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Intellectual and Developmental Disabilities (IDD): 2,410 NIH awards ($2.9B) to 364 organizations

2,410 NIH awards ($2.9B) in the NIH spending category Intellectual and Developmental Disabilities (IDD), to 364 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 2,410 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)NIHNational Institute on Aging2021 to 2025$82,684,947September 30, 2020August 31, 2026HANDEN, BENJAMIN Lreporter.nih.gov
NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE)NIHNational Heart, Lung, and Blood Institute2023 to 2025$31,474,131September 26, 2025September 25, 2026reporter.nih.gov
The INCLUDE Data Coordinating CenterNIHNational Heart, Lung, and Blood Institute2021 to 2025$27,560,616September 26, 2020August 31, 2030RESNICK, ADAM CAINreporter.nih.gov
A non-viral CRISPR-mediated genome editing delivery platform as a potential therapy for neurogenetic diseasesNIHNational Center for Advancing Translational Sciences2023 to 2025$26,526,303September 20, 2023July 31, 2027JIANG, YONG-HUIreporter.nih.gov
South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)NIHNational Institute of General Medical Sciences2021 to 2025$19,943,827September 30, 2001August 31, 2026GOLDSMITH, EDIE Creporter.nih.gov
State-dependent Decision-making in Brainwide Neural CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$18,155,129August 15, 2021July 31, 2027PANINSKI, LIAM Mreporter.nih.gov
Duke Autism Center of Excellence: A translational digital health and computational approach to early identification, outcome monitoring, and biomarker discovery in autismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$12,545,063September 7, 2017August 31, 2027DAWSON, GERALDINEreporter.nih.gov
Autism Center of Excellence Network: Neurodevelopmental Biomarkers of Late Diagnosis in AutismNIHNational Institute of Mental Health2021 to 2025$12,178,377September 4, 2012June 30, 2027PELPHREY, KEVIN Areporter.nih.gov
A Longitudinal Brain and Behavior Study of Autism From Infancy Through AdolescenceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$11,410,066July 1, 2007August 31, 2027PIVEN, JOSEPHreporter.nih.gov
Supplement to TR01 Human cortical development and neural plasticity altered by trisomy 21NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$11,380,369September 10, 2021August 31, 2027BHATTACHARYYA, ANITAreporter.nih.gov
The INCLUDE Project Down Syndrome Biorepository (DS-Biorepository)NIHNational Institute on Aging2024 to 2025$10,436,444September 30, 2024August 31, 2029ESPINOSA, JOAQUIN M.reporter.nih.gov
Autism Genetics Phase II: Increasing Representation of Human DiversityNIHNational Institute of Mental Health2021 to 2024$9,859,913March 25, 2013May 31, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Prospective Genetic Risk Evaluation and Assessment (PROGRESS) in AutismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$9,460,610September 6, 2022August 31, 2027VEENSTRA-VANDERWEELE, JEREMYreporter.nih.gov
GEARs Combining advances in Genomics and Environmental science to accelerate Actionable Research and practice in ASDNIHNational Institute of Environmental Health Sciences2022 to 2025$9,120,320September 6, 2022August 31, 2027VOLK, HEATHER Ereporter.nih.gov
Multiscale functional characterization of genomic variation in human developmental disordersNIHNational Human Genome Research Institute2021 to 2025$8,736,987September 1, 2021May 31, 2027HON, GARY CHUNGreporter.nih.gov
Public Health and Autism Science advancing Effectual Strategies across the life course (PHASES)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$8,623,178September 6, 2022August 31, 2027ROBINS, DIANA Lreporter.nih.gov
Revisiting ReCHARGE: ECHO Follow up on Middle Childhood and AdolescenceNIHOffice of the Director, National Institutes of Health2021 to 2025$8,577,337September 21, 2016May 31, 2030HERTZ-PICCIOTTO, IRVAreporter.nih.gov
Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep ApneaNIHNational Heart, Lung, and Blood Institute2024 to 2025$8,481,225September 1, 2022August 31, 2027AMIN, RAOUF S.reporter.nih.gov
MRI Based Presymptomatic Prediction of ASDNIHNational Institute of Mental Health2021 to 2024$8,292,562March 16, 2024January 31, 2026PRUETT, JOHN Rreporter.nih.gov
Washington University Intellectual and Developmental Disabilities Research CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$8,281,463July 28, 2020May 31, 2027DOUGHERTY, JOSEPH Dreporter.nih.gov
The Psychiatric Cell Map Initiative: Connecting Genomics, Subcellular Networks, and Higher Order PhenotypesNIHNational Institute of Mental Health2021 to 2022$8,086,271September 5, 2018June 30, 2023KROGAN, NEVAN Jreporter.nih.gov
INCLUDE Down Syndrome Clinical Cohort Coordinating Center (DS-4C)NIHNational Heart, Lung, and Blood Institute2024 to 2025$7,956,250September 20, 2024August 31, 2029HUNTER, JESSICA EZZELLreporter.nih.gov
Institutional Career Development CoreNIHNational Center for Advancing Translational Sciences2021 to 2025$7,493,043June 1, 2017February 28, 2027MCKINNEY, CHRISTY MICHELLEreporter.nih.gov
Predicting and Optimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum DisorderNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$7,366,154September 1, 2019August 31, 2025TAGER-FLUSBERG, HELENreporter.nih.gov
ENVIRONMENTAL INFLUENCES ON NEURODEVELOPMENTAL OUTCOME IN INFANTS BORN VERY PRETERMNIHOffice of the Director, National Institutes of Health2021 to 2022$7,328,850September 21, 2016August 31, 2024LESTER, BARRY M.reporter.nih.gov
Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep ApneaNIHNational Heart, Lung, and Blood Institute2022 to 2023$7,285,275September 1, 2022August 31, 2024AMIN, RAOUF S.reporter.nih.gov
SUPPORT THE ONGOING OPERATIONS OF THE NATIONAL DATABASE FOR AUTISM RESEARCH - NDARNIHNational Institute on Drug Abuse2021$7,242,156January 1, 2021March 31, 2021GOODWIN, JOHNreporter.nih.gov
Autism Genetics Phase II: Increasing Representation of Human DiversityNIHNational Institute of Mental Health2025$7,009,385March 25, 2013May 31, 2028GESCHWIND, DANIEL Hreporter.nih.gov
COBRE in Neurodevelopment and Its DisordersNIHNational Institute of General Medical Sciences2023 to 2025$6,991,499April 1, 2023February 29, 2028COWAN, CHRISTOPHER Wreporter.nih.gov
Toward Healthy Aging in Adults with Autism: A Longitudinal Clinical and Multimodal Brain Imaging StudyNIHNational Institute of Mental Health2022 to 2024$6,900,037September 6, 2022June 30, 2027LAINHART, JANET ELIZABETHreporter.nih.gov
A Longitudinal MRI Study Characterizing Very Early Brain Development in Infants with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$6,871,845September 20, 2018August 31, 2025MARRUS, NATASHAreporter.nih.gov
Clinical trials to prevent Alzheimer's Disease in Down SyndromeNIHNational Institute on Aging2022 to 2024$6,863,895September 15, 2019August 31, 2025RAFII, MICHAEL Sreporter.nih.gov
Early Life Air Pollution Exposures as a Risk Factor for Neurodevelopmental DisordersNIHNational Institute of Environmental Health Sciences2021 to 2025$6,692,816August 1, 2021July 31, 2029CORY-SLECHTA, DEBORAH Areporter.nih.gov
FMRP-mediated Regulation in Human Brain Development and Therapeutic AdvancementNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$6,546,370September 25, 2020June 30, 2025JIN, PENGreporter.nih.gov
Translational medicine and mechanistic studies of brain neurophysiology in Fragile X SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$6,538,717September 25, 2020June 30, 2025ERICKSON, CRAIGreporter.nih.gov
The CHARGE Study Phase II: A Multifactorial Approach to Autism EtiologyNIHNational Institute of Environmental Health Sciences2021 to 2025$6,509,025May 1, 2020January 31, 2027HERTZ-PICCIOTTO, IRVAreporter.nih.gov
University of Rochester Intellectual and Developmental Disabilities Research CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$6,258,574September 6, 2025May 31, 2026FOXE, JOHN Jreporter.nih.gov
Intellectual and Developmental Disabilities Research CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$6,255,512June 1, 2025May 31, 2026JUUL, SANDRA Ereporter.nih.gov
Clinical Translational Research Center for Neurodevelopmental DisordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$6,184,321June 1, 2025May 31, 2026DICHTER, GABRIEL Sreporter.nih.gov
Prenatal Exposures and Child Health Outcomes: A Statewide StudyNIHOffice of the Director, National Institutes of Health2021 to 2023$6,156,799September 21, 2016August 31, 2023KERVER, JEAN MARIEreporter.nih.gov
Data Resource and Administrative Coordination Center for the Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes ConsortiumNIHNational Institute of Mental Health2023 to 2025$5,582,269May 9, 2023April 30, 2028HAUSSLER, DAVID Hreporter.nih.gov
1/3 Effectiveness Trial of the Early Social Interaction (ESI) Model using Mobile Technology for Toddlers with Autism Identified from Early Screening in Primary CareNIHNational Institute of Mental Health2021 to 2023$5,543,163July 16, 2021December 31, 2025WETHERBY, AMY Mreporter.nih.gov
Translational Control in Memory and Brain DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,426,946May 1, 2021April 30, 2029KLANN, ERICreporter.nih.gov
Trajectories and Environments in Autism: a Multi-cohort Study (TEAMS) following autism families in ECHO Phase 2NIHOffice of the Director, National Institutes of Health2021 to 2025$5,407,578September 21, 2016May 31, 2030LYALL, KRISTENreporter.nih.gov
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,391,456June 1, 2019May 31, 2027JAFFREY, SAMIE Rreporter.nih.gov
Assay and Data Generation Center (ADGC) for the Model of iPSC-derived Neurons for NPD (MiNND)NIHNational Institute of Mental Health2023 to 2025$5,271,743May 17, 2023April 30, 2028PANG, ZHIPING P.reporter.nih.gov
Trisomy 21 and its impact on hedgehog-dependent gene regulation and differentiation timingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$5,112,898September 1, 2024March 31, 2026MOSKOWITZ, IVAN PAULreporter.nih.gov
AR² - Autism Replication, Validation, and Reproducibility CenterNIHOffice of the Director, National Institutes of Health2025$5,097,004September 29, 2025September 28, 2028ZHONG, HUA JUDYreporter.nih.gov
Maternal SARS-CoV-2 infection, placenta biology, and neurodevelopmental outcomes in the offspringNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$5,085,297September 5, 2022July 31, 2027URSINI, GIANLUCAreporter.nih.gov
UCLA High-Throughput Neuropsychiatric Disorder Phenotyping Center (UCLA HT-NPC)NIHNational Institute of Mental Health2023 to 2025$5,035,081May 1, 2023April 30, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Identifying the mechanisms of leukemia progressionNIHNational Cancer Institute2021 to 2025$5,032,279September 22, 2021August 31, 2028CRISPINO, JOHN Dreporter.nih.gov
VALIDATE ASD: INDEPENDENT MULTIMODAL REPLICATION AND VALIDATION OF AUTISM DATA-SCIENCE MODELSNIHOffice of the Director, National Institutes of Health2025$4,853,391September 29, 2025September 28, 2028LIU, ZHANDONGreporter.nih.gov
Genetic Determinants of Epilepsy in Murine SystemsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,770,152January 15, 1993July 31, 2026SANDS, TRISTAN Treporter.nih.gov
Multi-site validation of biomarkers and core clinical outcome measures for clinical trial readiness in CDKL5 Deficiency Disorder - SupplementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,693,682February 15, 2021January 31, 2027BENKE, TIMOTHY Areporter.nih.gov
Homeostatic Stabilization of Neural Function in Health and DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,675,400December 1, 2016November 30, 2024DAVIS, GRAEME Wreporter.nih.gov
PET ligand discovery for arginine vasopressinNIHNational Institute of Mental Health2022 to 2025$4,624,148June 10, 2022April 30, 2027LIANG, STEVEN Hreporter.nih.gov
Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDNIHNational Institute of Mental Health2021 to 2024$4,603,597August 6, 2012March 31, 2025FAIR, DAMIEN Areporter.nih.gov
Optimized Affective Computing Measures of Social Processes and Negative Valence in Youth PsychopathologyNIHNational Institute of Mental Health2021 to 2025$4,522,502April 2, 2021January 31, 2027HERRINGTON, JOHN DAVIDreporter.nih.gov
Administrative supplementNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$4,521,282September 1, 2023June 30, 2028FIDLER, DEBORAH Jreporter.nih.gov
Toward Healthy Aging in Adults with Autism: A Longitudinal Clinical and Multimodal Brain Imaging StudyNIHNational Institute of Mental Health2025$4,503,915September 6, 2022June 30, 2027LAINHART, JANET ELIZABETHreporter.nih.gov
JAK Inhibition in Down SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$4,419,892September 25, 2019July 31, 2025ESPINOSA, JOAQUIN M.reporter.nih.gov
Sodium and Calcium Channels: Structure, Function, Neuroplasticity, and DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,413,116May 1, 2019April 30, 2025SCOTT, JOHN Dreporter.nih.gov
NRSA Training CoreNIHNational Center for Advancing Translational Sciences2021 to 2025$4,317,682June 1, 2017February 28, 2027MOORE, MEGANreporter.nih.gov
Genomic and exposomic factors in the cause and rise of autismNIHOffice of the Director, National Institutes of Health2025$4,314,261September 29, 2025September 28, 2028MILLER, JUDITH SUSANNEreporter.nih.gov
From Data to Action: Capturing Meaningful Outcomes in Autism Through Harmonized DataNIHOffice of the Director, National Institutes of Health2025$4,283,587September 29, 2025September 28, 2028KLINGER, LAURA Greporter.nih.gov
Integrated movement tracking for pediatric OPM-MEG studies of intellectual disabilityNIHNational Institute of Mental Health2024 to 2025$4,279,939July 8, 2024August 31, 2026WELSH, JOHN Preporter.nih.gov
Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disordersNIHNational Institute of Environmental Health Sciences2021 to 2025$4,260,150June 1, 2019April 30, 2027ZYLKA, MARK J.reporter.nih.gov
