scavengers as a Parkinson's disease theranosticNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,585,446September 18, 2024June 30, 2029TANIFUM, ERICreporter.nih.gov
Investigations of Dementia in Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2021$1,574,996May 1, 2011August 31, 2023PERLMUTTER, JOEL SYNESreporter.nih.gov
Changes across the lifespan in the use of heuristics to guide decision-makingNIHNational Institute on Aging2022 to 2023$1,573,961May 1, 2019February 28, 2026BASSO, MICHELE Areporter.nih.gov
Genome-wide Prediction of Dementia in Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,554,981September 20, 2019December 31, 2023SCHERZER, CLEMENS Rreporter.nih.gov
Daily Experiences and Well-being among Caregivers for Older Adults Experiencing Lewy Body Dementia.NIHNational Institute on Aging2024 to 2025$1,553,585May 1, 2024February 28, 2029FINGERMAN, KAREN Lreporter.nih.gov
Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM sleep Behavior DisorderNIHNational Institute on Aging2023 to 2024$1,549,576September 1, 2023August 31, 2028HOWELL, MICHAEL Jreporter.nih.gov
Elucidating the Pathomechanisms of APOE4 in Lewy Body DementiaNIHNational Institute on Aging2024 to 2025$1,538,709July 1, 2024March 31, 2029ZHAO, NAreporter.nih.gov
Lewy Body Dementia BiomarkersNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,536,368September 25, 2016November 30, 2023FREY, KIRK A.reporter.nih.gov
NOVEL PET MARKERS OF COGNITIVE IMPAIRMENT IN MANGANESE NEUROTOXICITYNIHNational Institute of Environmental Health Sciences2021 to 2022$1,525,888September 12, 2019May 31, 2024CRISWELL, SUSANreporter.nih.gov
Mechanisms of spreading proteinopathy in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2021$1,512,234September 15, 2021August 31, 2024UNNI, VIVEKreporter.nih.gov
Mapping Synaptic Density in Prodromal and Manifest Lewy Body DementiaNIHNational Institute on Aging2024 to 2025$1,505,046September 25, 2024July 31, 2030GALLAGHER, CATHERINE L.reporter.nih.gov
Mitochondrial Sirtuin 3 in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,499,835June 1, 2019May 31, 2025MCLEAN, PAMELA Jreporter.nih.gov
Genome-Wide Prediction of Dementia in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,487,365September 20, 2019December 31, 2026SCHERZER, CLEMENS Rreporter.nih.gov
Understanding biomarkers of cognitive decline in Lewy body diseasesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,481,568September 19, 2019June 30, 2026CHEN-PLOTKIN, ALICE Sreporter.nih.gov
Molecular and Network Analyses of Lewy Body Dementia PathogenesisNIHNational Institute on Aging2024 to 2025$1,448,065September 5, 2021August 31, 2027CHIN, LIH-SHENreporter.nih.gov
Role of Rab27b in synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2021$1,433,631September 1, 2021August 31, 2024YACOUBIAN, TALENE ALENEreporter.nih.gov
S-Nitrosylation-Dependent Pathological Spread of Abnormal Proteins in Frontotemporal Dementia and Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,431,052August 1, 2021July 31, 2027NAKAMURA, TOMOHIROreporter.nih.gov
Mechanistic Dissection of Lipase (LIPE) Regulation of Fatty Acid Homeostasis as a Parkinson's Disease and Lewy Body Dementia Therapeutic StrategyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,408,421June 1, 2024May 31, 2029FANNING, SARANNAreporter.nih.gov
Pathophysiologic roles of alpha-synuclein at the synapseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,394,015August 15, 2019May 31, 2025ROY, SUBHOJITreporter.nih.gov
The Role of Aberrant Histone Acetylation in the Pathogenesis of Parkinson’s Disease and Related Synucleinopathies.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,366,666July 17, 2024June 30, 2028SOLDNER, FRANKreporter.nih.gov
Effects of 14-3-3θ phosphorylation vesicular transport and alpha-synuclein aggregationNIHNational Institute of Neurological Disorders and Stroke2025$1,361,977June 1, 2025May 31, 2027YACOUBIAN, TALENE ALENEreporter.nih.gov
Synthetic protein mimetics as potential therapeutics for Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,360,513September 19, 2024February 28, 2027KUMAR, SUNILreporter.nih.gov
Biologically Novel Mouse Models of PD with Progressive Synucleinopathy and Early-Onset Tremor and Motor Deficits Responsive to L-DOPANIHNational Institute of Neurological Disorders and Stroke2024$1,344,552May 15, 2019June 30, 2027NUBER, SILKEreporter.nih.gov
Role of altered gut immune response in Lewy Body DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,338,898September 1, 2024June 30, 2029POSTON, KATHLEEN LOMBARDreporter.nih.gov
The Role of GPNMB in Parkinson's Disease.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,312,338August 1, 2024June 30, 2029SOLDNER, FRANKreporter.nih.gov
Phase I Cell Therapy for Maintaining Cholinergic Circuits in the Spectrum of Alzheimer’s DiseaseNIHNational Institute on Aging2024 to 2025$1,310,770June 15, 2024May 31, 2029GERHARDT, GREG A.reporter.nih.gov
Intrinsically disordered domains of α-synuclein: effect of fibril formation and fibril polymorphsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,287,494April 1, 2024March 31, 2029SIEMER, ANSGAR Breporter.nih.gov
Systematic investigation of disease-associated, regulatory variation; illuminating their prediction, molecular consequences and mechanisms contributing to risk of Parkinson disease (PD)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,260,922July 22, 2024June 30, 2029MCCALLION, ANDREW Sreporter.nih.gov
