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Data / Research funding / Immunization

Immunization: 3,881 NIH awards ($9.4B) to 680 organizations

3,881 NIH awards ($9.4B) in the NIH spending category Immunization, to 680 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 3,881 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
NIAID HIV and Other Infectious Diseases Clinical Research Support Services (CRSS)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$417,904,831August 15, 2023August 14, 2024STROKES, BAMBRAreporter.nih.gov
HIV Vaccines Clinical Trials Network Leadership and Operations CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$244,071,463June 29, 2006November 30, 2027COREY, LAWRENCEreporter.nih.gov
HIV Prevention Trials Network Leadership and Operations CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$213,590,410June 1, 2006November 30, 2027COHEN, MYRON SCOTTreporter.nih.gov
HIV and Other Infectious Diseases Clinical Research Support Services (CRSS)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$198,645,463August 15, 2025August 14, 2026STOKES, BAMBRAreporter.nih.gov
HIV Vaccine Trials Network Laboratory CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$177,480,054June 29, 2006November 30, 2027MCELRATH, MARGARET JULIANAreporter.nih.gov
SDMC: HIV Vaccine Trials NetworkNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$156,744,802June 29, 2006November 30, 2027GILBERT, PETER B.reporter.nih.gov
CoVPN LOC Cross-Protocol Infrastructure Supplement for GY15 and GY16NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$156,469,927March 30, 2022March 31, 2022COREY, LAWRENCEreporter.nih.gov
Consortium for HIV/AIDS Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$145,502,241July 1, 2019June 30, 2026BURTON, DENNIS R.reporter.nih.gov
Induction of protective antibodies for HIV vaccine developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$143,048,158July 15, 2019June 30, 2026HAYNES, BARTON F.reporter.nih.gov
Consortium for Advancing Management and Prevention of Cancer in People with HIVNIHNational Cancer Institute2021 to 2025$106,635,299August 29, 2006August 31, 2030SPARANO, JOSEPH A.reporter.nih.gov
NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE: AVIAN INFLUENZA RESEARCHNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$91,354,067April 1, 2021January 14, 2027WEBBY, RICHARDreporter.nih.gov
IMPAACT Leadership GroupNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$77,468,129December 1, 2024November 30, 2027NACHMAN, SHARON Areporter.nih.gov
COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCHNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$72,825,966September 10, 2019September 24, 2026KRAMMER, FLORIANreporter.nih.gov
NIAID CLINICAL SITE MONITORINGNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$68,539,045February 1, 2023January 31, 2024SMITH, KIMBERLYreporter.nih.gov
Leadership Group for the Infectious Diseases Clinical Research Consortium (IDCRCLG)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$63,155,364December 5, 2019November 30, 2026STEPHENS, DAVID Sreporter.nih.gov
NIAID Centers of Excellence for Influenza Research and ResponseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$62,580,113April 1, 2021September 17, 2026GARCIA-SASTRE, ADOLFOreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$61,029,344September 30, 2019March 31, 2027URDAHL, KEVINreporter.nih.gov
CoVPN 5001 - A prospective study of acute immune responses to SARS-CoV-2 infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$57,987,348March 21, 2022March 31, 2022GILBERT, PETER B.reporter.nih.gov
HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals: LC 3NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$54,331,950March 18, 2022March 31, 2022MCELRATH, MARGARET JULIANAreporter.nih.gov
CIVIC: University of Georgia Center for Influenza Vaccine Research in High Risk PopulationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$53,879,677September 10, 2019September 9, 2026ROSS, TEDreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$52,452,735September 10, 2019September 9, 2026MOODY, TONYreporter.nih.gov
DAIDS Quality Assurance, Quality Control and Inspection Readiness Support ServicesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$51,529,857April 17, 2025April 16, 2026reporter.nih.gov
CEIRR: CORONAVIRUS RESEARCH ACTIVITIESNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$50,650,417April 1, 2021September 29, 2026HENSLEY, SCOTTreporter.nih.gov
Clinical Research Products Management Center (CRPMC)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$46,852,833June 16, 2025June 15, 2026REMGSAMAI-NHE, CARINAreporter.nih.gov
SUPPORT SERVICES OF THE HIV AIDS CLINICAL TRIAL NETWORKSNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$45,166,816November 30, 2022November 29, 2025DRIVER, BARBARAreporter.nih.gov
Implementing Vaccine and Treatment Evaluation Unit (VTEU) Clinical SiteNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$44,959,734August 13, 2025November 30, 2026KOTLOFF, KAREN L.reporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component B: Vaccine Manufacturing and Toxicology CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$44,296,051August 26, 2019March 13, 2028DENNY, THOMASreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$38,435,039September 30, 2019September 29, 2026FORTUNE, SARAHreporter.nih.gov
Vanderbilt Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$36,564,580December 11, 2019November 30, 2026CREECH, CLARENCE BUDDYreporter.nih.gov
Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$35,184,139August 1, 2021July 31, 2026COLER, RHEAreporter.nih.gov
Cancer Center Support Grant (CCSG)NIHNational Cancer Institute2021 to 2025$35,080,297April 1, 1997February 28, 2026ROBERTS, CHARLESreporter.nih.gov
Production of Aluminum Based AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$34,078,534September 20, 2017December 31, 2026MACK, FREDreporter.nih.gov
Pediatric Adolescent Virus Elimination (PAVE) Martin Delaney CollaboratoryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$30,092,882August 16, 2021April 30, 2027PERSAUD, DEBORAHreporter.nih.gov
DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$30,010,720May 2, 2019April 30, 2027WEBBY, RICHARD JOHNreporter.nih.gov
FOLLOW-UP AND EXTENDED FOLLOW-UP OF PARTICIPANTSNIHNational Cancer Institute2021 to 2025$29,487,084April 6, 2018September 15, 2026PORRAS, CAROLINAreporter.nih.gov
Task V15: Development of Assays and Reagents for mpox VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$28,751,383September 1, 2022April 30, 2026RUDGE, THOMASreporter.nih.gov
REACH: Research Enterprise to Advance a Cure for HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$27,533,114August 16, 2021April 30, 2027JONES, R. BRADreporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response (CEIRR): Avian Influenza Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$27,250,171April 1, 2021January 14, 2027LOWEN, ANICEreporter.nih.gov
B and T Cell Biology of Protection from and Eradication of SIV/SHIV InfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$26,314,793June 1, 2022May 31, 2027HUNTER, ERICreporter.nih.gov
Impact of the Initial Influenza Exposure on the Quality, Magnitude, Breadth, Potency and Durability of Influenza ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,789,202May 15, 2019April 30, 2027STAAT, MARY Areporter.nih.gov
University of North Carolina Global HIV Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,477,809February 1, 2007November 30, 2027ERON, JOSEPH Jreporter.nih.gov
I4C 2.0: Immunotherapy for CureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$23,329,181August 16, 2021April 30, 2027BAROUCH, DAN H.reporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$23,280,590August 1, 2021January 14, 2027PEKOSZ, ANDREWreporter.nih.gov
Vaccine and Treatment Evaluation UnitsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$22,981,366December 11, 2019November 30, 2026ROUPHAEL, NADINE GEORGESreporter.nih.gov
MANUFACTURE OF CLINICAL GRADE EPSTEIN-BARR VIRUS VACCINENIHNational Cancer Institute2023 to 2025$22,579,077September 22, 2025September 21, 2027reporter.nih.gov
SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimensNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$21,986,953September 2, 2022June 30, 2027WILLIAMS, WILTON Breporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,625,203April 1, 2021September 14, 2027TOMPKINS, S. MARKreporter.nih.gov
UZ-UCSF CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,624,239September 9, 2025November 30, 2027CHIRENJE, ZVAVAHERA MIKEreporter.nih.gov
UCLA AIDS Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,546,764February 1, 2007November 30, 2027LANDOVITZ, RAPHAEL Jreporter.nih.gov
Boston HIV CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,445,869January 15, 2007November 30, 2027KURITZKES, DANIEL R.reporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
New Mexico IDeA Networks of Biomedical Research Excellence (INBRE)NIHNational Institute of General Medical Sciences2021 to 2025$20,744,885September 30, 2001March 31, 2029LUSETTI, SHELLEYreporter.nih.gov
COVID-19: External Quality Assurance Program Oversight Laboratory (EQAPOL)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$20,632,183September 30, 2023September 29, 2024DENNY, THOMASreporter.nih.gov
Alzheimer's Prevention Initiative ADAD Colombia Trial ProgramNIHNational Institute on Aging2024 to 2025$20,406,409September 1, 2024August 31, 2029ALEXANDER, ROBERT Creporter.nih.gov
Vaccine and Treatment Evaluation Units (VTEU) 24-0003NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$19,949,752December 11, 2019November 30, 2026EL SAHLY, HANA Mreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component C: Clinical CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$19,720,676September 16, 2019September 15, 2026FRANKENFIELD, JILLreporter.nih.gov
ADJUVANT COMPARISON AND CHARACTERIZATIONNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$19,155,153September 1, 2022August 31, 2027PULENDRAN, BALIreporter.nih.gov
ADVANCED DEVELOPMENT OF A VACCINE FOR PANDEMIC AND PRE-EMERGENT CORONAVIRUSESNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$18,205,751September 19, 2022September 18, 2026SAUNDERS, KEVINreporter.nih.gov
Cancer Center Support Grant P30NIHNational Cancer Institute2021 to 2025$17,994,069July 1, 2002June 30, 2026LARA, PRIMO N.reporter.nih.gov
Immunologic strategies to prevent congenital cytomegalovirus transmission and disease in rhesus monkeysNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,214,484July 24, 2019May 31, 2029PERMAR, SALLIE R.reporter.nih.gov
Emory-CDC CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,972,899December 1, 2024November 30, 2027KELLEY, COLLEEN Freporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component C: Clinical CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,914,921September 16, 2019September 30, 2026BERES, WENDELLreporter.nih.gov
University of Pennsylvania HIV Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,198,927February 1, 2007November 30, 2027FRANK, IANreporter.nih.gov
DEVELOPMENT OF A VACCINE CANDIDATE FOR CORONAVIRUSESNIHNational Institute of Allergy and Infectious Diseases2023$15,898,493June 1, 2023May 31, 2026KRAMMER, FLORIANreporter.nih.gov
PERU Clinical Trial UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,506,525December 1, 2024November 30, 2027SANCHEZ, JORGE LUISreporter.nih.gov
Targeting Inflammation and Alloimmunity in Lung Transplant Recipients With ClazakizumabNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,471,597September 14, 2021June 30, 2028MADSEN, JOREN Creporter.nih.gov
NIAID Influenza Data Processing and Communication Center: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,386,477April 1, 2021March 31, 2026BOUR, STEPHANreporter.nih.gov
Immune signatures of vaccine responses in vulnerable populationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,275,325July 12, 2010April 30, 2028MONTGOMERY, RUTH Rreporter.nih.gov
University of Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,173,751December 11, 2019November 30, 2026WALD, ANNAreporter.nih.gov
FSH - an Aging Hormone?NIHNational Institute on Aging2021 to 2025$15,166,862February 1, 2019April 30, 2029ZAIDI, MONEreporter.nih.gov
A Phase-2b, Double-Blind, Randomized Controlled Trial to Evaluate the Activity and Safety of Inebilizumab in Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis and Assess Markers of DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$15,144,108September 15, 2021August 31, 2027CLARDY, STACEY LYNNreporter.nih.gov
PHRU-Setshaba Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,110,381December 1, 2024November 30, 2027GRAY, GLENDA Ereporter.nih.gov
Consolidated Basic Cancer Research ProgramNIHNational Cancer Institute2021 to 2025$14,936,465April 1, 1997February 28, 2026ALTIERI, DARIO Creporter.nih.gov
HIPC Data Coordinating CenterNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$14,760,228April 13, 2022March 31, 2027PETERS, BJOERNreporter.nih.gov