Data science approaches to autism: environmental modulators of the transcriptome and gene-x-environment interactionsNIHOffice of the Director, National Institutes of Health2025$4,255,873September 29, 2025September 28, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Advancing Success & Developmental Outcomes in Autism Spectrum Disorder through Analysis of Secondary Data (ASD3 Outcomes Project)NIHOffice of the Director, National Institutes of Health2025$4,249,998September 29, 2025September 28, 2028ZUCKERMAN, KATHARINE ELIZABETHreporter.nih.gov
Integrating Genetic and Environmental Data to Predict Autism Susceptibility and Heterogeneity in the SPARK CohortNIHOffice of the Director, National Institutes of Health2025$4,249,149September 29, 2025September 28, 2028CHUNG, WENDY Kreporter.nih.gov
Body Composition and Energy Expenditure in Youth with Spina BifidaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$4,224,862July 1, 2019November 30, 2025POLFUSS, MICHELEreporter.nih.gov
Pathogenic Mechanisms in Christianson Syndrome and NHE6-Related DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,197,634September 15, 2019June 30, 2029MORROW, ERIC Mreporter.nih.gov
Neural mechanisms of speech motor control in Autism Spectrum DisordersNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$4,197,540August 2, 2021May 31, 2027DEMOPOULOS, CARLYreporter.nih.gov
Evaluating Assessment and Medication Treatment of ADHD in Children with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$4,182,561May 1, 2024August 31, 2025ESBENSEN, ANNA J.reporter.nih.gov
High-throughput in vivo and in vitro functional and multi-omics screens of neuropsychiatric and neurodevelopmental disorder risk genesNIHNational Institute of Mental Health2023 to 2025$4,152,990May 1, 2023April 30, 2028HOFFMAN, ELLEN Jreporter.nih.gov
STRUCTURAL VARIATION IN NEUROLOGICAL DISEASENIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,141,654December 15, 2017November 30, 2026LUPSKI, JAMES R.reporter.nih.gov
Mechanisms of Synaptic Transmission in Healthy and Disease StatesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,140,156May 1, 2019April 30, 2027KLYACHKO, VITALY Areporter.nih.gov
Functional convergence following disruption of diverse genes associated with neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2025$4,120,229May 20, 2021March 31, 2027BRENNAND, KRISTEN JENNIFERreporter.nih.gov
The Genetic Basis of Vocal LearningNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$4,100,801September 27, 2021August 31, 2026ROBERTS, TODD Freporter.nih.gov
Mapping internal exposome-metabolome dynamics with advanced data science to identify environmental determinants of autism.NIHOffice of the Director, National Institutes of Health2025$3,996,872September 29, 2025September 28, 2028WALKER, DOUGLAS IANreporter.nih.gov
Institutional Career Development CoreNIHNational Center for Advancing Translational Sciences2021 to 2025$3,979,534September 7, 2017June 30, 2027NOLLEN, NICOLE Lreporter.nih.gov
4/4: Improving the Part C Early Intervention Service Delivery System for Children with ASD: A Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2024$3,971,822June 1, 2020April 30, 2025CARTER, ALICE S.reporter.nih.gov
Multimodal investigation of emotional reactivity as a predictor of later psychopathology in infants at risk for ASDNIHNational Institute of Mental Health2021 to 2025$3,956,038July 1, 2021April 30, 2027CHAWARSKA, KATARZYNAreporter.nih.gov
Elucidating the Interplay of Genes and Environment in Autism Using Genomic and Exposure Data from Large PopulationsNIHOffice of the Director, National Institutes of Health2025$3,938,148September 29, 2025September 28, 2027SEBAT, JONATHANreporter.nih.gov
Modeling autism-associated gene-by-environment interactions in human brain organoidsNIHOffice of the Director, National Institutes of Health2025$3,934,201September 29, 2025September 28, 2028STEIN, JASON LOUISreporter.nih.gov
Structure of amyloid fibrils in human neurodegenerative diseases and agingNIHNational Institute of Neurological Disorders and Stroke2023$3,924,261September 30, 2018August 31, 2026VIDAL, RUBENreporter.nih.gov
Laminar dissection of cortical human brain gene expression in neuropsychiatric disordersNIHNational Institute of Mental Health2021 to 2025$3,916,231June 23, 2021September 30, 2026MARTINOWICH, KERIreporter.nih.gov
DS-ARC: A Remote Digital Cognitive Assessment for Down Syndrome-Associated Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2024$3,901,583July 1, 2023March 31, 2028HASSENSTAB, JASON Jreporter.nih.gov
Boston Birth Cohort - Autism Data Science Initiative (BBC-ADSI)NIHOffice of the Director, National Institutes of Health2025$3,861,440September 29, 2025September 28, 2028WANG, XIAOBINreporter.nih.gov
A Family Genetic Study of Autism and Fragile X SyndromeNIHNational Institute of Mental Health2021 to 2025$3,842,448May 1, 2012April 30, 2026LOSH, MOLLY Creporter.nih.gov
Advancing an XIST ASO candidate for the treatment of Rett SyndromeNIHNational Institute of Mental Health2021 to 2025$3,842,186July 1, 2019February 28, 2029LEE, JEANNIE Treporter.nih.gov
Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart DefectsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,824,765July 1, 2015February 28, 2027JENKINS, MICHAEL W.reporter.nih.gov
A Cognitive Test Battery for Intellectual DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,811,118September 22, 2014September 29, 2025HESSL, DAVID Rreporter.nih.gov
NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE)NIHNational Heart, Lung, and Blood Institute2023 to 2025$3,793,717September 23, 2025September 22, 2026reporter.nih.gov
Genomic and functional characterization of ASD and ID-associated MYT1L mutationNIHNational Institute of Mental Health2021 to 2025$3,747,342December 1, 2020October 31, 2026KROLL, KRISTEN Lreporter.nih.gov
Sex-specific trajectories in epigenomic regulation of brain patterningNIHNational Institute of Mental Health2022 to 2025$3,724,234April 15, 2022January 31, 2027VACCARINO, FLORA Mreporter.nih.gov
North Carolina Translational and Clinical Science Institute (NC TraCS) KL2NIHNational Center for Advancing Translational Sciences2021 to 2022$3,722,343March 30, 2018June 30, 2023WEINBERGER, MORRISreporter.nih.gov
Cardiogenesis: Molecular MechanismsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,717,603January 10, 1997May 31, 2028SRIVASTAVA, DEEPAKreporter.nih.gov
Harnessing Clinical Genomic Characterization to Accelerate Translational Advances for Patients with IDDNIHNational Center for Advancing Translational Sciences2021 to 2023$3,682,280May 6, 2020April 30, 2025PAYNE, PHILIP R.O.reporter.nih.gov
Emulating Immune Dysregulation by Trisomy 21 in a Multi-Organ-on-a-Chip SystemNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,649,414September 20, 2021July 31, 2026HAJIPOURAN BENAM, KAMBEZreporter.nih.gov
Neural mechanisms of sensory reactivity and regulation in autism across developmentNIHNational Institute of Mental Health2021 to 2025$3,636,034April 1, 2021January 31, 2027GREEN, SHULAMITE ABRAreporter.nih.gov
Molecular Analysis of Developmental Brain Disorders Associated with Synaptic PathologyNIHNational Institute of Mental Health2021 to 2025$3,625,377June 16, 2017June 30, 2027SODERLING, SCOTT Hreporter.nih.gov
Predicting ASD and Other Developmental Outcomes in the First Year of Life Using EEG in a Diverse Community-Based Sample (Revision)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,611,283December 15, 2021November 30, 2026NELSON, CHARLES ALEXANDERreporter.nih.gov
Manganese exposure and genetic diversity in risk mechanisms for neurodevelopmental disordersNIHNational Institute of Environmental Health Sciences2024 to 2025$3,606,868September 25, 2024July 31, 2029HARRISON, FIONA EDITHreporter.nih.gov
Rare Mutations and Autism Spectrum DisordersNIHNational Institute of Mental Health2021 to 2025$3,601,036August 1, 2013October 31, 2026EICHLER, EVANreporter.nih.gov
SPEECH PERCEPTION AND AUDITORY ABILITIES IN INFANTS, CHILDREN, AND ADULTS WITH DOWN SYNDROMENIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$3,582,608June 1, 2022May 31, 2027LEIBOLD, LORI J.reporter.nih.gov
A Prospective-Longitudinal Investigation of the Biopsychosocial Predictors of Loneliness Across Adolescence in Autism and Typical DevelopmentNIHNational Institute of Mental Health2021 to 2025$3,567,998December 15, 2020November 30, 2026REDCAY, ELIZABETHreporter.nih.gov
Variation in early motor function in autism, cerebellar injury and normal twinsNIHNational Institute of Mental Health2021 to 2025$3,551,413May 1, 2021February 28, 2027MARRUS, NATASHAreporter.nih.gov
Precision Therapy for Neonatal Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,537,721December 1, 2016November 30, 2024FERRIERO, DONNA M.reporter.nih.gov
Addressing disparities in ASD diagnosis using a direct-to-home telemedicine tool: Evaluation of diagnostic accuracy, psychometric properties, and family engagementNIHNational Institute of Mental Health2021 to 2025$3,527,669August 4, 2021July 31, 2027WARREN, ZACHARY Ereporter.nih.gov
Evaluation of Clinical Outcome Assessment (COA) and Potential Biomarkers to Facilitate Interventional Trial for Mucopolysaccharidosis IIID PatientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,519,934September 21, 2021August 31, 2025SINGAMSETTY, SRIKANTHreporter.nih.gov
Longitudinal neuroprotectiveeffects of periconceptional folic acid supplements in help-seeking youth with psychiatric symptomsand healthy controlsNIHNational Institute of Mental Health2021 to 2024$3,513,898August 1, 2020May 31, 2026ROFFMAN, JOSHUA LAWRENCEreporter.nih.gov
The Autistic Brain Over 45: The Anatomic, Functional, and Cognitive PhenotypeNIHNational Institute of Mental Health2021 to 2025$3,506,706May 8, 2015April 30, 2027CARPER, RUTHreporter.nih.gov
Unraveling gut-microbiome-brain interactions in neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2025$3,503,497September 16, 2021June 30, 2027SAHIN, ERGUNreporter.nih.gov
Cross Scale Interrogation of NPD Genes (SING) in miceNIHNational Institute of Mental Health2025$3,498,931January 15, 2025November 30, 2029KIM, YONGSOOreporter.nih.gov
Craniofacial Morphogenesis in Prenatal Alcohol ExposureNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,497,846July 1, 1996August 31, 2029SMITH, SUSAN M.reporter.nih.gov
1/2-Testing the impact of early screening on the long-term outcomes of children with ASDNIHNational Institute of Mental Health2021 to 2023$3,475,118March 5, 2020June 30, 2024PIERCE, KAREN Lreporter.nih.gov
Viral Gene Therapy for Menkes DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,444,962September 1, 2023June 30, 2027KALER, STEPHEN GERARDreporter.nih.gov
Investigating the synaptic pathology of AutismNIHNational Institute of Mental Health2021 to 2025$3,440,128December 1, 2017November 30, 2027SMITH, STEPHEN EDWARD PAUCHAreporter.nih.gov
Developmental methylomics of autism spectrum disorderNIHNational Institute of Mental Health2021 to 2025$3,431,236April 1, 2021January 31, 2027ABERG, KAROLINA ANNAreporter.nih.gov
Auditory function, cognition, language and brain structure in Down Syndrome- Admin SupplementNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$3,424,585January 15, 2022December 31, 2026LITOVSKY, RUTH Yreporter.nih.gov
Prevalence, onset and progression of substance use in adolescents and young adults with Autism Spectrum DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,400,621February 5, 2021January 31, 2027SPIRITO, ANTHONYreporter.nih.gov
A longitudinal study of brain development in children with autismNIHNational Institute of Mental Health2022 to 2025$3,388,150March 1, 2016April 30, 2025EDGAR, JAMES CHRISTOPHERreporter.nih.gov
Foxp-regulated signaling pathways in brain developmentNIHNational Institute of Mental Health2021 to 2025$3,358,588June 15, 2021April 30, 2026KONOPKA, GENEVIEVEreporter.nih.gov
Sleep, Brain Development, and Behavioral Correlates in a Longitudinal Cohort of Children at Risk for ASDNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,355,572September 1, 2025March 31, 2027ESTES, ANNETTEreporter.nih.gov
Cellular and molecular mechanisms underlying DDX3X syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,350,844January 1, 2021November 30, 2026SILVER, DEBRA L.reporter.nih.gov
Dense Analysis of Cortical Circuit Dysfunction in the MECP2-duplication Syndrome of AutismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,332,806January 1, 2021December 31, 2025SMIRNAKIS, STELIOS MANOLISreporter.nih.gov
Preclinical development of a precision therapy for a monogenic mental health disorderNIHNational Institute of Mental Health2024 to 2025$3,330,990April 16, 2024January 31, 2029MILLER, COURTNEY Areporter.nih.gov
Why do Down Syndrome patients have high risk of Hirschsprung disease?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,330,453September 15, 2022July 31, 2027CHAKRAVARTI, ARAVINDAreporter.nih.gov
Functional consequences of fetal-alcohol-induced brain growth abnormalities identified with in utero MRINIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,326,416May 1, 2021February 28, 2027CUZON CARLSON, VERGINIA CARMELLAreporter.nih.gov
Neurodevelopment in children from families with genetic frontotemporal dementia and Alzheimer’s diseaseNIHNational Institute on Aging2022 to 2025$3,300,813February 15, 2022January 31, 2027LEE, SUZEE EURIEreporter.nih.gov
Neonatal Seizure Registry Developmental Functional EValuation (NSR-DEV)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$3,299,442March 15, 2020February 28, 2026GLASS, HANNAH CRANLEYreporter.nih.gov
Gene editing in the brain with CRISPR-PEGNIHNational Institute of Mental Health2021 to 2025$3,288,527April 1, 2021January 31, 2027LEE, HYE YOUNGreporter.nih.gov
Proteogenetics of Autism Spectrum DisordersNIHNational Institute of Mental Health2021 to 2025$3,288,305August 1, 2013June 30, 2027YATES III, JOHN Rreporter.nih.gov