Dementia with Lewy Bodies ConsortiumNIHNational Institute of Neurological Disorders and Stroke2025$1,215,498September 1, 2025August 31, 2028LEVERENZ, JAMES BRUCEreporter.nih.gov
PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for SmallBusiness Innovation Research Grant Applications (Parent SBIR [R43/R44] ClinicalTrial Not AllowedNIHNational Institute of Neurological Disorders and Stroke2021$1,198,087September 30, 2020August 31, 2023LEVINE, TODDreporter.nih.gov
Frontal midline delta/theta rhythms and cognitive control in PDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,156,742September 25, 2017December 31, 2029NARAYANAN, NANDAKUMARreporter.nih.gov
Prevention of complement and immune-mediated Lewy body dementiaNIHNational Institute on Aging2021 to 2022$1,133,146August 15, 2018April 30, 2023ISACSON, OLEreporter.nih.gov
Intersection of GBA and LRRK2 in Lewy Body DementiaNIHNational Institute on Aging2024 to 2025$1,127,274July 15, 2024April 30, 2029LAVOIE, MATTHEW Jreporter.nih.gov
Molecular mechanisms of alpha-synuclein induction and spread of pathobiologyNIHNational Institute of Neurological Disorders and Stroke2023$1,123,395March 1, 2023February 28, 2026GIASSON, BENOIT Ireporter.nih.gov
Mechanisms of Synaptic Dysfunction in Parkinson s and Other Synuclein-Linked DiseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,117,086January 15, 2012May 31, 2027MORGAN, JENNIFER REBECCAreporter.nih.gov
Tau-dependent cognitive deficits in alpha-synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,101,680May 15, 2018February 28, 2025LEE, MICHAEL Kreporter.nih.gov
PROTEOMIC MAPPING OF PATHOLOGICAL INTERACTIONS ACROSS THE SYNUCLEINOPATHY BRAINNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,027,000August 15, 2022November 30, 2025KILLINGER, BRYANreporter.nih.gov
Mechanisms of spreading proteinopathy in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,026,156September 15, 2021August 31, 2027UNNI, VIVEKreporter.nih.gov
Simple, Home-use, neurostimulAtion tReatment for Parkinson's disease dEmeNtia (SHARPEN)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$994,322July 15, 2023April 2, 2025FOSTER, KRISTEN KATHLEENreporter.nih.gov
Towards Generating a Multimodal and Multivariate Classification Model from Imaging and Non-Imaging Measures for Accurate Diagnosis and Monitoring of Dementia in Parkinsons disease.NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$956,383September 1, 2020September 30, 2022MISHRA, VIRENDRA Rreporter.nih.gov
Role of the endolysosomal pathway in Lewy body dementia - from population genomics to single cellsNIHNational Institute on Aging2021$949,468July 1, 2021June 30, 2023BRAS, JOSEreporter.nih.gov
a-Synuclein vulnerability mechanisms and therapeutics in Alzheimer's DiseaseNIHNational Institute on Aging2021$901,300September 1, 2001May 31, 2023RISSMAN, ROBERTreporter.nih.gov
Multi-Stakeholder Engagement for Interdisciplinary Telehealth in Lewy Body DementiaNIHNational Institute on Aging2021 to 2025$857,616September 30, 2021May 31, 2027PATEL, BHAVANAreporter.nih.gov
RNA Targeted Drug Discovery and Development for Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2021$851,067June 1, 2021May 31, 2023MOURADIAN, M. MARALreporter.nih.gov
Slow wave sleep as a biomarker of rehabilitation-induced cognitive improvement in Parkinson's diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$843,021April 1, 2021October 31, 2022AMARA, AMY WILLISreporter.nih.gov
Alpha-Synuclein Induced Network Hyperexcitability in Lewy Body DementiasNIHNational Institute on Aging2021$840,282September 30, 2021August 31, 2023VOSSEL, KEITH ALANreporter.nih.gov
Pathological and cognitive correlations of real time quaking induced conversion in LBD and ADNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$828,489July 15, 2021June 30, 2027COUGHLIN, DAVID Greporter.nih.gov
Changes in synaptic vesicle-binding of alpha-synuclein as an early biomarker for synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2025$793,535December 1, 2024November 30, 2029BURRE, JACQUELINEreporter.nih.gov
The Role of Alzheimer's Disease Genetic Risk in Predicting Parkinson's Disease DementiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$793,430September 15, 2020June 30, 2025TROPEA, THOMAS FRANCISreporter.nih.gov
Neuroplasticity and the emergence of motor and cognitive deficits in prodromal synucleinopathyNIHNational Institute of Neurological Disorders and Stroke2025$787,249August 15, 2022July 31, 2027MACKINNON, COLUM Dreporter.nih.gov
Contribution of transcriptional mutagenesis of oxidative DNA lesions to generatingnew mutant alpha-synuclein species and aggregation toward the pathogenesis of Parkinson'sdiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$785,000May 15, 2018April 30, 2024KIM, YOON-SEONGreporter.nih.gov
The Impact of Beta- and Gamma-Synucleins on Alpha-Synuclein's Synaptic FunctionNIHNational Institute of Neurological Disorders and Stroke2025$783,258April 15, 2022March 31, 2027BURRE, JACQUELINEreporter.nih.gov
Identifying Pathophysiological Signatures of DLB Cognitive and Neuropsychiatric Decline Using a Systems-Based Proteomic ApproachNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$780,624March 1, 2022February 28, 2027HIGGINBOTHAM, LENORAreporter.nih.gov
Imaging Epigenetic Mechanisms in the Lewy Body Dementias with [11C]MartinostatNIHNational Institute on Aging2021$776,355September 30, 2021August 31, 2023GOMPERTS, STEPHEN N.reporter.nih.gov