University of Rochester Vaccine and Treatment Evaluation Unit (VTEU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,263,529December 11, 2019November 30, 2026FALSEY, ANN Rreporter.nih.gov
Kaiser Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,173,633December 11, 2019November 30, 2026JACKSON, LISA Areporter.nih.gov
Simian Vaccine Evaluation Unit: Maintenance of Nonhuman PrimatesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,042,495April 1, 2020March 31, 2027AYE, PYONEreporter.nih.gov
Simian Vaccine Evaluation Unit: Maintenance of Nonhuman PrimatesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,765,907April 1, 2020March 31, 2027VILLINGER, FRANCOISreporter.nih.gov
HIV/AIDS Clinical Trials Units University of Cape Town CTU 2020 to 2027NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,518,599April 1, 2007November 30, 2027BEKKER, LINDA-GAILreporter.nih.gov
Protective immunity following dengue virus natural infections and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,429,941July 29, 2015July 31, 2030HARRIS, EVAreporter.nih.gov
Establishment of the New York University Vaccine and Treatment Evaluation Unit (NYU VTEU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,340,237April 10, 2020November 30, 2026MULLIGAN, MARK JOSEPHreporter.nih.gov
IND-enabling Studies in Support of First in Human Safety Studies of a Novel Anti-Nicotine Human Monoclonal AntibodyNIHNational Institute on Drug Abuse2023 to 2025$13,125,765May 1, 2023April 30, 2027KALNIK, MATTHEW Wreporter.nih.gov
Pitt-Ohio State Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,065,770February 1, 2007November 30, 2027RIDDLER, SHARONreporter.nih.gov
Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitroNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,884,300September 1, 2003April 30, 2029DAVIS, MARK MORRISreporter.nih.gov
HEALTH Center for Addictions Research and Cancer PreventionNIHNational Institute on Minority Health and Health Disparities2021 to 2024$12,882,144September 8, 2020April 30, 2026BEECH, BETTINA M.reporter.nih.gov
Vanderbilt HIV Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,733,650February 1, 2007November 30, 2027HAAS, DAVID Wreporter.nih.gov
Case Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,725,521December 1, 2024November 30, 2027YENDEWA, GEORGEreporter.nih.gov
Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,580,221June 1, 2025May 31, 2027SETTE, ALESSANDROreporter.nih.gov
CURE CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,461,433January 1, 2007November 30, 2027SPECTOR, STEPHEN Areporter.nih.gov
Columbia Collaborative HIV/AIDS Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,286,513February 1, 2007November 30, 2027SOBIESZCZYK, MAGDALENA ELZBIETAreporter.nih.gov
Cincinnati Children's Hospital Medical Center Vaccine and Treatment Evaluation Units (UM1 Clinical Trial Required)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,115,898December 11, 2019November 30, 2026FRENCK, ROBERT WILSONreporter.nih.gov
Center for Redox Biology and Cardiovascular DiseaseNIHNational Institute of General Medical Sciences2021 to 2025$12,065,347February 1, 2018June 30, 2028KEVIL, CHRISTOPHER Greporter.nih.gov
PDB MANAGEMENT BY THE RESEARCH COLLABORATORY FOR STRUCTURAL BIOINFORMATICSNIHNational Institute of General Medical Sciences2021 to 2023$12,006,722August 1, 2019September 18, 2024BURLEY, STEPHEN Kreporter.nih.gov
Human anti-viral immune responses in tissues and circulationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,930,741January 1, 2017February 28, 2027FARBER, DONNA L.reporter.nih.gov
Targeting the B Cell Response to Treat Antibody-Mediated RejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,789,092August 20, 2021May 31, 2028KNECHTLE, STUART JOHNSTONreporter.nih.gov
Durable Alteration of the Human Immune system after Infection or ImmunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,785,761June 8, 2009May 31, 2029CHUNG, RAYMOND Treporter.nih.gov
Task A71: Comprehensive In Vivo Screening of Viral Pathogens of Pandemic PotentialNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,745,278July 18, 2022July 17, 2025MORREY, JOHNreporter.nih.gov
Development of an Optimized Adjuvanted TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$11,645,061September 30, 2021September 30, 2025EVANS, JAYreporter.nih.gov
Preclinical and Translational Vaccine Development for HIV and Other Candidate Agents (PTVDS)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$11,597,222December 1, 2024November 30, 2025DENNY, TOMreporter.nih.gov
Reagent Resource Support Program for AIDS Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$11,522,629April 8, 2018April 7, 2025FREMONT, VALERIEreporter.nih.gov
KwaZulu-Natal Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,302,268December 1, 2024November 30, 2027ABDOOL KARIM, QUARRAISHAreporter.nih.gov
Advancing Transplantation Outcomes in ChildrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,293,854July 1, 2025June 30, 2028BRISCOE, DAVID M.reporter.nih.gov
Advanced Development of Vaccine Candidates for Antibiotic Resistant BacteriaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,268,155September 1, 2020March 31, 2027MALINOWSKI, FRANKreporter.nih.gov
The Johns Hopkins University-Blantyre Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,246,510February 15, 2007November 30, 2027TAHA, TAHA Ereporter.nih.gov
Administrative Supplement for the NCI P30 CCSG to extend partnerships with comprehensive cancer control coalitions to study implementation of evidence-based cancer control interventionsNIHNational Cancer Institute2021$11,079,774January 1, 1997March 31, 2022LYNCH, THOMAS JAMESreporter.nih.gov
Vaccines for fentanyl and its derivatives: A strategy to reduce illicit use and overdoseNIHNational Institute on Drug Abuse2022 to 2024$11,034,562February 1, 2019July 31, 2025PRAVETONI, MARCOreporter.nih.gov
Advancing Vaccine Adjuvant Research for Tuberculosis (TB)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$10,964,476September 30, 2022September 29, 2027BRITTON, WARWICKreporter.nih.gov
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,947,708February 5, 2007November 30, 2027GUPTA, AMITAreporter.nih.gov
Advanced Development of a Universal Influenza VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,853,574September 9, 2019April 24, 2025LOCHER, CHRISTOPHERreporter.nih.gov
Advanced Development of Vaccine Candidates for Biodefense and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,650,296September 9, 2019October 31, 2025CASPER, COREYreporter.nih.gov
Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.NIHNational Institute on Aging2022 to 2025$10,320,460February 15, 2022January 31, 2027AGADJANYAN, MICHAEL Greporter.nih.gov
Nonhuman Primate (NHP) Core Functional Genomics Laboratory for AIDS Vaccine Research and DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,303,422July 1, 2019June 30, 2020GALE, MICHAELreporter.nih.gov
ADJUVANT COMPARISON AND CHARACTERIZATIONNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$10,234,165September 1, 2022January 1, 2027FELGNER, PHILIPreporter.nih.gov
University of Rochester HIV/AIDS Clinical Trials Unit Administrative SupplementNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,156,163August 26, 2025November 30, 2027KEEFER, MICHAEL Creporter.nih.gov
Nonhuman Primate Core Humoral Immunology Laboratory for AIDS Vaccine Research and DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,129,006March 30, 2024March 29, 2025SHEN, SHAUNNAreporter.nih.gov
Thailand HIV/AIDS and Infectious Disease Clinical Trials Unit (THAI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,070,868March 15, 2007November 30, 2027SUPPARATPINYO, KHUANCHAIreporter.nih.gov
Advanced Development of a Multivalent Vaccine Candidate for Lassa FeverNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,931,387September 1, 2017January 31, 2027SCHNELL, MATTHIAS JOHANNESreporter.nih.gov
The Military HIV Research Program (MHRP) Clinical Trial UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,910,676December 10, 2013November 30, 2027ROBB, MERLIN Lreporter.nih.gov
The Johns Hopkins University - Uganda Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,910,249February 5, 2007November 30, 2027FOWLER, MARY GLENNreporter.nih.gov
Viral Immunity and VAccination (VIVA) Human Immunology Project Consortium (HIPC)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$9,862,919March 22, 2022February 28, 2027FERNANDEZ-SESMA, ANAreporter.nih.gov
Expanded SPF Rhesus Macaque Breeding Colony for AIDS ResearchNIHOffice of the Director, National Institutes of Health2021 to 2025$9,705,199August 1, 2016August 31, 2028BOHM, RUDOLF PAULreporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,640,870August 26, 2021September 30, 2024LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
DEVELOPMENT OF UM-1098: A NOVEL SYNTHETIC TH17 INDUCING ADJUVANT AND DELIVERY SYSTEMNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$9,566,206September 30, 2023September 29, 2026EVANS, JAYreporter.nih.gov
University of Washington Arboviral Research Network (UWARN)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,499,281May 22, 2020June 5, 2025VAN VOORHIS, WESLEY Creporter.nih.gov
Early in vivo Expressed Antigens and their Role in Virulence, Immune Response, and Vaccines for CoccidioidomycosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$9,218,182August 24, 2022July 31, 2027BARKER, BRIDGET MARIEreporter.nih.gov
A-Z Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,989,738February 1, 2007November 30, 2027GOEPFERT, PAUL A.reporter.nih.gov
Task V34: Master Cell Banks Manufacturing for Next Generation SARS-CoV-2 VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$8,647,922May 15, 2018May 14, 2028TRUSHEIM, HEIDIreporter.nih.gov
Simian Vaccine Evaluation Unit: Core Activities - Administrative and Technical SupportNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,478,988April 1, 2020March 31, 2027LEWIS, MARKreporter.nih.gov
San Francisco Bay Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,314,128March 2, 2007November 30, 2027BUCHBINDER, SUSANreporter.nih.gov
A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$8,293,749September 30, 2021August 31, 2026ZAIDI, MONEreporter.nih.gov
Consortia for Innovative AIDS Research in Nonhuman PrimatesNIHNational Institute of Allergy and Infectious Diseases2021$8,268,168May 1, 2016April 30, 2022BAROUCH, DAN H.reporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2022$8,267,350September 30, 2022September 29, 2025PRAVETONI, MARCOreporter.nih.gov
Manufacturing of Drug Product, Dual Aβ/tau Vaccine for Clinical TrialsNIHNational Institute on Aging2021 to 2023$8,244,109February 1, 2019January 31, 2025AGADJANYAN, MICHAEL Greporter.nih.gov
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,239,326January 15, 2008November 30, 2027GRINSZTEJN, BEATRIZreporter.nih.gov
A deep longitudinal analysis of next generation influenza vaccines in older adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$8,127,184January 1, 2022December 31, 2026UCAR, DUYGUreporter.nih.gov
cGMP Manufacture, Fill-Finish, Release, Analytical and Stability Testing and Stability Program of a Nanoparticle Based HIV Envelope VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$8,013,603August 30, 2022August 29, 2030HASSELL, THOMASreporter.nih.gov
External Quality Assurance Program Oversight Laboratory (EQAPOL)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$7,902,910September 30, 2024September 29, 2031DENNY, THOMASreporter.nih.gov
Advanced Development and Clinical Evaluation of an Entamoeba Histolytica VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$7,788,182September 21, 2018November 22, 2025FOX, CHRISTOPHERreporter.nih.gov
Integrating innate and adaptive pathways in vaccine responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$7,762,589April 1, 2014March 31, 2024RAVETCH, JEFFREY VICTORreporter.nih.gov
Seattle Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$7,698,581February 1, 2007November 30, 2027MCELRATH, MARGARET JULIANAreporter.nih.gov
University of Arizona Cancer Prevention Clinical Trials NetworkNIHNational Cancer Institute2021 to 2025$7,572,043August 16, 2019July 31, 2031THOMPSON, PATRICIA ANNreporter.nih.gov
Ad26 Based Therapeutic Vaccines for HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,518,476May 12, 2020April 30, 2027BAROUCH, DAN H.reporter.nih.gov
Advanced Development of Vaccines for FilovirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,417,867July 21, 2020December 31, 2026ELDRIDGE, JOHNreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers STATISTICAL, DATA MANAGEMENT AND COORDINATION CENTER (SDMCC)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,400,390September 30, 2025September 29, 2026BOUR, STEPHANreporter.nih.gov
Administrative Supplements for NIAID Regional Biocontainment Laboratories (RBL)NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$7,369,853September 23, 2021February 28, 2025ALEM, FARHANGreporter.nih.gov
