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Data / Research funding / Hepatitis

Hepatitis: 962 NIH awards ($1.9B) to 265 organizations

962 NIH awards ($1.9B) in the NIH spending category Hepatitis, to 265 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 962 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$472,070,715December 1, 2024November 30, 2025CURRIER, JUDITH S.reporter.nih.gov
AIDS Clinical Trial Group Laboratory CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$56,714,107January 1, 2014November 30, 2027ALDROVANDI, GRACE Mreporter.nih.gov
University of North Carolina Global HIV Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,477,809February 1, 2007November 30, 2027ERON, JOSEPH Jreporter.nih.gov
UCLA AIDS Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,546,764February 1, 2007November 30, 2027LANDOVITZ, RAPHAEL Jreporter.nih.gov
Boston HIV CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,445,869January 15, 2007November 30, 2027KURITZKES, DANIEL R.reporter.nih.gov
Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer RiskNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$18,807,472August 1, 2018August 31, 2030DURAND, CHRISTINE MARIEreporter.nih.gov
NIAID VIROLOGY QUALITY ASSURANCE (VQA)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,732,468June 21, 2025June 20, 2026DENNY, THOMASreporter.nih.gov
International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,840,939May 1, 2025April 30, 2027ROHNER, ELIANEreporter.nih.gov
Center for Cellular Metabolism Research in OklahomaNIHNational Institute of General Medical Sciences2021 to 2025$15,159,612February 5, 2021January 31, 2027XIA, LIJUNreporter.nih.gov
Pitt-Ohio State Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,065,770February 1, 2007November 30, 2027RIDDLER, SHARONreporter.nih.gov
Hepatobiology and Toxicology COBRENIHNational Institute of General Medical Sciences2021 to 2025$12,863,981June 10, 2016March 31, 2027MCCLAIN, CRAIG J.reporter.nih.gov
Vanderbilt HIV Clinical Trials Unit (CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,733,650February 1, 2007November 30, 2027HAAS, DAVID Wreporter.nih.gov
CURE CTUNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,461,433January 1, 2007November 30, 2027SPECTOR, STEPHEN Areporter.nih.gov
AIDS Linked to the IntraVenous Experience (ALIVE) StudyNIHNational Institute on Drug Abuse2021 to 2025$12,226,379January 1, 2014May 31, 2030MEHTA, SHRUTI Hreporter.nih.gov
Durable Alteration of the Human Immune system after Infection or ImmunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,785,761June 8, 2009May 31, 2029CHUNG, RAYMOND Treporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Indiana University Data Coordinating CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$11,773,646August 1, 2018June 30, 2029TU, WANZHUreporter.nih.gov
Mays Cancer Center at UT Health SANIHNational Cancer Institute2021 to 2025$11,193,809August 1, 1997July 31, 2026ZHENG, LEIreporter.nih.gov
Reagent Program for HIV and other Infectious DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$10,735,388October 15, 2023January 13, 2024RASHID, SUJATHAreporter.nih.gov
Addressing risk through Community Treatment for Infectious disease and Opioid use disorder Now (ACTION) among justice-involved populationsNIHNational Institute on Drug Abuse2021 to 2025$10,550,278September 30, 2020July 31, 2026SPRINGER, SANDRA ANNreporter.nih.gov
Thailand HIV/AIDS and Infectious Disease Clinical Trials Unit (THAI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,070,868March 15, 2007November 30, 2027SUPPARATPINYO, KHUANCHAIreporter.nih.gov
Southern Liver Health CohortNIHNational Cancer Institute2023 to 2025$10,038,112September 21, 2021August 31, 2027HOYO, CATHRINEreporter.nih.gov
The Johns Hopkins University - Uganda Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$9,910,249February 5, 2007November 30, 2027FOWLER, MARY GLENNreporter.nih.gov
Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Supporting Financial Sustainability, Advanced Methods, and Knowledge TranslationNIHNational Institute on Drug Abuse2021 to 2025$8,690,640July 15, 2015April 30, 2030SCHACKMAN, BRUCE Rreporter.nih.gov
Data Coordinating Center for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) ContinuationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$8,663,508May 1, 2002June 30, 2028SHADE, DAVID Mreporter.nih.gov
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,239,326January 15, 2008November 30, 2027GRINSZTEJN, BEATRIZreporter.nih.gov
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients (THINKER-NEXT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,767,541April 15, 2021March 31, 2027SCHAUBEL, DOUGLAS EARLreporter.nih.gov