Cognitive and Affective Network Dysfunction and Neuromodulation in Aging and SynucleinopathyNIHNational Institute on Aging2021 to 2025$772,200May 1, 2021April 30, 2026BURNS, MATTHEW ROBERTreporter.nih.gov
Dissecting the Etiology of The Lewy Body DementiasNIHNational Institute of Neurological Disorders and Stroke2025$764,836May 1, 2022April 30, 2027FINKBEINER, STEVEN Mreporter.nih.gov
Prion and non-prion induction mechanisms of alpha-synuclein pathologyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$759,146September 15, 2018June 30, 2025GIASSON, BENOIT Ireporter.nih.gov
The functional role of MAST1 in mediating a-synucleinopathies and related dementiaNIHNational Cancer Institute2021$749,756February 10, 2020December 31, 2021JIN, LINGTAOreporter.nih.gov
ASC oligomerization and transmission as an initiating event for protein aggregation in Synucleinopathy DementiasNIHNational Institute on Aging2022 to 2024$746,997September 1, 2022August 31, 2025PANICKER, NIKHILreporter.nih.gov
Role of presynaptic targeting of alpha-synuclein in the pathogenesis of Parkinson's Disease and Dementia with Lewy BodiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$742,500May 1, 2018February 28, 2023VOLPICELLI-DALEY, LAURA A.reporter.nih.gov
Higher Order Convolutional Neural Network for Classification of Lewy-body Diseases and Alzheimers DiseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$735,100February 15, 2022January 31, 2027VEMURI, BABA Creporter.nih.gov
Cerebellar cholinergic connections as a biomarker of dementia and gait impairment in Parkinson diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$734,434March 1, 2022February 28, 2027MAITI, BAIJAYANTAreporter.nih.gov
Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2025$732,992June 20, 2025March 31, 2030BARRETT, MATTHEW JAMESreporter.nih.gov
Plasma Cell-Free RNA as Non-invasive Biomarker for NeurodegenerationNIHNational Institute on Aging2022 to 2024$729,126February 1, 2020March 31, 2026IBANEZ, LAURAreporter.nih.gov
Studying Aggregation in Neurodegenerative Disease Using Synthetic ProteinsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$721,970February 15, 2019August 6, 2023PETERSSON, ERNEST JAMESreporter.nih.gov
Changes across the lifespan in the use of heuristics to guide decision-makingNIHNational Institute on Aging2021$711,784May 1, 2019October 15, 2021BASSO, MICHELE Areporter.nih.gov
Higher Order Convolutional Neural Network for Classification of Lewy-body Diseases and Alzheimers DiseaseNIHNational Institute of Neurological Disorders and Stroke2022$702,265February 15, 2022January 31, 2024VEMURI, BABA Creporter.nih.gov
Polo-like-kinase-2-dependent α-Synuclein Serine-129 Phosphorylation: a Physiological RoleDuring Synaptic ActivityNIHNational Institute of Neurological Disorders and Stroke2025$694,072July 15, 2022April 30, 2027DETTMER, ULFreporter.nih.gov
Expanding Mentorship and Neuroimaging Expertise in Patient-Oriented Studies of Brain, Behavior, and Age-Related DementiasNIHNational Institute on Aging2021 to 2024$684,120September 10, 2020April 30, 2026CLAASSEN, DANIEL OLIVERreporter.nih.gov
Theta burst subthalamic nucleus deep brain stimulation for cognitive and motor improvements in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2024$682,922September 18, 2024August 31, 2029LEE, DARRIN JASONreporter.nih.gov
Theta burst subthalamic nucleus deep brain stimulation for cognitive and motor improvements in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2025$678,336September 1, 2025August 31, 2029LEE, DARRIN JASONreporter.nih.gov
α-Synuclein strain properties are associated with diagnosis of and progression to Parkinson's disease with dementiaNIHNational Institute of Neurological Disorders and Stroke2025$673,092March 1, 2022February 28, 2027MAO, XIAOBOreporter.nih.gov
The role of microglia in Parkinson's disease cognitive and motor impairmentNIHNational Institute of Neurological Disorders and Stroke2025$670,600January 1, 2025December 31, 2029MILLS, KELLY ALEXANDERreporter.nih.gov
Midcareer Development Award in Neuroaging and Geriatric Pharmacoepidemiology ResearchNIHNational Institute on Aging2022 to 2025$647,532March 1, 2022February 28, 2027WILLIS, ALLISONreporter.nih.gov
Characterization and targeting of a novel pathway promoting Parkinson’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$647,116August 15, 2023July 31, 2025LAWRENCE, DANIEL Areporter.nih.gov
Examining the role of phosphatidylethanolamine and autophagic disruption in Lewy Body Dementias and Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2021$642,408August 1, 2021January 31, 2024WITT, STEPHAN N.reporter.nih.gov
Dysregulation of Histone Acetylation in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$624,231July 11, 2023June 30, 2025SOLDNER, FRANKreporter.nih.gov
Build-up of beta-amyloid in the brain in Parkinson's diseaseNIHNational Institute of General Medical Sciences2022 to 2025$605,764July 1, 2022December 31, 2026INYUSHIN, MIKHAILreporter.nih.gov
Genome Wide Analysis of Alpha-Synuclein NeurotoxicityNIHNational Institute of Neurological Disorders and Stroke2021$585,729September 25, 2017June 30, 2024FEANY, MEL Breporter.nih.gov
Novel Systemic Delivery of Peptide-Mediated Anti-Sense Oligonucleotides for Dementia with Lewy BodiesNIHNational Institute on Aging2024$578,101May 15, 2021June 1, 2024RISSMAN, ROBERTreporter.nih.gov