DEVELOPMENT OF VACCINES FOR INFLUENZA USING AN IMMUNO-MODULATOR ADJUVANT AND MULTI-PLATFORM APPROACHNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$7,281,050September 30, 2023September 29, 2028EL-KAMMASH, BRUXANNEreporter.nih.gov
Adjuvant Development of the TLR4 Ligand BECC470s For Use in Influenza, S. aureus, and P. aeruginosa VaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$7,143,498September 30, 2023September 29, 2028SORENSON, GREGORYreporter.nih.gov
iCAN PREVENT: MD Anderson International Cancer Prevention Clinical Trials ConsortiumNIHNational Cancer Institute2021 to 2025$7,046,172August 15, 2019July 31, 2031VILAR SANCHEZ, EDUARDOreporter.nih.gov
TASK ORDER B-15: Model Development and Medical Countermeasure EvaluationNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$7,029,612October 24, 2022October 1, 2023GRIFFITHS, ANTHONYreporter.nih.gov
ADVANCED DEVELOPMENT OF LQ A LIPOSOME-BASED SAPONIN-CONTAINING ADJUVANT FOR USE IN PANSARBECOVIRUS VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,937,118September 30, 2023September 29, 2026COLLINS, NICOLASreporter.nih.gov
Molecular and Immunologic Analysis of the Pathobiology of Human AnthraxNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,892,629September 15, 2004August 31, 2025FARRIS, A DARISEreporter.nih.gov
Native-like Envelope Trimer Therapeutic Vaccination for Induction of Broadly Neutralizing Antibodies to Facilitate HIV Functional CureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,813,637April 14, 2020July 31, 2027RIDDLER, SHARONreporter.nih.gov
Development of a COVID-19 VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$6,733,518September 1, 2020October 31, 2023REED, STEVENreporter.nih.gov
Lyme Disease: B cell epitope discovery and mechanisms of antibody protectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,722,146September 16, 2019September 15, 2024MANTIS, NICHOLAS J.reporter.nih.gov
B and T Cell Biology of Protection from and Eradication of SIV/SHIV Infection - Administrative SupplementNIHNational Institute of Allergy and Infectious Diseases2021$6,714,942June 1, 2016May 31, 2022HUNTER, ERICreporter.nih.gov
Making antibody generation rapid, scalable, and democratic through machine learning and continuous evolutionNIHNational Cancer Institute2021 to 2024$6,686,758September 10, 2020August 31, 2025LIU, CHANG Creporter.nih.gov
Aurum Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,678,965December 1, 2020November 30, 2027CHURCHYARD, GAVIN JOHNreporter.nih.gov
A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum.NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,678,063May 1, 2019April 30, 2025RADOLF, JUSTIN Dreporter.nih.gov
Administrative Supplement for Upgrading the University of Pittsburgh Regional Biocontainment Laboratory within The Center for Vaccine ResearchNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$6,659,737August 22, 2022February 28, 2025DUPREX, WILLIAM PAULreporter.nih.gov
B Cell Epitope Discovery and Mechanisms of Antibody Protection: Responses to Dengue 4, Powassan, Chikungunya, and Venezuelan Equine Encephalitis VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,634,396September 16, 2023September 15, 2024FREMONT, DAVEDreporter.nih.gov
Advanced Development of Vaccine Candidates for Biodefense and Emerging Antibiotic-Resistant Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$6,612,767September 21, 2022January 18, 2026KRUISWIJK, CORINEreporter.nih.gov
Leveraging an ongoing longitudinal study of influenza vaccination to define immune signatures of response and risk of infection in older adults >75NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$6,605,926December 9, 2021November 30, 2026LENG, SEAN XIAOreporter.nih.gov
California-Mexico-Puerto Rico Partnership (CAMPO) Center for Prevention of HPV-related Cancer in HIV+ PopulationsNIHNational Cancer Institute2021 to 2025$6,605,241September 12, 2019July 31, 2026PALEFSKY, JOEL MICHAELreporter.nih.gov
Facility and Building System Upgrades Support for the Howard T. Ricketts Biocontainment LaboratoryNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$6,593,067September 16, 2021February 28, 2025ADAMS, ERIN JUNEreporter.nih.gov
Advanced Development of Vaccine Candidates for Biodefense and Emerging Antibiotic-Resistant Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$6,592,393September 23, 2022July 22, 2026NORTON, ELIZABETHreporter.nih.gov
Comparative Modeling to Inform Cervical Cancer Control PoliciesNIHNational Cancer Institute2021 to 2024$6,568,988September 8, 2020August 31, 2025KIM, JANE JOOYUNreporter.nih.gov
Task A68: Screening Vaccine (and Other Biologics) Platform Technologies using Coronavirus Mouse Immunogenicity as a Model SystemNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,550,363May 23, 2022September 30, 2026GRAHAM, RACHELreporter.nih.gov
Stellenbosch University Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,524,563April 15, 2007November 30, 2027HESSELING, ANNEKE CATHARINAreporter.nih.gov
Small-molecule activators of STING-signaling as novel adjuvants for flavivirus vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,461,817September 30, 2019September 29, 2024NELSON, JAYreporter.nih.gov
University of Washington (UW) Sexually Transmitted Infections (STI) Cooperative Research Center (CRC) - Syphilis Vaccine to Protect against Local and Disseminated T. pallidum InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$6,406,743August 1, 2019July 31, 2025WALD, ANNAreporter.nih.gov
Harnessing B cells for TB vaccine development to improve therapy of TB and TB-HIV coinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,398,428July 1, 2021June 30, 2027GENGENBACHER, MARTIN ALFONSreporter.nih.gov
DEVELOPMENT OF SMALL-MOLECULE DUAL ADJUVANT SYSTEM FOR INFLUENZA VIRUS VACCINENIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,359,752September 30, 2023September 29, 2028LAPEK, JENNIFERreporter.nih.gov
Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,330,175February 4, 2021January 31, 2026KAPPE, STEFAN HIreporter.nih.gov
DUAL AFFINITY RE-TARGETING (DART) MOLECULES FOR HIV-1 SUPPRESSIONNIHNational Institute of Allergy and Infectious Diseases2021$6,287,950September 15, 2015July 14, 2023NORDSTROM, JEFFREYreporter.nih.gov
BASE TITLE: PREVENT PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY AND INTERMEDIATE ENDPOINT BIOMAKERSTASK ORDER TITLE: VACCINES AGAINST FUSOBACTERIUM FOR FAP-AND LYNCH SYNDROME-ASSOCIANIHNational Cancer Institute2022 to 2024$6,227,249June 15, 2022May 15, 2025CLAPPER, MARGIE L.reporter.nih.gov
Southwest Clinical Trials Node: Clinical Research and Practice to Address Substance Use in Diverse, Rural, and Underserved PopulationsNIHNational Institute on Drug Abuse2021 to 2025$6,192,905June 1, 2019February 29, 2032PAGE, KIMBERLYreporter.nih.gov
A Clinical Trial of Three Broadly Neutralizing Antibodies and Analytic Treatment Interruption in Early-Treated Children in BotswanaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,096,179September 5, 2023June 30, 2028SHAPIRO, ROGER Lreporter.nih.gov
Design and testing of immunogens to elicit 10E8-like broadly neutralizing antibodies against HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,090,710July 8, 2019August 31, 2029SCHIFFNER, TORBENreporter.nih.gov
TO IDENTIFY NOVEL ADJUVANT CANDIDATES THAT CAN BE USED TO AUGMENT THE EFFICACY OF HUMAN VACCINES.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,022,974September 30, 2019April 30, 2026CARSON, DENNISreporter.nih.gov
Partnership for Prevention of HPV-Associated Cancers in People Living with HIV: Brazil, Mexico, and Puerto RicoNIHNational Cancer Institute2021 to 2025$5,948,066September 20, 2019July 31, 2026ELLSWORTH, GRANT B.reporter.nih.gov
B-CELL EPITOPE DISCOVERY AND MECHANISMS OF ANTIBODY PROTECTIONNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,936,710September 16, 2019August 31, 2025CROWE, JAMES Ereporter.nih.gov
Expanding the breadth, magnitude, and durability of PfSPZ vaccines by creating multi-strain vaccines, designer hybrid and genetically altered parasite vaccines and use of a unique adjuvant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,933,702April 8, 2021March 31, 2027SIM, B. KIM LEEreporter.nih.gov
DEVELOPMENT OF SAS A SYNTHETIC AS01-LIKE ADJUVANT SYSTEM FOR INFLUENZA VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,907,864September 30, 2023September 29, 2028BURKHART, DAVIDreporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,882,740August 26, 2021May 31, 2028LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
Discovery of adjuvants via novel modulation of innate immune pathways for vaccines against influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,841,904September 30, 2019April 30, 2026ESSER-KAHN, AARONreporter.nih.gov
Drivers of individual variation in influenza vaccine response and protection from infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,827,282July 14, 2022June 30, 2027COBEY, SARAHreporter.nih.gov
The Role of B cells in the Origin and Progression of Multiple SclerosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,776,308May 1, 2019April 30, 2027HAUSER, STEPHEN Lreporter.nih.gov
Cancer Immune Monitoring and Analysis CenterNIHNational Cancer Institute2023 to 2025$5,746,876September 30, 2017June 30, 2028WU, CATHERINE JU-YINGreporter.nih.gov
Rational design and efficacy testing of vaccines against HCVNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,737,237May 5, 2022April 30, 2027FUERST, THOMAS Rreporter.nih.gov
Computational models of naturally acquired immunity to falciparum malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,666,873April 1, 2020March 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
Small-molecule inducers of the cGAS/STING pathway as novel adjuvants for flu vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$5,636,289September 30, 2019September 29, 2024ADOLFO, GARCIA-SASTREreporter.nih.gov
Nonhuman Primate (NHP) Core Cellular Immunology Laboratory for AIDS Vaccine Research DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$5,634,048June 1, 2023May 31, 2024KAUR, AMITINDERreporter.nih.gov
Task V02: Manufacture of Influenza for Human Challenge Clinical TrialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,587,695May 15, 2018May 31, 2026HASSEL, THOMASreporter.nih.gov
Cervical, Anal & Oral HPV Persistence/Adolescent GirlsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,549,203May 15, 2007January 31, 2028DIAZ, ANGELAreporter.nih.gov
Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,526,401July 17, 2020June 5, 2025SAKUNTABHAI, ANAVAJreporter.nih.gov
Advanced Development of Vaccines for InfluenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,495,941September 9, 2019May 31, 2027STAERZ, UWEreporter.nih.gov
Small-molecule adjuvants testing pipeline (Influenza)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$5,486,225September 30, 2019September 29, 2024LEVY, OFERreporter.nih.gov
Molecular mechanisms of antibody-mediated immunotherapiesNIHNational Cancer Institute2021 to 2025$5,461,259April 1, 2016August 31, 2029RAVETCH, JEFFREY VICTORreporter.nih.gov
Cellular Immunology Core LaboratoryNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,413,068June 1, 2025May 31, 2026KAUR, AMITINDERreporter.nih.gov
Developing computational models to predict the immune response to B. pertussis booster vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,401,756March 10, 2020February 28, 2025PETERS, BJOERNreporter.nih.gov
Task V31: Process Development for a Panfungal VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,346,445January 20, 2023July 30, 2025FOUTS, TIMreporter.nih.gov
A clinical trial to evaluate the impact of broadly neutralizing antibody VRC01 on HIV viral reservoir and maintenance of suppression in a cohort of early-treated children in BotswanaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,339,746February 20, 2018January 31, 2026SHAPIRO, ROGER Lreporter.nih.gov
FDA approved IND 29644: Multicenter Phase 1 Trial to Evaluate Safety and Immunogenicity of Preventive Tau Vaccine, AV-1980R/A, in cognitively unimpaired preclinical AD participants.NIHNational Institute on Aging2025$5,308,961August 1, 2025July 31, 2030AGADJANYAN, MICHAEL Greporter.nih.gov
Optimization and testing of anti-methamphetamine antibody therapy to support pivotal clinical trials and commercializationNIHNational Institute on Drug Abuse2021 to 2022$5,281,643May 1, 2020February 29, 2024STEVENS, MISTY WARDreporter.nih.gov
Adjuvant Comparison and Characterization of Peanut AntigenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,238,569September 25, 2025September 24, 2026STAATS, HERMANreporter.nih.gov
Understanding and Mimicking TCR Recognition with Therapeutic Monoclonal Antibodies.NIHNational Cancer Institute2021 to 2025$5,214,422August 14, 2020July 31, 2027SCHEINBERG, DAVID Areporter.nih.gov
Advancement of a poxvirus antiviralNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,192,454March 12, 2020August 31, 2029CONNOR, JOHN Hreporter.nih.gov
