Data / Research funding / Induced Pluripotent Stem Cell Research
Induced Pluripotent Stem Cell Research: 1,241 NIH awards ($2B) to 233 organizations
1,241 NIH awards ($2B) in the NIH spending category Induced Pluripotent Stem Cell Research, to 233 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.
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Awards
The 500 largest of 1,241 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | NIH | National Institute on Aging | 2021 to 2025 | $65,403,220 | July 15, 2002 | May 31, 2027 | FOROUD, TATIANA M. | reporter.nih.gov |
| Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical Trial | NIH | National Institute on Aging | 2021 to 2025 | $28,784,116 | August 15, 2019 | April 30, 2027 | BRINTON, ROBERTA EILEEN | reporter.nih.gov |
| EO14042 DEVELOPMENT, STATISTICAL DESIGN, MONITORING AND COORDINATION OF VISION CLINICAL TRIALS AND EPIDEMIOLOGY RESEARCH | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $25,277,032 | November 1, 2021 | October 31, 2026 | MENEZES, SUPRIYA | reporter.nih.gov |
| The Origins of Alzheimer Disease in African Americans | NIH | National Institute on Aging | 2022 to 2025 | $20,889,453 | September 15, 2022 | June 30, 2027 | PERICAK-VANCE, MARGARET A. | reporter.nih.gov |
| Replication Study of Off-Target Assays for Guide RNAs in CRISPR-Based Therapeutics | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $17,077,732 | December 1, 2024 | April 30, 2025 | SAHA, KRISHANU | reporter.nih.gov |
| Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | NIH | National Institute on Aging | 2021 to 2025 | $15,514,157 | September 30, 2021 | May 31, 2027 | ELLERBY, LISA M | reporter.nih.gov |
| Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategies | NIH | National Institute on Aging | 2022 to 2025 | $14,689,794 | September 15, 2019 | December 31, 2026 | PERLS, THOMAS T | reporter.nih.gov |
| Personalized Modeling of CAR-T Cell Immunotherapy Using iPSC-Derived Effectors and Patient- Derived Tumor Organoids | NIH | National Cancer Institute | 2023 to 2025 | $12,675,268 | March 1, 1997 | August 31, 2026 | LIBUTTI, STEVEN K. | reporter.nih.gov |
| Advancing brain health research through male germline editing in marmosets | NIH | National Institute on Drug Abuse | 2021 to 2025 | $12,061,296 | August 1, 2021 | May 31, 2027 | HERMANN, BRIAN PETER | reporter.nih.gov |
| Supplement to TR01 Human cortical development and neural plasticity altered by trisomy 21 | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $11,380,369 | September 10, 2021 | August 31, 2027 | BHATTACHARYYA, ANITA | reporter.nih.gov |
| Site-Directed RNA Editing of Nav1.7 as a Novel Analgesic | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $11,194,636 | September 23, 2021 | August 31, 2027 | ROSENTHAL, JOSHUA J.C. | reporter.nih.gov |
| Scientific Management and Support to the National Institute of Mental Health (NIMH) Repository and Genomics Resource (NRGR) | NIH | National Institute on Drug Abuse | 2025 | $10,685,838 | August 11, 2025 | August 10, 2026 | reporter.nih.gov | |
| Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSP | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $9,418,230 | September 1, 2021 | August 31, 2026 | GOATE, ALISON M | reporter.nih.gov |
| Identification of TDP-43 Modifiers Through Single-Cell Transcriptional and Epigenomic Dissection of ALS and FTLD-MND | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $9,106,321 | September 29, 2021 | August 31, 2026 | DONNELLY, CHRISTOPHER JAMES | reporter.nih.gov |
| High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes | NIH | National Human Genome Research Institute | 2021 to 2025 | $8,874,835 | September 1, 2021 | May 31, 2027 | GERSBACH, CHARLES A. | reporter.nih.gov |
| Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions | NIH | National Institute on Aging | 2021 to 2025 | $8,654,669 | July 1, 2021 | June 30, 2027 | TEMPLE, SALLY | reporter.nih.gov |
| Alzheimer variants: Propagation of shared functional changes across cellular networks | NIH | National Institute on Aging | 2021 to 2025 | $8,542,236 | July 15, 2021 | June 30, 2027 | DE JAGER, PHILIP L | reporter.nih.gov |
| Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for Schizophrenia | NIH | National Institute of Mental Health | 2021 to 2025 | $8,050,699 | April 1, 2021 | January 31, 2027 | CRAWFORD, GREGORY E | reporter.nih.gov |
| Higher Order Chromatin and Genetic Risk for Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $7,828,464 | September 1, 2015 | May 31, 2027 | ROUSSOS, PANAGIOTIS | reporter.nih.gov |
| Restoring Vision with High-Fidelity Nonsense Codon Correction | NIH | National Eye Institute | 2021 to 2025 | $7,812,597 | February 1, 2021 | November 30, 2026 | PATTNAIK, BIKASH RANJAN | reporter.nih.gov |
| JAX MorPhiC Data Production Center | NIH | National Human Genome Research Institute | 2022 to 2025 | $7,698,185 | August 4, 2022 | May 31, 2027 | ROBSON, PAUL | reporter.nih.gov |
| Therapeutics targeting TDP-43 to treat Alzheimer's disease and related disorders | NIH | National Institute on Aging | 2021 to 2025 | $7,375,647 | July 1, 2021 | December 31, 2026 | REITZ, ALLEN BERNARD | reporter.nih.gov |
| Center for scalable knockout and multimodal phenotyping in genetically diverse human genomes | NIH | National Human Genome Research Institute | 2022 to 2025 | $7,316,442 | August 15, 2022 | May 31, 2027 | HUANGFU, DANWEI | reporter.nih.gov |
| Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy Aging | NIH | National Institute on Aging | 2022 to 2025 | $7,239,829 | August 15, 2022 | June 30, 2027 | CRUCHAGA, CARLOS | reporter.nih.gov |
| Overcoming Barriers to retinal ganglion cell replacement in experimental glaucoma | NIH | National Eye Institute | 2021 to 2025 | $7,031,142 | September 30, 2021 | July 31, 2027 | MEYER, JASON STEPHEN | reporter.nih.gov |
| Primary Open Angle African-American Glaucoma Genetics Study Renewal | NIH | National Eye Institute | 2021 to 2025 | $6,924,827 | April 1, 2014 | March 31, 2026 | O'BRIEN, JOAN M | reporter.nih.gov |
| Functional genomic studies in diverse populations to characterize risk loci for Alzheimer Disease | NIH | National Institute on Aging | 2021 to 2025 | $6,908,458 | July 15, 2021 | June 30, 2027 | VANCE, JEFFERY MARVIN | reporter.nih.gov |
| The NINDS Human Cell and Data Repository (U24 renewal) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $6,898,547 | September 30, 2015 | July 31, 2030 | KNOWLES, JAMES A | reporter.nih.gov |
| Precision Editing of Granulin Mutations that Cause Frontotemporal Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $6,580,415 | August 15, 2025 | July 31, 2029 | SONTHEIMER, ERIK J. | reporter.nih.gov |
| Spatial multiomic mapping of gene function with CRISPRoff | NIH | National Human Genome Research Institute | 2022 to 2025 | $6,562,020 | September 1, 2022 | June 30, 2027 | GILBERT, LUKE | reporter.nih.gov |
| Molecular and cellular characterization of essential human genes. | NIH | National Human Genome Research Institute | 2022 to 2025 | $6,526,413 | September 22, 2022 | June 30, 2027 | ADLI, MAZHAR | reporter.nih.gov |
| The effects of Alzheimer's disease risk genes on metabolism and signaling across cell types | NIH | National Institute on Aging | 2022 to 2025 | $6,477,664 | September 19, 2022 | August 31, 2027 | FRAENKEL, ERNEST | reporter.nih.gov |
| The impact of genomic variation on environment-induced changes in pancreatic beta cell states | NIH | National Human Genome Research Institute | 2021 to 2025 | $6,348,795 | September 7, 2021 | May 31, 2027 | CARTER, HANNAH KATHRYN | reporter.nih.gov |
| Elucidate the roles of Alzheimer's disease risk genes and variants in gene expression and AD-related phenotypes | NIH | National Institute on Aging | 2022 to 2025 | $6,109,739 | September 15, 2022 | August 31, 2027 | SHEN, YIN | reporter.nih.gov |
| Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency | NIH | National Human Genome Research Institute | 2021 to 2025 | $6,016,057 | September 1, 2021 | May 31, 2027 | LUO, CHONGYUAN | reporter.nih.gov |
| Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics | NIH | National Human Genome Research Institute | 2021 to 2025 | $6,001,599 | September 1, 2021 | May 31, 2026 | WU, HAO | reporter.nih.gov |
| Dissecting the role of sex-linked genes and APOE e4 risk in AD | NIH | National Institute on Aging | 2021 to 2025 | $5,928,484 | September 30, 2021 | July 31, 2027 | YOUNG, JESSICA ELAINE | reporter.nih.gov |
| Chaperome networks in Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $5,927,093 | February 15, 2021 | January 31, 2027 | CHIOSIS, GABRIELA | reporter.nih.gov |
| NPTX2: Preserving memory circuits in normative aging and Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $5,697,103 | May 1, 2021 | April 30, 2027 | BARNES, CAROL A. | reporter.nih.gov |
| Mechanistic Analysis of Genetic Modifiers in Parkinson's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,598,826 | May 1, 2021 | April 30, 2029 | KRAINC, DIMITRI | reporter.nih.gov |
| Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimer’s Disease | NIH | National Institute on Aging | 2021 to 2025 | $5,445,522 | September 30, 2021 | May 31, 2027 | KELLIS, MANOLIS | reporter.nih.gov |
| Assay and Data Generation Center (ADGC) for the Model of iPSC-derived Neurons for NPD (MiNND) | NIH | National Institute of Mental Health | 2023 to 2025 | $5,271,743 | May 17, 2023 | April 30, 2028 | PANG, ZHIPING P. | reporter.nih.gov |
| Continuous Neurogenesis in the Mammalian Hippocampus | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,244,633 | May 1, 2020 | April 30, 2028 | SONG, HONGJUN | reporter.nih.gov |
| Targeting Dysregulated RNA Splicing in Neurodegenerative Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $5,093,143 | September 1, 2023 | August 31, 2028 | LAGIER-TOURENNE, CLOTILDE | reporter.nih.gov |
| A Precision Medicine Approach for the Study of Targetable Pathways in Vascular Dementia | NIH | National Institute on Aging | 2022 to 2025 | $5,086,657 | February 1, 2022 | November 30, 2026 | GOATE, ALISON M | reporter.nih.gov |
| Toward a Mechanism-Based Approach to Treating Cardiac Arrhythmia | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $5,079,600 | March 6, 2019 | February 28, 2026 | KNOLLMANN, BJORN C | reporter.nih.gov |
| UCLA High-Throughput Neuropsychiatric Disorder Phenotyping Center (UCLA HT-NPC) | NIH | National Institute of Mental Health | 2023 to 2025 | $5,035,081 | May 1, 2023 | April 30, 2028 | GESCHWIND, DANIEL H | reporter.nih.gov |
| Multiethnic genomic epigenomic and transcriptomic fine-mapping and functional validation analysis of schizophrenia and bipolar disorder risk loci | NIH | National Institute of Mental Health | 2021 to 2025 | $4,996,628 | January 1, 2021 | October 31, 2026 | ROUSSOS, PANAGIOTIS | reporter.nih.gov |
| Leveraging Natural Phenotypic Variations of Heterogenous ALS Populations-in-a-Dish to Enable Scalable Drug Discovery | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $4,949,698 | September 18, 2022 | August 31, 2027 | ICHIDA, JUSTIN KAWIKA | reporter.nih.gov |
| Experimental Cellular Approaches to Genotype × Environment Interaction | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $4,934,544 | September 7, 2023 | August 31, 2028 | CURRAN, JOANNE E. | reporter.nih.gov |
| Modeling drugs of abuse-HIV interactions using iPSC-derived human cerebral organoids | NIH | National Institute on Drug Abuse | 2021 to 2025 | $4,890,555 | September 30, 2021 | July 31, 2026 | SANNA, PIETRO P | reporter.nih.gov |
| Establishing patient-derived iPSCs as a platform for discovery research in NAFLD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $4,780,391 | June 1, 2023 | March 31, 2028 | MAHER, JACQUELYN J. | reporter.nih.gov |
| Development of Innovative Resources to Advance MDS Research | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $4,661,966 | September 15, 2023 | July 31, 2028 | BLEAKLEY, MARIE | reporter.nih.gov |
| Altering Cardiac Cell Fate for Heart Repair | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,621,749 | January 13, 2021 | November 30, 2027 | QIAN, LI | reporter.nih.gov |
| Mechanisms underlying gastric intestinal metaplasia and carcinogenesis | NIH | National Cancer Institute | 2022 to 2025 | $4,560,310 | September 20, 2022 | August 31, 2027 | RUSTGI, ANIL K | reporter.nih.gov |
| Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,345,357 | December 16, 2015 | May 31, 2028 | WU, JOSEPH C. | reporter.nih.gov |
| Data science approaches to autism: environmental modulators of the transcriptome and gene-x-environment interactions | NIH | Office of the Director, National Institutes of Health | 2025 | $4,255,873 | September 29, 2025 | September 28, 2028 | GESCHWIND, DANIEL H | reporter.nih.gov |
| Microglia contribution to disease pathogenesis in C9orf72 ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,229,195 | September 1, 2021 | August 31, 2027 | SATTLER, RITA | reporter.nih.gov |
| Pathogenic Mechanisms in Christianson Syndrome and NHE6-Related Disorders | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,197,634 | September 15, 2019 | June 30, 2029 | MORROW, ERIC M | reporter.nih.gov |
| High-throughput in vivo and in vitro functional and multi-omics screens of neuropsychiatric and neurodevelopmental disorder risk genes | NIH | National Institute of Mental Health | 2023 to 2025 | $4,152,990 | May 1, 2023 | April 30, 2028 | HOFFMAN, ELLEN J | reporter.nih.gov |
| Biospecimen procurement and tissue microarray manufacture for the CHTN | NIH | National Cancer Institute | 2021 to 2025 | $4,152,759 | April 1, 2019 | March 31, 2029 | MOSKALUK, CHRISTOPHER A. | reporter.nih.gov |
| Resolving complex alternative splicing of psychiatric disease genes using single-cell approaches | NIH | National Institute of Mental Health | 2021 to 2025 | $4,123,629 | August 5, 2021 | May 31, 2026 | FANG, GANG | reporter.nih.gov |
| Functional convergence following disruption of diverse genes associated with neurodevelopmental disorders | NIH | National Institute of Mental Health | 2021 to 2025 | $4,120,229 | May 20, 2021 | March 31, 2027 | BRENNAND, KRISTEN JENNIFER | reporter.nih.gov |
| Understanding the functional impacts of Aβ variants in Alzheimer's disease with human brain organoids | NIH | National Institute on Aging | 2022 to 2025 | $4,119,330 | August 1, 2022 | July 31, 2027 | WEN, ZHEXING | reporter.nih.gov |
| Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $4,070,240 | August 1, 2021 | May 31, 2026 | HUANG, YADONG | reporter.nih.gov |