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug TourismNIHNational Institute on Drug Abuse2021 to 2024$6,868,774April 1, 2020January 31, 2026STRATHDEE, STEFFANIE A.reporter.nih.gov
Ancillary Studies of NAFLD and NASH in HIV infected AdultsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,132,391March 21, 2020January 31, 2026CHALASANI, NAGA Preporter.nih.gov
Johns Hopkins HIV Clinical CohortNIHNational Institute on Drug Abuse2021 to 2024$5,955,256July 1, 2014March 31, 2026MOORE, RICHARD DOUGLASreporter.nih.gov
Rational design and efficacy testing of vaccines against HCVNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,737,237May 5, 2022April 30, 2027FUERST, THOMAS Rreporter.nih.gov
Improvements to the Regional Biocontainment Research Facilities at the University of MissouriNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$5,667,997September 23, 2021February 28, 2025LORSON, CHRISTIAN L.reporter.nih.gov
Chicago Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,330,849February 1, 2007November 30, 2027ACHENBACH, CHAD Jreporter.nih.gov
A Randomized Controlled Trial of Prophylaxis with Direct-acting Antivirals for Kidney Transplantation from Hepatitis C virus-infected donor to Uninfected Recipients (PREVENT-HCV)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,162,956March 25, 2022February 28, 2027DURAND, CHRISTINE MARIEreporter.nih.gov
High-throughput proteomics using submicroliter amounts of plasma for comprehensive assessment of the immune statusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,147,391April 9, 2020March 31, 2026STEEN, HANNOreporter.nih.gov
Integrating Addiction and Infectious Diseases Services into Primary Care in Rural SettingsNIHNational Institute on Drug Abuse2021 to 2025$4,664,222August 1, 2021May 31, 2027ALTICE, FREDERICK LEWISreporter.nih.gov
Non-alcoholic Fatty Liver Disease and Cardiovascular Disease in Hispanics/LatinosNIHNational Heart, Lung, and Blood Institute2021 to 2022$4,589,716September 1, 2019August 31, 2024KIZER, JORGE Rreporter.nih.gov
Increasing Access to Hepatitis C Treatment in Opioid Endemic Rural Areas: the Kentucky Viral Hepatitis Treatment (KeY Treat) StudyNIHNational Institute on Drug Abuse2021 to 2023$4,371,481September 30, 2018July 31, 2025HAVENS, JENNIFER Rreporter.nih.gov
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,204,220May 15, 2015June 30, 2030FLEXNER, CHARLES W.reporter.nih.gov
Integrating HCV services into HIV programs for PWID in IndiaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,184,487July 8, 2019June 30, 2025MEHTA, SHRUTI Hreporter.nih.gov
RADx Innovation Funnel for Hepatitis B Diagnostics - Coordination CenterNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,074,004September 30, 2024September 29, 2026SCHACHTER, STEVEN C.reporter.nih.gov
A novel diagnostic Kit for Hepatocellular CarcinomaNIHNational Cancer Institute2021 to 2023$3,993,675September 1, 2012August 31, 2025LU, XUANYONGreporter.nih.gov
A systems immunology approach for predicting poor responses to Hepatitis B vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,925,255September 17, 2021August 31, 2026HERATI, RAMINreporter.nih.gov
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseNIHNational Institute on Drug Abuse2021 to 2025$3,865,844September 25, 2022January 31, 2029OWENS, DOUGLAS Kreporter.nih.gov
A Rhesus Macaque Model of HIV and HBV co-infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,842,980March 20, 2021February 28, 2026BURWITZ, BENJAMIN Jreporter.nih.gov
Spatio-temporal Methods for Surveillance of the Opioid SyndemicNIHNational Institute on Drug Abuse2021 to 2025$3,748,657September 1, 2025August 31, 2029KLINE, DAVID Mreporter.nih.gov
Pathogenesis of youth onset pre-diabetes and Type 2 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,716,431September 22, 2016July 31, 2026CAPRIO, SONIAreporter.nih.gov
Conduct Synthesis and Acquire Batches of Compounds for Subsequent Biological In Vitro and In Vivo TestingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,702,250April 1, 2024March 31, 2025MIDDLETON, MARKreporter.nih.gov
Novel Determinants for Progression of Non-Alcoholic Fatty Liver Disease to Hepatocellular Carcinoma and Other Health OutcomesNIHNational Cancer Institute2021 to 2025$3,678,371September 7, 2021August 31, 2026YUAN, JIAN-MINreporter.nih.gov
Estrogen Administration for the Treatment of NASH in Postmenopausal WomenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,638,994August 1, 2021May 31, 2027MILLER, KAREN Kreporter.nih.gov