Type I IFN signaling during lung development in Down SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,274,532September 17, 2021June 30, 2027DANOPOULOS, SOULA ATHANASIAreporter.nih.gov
Charting Sex-Specific Developmental Trajectories in Autistic Children: A Multimodal, Accelerated Longitudinal DesignNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,250,459September 14, 2021August 31, 2027HARROP, CLARE ELIZABETHreporter.nih.gov
How Single-Word and Telegraphic Simplification Affects Language Processing and Word Learning in Young Children with Autism Spectrum DisorderNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$3,250,306June 1, 2022May 31, 2027VENKER, COURTNEY Ereporter.nih.gov
Novel computational strategies to deconvolute co-occurring conditions in Down syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$3,246,817September 9, 2022August 31, 2027COSTELLO, JAMES CHRISTOPHERreporter.nih.gov
High-throughput modeling of autism risk genes using zebrafishNIHNational Institute of Mental Health2021 to 2024$3,214,379September 15, 2020April 23, 2025PROBER, DAVID AARONreporter.nih.gov
Designing a Hybrid Intervention Strategy to Reduce Alcohol Exposed Pregnancies.NIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$3,213,267September 5, 2022April 30, 2027DICLEMENTE, RALPH Jreporter.nih.gov
Modeling and manipulating social percepts in individualsNIHNational Institute of Mental Health2022 to 2025$3,203,479May 17, 2022March 31, 2026FINN, EMILY SUZANNEreporter.nih.gov
ACC: Callosal Agenesis as a Window into Common Neurodevelopmental DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,202,009March 1, 2008April 30, 2027ARGILLI, EMANUELAreporter.nih.gov
Brain and Behavioral Development in Autism Spectrum DisorderNIHNational Institute of Mental Health2022 to 2025$3,200,757August 5, 2022May 31, 2027AMARAL, DAVID Greporter.nih.gov
Gene Dosage Imbalance in Neurodevelopmental DisordersNIHNational Institute of Mental Health2022 to 2025$3,189,018March 15, 2005December 31, 2026MARTIN, CHRISTA LESEreporter.nih.gov
A Mobile Game for Domain Adaptation and Deep Learning in Autism HealthcareNIHNational Library of Medicine2021 to 2025$3,183,539July 2, 2021March 31, 2026WALL, DENNIS PAULreporter.nih.gov
Prenatal Environment And Child Health (PEACH) in ECHONIHOffice of the Director, National Institutes of Health2023 to 2024$3,172,491September 1, 2023May 31, 2025SCHMIDT, REBECCA JEANreporter.nih.gov
Transforming Hospitalizations of Autistic Adolescents via a Novel ABA Telehealth PlatformNIHNational Institute of Mental Health2023 to 2025$3,170,320September 30, 2024July 31, 2025OBERLEITNER, RONALDreporter.nih.gov
Early Cognitive Decline in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,165,808July 15, 2020June 30, 2026CONNERS, FRANCES Areporter.nih.gov
Mechanistic and functional dissection of inflammaging in Down syndromeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,165,277September 1, 2022August 31, 2027KHOR, BERNARDreporter.nih.gov
The Development of CategorizationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,161,772August 1, 2014June 30, 2027SLOUTSKY, VLADIMIR Mreporter.nih.gov
An investigation of transdiagnostic mechanisms underlying ASD and ADHD traits among infants at riskNIHNational Institute of Mental Health2021 to 2024$3,158,229July 1, 2020April 30, 2026MILLER, MEGHAN RHYSreporter.nih.gov
Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and AutismNIHNational Institute of Mental Health2022 to 2025$3,142,634March 5, 2022December 31, 2026MUOTRI, ALYSSON R.reporter.nih.gov
Data-driven solutions for temporal, spatial, and spatiotemporal dynamic functional connectivityNIHNational Institute of Mental Health2021 to 2025$3,142,490March 19, 2021January 31, 2027CALHOUN, VINCE Dreporter.nih.gov
The role of the clustered protocadherins in neural circuit formation and implications for neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2025$3,124,493January 15, 2016June 30, 2026MANIATIS, THOMAS Preporter.nih.gov
Rare genetic disorders in NeuroDev: Insight into the genetic and phenotypic heterogeneity of ID, ASD and ADHD in South African PopulationsNIHNational Institute of Mental Health2021 to 2023$3,122,113June 1, 2019March 31, 2025ROBINSON, ELISE Breporter.nih.gov
ASH1L mediated transcription networks in autism spectrum disordersNIHNational Institute of Mental Health2023 to 2025$3,119,859January 1, 2023December 31, 2026LIZARRAGA, SOFIA BEATRIZreporter.nih.gov
Probing Role of Tetrahydrobiopterin in Cerebral Palsy by Using Transgenic RabbitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,115,975December 15, 2020November 30, 2026TAN, SIDHARTHAreporter.nih.gov
Lifestyle and Alzheimer's Disease In Down SyndromeNIHNational Institute on Aging2021 to 2024$3,112,783September 15, 2020August 31, 2025HARTLEY, SIGAN Lreporter.nih.gov
Cerebrovascular contributions to Alzheimer's disease in adults with Down SyndromeNIHNational Institute on Aging2022$3,079,273September 30, 2022August 31, 2025BRICKMAN, ADAM Mreporter.nih.gov
Neurocomputational mechanisms of proactive social behavior deficits in autism spectrum disorderNIHNational Institute of Mental Health2021 to 2024$3,074,688September 15, 2020June 30, 2025SCHILLER, DANIELAreporter.nih.gov
Role of ASTN2 in Cerebellar Circuit Function and ASD-related BehaviorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,069,597December 15, 2020November 30, 2026HATTEN, MARY ELIZABETHreporter.nih.gov
Neural and developmental trajectories of females with autism spectrum disorderNIHNational Institute of Mental Health2022 to 2025$3,059,045May 1, 2022February 28, 2027NORDAHL, CHRISTINE WUreporter.nih.gov
Goalspace: A Platform for Parent-Assisted Behavioral InterventionsNIHNational Institute of Mental Health2021 to 2024$3,056,720July 1, 2020July 31, 2025JAKOBOVITS, REX Mreporter.nih.gov
Predoctoral Training Program in Signaling and Cellular RegulationNIHNational Institute of General Medical Sciences2021 to 2025$3,053,360July 1, 2021June 30, 2026AHN, NATALIE G.reporter.nih.gov
Intersection of causal neurodevelopmental disorder risk genes, cortical circuit function, and cognitive processing required for behavioral adaptionsNIHNational Institute of Mental Health2022 to 2025$3,049,857September 12, 2012October 31, 2027RUMBAUGH, GAVIN Rreporter.nih.gov
Investigating mechanisms underlying impaired social and spatial cognition in rodent models of Fragile X syndromeNIHNational Institute of Mental Health2022 to 2025$3,047,204August 1, 2022May 31, 2027COLGIN, LAURA Lreporter.nih.gov
Assessing Genomic, Regulatory and Transcriptional Variation at Single Nuclei Resolution in the Brains of Individuals with Autism Spectrum DisorderNIHNational Institute of Mental Health2021 to 2025$3,034,663July 27, 2021May 31, 2027NOWAKOWSKI, TOMASZreporter.nih.gov
Discovery and analysis of brain circuits and cell types affected in autism and schizophreniaNIHNational Institute of Mental Health2021 to 2024$3,026,706September 15, 2020July 31, 2025VITKUP, DENNISreporter.nih.gov
BRITE-Eye: An integrated discovery engine for CNS therapeutic targets driven by high throughput genetic screens, functional readouts in human neurons, and machine learningNIHNational Institute of Mental Health2023 to 2024$2,999,997September 19, 2023August 31, 2025WILLIAMS, LUIS ALBERTOreporter.nih.gov
Clinical Trial Readiness for Children 0-5 years with Congenital Muscular Dystrophy Secondary to LAMA2 MutationsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,998,564September 18, 2023August 31, 2028CONNOLLY, ANNE Mreporter.nih.gov
Development of Gene Replacement Therapy for Sanfilippo Syndrome Type CNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$2,990,505September 19, 2022August 31, 2025SINGAMSETTY, SRIKANTHreporter.nih.gov
Attending to all children: Examining the role of alpha oscillations in attention in young children with and without prenatal alcohol exposure (AsCENd)NIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,986,949September 1, 2022June 30, 2027STEPHEN, JULIA MARIEreporter.nih.gov
Unraveling the Genetic Programs Engaged in ASD Neurons Through Coupled Transcriptomic and Phenotypic ReadoutsNIHNational Institute of Mental Health2022 to 2025$2,986,134August 10, 2022June 30, 2027FARHI, SAMOUILreporter.nih.gov
Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,981,285August 15, 2015July 31, 2026WOZNIAK, JEFFREY ROBERTreporter.nih.gov
A Randomized, Double-Blind, Placebo-controlled Clinical Trial of Choline Supplementation during Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive DevelopmentNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,980,724May 1, 2020April 30, 2026JACOBSON, SANDRA W.reporter.nih.gov
A computer vision toolbox for computational analysis of nonverbal social communicationNIHNational Institute of Mental Health2021 to 2024$2,976,152May 1, 2020February 28, 2026TUNC, BIRKANreporter.nih.gov
A Longitudinal Study of Employment and Educational Instability for Young Adults with Autism Spectrum DisorderNIHNational Institute of Mental Health2021 to 2024$2,967,185July 1, 2020April 30, 2026TAYLOR, JULIE LOUNDSreporter.nih.gov
Effects of Hypoglossal Nerve Stimulation on Cognition & Language in Down SyndromeNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,960,609September 15, 2020August 31, 2026HARTNICK, CHRISTOPHER Jreporter.nih.gov
Understanding and Supporting Reproductive Decisions Among Women with Developmental Disabilities that Affect CognitionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,957,240September 21, 2021August 31, 2027HORNER-JOHNSON, WILLIreporter.nih.gov
Defining disease mechanisms in SLC35A2 epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,951,492July 1, 2020April 30, 2025HEINZEN, ERIN Lreporter.nih.gov
Cognitive Outcome Measures in School Age Children with Down Syndrome (ECODS)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,945,851July 20, 2018June 30, 2029ESBENSEN, ANNA J.reporter.nih.gov
Association of the Fragile X Premutation with Cognitive and Behavioral Skills in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,944,001September 1, 2021August 31, 2027HINTON, VERONICA Jreporter.nih.gov
Cell and Network Disruptions and Associated Pathogenenesis in Tauopathy and Down SyndromeNIHNational Institute on Aging2021 to 2024$2,943,744April 15, 2020March 31, 2026FINKBEINER, STEVEN Mreporter.nih.gov
Neural and behavioral predictors of cognitive development and internalizing problems in adolescents with autism spectrum disorderNIHNational Institute of Mental Health2021 to 2024$2,943,059September 11, 2014April 30, 2026SOLOMON, MARJORIEreporter.nih.gov
Noncoding mutations in neurodevelopmental disordersNIHNational Institute of Mental Health2022 to 2025$2,934,224July 1, 2022April 30, 2027TURNER, TYCHELE NAOMIreporter.nih.gov
The Infant Down Syndrome Brain and Behavior StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,927,457September 20, 2024May 31, 2029MARRUS, NATASHAreporter.nih.gov
Commercialization of Selective Dyrk1a Inhibitors for Down SyndromeNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,924,902September 15, 2022August 31, 2027DUNCKLEY, TRAVISreporter.nih.gov
Genomics of Autism in Latinx AncestriesNIHNational Institute of Mental Health2022 to 2025$2,914,582March 3, 2022January 31, 2027BUXBAUM, JOSEPH D.reporter.nih.gov
Identification of metabolic alterations during cortical development in a human cellular model for 22q11.2 deletion syndromeNIHNational Institute of Mental Health2022 to 2025$2,912,854January 18, 2022October 31, 2026PASCA, ANCA MIRABELAreporter.nih.gov
Basic and Clinical Studies in Reinforcing Positive Behaviors in Intellectual and Developmental DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,910,938February 9, 2018January 31, 2028SHAHAN, TIMOTHY Areporter.nih.gov
Predoctoral Training in Molecular and Cellular BiologyNIHNational Institute of General Medical Sciences2021 to 2025$2,884,438July 1, 2020June 30, 2030PREKERIS, RYTISreporter.nih.gov
Genomic basis of phenotypic variability of complex disordersNIHNational Institute of General Medical Sciences2021 to 2025$2,880,294February 1, 2017May 31, 2027GIRIRAJAN, SANTHOSHreporter.nih.gov
Neuroimmunological insights into brain development and dysfunction: an integrative approach focused on microglial dynamicsNIHNational Institute of Mental Health2022 to 2025$2,880,000September 1, 2022August 31, 2027CHEADLE, LUCAS Mreporter.nih.gov
Elucidating the molecular mechanisms behind human neurodevelopmental disorders using brain organoidsNIHNational Institute of Mental Health2022 to 2025$2,876,812February 16, 2022December 31, 2026NOVITCH, BENNETT Greporter.nih.gov
Pubertal, Psychological and Physiological Development in Females with AutismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,872,440September 1, 2022June 30, 2027CORBETT, BLYTHE ANNEreporter.nih.gov
Centriole assembly and function for centrosome and cilia biologyNIHNational Institute of General Medical Sciences2021 to 2025$2,869,745June 1, 2021March 31, 2026PEARSON, CHAD Greporter.nih.gov
Aging Symptom Trajectories in Mother Carriers of the FMR1 PremutationNIHNational Institute on Aging2022 to 2025$2,847,621July 15, 2022March 31, 2027KLUSEK, JESSICAreporter.nih.gov
Defining the Role of Enteric Nervous System Dysfunction in Gastrointestinal Motor and Sensory Abnormalities in Down SyndromeNIHNational Institute of Neurological Disorders and Stroke2023$2,837,478May 1, 2023April 30, 2026BELKIND-GERSON, JAIMEreporter.nih.gov
DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITYNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,836,728May 1, 2020April 30, 2028ANTON, EVA Sreporter.nih.gov
Examining the Effectiveness of the Early Start Denver Model in Community Programs serving Young Autistic ChildrenNIHNational Institute of Mental Health2023 to 2025$2,834,410August 1, 2023June 30, 2028STAHMER, AUBYN C.reporter.nih.gov