| Nuclear pore complex quality control in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,005,112 | May 1, 2021 | April 30, 2026 | ROTHSTEIN, JEFFREY D | reporter.nih.gov |
| Engineered Stem Cells for Cardiac Repair | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,984,462 | February 1, 2018 | March 31, 2027 | REGNIER, MICHAEL | reporter.nih.gov |
| Drug repositioning for Alzheimer's disease via genetics, electronic health records, and human iPSC models | NIH | National Institute on Aging | 2021 to 2025 | $3,970,571 | April 15, 2021 | December 31, 2026 | LI, BINGSHAN | reporter.nih.gov |
| Impaired activity-dependent protein synthesis in dendrites and pathophysiology in tauopathy | NIH | National Institute on Aging | 2021 to 2025 | $3,904,840 | August 1, 2021 | July 31, 2027 | TRACY, TARA | reporter.nih.gov |
| Osteoarthritis Progression And Sensory Pathway Alterations | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,899,677 | May 1, 2013 | July 31, 2029 | MALFAIT, ANNE-MARIE | reporter.nih.gov |
| Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,869,226 | May 1, 2018 | May 31, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Gaining insight into psychiatric disease by engineering piece by piece the human brain in vitro | NIH | National Institute of Mental Health | 2025 | $3,812,108 | August 1, 2015 | August 19, 2029 | PASCA, SERGIU | reporter.nih.gov |
| Harnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,810,605 | February 1, 2021 | January 31, 2028 | GUNDRY, REBEKAH L. | reporter.nih.gov |
| TDP-43 acetylation, phase separation, aggregation, and clearance by antibody-mediated degradation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,806,187 | April 1, 2021 | March 31, 2026 | CLEVELAND, DON W | reporter.nih.gov |
| Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | NIH | National Institute on Aging | 2022 to 2025 | $3,748,222 | September 1, 2022 | May 31, 2027 | HUANG, YADONG | reporter.nih.gov |
| Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,747,870 | August 1, 2021 | May 31, 2027 | AKBARIAN, SCHAHRAM | reporter.nih.gov |
| Genomic and functional characterization of ASD and ID-associated MYT1L mutation | NIH | National Institute of Mental Health | 2021 to 2025 | $3,747,342 | December 1, 2020 | October 31, 2026 | KROLL, KRISTEN L | reporter.nih.gov |
| Cilia in Heart Development and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,728,670 | February 15, 2019 | January 31, 2026 | BRUECKNER, MARTINA | reporter.nih.gov |
| Cardiogenesis: Molecular Mechanisms | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,717,603 | January 10, 1997 | May 31, 2028 | SRIVASTAVA, DEEPAK | reporter.nih.gov |
| Systematic Functional Interpretation of Regulatory Variants in Neuropsychiatric Disorders | NIH | National Institute of Mental Health | 2021 to 2025 | $3,689,169 | May 4, 2016 | January 31, 2027 | DUAN, JUBAO | reporter.nih.gov |
| The role of ABI3 in Alzheimers disease | NIH | National Institute on Aging | 2021 to 2025 | $3,667,316 | September 30, 2021 | May 31, 2027 | KIM, JUNGSU | reporter.nih.gov |
| Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | NIH | National Institute on Aging | 2021 to 2025 | $3,657,244 | March 1, 2021 | November 30, 2026 | KELLIS, MANOLIS | reporter.nih.gov |
| Neurotoxic and neurodegenerative risks from chronic exposure to metal mixtures in e-cigarette aerosol | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $3,656,277 | September 8, 2021 | June 30, 2027 | RE, DIANE BERENGERE | reporter.nih.gov |
| Emulating Immune Dysregulation by Trisomy 21 in a Multi-Organ-on-a-Chip System | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,649,414 | September 20, 2021 | July 31, 2026 | HAJIPOURAN BENAM, KAMBEZ | reporter.nih.gov |
| Nuclear and Glial Dysfunction in Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,647,532 | May 16, 2023 | April 30, 2031 | ROTHSTEIN, JEFFREY D | reporter.nih.gov |
| FunGen-xQTL: Unraveling the genetic basis of molecular functions in Alzheimer's Disease | NIH | National Institute on Aging | 2025 | $3,642,232 | August 5, 2025 | July 31, 2030 | WANG, GAO | reporter.nih.gov |
| Immunovascular interactions in postoperative delirium superimposed on dementia (DSD). | NIH | National Institute on Aging | 2022 to 2025 | $3,624,866 | September 15, 2022 | August 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Intranasal Treatment of Stem Cell-derived Extracellular Vesicles for Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,620,000 | August 1, 2022 | July 31, 2027 | SHETTY, ASHOK K | reporter.nih.gov |
| Targeting the NLRP3 Inflammasome to Mitigate Neuroinflammation and HIV Persistence in the CNS: Mechanisms and Therapeutic Strategies | NIH | National Institute of Mental Health | 2025 | $3,613,504 | September 22, 2025 | September 21, 2029 | SWARTZ, TALIA H | reporter.nih.gov |
| Origin of Cortical Species-specific Distinctions | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,571,176 | April 1, 2025 | March 31, 2030 | RAKIC, PASKO | reporter.nih.gov |
| Predicting and Preventing Chemotherapy-Induced Cardiotoxicity in African American Children | NIH | National Cancer Institute | 2021 to 2025 | $3,570,931 | August 5, 2021 | July 31, 2026 | BURRIDGE, PAUL W. | reporter.nih.gov |
| Human iPSC Model to Elucidate Metabolic Interplay in Diabetic Cardimyopathy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,569,593 | April 1, 2019 | April 30, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Inter- and Intra-cellular effects of cannabinoids, HIV and ART in the CNS | NIH | National Institute on Drug Abuse | 2021 to 2025 | $3,529,874 | August 1, 2020 | May 31, 2027 | JORDAN-SCIUTTO, KELLY L | reporter.nih.gov |
| Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic risk | NIH | National Institute of Mental Health | 2021 to 2025 | $3,528,182 | February 12, 2021 | December 31, 2026 | NICOL, GINGER E | reporter.nih.gov |
| JAK-STAT Inhibition to Reduce Racial Disparities in Kidney Disease | NIH | National Institute on Minority Health and Health Disparities | 2021 to 2025 | $3,524,489 | September 20, 2021 | May 31, 2027 | OLABISI, OPEYEMI AYODEJI | reporter.nih.gov |
| Impact of the Human Herpesvirus 6A (HHV6A) latency gene U94A on Alzheimer disease pathology | NIH | National Institute on Aging | 2021 to 2025 | $3,507,363 | September 30, 2021 | May 31, 2026 | MAYER-PROSCHEL, MARGOT | reporter.nih.gov |
| Biochemical and cellular mechanisms linking actin mutations to visceral myopathy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,487,348 | September 28, 2021 | August 31, 2027 | HEUCKEROTH, ROBERT O | reporter.nih.gov |
| Probing Heterogeneity of Alzheimer's Disease Using iPSCs | NIH | National Institute on Aging | 2021 to 2025 | $3,479,050 | July 15, 2018 | April 30, 2028 | YOUNG-PEARSE, TRACY L | reporter.nih.gov |
| Resolving the function of progranulin in lysosomal lipid metabolism and the etiology of Alzheimer's disease and frontotemporal dementia | NIH | National Institute on Aging | 2022 to 2025 | $3,471,933 | September 1, 2022 | August 31, 2027 | KUKAR, THOMAS L | reporter.nih.gov |
| Modeling functional genomics of susceptibility to the persistent effects of environmental toxins in an elderly rural Indiana neurodegenerative cohort | NIH | National Institute on Aging | 2022 to 2025 | $3,385,412 | September 15, 2022 | May 31, 2027 | BOWMAN, AARON B | reporter.nih.gov |
| Cellular and molecular mechanisms underlying DDX3X syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,350,844 | January 1, 2021 | November 30, 2026 | SILVER, DEBRA L. | reporter.nih.gov |
| Unraveling the molecular pathology of retinal degeneration through single cell genomics | NIH | National Eye Institute | 2021 to 2025 | $3,347,817 | June 1, 2021 | May 31, 2027 | AYYAGARI, RADHA | reporter.nih.gov |
| Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a Screens | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,345,164 | September 1, 2025 | August 31, 2030 | WU, JOSEPH C. | reporter.nih.gov |
| Role of Energy Metabolism in Patterning the Vertebrate Musculo-Skeletal Axis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,337,554 | March 1, 2016 | March 31, 2026 | POURQUIE, OLIVIER | reporter.nih.gov |
| Why do Down Syndrome patients have high risk of Hirschsprung disease? | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $3,330,453 | September 15, 2022 | July 31, 2027 | CHAKRAVARTI, ARAVINDA | reporter.nih.gov |
| Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCs | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,324,533 | August 1, 2018 | June 30, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Investigating aberrant vesicular degradation and lipid metabolism in neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,323,710 | August 15, 2025 | July 31, 2029 | BOSCO, DARYL ANGELA | reporter.nih.gov |
| Leveraging 3D bioprinted organoid constructs to pattern and model human brain development | NIH | National Institute of Mental Health | 2021 to 2025 | $3,321,612 | April 1, 2021 | January 31, 2026 | SLOAN, STEVEN A | reporter.nih.gov |
| Proteogenetics of Autism Spectrum Disorders | NIH | National Institute of Mental Health | 2021 to 2025 | $3,288,305 | August 1, 2013 | June 30, 2027 | YATES III, JOHN R | reporter.nih.gov |
| Genetically Programmed Pancreatic Organoids with Self-Adaptive Multi-Lineage Population Control | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,243,464 | September 1, 2021 | August 31, 2026 | WEISS, RON | reporter.nih.gov |
| TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimers Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,240,062 | July 15, 2022 | March 31, 2027 | CHENG, FEIXIONG | reporter.nih.gov |
| Multi-Targeting Oligonucleotide Therapeutics for Familial and Sporadic Amyotrophic Lateral Sclerosis | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,236,744 | May 15, 2019 | May 31, 2029 | WATTS, JONATHAN K | reporter.nih.gov |
| Developing second generation SCID pig models: filling the gaps to improve translation of therapeutics in regenerative medicine | NIH | Office of the Director, National Institutes of Health | 2021 to 2025 | $3,219,338 | February 15, 2020 | July 31, 2029 | TUGGLE, CHRISTOPHER | reporter.nih.gov |
| Reprogramming and Directed Differentiation of Skeletal Muscle Cells from hPSCs | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $3,204,262 | September 20, 2013 | June 30, 2028 | PYLE, APRIL D | reporter.nih.gov |
| Directing Fate, Subtype Identity and Survival in Human Pluripotent-Derived Midbrain Dopamine Neurons | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,203,281 | April 1, 2021 | March 31, 2027 | STUDER, LORENZ P. | reporter.nih.gov |
| Assessing Effects of Microgravity on Cardiovascular Aging with AI and 3D Organoids | NIH | National Center for Advancing Translational Sciences | 2025 | $3,183,188 | August 1, 2025 | June 30, 2028 | WU, JOSEPH C. | reporter.nih.gov |
| Developing preclinical xenograft models in zebrafish. | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $3,178,512 | March 1, 2022 | February 28, 2026 | LANGENAU, DAVID MICHAEL | reporter.nih.gov |
| Single-cell Multi-omic Profiling of Drug Responses Using Pooled iPSC-CM Differentiation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,175,574 | May 1, 2019 | April 30, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Microphysiological Model of Human Cardiac Sympathetic Innervation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,165,021 | July 1, 2022 | June 30, 2027 | KIM, DEOK-HO | reporter.nih.gov |
| A new brain organoid model for NeuroHIV and the impact of opioids | NIH | National Institute on Drug Abuse | 2022 to 2025 | $3,149,557 | September 30, 2022 | August 31, 2027 | MUOTRI, ALYSSON R. | reporter.nih.gov |
| Engineering Vascularized Cardiac Muscle | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,149,452 | July 1, 2005 | March 31, 2027 | VUNJAK-NOVAKOVIC, GORDANA | reporter.nih.gov |
| Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism | NIH | National Institute of Mental Health | 2022 to 2025 | $3,142,634 | March 5, 2022 | December 31, 2026 | MUOTRI, ALYSSON R. | reporter.nih.gov |
| Harnessing Novel Human Endocrine Progenitor Biology for Enhanced Generation of Beta Cells from Stem Cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $3,140,632 | September 1, 2025 | August 31, 2029 | SNEDDON, JULIE BETH | reporter.nih.gov |
| Establishment of a causal link between AD and L1 retrotransposons | NIH | National Institute on Aging | 2022 to 2025 | $3,120,084 | September 15, 2022 | July 31, 2027 | MUOTRI, ALYSSON R. | reporter.nih.gov |
| ASH1L mediated transcription networks in autism spectrum disorders | NIH | National Institute of Mental Health | 2023 to 2025 | $3,119,859 | January 1, 2023 | December 31, 2026 | LIZARRAGA, SOFIA BEATRIZ | reporter.nih.gov |
| Hippocampal iPSC-Derived Assembloids to Model Interneuron and Circuit Vulnerability in Genetically-Encoded Amnestic and Behavioral Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,109,857 | August 1, 2025 | July 31, 2029 | REXACH, JESSICA E | reporter.nih.gov |
| Development of iPSCs for comparative genomics in primates | NIH | National Human Genome Research Institute | 2021 to 2025 | $3,092,654 | September 1, 2019 | April 30, 2027 | GILAD, YOAV | reporter.nih.gov |
| BIOLOGICAL EMBEDDING OF CONTEXTUAL FACTORS IN HUMAN STEM CELLS: IMPLICATIONS FOR POPULATION HEALTH DIFFERENCES | NIH | National Institute on Minority Health and Health Disparities | 2022 to 2025 | $3,074,250 | September 26, 2022 | June 30, 2027 | WADHWA, PATHIK D | reporter.nih.gov |
| Mechanism of stathmin-2-dependent axon maintenance, regeneration, and function | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,072,075 | April 1, 2020 | March 31, 2029 | CLEVELAND, DON W | reporter.nih.gov |
| The emerging role of apelin, RAAS, and ACE2 crosstalk in pulmonary hypertension | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,037,281 | August 1, 2022 | July 31, 2027 | FRUMP, ANDREA LEE | reporter.nih.gov |
| Molecular Drivers of Human Gliogenesis | NIH | National Institute of Mental Health | 2021 to 2025 | $3,033,949 | August 1, 2021 | May 31, 2026 | SLOAN, STEVEN A | reporter.nih.gov |
| Early cardiac progenitors | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,025,531 | July 1, 2013 | July 31, 2029 | BRUNEAU, BENOIT GAETAN | reporter.nih.gov |
| Modeling Inner Ear Differentiation with Pluripotent Stem Cells | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $3,024,653 | March 1, 2014 | May 31, 2029 | HASHINO, ERI | reporter.nih.gov |