Advancing Palliative Care for Older Adults Affected by Neurodegenerative Disease: Parkinsons disease, Alzheimers disease and Related DementiasNIHNational Institute on Aging2021 to 2024$568,772September 15, 2020May 31, 2025KLUGER, BENZI Mreporter.nih.gov
Speech markers of cognitive impairment in Parkinson's diseaseNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$567,618March 4, 2019February 28, 2025SMITH, KARA MICHELLEreporter.nih.gov
A multiplexable in vivo perturbation toolkit to identify genes affecting neurodegeneration in a model of synucleinopathyNIHNational Institute on Aging2023 to 2024$554,302September 30, 2023September 29, 2025PRZEDBORSKI, SERGE Ereporter.nih.gov
Screening for Compounds that Lower Intracellular Alpha-Synuclein LevelsNIHNational Institute on Aging2021 to 2022$553,315May 15, 2021April 30, 2024JOHN, VARGHESEreporter.nih.gov
Developing an Individualized Deep Connectome Framework for ADRD AnalysisNIHNational Institute of Neurological Disorders and Stroke2025$538,572August 18, 2022May 31, 2027ZHU, DAJIANGreporter.nih.gov
Mechanistic Investigation of Neuropathological Interactions between COVID-19 and Progression of Lewy Pathology and DementiaNIHNational Institute of Neurological Disorders and Stroke2024$506,052August 1, 2024July 31, 2025LU, XIAOHONGreporter.nih.gov
Contrasting pathomechanisms of membrane versus cytosol alpha-synuclein excessNIHNational Institute of Neurological Disorders and Stroke2021$504,625April 1, 2021September 30, 2023DETTMER, ULFreporter.nih.gov
Free water imaging in PDNIHNational Institute of Neurological Disorders and Stroke2023$501,220May 1, 2023April 30, 2025POSTON, KATHLEEN LOMBARDreporter.nih.gov
Digital Accessible Remote Olfactory Mediated Health Assessments for Lewy Body DiseaseNIHNational Institute on Aging2025$493,964September 10, 2025July 31, 2027REINEKE, SEANreporter.nih.gov
Genetic and Neuropathologic Underpinnings of Sex Differences in Lewy Body DementiasNIHNational Institute on Aging2024 to 2025$485,710July 1, 2022July 31, 2027BAYRAM, ECEreporter.nih.gov
Novel Systemic Delivery of Peptide-Mediated Anti-Sense Oligonucleotides for Dementia with Lewy BodiesNIHNational Institute on Aging2025$485,466May 15, 2021April 30, 2026RISSMAN, ROBERTreporter.nih.gov
Investigating how the microbiota modulates neuroinflammatory signaling and neurodegeneration in Parkinson's disease and dementiaNIHNational Institute of Neurological Disorders and Stroke2022$482,138September 6, 2022August 31, 2024KORECKA-ROET, JOANNA ALEKSANDRAreporter.nih.gov
NOVEL PET MARKERS OF COGNITIVE IMPAIRMENT IN MANGANESENEUROTOXICITYNIHNational Institute of Environmental Health Sciences2023$475,542September 12, 2019May 31, 2025CRISWELL, SUSANreporter.nih.gov
Functional MRI Biomarkers Predicting Cognitive Progression in PDNIHNational Institute of Neurological Disorders and Stroke2021$473,603August 15, 2017May 31, 2023HANNA-PLADDY, BRENDAreporter.nih.gov
Synaptic vesicle changes in synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2022$464,014July 1, 2022June 30, 2025BURRE, JACQUELINEreporter.nih.gov
Shedding light on functional heterogeneity of dementia-related alpha-synuclein strainsNIHNational Institute on Aging2022$463,124August 15, 2022July 31, 2025LIANG, YAJIEreporter.nih.gov
Role of Rab27b in synucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2024$462,037September 1, 2021August 31, 2025YACOUBIAN, TALENE ALENEreporter.nih.gov
Role of LRP10 in Parkinson's disease and dementia: a knockout mouse modelNIHNational Institute on Aging2025$457,875May 1, 2025April 30, 2027XIONG, YULANreporter.nih.gov
Neurodegeneration and Neuronal Fluctuations in DLB and ADNIHNational Institute on Aging2023 to 2025$456,570July 5, 2023May 31, 2027CHIU, SHANNONreporter.nih.gov
Integrative analysis of proteomics and transcriptomics to delineate vesicular transport related protein abnormalities related to Alzheimer's, Lewy body and mixed PathologiesNIHNational Institute on Aging2022$455,583June 1, 2022May 31, 2025PILLAI, JAGAN AYYAPPANreporter.nih.gov
Chaperone protection in Lewy body and Alzheimer’s dementias: determining the structural, molecular and cellular mechanisms of a novel, non-canonical Hsp70 action blocking a-synuclein oligomerizationNIHNational Institute on Aging2023 to 2024$453,845April 15, 2023March 31, 2026MCCONLOGUE, LISA Creporter.nih.gov
Design and characterization of Nanobodies to dementia-related α-synuclein strains in Parkinson’s diseaseNIHNational Institute on Aging2021$453,658June 1, 2021May 31, 2023WANG, WENJINGreporter.nih.gov
Chemical Fingerprints of Cognitive Impairment-related alpha-Synuclein Strains using 3D Small Molecule Microarray and Related Therapeutic ApplicationNIHNational Institute of Neurological Disorders and Stroke2022$450,313February 15, 2022January 31, 2024MAO, XIAOBOreporter.nih.gov
Myelination and Resilience Against Limbic Alpha-SynucleinopathyNIHNational Institute of Neurological Disorders and Stroke2022$447,461September 26, 2022August 31, 2025LEAK, REHANA KHANreporter.nih.gov
Use of machine learning to quantify cognitive function in AD, FTD, and DLBNIHNational Institute on Aging2021 to 2022$443,109August 1, 2021November 30, 2023DICKERSON, BRADFORD Creporter.nih.gov
Defining The Substrates of Acyl Protein Thioesterase-1: Their Role in Modulating Alpha-Synuclein ToxicityNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$441,690July 1, 2024June 30, 2026HO, GARY P. H.reporter.nih.gov