Generation and analysis of new mouse models to determine novel therapeutic targets for Down syndrome-associated cognitive deficitsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,832,381September 13, 2022August 31, 2027YU, EUGENEreporter.nih.gov
Statistical approaches to improving functional connectivity estimates with an application to autismNIHNational Institute of Mental Health2022 to 2025$2,829,830April 1, 2022March 31, 2027RISK, BENJAMIN BREWSTERreporter.nih.gov
The eXtraordinarY Babies Study: Natural History of Health and Neurodevelopment in Infants with Sex Chromosome TrisomyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,817,119September 6, 2017March 31, 2028TARTAGLIA, NICOLE RENEEreporter.nih.gov
Optimizing Outcomes through Sequencing Parent-Mediated Interventions for Young Children with AutismNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,815,428August 1, 2022July 31, 2027ROBERTS, MEGAN Yreporter.nih.gov
Emerging therapeutic candidates for rare maternally inherited mitochondrial diseases with shared etiologiesNIHNational Center for Advancing Translational Sciences2023 to 2025$2,806,464July 1, 2021August 31, 2027CHIARAMELLO, ANNE ELIANEreporter.nih.gov
Cellular and molecular determinants of DDX3X syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,805,768May 1, 2021April 30, 2026DE RUBEIS, SILVIAreporter.nih.gov
Neuronal Adaptation and Plasticity after Chronic DisuseNIHNational Institute of Mental Health2021 to 2024$2,805,294July 16, 2004January 31, 2026TSIEN, RICHARD Wreporter.nih.gov
Behavior Measure for Children and Adolescents with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,802,179September 15, 2022August 31, 2027ESBENSEN, ANNA J.reporter.nih.gov
Metabolic Health, Lifestyle, and Risk of Co-Occurring Health Conditions in Down Syndrome (MET-DS)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,800,027September 17, 2024May 31, 2029HARTLEY, SIGAN Lreporter.nih.gov
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in HypotoniaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,798,300September 1, 2021August 31, 2027O'BRIEN, LOUISE M.reporter.nih.gov
Development of mGlu7 receptor allosteric modulators for neurological and psychiatric disordersNIHNational Institute of Mental Health2021 to 2024$2,788,139September 21, 2020June 30, 2026NISWENDER, COLLEEN Mreporter.nih.gov
Molecular mechanism of dysregulated airway antiviral responses in children with Trisomy 21NIHNational Heart, Lung, and Blood Institute2021 to 2025$2,785,088August 15, 2021July 31, 2026NINO, GUSTAVOreporter.nih.gov
Inter-alpha Inhibitors in Hypoxic-Ischemic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023$2,776,920July 1, 2014August 31, 2026LIM, YOW-PINreporter.nih.gov
Understanding the skeleton in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,772,646June 1, 2024May 31, 2027SUVA, LARRY J.reporter.nih.gov
New Down syndrome brain organization revealed by single-cell genomicsNIHNational Institute on Aging2021 to 2022$2,758,286September 15, 2021June 30, 2024CHUN, JEROLDreporter.nih.gov
Prenatal medication exposure in autism, birth complications and developmental disabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,746,129September 13, 2022August 31, 2027REICHENBERG, ABRAHAMreporter.nih.gov
Stratifying the Heterogeneity of Autism Spectrum Disorder: Impact of Co-Occurring Anxiety and ADHDNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,744,825June 11, 2021December 31, 2026CARPENTER, KIMBERLY L Hreporter.nih.gov
Impacts of phthalate exposure on the development of social behavior circuitsNIHNational Institute of Environmental Health Sciences2025$2,737,859September 15, 2025September 14, 2029GRITTON, HOWARDreporter.nih.gov
Autonomic and Sensory Dysfunctions in FMR1 Conditions: Development, Mechanisms and ConsequencesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,731,934July 8, 2022April 30, 2027ROBERTS, JANE Ereporter.nih.gov
New Congenital Disorders of Glycosylation: Therapy and ModelsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,728,508May 1, 2014July 31, 2029FREEZE, HUDSON H.reporter.nih.gov
Using complex video stimuli to elucidate atypical brain functioning in ASDNIHNational Institute of Mental Health2021 to 2025$2,728,242February 1, 2017November 30, 2027KENNEDY, DANIEL PATRICKreporter.nih.gov
Mechanisms of DMP Development and Atrioventricular SeptationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,723,098September 1, 2014August 31, 2027WESSELS, ARNOreporter.nih.gov
Mechanisms of Down syndrome-associated swallowing dysfunction in mouse modelsNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,721,607June 13, 2022May 31, 2027CONNOR, NADINE Preporter.nih.gov
1/4: Improving the Part C Early Intervention Service Delivery System for Children with ASD: A Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2024$2,719,863June 1, 2020May 31, 2026STONE, WENDY L.reporter.nih.gov
Modeling ASD-linked genetic mutations in 3D human brain organoidsNIHNational Institute of Mental Health2021 to 2025$2,714,855February 1, 2018June 30, 2029ARLOTTA, PAOLAreporter.nih.gov
Neurodevelopmental Disorder Risk Gene Regulation of Intrinsic Membrane Excitability: A Rheostat that Tunes Dendritic Morphogenesis to Regulate Circuit Assembly During DevelopmentNIHNational Institute of Mental Health2022 to 2025$2,713,624September 1, 2022June 30, 2027RUMBAUGH, GAVIN Rreporter.nih.gov
Including Adults with Intellectual Disability in Precision Medicine Research - Project ENGAGENIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,709,391July 15, 2022June 30, 2027MCDONALD, KATHERINE ELIZABETHreporter.nih.gov
Down Syndrome: Toward Optimal Trajectories and Health Equity using Medicaid Analytic eXtract (DS -TO-THE-MAX)NIHNational Institute on Aging2021 to 2024$2,708,622September 30, 2021August 31, 2025RUBENSTEIN, ERIC Sreporter.nih.gov
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)NIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,695,257September 16, 2022June 30, 2025WOYNAROSKI, TIFFANYreporter.nih.gov
Human Trisome Project - Latin America NetworkNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,693,143September 20, 2024May 31, 2029ESPINOSA, JOAQUIN M.reporter.nih.gov
Genetic Strategies for Neurodevelopmental ResearchNIHNational Institute of Mental Health2021 to 2025$2,690,098February 15, 2020December 31, 2026AMARAL, DAVID Greporter.nih.gov
Regulation of 22q11 Genes in Embryonic and Adult ForebrainNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,688,826April 1, 2003June 30, 2027LAMANTIA, ANTHONY Sreporter.nih.gov
Test of an Innovative, Scalable Support Program for Parents with a Young Child Recently Diagnosed with Autism Spectrum DisorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,687,005June 17, 2020February 28, 2026FEINBERG, MARK ETHANreporter.nih.gov
Structural characterization of tau conformational heterogeneity in Down syndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,686,309August 1, 2025July 31, 2026SOUTHWORTH, DANIEL RYLANDreporter.nih.gov
Characterizing the spectrum of genomic and phenotypic variation in cerebral palsyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,685,980July 1, 2022June 30, 2027MYERS, SCOTTreporter.nih.gov
Telehealth Parent-Only Treatment for Youth with Autism Spectrum Disorder and Overweight/ObesityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,684,143August 15, 2022June 30, 2027BOUTELLE, KERRI Nreporter.nih.gov
Obesity Prevention Targets for Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,679,116September 3, 2022August 31, 2027DAUNHAUER, LISA ANNreporter.nih.gov
Transcriptional condensates, epigenetic editing and Rett SyndromeNIHNational Institute of Mental Health2021 to 2023$2,677,396September 15, 2014July 31, 2025JAENISCH, RUDOLFreporter.nih.gov
Pathomechanisms of SCN3A-related neurodevelopmental disorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,674,943December 1, 2020November 30, 2026GOLDBERG, ETHAN Mreporter.nih.gov
The relationship between language and executive function in DLD and FXS over timeNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,672,873August 15, 2021May 31, 2027STERLING, AUDRA MARIEreporter.nih.gov
Environmental chemical mixtures and metabolomics in autism spectrum disorderNIHNational Institute of Environmental Health Sciences2021 to 2024$2,667,749January 25, 2020October 31, 2025PETRICK, LAURENreporter.nih.gov
Convergent mechanisms for neurodevelopmental disorder genesNIHNational Institute of Mental Health2021 to 2025$2,665,210May 14, 2021November 30, 2026JENKINS, PAUL MICHAELreporter.nih.gov
Elucidating cutaneous mechanosensory circuits, from development to diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,664,003September 1, 2016August 31, 2024GINTY, DAVID Dreporter.nih.gov
Applied Social Cognitive Skills in the Workplace for Transition-Aged Youth with Autism Spectrum DisorderNIHNational Institute of Mental Health2021 to 2024$2,650,099April 15, 2020March 31, 2026OLSEN, DALE EDWARDreporter.nih.gov
Down Syndrome Early Childhood Omics, Deep Phenotyping, and Epidemiology in Texas: DECODE IT CohortNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,644,869September 17, 2024May 31, 2029LUPO, PHILIPreporter.nih.gov
Transdiagnostic Associations Across Developmental DisordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,639,347September 9, 2022July 31, 2027GRIGORENKO, ELENA Lreporter.nih.gov
3/4: Improving the Part C Early Intervention Service Delivery System for Children with ASD: A Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2024$2,624,121June 1, 2020May 31, 2026WAINER, ALLISON LEIGHreporter.nih.gov
Molecular and Cellular Basis of Neurodevelopmental DisordersNIHNational Institute of Mental Health2021 to 2024$2,619,912March 10, 2020January 31, 2025POWELL, CRAIG Mreporter.nih.gov
Change-Sensitive Assessment of Emotion Dysregulation in ASD Across the LifespanNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,613,156September 10, 2014February 28, 2026MAZEFSKY, CARLA Areporter.nih.gov
Harnessing post-translational regulation of SHANK3 as a boosting strategy for Phelan-McDermid syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,609,540June 1, 2021March 31, 2026HOLDER, JIMMY Lreporter.nih.gov
Neurovascular unit dysfunction in Down syndrome revealed by TBINIHNational Institute of Neurological Disorders and Stroke2022$2,601,812September 7, 2022August 31, 2025HUANG, MINGXIAreporter.nih.gov
REPOSITORY OF MOUSE MODELS FOR CYTOGENETIC RESEARCHNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,600,000September 22, 2020September 21, 2025LUTZ, CATHLEENreporter.nih.gov
Advancing the Lives & HeaLth of Youth and Young Adults with Down Syndrome (ALLY-DS)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$2,598,199September 17, 2024May 31, 2029KELLY, ANDREA BRIDGETreporter.nih.gov
Comparing the Effects of Prenatal Depression and its Treatment on Developmental Outcomes of the OffspringNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,597,768September 25, 2020August 31, 2026AVALOS, LYNDSAY AMMONreporter.nih.gov
Molecular, Cellular and Behavioral Impact of the R203W PACS1 Syndrome MutationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,596,944May 1, 2022March 31, 2027THOMAS, GARYreporter.nih.gov
NeuroDev Kenya: characterizing the epidemiology and etiology of developmental disorders on the Kenyan CoastNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,594,590September 30, 2021August 31, 2026ROBINSON, ELISE Breporter.nih.gov
HIGHLY PARALLEL ANALYSIS OF 5' AND 3' UTR VARIANTS IN NEURODEVELOPMENTAL DISORDERSNIHNational Institute of Mental Health2021 to 2025$2,593,323June 19, 2018January 31, 2029DOUGHERTY, JOSEPH Dreporter.nih.gov
NEUROPHYSIOLOGY OF RESPONDERS AND NON-RESPONDERS WITH CEREBRAL PALSYNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,587,166June 1, 2020May 31, 2026KURZ, MAX Jreporter.nih.gov
Maternal mediators of fetal growth restriction linked to prenatal alcohol exposureNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,579,072September 20, 2022June 30, 2027CHAMBERS, CHRISTINAreporter.nih.gov
Precision Medicine for Inflammatory Treatment for Alzheimer's Disease in Down SyndromeNIHNational Institute on Aging2021 to 2022$2,578,790September 30, 2021August 31, 2024RISSMAN, ROBERTreporter.nih.gov
2/4: Improving the Part C Early Intervention Service Delivery System for Children with ASD: A Randomized Clinical TrialNIHNational Institute of Mental Health2021 to 2024$2,577,224June 1, 2020May 31, 2026INGERSOLL, BROOKEreporter.nih.gov
Sleep Spindle Dynamics as a Clinical Biomarker of Aging, Alzheimer's Disease, and Trisomy 21NIHNational Institute on Aging2023$2,576,936September 15, 2023August 31, 2026PRERAU, MICHAEL Jreporter.nih.gov
Executive Function Outcome Measures for Young Children with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$2,565,709September 13, 2019June 30, 2025FIDLER, DEBORAH Jreporter.nih.gov
Deciphering the Role of the Pumilio1 in Two Distinct Neurological DiseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,563,512June 15, 2019March 31, 2029GENNARINO, VINCENZO ALESSANDROreporter.nih.gov
Neuronal excitability and copy number variation disordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,563,265September 1, 2020May 31, 2026PENZES, PETERreporter.nih.gov
Multimodal Optical Imaging on the Effect of Maternal Polysubstance Exposure on Fetal Brain Microvessel FunctionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,556,302January 1, 2016July 31, 2027LARIN, KIRILL Vreporter.nih.gov
Measuring Health, Function, and Social Well-being in Adults on the Autism SpectrumNIHNational Institute of Mental Health2021 to 2024$2,552,275February 7, 2020November 30, 2025NICOLAIDIS, CHRISTINA Mreporter.nih.gov
Combinatorial function of Foxp1/2/4 in Purkinje cell diversification and cerebellar developmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,552,086April 1, 2021March 31, 2027LI, JAMES Y.Hreporter.nih.gov