| Heightened hypoxia and DNA methylation in heart defects of diabetic embryopathy | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,020,733 | September 15, 2022 | July 31, 2027 | YANG, PEIXIN | reporter.nih.gov |
| Generating Exogenic Organs for Transplantation without the Use of Immunosuppression | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $3,005,890 | September 21, 2022 | July 31, 2027 | STEER, CLIFFORD JOHN | reporter.nih.gov |
| In vivo Characterization of Regulatory Variant Pathogenicity in Congenital Heart Disease | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,998,900 | January 1, 2022 | December 31, 2026 | VISEL, AXEL | reporter.nih.gov |
| Pax6 as a key regulator of lens development | NIH | National Eye Institute | 2021 to 2025 | $2,996,871 | January 1, 2000 | May 31, 2026 | CVEKL, ALES | reporter.nih.gov |
| Unraveling the Genetic Programs Engaged in ASD Neurons Through Coupled Transcriptomic and Phenotypic Readouts | NIH | National Institute of Mental Health | 2022 to 2025 | $2,986,134 | August 10, 2022 | June 30, 2027 | FARHI, SAMOUIL | reporter.nih.gov |
| Investigating the role of Alzheimer's disease familial mutations in neuromuscular physiology | NIH | National Institute on Aging | 2022 to 2025 | $2,980,194 | May 15, 2022 | April 30, 2027 | HICKMAN, JAMES J | reporter.nih.gov |
| Alzheimer's Disease associated pathology induced by neurotropic viral infection | NIH | National Institute on Aging | 2021 to 2025 | $2,972,109 | September 30, 2021 | August 31, 2027 | MURPHY, EAIN A | reporter.nih.gov |
| Preclinical studies of pluripotent stem cell-derived myogenic progenitors in non-human primates | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,948,443 | August 6, 2021 | December 31, 2026 | PERLINGEIRO, RITA C. R. | reporter.nih.gov |
| RIGERR: Resources for Investigating Genetic and Epigenetic Regulation of Renal Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,915,414 | August 3, 2023 | July 31, 2027 | LIANG, MINGYU | reporter.nih.gov |
| Identification of metabolic alterations during cortical development in a human cellular model for 22q11.2 deletion syndrome | NIH | National Institute of Mental Health | 2022 to 2025 | $2,912,854 | January 18, 2022 | October 31, 2026 | PASCA, ANCA MIRABELA | reporter.nih.gov |
| iPSC-Derived Vascularized Human Lung Organoids and Interaction Between Lung Endothelial Cells and Alveolar Epithelial Cells | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,907,792 | August 1, 2022 | May 31, 2027 | REHMAN, JALEES | reporter.nih.gov |
| Alterations in Post-Receptor Insulin Signaling in Diabetes and Insulin Resistance | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,895,718 | September 17, 2021 | June 30, 2027 | KAHN, C RONALD | reporter.nih.gov |
| Elucidating the molecular mechanisms behind human neurodevelopmental disorders using brain organoids | NIH | National Institute of Mental Health | 2022 to 2025 | $2,876,812 | February 16, 2022 | December 31, 2026 | NOVITCH, BENNETT G | reporter.nih.gov |
| Neurotropic herpesvirus envelopment and microtubule-mediated transport | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,862,658 | March 15, 2017 | November 30, 2027 | WILSON, DUNCAN W. | reporter.nih.gov |
| Molecular genetic analyses of transcriptional dysregulation in Alzheimers disease | NIH | National Institute on Aging | 2022 to 2025 | $2,855,753 | July 15, 2022 | March 31, 2027 | KIM, JUNGSU | reporter.nih.gov |
| Investigation of the role of ATXN1 in oligodendroglia and neurodegenerative diseases | NIH | National Institute on Aging | 2022 to 2025 | $2,847,875 | March 1, 2022 | December 31, 2026 | LIM, JANGHOO | reporter.nih.gov |
| Functional mapping of noncoding regulatory variants in human neuronal subtypes3. | NIH | National Institute of Mental Health | 2022 to 2025 | $2,846,517 | March 18, 2022 | January 31, 2027 | YANG, NAN | reporter.nih.gov |
| Expression, Regulation and Function of the SULT1C Carcinogen-Activating Enzymes | NIH | National Institute of Environmental Health Sciences | 2021 to 2025 | $2,833,481 | January 8, 2014 | December 31, 2026 | RUNGE-MORRIS, MELISSA A | reporter.nih.gov |
| Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | NIH | National Institute on Aging | 2022 to 2025 | $2,827,960 | April 1, 2022 | January 31, 2026 | TSAI, LI-HUEI | reporter.nih.gov |
| Translational Control of Cardiac Excitability | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,825,151 | July 15, 2016 | June 30, 2026 | ROBERTSON, GAIL A | reporter.nih.gov |
| Investigating human cis-regulatory evolution with hybrid iPS cells | NIH | National Human Genome Research Institute | 2022 to 2025 | $2,824,455 | May 25, 2022 | March 31, 2026 | FRASER, HUNTER B | reporter.nih.gov |
| Production of Cultured Red Blood Cells | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,816,822 | September 15, 2015 | March 31, 2029 | BOUHASSIRA, ERIC E. | reporter.nih.gov |
| Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,816,253 | July 1, 2016 | November 30, 2026 | ZHANG, JIANYI | reporter.nih.gov |
| Exploiting accelerated aging associated with Low Earth Orbit (LEO) environment to gain insights into pathogenesis and treatment of progressive neurological disorders | NIH | National Institute on Aging | 2025 | $2,815,841 | September 1, 2025 | August 31, 2028 | SETHU, PALANIAPPAN | reporter.nih.gov |
| Analysis of protein interactions in neurodegenerative disease | NIH | National Institute on Aging | 2022 to 2025 | $2,811,410 | May 1, 2022 | April 30, 2027 | YATES III, JOHN R | reporter.nih.gov |
| Chromatin Dynamics During Epithelial Commitment | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,805,406 | September 1, 2024 | June 30, 2029 | ORO, ANTHONY E | reporter.nih.gov |
| Biomaterials Strategies to Promote Functional Recovery After Ischemic Stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,801,281 | March 1, 2020 | June 30, 2030 | SEGURA, TATIANA | reporter.nih.gov |
| Neural Circuits, Kinetics and Energetics HTS of Human iPSC-Neurons, -Microglia, and -Astrocytes: AI-Enabled Platform for Target ID, and Drug Discovery and Toxicity (e.g., Cancer Chemo & HIV ARTs) | NIH | National Institute of Mental Health | 2023 to 2025 | $2,798,182 | September 1, 2023 | August 31, 2026 | PRICE, JEFFREY H. | reporter.nih.gov |
| Understanding Hirschsprung disease using hPSC-derived models of the enteric nervous system | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,781,801 | September 15, 2025 | September 14, 2029 | FATTAHI, FARANAK | reporter.nih.gov |
| Defining the role of MafA in islet beta cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,772,028 | July 29, 2011 | May 31, 2027 | STEIN, ROLAND W | reporter.nih.gov |
| Exploring the role of ATP1A3 mutations in sudden unexplained death in epilepsy | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,764,922 | August 22, 2022 | June 30, 2027 | LANDSTROM, ANDREW P. | reporter.nih.gov |
| Computational and Experimental Modeling of Cardiomyocyte Proliferation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,757,722 | January 1, 2022 | December 31, 2026 | SAUCERMAN, JEFFREY J. | reporter.nih.gov |
| Identification, Quantification, and Functional Characterization of Transporters in Human Placenta, Developing Gut and Fetal Brain | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,755,586 | August 11, 2023 | June 30, 2028 | WANG, JOANNE | reporter.nih.gov |
| Benzodiazepine mediated mechanisms of transcriptional semi-quiescence in discrete myeloid populations | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,741,871 | September 15, 2022 | June 30, 2027 | GASKILL, PETER JESSE | reporter.nih.gov |
| Targeting off-the-shelf iPSC-derived natural killer cells against solid tumors | NIH | National Cancer Institute | 2023 to 2025 | $2,739,146 | August 1, 2023 | July 31, 2030 | MILLER, JEFFREY S. | reporter.nih.gov |
| Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,737,027 | May 1, 2012 | March 31, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,725,938 | February 4, 2021 | December 31, 2026 | MAVES, LISA | reporter.nih.gov |
| Functional Characterization of ABCA3 Genomic Variants | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,725,575 | February 15, 2020 | June 30, 2030 | WAMBACH, JENNIFER | reporter.nih.gov |
| In Vitro Human Tissue-Engineered Blood Vessel Disease Model of Progeria | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,720,700 | August 1, 2017 | April 30, 2027 | TRUSKEY, GEORGE A | reporter.nih.gov |
| Innovative therapeutic approaches to address excitotoxic CNS/neuronal damage in opioid-neuroHIV comorbidity | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,714,944 | August 15, 2022 | May 31, 2027 | HAUSER, KURT F | reporter.nih.gov |
| Metabolic and Hormonal Mechanisms of VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,707,906 | April 15, 2019 | August 31, 2029 | ZULOAGA, KRISTEN LEANNE | reporter.nih.gov |
| Establishment of a Human Microphysiological System to Elucidate Cellular Mechanisms Underlying Vulnerability to AD | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,683,965 | May 1, 2025 | April 30, 2028 | YOUNG-PEARSE, TRACY L | reporter.nih.gov |
| Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large Mammals | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,675,195 | August 9, 2022 | June 30, 2027 | ZHU, WUQIANG | reporter.nih.gov |
| Pathomechanisms of SCN3A-related neurodevelopmental disorder | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,674,943 | December 1, 2020 | November 30, 2026 | GOLDBERG, ETHAN M | reporter.nih.gov |
| Mechanisms and therapeutic implications of human clonal hematopoiesis (CH) mutations | NIH | National Cancer Institute | 2022 to 2025 | $2,657,718 | June 15, 2022 | May 31, 2027 | PAPAPETROU, EIRINI | reporter.nih.gov |
| Modeling human trophoblast-NK cell interactions in term and preterm birth | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,640,730 | April 1, 2021 | January 31, 2027 | PARAST, MANA M | reporter.nih.gov |
| Engineering High-Fidelity Human Cochlear Organoids | NIH | National Institute on Deafness and Other Communication Disorders | 2022 to 2025 | $2,639,492 | July 1, 2022 | June 30, 2027 | HASHINO, ERI | reporter.nih.gov |
| Stress and Human Stem/Progenitor Cells: Biobehavioral Mechanisms | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,635,227 | August 15, 2022 | June 30, 2027 | WADHWA, PATHIK D | reporter.nih.gov |
| A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human Cerebellum | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,630,611 | April 15, 2022 | March 31, 2027 | MILLEN, KATHLEEN JOYCE | reporter.nih.gov |
| Identification and characterization of mCpH binding proteins in neurons | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,629,388 | August 5, 2022 | July 31, 2027 | ZHU, HENG | reporter.nih.gov |
| Disease Mechanisms of Pontocerebellar Hypoplasia Type 10 | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,628,742 | July 1, 2021 | March 17, 2026 | SCHAFFER, ASHLEIGH E | reporter.nih.gov |
| Characterizing and Understanding Variation in Gene Regulatory Mechanisms Within and Between Species | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,610,282 | June 1, 2019 | May 31, 2029 | GILAD, YOAV | reporter.nih.gov |
| Marfan Aortic Embryologic Origin Influences Aneurysm Formation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,603,051 | April 1, 2016 | March 31, 2027 | FISCHBEIN, MICHAEL PETER | reporter.nih.gov |
| Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle loss | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,591,324 | March 1, 2021 | February 28, 2027 | SHIN, SU RYON | reporter.nih.gov |
| Development of a stem-cell derived thymic cell therapy to treat patients with athymia | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,586,728 | April 15, 2022 | January 31, 2027 | LIM, BING | reporter.nih.gov |
| Small Molecule Drug Discovery for CLN3 and CLN6 Disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,584,107 | September 20, 2021 | June 30, 2027 | TRIPPIER, PAUL | reporter.nih.gov |
| Assembly and characterization of human cortico-striatal neural networks | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,570,801 | August 1, 2021 | May 31, 2027 | SHCHEGLOVITOV, OLEKSANDR | reporter.nih.gov |
| Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase Toolbox | NIH | National Cancer Institute | 2022 to 2025 | $2,568,438 | July 1, 2022 | June 30, 2027 | HOSUR, VISHNU | reporter.nih.gov |
| Modeling Normal and Abnormal Trophoblasts | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,565,353 | September 25, 2018 | March 31, 2028 | SCHULZ, LAURA CLAMON | reporter.nih.gov |
| Impact of mutational order on molecular mechanisms of oncogenesis | NIH | National Cancer Institute | 2022 to 2025 | $2,563,938 | May 10, 2022 | February 28, 2027 | PAPAPETROU, EIRINI | reporter.nih.gov |
| Mechanistic analysis and allellic genome editing of iPSC-derived dominant LCA model | NIH | National Eye Institute | 2021 to 2025 | $2,545,050 | January 1, 2021 | November 30, 2025 | ULLIAN, ERIK M | reporter.nih.gov |
| Pathogenic Alterations of the 3D Epigenetic Landscape in Dystrophin-Deficient Skeletal Muscles and Reversal by Dystrophin Re-Expression | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $2,541,743 | August 1, 2009 | May 31, 2027 | PURI, PIER LORENZO | reporter.nih.gov |
| Elucidating endolysosomal trafficking dysregulation induced by APOE4 in human astrocytes | NIH | National Institute on Aging | 2023 to 2025 | $2,529,608 | April 1, 2023 | March 31, 2028 | TCW, JULIA | reporter.nih.gov |
| Mitochondrial defects in the retinal pigment epithelium and the CFH risk allele for age-related macular degeneration | NIH | National Eye Institute | 2022 to 2025 | $2,526,222 | April 1, 2018 | June 30, 2026 | FERRINGTON, DEBORAH ANN | reporter.nih.gov |
| Molecular mechanisms of aging and accelerated aging in the human brain | NIH | National Institute on Aging | 2023 to 2025 | $2,525,941 | September 15, 2023 | May 31, 2028 | MAVRIKAKI, MARIA | reporter.nih.gov |
| Investigating physiologic and pathophysiologic connections between the Parkinson's disease protein alpha-synuclein and RNA binding proteins | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,493,768 | August 1, 2023 | July 31, 2028 | KHURANA, VIKRAM | reporter.nih.gov |
| Ultra-High-Throughput Plate Reader for Drug Discovery Using All-Optical Electrophysiology | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,492,936 | February 17, 2025 | August 31, 2025 | LU, YANG | reporter.nih.gov |