HIV-1 Q23.17 Env: Engineering a novel immunogen to elicit broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,173,076June 23, 2021May 31, 2026SHAW, GEORGE Mreporter.nih.gov
Development of vaccination strategies to elicit broadly protective immunity against influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,165,779June 18, 2019June 30, 2029RAVETCH, JEFFREY VICTORreporter.nih.gov
High-throughput proteomics using submicroliter amounts of plasma for comprehensive assessment of the immune statusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,147,391April 9, 2020March 31, 2026STEEN, HANNOreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,116,475June 9, 2023March 31, 2028HALASA, NATASHA BASSAMreporter.nih.gov
Immune Cells and Secretory Pathways Leading to Human Systemic AutoimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,112,288May 1, 2019April 30, 2029PASCUAL, MARIA VIRGINIAreporter.nih.gov
Rapid structure-based software to enhance antibody affinity and developability for high-throughput screening: Aiming toward total in silico design of antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,047,322May 1, 2020April 30, 2027BLATTNER, FREDERICK Rreporter.nih.gov
Development of Therapeutic Candidates for Biodefense, Infections and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$5,018,496July 5, 2023May 31, 2028VOIGT, EMILYreporter.nih.gov
Task 12: Sexually Transmitted Infections Clinical Trials Group: Phase 2 Clinical Trial to Evaluate a Vaccine Candidate for Neisseria GonorrhoeaeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,969,800September 6, 2019June 30, 2026HOOK, EDWARDreporter.nih.gov
Evaluation of an OMV-adjuvanted Chimeritrope Vaccine against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,961,891September 30, 2018September 29, 2023MORICI, LISAreporter.nih.gov
The "Dynamics of the immune responses to repeat influenza vaccination exposures" (DRIVE) StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,955,723September 11, 2020June 30, 2026COBEY, SARAHreporter.nih.gov
Fine Mechanisms of Adaptive NK Cell Formation Against HIV and SIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,922,128August 20, 2021July 31, 2027REEVES, ROGER KEITHreporter.nih.gov
Mechanisms of human papillomavirus entryNIHNational Cancer Institute2021 to 2025$4,915,530August 17, 2020July 31, 2027DIMAIO, DANIEL C.reporter.nih.gov
Preclinical development of a vaccine for Nipah virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,912,518March 11, 2021February 28, 2027GEISBERT, THOMAS WILLIAMreporter.nih.gov
Antigen recognition and activation of HIV-specific B cell antigen receptorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,911,145March 20, 2019July 31, 2029ALAM, S. MUNIRreporter.nih.gov
Living in the post-Zika world: Impact of interactions between dengue and Zika viruses on diagnostics, antibody dynamics, and correlates of disease riskNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,905,886July 13, 2021April 30, 2027HARRIS, EVAreporter.nih.gov
Development of Vaccine Candidates for Biodefense and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2024$4,889,710June 7, 2024June 1, 2026BRUYETTE, DAVIDreporter.nih.gov
Large Scale T Cell Epitope Discovery:Global identification of epitopes derived from Zika (ZIKV), Chikungunya (CHIKV) viruses following natural infection and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,881,220September 30, 2019September 29, 2024MITCHELL, MAYAreporter.nih.gov
Structure based design of trimer interface epitope focused universal influenza vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,864,362March 12, 2020February 28, 2025CROWE, JAMES Ereporter.nih.gov
Strategically Engineered Multi-Antigen KSHV Vaccine: Integrating Humoral and Cellular Immunity for Effective ProtectionNIHNational Cancer Institute2025$4,857,475August 7, 2025July 31, 2029WU, TING-TINGreporter.nih.gov
Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,835,728December 1, 2020November 30, 2026ADAMS, JOHN Hreporter.nih.gov
HIV-1 Fusion Peptide-directed Vaccine Design Using Virus-like ParticlesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,825,382March 1, 2021February 28, 2027KONG, RUIreporter.nih.gov
Autonomously deploying, co-evolving SARS-CoV-2 antiviral: a new paradigm for pandemic preventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,817,583September 24, 2021August 31, 2024RODICK, ROBERTreporter.nih.gov
Novel Stem Cell Immunotherapy for MDR-TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,800,190June 4, 2021May 31, 2026JAGANNATH, CHINNASWAMYreporter.nih.gov
Human antibody-based countermeasures against the Wuhan Coronavirus SARS-CoV-2NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,799,861September 15, 2020August 31, 2025DIAMOND, MICHAEL Sreporter.nih.gov
Creating high-resolution, epitope-focused vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,794,402September 30, 2020July 31, 2025KIM, PETER Sreporter.nih.gov
Unmasking the roles of viral glycoproteins in oral transmission of KSHVNIHNational Cancer Institute2021 to 2025$4,786,354September 1, 2021August 31, 2026OGEMBO, JAVIER GORDONreporter.nih.gov
Identification of Metabolic and Immune Deficits in the Aged Population and Their Restoration to Achieve Youthful Anti-Influenza Vaccine ResponsivenessNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,757,817November 22, 2021October 31, 2026MARASCO, WAYNE A.reporter.nih.gov
Durable HIV Vaccine Targeting Mucosal EpitheliumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,751,308August 1, 2022July 31, 2027GAUDUIN, MARIE-CLAIRE ELISABETHreporter.nih.gov
Development of Non-Human Primate Models to Assess Immunological Mechanisms and Antigenic Targets of Protective Sporozoite (SPZ) Vaccines and Establish Superior Efficacy of Next Generation SPZ vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,717,265April 1, 2021March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Advanced Development of Vaccine Candidates for Biodefense and Emerging Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,706,565September 21, 2022April 30, 2027THAMMAVONGSA, VILASACKreporter.nih.gov
Immunologic control of HIV-1 through combination bNAbs and biologics.NIHNational Institute of Allergy and Infectious Diseases2022 to 2024$4,702,057July 5, 2019December 31, 2025CASKEY, MARINAreporter.nih.gov
DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,695,387September 30, 2023September 29, 2026NORTON, ELIZABETHreporter.nih.gov
Leveraging novel pediatric SHIVs to identify biomarkers of prophylactic efficacy of bnAb against breast milk HIV transmissionNIHNational Institute of Allergy and Infectious Diseases2025$4,686,370September 25, 2025August 31, 2029FOUDA AMOU OU, GENEVIEVE GINYreporter.nih.gov
A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidumNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,663,782April 22, 2024March 31, 2029MOODY, MICHAEL ANTHONYreporter.nih.gov
Heritable immunization of the white-footed mouse reservoir of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,657,626September 1, 2021August 31, 2026ESVELT, KEVINreporter.nih.gov
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding coloniesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,657,141May 1, 2021August 31, 2030BOSINGER, STEVEN EDWARDreporter.nih.gov
DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,647,135June 29, 2020May 31, 2026ANTIA, RUSTOM NOSHIRreporter.nih.gov
Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,634,490July 1, 2021December 31, 2026VOSS, JAMES EVENreporter.nih.gov
MYCOBACTERIUM TUBERCULOSIS (MTB) QUALITY ASSESSMENT PROGRAM (TBQA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,608,548January 1, 2023December 31, 2023COFFIN, JEANETTEreporter.nih.gov
Development of the INI-4001 and INI-2002 adjuvants within the context of a vaccine to prevent Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,583,801September 30, 2018September 29, 2024EVANS, JAYreporter.nih.gov
GVIRF2023NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,504,988August 23, 2018May 31, 2023FRIEDE, MARTINreporter.nih.gov
Cytotoxic T Cell Mediated Immunity to ChlamydiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,482,401July 1, 1996July 31, 2026STARNBACH, MICHAEL Nreporter.nih.gov
Maximizing germinal centers and somatic hypermutation to HIV Env immunogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,431,323February 1, 2016January 31, 2026CROTTY, SHANE Preporter.nih.gov
Vaccine and Treatment Evaluation Units: Wolbachia-Infected Aedes aegypti Mosquitos in Reducing Arboviral Infection BrazilNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,402,306February 4, 2020November 30, 2027ROUPHAEL, NADINEreporter.nih.gov
Molecular Analysis and Lineage Tracing of Influenza-Specific, Lung-Resident Memory B CellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,398,832April 7, 2020March 31, 2027RANDALL, TROY Dreporter.nih.gov
Dissecting Polyclonal Sera to Reveal Correlates of Productive Immune Responses to HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,391,888March 16, 2018February 29, 2028WARD, ANDREW BARRETTreporter.nih.gov
Breaking the Barrier to an HIV VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,382,000September 30, 2022July 31, 2027SAWYER, SARAreporter.nih.gov
An oral vaccine against Chlamydia trachomatisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,358,977April 19, 2024March 31, 2029ZHONG, GUANGMINGreporter.nih.gov
Optimizing glycan shield coverage, germline B cell receptor binding and epitope diversity of V2-apex targeted HIV-1 Env immunogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,308,687September 19, 2019August 31, 2029HAHN, BEATRICE Hreporter.nih.gov
VACCINES ADJUVANT DEVELOPMENT PROGRAM IN INFECTIOUS AND IMMUNE MEDIATED DISEASESNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,300,145September 30, 2023September 29, 2026DOWLING, DAVID JAMESreporter.nih.gov
PROJECT MANAGEMENT SUPPORT FOR COMMUNITY ENGAGEMENT ON TRANS-NIH THERAPEUTICS AND VACCINE TRIALSNIHNational Heart, Lung, and Blood Institute2021$4,297,649July 29, 2020January 28, 2021SHINGLEDECKER, DANIELreporter.nih.gov
KSHV Subunit Vaccine Candidates to Elicit Potent Humoral Immune Reponses against KSHV InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,284,115March 22, 2021February 28, 2027OGEMBO, JAVIER GORDONreporter.nih.gov
Combining germline-targeting, B cell immunofocusing and Env-Ab co-evolution strategies to induce HIV Envelope V2-apex broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,257,922April 1, 2021June 30, 2023ANDRABI, RAIEES AHMADreporter.nih.gov
Targeting HIV reservoirs in children with HIVIS DNA and MVA-CMDR vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,251,563February 1, 2018February 28, 2026ROBB, MERLIN Lreporter.nih.gov
Preventing TB with intravenous BCG in SIV-infected macaquesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,248,442May 5, 2021April 30, 2026SCANGA, CHARLES A.reporter.nih.gov
Influenza pathogenesis in pregnancyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,248,239June 14, 2021May 31, 2027ADAMS WALDORF, KRISTINA M.reporter.nih.gov
The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,208,331June 1, 2020July 31, 2030SESHADRI, CHETANreporter.nih.gov
Antibody-based therapy for fentanyl-related opioid use disorderNIHNational Institute on Drug Abuse2023$4,202,550September 30, 2023August 31, 2025DESAI, RAJEEV INDRAJITreporter.nih.gov
Imposing order on the family of ubiquitin-conjugating (E2) enzymes through intracellular perturbation with nanobodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,159,500September 30, 2019July 31, 2024PLOEGH, HIDDE L.reporter.nih.gov
Role of Inducible Bronchus Associated Lymphoid Tissue in Latent TuberculosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,152,012February 1, 2023January 31, 2027KHADER, SHABAANA A.reporter.nih.gov
Structure and Dynamics of the SARS-CoV-2 Spike ProteinNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,142,443July 12, 2021June 30, 2027MOTHES, WALTHER Hreporter.nih.gov
Inducing HIV-1 NAb Breadth by Native Trimer Prime-Boost VaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,133,062March 1, 2011May 31, 2025BINLEY, JAMES Mreporter.nih.gov
Development of mRNA-platform vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,121,318January 21, 2021December 31, 2026DAMRON, FREDRICK HEATHreporter.nih.gov
Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,114,200February 10, 2022January 31, 2027WILDER, BRANDON KEITHreporter.nih.gov
Development of an oral liver-targeted prime-and-trap malaria vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,104,491December 1, 2020November 30, 2026MURPHY, SEAN Creporter.nih.gov
Neutralizing the GBS hemolytic lipid toxinNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,096,432June 16, 2022May 31, 2027RAJAGOPAL, LAKSHMIreporter.nih.gov
A STINGing vaccine for TBNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,090,805June 1, 2020May 31, 2026BISHAI, WILLIAM RAMSESreporter.nih.gov