Clinical & Immunological Study of Treatment Withdrawal in E-Ag Negative Hepatitis BNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,618,437September 1, 2016June 30, 2026COOPER, STEWARTreporter.nih.gov
NIH: Spatial Models of Intrahepatic Hepatitis Virus Propagation in HumansNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,593,236February 7, 2022January 31, 2027RIBEIRO, RUY Mreporter.nih.gov
Assessing the effects of oral pre-exposure prophylaxis on pharmacokinetics of monoclonal and vaccine-induced antibodies among women vulnerable to HIV-1NIHNational Institute of Allergy and Infectious Diseases2025$3,554,273September 12, 2025August 31, 2029HUANG, YUNDAreporter.nih.gov
Interactions between neutrophils and cholangiocytes in alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,548,231September 25, 2021June 30, 2027NATHANSON, MICHAEL Hreporter.nih.gov
Acute/chronic limitations to transcriptional RNAi therapies for infectious and other liver diseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,515,317August 1, 2006July 31, 2026KAY, MARK Areporter.nih.gov
Structural and Mechanistic basis for RNA SilencingNIHNational Institute of General Medical Sciences2021 to 2025$3,507,599August 1, 2018July 31, 2028MACRAE, IAN JOHNreporter.nih.gov
Clinical Research on Nonalcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,430,513September 15, 2002June 30, 2027LOOMBA, ROHITreporter.nih.gov
Human Genetic determinants of HBV recoveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,412,348September 30, 1999December 31, 2026THOMAS, DAVID Lreporter.nih.gov
Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST)NIHNational Institute of Allergy and Infectious Diseases2025$3,411,692September 24, 2025August 31, 2030NAGGIE, SUSANNAreporter.nih.gov
Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veteransNIHNational Institute on Drug Abuse2021 to 2025$3,379,762September 30, 2021July 31, 2027BENNETT, ALEXANDER Sreporter.nih.gov
Promoting remote and secondary risk prevention services in rural settingsNIHNational Institute on Drug Abuse2022 to 2025$3,349,340September 30, 2022July 31, 2027PHO, MAI TUYETreporter.nih.gov
Immunologic correlates of functional cure of HBV with immune checkpoint blockadeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,338,136May 22, 2020April 30, 2026LAUER, GEORG MICHAELreporter.nih.gov
A geospatial analysis of hotspots and targeted injection settings pilot intervention for HIV prevention among people who inject drugs in Baltimore, MarylandNIHNational Institute on Drug Abuse2021 to 2025$3,292,995July 1, 2020May 31, 2027LATKIN, CARL Areporter.nih.gov
A smartphone-enabled point-of-care HCV Ag diagnostic using catalytic nanoparticles and AI-enhanced image processingNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$3,284,055September 9, 2022June 30, 2027SHAFIEE, HADIreporter.nih.gov
IL-27R signaling as a negative regulator of innate and adaptive anti-cancer immunity in hepatocellular carcinomaNIHNational Cancer Institute2022 to 2025$3,273,154August 1, 2022July 31, 2027KOLTSOVA, EKATERINAreporter.nih.gov
Longitudinal Study of Early NAFLD Progression and the Gut Microbiome in Asian Americans, Native Hawaiians and WhitesNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,263,901September 26, 2022June 30, 2027LIM, UNHEEreporter.nih.gov
Lead optimization of Hepatitis B Virus ribonuclease H inhibitorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,253,243December 1, 2020November 30, 2026TAVIS, JOHN Ereporter.nih.gov
Implementation of telemedicine and social network driven HIV service uptake for comprehensive HIV service integration in rural syringe service programsNIHNational Institute on Drug Abuse2023 to 2025$3,234,132August 1, 2023May 31, 2028FALADE-NWULIA, OLUWASEUNreporter.nih.gov
Examine Individual and Clinical Factors Affecting Liver Disease ManagementNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,219,854September 15, 2022May 31, 2027MA, GRACE X.reporter.nih.gov
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular CarcinomaNIHNational Cancer Institute2021 to 2025$3,197,232January 18, 2021December 31, 2026ZHU, YAZHENreporter.nih.gov
Neutralizing antibody responses during natural control of acute hepatitis B with and without HIV-1 coinfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,186,484August 1, 2022July 31, 2027BAILEY, JUSTIN RICHARDreporter.nih.gov
Collaborative Integration of HCV Molecular Virology and Mathematical ModelingNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,185,361August 1, 2010May 31, 2027UPRICHARD, SUSAN L.reporter.nih.gov