| Molecular pathogenesis of blastomycosis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,491,942 | January 1, 1995 | May 31, 2027 | KLEIN, BRUCE STEVEN | reporter.nih.gov |
| A clear view of encephalitis: a single cell approach to determine the basis of flaviviral pathogenesis in the central nervous system | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,486,737 | January 21, 2022 | December 31, 2026 | RICE, CHARLES M | reporter.nih.gov |
| The role of BCL11B in T lineage fate during human thymopoiesis and pluripotent stem cell differentiation | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,483,404 | July 1, 2023 | June 30, 2028 | CROOKS, GAY M | reporter.nih.gov |
| Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration | NIH | National Institute on Aging | 2023 to 2025 | $2,474,500 | March 1, 2023 | February 29, 2028 | KUCHROO, VIJAY K. | reporter.nih.gov |
| The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,474,168 | August 1, 2015 | April 30, 2027 | MAZZULLI, JOSEPH R | reporter.nih.gov |
| An integrated human stem cell model for elucidating myocardial-endocardial interactions in cardiac development and disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,460,707 | February 15, 2021 | January 31, 2027 | ZHAO, MINGTAO | reporter.nih.gov |
| Elucidating ECM Signaling in Cardiac Organoids with Machine Learning and Single-cell Multiomics | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,451,978 | May 9, 2022 | April 30, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Neuronal senescence and inflammation in Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $2,440,018 | April 1, 2021 | March 31, 2026 | GAGE, FRED H | reporter.nih.gov |
| Functional long noncoding RNAs in neural development | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,437,149 | July 1, 2022 | June 30, 2027 | LIM, DANIEL A | reporter.nih.gov |
| Gene-Environment interactions in Autism | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $2,424,952 | January 20, 2022 | November 30, 2026 | CORCES, VICTOR G. | reporter.nih.gov |
| Lacritin Regulation of Homeostasis and Ocular Surface Health | NIH | National Eye Institute | 2021 to 2025 | $2,424,560 | September 1, 2021 | July 31, 2026 | LAURIE, GORDON WILLIAM | reporter.nih.gov |
| Investigating neurodevelopmental toxicity of perfluoroalkyl acids and their derivatives in human brain organoids models | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $2,419,460 | February 7, 2022 | November 30, 2026 | IAKOUCHEVA, LILIA M | reporter.nih.gov |
| Immunoevasive Engineered Living Blood Vessels | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2025 | $2,412,484 | August 5, 2022 | April 30, 2027 | CHAIKOF, ELLIOT | reporter.nih.gov |
| Desmosomes in cardiomyocyte homeostasis and disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,408,446 | December 15, 2022 | November 30, 2026 | PU, WILLIAM TSWENCHING | reporter.nih.gov |
| Mechanisms of Methylmercury Induced Neuronal Toxicity | NIH | National Institute of Environmental Health Sciences | 2022 to 2025 | $2,400,687 | March 1, 1996 | November 30, 2026 | ASCHNER, MICHAEL | reporter.nih.gov |
| Genetic Variants in Craniofacial Dystonias | NIH | National Institute of Dental & Craniofacial Research | 2022 to 2025 | $2,396,510 | September 1, 2022 | May 31, 2027 | SHARMA, NUTAN | reporter.nih.gov |
| Modeling HIV and methamphetamine-induced neuroinflammation in cerebral organoids | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,395,254 | September 1, 2022 | July 31, 2027 | SPEARMAN, PAUL W. | reporter.nih.gov |
| Effects of 16p11.2 copy number variation on neuronal development and pathology | NIH | National Institute of Mental Health | 2023 to 2025 | $2,394,048 | March 10, 2023 | February 29, 2028 | SAHIN, MUSTAFA | reporter.nih.gov |
| Mechanism of STING-mediated Neuropathology in Niemann-Pick Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,392,989 | August 1, 2021 | June 30, 2026 | YAN, NAN | reporter.nih.gov |
| IBIS-iPSC: Organoid modeling of cortical surface area hyperexpansion in autism spectrum disorder | NIH | National Institute of Mental Health | 2023 to 2025 | $2,389,134 | April 1, 2023 | January 31, 2028 | STEIN, JASON LOUIS | reporter.nih.gov |
| From intra to intercellular regulatory networks that define cell type identity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,381,600 | August 1, 2017 | July 31, 2027 | CAHAN, PATRICK | reporter.nih.gov |
| Neddylation and mitophagy in cardiac aging | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,381,119 | April 1, 2022 | March 31, 2027 | SUN, NUO | reporter.nih.gov |
| Small molecule therapeutic for calcific aortic valve disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,378,349 | August 1, 2023 | May 31, 2027 | SRIVASTAVA, DEEPAK | reporter.nih.gov |
| Human Isogenic Organoid Models of Genetic Forms of Autism to Identify Convergent and Divergent Pathomechanisms in Autism | NIH | National Institute of Mental Health | 2023 to 2025 | $2,362,709 | August 7, 2023 | May 31, 2028 | YEO, EUGENE WEI-MING | reporter.nih.gov |
| Regulation of pancreatic islet cell fate | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,361,366 | August 1, 2009 | July 31, 2027 | SUSSEL, LORI | reporter.nih.gov |
| Trillion cell culture to fuel organ biofabrication | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,361,000 | September 1, 2022 | August 31, 2027 | SKYLAR-SCOTT, MARK A. | reporter.nih.gov |
| STRA6 and Ocular Vitamin A Homeostasis | NIH | National Eye Institute | 2021 to 2025 | $2,359,309 | August 1, 2018 | August 31, 2027 | VON LINTIG, JOHANNES FRIEDRICH | reporter.nih.gov |
| Variant-to-gene mapping for brain related traits and disorders | NIH | National Human Genome Research Institute | 2021 to 2025 | $2,358,463 | September 10, 2021 | June 30, 2027 | CHESI, ALESSANDRA | reporter.nih.gov |
| 3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,352,214 | September 2, 2021 | June 30, 2026 | PARR, ANN M | reporter.nih.gov |
| Understanding the variation of induced β-cell differentiation. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,351,360 | July 1, 2022 | June 30, 2027 | LI, YAN | reporter.nih.gov |
| Macrophages and attenuation of inflammation resolution in APOL1 nephropathy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,348,020 | May 20, 2022 | March 31, 2027 | KAPITSINOU, PINELOPI P. | reporter.nih.gov |
| Developing a platform for human somatic cell rejuvenation, expansion and genetic engineering using synthetic RNA molecules | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,346,523 | May 1, 2021 | April 30, 2027 | KOGUT, IGOR | reporter.nih.gov |
| Mechanisms controlling human microglia gene expression | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,343,798 | May 15, 2016 | August 31, 2026 | GLASS, CHRISTOPHER K | reporter.nih.gov |
| Mechanistic studies of the genetic contribution of desmoplakin to pulmonary fibrosis in alveolar type 2 cells | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,340,458 | August 15, 2023 | July 31, 2027 | WILSON, ANDREW A | reporter.nih.gov |
| Multi-Tissue Craniofacial Engineering using 3D-BMP9-Notch-Synergized Graphene Citrate Composite Scaffolds | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,334,479 | April 1, 2021 | January 31, 2027 | REID, RUSSELL R. | reporter.nih.gov |
| ABCB5-positive stem cells for LSCD therapy | NIH | National Eye Institute | 2023 to 2025 | $2,325,074 | June 1, 2016 | May 31, 2028 | FRANK, MARKUS H. | reporter.nih.gov |
| Dynamic ECM-Mimicking Biomaterials for Ischemia Treatment | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,323,983 | December 15, 2021 | November 30, 2026 | ZOLDAN, JANETA | reporter.nih.gov |
| Cell Fate Regulation in Esophageal Progenitor Cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,322,436 | April 1, 2022 | March 31, 2027 | QUE, JIANWEN | reporter.nih.gov |
| High-throughput Phenotyping of iPSC-derived Airway Epithelium by Multiscale Machine Learning Microscopy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,320,786 | April 1, 2023 | February 28, 2027 | LEE, KWONMOO | reporter.nih.gov |
| Axonal transport and chemotherapy induced peripheral neuropathy | NIH | National Cancer Institute | 2022 to 2025 | $2,319,802 | April 1, 2016 | June 30, 2027 | SEGAL, ROSALIND A. | reporter.nih.gov |
| The Mitochondrion-STING Axis in An Early Childhood Onset Neurodegenerative Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,319,156 | September 15, 2021 | June 30, 2026 | YAN, NAN | reporter.nih.gov |
| Multiomics and Functional Characterization Establish Druggable Targets for PVC-Driven Idiopathic VF | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,317,590 | July 1, 2023 | June 30, 2027 | ECKHARDT, LEE LOCHBAUM | reporter.nih.gov |
| The impact of loss of function DNA sequence variants in the human protocadherin gene cluster on neural circuit assembly. | NIH | National Institute of Mental Health | 2023 to 2025 | $2,312,266 | July 1, 2023 | April 30, 2026 | MANIATIS, THOMAS P | reporter.nih.gov |
| Identifying pathogenic mechanisms underlying PACS1 Syndrome: implications for neural development | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,309,371 | August 5, 2022 | July 31, 2027 | GUEMEZ GAMBOA, ALICIA DIONE | reporter.nih.gov |
| Next generation calcium channel modulators | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,309,179 | December 20, 2019 | November 30, 2029 | DICK, IVY E | reporter.nih.gov |
| A cross-species preclinical platform to enhance the translation of new medicines | NIH | National Center for Advancing Translational Sciences | 2023 to 2025 | $2,306,784 | December 1, 2023 | November 30, 2026 | GEISSE, NICHOLAS ANDREW | reporter.nih.gov |
| Neural Stem Cell-derived EVs for Improving Aged Brain Function | NIH | National Institute on Aging | 2022 to 2025 | $2,306,114 | August 1, 2022 | April 30, 2027 | SHETTY, ASHOK K | reporter.nih.gov |
| High-throughput Functional Analysis of Autism Risk Genes | NIH | National Institute of Mental Health | 2021 to 2025 | $2,292,590 | March 1, 2018 | June 30, 2029 | HOFFMAN, ELLEN J | reporter.nih.gov |
| Investigating the Contribution of ALS/FTD-Associated Mutations in the NEK1 Kinase to Disease Pathophysiology | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,276,048 | July 15, 2023 | April 30, 2028 | KISKINIS, EVANGELOS | reporter.nih.gov |
| Metabolic dysfunction from ECM remodeling in diseases of human RPE | NIH | National Eye Institute | 2022 to 2025 | $2,274,411 | September 1, 2022 | June 30, 2027 | CHAO, JENNIFER RAYMING | reporter.nih.gov |
| Neurodevelopmental defects of the thalamocortical pathway as a convergent feature of psychiatric disorders | NIH | National Institute of Mental Health | 2023 to 2025 | $2,271,274 | May 1, 2023 | January 31, 2028 | NOWAKOWSKI, TOMASZ | reporter.nih.gov |
| Determining the optimal ion and fractionation scheme for the treatment of GBM in a comprehensive human organoid model | NIH | National Cancer Institute | 2021 to 2025 | $2,268,156 | March 1, 2021 | February 28, 2026 | GROSSHANS, DAVID R | reporter.nih.gov |
| Delineating the role of TIMP3 in macular degeneration | NIH | National Eye Institute | 2021 to 2025 | $2,268,028 | September 30, 2017 | May 31, 2027 | SINGH, RUCHIRA | reporter.nih.gov |
| Tapeworm stem cells as drivers of regeneration and reproduction | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,265,000 | March 5, 2021 | February 28, 2027 | ROZARIO, TANIA | reporter.nih.gov |
| Determining Potential Mechanisms of Worse Outcomes in Black HCM Patients | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,260,466 | August 10, 2023 | May 31, 2028 | CRESCI, SHARON | reporter.nih.gov |
| Trisomy 21 Model Atlas | NIH | Office of the Director, National Institutes of Health | 2023 to 2025 | $2,259,564 | September 19, 2023 | August 31, 2027 | GALBRAITH, MATTHEW D | reporter.nih.gov |
| The selective advantage of mismatch repair loss in colonic stem cells | NIH | National Cancer Institute | 2021 to 2025 | $2,253,508 | April 1, 2021 | March 31, 2027 | HEINEN, CHRISTOPHER D. | reporter.nih.gov |
| Unraveling the pathogenesis of familial dilated cardiomyopathy towards precision medicine | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,249,910 | July 1, 2018 | January 31, 2027 | KARAKIKES, IOANNIS | reporter.nih.gov |
| Enhancer RNAs in brain gene regulation and Alzheimer's disease | NIH | National Institute on Aging | 2023 to 2025 | $2,244,810 | May 1, 2023 | February 29, 2028 | LI, WENBO | reporter.nih.gov |
| The role of CELF2 and its genetic variants in Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $2,244,593 | February 1, 2021 | January 31, 2027 | CHEN, LIZHEN | reporter.nih.gov |
| Does biocompatibility contribute to transfusion-related adverse effects? | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,232,912 | January 15, 2018 | November 30, 2028 | POSNACK, NIKKI GILLUM | reporter.nih.gov |
| An electrophysiology platform that enables robust, scalable and long-term intracellular recording of cardiomyocytes | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,230,525 | July 1, 2022 | June 30, 2026 | CUI, BIANXIAO | reporter.nih.gov |
| Oxylipin Signaling in Congenital Heart Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,228,649 | January 1, 2021 | November 30, 2026 | AGUIRRE, AITOR | reporter.nih.gov |
| Mechanisms by which the ketone body β-hydroxybutyrate counteracts tau pathogenesis | NIH | National Institute on Aging | 2022 to 2025 | $2,223,061 | May 1, 2022 | February 28, 2027 | CHEN, XU | reporter.nih.gov |
| Molecular mechanisms of selective vulnerability of neurons to tauopathy | NIH | National Institute on Aging | 2023 to 2025 | $2,218,446 | June 1, 2023 | February 29, 2028 | KAMPMANN, MARTIN | reporter.nih.gov |
| Mechanisms of right ventricle adaptation to pulmonary hypertension | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,213,677 | September 1, 2019 | June 30, 2028 | LAHM, TIM | reporter.nih.gov |
| Transcriptomic and Circuitry Aberrations in Alzheimer’s Disease | NIH | National Institute on Aging | 2023 to 2025 | $2,209,375 | December 1, 2022 | November 30, 2027 | YAN, ZHEN | reporter.nih.gov |
| Cellular consequences and convergent biology of schizophrenia-associated rare variants in the GPC cohort | NIH | National Institute of Mental Health | 2025 | $2,209,242 | August 1, 2022 | May 31, 2027 | MULLE, JENNIFER GLADYS | reporter.nih.gov |
| Engineering the Stem Cell Microenvironment for Lymphatic Regeneration | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,205,356 | July 1, 2021 | May 31, 2027 | HANJAYA-PUTRA, DONNY | reporter.nih.gov |