Exploring the differential spreading of distinct pathological conformers of AD/LBD-related proteins by combining mathematical modeling and functional studyNIHNational Institute on Aging2024 to 2025$440,931September 1, 2024June 30, 2026RAJ, ASHISHreporter.nih.gov
Factors Associated with Healthcare Utilization Among Community-Dwelling Adults with Clinical Features of Dementia with Lewy BodiesNIHNational Institute on Aging2021$440,890September 30, 2021August 31, 2024WYMAN-CHICK, KATHRYN Areporter.nih.gov
Non-Contrast-Enhanced MRI for Brain Perfusion Mapping of Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2025$440,126September 17, 2024July 31, 2029ZHU, DANreporter.nih.gov
Multiclass classification under prioritized error control and specific error costs with applications to dementia classificationNIHNational Institute on Aging2021 to 2022$438,473September 1, 2021May 31, 2024FENG, YANGreporter.nih.gov
Impact of actin binding protein Coronin 1C in the pathogenesis of Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$432,850February 15, 2022January 31, 2025SCHUELE, BIRGITTreporter.nih.gov
Role of Transglutaminase 2 in SynucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2021$431,750July 1, 2021December 31, 2023MOURADIAN, M. MARALreporter.nih.gov
Exploring The Brain Enriched E3 Ubiquitin Ligase TRIM9 in Alzheimer's DiseaseNIHNational Institute on Aging2022$427,625May 15, 2022April 30, 2025GUPTON, STEPHANIEreporter.nih.gov
Development and characterization of EEG signature of cognitive fluctuations in Lewy body dementiaNIHNational Institute on Aging2022$426,938June 15, 2022May 31, 2025BARRETT, MATTHEW JAMESreporter.nih.gov
Transcriptomic assessment of pathology in PD with dementia and dementia with Lewy Bodies using iPSC neurons and brain tissue of the same individualsNIHNational Institute of Neurological Disorders and Stroke2022$423,274August 15, 2022July 31, 2025SATTLER, RITAreporter.nih.gov
Non-Contrast-Enhanced MRI for Brain Perfusion Mapping of Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2024$420,683September 17, 2024July 31, 2029ZHU, DANreporter.nih.gov
Repopulation of the Microglia/Macrophage Niche in Experimental Lewy Body DiseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$420,078September 17, 2024August 31, 2027LEAK, REHANA Kreporter.nih.gov
The Norepinephrine transporter as a therapeutic target for treatment of alpha-synuclein pathology in PDNIHNational Institute of Neurological Disorders and Stroke2021$419,375May 1, 2021December 31, 2023URS, NIKHILreporter.nih.gov
Immunotherapy for Synucleinopathies: Can Gut Microbiota Affect Efficacy?NIHNational Institute of Neurological Disorders and Stroke2023$419,375June 15, 2023May 31, 2026VEDAM-MAI, VINATAreporter.nih.gov
Dnajc13 p.N860S as a physiologic model ofalpha-Synuclein overexpressionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$419,375May 15, 2024April 30, 2027FARRER, MATTHEW Jreporter.nih.gov
Effects of Cognitive Training on Everyday Cognitive and Brain Function in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$418,750July 10, 2023December 31, 2024TINAZ, SULEreporter.nih.gov
PP2A Dysregulation in the Pathogenesis of alpha-SynucleinopathiesNIHNational Institute of Neurological Disorders and Stroke2021$411,687May 1, 2017April 30, 2023MOURADIAN, M. MARALreporter.nih.gov
A new in vivo zebrafish model to study alpha-synuclein aggregation in Lewy Body DiseaseNIHNational Institute of Neurological Disorders and Stroke2023$411,150June 1, 2023May 31, 2026WEISSMAN, TAMILY Areporter.nih.gov
The interactions between myenteric macrophages and enteric neurons shape development and spread of enteric synucleinopathyNIHNational Institute of Neurological Disorders and Stroke2023$408,057July 1, 2023June 30, 2025KHOSHBOUEI, HABIBEHreporter.nih.gov
Optical Sensing of the Spread of Alpha-Synuclein Aggregates in Models of Parkinson's Disease and Related DementiasNIHNational Institute of Neurological Disorders and Stroke2024$406,260July 5, 2024June 30, 2026WEBB, KEVIN Jreporter.nih.gov
Activity-dependent release of human alpha-synucleinNIHNational Institute of Neurological Disorders and Stroke2023$403,010February 1, 2023January 31, 2026LEE, DAEWOOreporter.nih.gov
Mapping Brain Lipid Architecture in Aging, LBD and T Cell Therapy using novel Imaging Mass SpectrometryNIHNational Institute on Aging2024$400,707September 1, 2024August 31, 2026VEDAM-MAI, VINATAreporter.nih.gov
Commercial production of alpha-synuclein fibrils amplified from human postmortem brain tissue to expand the availability of a critical research tool for Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2025$395,951September 19, 2025August 31, 2026KOTZBAUER, PAUL Treporter.nih.gov
Improving End-of-Life Care for Hospitalized Patients with Lewy Body DisordersNIHNational Institute on Aging2024 to 2025$389,880September 3, 2024June 30, 2029AAMODT, WHITLEYreporter.nih.gov
Stabilizing native α-synuclein homeostasis to prevent insoluble α-synuclein aggregatesNIHNational Institute of Neurological Disorders and Stroke2021$386,653August 1, 2017May 31, 2023DETTMER, ULFreporter.nih.gov
Mechanisms of Neurodegeneration in Lewy Body DisordersNIHNational Institute of Neurological Disorders and Stroke2021$385,000July 1, 2017March 31, 2023UNNI, VIVEKreporter.nih.gov
Cortical Mechanisms in Lewy Body DementiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$375,408September 18, 2018June 30, 2023ALDRIDGE, GEORGINAreporter.nih.gov