Intestinal proteases in alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2025$3,182,397September 20, 2025August 31, 2029SCHNABL, BERND G.reporter.nih.gov
Novel macrophage mediated signals regulate the immunoregulatory environment of the neonatal liverNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,176,680September 15, 2025September 14, 2029NIJAGAL, AMARreporter.nih.gov
CTRP and Metabolic ControlNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,168,077July 15, 2010June 30, 2028WONG, GUANG WILLIAMreporter.nih.gov
Launching HBV with RNA to assess antiviral resistance and explore fundamental aspects of virus-host biologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,156,556February 10, 2020April 30, 2030RICE, CHARLES Mreporter.nih.gov
Extracellular vesicle cargo and risk of NAFLD and NASH in U.S. youthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,153,279April 15, 2022February 28, 2027DISTEFANO, JOHANNA Kreporter.nih.gov
Impact of harm reduction care in HIV clinical settings on stigma and health outcomes for PLWH who use drugsNIHNational Institute on Drug Abuse2021 to 2025$3,152,106September 30, 2021June 30, 2027HAWK, MARY ELIZABETHreporter.nih.gov
Molecular and structural characterization of broadly neutralizing anti-HCV antibodiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,115,747February 15, 2023January 31, 2028BAILEY, JUSTIN RICHARDreporter.nih.gov
Epigenetics of human Hepatic Stellate Cells (HSCs) in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,103,795May 15, 2014August 31, 2027KISSELEVA, TATIANAreporter.nih.gov
The Impact of HCV Treatment in HIV/HCV coinfected and HCV monoinfected Incarcerated Persons on HCV EliminationNIHNational Institute on Drug Abuse2021 to 2024$3,045,888September 30, 2020August 31, 2025IRVIN, RISHAreporter.nih.gov
GMP MANUFACTURE OF CLINICAL GRADE THERAPEUTIC VACCINE FOR THE TREATMENT OF PATIENTS WITH CHRONIC HBVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$3,034,670June 5, 2018March 31, 2025NAKAAR, VALERIANreporter.nih.gov
A Randomized Trial to Test the Efficacy of a Partner Navigation Intervention for HCV Treatment among Young Adult People who Inject DrugsNIHNational Institute on Drug Abuse2022 to 2025$3,017,588June 1, 2022March 31, 2027MORRIS, MEGHAN Dreporter.nih.gov
Analysis of Chemical Structures and Therapeutic Activity of Agents for HIV, TB, and HBV (CHEMDB)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,016,918September 30, 2024September 29, 2025SUMNER, LOUISEreporter.nih.gov
Multi-level Evaluation of Racial/ethnic Disparities in Liver Disease OutcomesNIHNational Cancer Institute2021 to 2025$3,010,755March 18, 2021February 28, 2027KANWAL, FASIHAreporter.nih.gov
Mechanisms of T Cell Quiescence and ExhaustionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,001,713March 1, 2019February 28, 2029SARKAR, SUROJITreporter.nih.gov
Preclinical development of capsid assembly modulators for the treatment of chronic hepatitis B virus infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,000,000May 24, 2021April 30, 2025COBURN, GLEN ANDREWreporter.nih.gov
Targeting hepatitis B virus cccDNA during HBV/HIV co-infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,993,820August 20, 2024July 31, 2029PLOSS, ALEXANDERreporter.nih.gov
Molecular Magnetic Resonance of Hepatic FibrogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,974,604July 3, 2019March 31, 2028CARAVAN, PETER Dreporter.nih.gov
Anchimerically Activatable Anti-Zika/Dengue ProTidesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,946,770August 1, 2021July 31, 2026WAGNER, CARSTON R.reporter.nih.gov
Novel IL-23 inhibitor for the treatment of alcohol associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,935,798September 20, 2020August 31, 2025LOOMBA, ROHITreporter.nih.gov
Moderately CHO-restricted diet as treatment targeting improvement in hepatic lipid and insulin sensitivity in adolescents with NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,928,802May 5, 2021July 31, 2026GOSS, AMY MISKIMONreporter.nih.gov
Dynamic Strategies for the clinical management of HIV diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,926,858August 9, 2012May 31, 2028HERNAN, MIGUELreporter.nih.gov
Kinetic and structural basis for SARS-CoV-2 RNA-dependent RNA polymerase specificity and inhibitionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,889,190July 16, 2021June 30, 2027JOHNSON, KENNETH ALLENreporter.nih.gov
Non-invasive etiology-adjusted precision liver cancer risk predictionNIHNational Cancer Institute2025$2,876,456August 5, 2025July 31, 2029HOSHIDA, YUJINreporter.nih.gov