| The Impact of hiPSC-Derived Microglia in Human Brain Development in Health and Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,201,423 | August 1, 2021 | July 31, 2026 | MUOTRI, ALYSSON R. | reporter.nih.gov |
| Ex-vivo bioengineered technology to unravel dysfunction due to non-alcoholic steatohepatitis (NASH) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,201,102 | July 1, 2023 | April 30, 2027 | WERTHEIM, JASON A | reporter.nih.gov |
| Montreal-Boston Collaborative GRC | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,199,265 | September 30, 2002 | June 30, 2027 | RIOUX, JOHN D. | reporter.nih.gov |
| Strategies to Enhance Engineered Heart Tissue Based Myocardial Repair | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,196,794 | January 1, 2023 | November 30, 2026 | ZHU, WUQIANG | reporter.nih.gov |
| Unraveling the Mechanisms of Neurodegeneration in TBCK Encephaloneuronopathy | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,193,534 | September 18, 2023 | June 30, 2028 | ORTIZ-GONZALEZ, XILMA R | reporter.nih.gov |
| Kinase Dysfunction in Autism and Neurodevelopmental Disorders | NIH | National Institute of Mental Health | 2023 to 2025 | $2,191,861 | March 15, 2023 | February 29, 2028 | YADAV, SMITA | reporter.nih.gov |
| Develop age-relevant glial cellular models using human directly reprogrammed cells | NIH | National Institute on Aging | 2021 to 2025 | $2,191,200 | September 30, 2021 | May 31, 2027 | SHI, YANHONG | reporter.nih.gov |
| Virtual systemic identification of drug targets of obesity candidate genes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $2,191,090 | April 1, 2023 | January 31, 2027 | LU, YINGCHANG | reporter.nih.gov |
| Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency | NIH | National Institute of Mental Health | 2023 to 2025 | $2,188,057 | August 1, 2023 | May 31, 2028 | KARN, JONATHAN | reporter.nih.gov |
| Investigation of a neuromesendodermal progenitor population in the posterior avian endoderm | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,183,686 | August 1, 2021 | May 31, 2027 | NERURKAR, NANDAN L | reporter.nih.gov |
| Assessing the effects of peripheral immune activation on the NVU following TBI using a vascularized and perfused human blood/BBB model | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,181,059 | September 15, 2021 | August 31, 2026 | AGALLIU, DRITAN | reporter.nih.gov |
| Genetic Approach to Therapy for DFNA9 | NIH | National Institute on Deafness and Other Communication Disorders | 2023 to 2025 | $2,180,163 | April 20, 2023 | March 31, 2028 | MORTON, CYNTHIA CASSON | reporter.nih.gov |
| Deciphering a Novel LncRNA-mediated Lipid Droplet Transport System in Human Heart | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,179,206 | August 1, 2022 | July 31, 2026 | YANG, LEI | reporter.nih.gov |
| Systematic Identification and Phenotypic Characterization of causal genetic variants in Rare Disease-Associated Birth Defects | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,179,104 | December 21, 2022 | November 30, 2027 | YOUNGER, SCOTT T | reporter.nih.gov |
| Premature aging disorders, metabolites, and atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,173,716 | December 15, 2022 | November 30, 2026 | ABE, JUN-ICHI | reporter.nih.gov |
| Role of ATAD3A in Lysosomal Homeostasis and Neurogenesis | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,172,201 | September 1, 2021 | August 31, 2027 | YOON, WAN HEE | reporter.nih.gov |
| Engineering Human Heart Tissues with Polyploid Cardiomyocytes | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,171,741 | May 1, 2022 | April 30, 2027 | BURSAC, NENAD | reporter.nih.gov |
| The role N-terminal acetylation in dilated cardiomyopathy and associated arrhythmia | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,170,056 | August 3, 2023 | April 30, 2027 | BEZZERIDES, VASSILIOS JAMES | reporter.nih.gov |
| Genetic underpinnings of craniofacial disorders explored with spatial sequencing | NIH | National Institute of Dental & Craniofacial Research | 2023 to 2025 | $2,169,288 | August 1, 2023 | May 31, 2028 | RUOHOLA-BAKER, HANNELE | reporter.nih.gov |
| Impaired VLDL secretion in progression of NAFLD and NASH in mice and humans | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,167,149 | July 16, 2019 | June 30, 2028 | DAVIDSON, NICHOLAS O. | reporter.nih.gov |
| Rewiring the Injured Brain with GABA Progenitors | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,163,757 | February 15, 2016 | March 31, 2027 | HUNT, ROBERT F | reporter.nih.gov |
| Expression of recombinant Fc receptors by engineered NK cells to enhance cancer cell killing | NIH | National Cancer Institute | 2021 to 2025 | $2,162,801 | January 1, 2016 | March 31, 2027 | WALCHECK, BRUCE K | reporter.nih.gov |
| Deciphering the Endothelial Cell-Cardiomyocyte Crosstalk in LMNA Cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,153,289 | September 15, 2021 | March 31, 2026 | SAYED, NAZISH | reporter.nih.gov |
| Viral subversion of intercellular coupling during myocarditis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,151,273 | July 1, 2022 | June 30, 2027 | SMYTH, JAMES WILLIAM | reporter.nih.gov |
| Human/Animal Brain Chimera in drugs of abuse and HIV | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,144,306 | August 15, 2022 | May 31, 2027 | AL-HARTHI, LENA | reporter.nih.gov |
| Vascular Regeneration with Direct Reprogramming and Engineering Strategies | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,143,183 | August 1, 2022 | July 31, 2026 | YOON, YOUNG-SUP | reporter.nih.gov |
| Establishing and reversing the functional consequences of Titin truncation mutations | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,142,683 | July 1, 2022 | June 30, 2027 | HINSON, JOHN TRAVIS | reporter.nih.gov |
| Elucidating the Origin of Sudden Cardiac Death in Dilated Cardiomyopathy: from Phenotype Predictors to Therapeutic Targets | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,141,973 | April 5, 2023 | February 29, 2028 | MESTRONI, LUISA | reporter.nih.gov |
| Interplay between mitophagy and substrate utilization in heart failure progression | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,125,860 | December 6, 2021 | November 30, 2026 | SUN, NUO | reporter.nih.gov |
| Identifying Cis-Regulatory Variants, Genes, and Regulatory Networks Underlying QT Interval Variation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,119,646 | May 1, 2022 | April 30, 2027 | KAPOOR, ASHISH | reporter.nih.gov |
| Regulation of synaptic plasticity by BDNF-endocannabinoid interactions | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,110,192 | December 1, 2019 | November 30, 2026 | LEVINE, ERIC S | reporter.nih.gov |
| Extracellular matrix regulation of cellular crosstalk in cardiac fibrosis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,106,837 | April 1, 2023 | March 31, 2027 | MCNALLY, ELIZABETH M | reporter.nih.gov |
| Missense Variants in Myosin Binding Protein C that Cause Hypertrophic Cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,100,429 | September 1, 2023 | August 31, 2027 | DAY, SHARLENE M | reporter.nih.gov |
| Functional characterization of schizophrenia rare variants using genetically engineered human iPSCs | NIH | National Institute of Mental Health | 2023 to 2025 | $2,099,952 | January 1, 2023 | November 30, 2027 | LI, PAN | reporter.nih.gov |
| Skeletal Muscle Regeneration from Pluripotent Stem Cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,097,940 | June 1, 2021 | May 31, 2027 | PERLINGEIRO, RITA C. R. | reporter.nih.gov |
| Cerebral organoid and IPSC derived microglia: Modeling of HIV and methamphetamine co-morbidity | NIH | National Institute on Drug Abuse | 2022 to 2025 | $2,096,889 | September 1, 2022 | July 31, 2027 | YELAMANCHILI, SOWMYA | reporter.nih.gov |
| Uncovering the functional diversification mechanisms of transcription factor isoforms involved in stem cell differentiation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,096,585 | August 1, 2021 | May 31, 2027 | SHEYNKMAN, GLORIA | reporter.nih.gov |
| A physiologically relevant pre-clinical drug screening platform for Alzheimer's Disease and Traumatic Brain Injury with integrated stretchable microelectrodes | NIH | National Institute on Aging | 2022 to 2025 | $2,090,923 | September 30, 2022 | November 30, 2026 | GRAUDEJUS, OLIVER | reporter.nih.gov |
| Epigenetic mechanisms of gene regulation in nephron progenitor cell proliferation and differentiation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,088,471 | July 1, 2021 | June 30, 2027 | RAUCHMAN, MICHAEL I | reporter.nih.gov |
| DEFINING REGULATORY ROLES FOR HISTONE H3 METHYLATION IN DEVELOPMENT | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,087,570 | July 15, 2021 | March 31, 2027 | BRUMBAUGH, JUSTIN | reporter.nih.gov |
| Understanding and targeting molecular and cellular events responsible for pulmonary arteriovenous malformation development, growth and regression | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,087,563 | September 1, 2023 | August 31, 2027 | SPIEKERKOETTER, EDDA FRAUKE | reporter.nih.gov |
| High-Throughput NMJ Assay for Botox Potency Screening | NIH | National Center for Advancing Translational Sciences | 2023 to 2025 | $2,086,960 | August 1, 2023 | January 31, 2027 | GEISSE, NICHOLAS ANDREW | reporter.nih.gov |
| Role of NOD2 Variants in Eosinophilic Esophagitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,086,360 | September 11, 2025 | September 10, 2029 | SHODA, TETSUO | reporter.nih.gov |
| Towards Novel Therapies for CACNA1A Neurological Disorders | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,079,389 | March 15, 2022 | February 28, 2027 | COLECRAFT, HENRY M. | reporter.nih.gov |
| Assembly of Novel Gene Editing Particles to Understand Genome Surgery in Patient-Derived Cells | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,078,314 | August 19, 2016 | May 31, 2026 | SAHA, KRISHANU | reporter.nih.gov |
| Assessment of the Complement Pathway in a RPE/choroid Tissue Chip | NIH | National Eye Institute | 2024 to 2025 | $2,066,956 | September 1, 2024 | April 30, 2028 | ROHRER, BAERBEL | reporter.nih.gov |
| Human iPSC-Based Personalized Cell Therapy of PD | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,062,628 | July 1, 2023 | April 30, 2028 | KIM, KWANG-SOO | reporter.nih.gov |
| Sensitization of developing sensory neurons after incision | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,061,836 | June 1, 2019 | February 28, 2029 | JANKOWSKI, MICHAEL P | reporter.nih.gov |
| 5-methylcytosine oxidation in development and disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $2,060,740 | May 15, 2021 | December 31, 2026 | PFEIFER, GERD P | reporter.nih.gov |
| Novel Strategies for Understanding and Treating Fibrous Dysplasia | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $2,059,414 | July 1, 2023 | April 30, 2028 | HSIAO, EDWARD C | reporter.nih.gov |
| Dissecting and Targeting RB1-Mutant Osteosarcoma | NIH | National Cancer Institute | 2021 to 2025 | $2,054,629 | March 1, 2021 | February 28, 2027 | LEE, DUNG-FANG | reporter.nih.gov |
| BIOMATERIALS FOR STEM CELL-DERIVED BETA CELL TRANSPLANTATION | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,054,178 | September 17, 2021 | July 31, 2026 | GARCIA, ANDRES J | reporter.nih.gov |
| The Genetics of the Neuromuscular Junction: Mechanisms and Disease Models | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,053,330 | August 1, 2025 | May 31, 2027 | BURGESS, ROBERT W. | reporter.nih.gov |
| Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's Disease | NIH | National Institute on Aging | 2023 to 2025 | $2,051,423 | May 15, 2023 | March 31, 2028 | DUAN, JUBAO | reporter.nih.gov |
| Mechanisms and determinants of dynamic gene regulation during development and cellular differentiation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,050,000 | September 21, 2021 | July 31, 2026 | POTT, SEBASTIAN | reporter.nih.gov |
| Dissect Human Primordial Germ Cell Development Using Stem Cell Models | NIH | National Institute of General Medical Sciences | 2025 | $2,043,430 | September 1, 2025 | August 31, 2029 | ZHENG, YI | reporter.nih.gov |
| Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical Injuries | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,031,527 | July 1, 2021 | June 30, 2027 | CHEN, HAN-CHIAO ISAAC | reporter.nih.gov |
| Molecular Biomarkers in pathogenesis of Lymphangioleiomyomatosis (LAM) | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,022,093 | September 10, 2023 | June 30, 2027 | D'ARMIENTO, JEANINE M | reporter.nih.gov |
| A Drug Discovery Platform to Prioritize Development of Natural Product Neuromodulators for Treating Cognitive Impairment | NIH | National Institute on Aging | 2024 to 2025 | $2,019,940 | December 1, 2023 | March 31, 2027 | BROWN, JEFFREY M. | reporter.nih.gov |
| Programmable Off-the-Shelf Dendritic Cells as an Immunotherapy Discovery Platform | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,008,699 | September 1, 2021 | August 31, 2026 | TRUONG, DAVID MINH | reporter.nih.gov |
| Regulation of HTT-mediated DNA damage repair and chromatin remodeling Complexes | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,008,557 | September 20, 2023 | August 31, 2028 | SARKAR, PARTHA S | reporter.nih.gov |
| A Gene-Network Discovery Approach to Structural Brain Disorders | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,006,305 | September 15, 2023 | May 31, 2028 | LOUVI, ANGELIKI | reporter.nih.gov |
| Microheart muscle based discovery and development of inotropic compounds | NIH | National Center for Advancing Translational Sciences | 2022 to 2025 | $2,003,255 | August 15, 2022 | June 30, 2027 | WALL, SAMUEL | reporter.nih.gov |
| Alcohol Use Disorder: Acamprosate Pharmacometabolomics-informed Pharmacogenomics | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $1,997,071 | September 1, 2024 | June 30, 2029 | WEINSHILBOUM, RICHARD M. | reporter.nih.gov |
| Study of AR transcriptional network in stem cell model of SBMA | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,988,689 | April 1, 2021 | March 31, 2027 | MIRANDA, HELEN C | reporter.nih.gov |
| Mechanisms and targeting of aberrant Gas activation in myeloid neoplasms | NIH | National Cancer Institute | 2023 to 2025 | $1,986,303 | April 1, 2023 | March 31, 2028 | PAPAPETROU, EIRINI | reporter.nih.gov |