Evaluating additive effects of including canines in Regulating Together: A Group Treatment to Address Emotion Dysregulation in youth with autism spectrum disorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,551,933September 1, 2022August 31, 2027SHAFFER, REBECCAreporter.nih.gov
Addressing Structural Disparities in Autism Spectrum Disorder through Analysis of Secondary Data (ASD3)NIHNational Institute of Mental Health2023 to 2025$2,551,790August 1, 2023June 30, 2027ZUCKERMAN, KATHARINE ELIZABETHreporter.nih.gov
A Human iPSC-Based Chimeric Mouse Model of Alzheimers Disease in Down SyndromeNIHNational Institute on Aging2021 to 2024$2,549,299September 30, 2021August 31, 2026JIANG, PENGreporter.nih.gov
Global mapping of altered neural circuits in a mouse model of DDX3X mutationsNIHNational Institute of Mental Health2023 to 2025$2,548,928July 15, 2023April 30, 2026DE RUBEIS, SILVIAreporter.nih.gov
Examining dietary modifiers of associations between air pollution and autism-related outcomes in two cohortsNIHNational Institute of Environmental Health Sciences2021 to 2025$2,548,149August 1, 2021May 31, 2027LYALL, KRISTENreporter.nih.gov
Alcohol and pregnancy: benefits and harms of state-level policiesNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,545,754May 15, 2015February 28, 2027ROBERTS, SARAH C.M.reporter.nih.gov
A hybrid effectiveness-implementation trial of a school based executive function treatment for transition age youth with autismNIHNational Institute of Mental Health2021 to 2024$2,542,924February 1, 2021November 30, 2025KENWORTHY, LAURENreporter.nih.gov
1/2 Cell Type and Region-Specific Regulatory Networks in Human Brain Development and DisordersNIHNational Institute of Mental Health2021 to 2022$2,541,620July 6, 2018March 31, 2024SESTAN, NENADreporter.nih.gov
Cellular and Molecular Analysis of the Psychiatric Risk Gene Transcription Factor 4 (TCF4)NIHNational Institute of Mental Health2021 to 2024$2,540,401September 2, 2016May 31, 2026MAHER, BRADY Jreporter.nih.gov
Digitizing Human Vocal Interaction to Understand and Diagnose AutismNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,534,247June 1, 2020May 31, 2026PARISH-MORRIS, JULIAreporter.nih.gov
Investigating the impacts of COVID-19 school closures on long-term adjustment in youth with or at risk for disabilityNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,531,885July 18, 2022May 31, 2027MCINTYRE, LAURA LEEreporter.nih.gov
Dysregulation of TRIO GEF1 activity in neurodevelopmental disordersNIHNational Institute of Mental Health2023 to 2025$2,527,090September 1, 2023May 31, 2028KOLESKE, ANTHONY Jreporter.nih.gov
Noradrenergic mechanisms in breathing and respiratory pathophysiologiesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,520,373January 15, 2016July 31, 2025RAY, RUSSELL Sreporter.nih.gov
Prenatal Origins of Neurometabolic ConsequencesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,517,422September 1, 2021July 31, 2026DEVASKAR, SHERIN Ureporter.nih.gov
Promoting Prosocial Behavior in Syndromic Intellectual and Developmental DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$2,515,036July 15, 2022June 30, 2026VALLURIPALLI SOORYA, LATHAreporter.nih.gov
Administrative Resource of the CIFASDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,513,767September 30, 2003April 30, 2027RILEY, EDWARD Preporter.nih.gov
Aberrant chromatin regulatory mechanisms in Down syndrome brainNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,510,790September 18, 2024August 31, 2029MAZE, IAN S.reporter.nih.gov
Treatment of Obstructive Sleep Apnea with Personalized Surgery in Children with Down Syndrome (TOPS-DS)NIHNational Heart, Lung, and Blood Institute2022 to 2023$2,502,563September 7, 2022July 31, 2025LAM, DEREK Jreporter.nih.gov
Beyond Gene Dosage: Understanding Down Syndrome via 4D Genome OrganizationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,496,816September 18, 2020August 31, 2025LI, WENBOreporter.nih.gov
Genotype-Phenotype Relationships in Fragile X FamiliesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,496,604June 15, 1998May 31, 2028HAGERMAN, RANDI J.reporter.nih.gov
The Impact of Opioids on Health Outcomes for Hospitalized InfantsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,495,528March 1, 2022February 28, 2027KELLEY-QUON, LORRAINE Ireporter.nih.gov
Fetal cerebral arteries and prenatal alcohol exposureNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,492,106March 15, 2022January 31, 2027BUKIYA, ANNAreporter.nih.gov
MECHANISMS OF EPIGENETIC REGULATION IN NERVOUS SYSTEM DEVELOPMENTNIHNational Institute of Mental Health2021 to 2025$2,491,652March 14, 2019November 30, 2028GABEL, HARRISON Wreporter.nih.gov
Motion Robust Relaxometry for Infant NeuroimagingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,483,302September 20, 2022August 31, 2026ALEXANDER, ANDREW Lreporter.nih.gov
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?NIHNational Institute of Environmental Health Sciences2021 to 2024$2,479,948February 1, 2020November 30, 2025LEHMLER, HANS-JOACHIMreporter.nih.gov
Postnatal Oxytocin Treatment and Cognitive Function in Fragile XNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,479,522April 5, 2021September 30, 2026GALL, CHRISTINE Mreporter.nih.gov
Mechanistic investigation of therapies for Down Syndrome Regression DisorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$2,478,448September 1, 2024August 31, 2027ESPINOSA, JOAQUIN M.reporter.nih.gov
Whole Body Effects of PAE Across the Life Span: Early Markers of & Clinical Interventions for Children and Adolescents in UkraineNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,477,101August 12, 2022April 30, 2027CHAMBERS, CHRISTINAreporter.nih.gov
Parent implemented treatment for repetitive behaviors in children with ASD: Using a novel telehealth approach to increase service accessNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,472,494April 10, 2021March 31, 2027BOYD, BRIAN ANTONIOreporter.nih.gov
Neuroprotection by nNOS inhibitors in perinatal hypoxia-ischemiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,467,775May 1, 2020February 28, 2026TAN, SIDHARTHAreporter.nih.gov
Healthcare Transitions and the Health of Adolescents and Young Adults with Intellectual or Developmental DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,467,524August 10, 2021July 31, 2027CHIEN, ALYNA TUNG-MEIreporter.nih.gov
The Female Songbird as a Novel Mechanistic Model for the Neural Basis of Social EvaluationNIHNational Center for Complementary & Integrative Health2022 to 2025$2,467,500August 15, 2022July 31, 2027GADAGKAR, VIKRAMreporter.nih.gov
Septhohippocamal connectome dysfunction in Down syndrome associated with Alzheimer’s disease pathophysiologyNIHNational Institute on Aging2023$2,466,001February 15, 2023January 31, 2026GINSBERG, STEPHEN Dreporter.nih.gov
The Impact of Pten Signaling on Neuronal Form and FunctionNIHNational Institute of Mental Health2021 to 2024$2,464,895July 15, 2012July 31, 2024LUIKART, BRYAN Wreporter.nih.gov
Development of Translatable Neurophysiological Biomarkers to Accelerate Therapeutic Development in Rett SyndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,464,143April 1, 2023March 31, 2026MARSH, ERIC Dreporter.nih.gov
Systematic and scalable phenotyping of mouse mutants for neuropsychiatric disease geneticsNIHNational Institute of Mental Health2025$2,462,651December 1, 2024November 30, 2029DOUGHERTY, JOSEPH Dreporter.nih.gov
MeCP2 reactivation from the inactive X chromosome as treatment for Rett syndromeNIHNational Institute of Mental Health2023 to 2025$2,456,289September 15, 2023June 30, 2028LIU, X. SHAWNreporter.nih.gov
The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults with Down SyndromeNIHNational Institute on Aging2021 to 2023$2,444,707August 1, 2019April 30, 2025PTOMEY, LAUREN TAYLORreporter.nih.gov
Cerebellum and cerebellar-regulated circuit contribution to Fragile X SyndromeNIHNational Institute of Mental Health2021 to 2024$2,436,836July 1, 2020April 30, 2025TSAI, PETER T.reporter.nih.gov
Development and Validation of Therapy for Mucopolysaccharidosis IIINIHNational Institute of Neurological Disorders and Stroke2022$2,435,870September 1, 2014June 30, 2025WOOD, JILLreporter.nih.gov
A longitudinal study identifying psychological and service delivery targets to improve daily living skills and quality of life outcomes among autistic youth exiting high schoolNIHNational Institute of Mental Health2023 to 2025$2,434,391June 1, 2023March 31, 2028YERYS, BENJAMINreporter.nih.gov
Down Syndrome Connect RegistryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$2,428,283June 15, 2024June 14, 2026ESPINOSA, JOAQUIN M.reporter.nih.gov
Gaining insights: the effects of the RMK gain-of-function mutations on brain development and neurodevelopmental disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,425,503August 21, 2022July 31, 2027GREEN, TAMARreporter.nih.gov
Gene-Environment interactions in AutismNIHNational Institute of Environmental Health Sciences2022 to 2025$2,424,952January 20, 2022November 30, 2026CORCES, VICTOR G.reporter.nih.gov
Attention allocation as a computational mechanism for altered sensory processing in autismNIHNational Institute of Mental Health2023 to 2025$2,420,201August 1, 2023May 31, 2028MURRAY, SCOTT Oreporter.nih.gov
PROMIS-guided development and validation of a dimensional observer-report measure of positive and negative features of ASDNIHNational Institute of Mental Health2021 to 2023$2,417,502August 6, 2019May 31, 2025FOSS-FEIG, JENNIFERreporter.nih.gov
Validating Measures and Unpacking Differences in Service Use for Diverse Children with AutismNIHNational Institute of Mental Health2022 to 2024$2,408,736September 9, 2022May 31, 2027BRODER-FINGERT, SARABETHreporter.nih.gov
Applications of high resolution fMRI in ultra-high field (7T) in revealing developmental disorders underlying amblyopiaNIHNational Eye Institute2021 to 2024$2,407,891April 1, 2020March 31, 2026NASR, SHAHINreporter.nih.gov
A Hybrid Effectiveness-Implementation RCT of Virtual Interview Training for Autistic Transition-Age YouthNIHNational Institute of Mental Health2023 to 2025$2,405,562September 1, 2023May 31, 2027SMITH, MATTHEW JAMESreporter.nih.gov
Molecular and Developmental Analysis of HoloprosencephalyNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,403,316August 1, 2015March 31, 2027KRAUSS, ROBERT S.reporter.nih.gov
Individualized approaches to determining likelihood of ASD casenessNIHNational Institute of Mental Health2022 to 2024$2,402,772July 1, 2022April 30, 2026BISHOP, SOMER L.reporter.nih.gov
PETAL: Promoting Early Intervention Timing and Attention to LanguageNIHNational Institute on Deafness and Other Communication Disorders2023 to 2025$2,398,775June 1, 2023May 31, 2028KASARI, CONNIE L.reporter.nih.gov
Trajectories and Markers of Neurodegeneration in Carriers of the Fragile X PremutationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,395,710June 1, 2007December 31, 2029HESSL, DAVID Rreporter.nih.gov
Dynamic Functional Image-based Deep Learning for Therapy Assessment in AutismNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,395,053June 1, 1996March 31, 2027DUNCAN, JAMES Sreporter.nih.gov
Exploring the role of oxytocin in the regulation of neuronal excitabilityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,392,065May 1, 2021March 31, 2026ESCAYG, ANDREW Preporter.nih.gov
Molecular Mechanisms Underlying the sex-Depended Maturation of Modulatory Systems.NIHNational Institute of Mental Health2022 to 2025$2,392,059September 1, 2022July 31, 2027FUTAI, KENSUKEreporter.nih.gov
IBIS-iPSC: Organoid modeling of cortical surface area hyperexpansion in autism spectrum disorderNIHNational Institute of Mental Health2023 to 2025$2,389,134April 1, 2023January 31, 2028STEIN, JASON LOUISreporter.nih.gov
A Multisite Study of Prenatal Alcohol Exposure: Effects of Inflammation and Endocrine Dysfunction in AdulthoodNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,386,490August 12, 2022April 30, 2027COLES, CLAIRE D.reporter.nih.gov
Social Visual Attention and Language Development in Autism: Leveraging Infant-Directed Speech and Song to Identify Multimodal Mechanisms of CommunicationNIHNational Institute on Deafness and Other Communication Disorders2024$2,383,221September 15, 2024August 31, 2027LENSE, MIRIAMreporter.nih.gov
Improving Transition Outcomes for Youth with Autism through Parent Advocacy Training: A Multi-State Randomized Controlled TrialNIHNational Institute of Mental Health2021 to 2023$2,382,108February 1, 2019November 30, 2025TAYLOR, JULIE LOUNDSreporter.nih.gov
Autism Caregiver Coaching in AfricaNIHNational Institute of Mental Health2022 to 2025$2,369,436August 17, 2022June 30, 2027FRANZ, LAURENreporter.nih.gov
Functional Genetics of the Neuronal Sodium Channel Gene SCN8ANIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,368,240May 1, 1996January 31, 2027MEISLER, MIRIAM Hreporter.nih.gov
Estimating The Fraction of Variance Explained by Genetics and Neuroanatomy in Neuropsychiatric ConditionsNIHNational Institute of Mental Health2022 to 2025$2,366,294August 15, 2022June 30, 2027SCHWARTZMAN, ARMINreporter.nih.gov
Tongue maturation deficits in a mouse model of Down syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,366,038September 22, 2021August 31, 2026GLASS, TIFFANYreporter.nih.gov
Development and Validation of the Down Syndrome Regression Rating ScalesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,364,101September 20, 2023August 31, 2028BROWN, RUTH Creporter.nih.gov
Human Isogenic Organoid Models of Genetic Forms of Autism to Identify Convergent and Divergent Pathomechanisms in AutismNIHNational Institute of Mental Health2023 to 2025$2,362,709August 7, 2023May 31, 2028YEO, EUGENE WEI-MINGreporter.nih.gov
Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder using Transcranial Magnetic StimulationNIHNational Institute of Mental Health2023 to 2025$2,361,288August 1, 2023May 31, 2028ASSAF, MICHALreporter.nih.gov
Understanding neuronal dysfunction in Down Syndrome using assembloids and xenotransplanted cortical organoidsNIHNational Institute on Aging2024$2,357,335September 30, 2024August 31, 2027ZELDICH, ELLAreporter.nih.gov
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's diseaseNIHNational Institute on Aging2021 to 2023$2,346,855April 15, 2019January 31, 2025MOBLEY, WILLIAM Creporter.nih.gov
Novel Approaches to Infant Screening for ASD in Pediatric Primary CareNIHNational Institute of Mental Health2021 to 2023$2,345,504September 15, 2019June 30, 2025DAWSON, GERALDINEreporter.nih.gov
Revisiting ReCHARGE: ECHO Follow up on Middle Childhood and AdolescenceNIHOffice of the Director, National Institutes of Health2023 to 2024$2,341,737September 21, 2016May 31, 2025HERTZ-PICCIOTTO, IRVAreporter.nih.gov
Genetics and Functional Studies of Autosomal Recessive Neurological DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,340,413July 1, 2018June 30, 2029RIAZUDDIN, SAIMAreporter.nih.gov
Investigating Early Social Communication Trajectories of Late Talking Toddlers to Best Predict Language Outcomes for the NIH TALK InitiativeNIHNational Institute of Mental Health2021 to 2023$2,330,320September 18, 2019July 31, 2025WETHERBY, AMY Mreporter.nih.gov
Assessment of Fetal Alcohol Spectrum Disorders (FASD) Using Novel Web-Based ToolsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,329,272September 30, 2003April 30, 2027MATTSON WELLER, SARAH Nreporter.nih.gov
Neurodevelopmental Disorder-Associated Rho Regulators in Neocortical DevelopmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,326,531April 1, 2020January 31, 2026VAN AELST, LINDAreporter.nih.gov
A Randomized Intervention Trial to Increase Access to Reproductive Health Services among Adolescents and Young Adults with intellectual and Developmental DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,326,180February 2, 2023January 31, 2028MCDERMOTT, SUZANNE Wreporter.nih.gov
A molecular investigation of retinoic acid-dependent homeostatic synaptic plasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,319,440May 1, 2020April 30, 2025CHEN, LUreporter.nih.gov
The impact of loss of function DNA sequence variants in the human protocadherin gene cluster on neural circuit assembly.NIHNational Institute of Mental Health2023 to 2025$2,312,266July 1, 2023April 30, 2026MANIATIS, THOMAS Preporter.nih.gov
Unstable nucleus accumbens social representations in models of social behavioral dysfunction.NIHNational Institute of Mental Health2023 to 2025$2,312,210June 15, 2023March 31, 2028GOLSHANI, PEYMANreporter.nih.gov
Identifying pathogenic mechanisms underlying PACS1 Syndrome: implications for neural developmentNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,309,371August 5, 2022July 31, 2027GUEMEZ GAMBOA, ALICIA DIONEreporter.nih.gov
Developing electrophysiological markers for clinical trials in autistic adultsNIHNational Institute of Mental Health2022 to 2024$2,305,930September 5, 2022June 30, 2027ROBERTS, TIMOTHY Preporter.nih.gov
Cellular Mechanisms in Fetal Alcohol Spectrum DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,304,997December 15, 2018May 31, 2029PARNELL, SCOTTreporter.nih.gov
Toward Scalable Biomarker-Based Prediction of ASD in High-Risk InfantsNIHNational Institute of Mental Health2021 to 2023$2,304,711July 16, 2021July 31, 2025JESTE, SHAFALI SPURLINGreporter.nih.gov
Language and Executive Function in Females with ASD or FXSNIHNational Institute on Deafness and Other Communication Disorders2023 to 2025$2,299,215September 1, 2023June 30, 2028STERLING, AUDRA MARIEreporter.nih.gov
Nonsense-mediated mRNA decay and beyondNIHNational Institute of General Medical Sciences2023 to 2025$2,298,136August 1, 2023July 31, 2028MAQUAT, LYNNE Ereporter.nih.gov
High-throughput Functional Analysis of Autism Risk GenesNIHNational Institute of Mental Health2021 to 2025$2,292,590March 1, 2018June 30, 2029HOFFMAN, ELLEN Jreporter.nih.gov
Investigating and targeting apolipoprotein E4 in Down syndrome-associated Alzheimer's diseaseNIHNational Institute on Aging2023$2,282,487July 15, 2023June 30, 2026JOHNSON, NOAH RAYreporter.nih.gov
Suppressing Aneuploidy-associated phenotypes in Down syndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,274,818September 1, 2022August 31, 2027TORRES, EDUARDO MARTINreporter.nih.gov
Neurodevelopmental defects of the thalamocortical pathway as a convergent feature of psychiatric disordersNIHNational Institute of Mental Health2023 to 2025$2,271,274May 1, 2023January 31, 2028NOWAKOWSKI, TOMASZreporter.nih.gov
Change-sensitive Measurement of Adult Functional Outcomes in Developmental DisabilitiesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,270,036May 19, 2020February 28, 2025MAZEFSKY, CARLA Areporter.nih.gov
Mechanism of Gp1 mGluR-dependent translation and plasticityNIHNational Institute of Mental Health2021 to 2025$2,269,230December 1, 2020October 31, 2026TSAI, NIEN-PEIreporter.nih.gov
Metals Dysregulation, Brain Development, and Autism Spectrum DisorderNIHNational Institute of Environmental Health Sciences2021 to 2024$2,266,500March 1, 2020December 31, 2025VOLK, HEATHER Ereporter.nih.gov
In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissuesNIHNational Human Genome Research Institute2023 to 2025$2,265,169March 2, 2023December 31, 2027JIN, XINreporter.nih.gov
Trisomy 21 Model AtlasNIHOffice of the Director, National Institutes of Health2023 to 2025$2,259,564September 19, 2023August 31, 2027GALBRAITH, MATTHEW Dreporter.nih.gov
Down Syndrome: a potential treatment XISTsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,258,071September 1, 2022August 31, 2027SHEEN, VOLNEY Lreporter.nih.gov
Chronic Health Conditions in Survivors of Down Syndrome-Associated LeukemiaNIHNational Cancer Institute2022 to 2025$2,251,638June 20, 2022May 31, 2028GRAMATGES, MARIA MONICAreporter.nih.gov
Community-viable screening for ASD in 9-month-old infants using quantitative eye-tracking assays of social visual engagementNIHNational Institute of Mental Health2021 to 2024$2,250,967September 16, 2019August 31, 2025JONES, WARRENreporter.nih.gov
Neurobiobehavioral markers of stress, saliency, and multisensory dysfunction in autismNIHNational Institute of Mental Health2023 to 2025$2,248,203August 1, 2023May 31, 2028JAO KEEHN, R. JOANNEreporter.nih.gov
Characterization of Branched Chain Amino Acid Metabolism and Its DeficiencyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,234,316July 1, 2016February 28, 2026VOCKLEY, GERARDreporter.nih.gov
Brain and Cognitive Development in the PASS Cohort: The Impact of PrenatalAlcohol ExposureNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,230,991September 15, 2017June 30, 2028SOWELL, ELIZABETH Rreporter.nih.gov
Defining the Chemical Perturbome of Neural Development and ActivityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,227,568September 23, 2022August 31, 2027THYME, SUMMER Breporter.nih.gov
Parsing early emerging heterogeneity related to autism spectrum disorderNIHNational Institute of Mental Health2021 to 2023$2,227,183March 1, 2019December 31, 2024ELISON, JED THOMASreporter.nih.gov
Testing the accuracy of eye tracking as a screening tool for ASD in the general populationNIHNational Institute of Mental Health2023 to 2025$2,226,798May 15, 2023March 31, 2026PIERCE, KAREN Lreporter.nih.gov
A mosaic Down syndrome model system comparing isogenic trisomic/disomic cells to unmask trisomy-21 related genomic, epigenomic, and senescence changes acquired across the lifespanNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$2,217,370May 1, 2023April 30, 2026JACKSON-COOK, COLLEEN Kreporter.nih.gov
Sequence-to-function models for mechanistic investigations of personal genomesNIHNational Human Genome Research Institute2025$2,217,249September 10, 2025August 31, 2029MOSTAFAVI, SARAreporter.nih.gov
Connecting the Dots: An RCT Integrating Standardized ASD Screening, High-Quality Treatment, and Long-Term OutcomesNIHNational Institute of Mental Health2021$2,213,841September 7, 2017November 30, 2023ROBINS, DIANA Lreporter.nih.gov
Cortical and subcortical chandelier cell pathophysiology and symptomatology in autismNIHNational Institute of Mental Health2022 to 2025$2,213,702June 2, 2011November 30, 2026MARTINEZ-CERDENO, VERONICAreporter.nih.gov
Trajectories and Environments in Autism: a Multi-cohort Study (TEAMS) following autism families in ECHO Phase 2NIHOffice of the Director, National Institutes of Health2023 to 2024$2,206,486September 21, 2016May 31, 2025LYALL, KRISTENreporter.nih.gov
Novel therapy for Fragile X syndromeNIHNational Institute of Mental Health2021 to 2022$2,206,174September 15, 2017March 31, 2025TUCCI, FABIO COHENreporter.nih.gov
Postdoctoral Research in Neurodevelopmental DisordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,205,310May 15, 2001April 30, 2027PHILPOT, BENJAMIN Dreporter.nih.gov
Novel video-based approaches for detection of autism risk in the first year of lifeNIHNational Institute of Mental Health2021 to 2023$2,205,038September 9, 2019June 30, 2025OZONOFF, SALLYreporter.nih.gov
Illuminating development of infant and toddler brainfunction with DOTNIHNational Institute of Mental Health2021 to 2024$2,204,631April 1, 2020January 31, 2025EGGEBRECHT, ADAM THOMASreporter.nih.gov
The Impact of hiPSC-Derived Microglia in Human Brain Development in Health and DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,201,423August 1, 2021July 31, 2026MUOTRI, ALYSSON R.reporter.nih.gov
Genomic Insights into the Neurobiology of Cerebral PalsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,200,393April 1, 2019December 31, 2024KRUER, MICHAEL Creporter.nih.gov
A Stage 1 Pilot Test for Feasibility and Efficacy of a Multi-Level Intervention To Increase Physical Activity in Adults with Intellectual Disability: Step it Up +NIHNational Institute on Aging2023 to 2025$2,194,549April 1, 2023January 31, 2028TOMASZEWSKI, BRIANNEreporter.nih.gov
Measuring gene-environment transactions to identify sensitive periods for infant social behavior & brain growthNIHNational Institute of Mental Health2021 to 2024$2,192,884May 2, 2019February 28, 2026JONES, WARRENreporter.nih.gov
Kinase Dysfunction in Autism and Neurodevelopmental DisordersNIHNational Institute of Mental Health2023 to 2025$2,191,861March 15, 2023February 29, 2028YADAV, SMITAreporter.nih.gov
Discovering novel predictors of minimally verbal outcomes in autism through computational modelingNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,183,288August 5, 2022May 31, 2027ROZGA, AGATAreporter.nih.gov
Educational-Clinical Linkage to Improve Health Outcomes for Children with Developmental Delays and DisabilitiesNIHNational Institute of Nursing Research2023 to 2025$2,181,570September 19, 2023June 30, 2028SHAH, RESHMAreporter.nih.gov
Examining adaptive peer-mediated interventions for preschoolers with autism spectrum disorder and limited or no spoken language: A Sequential Multiple Assignment Randomized TrialNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,180,940September 1, 2022May 31, 2027THIEMANN-BOURQUE, KATHYreporter.nih.gov
Spastic paraplegia, neurodegeneration and autism: possible role for AT- 1/SLC33A1?NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,167,309September 20, 2015November 30, 2025PUGLIELLI, LUIGIreporter.nih.gov
The role of immune deregulation and NGF dysmetabolism in the development of Alzheimer disease in individuals with Down syndromeNIHNational Institute on Aging2024 to 2025$2,167,125August 15, 2024July 31, 2029BUSCIGLIO, JORGE Areporter.nih.gov
A mega-analysis framework for delineating autism neurosubtypesNIHNational Institute of Mental Health2023 to 2025$2,161,790April 1, 2023January 31, 2028DI MARTINO, ADRIANAreporter.nih.gov
Non-coding RNA regulation of early neural developmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,159,490December 1, 2019November 30, 2025NISWANDER, LEE A.reporter.nih.gov
Glial chemosensitivity and control of breathing in Rett syndromeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,155,960August 1, 2010December 31, 2025MULKEY, DANIEL Kreporter.nih.gov
Maternal Antecedents and Electronic Fetal Monitoring in Term Asphyxia (MAESTRA)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,155,884May 1, 2020December 31, 2026WU, YVONNE Wreporter.nih.gov
Emergence, stability, and predictors of anxiety in Fragile X syndromeNIHNational Institute of Mental Health2023 to 2025$2,150,560September 1, 2016May 31, 2028HOGAN, ABIGAIL LEEreporter.nih.gov
Role of SCN1B in Inherited EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,149,827February 1, 2011January 31, 2025ISOM, LORI L.reporter.nih.gov
Discovering Eye Tracking Biomarkers of ASD with Diagnostic and Prognostic PowerNIHNational Institute of Mental Health2021 to 2023$2,145,819February 1, 2019November 30, 2023PIERCE, KAREN Lreporter.nih.gov
FX ENTRAIN: Perturbation of neurodynamics underlying sensory hyperarousal and statistical learning in Youth with FXSNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,143,187August 7, 2023July 31, 2028PEDAPATI, ERNEST VIJAYreporter.nih.gov
Mapping the dynamics of mouse neurogenesis in autism models using high-resolution genomic barcoding technologiesNIHNational Human Genome Research Institute2022 to 2025$2,122,481September 16, 2022June 30, 2027KALHOR, REZAreporter.nih.gov
Defining the Role of DNA Rereplication of Chromosome 21 in the Development and Pathophysiology of Down SyndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,113,500January 4, 2021March 31, 2025BLACK, JOSHUA CRANSTONreporter.nih.gov
Investigating monocyte dysfunction in Down SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$2,109,849July 24, 2019December 31, 2024HAMERMAN, JESSICA Areporter.nih.gov