Cerebrovascular contributions to cognitive impairment in Lewy body dementiasNIHNational Institute on Aging2022 to 2023$362,000February 15, 2022January 31, 2026RYMAN, SEPHIRAreporter.nih.gov
Deep brain stimulation of the Nucleus Basalis of Meynert: the role of stimulation parameters in neurogenesis and cognitive recovery.NIHNational Institute on Aging2022 to 2023$292,000February 1, 2022November 30, 2025KUMBHARE, DEEPAKreporter.nih.gov
Characterizing upstream regulators of glucosylceramide metabolism for Parkinson's disease and Lewy Body DementiaNIHNational Institute on Aging2021 to 2022$291,000January 15, 2021December 31, 2022NORTH, BRIAN J.reporter.nih.gov
Prototype Multimedia ADRD Falls Prevention System for Family CaregiversNIHNational Institute on Aging2021 to 2022$274,754June 1, 2021May 31, 2022PANZER, VICTORIA Preporter.nih.gov
Genetic and Neuropathologic Underpinnings of Sex Differences in Lewy Body DementiasNIHNational Institute on Aging2022 to 2023$250,502July 1, 2022June 30, 2024BAYRAM, ECEreporter.nih.gov
Mechanisms of Endosomal Dysfunction at Synapses in A-Synuclein PathologyNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$248,538July 1, 2023June 30, 2025ROMAN-VENDRELL, CRISTINAreporter.nih.gov
Remote monitoring using commercially available activity trackers and computer vision provides a holistic, low-cost assessment of Parkinson’s disease symptomsNIHNational Institute on Aging2024 to 2025$244,569August 9, 2024April 30, 2029SIMMERING, JACOBreporter.nih.gov
Metals Exposure, Dementia, and Longitudinal Trajectories of Cognition, Functioning, and Neuropsychiatric SymptomsNIHNational Institute on Aging2024 to 2025$240,972August 9, 2024May 31, 2029WANG, XINreporter.nih.gov
Building Capacity to Meet the Palliative Care Needs of People with Parkinson Disease, Lewy Body Dementia and Related Disorders living in Black and Hispanic CommunitiesNIHNational Institute of Neurological Disorders and Stroke2025$231,000March 1, 2025January 31, 2028KLUGER, BENZI Mreporter.nih.gov
Antihypertensives and the Aging BrainNIHNational Institute on Aging2021$227,908August 1, 2019July 31, 2022MARCUM, ZACHARY ADAMreporter.nih.gov
Distinguishing α-Synuclein S129 Phosphorylation in Health and Lewy Body DementiaNIHNational Institute on Aging2024 to 2025$223,751August 15, 2024January 4, 2026RAMALINGAM, NAGENDRANreporter.nih.gov
Competence, Autonomy, Relatedness, and Connections (CARe Connections): A Peer-Led Intervention Designed with Parkinsons Disease & Related Disorders Carepartners to Improve Holistic SupportNIHNational Institute on Aging2024 to 2025$217,186September 1, 2024June 30, 2029SESHADRI, SANDHYAreporter.nih.gov
Metabolo-Genetic Dissection of GBA and Lysosomal Genes in Parkinson's Disease and Lewy Body DementiaNIHNational Institute on Aging2021$200,000August 1, 2020April 30, 2023SHULMAN, JOSHUA Mreporter.nih.gov
Mechanisms for Preserving Neurons in Alzheimer's Disease-Related Dementias Across Drosophila and Mouse ModelsNIHNational Institute on Aging2021$195,625September 30, 2020June 30, 2023FREYBERG, ZACHARYreporter.nih.gov
Mechanism and importance of innate immune activation in a Drosophila GBA mutant model of Parkinson's diseaseNIHNational Institute on Aging2021$194,375September 10, 2020May 31, 2023PALLANCK, LEO Jreporter.nih.gov
Parkinson disease and DBS: cognitive effects in GBA mutation carriersNIHNational Institute of Neurological Disorders and Stroke2021$182,410July 1, 2017May 31, 2023PAL, GIAN Dreporter.nih.gov
Neurodegeneration and Neuronal Fluctuations in DLB and ADNIHNational Institute on Aging2022 to 2023$165,479June 1, 2022July 1, 2023CHIU, SHANNONreporter.nih.gov
ApoE Regulation of Alpha-Synuclein Pathology in Parkinson Disease DementiaNIHNational Institute of Neurological Disorders and Stroke2021$165,255July 1, 2017June 30, 2022DAVIS, ALBERT Areporter.nih.gov
Validation of Small Molecule Enhancers of Mutant Glucocerebrosidase 1 ActivityNIHNational Institute of Neurological Disorders and Stroke2024$163,750July 1, 2024June 30, 2026KO, HANSEOKreporter.nih.gov
Phase 2 Development of a Spoken Language Biomarker of Cognitive Impairment in Parkinson's DiseaseNIHNational Institute on Deafness and Other Communication Disorders2021$158,059May 1, 2019April 30, 2024ROBERTS, ANGELA CHRISTINEreporter.nih.gov
Structural Biology and Biophysics of Alpha-Synuclein Fibrils by Solid-State NMRNIHNational Institute of General Medical Sciences2023 to 2024$143,364April 1, 2023March 31, 2025BORCIK, COLLIN GRIFFINreporter.nih.gov
Role of 14-3-3θ in Environmental Toxicant Exposure and Neuroinflammation in SynucleinopathiesNIHNational Institute of Environmental Health Sciences2023 to 2025$142,016August 1, 2023July 31, 2027STONE, WILLIAM Jreporter.nih.gov
ASC oligomerization and transmission as an initiating event for protein aggregation in Synucleinopathy DementiasNIHNational Institute on Aging2021$135,540May 1, 2020April 30, 2022PANICKER, NIKHILreporter.nih.gov
Investigating the Role of Myenteric Macrophages in Enteric SynucleinopathyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$135,357May 16, 2023March 15, 2026MACKIE, PHILLIPreporter.nih.gov
Influence of Aging on Pathogenic Alpha-Synuclein Strains and Transmission MechanismNIHNational Institute on Aging2021$130,140September 15, 2017February 28, 2022MAO, XIAOBOreporter.nih.gov