| Uncovering Molecular Targets for Arrhythmogenic Cardiomyopathy Therapeutics | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,975,000 | April 1, 2022 | March 31, 2027 | SHEIKH, FARAH | reporter.nih.gov |
| Mechanisms of Kidney Diseases Associated With APOL1 Variation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,973,997 | February 2, 2023 | December 31, 2026 | SEDOR, JOHN R. | reporter.nih.gov |
| An assay suite featuring hiPSC-derived neurons and support cells, to test toxicants and industrial chemicals for developmental neurotoxic effects | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $1,972,828 | June 19, 2024 | May 31, 2026 | GORDON, KARA L | reporter.nih.gov |
| Autophagon: an Autophagy-Functionalizing Gene Therapy Tool for Neurodegenerative Diseases | NIH | National Institute on Aging | 2023 to 2025 | $1,972,119 | March 15, 2022 | December 31, 2026 | YAKOUB, ABRAAM M. | reporter.nih.gov |
| REGULATORS OF CALCINEURIN PATHWAYS AS DIAGNOSTIC AND THERAPEUTIC TARGETS FOR NEPHROTIC SYNDROME | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,970,219 | February 1, 2023 | December 31, 2026 | GBADEGESIN, RASHEED ADEBAYO | reporter.nih.gov |
| Optimizing Models of Non-Coding Genetic Risk in Age-Related Macular Degeneration | NIH | National Eye Institute | 2022 to 2025 | $1,969,000 | March 1, 2022 | February 28, 2026 | CHERRY, TIMOTHY JOEL | reporter.nih.gov |
| Roles for uniquely human enhancers in brain development and WNT signaling | NIH | National Institute of Mental Health | 2023 to 2025 | $1,966,795 | March 9, 2023 | December 31, 2027 | SILVER, DEBRA L. | reporter.nih.gov |
| Choriocapillaris Protection and Replacement in AMD | NIH | National Eye Institute | 2021 to 2025 | $1,966,287 | August 1, 2014 | December 31, 2027 | MULLINS, ROBERT FOSTER | reporter.nih.gov |
| Assembling the Genetic Architecture of X-linked Dystonia Parkinsonism | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,965,121 | September 1, 2017 | December 31, 2028 | TALKOWSKI, MICHAEL E | reporter.nih.gov |
| Novel Therapeutics for Timothy Syndrome and Related Cardiac Channelopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,964,096 | September 1, 2023 | May 31, 2027 | YAZAWA, MASAYUKI | reporter.nih.gov |
| An integrated MPS platform with "virtual humans" for chemical toxicity testing | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $1,961,064 | August 22, 2024 | July 31, 2027 | VUKASINOVIC, JELENA | reporter.nih.gov |
| Trophoblast progenitor heterogeneity and function in normal and Trisomy 21-affected placentae | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,959,382 | September 20, 2023 | June 30, 2028 | PARAST, MANA M | reporter.nih.gov |
| Investigating the role of lipid metabolism in protein aggregation and neurodegenerative disease progression | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,957,052 | December 1, 2020 | November 30, 2026 | DAVIS, MARIE YNEZ | reporter.nih.gov |
| Vascular Regeneration with Human Pluripotent Stem Cell-derived Vascular Cells and Engineering Approaches | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,956,185 | January 15, 2022 | December 31, 2025 | YOON, YOUNG-SUP | reporter.nih.gov |
| Biopsychosocial determinants of pediatric-onset chronic musculoskeletal pain | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2025 | $1,955,201 | September 19, 2025 | July 31, 2030 | KASHIKAR-ZUCK, SUSMITA | reporter.nih.gov |
| Biomaterial Platforms to Model the Role of Mechanical Overload in MYBPC3-Linked Hypertrophic Cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $1,955,125 | September 1, 2021 | August 31, 2027 | HUEBSCH, NATHANIEL | reporter.nih.gov |
| Shared mechanisms of astrocyte maturation in development and glioblastoma | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,949,981 | September 30, 2021 | June 30, 2027 | SPANGLE, JENNIFER MARIE | reporter.nih.gov |
| Cell Intrinsic and Extrinsic Factors Driving Maturation in Human PSC-derived Neurons | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,946,321 | August 1, 2023 | July 31, 2028 | STUDER, LORENZ P. | reporter.nih.gov |
| Role of SUMOylation in Mitochondrial/Synaptic Axis Dysfunction Induced by Abnormal Tau in FTD | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,941,311 | September 19, 2023 | August 31, 2028 | QUINZII, CATARINA M. | reporter.nih.gov |
| Elucidating the role of Adaptor Protein complex-4 in regulating axonal autophagic and lysosomal pathways | NIH | National Institute on Aging | 2022 to 2025 | $1,940,113 | September 15, 2022 | May 31, 2027 | GOWRISHANKAR, SWETHA | reporter.nih.gov |
| Molecular mechanisms of triplet repeat instability in Huntington's disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,938,300 | July 1, 2021 | June 30, 2027 | PLUCIENNIK, ANNA | reporter.nih.gov |
| Early developmental mechanisms of Rett Syndrome | NIH | National Institute of Mental Health | 2021 to 2025 | $1,936,688 | December 1, 2009 | January 31, 2027 | SUR, MRIGANKA | reporter.nih.gov |
| Individualized medicine to predict and prevent chemotherapy-related heart failure | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,934,221 | July 1, 2023 | November 30, 2026 | NORTON, NADINE | reporter.nih.gov |
| Genomic analysis of the Multiplex, Autozygous Populations in Cerebral Palsy (MAP CP) cohort: a focused approach to a complex disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,933,393 | February 1, 2023 | January 31, 2028 | KRUER, MICHAEL C | reporter.nih.gov |
| Developing a renewable and dissectible human liver for the study of HBV/HCV infection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,932,000 | August 18, 2022 | July 31, 2027 | WU, XIANFANG | reporter.nih.gov |
| Dissecting the role of DNA Ligase 1 in Huntington's disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,927,817 | July 25, 2023 | June 30, 2028 | WHEELER, VANESSA C | reporter.nih.gov |
| Molecular Genetic Analysis of TORC1 and TORC2 Signaling in Neuronal Maintenance | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,926,179 | December 15, 2013 | November 30, 2029 | LU, BINGWEI | reporter.nih.gov |
| Mitochondrial iron export therapy for doxorubicin-induced cardiotoxicity | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,921,021 | January 1, 2023 | December 31, 2026 | KIM, JONGHAN | reporter.nih.gov |
| Exploring the pathophysiology and treatment of LCHADD retinopathy | NIH | National Eye Institute | 2021 to 2025 | $1,913,450 | September 1, 2021 | July 31, 2026 | GILLINGHAM, MELANIE B | reporter.nih.gov |
| Epicardial regulation of cardiomyocyte function via modulation of extracellular signals: toward a model of human muscle pump function | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,911,866 | July 1, 2022 | June 30, 2027 | OGLE, BRENDA M | reporter.nih.gov |
| Mechanistic insight into genome stability pathways | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,907,859 | June 1, 2021 | May 31, 2026 | BIELINSKY, ANJA-KATRIN | reporter.nih.gov |
| PAX6-induced adult neurogenesis | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,907,530 | July 1, 2022 | June 30, 2027 | ZHANG, CHUN-LI | reporter.nih.gov |
| Label-free single-cell imaging for quality control of cardiomyocyte biomanufacturing | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,900,815 | April 1, 2023 | March 31, 2027 | SKALA, MELISSA CAROLINE | reporter.nih.gov |
| Arrhythmia Mechanisms Modulated by Intercalated Disc Extracellular Nanodomains | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,895,385 | April 1, 2023 | February 28, 2027 | POELZING, STEVEN | reporter.nih.gov |
| Leveraging GWAS Findings to Map Variants and Identify Novel Effector Genes for Alcohol-Related Traits | NIH | National Institute on Alcohol Abuse and Alcoholism | 2023 to 2025 | $1,894,888 | May 1, 2023 | January 31, 2028 | KRANZLER, HENRY RICHARD | reporter.nih.gov |
| Establishing and Mimicking Patterning Mechanisms in the Distal Nephron Tubule and Kidney Organoid | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,891,016 | August 1, 2023 | June 30, 2028 | LINDSTROM, NILS OLOF | reporter.nih.gov |
| Molecular Principles Governing Mitochondrial and Peroxisomal Remodeling as Drivers of Cell Fate and Identity | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,889,532 | August 1, 2018 | July 31, 2029 | GAMA, VIVIAN | reporter.nih.gov |
| An Integrated Drug Discovery Platform for Neurodevelopmental Disorders Using Standardized Self-Organizing Human Cerebroids | NIH | National Institute of Mental Health | 2024 to 2025 | $1,879,800 | May 1, 2024 | April 30, 2027 | ETOC, FRED | reporter.nih.gov |
| MR Imaging of Bioscaffold-Induced Neural Progenitor Migration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,877,043 | July 1, 2021 | June 30, 2027 | MODO, MICHEL M. | reporter.nih.gov |
| Altered inflammatory response associated with acquired DNMT3A mutations | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,875,949 | May 1, 2021 | April 30, 2027 | BYUN, MINJI | reporter.nih.gov |
| Measuring and modeling the dynamics ofpatterning in human stem cells | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,875,174 | January 11, 2019 | July 31, 2027 | RAMANATHAN, SHARAD | reporter.nih.gov |
| Gene regulatory networks in early lung epithelial cell fate decisions | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,865,248 | February 1, 2023 | January 31, 2027 | IKONOMOU, LAERTIS | reporter.nih.gov |
| Establishment of a First-in-Class Biocompatible and Efficient Cryopreservation Technology Platform for the Next Generation of Cell-Based Therapeutics in Regenerative Medicine and Drug Discovery | NIH | Office of the Director, National Institutes of Health | 2024 to 2025 | $1,863,241 | September 15, 2024 | August 31, 2026 | HAN, XU | reporter.nih.gov |
| Deciphering the role of Lmod2 in cardiac muscle and in dilated cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,862,717 | April 1, 2015 | May 31, 2029 | GREGORIO, CAROL C | reporter.nih.gov |
| Cellular and Genetic Defects in Keratoconus | NIH | National Eye Institute | 2023 to 2025 | $1,859,473 | June 10, 2016 | January 31, 2027 | CHAKRAVARTI, SHUKTI | reporter.nih.gov |
| Mechanisms of epithelial alterations in diabetic cornea | NIH | National Eye Institute | 2022 to 2025 | $1,857,956 | August 1, 2001 | June 30, 2027 | LJUBIMOV, ALEXANDER V | reporter.nih.gov |
| Allele-specific inactivation for dominant negative NEFL Mutations | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,855,975 | August 15, 2021 | June 30, 2027 | JUDGE, LUKE M | reporter.nih.gov |
| Regulation of human tendon development and regeneration | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,844,584 | April 15, 2023 | May 31, 2028 | HUANG, ALICE H | reporter.nih.gov |
| Elucidating the etiology of SPAST-based Hereditary Spastic Paraplegia | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,843,784 | December 15, 2020 | November 30, 2026 | QIANG, LIANG | reporter.nih.gov |
| Michigan Hepatotoxicity Clinical Research Network Renewal | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,834,456 | September 30, 2003 | July 31, 2028 | FONTANA, ROBERT J | reporter.nih.gov |
| Epigenetics-Based Autism Treatment with Animal Models and Human Stem Cells | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,833,202 | February 15, 2023 | January 31, 2028 | YAN, ZHEN | reporter.nih.gov |
| Loss-of-Function Analyses of SETD1A in Human Neural Models | NIH | National Institute of Mental Health | 2023 to 2025 | $1,830,368 | July 1, 2021 | April 30, 2026 | PANG, ZHIPING P. | reporter.nih.gov |
| Pathogenesis and motor neuron degeneration of a novel disease associated with a P158A mutation in NAMPT | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,826,814 | February 15, 2022 | December 31, 2026 | DING, SHINGHUA | reporter.nih.gov |
| Chloride Homeostasis in Lysosomal Function and Parkinson's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,813,734 | July 1, 2022 | April 30, 2028 | MAO, ZIXU | reporter.nih.gov |
| Mechanisms of nuclear morphology regulation | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,809,946 | January 1, 2020 | December 31, 2028 | LEVY, DANIEL LEON | reporter.nih.gov |
| Establishing an In Vitro Embryotoxicity Risk Classification System Based on Human Cardiac Organoid Model | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $1,809,852 | April 1, 2020 | November 30, 2026 | MA, ZHEN | reporter.nih.gov |
| Aberrant protein S-nitrosylation mediates Gene-Environment Interactions in AD/ADRD | NIH | National Institute on Aging | 2024 to 2025 | $1,809,238 | September 15, 2024 | June 30, 2029 | LIPTON, STUART A | reporter.nih.gov |
| Crosstalk between innate-immunity human microglia and adaptive-immunity Tregs in Alzheimer's disease | NIH | National Institute on Aging | 2022 to 2025 | $1,807,050 | September 1, 2022 | May 31, 2027 | LIPTON, STUART A | reporter.nih.gov |
| Compromised LDH activity causes motor deficits and hastens ALS progression | NIH | National Institute on Aging | 2023 to 2025 | $1,805,312 | July 1, 1996 | January 31, 2028 | MILBRANDT, JEFFREY D | reporter.nih.gov |
| Lead optimization of a novel cyclic aryl-indole efflux pump inhibitor (EPI) series in combination with levofloxacin against Pseudomonas aeruginosa | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,799,789 | May 1, 2024 | April 30, 2027 | PARHI, AJIT K | reporter.nih.gov |
| Defining and perturbing gene regulatory dynamics in the developing human brain | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,794,496 | April 1, 2023 | March 31, 2028 | GREENLEAF, WILLIAM JAMES | reporter.nih.gov |
| Regulation and impact of shortened TDP43 isoforms in FTD and ALS | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,794,354 | December 1, 2019 | August 31, 2029 | BARMADA, SAMI | reporter.nih.gov |
| Sex-specific Molecular Profiling to Understand Pathology and Identify Causal Genes and Drug Targets for Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $1,793,985 | September 30, 2021 | August 31, 2026 | SUNG, YUNJU | reporter.nih.gov |
| Characterization of schizophrenia liability genes in models of human microglial synaptic pruning | NIH | National Institute of Mental Health | 2023 to 2025 | $1,793,419 | July 12, 2023 | March 31, 2028 | SHERIDAN, STEVEN D | reporter.nih.gov |
| Reverse Tissue-Manufacturing of the Multicellular Sinoatrial Node Organoids | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,792,225 | April 1, 2023 | March 31, 2027 | PARK, SUNG JIN | reporter.nih.gov |