Cytomegalovirus (CMV), the gut barrier and immune dysfunction in HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,077,185March 15, 2021February 28, 2027SHACKLETT, BARBARA L.reporter.nih.gov
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of miceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,052,693April 14, 2021March 31, 2027FIKRIG, EROLreporter.nih.gov
A high-efficiency, low-cost, single-use purification technology for therapeutic antibody manufacturingNIHNational Institute of General Medical Sciences2021 to 2025$4,049,312September 1, 2019January 31, 2026HOWELL, DAVID W.reporter.nih.gov
Innovations in Functional B Cell Epitope Discovery for Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,031,164September 16, 2024September 15, 2026MANTIS, NICHOLASreporter.nih.gov
Defining functional humoral correlates of immunity to guide vaccine designNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,023,233November 24, 2020October 31, 2025BATISTA, FACUNDO DAMIANreporter.nih.gov
Modeling the ecology of tissue-resident T cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,020,006August 19, 2020May 31, 2026YATES, ANDREWreporter.nih.gov
Nucleoside-modified mRNA vaccine for prevention and treatment of genital herpesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,009,506April 15, 2019June 30, 2027FRIEDMAN, HARVEY MICHAELreporter.nih.gov
HIV-1 dynamics and evolution during trispecific broadly neutralizing antibody therapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,008,532April 8, 2021March 31, 2026TSIBRIS, ATHE M.reporter.nih.gov
Rational Systemic Characterization and Selection of Adjuvants for HIV Vaccine Candidates (R-CASA)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,983,710August 1, 2025July 31, 2026CHATTERJEE, ARNAB KUMARreporter.nih.gov
Selecting HA glycosylation for improved vaccine responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,957,417June 9, 2021May 31, 2027ZAIA, JOSEPHreporter.nih.gov
Novel therapeutic approaches to treatment of botulinum neurotoxin poisoningNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,954,829April 15, 2011June 30, 2027ICHTCHENKO, KONSTANTINreporter.nih.gov
World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,949,988February 1, 2016March 24, 2025WEAVER, SCOTT Creporter.nih.gov
ReMARk: A multi-level strategy to address disparities in rural HPV-related cancer preventionNIHNational Cancer Institute2022 to 2025$3,944,859September 22, 2022August 31, 2028STARAS, STEPHANIE A Sreporter.nih.gov
Efficacy of immunization with 4C-MenB in preventing experimental urethral infection with Neisseria gonorrhoeae.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,925,773July 1, 2021April 30, 2027DUNCAN, JOSEPH Areporter.nih.gov
A systems immunology approach for predicting poor responses to Hepatitis B vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,925,255September 17, 2021August 31, 2026HERATI, RAMINreporter.nih.gov
A systems immunology approach to evaluate malaria vaccine performance in endemic regions of KenyaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,921,000February 1, 2022January 31, 2027MOORMANN, ANN Mreporter.nih.gov
Tracking the evolutionary trajectory of neutralizing antibodies following BG505 SOSIP immunizationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,907,608June 16, 2023May 31, 2027DERDEYN, CYNTHIA ANNreporter.nih.gov
Development of multi-modal single-cell technology to dissect epitope specificity to HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,892,813June 26, 2015May 31, 2026BOSINGER, STEVEN EDWARDreporter.nih.gov
Novel Immunogens to Elicit Broadly Cross-reactive Antibodies That Target the Hemagglutinin Head Trimer InterfaceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,892,523August 20, 2021July 31, 2025AZOITEI, MIHAI LUCHIANreporter.nih.gov
Development of a recombinant protein vaccine for Chlamydia trachomatisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,885,058May 10, 2024March 31, 2029DARVILLE, TONIreporter.nih.gov
Discovery of Adjuvants for mRNA VaccinesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,882,045September 30, 2025September 29, 2026CARSON, DENNISreporter.nih.gov
Development of a novel TB vaccine safer and more effective than BCG based on a precisely controlled replication-limited Mycobacterium tuberculosis engineered for optimal in vivo growth and clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,876,556March 15, 2021February 28, 2027HORWITZ, MARCUS AARONreporter.nih.gov
Cellular and molecular programming of lung resident T cell memoryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,857,630May 1, 2020April 30, 2027KOHLMEIER, JACOB Ereporter.nih.gov
Developing broad-spectrum therapeutics against C. difficile toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,852,231February 11, 2021January 31, 2027JIN, RONGSHENGreporter.nih.gov
Mechanisms of protection against shigellosis in childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,843,317June 9, 2022May 31, 2027PASETTI, MARCELA Freporter.nih.gov
Identification of novel immunogenic proteins from Bordetella pertussisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,825,567June 9, 2021May 31, 2027DUBEY, PURNIMAreporter.nih.gov
Immune Dysfunction in HIV+ Opioid UsersNIHNational Institute on Drug Abuse2021 to 2025$3,823,539April 15, 2020January 31, 2027PAHWA, SAVITAreporter.nih.gov
Understanding Pandemic Evolution through Networked Data (UPEND)NIHNational Institute of Mental Health2023$3,822,251April 15, 2023April 14, 2026CROWELL, TREVOR ADAMreporter.nih.gov
Functional profiling of OSP-specific and other antibodies during shigella infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,818,268September 22, 2020August 31, 2030RYAN, EDWARD T.reporter.nih.gov
Statistical Issues in AIDS ResearchNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,816,097September 30, 1989March 31, 2029HUGHES, JAMES Preporter.nih.gov
Immune response to COVID-19 vaccine in HIV infected men and womenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,779,701September 23, 2021August 31, 2026RINALDO, CHARLES Rreporter.nih.gov
Role of ncRNA Surveillance Complex "RNA Exosome" in Class Switch Recombination and Somatic HypermutationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,761,466May 7, 2012April 30, 2027BASU, UTTIYAreporter.nih.gov
O-Specific Polysaccharide Responses and CholeraNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,758,033August 7, 2013March 31, 2030RYAN, EDWARD T.reporter.nih.gov
Development of a novel adjuvant strategy enabled by modulation of the physical properties of fungal mannansNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,755,681September 17, 2021August 31, 2026ZANONI, IVANreporter.nih.gov
Restoring age-dependent vaccine unresponsiveness by a novel ASP-1 adjuvant combinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,749,095August 1, 2021May 31, 2027LUSTIGMAN, SARAreporter.nih.gov
Immunity to CryptosporidiumNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,739,027January 1, 2020December 31, 2029HUNTER, CHRISTOPHER Areporter.nih.gov
Heterosubtypic immunity to influenza virus mediated by MHC-E-restricted memory NK cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,727,019September 24, 2021August 31, 2027JOST, STEPHANIEreporter.nih.gov
Discovery of Adjuvants that Direct T-cell Fates for Improved Safety and Efficacy in Vaccines Against Influenza and TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,714,524September 30, 2025September 29, 2026ESSER-KAHN, AARONreporter.nih.gov
A Phase II Evaluation of the Safety and Protective Efficacy of the Live Attenuated Tetravalent Dengue Vaccine TetraVax-DV with Challenge by the Recombinant DENV-2 Virus in a Dengue Endemic PopulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$3,713,909August 21, 2019July 31, 2025KIRKPATRICK, BETH DIANEreporter.nih.gov
"Corral and Kill" strategy for HIV eradication using MSC in an SIV modelNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,712,736March 23, 2020February 28, 2030DANDEKAR, SATYAreporter.nih.gov
Structure-based design of broad flavivirus immunogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,710,975September 24, 2021August 31, 2026LAI, JONATHAN R.reporter.nih.gov
Production of cGMP Native Flexibly Linked HIV-1 Envelope ProteinNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,709,483September 12, 2016March 31, 2028FOUTS, TIMOTHYreporter.nih.gov
Functional B-cell Epitope Discovery for Arthropod-Borne DiseasesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,708,329September 16, 2024September 15, 2027reporter.nih.gov
Flipped Germinal CentersNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,701,340September 17, 2021August 31, 2026WESEMANN, DUANE R.reporter.nih.gov
Exploiting antibody catalysis for treating CryptococcosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,699,200May 25, 2021April 30, 2027CASADEVALL, ARTUROreporter.nih.gov
Nonhuman Primate Core Virology Laboratory for AIDS Vaccine Research and DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,695,898December 22, 2017December 14, 2024DENNY, THOMASreporter.nih.gov
Combined cytokine therapy for sustained HIV remissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,695,050March 17, 2020February 28, 2026VELU, VIJAYAKUMARreporter.nih.gov
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissuesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,677,462March 10, 2022February 28, 2027ANDINO, RAULreporter.nih.gov
Evaluation of Antibody Responses Elicited by Zika Vaccination in Flavivirus-naïve and -experienced IndividualsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,665,742April 13, 2021March 31, 2027KREBS, SHELLY Jreporter.nih.gov
Studying factors controlling cancer progression and immune recognition in mouse modelsNIHNational Cancer Institute2022 to 2025$3,664,660September 20, 2022August 31, 2029JACKS, TYLER E.reporter.nih.gov
Structure, Function and Mechanistic Analysis of LAG3NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,664,179January 8, 2019December 31, 2028VIGNALI, DARIO AAreporter.nih.gov
Using immune complex vaccines to optimize antibody responses to HIV EnvNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,657,831March 12, 2020February 28, 2027HIOE, CATARINA Ereporter.nih.gov
Modeling and design of complex RNA structuresNIHNational Institute of General Medical Sciences2021 to 2025$3,656,040September 1, 2017July 31, 2027DAS, RHIJUreporter.nih.gov
Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$3,648,087September 25, 2021August 31, 2025GUSTAFSON, DAVID Hreporter.nih.gov
IND enabling CMC/safety/toxicology studies, submission of IND and pilot Phase 1 clinical trial with PV-1950R vaccine for Lewy Body Dementia (LBD)NIHNational Institute on Aging2024 to 2025$3,640,661June 5, 2024May 31, 2029AGADJANYAN, MICHAEL Greporter.nih.gov
Understanding Immune Evasion by HIV-1 RepliclonesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,617,103June 10, 2021May 31, 2027HALVAS, ELIAS K.reporter.nih.gov
Hyaluronidase mediated GBS DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$3,613,118July 14, 2025June 30, 2029RAJAGOPAL, LAKSHMIreporter.nih.gov
Optimizing AAV delivery of bNAbs for HIV preventionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,607,044November 24, 2021October 31, 2026GARDNER, MATTHEW RYANreporter.nih.gov
DEVELOPMENT OF A VACCINE CANDIDATE FOR DRUG-RESISTANT FUNGAL INFECTIONSNIHNational Institute of Allergy and Infectious Diseases2025$3,605,418September 30, 2025June 1, 2030NABORS, GARYreporter.nih.gov
Development of a Replicon RNA-based Vaccine against Dengue and ZikaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,590,945June 1, 2021May 31, 2026SHRESTA, SUJANreporter.nih.gov
Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-RenewalNIHNational Cancer Institute2021 to 2025$3,585,446July 1, 2010June 30, 2027NAKAGAWA, MAYUMIreporter.nih.gov
Mechanisms of B cell responses to particulate antigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,582,696July 1, 2021June 30, 2027CHENG, WEIreporter.nih.gov
Structure-Guided Design of Broadly Neutralizing Lassa Virus BiSpecific AntibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,575,135December 24, 2018November 30, 2024BRANCO, LUIS MANUELreporter.nih.gov
Phase 1a/1b Clinical Trials of Multivalent Opioid Vaccine ComponentsNIHNational Institute on Drug Abuse2023$3,569,552September 15, 2018March 31, 2028COMER, SANDRA Dreporter.nih.gov
PERSISTENCE OF IMMUNE RESPONSES TO THE RECOMBINANT ZOSTER VACCINE IN IMMUNE COMPROMISED HOSTS WITH END-STAGE RENAL DISEASE WITH AND WITHOUT KIDNEY TRANSPLANTATIONNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,559,912March 6, 2019February 28, 2029WEINBERG, ADRIANAreporter.nih.gov
Transforming HIV vaccine design with a hybrid technology that leverages features of mRNA and protein nanoparticle platformsNIHNational Institute of Allergy and Infectious Diseases2025$3,559,750September 26, 2025August 31, 2029HOFFMANN, MAGNUS ADRIAN GEROreporter.nih.gov