Plasma Cell-Free RNA as Non-invasive Biomarker for NeurodegenerationNIHNational Institute on Aging2021$125,096February 1, 2020January 31, 2022IBANEZ, LAURAreporter.nih.gov
Determining the Interacting Effects of GBA, SNCA, and APOE on a-Synuclein Pathology Severity in Dementia with Lewy Bodies and Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$115,628January 1, 2023October 30, 2025GOLDMAN, CAMILLEreporter.nih.gov
Investigating Histone 3 Dopaminylation in Parkinson's DiseaseNIHNational Institute on Aging2024 to 2025$96,752September 9, 2024September 8, 2028CHEN, WINNIEreporter.nih.gov
Causes and Downstream Effects of 14-3-3 Phosphorylation in SynucleinopathiesNIHNational Institute of Environmental Health Sciences2023 to 2025$84,542January 1, 2024December 31, 2027PAIR, FRANK SANDERSreporter.nih.gov
Role of Rab27 Isoforms on Alpha-Synuclein Endocytosis and ClearanceNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$81,311September 25, 2024September 24, 2026SCHOLZ, KASANDRA Jreporter.nih.gov
The role for cell cycle regulators in trichloroethylene induced Parkinson's dementiaNIHNational Institute of Environmental Health Sciences2024 to 2025$81,092August 1, 2024July 31, 2027ADAMSON, ASHLEYreporter.nih.gov
The Proactive and Reactive Neuromechanics of Instability in Aging and Dementia with Lewy BodiesNIHNational Institute on Aging2023 to 2025$80,580January 1, 2024June 30, 2027EICHENLAUB, EMILY KATHRYNreporter.nih.gov
The effect of GBA1 L444P heterozygous mutation on synaptic morphology in the hippocampus and cognition related to Lewy body dementiasNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$76,846July 1, 2022June 30, 2024MAHONEY-CRANE, CASEYreporter.nih.gov
Nigrostriatal dopamine mechanisms of cognitive controlNIHNational Institute of Neurological Disorders and Stroke2023$72,011August 1, 2023July 31, 2024BOVA, ALEXANDRA SHELLYreporter.nih.gov
The role of beta-synuclein in synaptic vesicle releaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$68,545June 15, 2022June 30, 2023KOMER, LAURENreporter.nih.gov
Identifying the genetic basis of variably protease-sensitive prionopathyNIHNational Institute of Neurological Disorders and Stroke2022$66,800February 1, 2022January 31, 2023MINIKEL, ERIC VALLABHreporter.nih.gov
Role of Glucosylsphingosine in Parkinson Disease and Dementia with Lewy BodiesNIHNational Institute of Neurological Disorders and Stroke2022$63,650September 15, 2019May 31, 2024CHANDRA, SREEGANGA Sreporter.nih.gov
Querying the Interactome of Alpha-Synuclein During Pathological ProcessesNIHNational Institute of Neurological Disorders and Stroke2025$49,538August 27, 2025August 26, 2027FERNANDES, ANALIESEreporter.nih.gov
Contribution of the interaction between synuclein and tau in the pathophysiology of dementia with Lewy bodiesNIHNational Institute on Aging2021$46,585September 1, 2018August 31, 2022STOYKA, LINDSAY ELIZABETHreporter.nih.gov
Combining Chemical Biology and Machine Learning to Generate Reproducible Amyloid FibrilsNIHNational Institute on Aging2024$45,304September 5, 2024September 4, 2025PEREZ, RYANN MICHAELreporter.nih.gov
PINK1 regulates cytoplasmic dynein and mitochondrial transportNIHNational Institute of Neurological Disorders and Stroke2021$45,016November 1, 2019October 31, 2021OTERO, PETER ANTHONYreporter.nih.gov
Utilizing microRNA in cerebrospinal fluid to evaluate the effects of tyrosine kinase inhibition via Nilotinib on gene regulation in individuals with Parkinson's disease or Alzheimer's diseaseNIHNational Institute of Neurological Disorders and Stroke2021$29,116July 1, 2020August 21, 2021FOWLER, ALANreporter.nih.gov
Cortical Neuronal Vulnerability in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2025$26,651June 1, 2025September 26, 2025GORALSKI, THOMASreporter.nih.gov
Deep brain stimulation of the Nucleus Basalis of Meynert: the role of stimulation parameters in neurogenesis and cognitive recoveryNIHNational Institute on Aging2022$1February 1, 2022May 15, 2022KUMBHARE, DEEPAKreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Mayo Clinic RochesterRochester, MN3$33.1 million0$0
University of FloridaGainesville, FL19$29.9 million0$0
Cognition Therapeutics, Inc.Pittsburgh, PA1$29.5 million0$0
Washington UniversitySaint Louis, MO13$22.6 million0$0
Eip Pharma, Inc.Boston, MA1$21.1 million0$0
Johns Hopkins UniversityBaltimore, MD14$19.6 million0$0
Brigham and Women's HospitalBoston, MA14$18.1 million0$0
University of Alabama at BirminghamBirmingham, AL15$15.5 million0$0
University of PennsylvaniaPhiladelphia, PA11$14.3 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH5$13.6 million0$0
Stanford UniversityStanford, CA7$12 million0$0
Case Western Reserve UniversityCleveland, OH5$11.9 million0$0
Emory UniversityAtlanta, GA4$9.4 million0$0
University of MinnesotaMinneapolis, MN5$8.1 million0$0
University of Michigan at Ann ArborAnn Arbor, MI6$7.7 million0$0
Rush University Medical CenterChicago, IL3$7.7 million0$0
University of IowaIowa City, IA7$7.6 million0$0
Massachusetts General HospitalBoston, MA4$6.6 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA4$6.5 million0$0
Northwestern University at ChicagoChicago, IL3$6.4 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY4$5.8 million0$0
Scripps Research Institute, theLa Jolla, CA3$5.7 million0$0
University of California, San DiegoLa Jolla, CA6$5.7 million0$0
University of Southern CaliforniaLos Angeles, CA5$5.4 million0$0