| Understanding Schizophrenia Risk Mechanisms Via Multimodal Analysis of Patient-derived Neurons and 3D Cortical Organoids and Correlation with Clinical and Cognitive Phenotypes | NIH | National Institute of Mental Health | 2024 to 2025 | $1,786,771 | August 7, 2024 | April 30, 2026 | MAHER, BRADY J | reporter.nih.gov |
| Pharmacologic Lysosomal Flux Activators to Ameliorate Alzheimer's Disease and Related Dementias | NIH | National Institute on Aging | 2024 to 2025 | $1,778,822 | September 1, 2021 | August 31, 2026 | KELLY, JEFFERY W | reporter.nih.gov |
| Mechanisms and Treatment of Hajdu Cheney Syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,778,744 | July 1, 2021 | May 31, 2027 | CANALIS, ERNESTO | reporter.nih.gov |
| Studying the Role of the Microenvironment on Differentiation and Maturation of Beta Cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,778,223 | July 1, 2017 | May 31, 2027 | MILLMAN, JEFFREY ROBERT | reporter.nih.gov |
| Engineering induction and assembly of human kidney tissue | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,772,787 | April 1, 2022 | March 31, 2027 | HUGHES, ALEX | reporter.nih.gov |
| Rescuing SYNGAP1 haploinsufficiency by redirecting alternative splicing | NIH | National Institute of Mental Health | 2023 to 2025 | $1,771,111 | April 1, 2023 | March 31, 2028 | ZHANG, XIAOCHANG | reporter.nih.gov |
| Lasting Impacts: Dynamic, Fully Natural Bioprinted 3D Human Neurovascular Biomimetic Model to Study Traumatic Brain Injury Pathophysiology | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,766,629 | September 15, 2021 | December 31, 2026 | MOYA, MONICA LIZET | reporter.nih.gov |
| Discovery of apoE4 modulators for Alzheimer’s disease therapy | NIH | National Institute on Aging | 2022 to 2025 | $1,763,127 | September 30, 2022 | May 31, 2027 | LI, YONGHE | reporter.nih.gov |
| Alcohol-induced cardiac injury and repair in human induced pluripotent stem cell model | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $1,760,250 | April 20, 2021 | March 31, 2027 | XU, CHUNHUI | reporter.nih.gov |
| Patterning Genes in Retinal Development | NIH | National Eye Institute | 2021 to 2025 | $1,759,668 | June 1, 1998 | May 31, 2029 | STENKAMP, DEBORAH L | reporter.nih.gov |
| Reverse Engineering the Extracellular Neighborhood to Support the Functional Tissue Unit: A Use Case to Restore Ovarian Function | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $1,753,326 | August 24, 2022 | July 31, 2026 | LARONDA, MONICA M | reporter.nih.gov |
| Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity | NIH | National Cancer Institute | 2023 to 2025 | $1,751,883 | January 1, 2023 | December 31, 2027 | STAFF, NATHAN P | reporter.nih.gov |
| Spatiotemporal signaling and trafficking of the mu-opioid receptor | NIH | National Institute on Drug Abuse | 2023 to 2025 | $1,750,312 | July 15, 2022 | May 31, 2027 | HUTTENHAIN, RUTH | reporter.nih.gov |
| Pluripotent stem cell-derived organoid model of human gonad development, functions, and disorders | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,746,338 | September 18, 2023 | August 31, 2027 | JORDAN, PHILIP W | reporter.nih.gov |
| Mechanisms of impaired ESCRT-III nuclear surveillance in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,736,889 | August 1, 2023 | May 31, 2028 | COYNE, ALYSSA | reporter.nih.gov |
| Deep mutational scanning of MYH7 in genome-edited cardiomyocytes | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,735,014 | August 5, 2024 | April 30, 2029 | YANG, KAI-CHUN DANIEL | reporter.nih.gov |
| Homeotic hotspot in the human genome for eye and brain disease | NIH | National Eye Institute | 2022 to 2025 | $1,730,360 | August 1, 2022 | June 30, 2027 | GLASER, THOMAS M. | reporter.nih.gov |
| Promoting Protein Trafficking with 4-phenylbutyrate to Treat Genetic Epilepsy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,720,363 | March 1, 2022 | February 28, 2027 | KANG, JING-QIONG | reporter.nih.gov |
| Optically Promoting Cardiac Maturation Using Engineered Peptides | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,713,467 | September 1, 2023 | June 30, 2027 | ARDONA, HERDELINE ANN MALLARI | reporter.nih.gov |
| AI-designed mini-proteins as drivers of pancreatic islet production from pluripotent stem cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $1,712,270 | September 25, 2025 | July 31, 2030 | CIRULLI, VINCENZINO | reporter.nih.gov |
| Human endothelial cell regulation of ossification | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,712,166 | August 10, 2022 | May 31, 2027 | MELERO-MARTIN, JUAN M | reporter.nih.gov |
| The Function of the Cytoplasmic tRNA Repertoire in the Cellular and Molecular Homeostasis of the Mammalian Brain | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,709,379 | January 15, 2022 | December 31, 2026 | ACKERMAN, SUSAN L | reporter.nih.gov |
| hiPSC Modeling of Restrictive Cardiomyopathy for Drug Testing | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,704,626 | July 1, 2023 | June 30, 2027 | MERCOLA, MARK | reporter.nih.gov |
| Dissect formative pluripotency using cultured pluripotent stem cells | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,702,655 | July 22, 2021 | May 31, 2026 | WU, JUN | reporter.nih.gov |
| Elucidating pathogenic mechanisms in STRADA-related brain malformation and epilepsy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,696,274 | August 15, 2022 | June 30, 2027 | DANG, LOUIS TUONG CHINH | reporter.nih.gov |
| Role of N-terminal acetylation in alpha synuclein stability, function, and therapeutic targeting in synucleinopathies | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,693,159 | September 13, 2024 | July 31, 2029 | RHOADES, ELIZABETH | reporter.nih.gov |
| STK25 phosphorylates PRKAR1A to regulate PKA signaling | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,687,751 | August 1, 2023 | June 30, 2028 | FINE, BARRY M. | reporter.nih.gov |
| Investigations of proteome turnover kinetics under cellular differentiation | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,686,775 | September 17, 2022 | July 31, 2027 | LAU, EDWARD | reporter.nih.gov |
| Microphysiological modeling of Endometriosis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,681,646 | September 25, 2023 | June 30, 2027 | KIM, JI-YONG JULIE | reporter.nih.gov |
| Novel Inhibitors for Temporal Modulation of T-Lymphocytes during Chronic Heart Failure | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,680,264 | July 1, 2023 | June 30, 2027 | BANSAL, SHYAM SUNDER | reporter.nih.gov |
| Mechanism-inspired Strategies to Prevent Pathogenic Late Na Current in Cardiac Arrhythmias | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,678,112 | February 17, 2023 | November 30, 2026 | JOHNY, MANU BEN | reporter.nih.gov |
| Modulation of heart function by Muscle LIM protein-mediated mechanotransduction | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,675,000 | July 1, 2022 | June 30, 2026 | QYANG, YIBING | reporter.nih.gov |
| Articular Cartilage Tissue Engineering with Human Pluripotent Stem Cells | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,673,298 | April 1, 2021 | March 31, 2027 | NAKAYAMA, NAOKI | reporter.nih.gov |
| Mechanisms of sex-biased risk and resiliency in aneurysm and dissection | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,670,000 | September 16, 2022 | August 31, 2026 | PARKER, SARAH J | reporter.nih.gov |
| Characterization of AD-related endolysosomal dysfunction in human neural cells | NIH | National Institute on Aging | 2024 to 2025 | $1,667,545 | May 1, 2024 | April 30, 2029 | YOUNG, JESSICA ELAINE | reporter.nih.gov |
| Dissecting genetic determinants of epigenetic instability in pluripotent stem cells | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,667,501 | April 15, 2022 | February 28, 2026 | STADTFELD, MATTHIAS | reporter.nih.gov |
| Developing Splicing-Targeted Therapeutic Strategies for Neurological Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,667,400 | August 1, 2022 | April 30, 2026 | MORINI, ELISABETTA | reporter.nih.gov |
| Transcriptomics-based identification of cell type specific host genes and gene networks perturbed by HSV-1 in cerebral organoids. | NIH | National Institute on Aging | 2024 to 2025 | $1,658,235 | July 15, 2024 | April 30, 2029 | LIM, TENG-TING ELAINE | reporter.nih.gov |
| Examining the effect of cadmium metal exposure on Alzheimer's disease genetic alleles using herpes viral infected cerebral organoids | NIH | National Institute on Aging | 2024 to 2025 | $1,658,220 | September 15, 2024 | June 30, 2029 | CHAN, YING LEONG | reporter.nih.gov |
| Developmental Timing During Cortical Development | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,657,822 | May 1, 2022 | April 30, 2027 | NOWAKOWSKI, TOMASZ | reporter.nih.gov |
| Targeting Arc to Improve Cognitive Deficits in Psychotic Disorders | NIH | National Institute of Mental Health | 2024 to 2025 | $1,651,680 | July 8, 2024 | February 28, 2029 | KARMACHARYA, RAKESH | reporter.nih.gov |
| 3D Bioprinted Human Model of Duchenne Muscular Dystrophy (DMD) Cardiomyopathy to Study Disease Progression with Imposed Force and Precise Gene Editing | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,651,448 | July 1, 2023 | April 30, 2028 | KAMDAR, FORUM D | reporter.nih.gov |
| Deconvoluting the Ewing sarcoma genetic program using ancestry-informed human iPSC modeling | NIH | National Cancer Institute | 2023 to 2025 | $1,644,656 | April 7, 2023 | March 31, 2028 | WEBBER, BEAU RICHARD | reporter.nih.gov |
| SOX17/RUNX1 Axis Regulates Endothelial Cell Fate in the Pathogenesis of Pulmonary Arterial Hypertension | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,640,000 | August 25, 2022 | June 30, 2027 | LIANG, OLIN D. | reporter.nih.gov |
| Damage-Free, Ultrasonic Cell Isolation from Retinal Pigment Epithelium (RPE) Monolayers | NIH | National Eye Institute | 2023 to 2025 | $1,636,690 | August 1, 2023 | February 28, 2027 | KIM, EUN SOK | reporter.nih.gov |
| Therapeutic evaluation of targeting Tau Tubulin kinase-1 in Alzheimer’s disease | NIH | National Institute on Aging | 2023 to 2025 | $1,632,295 | February 1, 2023 | January 31, 2028 | IKEZU, SEIKO | reporter.nih.gov |
| Using guided differentiation to predict cancer treatment related cardiotoxicity | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,631,020 | July 1, 2024 | May 31, 2028 | GILAD, YOAV | reporter.nih.gov |
| A precision therapy approach to red cell transfusion for sickle cell disease | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,629,998 | May 1, 2024 | April 30, 2029 | CHOU, STELLA T | reporter.nih.gov |
| Molecular dissection of Hematopoietic Stem Cell specification triggered by inflammatory mediators | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,627,339 | February 1, 2022 | January 31, 2027 | ESPIN PALAZON, RAQUEL | reporter.nih.gov |
| Cell-Type Specific Vulnerability to Tauopathy and Its Prevention in Multiple Models | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,625,424 | February 1, 2021 | January 31, 2026 | SIGURDSSON, EINAR M | reporter.nih.gov |
| Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,615,000 | May 15, 2022 | April 30, 2027 | ALTAMIRANO, FRANCISCO | reporter.nih.gov |
| Mitochondrial Dysfunction Underlies the Integrated Stress Response Activation in Ponatinib-Induced Cardiotoxicity | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,614,431 | July 18, 2023 | June 30, 2028 | LEE, WON HEE | reporter.nih.gov |
| Modeling the impact of regulatory and splicing variants on cellular function in Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,611,377 | March 1, 2021 | February 28, 2027 | RAJ, TOWFIQUE | reporter.nih.gov |
| A mechanistic 3D AI-powered map of genetic chILD | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,605,000 | September 1, 2024 | August 31, 2029 | XU, YAN | reporter.nih.gov |
| Pericyte contribution to capillary remodeling in pulmonary arterial hypertension | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,604,206 | January 1, 2024 | December 31, 2027 | YUAN, KE | reporter.nih.gov |
| Identifying the molecular mechanisms of GEMIN5 mutations in a novel cerebellar ataxia syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,603,046 | September 15, 2023 | June 30, 2028 | PANDEY, UDAI B | reporter.nih.gov |
| Chemical Approaches to Understand O-GlcNAc Glycosylation and Its Roles in Neurodegeneration | NIH | National Institute on Aging | 2024 to 2025 | $1,602,138 | December 1, 2002 | April 30, 2029 | HSIEH-WILSON, LINDA C | reporter.nih.gov |
| APOE Genotype Mediated Effects on Alzheimer Disease Risk and Mechanisms | NIH | National Institute on Aging | 2024 to 2025 | $1,596,269 | September 15, 2024 | June 30, 2029 | FARRER, LINDSAY A. | reporter.nih.gov |
| Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,594,872 | September 30, 2016 | April 30, 2029 | ELLERBY, LISA M | reporter.nih.gov |
| Genetics-informed dissection of human brain cell-cell communication in Alzheimer's disease progression | NIH | National Institute on Aging | 2024 to 2025 | $1,594,515 | August 1, 2024 | April 30, 2029 | LI, BINGSHAN | reporter.nih.gov |
| Inhibition of hepatic (V)LDL production by a novel antagonist of carboxyl esterase 1 | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,594,367 | September 1, 2023 | August 31, 2027 | DUNCAN, STEPHEN A | reporter.nih.gov |
| Investigation of Cardiac Arrhythmias in TANGO2 Disorder | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,588,776 | August 9, 2024 | May 31, 2029 | MIYAKE, CHRISTINA YUMI | reporter.nih.gov |
| Cellular Pathophysiology of Neuronal Na/K-ATPase Dysfunction | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,587,968 | June 15, 2022 | April 30, 2027 | GEORGE, ALFRED L. | reporter.nih.gov |
| Targeting Dystroglycanopathies using Pluripotent-derived Myogenic Progenitors | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,583,772 | February 10, 2023 | November 30, 2027 | PERLINGEIRO, RITA C. R. | reporter.nih.gov |
| Digital Twins from the Atom to the Rhythm | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,582,062 | July 1, 2024 | May 31, 2028 | CLANCY, COLLEEN E | reporter.nih.gov |
| A Multifaceted Approach to Study Tissue and Cell Type Specific Molecular Mechanisms of the Host Response to Acute/Chronic Viral Infection | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,580,127 | September 10, 2017 | July 31, 2028 | THOMAS, EMMANUEL | reporter.nih.gov |
| Mechanisms of myocardial regeneration mediated by Nkx2.5 in zebrafish | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,578,254 | April 1, 2023 | March 31, 2028 | TARGOFF, KIMARA L | reporter.nih.gov |