GABAergic Interneuron Dysfunction in Developing Cortical Circuits Underlying Autism Spectrum DisordersNIHNational Institute of Mental Health2021 to 2025$2,109,200December 1, 2020April 30, 2026DE MARCO GARCIA, NATALIA VANESAreporter.nih.gov
Altered Hippocampal Neurogenesis and Cognition via Maneb-mediated Changes in the Thiol Redox Proteome.NIHNational Institute of Environmental Health Sciences2021 to 2023$2,104,664March 1, 2017February 28, 2026ROEDE, JAMES Rreporter.nih.gov
A national birth cohort study of prenatal factors and neurodevelopmental psychiatric disordersNIHNational Institute of Environmental Health Sciences2021 to 2024$2,099,953January 6, 2020October 31, 2025BROWN, ALAN STEWARTreporter.nih.gov
Cerebellar deep brain stimulation for severe combined movement disorders and spasticity in children and young adults with cerebral palsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,095,277April 1, 2024March 31, 2029SAN LUCIANO, MARTAreporter.nih.gov
The role of Myt1l in the developing and adult mouse brainNIHNational Institute of Mental Health2021 to 2023$2,094,570April 1, 2019January 31, 2024WERNIG, MARIUSreporter.nih.gov
IMPACT OF LOSS OF THE AUTISM RISK GENE CHD8 ON EXPRESSION, EPIGENETICS AND CELLULAR FUNCTIONING OF THE DOPAMINERGIC SYSTEMNIHNational Institute of Mental Health2023 to 2025$2,093,618April 17, 2023February 29, 2028MUHLE, REBECCA ANNreporter.nih.gov
Training Program in Neurodevelopmental DisabilitiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,092,347July 1, 1998June 30, 2028EISCH, AMELIA Jreporter.nih.gov
Neural Architecture of Social Emotional Processing and Regulation in Autism Spectrum Disorder: A Dynamic Connectivity PerspectiveNIHNational Institute of Mental Health2021 to 2023$2,089,801April 1, 2019January 31, 2025ASSAF, MICHALreporter.nih.gov
Leveraging Technology to Increase Quality of Life for FASD Across the LifespanNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,089,289July 1, 2017April 30, 2027PETRENKO, CHRISTIE LYNN MCGEEreporter.nih.gov
Alcohol and Developing Neuronal CircuitsNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,086,264April 1, 2005July 31, 2027VALENZUELA, CARLOS FERNANDOreporter.nih.gov
Multimodal dMRI, MRS and MEG studies of language impairment in low-verbal ASDNIHNational Institute on Deafness and Other Communication Disorders2023 to 2025$2,085,943September 1, 2023June 30, 2028ROBERTS, TIMOTHY Preporter.nih.gov
Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,084,787August 16, 2022July 31, 2027GARCIA, BENJAMIN Areporter.nih.gov
Human Epilepsy Genetics - Neuronal Migration DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,084,281July 1, 1997November 30, 2024WALSH, CHRISTOPHER A.reporter.nih.gov
Function of RUNX1 in diverse Down syndrome tissuesNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,081,565September 1, 2023August 31, 2024ALLEN, MARY Areporter.nih.gov
The Role of Autonomic Regulation of Attention in the Emergence of ASDNIHNational Institute of Mental Health2023 to 2025$2,079,560July 1, 2023April 30, 2026BRADSHAW, JESSICAreporter.nih.gov
Prenatal alcohol/cannabinoid co-exposures and fetal brain developmentNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,076,761May 1, 2020April 30, 2026MIRANDA, RAJESH Creporter.nih.gov
Human gene duplications in neurodevelopment and diseaseNIHNational Institute of Mental Health2025$2,075,532September 20, 2023July 31, 2028DENNIS, MEGAN Yreporter.nih.gov
Mechanisms of olfactory signal processingNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,072,411April 1, 2005March 31, 2027SCHOPPA, NATHAN ERICreporter.nih.gov
TSC Proteins in the Lymphatic VasculatureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,069,522July 1, 2023June 30, 2028YANG, YINGreporter.nih.gov
Predicting Autism and Social Functioning from Computer Vision Analyses of Motor Synchrony During Dyadic InteractionsNIHNational Institute of Mental Health2021 to 2023$2,067,909January 1, 2019November 30, 2025SCHULTZ, ROBERT THOMASreporter.nih.gov
Connecting 3D genome misfolding to transcriptional silencing in fragile X syndromeNIHNational Institute of Mental Health2021 to 2024$2,066,257August 15, 2019January 31, 2029PHILLIPS-CREMINS, JENNIFER ELIZABETHreporter.nih.gov
Epigenetic Maintenance of Neural Cell IdentityNIHNational Institute of Mental Health2021 to 2025$2,062,500August 10, 2021May 31, 2026BELL, OLIVERreporter.nih.gov
Leveraging modulation of polyamine metabolism for therapeutic advantage in genetic disordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,060,044February 1, 2023January 31, 2028BACHMANN, ANDRE Sreporter.nih.gov
Positive Airway Pressure For The Treatment Of The Obstructive Sleep Apnea Syndrome In Children With Down SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,055,867September 23, 2019June 30, 2023TAPIA, IGNACIO ESTEBANreporter.nih.gov
Acuity - A Clinical Decision Support System for Applied Behavior AnalysisNIHNational Institute of Mental Health2022 to 2024$2,052,300September 1, 2022August 31, 2025JAKOBOVITS, REX Mreporter.nih.gov
Dynamic RNA Modifications in human brain development and autismNIHNational Institute of Mental Health2021 to 2022$2,051,694August 1, 2018April 30, 2023JIN, PENGreporter.nih.gov
Institutional Career Development CoreNIHNational Center for Advancing Translational Sciences2021 to 2022$2,049,015May 18, 2018June 30, 2023ROBB, SHERI Lreporter.nih.gov
The Impact of Weight Loss on Alzheimer's Disease Risk in Adults with Down SyndromeNIHNational Institute on Aging2024 to 2025$2,048,156September 1, 2022August 31, 2027PTOMEY, LAUREN TAYLORreporter.nih.gov
A Mass Spectrometry Approach to the Genetic and Epigenetic Mechanisms Controlling Neuronal IdentityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,046,607March 1, 2020January 31, 2026DAHMANE, NADIAreporter.nih.gov
Longitudinal mapping of brain-face-behavior trajectories in prenatal alcohol exposure from birth through adolescenceNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,045,919September 20, 2018March 31, 2029JOSHI, SHANTANU H.reporter.nih.gov
Studies on RNA polymerase III-related leukodystrophyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,041,289September 1, 2023August 31, 2028WILLIS, IAN Mreporter.nih.gov
Axonal FMRP in Synaptic DevelopmentNIHNational Institute of Mental Health2021 to 2025$2,040,040September 20, 2021June 30, 2027WANG, YUANreporter.nih.gov
Investigating epigenetic mechanisms in Down syndrome using human cellular modelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$2,034,753April 5, 2023March 31, 2026BARRETT, LINDY ELISEreporter.nih.gov
Harmonization for multisite Connectomics: parsing heterogeneity and creating markers in ASDNIHNational Institute of Mental Health2021 to 2023$2,028,591May 8, 2019January 31, 2025VERMA, RAGINIreporter.nih.gov
Diet and the exposome in autism: Discovering complex interactions with diet in autism etiology and variabilityNIHOffice of the Director, National Institutes of Health2025$2,028,527September 29, 2025September 28, 2027LYALL, KRISTENreporter.nih.gov
ZEBRAFISH MODELS FOR DRAVET SYNDROME RESEARCH AND DISCOVERYNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,025,737April 1, 2016January 31, 2026BARABAN, SCOTT Creporter.nih.gov
A Circuit Mechanism for the Development of Cortico-cortical ConnectivityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,024,140September 30, 2020August 31, 2025DE MARCO GARCIA, NATALIA VANESAreporter.nih.gov
A Family-Genetic Study of Language in AutismNIHNational Institute on Deafness and Other Communication Disorders2023 to 2025$2,022,207September 1, 2023June 30, 2028LOSH, MOLLY Creporter.nih.gov
The function of SCN2A in neocortexNIHNational Institute of Mental Health2021 to 2025$2,018,750April 1, 2021January 31, 2026BENDER, KEVIN Jreporter.nih.gov
Placental identified NHIP regulating neuronal oxidative stress in autismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,013,187August 15, 2023May 31, 2028LASALLE, JANINE Mreporter.nih.gov
Developing an autism-specific mortality risk index using data from Medicare-enrolled autistic older adultsNIHNational Institute on Aging2023 to 2025$2,010,066August 1, 2023April 30, 2028HAND, BRITTANY NICOLEreporter.nih.gov
A Gene-Network Discovery Approach to Structural Brain DisordersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,006,305September 15, 2023May 31, 2028LOUVI, ANGELIKIreporter.nih.gov
Combining Autism Telehealth and Screening Technologies for Earlier Diagnostic AssessmentsNIHNational Institute of Mental Health2021 to 2022$2,005,805August 20, 2015June 30, 2023OBERLEITNER, RONALDreporter.nih.gov
The role of APP in neurogenesis and AD in Down syndromeNIHNational Institute on Aging2022$2,005,131September 15, 2022August 31, 2025LAZAROV, ORLYreporter.nih.gov
AI Mount Sinai: High-performance computational and data ecosystem for biomedical discoveryNIHOffice of the Director, National Institutes of Health2025$1,999,794May 15, 2025May 14, 2026KOVATCH, PATRICIAreporter.nih.gov
Genetic Modifiers of Childhood EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,997,505September 1, 2014December 31, 2025KEARNEY, JENNIFER Areporter.nih.gov
Neuronal and Behavioral Deficits Associated with Scn2a Deficiency in Autism Spectrum DisorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,995,744April 1, 2021March 31, 2027YANG, YANGreporter.nih.gov
Gluconeogenic control of Dravet SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,994,888June 1, 2020May 31, 2026PATEL, MANISHA Nreporter.nih.gov
MOLECULAR PATHOGENESIS STUDIES OF RETT SYNDROMENIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,994,213September 4, 2006April 30, 2026ZOGHBI, HUDA Yreporter.nih.gov
Identification and molecular characterization of somatic mutations in MCDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,992,437September 30, 2016May 31, 2028HEINZEN, ERIN Lreporter.nih.gov
Effects of early life sleep disruption on prefrontal cortex electrophysiological state and affiliation/attachmentNIHNational Institute of Mental Health2025$1,991,026August 1, 2023May 31, 2028WATSON, BRENDON Oreporter.nih.gov
Cortical Interneuron Dysfunction in Fragile X SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,989,137April 1, 2022February 28, 2027PORTERA-CAILLIAU, CARLOSreporter.nih.gov
Testing a computational model of neural responses in autismNIHNational Institute of Mental Health2021 to 2023$1,987,081August 1, 2019May 31, 2025MURRAY, SCOTT Oreporter.nih.gov
Physiological mechanisms of action relating to immediate and long-term therapeutic horseback riding intervention effects in a psychiatric population of youth with autism spectrum disorderNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,986,819January 10, 2020December 31, 2025GABRIELS, ROBIN Lreporter.nih.gov
Effects of Prenatal Alcohol Exposure on Alzheimer's Disease-associated Neuropsychiatric SymptomsNIHNational Institute on Aging2021 to 2024$1,981,250September 30, 2020August 31, 2025MA, YAO-YINGreporter.nih.gov
Mechanisms and pathogenic role of early corticostriatal dysfunction in Shank3B-/- miceNIHNational Institute of Mental Health2021 to 2025$1,977,605December 1, 2020October 31, 2026PEIXOTO, RUIreporter.nih.gov
Tourette Syndrome genetics and neuroimaging international collaborative studyNIHNational Institute of Mental Health2022 to 2025$1,977,219March 4, 2022December 31, 2026PASCHOU, PERISTERAreporter.nih.gov
Prenatal Environment And Child Health (PEACH) in ECHONIHOffice of the Director, National Institutes of Health2025$1,973,808September 1, 2023May 31, 2030SCHMIDT, REBECCA JEANreporter.nih.gov
Sensory Function and Chronic Pain in Cerebral PalsyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,971,719May 14, 2021February 28, 2027SYMONS, FRANK Jreporter.nih.gov
Development of Kv3.1 potentiators for correcting fast-spiking-interneuron hypofunction in schizophrenia and autism spectrum disorderNIHNational Institute of Mental Health2023 to 2025$1,969,171August 1, 2023May 31, 2027DENTON, JEROD S.reporter.nih.gov
Gut-brain dysfunction following combined prenatal stressors: relevance for autismNIHNational Institute of Environmental Health Sciences2021 to 2025$1,969,068April 7, 2021January 31, 2027BILBO, STACI Dreporter.nih.gov
Interneuron axonopathy underlies circuit dysfunction in a mouse model of Dravet syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,968,915April 15, 2019December 31, 2029GOLDBERG, ETHAN Mreporter.nih.gov
Cellular Regulation of Sodium-activated Potassium ChannelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,968,910March 1, 2018November 30, 2027KACZMAREK, LEONARD Kreporter.nih.gov
Understanding the mechanisms of UBE3A regulation in neuronal developmentNIHNational Institute of Mental Health2021 to 2025$1,968,750December 1, 2020November 30, 2026YI, JASON Jreporter.nih.gov
Autism Risk and Maternal Cardiometabolic Health (ARCH) studyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,968,382August 9, 2019May 31, 2025REICHENBERG, ABRAHAMreporter.nih.gov
UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypesNIHNational Institute of Mental Health2021 to 2023$1,967,890September 1, 2019June 30, 2025ZYLKA, MARK J.reporter.nih.gov
Perinatal Experience and Epigenetic Change in Autism: Discovering Modifiable Pathways for InterventionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,967,212August 1, 2023April 30, 2029STRATHEARN, LANEreporter.nih.gov
Rac-GEF signaling in dendritic spinesNIHNational Institute of Mental Health2023 to 2025$1,965,612June 1, 2005April 30, 2026PENZES, PETERreporter.nih.gov
Identification of optimum spectacle prescriptions for patients with Down syndromeNIHNational Eye Institute2021 to 2025$1,964,065September 1, 2014June 30, 2027ANDERSON, HEATHER ANNEreporter.nih.gov
Mechanism of Protein Synthesis and Translational ControlNIHNational Institute of General Medical Sciences2021 to 2025$1,962,066June 1, 2021May 31, 2027JOSEPH, SIMPSONreporter.nih.gov