Seattle Inst for Biomedical/clinical ResSeattle, WA3$5.3 million0$0
Biosensics, LLCNewton, MA1$5.2 million0$0
University of Wisconsin-MadisonMadison, WI3$4.7 million0$0
University of WashingtonSeattle, WA5$4.5 million0$0
Weill Medical Coll of Cornell UnivNew York, NY5$4.5 million0$0
University of RochesterRochester, NY4$4.5 million0$0
University of California Los AngelesLos Angeles, CA4$3.8 million0$0
Institute for Molecular MedicineHuntington Beach, CA1$3.6 million0$0
CND Life Sciences, Inc.Scottsdale, AZ2$3.6 million0$0
Columbia University Health SciencesNew York, NY2$3.6 million0$0
Marine Biological LaboratoryWoods Hole, MA3$3.5 million0$0
Albert Einstein College of MedicineBronx, NY3$3.3 million0$0
Georgetown UniversityWashington, DC2$3.2 million0$0
Ut Southwestern Medical CenterDallas, TX1$3.2 million0$0
University of Miami School of MedicineCoral Gables, FL1$3.2 million0$0
J. David Gladstone InstitutesSan Francisco, CA2$3.1 million0$0
Brown UniversityProvidence, RI1$3.1 million0$0
Mayo Clinic JacksonvilleJacksonville, FL3$3.1 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX1$3.1 million0$0
Lovelace Biomedical Research InstituteAlbuquerque, NM2$3 million0$0
Amydis Diagnostics, Inc.La Jolla, CA1$3 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ1$3 million0$0
Advanced Brain Monitoring, Inc.Carlsbad, CA1$2.9 million0$0
Oregon Health & Science UniversityPortland, OR3$2.9 million0$0
Neurodex INCArlington, MA1$2.9 million0$0
Hugo W. Moser Res Inst Kennedy KriegerBaltimore, MD2$2.8 million0$0
Van Andel Research InstituteGrand Rapids, MI3$2.8 million0$0
Tufts University BostonBoston, MA1$2.7 million0$0
Colorado State UniversityFort Collins, CO1$2.7 million0$0
Rbhs-Robert Wood Johnson Medical SchoolPiscataway, NJ5$2.7 million0$0
Maphabit, Inc.Atlanta, GA1$2.7 million0$0
University of Colorado DenverAurora, CO2$2.6 million0$0
Banner HealthPhoenix, AZ1$2.3 million0$0
University of Texas at ArlingtonArlington, TX2$2.2 million0$0
Yale UniversityNew Haven, CT3$2 million0$0
University of Georgia Research Foundation IncAthens, GA1$1.9 million0$0
Parabon Nanolabs, Inc.Reston, VA1$1.9 million0$0
Tufts UniversityMedford, MA1$1.8 million0$0
Baylor College of MedicineHouston, TX2$1.8 million0$0
Lucerna, Inc.Brooklyn, NY1$1.7 million0$0
Medical University of South CarolinaCharleston, SC1$1.7 million0$0
University of Texas at AustinAustin, TX1$1.6 million0$0
Louisiana State Univ HSC ShreveportShreveport, LA3$1.4 million0$0
University of DenverDenver, CO1$1.4 million0$0
University of KentuckyLexington, KY1$1.3 million0$0
Virginia Commonwealth UniversityRichmond, VA3$1.2 million0$0
Mclean HospitalBelmont, MA1$1.1 million0$0
Scion Neurostim, LLCDurham, NC1$994,3220$0
University of Maryland BaltimoreBaltimore, MD2$936,7270$0
ST. Joseph's Hospital and Medical CenterPhoenix, AZ2$898,8160$0
University of California, San FranciscoSan Francisco, CA2$894,7760$0
Duquesne UniversityPittsburgh, PA2$867,5390$0
Vanderbilt University Medical CenterNashville, TN1$684,1200$0
Universidad Central del CaribeBayamon, PR1$605,7640$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA1$567,6180$0
Univ of North Carolina Chapel HillChapel Hill, NC2$508,2050$0
Aromha, Inc.Potomac, MD1$493,9640$0
University of Connecticut SCH of Med/dntFarmington, CT1$457,8750$0
Mayo Clinic ArizonaScottsdale, AZ1$456,5700$0
Healthpartners InstituteBloomington, MN1$440,8900$0
New York UniversityNew York, NY1$438,4730$0
Lewis and Clark CollegePortland, OR1$411,1500$0
Purdue UniversityWest Lafayette, IN1$406,2600$0
Ohio UniversityAthens, OH1$403,0100$0
Helical Biosciences LLCSaint Louis, MO1$395,9510$0
Creighton UniversityOmaha, NE1$291,0000$0
Brookside Research & Development CompanyCoupeville, WA1$274,7540$0
Northwestern UniversityChicago, IL1$158,0590$0
Broad Institute, Inc.Cambridge, MA1$66,8000$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025116$96,807,8540$0
2024127$92,072,6700$0
2023118$100,735,6320$0
2022116$95,732,0670$0
2021104$84,369,0330$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 3 awards here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 163 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 163 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 163 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 163 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 163 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 163 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 163 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 163 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 163 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 163 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 163 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 163 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 163 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 163 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 163 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 163 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.853January 27, 2027$500,000Same assistance listing 93.853 as 163 awards here
Translational Neural Devices (R61/R33 - Clinical Trial Optional)PAR-25-053NIH93.853January 28, 2027Not listedSame assistance listing 93.853 as 163 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIH93.853January 28, 2027$750,000Same assistance listing 93.853 as 163 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.