| Role of retinoic acid signaling in fovea development | NIH | National Eye Institute | 2022 to 2025 | $1,577,955 | January 1, 2022 | December 31, 2026 | DA SILVA, SUSANA ISABEL M M A | reporter.nih.gov |
| Chemical Genetic Dissection of SWI/SNF Chromatin Remodeling Complex Functions in Cerebral Cortex Development | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,577,226 | April 1, 2023 | March 31, 2028 | VIERBUCHEN, THOMAS S | reporter.nih.gov |
| Role of OPA1 in Retinal Ganglion Cell Differentiation and the Pathogenesis of Dominant Optic Atrophy | NIH | National Eye Institute | 2022 to 2025 | $1,576,094 | September 30, 2022 | August 31, 2027 | ZACK, DONALD J. | reporter.nih.gov |
| Neurodevelopmental mechanisms in 17q12 CNV disorders and autism | NIH | National Institute of Mental Health | 2024 to 2025 | $1,575,774 | September 1, 2024 | March 31, 2029 | MORROW, ERIC M | reporter.nih.gov |
| Unraveling the role of endothelium in chemotherapy-induced cardiotoxicity | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,574,936 | January 1, 2022 | March 31, 2026 | SAYED, NAZISH | reporter.nih.gov |
| Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE) | NIH | National Eye Institute | 2022 to 2025 | $1,574,000 | September 30, 2022 | August 31, 2026 | SKOWRONSKA-KRAWCZYK, DOROTA | reporter.nih.gov |
| Functional Analysis of Complement Variants in a Genotyped iPSC Epithelial Cell Model System | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,563,098 | December 4, 2023 | October 31, 2028 | STAMBOLIAN, DWIGHT EDWARD | reporter.nih.gov |
| Systemic Transplantation of MyoPAXon: IND Enabling Studies for the Treatment of DMD | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,559,533 | September 25, 2023 | July 31, 2027 | KYBA, MICHAEL | reporter.nih.gov |
| Defining TBK1-associated autophagy networks in neurons | NIH | National Institute on Aging | 2024 to 2025 | $1,557,479 | August 15, 2024 | April 30, 2029 | MORDES, DANIEL ADAM | reporter.nih.gov |
| Age-equivalent neurons from MCI patients to investigate early determinants of AD | NIH | National Institute on Aging | 2024 to 2025 | $1,556,984 | August 15, 2024 | April 30, 2029 | MERTENS, JEROME S. | reporter.nih.gov |
| Mapping causal genetic processes in non-Mendelian pediatric rare disease | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,556,880 | September 16, 2022 | August 31, 2027 | SMAIL, CRAIG | reporter.nih.gov |
| A unique subpopulation of wild-type neurons recapitulating FAD phenotypes | NIH | National Institute on Aging | 2023 to 2025 | $1,556,307 | March 1, 2023 | November 30, 2027 | MAESAKO, MASATO | reporter.nih.gov |
| A Fully Patterned Human Neural Tube Model Using Microfluidics | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,554,627 | August 15, 2023 | May 31, 2028 | FU, JIANPING | reporter.nih.gov |
| Sonic Hedgehog Signaling in Neocortical Growth and Folding | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $1,554,342 | September 30, 2017 | December 31, 2028 | HAN, YOUNG-GOO | reporter.nih.gov |
| Cellular and genomic mechanisms of the impact of ethanol on human neural model | NIH | National Institute on Alcohol Abuse and Alcoholism | 2023 to 2025 | $1,552,427 | February 5, 2016 | March 31, 2027 | PANG, ZHIPING P. | reporter.nih.gov |
| Lymphatic Regeneration by Direct Cellular Reprogramming | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,552,332 | July 1, 2023 | June 30, 2027 | YOON, YOUNG-SUP | reporter.nih.gov |
| Evaluating the p-Tau inhibition and neuroprotective effects of sAPPalpha using brain permeable small molecules | NIH | National Institute on Aging | 2022 to 2025 | $1,552,200 | September 1, 2022 | May 31, 2027 | JOHN, VARGHESE | reporter.nih.gov |
| Characterization of Compartmentalized GPCR Signaling in Neurons | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,549,722 | June 15, 2022 | May 31, 2027 | TSVETANOVA, NIKOLETA GEORGIEVA | reporter.nih.gov |
| Molecular feedback between cell division cycle and differentiation in pluripotent stem cells | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,548,116 | September 1, 2022 | August 31, 2027 | SHARIATI, ALI | reporter.nih.gov |
| Multi-scale consequences of variants in the schizophrenia risk gene SETD1A in a population isolate. | NIH | National Institute of Mental Health | 2022 to 2025 | $1,545,000 | August 15, 2022 | May 31, 2027 | AMENT, SETH ABRAMS | reporter.nih.gov |
| A Next Generation Outer Retinal Microphysiological System | NIH | National Eye Institute | 2022 to 2025 | $1,545,000 | May 1, 2022 | April 30, 2026 | TUCKER, BUDD A | reporter.nih.gov |
| Bidirectional control of Chd2 haploinsufficiency | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,541,689 | January 1, 2023 | December 31, 2027 | HUNT, ROBERT F | reporter.nih.gov |
| iPSC-based Model to Study Frontotemporal Dementia Due to MAPT Mutation | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,540,579 | June 1, 2025 | May 31, 2027 | TEMPLE, SALLY | reporter.nih.gov |
| Elucidating the Pathomechanisms of APOE4 in Lewy Body Dementia | NIH | National Institute on Aging | 2024 to 2025 | $1,538,709 | July 1, 2024 | March 31, 2029 | ZHAO, NA | reporter.nih.gov |
| Mechanisms of Persistent Inflammasome Activation in Myeloid Cells | NIH | National Institute on Drug Abuse | 2024 to 2025 | $1,534,687 | September 30, 2024 | May 31, 2029 | GUMMULURU, SURYARAM | reporter.nih.gov |
| Mapping, programming, and correcting gene regulatory sequences for Alagille Syndrome | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,533,046 | December 15, 2023 | November 30, 2027 | ENGREITZ, JESSE M | reporter.nih.gov |
| Investigation of active kinome networks in Alzheimer's dementia. | NIH | National Institute on Aging | 2024 to 2025 | $1,529,808 | September 15, 2024 | May 31, 2029 | MCCULLUMSMITH, ROBERT E | reporter.nih.gov |
| hiPS cells derived skeletal muscle progenitors and their extracellular vesicles for treatment of sarcopenia | NIH | National Institute on Aging | 2022 to 2025 | $1,529,509 | January 1, 2021 | December 31, 2026 | XUAN, WANLING | reporter.nih.gov |
| Acquisition of an automated robotic culture system for organoid generation, maintenance, and phenotyping | NIH | Office of the Director, National Institutes of Health | 2025 | $1,521,607 | May 15, 2025 | May 14, 2027 | BIREY, FIKRI | reporter.nih.gov |
| Contribution of AD genetic risk and microglial BIN1 to tauopathy | NIH | National Institute on Aging | 2024 to 2025 | $1,519,523 | September 30, 2024 | June 30, 2029 | COUFAL, NICOLE GABRIELE | reporter.nih.gov |
| Targeting Proteostatic Mechanisms to Inhibit LRRK2-Mediated Neurodegeneration and Neuropathology | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,518,700 | April 30, 2024 | August 31, 2028 | HINIKER, ANNIE E | reporter.nih.gov |
| Nicotine and NLRP3 Inflammasome in HIV-1-Associated CNS Inflammation | NIH | National Institute on Drug Abuse | 2024 to 2025 | $1,517,460 | May 15, 2024 | February 28, 2029 | SWARTZ, TALIA H | reporter.nih.gov |
| PASK-regulated genes and proteins as therapeutic targets for ALS and FTD | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,516,783 | September 19, 2024 | July 31, 2029 | SCOLES, DANIEL R | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Indiana University Indianapolis | Indianapolis, IN | 14 | $94.5 million | 0 | $0 |
| Stanford University | Stanford, CA | 69 | $90.2 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 37 | $68.2 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 38 | $60.1 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 35 | $57.9 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 23 | $52.4 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 34 | $51.1 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 34 | $50.3 million | 0 | $0 |
| Duke University | Durham, NC | 18 | $48.7 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 7 | $43.9 million | 0 | $0 |
| Washington University | Saint Louis, MO | 27 | $40.8 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 26 | $37.8 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 29 | $36.4 million | 0 | $0 |
| Emory University | Atlanta, GA | 22 | $35.1 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 19 | $32.3 million | 0 | $0 |
| University of Washington | Seattle, WA | 24 | $32.1 million | 0 | $0 |
| Yale University | New Haven, CT | 21 | $32 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 6 | $30.9 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 20 | $29.5 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 14 | $28.5 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 17 | $28.3 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 17 | $27.8 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 14 | $27.6 million | 0 | $0 |
| Massachusetts Institute of Technology | Cambridge, MA | 9 | $25.3 million | 0 | $0 |
| The Emmes Company, LLC | Rockville, MD | 1 | $25.3 million | 0 | $0 |
| Sloan-Kettering Inst Can Research | New York, NY | 9 | $24.8 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 13 | $24.5 million | 0 | $0 |
| J. David Gladstone Institutes | San Francisco, CA | 12 | $22.9 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 19 | $21.9 million | 0 | $0 |
| Buck Institute for Research on Aging | Novato, CA | 3 | $21 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 12 | $20.8 million | 0 | $0 |
| Scripps Research Institute, the | La Jolla, CA | 10 | $19.9 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 15 | $19.8 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 24 | $18.1 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 14 | $17.2 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 7 | $15.5 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 17 | $15.1 million | 0 | $0 |
| University of Chicago | Chicago, IL | 10 | $14.9 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 10 | $14.6 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 11 | $13.9 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 10 | $13.1 million | 0 | $0 |
| University of Texas at San Antonio | San Antonio, TX | 2 | $12.5 million | 0 | $0 |
| Jackson Laboratory | Bar Harbor, ME | 3 | $12.3 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 10 | $12.3 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 11 | $11.7 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 10 | $11.6 million | 0 | $0 |
| Regenerative Research Foundation | Albany, NY | 3 | $11.5 million | 0 | $0 |
| Albert Einstein College of Medicine | Bronx, NY | 7 | $11.5 million | 0 | $0 |
| Brown University | Providence, RI | 6 | $11.4 million | 0 | $0 |
| Marine Biological Laboratory | Woods Hole, MA | 1 | $11.2 million | 0 | $0 |
| Coriell Institute for Medical Research | Camden, NJ | 1 | $10.7 million | 0 | $0 |
| University of Connecticut SCH of Med/dnt | Farmington, CT | 7 | $10.7 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 7 | $9.6 million | 0 | $0 |
| Mayo Clinic Jacksonville | Jacksonville, FL | 7 | $9.6 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 5 | $9.4 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 7 | $9.1 million | 0 | $0 |
| University of Rochester | Rochester, NY | 8 | $9 million | 0 | $0 |
| University of Nebraska Medical Center | Omaha, NE | 3 | $8.5 million | 0 | $0 |
| University of California at Davis | Davis, CA | 8 | $8.4 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 5 | $8.4 million | 0 | $0 |
| SUNY at Buffalo | Amherst, NY | 8 | $8.3 million | 0 | $0 |
| Ohio State University | Columbus, OH | 7 | $8.1 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 7 | $7.9 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 4 | $7.6 million | 0 | $0 |
| Fox Chase Chemical Diversity Center, INC | Doylestown, PA | 1 | $7.4 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 6 | $7.3 million | 0 | $0 |
| Seattle Children's Hospital | Seattle, WA | 3 | $7.3 million | 0 | $0 |
| Purdue University | West Lafayette, IN | 5 | $7.2 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 5 | $7.1 million | 0 | $0 |
| Rutgers University New Brunswick | New Brunswick, NJ | 1 | $6.9 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 3 | $6.8 million | 0 | $0 |
| Fred Hutchinson Cancer Center | Seattle, WA | 3 | $6.8 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 7 | $6.6 million | 0 | $0 |
| Texas A&m University Health Science CTR | College Station, TX | 3 | $6.6 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 7 | $6.5 million | 0 | $0 |
| University of Iowa | Iowa City, IA | 7 | $6.4 million | 0 | $0 |
| Drexel University | Philadelphia, PA | 6 | $6.3 million | 0 | $0 |
| Mayo Clinic Arizona | Scottsdale, AZ | 3 | $6.2 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 7 | $6 million | 0 | $0 |
| Endeavor Health Clinical Operations | Evanston, IL | 2 | $5.7 million | 0 | $0 |
| Medical University of South Carolina | Charleston, SC | 6 | $5.6 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 5 | $5.5 million | 0 | $0 |
| Harvard University | Cambridge, MA | 6 | $5.2 million | 0 | $0 |
| University of Missouri-Columbia | Columbia, MO | 3 | $5.1 million | 0 | $0 |
| Children's Mercy Hosp (kansas City, Mo) | Kansas City, MO | 3 | $5 million | 0 | $0 |
| University of TX MD Anderson Can CTR | Houston, TX | 4 | $5 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 2 | $4.9 million | 0 | $0 |
| The University of Texas Rio Grande Valley | Edinburg, TX | 1 | $4.9 million | 0 | $0 |
| Iowa State University | Ames, IA | 2 | $4.8 million | 0 | $0 |
| Vala Sciences, Inc. | San Diego, CA | 2 | $4.8 million | 0 | $0 |
| Broad Institute, Inc. | Cambridge, MA | 4 | $4.5 million | 0 | $0 |
| Curi Bio INC | Seattle, WA | 2 | $4.4 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 4 | $4.4 million | 0 | $0 |
| Syracuse University | Syracuse, NY | 3 | $4.4 million | 0 | $0 |
| University of South Florida | Tampa, FL | 5 | $4.3 million | 0 | $0 |
| Virginia Polytechnic Institute and State University | Blacksburg, VA | 3 | $4.3 million | 0 | $0 |
| ST. Joseph's Hospital and Medical Center | Phoenix, AZ | 2 | $4.3 million | 0 | $0 |
| Pennsylvania State Univ Hershey Med CTR | Hershey, PA | 4 | $4.1 million | 0 | $0 |
| Michigan State University | East Lansing, MI | 3 | $4.1 million | 0 | $0 |
| University of Colorado at Boulder | Boulder, CO | 3 | $4 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 1,241 | $741,372,519 | 0 | $0 |
| 2024 | 855 | $488,025,512 | 0 | $0 |
| 2023 | 554 | $370,706,540 | 0 | $0 |
| 2022 | 351 | $265,392,444 | 0 | $0 |
| 2021 | 197 | $155,048,372 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.