SIM2 Regulation of Mitochondrial Dysfunction in Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$1,960,246September 13, 2023August 31, 2026PORTER, WESTON Wreporter.nih.gov
Trophoblast progenitor heterogeneity and function in normal and Trisomy 21-affected placentaeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,959,382September 20, 2023June 30, 2028PARAST, MANA Mreporter.nih.gov
A Physiologically Integrated Approach to Studying Mechanisms of Speech Production and Swallow Function in Down SyndromeNIHNational Institute on Deafness and Other Communication Disorders2023$1,959,062April 15, 2023March 31, 2026WILKINSON, KRISTA Mreporter.nih.gov
Function and regulation of copper in mammalian tissue differentiationNIHNational Institute of General Medical Sciences2022 to 2025$1,951,877August 1, 2022May 31, 2027VEST, KATHERINE ELIZABETHreporter.nih.gov
Family caregivers in later life: A longitudinal study of well-being and mental health in families of adults with autism and developmental disabilitiesNIHNational Institute on Aging2023 to 2025$1,947,044March 15, 2023February 29, 2028LORD, CATHERINEreporter.nih.gov
Improving pregnancy outcomes for women with intellectual and developmental disabilities in MedicaidNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,946,618April 1, 2023January 31, 2028RUBENSTEIN, ERIC Sreporter.nih.gov
Identification of Potential Biomarkers and Clinical Tools for use in Mucopolysaccharidosis IIIC Patients.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,944,180July 1, 2024June 30, 2027SINGAMSETTY, SRIKANTHreporter.nih.gov
Multidimensional investigation of auditory dysfunction in Down syndromeNIHNational Institute on Deafness and Other Communication Disorders2024 to 2025$1,942,611May 3, 2024April 30, 2029ESPINOSA, JOAQUIN M.reporter.nih.gov
A Novel Approach to Molecular Cell Pathologies of Human Down Syndrome and DS-ADNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,938,999September 12, 2017March 31, 2026LAWRENCE, JEANNE BENTLEYreporter.nih.gov
Fetal alcohol exposure and cerebrovascular developmentNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,937,828March 1, 2021February 28, 2027JIANG, HUABEIreporter.nih.gov
Dual roles of Nell-1 in craniofacial bones and brain through interaction with Cntnap4NIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,936,998August 1, 2020July 31, 2025SOO, CHIAreporter.nih.gov
Early developmental mechanisms of Rett SyndromeNIHNational Institute of Mental Health2021 to 2025$1,936,688December 1, 2009January 31, 2027SUR, MRIGANKAreporter.nih.gov
Genomic analysis of the Multiplex, Autozygous Populations in Cerebral Palsy (MAP CP) cohort: a focused approach to a complex diseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,933,393February 1, 2023January 31, 2028KRUER, MICHAEL Creporter.nih.gov
Molecular and circuit defects underlying different SCN2A mutations and ASDsNIHNational Institute of Mental Health2021 to 2023$1,930,230June 7, 2019March 31, 2025PITT, GEOFFREY Sreporter.nih.gov
The Effects of Somatosensory Experience on Brain Development and Function in Autism Spectrum DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,928,538July 15, 2021June 30, 2027OREFICE, LAUREN LYNNreporter.nih.gov
Leveraging Telehealth to Identify Infants at Elevated Likelihood for Autism in the First Year of lifeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,927,578August 15, 2023May 31, 2028TALBOTT, MEAGAN RUTHreporter.nih.gov
Neuronal hyperexcitability and seizures in a Scn2a deficient mouse modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,925,875July 15, 2021April 30, 2027YANG, YANGreporter.nih.gov
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health ServicesNIHNational Institute of Mental Health2024 to 2025$1,923,430September 4, 2024May 31, 2029DICKSON, KELSEY Sreporter.nih.gov
Role of SCN2A in Myelination and Neural Circuit Development in Autism Spectrum DisorderNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$1,921,777September 1, 2021August 31, 2026KIM, JUN HEEreporter.nih.gov
Validation of the online Toddler Autism and Development Adaptive Screener (TADAS) at 18 monthsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,920,148September 1, 2022August 31, 2025HOWARD, BARBARA JOreporter.nih.gov
Serotonergic modulation of excitatory synapse formation and maturation during developmentNIHNational Institute of Mental Health2021 to 2025$1,918,500December 1, 2020October 31, 2026OH, WON CHANreporter.nih.gov
Construction of the integrated human cortical organoids to investigate neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2023$1,916,931September 9, 2019July 31, 2025PARK, IN-HYUNreporter.nih.gov
Investigation of Pitt-Hopkins Syndrome pathophysiology using a human modelNIHNational Institute of Mental Health2021 to 2025$1,915,229March 5, 2021December 31, 2025MUOTRI, ALYSSON R.reporter.nih.gov
Mediator kinases as interferon antagonists in Down SyndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,912,701September 22, 2020August 31, 2025TAATJES, DYLAN Jreporter.nih.gov
Prenatal Alcohol and Anxiety: An Ontogenetic Role for CRFNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,912,538June 15, 2021March 31, 2027DIAZ, MARVIN RAFAELreporter.nih.gov
Understanding the effects of motor learning in wild-type and Mecp2-deficient miceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,912,399April 1, 2022March 31, 2027LU, HUIreporter.nih.gov
5/9: Dissecting the effects of genomic variants on neurobehavioral dimensions in CNVs enriched for neuropsychiatric disordersNIHNational Institute of Mental Health2021 to 2024$1,898,860June 20, 2019March 31, 2025VORSTMAN, JACOB A.S.reporter.nih.gov
Brain Development in Down Syndrome during Fetal and Early Postnatal AgesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$1,896,457September 18, 2024August 31, 2027TAKAHASHI (OKI), EMIreporter.nih.gov
Sensitivity of toddler screening: Integrating concurrent and prospective strategies to detect ASDNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,895,580April 10, 2023March 31, 2028ROBINS, DIANA Lreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Pittsburgh at PittsburghPittsburgh, PA21$106 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC76$95.4 million0$0
University of California at DavisDavis, CA69$88.8 million0$0
University of Colorado DenverAurora, CO53$85 million0$0
Yale UniversityNew Haven, CT46$83.1 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA38$80.7 million0$0
Washington UniversitySaint Louis, MO52$78.1 million0$0
University of California Los AngelesLos Angeles, CA62$76.3 million0$0
University of Wisconsin-MadisonMadison, WI55$74.2 million0$0
University of California, San FranciscoSan Francisco, CA50$71.1 million0$0
University of California, San DiegoLa Jolla, CA51$64.5 million0$0
Emory UniversityAtlanta, GA50$56 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY45$52.2 million0$0
Columbia University Health SciencesNew York, NY39$51.9 million0$0
University of WashingtonSeattle, WA25$49 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH26$47.4 million0$0
Broad Institute, Inc.Cambridge, MA10$42.6 million0$0
Baylor College of MedicineHouston, TX36$39.2 million0$0
Vanderbilt University Medical CenterNashville, TN27$36.7 million0$0
Duke UniversityDurham, NC23$36.6 million0$0
University of South Carolina at ColumbiaColumbia, SC21$35.3 million0$0
Drexel UniversityPhiladelphia, PA23$34.4 million0$0
University of Michigan at Ann ArborAnn Arbor, MI34$33.7 million0$0
Boston Children's HospitalBoston, MA35$32.7 million0$0
Stanford UniversityStanford, CA37$32 million0$0
Johns Hopkins UniversityBaltimore, MD30$31.4 million0$0
Massachusetts General HospitalBoston, MA27$29.8 million0$0
Oregon Health & Science UniversityPortland, OR21$28.5 million0$0
Ut Southwestern Medical CenterDallas, TX21$27.3 million0$0
University of PennsylvaniaPhiladelphia, PA45$26.7 million0$0
Weill Medical Coll of Cornell UnivNew York, NY17$26.4 million0$0
University of MinnesotaMinneapolis, MN19$23.5 million0$0
University of RochesterRochester, NY16$23.3 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA21$23.1 million0$0
University of FloridaGainesville, FL15$21.8 million0$0
Michigan State UniversityEast Lansing, MI12$21.2 million0$0
New York UniversityNew York, NY12$20.2 million0$0
San Diego State University FoundationSan Diego, CA22$19.6 million0$0
Columbia UniversityNew York, NY3$18.3 million0$0
University of Southern CaliforniaLos Angeles, CA19$18.3 million0$0
Northwestern University at ChicagoChicago, IL19$17.1 million0$0
Ohio State UniversityColumbus, OH15$16.9 million0$0
Colorado State UniversityFort Collins, CO10$15.8 million0$0
Seattle Children's HospitalSeattle, WA12$15.1 million0$0
University of VirginiaCharlottesville, VA9$15 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ16$14.6 million0$0
Brown UniversityProvidence, RI8$14.5 million0$0
Indiana University IndianapolisIndianapolis, IN10$14 million0$0
New York University School of MedicineNew York, NY9$14 million0$0
Wayne State UniversityDetroit, MI9$13.4 million0$0
Children's Research InstituteWashington, DC12$12.9 million0$0
Trustees of Boston UniversityBoston, MA13$12.9 million0$0
Medical University of South CarolinaCharleston, SC7$12.8 million0$0
University of Kansas Medical CenterKansas City, KS11$12.5 million0$0
University of Colorado at BoulderBoulder, CO9$12.2 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM16$12 million0$0
University of Kansas Center for Research IncLawrence, KS16$12 million0$0
University of Texas at AustinAustin, TX16$12 million0$0
Florida State UniversityTallahassee, FL5$11.9 million0$0
Lieber Institute, Inc.Baltimore, MD5$11.7 million0$0
Albert Einstein College of MedicineBronx, NY15$11.4 million0$0
Northwestern UniversityChicago, IL8$11.3 million0$0
Boston University Medical CampusBoston, MA11$11 million0$0
Phoenix Nest, Inc.Brooklyn, NY4$10.9 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA8$10.7 million0$0
Children's Hospital of Los AngelesLos Angeles, CA8$10.4 million0$0
University of California-BerkeleyBerkeley, CA13$10.3 million0$0
University of ArizonaTucson, AZ10$10 million0$0
Brigham and Women's HospitalBoston, MA9$9.9 million0$0
Virginia Commonwealth UniversityRichmond, VA9$9.7 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL11$9.6 million0$0
Research Triangle InstituteResearch Triangle Park, NC5$9.4 million0$0
University of Maryland BaltimoreBaltimore, MD10$9.4 million0$0
University of ChicagoChicago, IL5$9.3 million0$0
Dartmouth CollegeHanover, NH6$9.1 million0$0
Vanderbilt UniversityNashville, TN17$9 million0$0
Purdue UniversityWest Lafayette, IN10$8.6 million0$0
Kaiser Foundation Research InstituteOakland, CA9$8.5 million0$0
University of California-IrvineIrvine, CA9$8.2 million0$0
J. David Gladstone InstitutesSan Francisco, CA4$8.2 million0$0
George Washington UniversityWashington, DC5$8.1 million0$0
University of Alabama at BirminghamBirmingham, AL9$7.9 million0$0
Research Inst Nationwide Children's HospColumbus, OH8$7.9 million0$0
University of California-Santa CruzSanta Cruz, CA4$7.7 million0$0
University of IowaIowa City, IA7$7.7 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA5$7.5 million0$0
University of Illinois at ChicagoChicago, IL7$7.4 million0$0
Texas A&m Agrilife ResearchCollege Station, TX5$7.4 million0$0
Scripps Research Institute, theLa Jolla, CA3$7.4 million0$0
Rutgers University New BrunswickNew Brunswick, NJ6$7.3 million0$0
Women and Infants Hospital-Rhode IslandProvidence, RI2$7.3 million0$0
Omnitec Solutions, Inc.Bethesda, MD1$7.2 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA10$7.1 million0$0
University of ConnecticutStorrs, CT9$7.1 million0$0
University of South FloridaTampa, FL7$7.1 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA13$7 million0$0
SUNY at BuffaloAmherst, NY10$6.7 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY4$6.7 million0$0
Father Flanagan's Boys' HomeBoys Town, NE4$6.7 million0$0
Rockefeller UniversityNew York, NY7$6.6 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,074$648,901,8010$0
20241,146$599,828,2310$0
20231,126$598,605,1270$0
20221,084$544,999,5900$0
20211,025$509,585,4180$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 6 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 6 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 6 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 4 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIHNovember 24, 2026Not listedNotice number printed on 1 award here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIHJuly 17, 2027Not listedNotice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)PAR-25-255NIH93.242November 5, 2026Not listedSame assistance listing 93.242 as 653 awards here
Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)RFA-MH-27-150NIH93.242November 13, 2026Not listedSame assistance listing 93.242 as 653 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.242November 16, 2026$50,000Same assistance listing 93.242 as 653 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.242November 18, 2026Not listedSame assistance listing 93.242 as 653 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.242November 18, 2026Not listedSame assistance listing 93.242 as 653 awards here
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)PAR-25-226NIH93.242November 19, 2026Not listedSame assistance listing 93.242 as 653 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.242December 3, 2026Not listedSame assistance listing 93.242 as 653 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.242December 3, 2026Not listedSame assistance listing 93.242 as 653 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.242December 4, 2026Not listedSame assistance listing 93.242 as 653 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.242January 7, 2027$375,000Same assistance listing 93.242 as 653 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.