Assessing the effects of oral pre-exposure prophylaxis on pharmacokinetics of monoclonal and vaccine-induced antibodies among women vulnerable to HIV-1NIHNational Institute of Allergy and Infectious Diseases2025$3,554,273September 12, 2025August 31, 2029HUANG, YUNDAreporter.nih.gov
Chronic Wasting Disease VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,544,335July 8, 2021June 30, 2027MATHIASON, CANDACE K.reporter.nih.gov
The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccinationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,543,436March 1, 2022February 28, 2027TEIJARO, JOHN ROSSreporter.nih.gov
Adjuvant Development Program in the context of vaccines to protect against Y. pestis and Shigella.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,532,934September 30, 2018September 29, 2023ERNST, ROBERTreporter.nih.gov
Genetic, structural and functional profiling of the human antibody response to arenavirus infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,529,436August 22, 2022July 31, 2027BRINEY, BRYANreporter.nih.gov
Task A78: Mouse and Guinea Pig Models for Cytomegalovirus and Herpes Simplex VvirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,527,311November 4, 2022November 3, 2024MADDOX, GRANTreporter.nih.gov
Development of anti-LPS therapeutic antibodies for the treatment of Pseudomonas aeruginosa infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,521,872August 1, 2024July 31, 2029BARBIER, MARIETTEreporter.nih.gov
Combination nanovaccine-based immunization against influenza virus in the aged: immunity and protectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,518,508February 16, 2021January 31, 2027KOHUT, MARIAN Lreporter.nih.gov
Antibody dependent cellular cytotoxicity and HIV-1 mother to child transmissionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,515,485September 19, 2022July 31, 2027SAGAR, MANISHreporter.nih.gov
An ethnically diverse genomic reference resource for the human heavy and light chain immunoglobulin lociNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,511,108July 23, 2018August 31, 2027WATSON, COREY TAYLORreporter.nih.gov
Capsular serotype in group B Streptococcus colonization and diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,507,212June 8, 2021May 31, 2026RATNER, ADAM JONATHANreporter.nih.gov
Harnessing Highly Networked HLA-E-Restricted CTL Epitopes to Achieve a Broadly Effective HIV CureNIHNational Institute on Drug Abuse2023 to 2025$3,507,000April 1, 2023February 29, 2028GAIHA, GAURAV DASreporter.nih.gov
Inducing durable, protective immune memory against malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,488,192January 16, 2019December 31, 2023KAPPE, STEFAN HIreporter.nih.gov
Protective immunity elicited by distinct polysaccharide antigens of classical and hypervirulent KlebsiellaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,483,730September 1, 2023August 31, 2028ROSEN, DAVID A.reporter.nih.gov
Combination Adjuvants to Program Durable Immunity to Respiratory Viral and Fungal PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,479,164February 17, 2016April 30, 2027SURESH, MARULASIDDAPPAreporter.nih.gov
Evaluation of Memory Responses and Biomarkers from a Phase IEnterotoxigenic Escherichia coli (ETEC) Intramuscular SubunitVaccine with dmLT AdjuvantNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,467,638September 24, 2021August 31, 2026NORTON, ELIZABETH Breporter.nih.gov
A Vaccine for Lymphatic Filariasis, LFGuard™NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,448,456March 1, 2019November 30, 2027CARTER, DARRICK ALBERTreporter.nih.gov
Development of MecVax, a Cross Protective Subunit Vaccine for ETECNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,440,502June 1, 2023May 31, 2028ZHANG, WEIPINGreporter.nih.gov
Mechanistic Studies of Combination Adjuvants to Target B Cells in VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,438,006April 23, 2021March 31, 2027TEYTON, LUCreporter.nih.gov
Reducing Latent Viral Reservoirs in Infant MacaquesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,436,436August 1, 2014June 30, 2025HAIGWOOD, NANCY Lreporter.nih.gov
Unraveling yellow fever 17D vaccine attenuation: The role of type I interferon and innate immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,421,854February 15, 2016July 31, 2027RICE, CHARLES Mreporter.nih.gov
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, DOSE-RANGING STUDY TO COMPARE THE SAFETY AND EFFICACY OF 3 DOSE LEVELS OF AV-1 IN HEALTHY ADULTS CHALLENGED WITH A CONTROLLED HUMAN INFECTION SNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$3,418,636August 23, 2023July 22, 2025DURBIN, ANNA PALMERreporter.nih.gov
Sex and Age Differences in Immunity to Influenza (SADII)NIHNational Institute on Aging2021 to 2022$3,417,361September 30, 2018May 31, 2023KLEIN, SABRA L.reporter.nih.gov
Structural characterization of Fab-dimerized glycan-reactive antibodies that neutralize HIV-1NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,416,984September 17, 2021August 31, 2026ACHARYA, PRIYAMVADAreporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2025$3,410,308September 30, 2022July 31, 2028PRAVETONI, MARCOreporter.nih.gov
Novel bi-specific immunotherapeutic against high-threat Gram-negative pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,410,042February 21, 2019January 31, 2025PERLIN, DAVID Sreporter.nih.gov
Toward a universal influenza virus vaccine based on live attenuated NS1-deleted influenza virusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,407,387January 7, 2019December 31, 2023GARCIA-SASTRE, ADOLFOreporter.nih.gov
Immunobiology of Influenza Virus-related Critical Illness in Young HostsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,406,427September 18, 2020August 31, 2025RANDOLPH, ADRIENNE Greporter.nih.gov
Structure and function of the Plasmodium myosin XIV-actin glideosome.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,384,780May 11, 2017June 30, 2027TRYBUS, KATHLEEN Mreporter.nih.gov
Community-Centered Interventions for Improved Vaccine Uptake for COVID (CIVIC)NIHNational Institute on Minority Health and Health Disparities2021 to 2025$3,378,034April 26, 2021May 9, 2025MARSH, ERICA Ereporter.nih.gov
Comparison of High Dose vs. Standard Dose Influenza Vaccines in Lung Allograft RecipientsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,375,497February 18, 2022January 31, 2027HALASA, NATASHA BASSAMreporter.nih.gov
Structure, antigenicity, and function of HCMV fusogen gBNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,357,889June 8, 2021May 31, 2027HELDWEIN, EKATERINAreporter.nih.gov
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,343,705April 1, 2021March 31, 2026SCHRAMM, VERN L.reporter.nih.gov
Cross-Kingdom Vaccine Targeting Healthcare-Associated Priority PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,343,171January 9, 2019December 31, 2024IBRAHIM, ASHRAF S.reporter.nih.gov
Development of an mRNA-Based Therapeutic HIV/AIDS VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,336,113March 5, 2020February 28, 2026OKOYE, AFAMEFUNAreporter.nih.gov
Using parenteral combination adjuvants to induce pan-mucosal cellular and humoral immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,332,631June 21, 2022May 31, 2027MCLACHLAN, JAMES Breporter.nih.gov
Micro-Particle Delivery of a Potent Intracellular Adjuvant for a Universal Flu VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,332,208December 14, 2018November 30, 2024TING, JENNY Preporter.nih.gov
Cancer Immune-Interception for Lynch SyndromeNIHNational Cancer Institute2021 to 2025$3,326,163September 21, 2021August 31, 2026VILAR SANCHEZ, EDUARDOreporter.nih.gov
M. tuberculosis exosome detection for pediatric TB diagnosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,323,600June 1, 2025May 31, 2027LACOURSE, SYLVIAreporter.nih.gov
Innate Immunity Stimulation Effects on Biomarkers, Cognition, and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAANIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,321,272July 15, 2022June 30, 2027SCHOLTZOVA, HENRIETAreporter.nih.gov
ARIA Pathophysiology Characterized by in vivo Neuroimaging, Plasma Biomarkers and Post-Mortem ProteomicsNIHNational Institute of Neurological Disorders and Stroke2025$3,310,951June 4, 2025May 31, 2027WISNIEWSKI, THOMAS Mreporter.nih.gov
Vaccination with invariant MHC-II-linked accessory antigens for protection from HIV infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,308,638September 23, 2020August 31, 2025VEAZEY, RONALD S.reporter.nih.gov
The uptake and real-world effectiveness of emerging respiratory syncytial virus maternal vaccines and monoclonal antibodies on short- and long-term respiratory morbiditiesNIHNational Institute of Allergy and Infectious Diseases2025$3,304,164August 11, 2025July 31, 2029WU, PINGSHENGreporter.nih.gov
Trypanosome Transmission Biology in TsetseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,303,729December 17, 2021November 30, 2026AKSOY, SERAPreporter.nih.gov
Multimodal PET-CT imaging of SIVmac239 dynamics post-ART interruptionNIHNational Institute of Allergy and Infectious Diseases2025$3,302,677July 21, 2025June 30, 2029OKOYE, AFAMEFUNAreporter.nih.gov
Longitudinal study of health outcomes and mitigating factors in the aftermath of the COVID pandemicNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,300,853September 21, 2021July 31, 2027MOHANAN, MANOJreporter.nih.gov
SARS-CoV-2 vaccines based on RBDs with engineered glycosylation sitesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,300,000August 17, 2023July 31, 2026ALPERT, MICHAEL DAVIDreporter.nih.gov
Lipid-mediated fungal pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,299,415July 1, 2016August 31, 2027DEL POETA, MAURIZIOreporter.nih.gov
Development of 4-(aroylamino)piperidine-based entry inhibitors as anti-influenza therapeuticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,297,972April 2, 2021April 30, 2026RONG, LIJUNreporter.nih.gov
Development of a universal DISC vaccine strategy against congenital cytomegalovirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,297,927April 7, 2021March 31, 2027MCGREGOR, ALISTAIRreporter.nih.gov
Brief digital intervention to increase COVID-19 vaccination among individuals with anxiety or depressionNIHNational Institute of Mental Health2022$3,296,734September 1, 2022March 11, 2025NASH, DENISreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccines in Adult Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,293,620September 1, 2020June 30, 2025HALASA, NATASHA BASSAMreporter.nih.gov
Clearance and In Vivo Detection of Tau PathologyNIHNational Institute on Aging2021 to 2025$3,293,211August 1, 2008April 30, 2028SIGURDSSON, EINAR Mreporter.nih.gov
Examining IgG4 sialylation as a gain of function post-translation modification in IgG4-related diseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,291,872July 1, 2020June 30, 2025ANTHONY, ROBERT MCCULLOUGHreporter.nih.gov
B cell Epitope Discovery and Mechanisms of Antibody Protection for Enterovirus and Bunyavirus Entry ProteinsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,291,808September 16, 2024September 15, 2026reporter.nih.gov
Once Bitten: Acquisition of Malaria Adaptive Immunity (OBAMA - Immunity)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,285,014July 1, 2025June 30, 2028PRUDHOMMEOMEARA, WENDYreporter.nih.gov
Natural killer cell regulation of the germinal center HIV neutralizing antibody responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,284,070December 1, 2019November 30, 2025BRADLEY, TODD CHRISTOPHERreporter.nih.gov
Palliative Care Research Cooperative Group (PCRC): Refinement and ExpansionNIHNational Institute of Nursing Research2021 to 2022$3,268,072September 28, 2013June 30, 2023KUTNER, JEAN Sreporter.nih.gov
Advanced Development of a Combined Shigella-ETEC VaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,267,570June 9, 2023May 31, 2028BARRY, EILEEN M.reporter.nih.gov
Pathogenic low affinity CD8 T cells in malariaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,264,359September 17, 2021August 31, 2026LAMB, TRACEY JANEreporter.nih.gov
Designing HIV-1 envelope immunogens to maximize neutralization breadth through use of multiple founder envelope antigensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,259,509June 20, 2023May 31, 2027BOLTON, DIANE L.reporter.nih.gov
Programming Durable Immune Responses To VaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,255,877December 18, 2018December 31, 2028ELLEBEDY, ALI HASSANreporter.nih.gov
Phase I clinical trial of adoptive transfer of autologous folate receptor-alpha redirected CAR T cells for ovarian cancerNIHNational Cancer Institute2022 to 2025$3,252,105April 1, 2022August 31, 2027POWELL, DANIEL J.reporter.nih.gov
Engineering the Skin Immune System to Induce Systemic Immune ResponsesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,251,899March 4, 2021January 31, 2027FALO, LOUIS Dreporter.nih.gov
Glycoengineering eCD4-IgNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,249,324March 9, 2022February 28, 2025ALPERT, MICHAEL DAVIDreporter.nih.gov
Vaccine-mediated cross-alphavirus protection for a live attenuated FDA licensed chikungunya virus vaccineNIHNational Institute of Allergy and Infectious Diseases2025$3,248,576July 25, 2025June 30, 2029COFFEY, LARK Lreporter.nih.gov
Human Monoclonal Antibodies for Encephalitic AlphavirusesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,248,015July 20, 2022June 30, 2027CROWE, JAMES Ereporter.nih.gov
Escape of maternal plasma broadly neutralizing antibody as a mechanism of mother to child HIV transmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,247,236September 1, 2021August 31, 2025PERMAR, SALLIE R.reporter.nih.gov
Combining germline-targeting, B cell immunofocusing and Env-Ab coevolution strategies to induce HIV Envelope V2-apex broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,245,040April 1, 2021May 31, 2027ANDRABI, RAIEES AHMADreporter.nih.gov
Evolution of T cell immunity in blood and tissues over childhoodNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,243,813March 16, 2022February 28, 2027FARBER, DONNA L.reporter.nih.gov
A novel Lyme disease vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,240,479June 7, 2022May 31, 2027FIKRIG, EROLreporter.nih.gov
Novel nanoparticulate adjuvants to enhance HIV-1 Env specific mucosal antibody responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,234,356July 3, 2019June 30, 2025KASTURI, SUDHIR PAIreporter.nih.gov
Genetic and Structural Basis for Virus Neutralization of ParamyxovirusesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,230,785September 16, 2024September 15, 2027reporter.nih.gov
An experimentally-refined, dynamic gene regulatory network model of T-cell memoryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,230,746March 8, 2021February 28, 2027BARSKI, ARTEMreporter.nih.gov
Novel Methods to Inform HIV/TB Clinical Trial DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,228,180September 1, 2011August 31, 2025REDDY, KRISHNA Preporter.nih.gov
A versatile structure-based therapeutic platform for development of VHH-based antitoxin and antiviral agentsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,217,894August 4, 2023July 31, 2027SHOEMAKER, CHARLES BIXreporter.nih.gov
Reverse Vaccinology in SHIV Infected Macaques as a Molecular Guide for HIV-1 Vaccine DesignNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,216,371March 11, 2021February 28, 2026SHAW, GEORGE Mreporter.nih.gov
Viper Resource Grant at Texas A&M University-KingsvilleNIHOffice of the Director, National Institutes of Health2021 to 2025$3,214,960April 15, 2003April 30, 2029SANCHEZ, ELDA E.reporter.nih.gov
Drivers of strain-specific and strain-transcendent antimalarial immunity in childhoodNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,209,021June 17, 2020May 31, 2026GREENHOUSE, BRYAN Rreporter.nih.gov
B cell clonal selection in gut-associated germinal centersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,203,164September 17, 2020August 31, 2025VICTORA, GABRIEL Dreporter.nih.gov
Identification of Novel Syk/Raf-1 Mediated CLR Ligands as Vaccine AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,198,798September 30, 2025September 29, 2026EVANS, JAYreporter.nih.gov
Development of a Chimeric Syphilis Vaccine Candidate to Combat Local, Disseminated and Congenital Syphilis InfectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,194,893April 15, 2024March 31, 2029CAMERON, CAROLINE Ereporter.nih.gov
Synthesis and Evaluation of Carbohydrate Vaccine AdjuvantsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,192,190June 10, 2022May 31, 2027NGUYEN, HIEN Mreporter.nih.gov
Host Responses to the Pore-Forming Toxin Listeriolysin ONIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,191,205April 1, 2021March 31, 2027SEVEAU, STEPHANIE M Mreporter.nih.gov
To Develop and Manufacture an Inactivated SARS-CoV-2 Vaccine Using Blood Pathogen Reduction TechnologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,181,780September 1, 2020April 30, 2026GOODRICH, RAYMONDreporter.nih.gov
Defining the role of T cell help in germinal centers by intercellular enzymatic labelingNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,176,273September 21, 2022July 31, 2027VICTORA, GABRIEL Dreporter.nih.gov
Development of human adaptive immunity to Staphylococcus aureusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,170,541March 5, 2021February 28, 2027BUBECK WARDENBURG, JULIANEreporter.nih.gov
Rational development of a vaccine against tick-borne rickettsiosesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,166,318August 1, 2022July 31, 2027FANG, RONG MEGANreporter.nih.gov
Mechanistic and functional dissection of inflammaging in Down syndromeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,165,277September 1, 2022August 31, 2027KHOR, BERNARDreporter.nih.gov
Transmission dynamics and fitness of reemerging St. Louis encephalitis virus in mosquito vectors and West Nile virus naïve and immune avian reservoirsNIHNational Institute of Allergy and Infectious Diseases2025$3,161,373July 22, 2025June 30, 2029COFFEY, LARK Lreporter.nih.gov
Early life B cell responses and inflammation following SARS-CoV-2 infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,160,521September 17, 2021August 31, 2026FOUDA AMOU OU, GENEVIEVE GINYreporter.nih.gov
Epitope-focused vaccine strategies against Zika virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$3,153,813August 1, 2018July 31, 2023NUSSENZWEIG, MICHEL Creporter.nih.gov
System Biological Analyses of Innate and Adaptive Responses to VaccinationNIHNational Institute of Allergy and Infectious Diseases2021$3,147,703March 1, 2021June 30, 2023PULENDRAN, BALIreporter.nih.gov
Development of a Multi-species Vaccine for Prevention of Bacterial Otitis MediaNIHNational Institute on Deafness and Other Communication Disorders2022 to 2024$3,145,522January 1, 2022December 31, 2025MCOSKER, CHARLES C.reporter.nih.gov
Analysis of a novel Crimean-Congo hemorrhagic fever vaccine and its mechanism of protection in rodent modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,145,040August 25, 2022July 31, 2026SCHNELL, MATTHIAS JOHANNESreporter.nih.gov
CD4+ T cells and neoantigens in melanoma immunotherapy.NIHNational Cancer Institute2021 to 2025$3,143,740December 1, 2020November 30, 2026WANG, RONGFUreporter.nih.gov
Coordinated studies in monkeys and humans to assess the immunological impact of rectal Chlamydia trachomatis infection on protection against genital infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,139,154April 1, 2023March 31, 2028VOJTECH, LUCIA Nreporter.nih.gov
Maternal Antibody-Mediated Enhancement of Dengue PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,138,902March 5, 2021February 28, 2026SHRESTA, SUJANreporter.nih.gov
Mechanisms of Protection and Durability for a Live Attenuated Tetravalent Dengue VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,135,970February 1, 2019January 31, 2029DIEHL, SEAN A.reporter.nih.gov
Shigella Conjugate Vaccine (SCV4) Development, Characterization, and Pre-clinical EvaluationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,134,727June 23, 2023May 31, 2028RYAN, EDWARD T.reporter.nih.gov
B-Cell Epitope Discovery and Mechanisms of Antibody Protection for ZIKV, MARV, VEEV Envelope ProteinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,133,973September 16, 2019September 15, 2024DORANZ, BENJAMINreporter.nih.gov
CONTROL AND ACTIVATION OF THE TUMOR NECROSIS FACTOR RECEPTORSNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,130,533February 1, 2020June 30, 2025WAGNER, GERHARDreporter.nih.gov
Cervicovaginal microbiome, mucosal immunity, and pathogen factors that contribute to spontaneous clearance of Chlamydia trachomatisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,127,515June 1, 2022May 31, 2027BROTMAN, REBECCA M.reporter.nih.gov
Intestinal microbiota-mediated rotavirus vaccine failureNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,123,686September 19, 2022July 31, 2027GEWIRTZ, ANDREW Treporter.nih.gov
Mechanisms of Enhanced Neutralizing Antibody Responses to Rhinovirus CNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,122,828March 20, 2020February 28, 2026BOCHKOV, YURY Areporter.nih.gov
Structure and immunogenicity of novel trimeric HIV-1 Env immunogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,119,393September 19, 2019August 31, 2025KONG, XIANGPENGreporter.nih.gov
Targeted immune therapies in heart transplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,118,293February 1, 2023January 31, 2026ABDI, REZAreporter.nih.gov
Structural interrogation of vaccine- and infection-induced B cell responsesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,116,277February 22, 2022January 31, 2027BAJIC, GORANreporter.nih.gov
Molecular and structural characterization of broadly neutralizing anti-HCV antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,115,747February 15, 2023January 31, 2028BAILEY, JUSTIN RICHARDreporter.nih.gov
Preclinical studies of a Cryptococcus vaccine for AIDS patientsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,109,260February 11, 2016January 31, 2027LODGE, JENNIFER K.reporter.nih.gov
Universal room temperature stable influenza nanovaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,103,165January 24, 2019December 31, 2024NARASIMHAN, BALAJIreporter.nih.gov
Uncovering latent factors underlying weak and robust responses to influenza vaccine in healthy and obese older adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,095,170July 13, 2022June 30, 2027ALCORN, JOHN Freporter.nih.gov
Conjugate vaccines for prevention and treatment of cryptococcosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,088,569March 2, 2020February 28, 2026CASADEVALL, ARTUROreporter.nih.gov
The impact of T cell selection on vaccine durabilityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,085,906September 24, 2021August 31, 2027SU, LAURAreporter.nih.gov
Molecular Mechanisms of Adjuvant Triplet CombinationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,084,459March 12, 2021February 28, 2026CHEVRIER, NICOLASreporter.nih.gov
EXTENSION OF ESCUDDO FOLLOW-UP FROM FIVE YEARS TO 7.5 YEARS (REFERRED TO AS ESCUDDO-7)NIHNational Cancer Institute2025$3,083,060March 26, 2025September 15, 2025reporter.nih.gov
Immunological characterization of rationally-designed vaccines against plague in mice and non-human primate modelsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,082,735February 1, 2021July 31, 2026CHOPRA, ASHOK Kreporter.nih.gov
TCR-dependent and epigenetic mechanisms guiding influenza-specific CD4+ T cell responses in the lungNIHNational Institute of Allergy and Infectious Diseases2025$3,078,308August 1, 2025July 31, 2029HALE, JEFFREY SCOTTreporter.nih.gov
Project 2VIDA! SARS-CoV-2 Vaccine Intervention Delivery for Adults in Southern CaliforniaNIHNational Institute on Minority Health and Health Disparities2021 to 2025$3,077,210April 23, 2021January 31, 2027SKAATHUN, BRITTreporter.nih.gov
Mechanisms of combined CD40/TLR adjuvant-elicited cellular immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,071,761March 25, 2021February 28, 2026KEDL, ROSS Mreporter.nih.gov
Rapid response for pandemics: single cell sequencing and deep learning to predict antibody sequences against an emerging antigenNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,071,572September 16, 2021August 31, 2025RAY, ANIMESHreporter.nih.gov
Novel delivery platform and antigen design for an effective COVID-19 vaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,066,236August 11, 2020July 31, 2027MITTAL, SURESH Kreporter.nih.gov
Translational studies of hookworm infection in GhanaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,065,354February 22, 2022January 31, 2027CAPPELLO, MICHAELreporter.nih.gov
Mechanisms of Innate Immune Evasion by Mycobacterium TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,061,547January 1, 2017December 31, 2026PHILIPS, JENNIFER Areporter.nih.gov
Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD preventionNIHNational Institute on Aging2021 to 2025$3,052,023September 30, 2021June 30, 2027OUKRAINTSEVA, SVETLANA V.reporter.nih.gov
Building the foundations of commensal vaccinesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,047,222September 23, 2022August 31, 2027FISCHBACH, MICHAEL ANDREWreporter.nih.gov
HIV-1 vaccine-elicited antibodies target envelope glycansNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,044,804June 15, 2015July 31, 2025SAUNDERS, KEVIN Oreporter.nih.gov
Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cellsNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$3,043,595August 18, 2022July 31, 2025KEOGH, MICHAEL-CHRISTOPHERreporter.nih.gov
Systems biological assessment of vaccination-induced protective immunity in African childrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,984February 1, 2022January 31, 2027PULENDRAN, BALIreporter.nih.gov
Enhancing cytotoxic lymphocytes in a TB vaccine strategyNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,037,076February 25, 2022January 31, 2027FLYNN, JOANNE L.reporter.nih.gov
GMP MANUFACTURE OF CLINICAL GRADE THERAPEUTIC VACCINE FOR THE TREATMENT OF PATIENTS WITH CHRONIC HBVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,034,670June 5, 2018March 31, 2025NAKAAR, VALERIANreporter.nih.gov
Using Disadvantage Indices in Pandemic Vaccine Allocation and Beyond to Promote Health OpportunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,031,954July 1, 2022June 30, 2027SCHMIDT, THOMAS HARALDreporter.nih.gov
Structure-guided engineering to increase respiratory syncytial virus G protein immunogenicityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,030,788May 19, 2022April 30, 2027DUBOIS, REBECCA MICHELLEreporter.nih.gov
Therapeutic vaccination to augment stringent response-specific T-cell immunity to MTB persistersNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,027,518March 17, 2020February 28, 2025KARAKOUSIS, PETROS Creporter.nih.gov
Effect of natural and engineered variations on structure and biophysics of SARS-CoV-2 spikeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,026,517February 1, 2022January 31, 2027ACHARYA, PRIYAMVADAreporter.nih.gov
MAb Passive Vaccination against Acinetobacter baumanniiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,021,383September 25, 2017August 31, 2027SPELLBERG, BRAD Jreporter.nih.gov
Understanding the mechanisms of antibody-mediated transcytosis of ZIKV within the placentaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,021,123June 11, 2020May 31, 2026SUTHAR, MEHUL SHAMALreporter.nih.gov
Clonal Dynamics of the antibody responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,017,736January 1, 2017December 31, 2026VICTORA, GABRIEL Dreporter.nih.gov
Design of single-shot sequential immunization regimens for HIV using atomic layer deposition technology.NIHNational Institute of Allergy and Infectious Diseases2025$3,017,032August 8, 2025July 31, 2029IRVINE, DARRELL Jreporter.nih.gov
The role of Trained Immunity and Mitochondrial dysfunction on INnate immunity in children and adolescents aGing with PHIV (TIMING-PHIV)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,016,481March 21, 2022February 28, 2027FUNDERBURG, NICHOLAS T.reporter.nih.gov
Respiratory Virus Vaccine and Adjuvant ExplorationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000April 19, 2019March 31, 2025BARIC, RALPH Sreporter.nih.gov
A Unique Automated Bioreactor for Rearing Aseptic Mosquitoes from Larvae to Adults to Support Manufacture of Sanaria PfSPZ ProductsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000July 18, 2018March 31, 2025BILLINGSLEY, PETER F.reporter.nih.gov
Development of a ZIKA viral pseudoinfectious virus as ZIKA vaccine candidate (STTR Phase II)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000August 1, 2017March 31, 2026PANG, XIAOWUreporter.nih.gov
DEVELOPMENT OF COVALENTLY BOUND HYALURONIC ACID AS AN ADJUVANT FOR MULTIVALENT LYME DISEASE VACCINENIHNational Institute of Allergy and Infectious Diseases2024$2,999,999September 30, 2024September 29, 2027PETILLO, PETER Areporter.nih.gov
eCD4-Ig for preventing and treating obstetric HIV infectionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,999,760August 13, 2020May 31, 2026MARTINS, MAURICIO DE AGUIARreporter.nih.gov
VESIVAX TLR7 FORMULANIHNational Institute of Allergy and Infectious Diseases2024$2,999,352September 1, 2024August 31, 2027HO, SAMONreporter.nih.gov
Universal Influenza A/B VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,998,889August 7, 2020April 30, 2026BAGLEY, KENNETH Creporter.nih.gov
Vaccine Induced Immune-Inflammatory Response and Cardiovascular RiskNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,998,175April 1, 2021March 31, 2026CHENG, SUSANreporter.nih.gov
A genetically modified Plasmodium falciparum sporozoite vaccine attenuated at the late-liver stageNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,998,001April 21, 2020March 31, 2027SIM, B. KIM LEEreporter.nih.gov
Recombinant West Nile Virus Vaccine Adjuvanted with SLA-LSQ Optimize Formulation of VSA AdjuvantNIHNational Institute of Allergy and Infectious Diseases2022$2,997,218July 5, 2022July 5, 2025CLEMENTS, DAVIDreporter.nih.gov
Increasing Availability of Emulsion Adjuvants via Synthetic BiologyNIHNational Institute of Allergy and Infectious Diseases2022$2,996,311August 30, 2022August 29, 2025KEMPINSKI, CHASEreporter.nih.gov
Personal tumor neoantigens for immunity against chronic lymphocytic leukemiaNIHNational Cancer Institute2022 to 2025$2,996,021June 1, 2011January 31, 2027WU, CATHERINE JU-YINGreporter.nih.gov
Integrin activator-adjuvanted DNA vaccine against Trypanosoma cruzi infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,995,034July 14, 2022June 30, 2026MARATHI, UPENDRAreporter.nih.gov
Progressing PfSPZ vaccines for malaria to licensure and commercializationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,994,338April 14, 2023March 31, 2027HOFFMAN, STEPHEN LEVreporter.nih.gov
Live-attenuated Rift Valley fever vaccines: comparative mechanisms of trans-placental transmission and vaccine efficacy for developing fetusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,993,583March 1, 2020February 28, 2027HARTMAN, AMY Lreporter.nih.gov
Novel vaccine strategies to induce V2 apex-directed broad neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,993,032July 4, 2019June 30, 2025VERKOCZY, LAURENT KARLreporter.nih.gov
Development of a Group B Streptococcus bioconjugate vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,991,364March 12, 2019May 31, 2027HARDING, CHRISTIANreporter.nih.gov
Research and Development to Establish a Small Animal Model as a Significant Resource of High-Value Single-Domain AntibodiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,990,687March 1, 2018August 31, 2025KIRILOV, MILENreporter.nih.gov
Intranasal Vaccine Against Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,988,409July 12, 2022June 30, 2026GOMES-SOLECKI, MARIAreporter.nih.gov
Development of World's First Fully Human Broad Spectrum Anti-Snake VenomNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,987,953August 14, 2019July 31, 2026GLANVILLE, JACOBreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
PPD Development LPWilmington, NC3$685.1 million0$0
Fred Hutchinson Cancer CenterSeattle, WA52$652.8 million0$0
Duke UniversityDurham, NC79$459.8 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY45$349.9 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA35$290.8 million0$0
Emory UniversityAtlanta, GA95$274.4 million0$0
Johns Hopkins UniversityBaltimore, MD80$249.1 million0$0
Scripps Research Institute, theLa Jolla, CA50$233.1 million0$0
Family Health InternationalDurham, NC2$214.7 million0$0
ST. Jude Children's Research HospitalMemphis, TN12$165.1 million0$0
University of PennsylvaniaPhiladelphia, PA56$143.3 million0$0
Seattle Children's HospitalSeattle, WA30$141.9 million0$0
University of Maryland BaltimoreBaltimore, MD60$135.8 million0$0
University of WashingtonSeattle, WA64$134.3 million0$0
Massachusetts General HospitalBoston, MA58$117.8 million0$0
Vanderbilt University Medical CenterNashville, TN37$117.1 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC60$101.3 million0$0
Washington UniversitySaint Louis, MO79$100.7 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA59$100.2 million0$0
University of Georgia Research Foundation IncAthens, GA28$97 million0$0
University of California, San FranciscoSan Francisco, CA55$95.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY37$93.9 million0$0
Stanford UniversityStanford, CA50$81 million0$0
University of ChicagoChicago, IL35$76.5 million0$0
Yale UniversityNew Haven, CT55$75.6 million0$0
Boston Children's HospitalBoston, MA26$71.1 million0$0
University of Alabama at BirminghamBirmingham, AL48$70.5 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA21$69.1 million0$0
Oregon Health & Science UniversityPortland, OR37$68.6 million0$0
University of California, San DiegoLa Jolla, CA41$68 million0$0
University of California Los AngelesLos Angeles, CA36$67.1 million0$0
Tulane University of LouisianaNew Orleans, LA22$64 million0$0
Columbia University Health SciencesNew York, NY32$62.5 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA13$60.9 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH19$60 million0$0
New York University School of MedicineNew York, NY28$58.5 million0$0
Rockefeller UniversityNew York, NY23$57 million0$0
University of California at DavisDavis, CA34$55.1 million0$0
University of Michigan at Ann ArborAnn Arbor, MI47$54.2 million0$0
Technical Resources International, Inc.Bethesda, MD2$52.4 million0$0
Brigham and Women's HospitalBoston, MA22$52 million0$0
Beth Israel Deaconess Medical CenterBoston, MA14$48.5 million0$0
Fisher Bioservices, Inc.Rockville, MD2$47.9 million0$0
Advanced Bioscience Laboratories, Inc.Kensington, MD7$47.2 million0$0
Westat, Inc.Bethesda, MD1$45.2 million0$0
University of California-IrvineIrvine, CA24$44.2 million0$0
University of Texas Med BR GalvestonGalveston, TX30$41.7 million0$0
University of MinnesotaMinneapolis, MN39$41.5 million0$0
University of Colorado DenverAurora, CO37$40.7 million0$0
Sanaria, Inc.Rockville, MD19$39.2 million0$0
University of UtahSalt Lake City, UT22$37.1 million0$0
University of Wisconsin-MadisonMadison, WI29$37 million0$0
University of MontanaMissoula, MT9$35.6 million0$0
Ohio State UniversityColumbus, OH35$35.1 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA28$34.3 million0$0
University of RochesterRochester, NY17$34.1 million0$0
Albert Einstein College of MedicineBronx, NY30$33.4 million0$0
Fundacion InciensaSan Jose2$32.6 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD14$32.6 million0$0
Dana-Farber Cancer InstBoston, MA20$30.4 million0$0
University of FloridaGainesville, FL25$30.2 million0$0
Battelle Memorial InstituteColumbus, OH3$30.1 million0$0
Saint Louis UniversitySaint Louis, MO10$29.7 million0$0
University of TX MD Anderson Can CTRHouston, TX17$29.1 million0$0
Midwest Research InstituteKansas City, MO3$29 million0$0
Institute for Molecular MedicineHuntington Beach, CA4$27.5 million0$0
Massachusetts Institute of TechnologyCambridge, MA22$26.3 million0$0
Wistar InstitutePhiladelphia, PA10$26.1 million0$0
University of California-BerkeleyBerkeley, CA12$26.1 million0$0
Baylor College of MedicineHouston, TX8$25.6 million0$0
Access to Advanced Health InstituteSeattle, WA4$25.1 million0$0
Thomas Jefferson UniversityPhiladelphia, PA14$24.9 million0$0
Boston University Medical CampusBoston, MA15$24.1 million0$0
Case Western Reserve UniversityCleveland, OH11$23.9 million0$0
Kaiser Foundation Research InstituteOakland, CA8$23 million0$0
University of IowaIowa City, IA25$22.9 million0$0
Digital Infuzion, Inc.Rockville, MD2$22.8 million0$0
Harvard Medical SchoolBoston, MA20$21.4 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL16$21.1 million0$0
University of Miami School of MedicineCoral Gables, FL12$21 million0$0
New Mexico State UniversityLas Cruces, NM1$20.7 million0$0
Banner HealthPhoenix, AZ1$20.4 million0$0
University of Maryland, College ParkCollege Park, MD14$20 million0$0
University of Missouri-ColumbiaColumbia, MO16$19.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX24$19.5 million0$0
University of VirginiaCharlottesville, VA21$19.2 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM15$19.1 million0$0
International Aids Vaccine InitiativeNew York, NY6$18.3 million0$0
Georgia State UniversityAtlanta, GA14$18.1 million0$0
SUNY at BuffaloAmherst, NY15$18.1 million0$0
HDT Bio CorporationSeattle, WA10$18 million0$0
Mayo Clinic RochesterRochester, MN19$17.8 million0$0
University of Cape TownRondebosch4$17.4 million0$0
University of Texas HLTH Science CenterSan Antonio, TX13$17 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ12$16.2 million0$0
Texas Biomedical Research InstituteSan Antonio, TX11$16 million0$0
University of Southern CaliforniaLos Angeles, CA11$15.6 million0$0
Hackensack University Medical CenterHackensack, NJ5$15.6 million0$0
Colorado State UniversityFort Collins, CO14$15.5 million0$0
Asociacion Civil Impacta Salud Y EducacnLima1$15.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,664$1,618,107,0290$0
20241,754$1,652,532,4620$0
20231,812$1,761,134,1340$0
20221,824$2,049,185,5700$0
20211,818$2,352,108,3130$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 24 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 8 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)PA-24-187NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 2,402 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 2,402 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 2,402 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 2,402 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 2,402 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 2,402 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 2,402 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.