Cardiovascular Risk Reduction in an Aging HIV-Infected Population: The Impact of HCV Co-InfectionNIHNational Institute on Aging2021 to 2023$2,851,326May 1, 2019January 31, 2025TRIANT, VIRGINIA ATHENAreporter.nih.gov
Clinical Resource for Alcoholic Hepatitis InestigationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,850,908August 1, 2016April 30, 2027SUN, ZHAOLIreporter.nih.gov
Computational modeling for HCV vaccine trial design and optimal vaccine-based combination interventionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,842,189November 1, 2021October 31, 2026DAHARI, HARELreporter.nih.gov
Cooperative mechanisms of HIV-enhanced liver fibrogenesis in HBV CoinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,836,440July 15, 2020June 30, 2027CHUNG, RAYMOND Treporter.nih.gov
Significance and mechanisms of hepatic ChREBPα induction via post-translational modifications in diet-induced NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,830,469April 1, 2014May 31, 2027YIN, LEIreporter.nih.gov
Data-Driven Mathematical and Computational Modeling of Hepatitis D Infection and Treatment ResponseNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,802,377February 15, 2020January 31, 2026DAHARI, HARELreporter.nih.gov
Selective mTORC1 inhibition to prevent and treat NAFLD and NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,795,850July 15, 2016May 31, 2026ARANY, ZOLTAN Preporter.nih.gov
Novel Biomarkers for Post-Liver Transplant NASH FibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,777,764July 18, 2022May 31, 2027ARTEEL, GAVIN Ereporter.nih.gov
Targeting hepatic mitochondrial function in humans with NAFLD using insulin sensitizersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,715,093April 15, 2022March 31, 2027NORTON, LUKEreporter.nih.gov
Jagged-Notch signaling in NASH/fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,685,447February 15, 2019June 30, 2028PAJVANI, UTPALreporter.nih.gov
Spinal cord injury causes liver pathology and metabolic dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,668,295April 1, 2021March 31, 2027MCTIGUE, DANA Mreporter.nih.gov
Mechanisms of Advanced NAFLD Disparities in Hispanics: A Multi-level AnalysisNIHNational Institute on Minority Health and Health Disparities2021 to 2025$2,655,656January 1, 2021November 30, 2026SETIAWAN, VERONICA WENDYreporter.nih.gov
Hereditary Genetics of Hepatocellular CarcinomaNIHNational Cancer Institute2022 to 2025$2,655,540February 1, 2022June 30, 2027WANGENSTEEN, KIRK Jreporter.nih.gov
Discovery of novel therapeutic targets for NASH through deep phenotyping of human knockouts and mechanistic studiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,636,860September 15, 2022June 30, 2026TABAS, IRA Areporter.nih.gov
Cutaneous biomarkers of pediatric non-alcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,615,502June 17, 2022March 31, 2027MOUZAKI, MARIALENAreporter.nih.gov
Regulation of Metabolism by FGF21NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,614,390July 15, 2015June 30, 2028POTTHOFF, MATTHEW JOSEPHreporter.nih.gov
Systems Genetics Dissection of Non-alcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,612,818July 1, 2019March 31, 2028LUSIS, ALDONS JAKEreporter.nih.gov
Recruitment for the efficacy trial of Tele-Harm Reduction in a federally qualified health center operated syringe services programNIHNational Institute on Drug Abuse2021 to 2024$2,609,496May 1, 2021April 30, 2026TOOKES, HANSEL EMORYreporter.nih.gov
Bio-Psycho-Social Drivers of Disparities in Liver Disease Progression among Korean Americans with Hepatitis B InfectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,557,384April 12, 2021March 31, 2026JUON, HEE-SOONreporter.nih.gov
First-in-human study of a potent anti-HBsAg neutralizing antibodyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,534,231March 20, 2023February 28, 2027CASKEY, MARINAreporter.nih.gov
Tumor-promoting and tumor-suppressive roles of Hepatic Stellate Cell Subpopulations in NASH-HCCNIHNational Cancer Institute2021 to 2025$2,533,680July 20, 2021June 30, 2026SCHWABE, ROBERT F.reporter.nih.gov
Leveraging HCV Phylogenetic Networks to Prevent HIV and Other Blood Borne Infections Among People Who Inject DrugsNIHNational Institute on Drug Abuse2021$2,520,000June 1, 2021May 31, 2026AKIYAMA, MATTHEWreporter.nih.gov
ANALYSIS OF INTRAHEPATIC MACROPHAGE PROFILES FOR PREDICTING RISK OF FIBROSIS DEVELOPMENT IN PATIENTS WITH DIFFERENT TYPES OF CHRONIC LIVER DISEASENIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,517,485April 1, 2021March 31, 2027STEVENSON, HEATHER Lreporter.nih.gov
Role of antibodies in hepatitis E virus infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,508,951April 19, 2023March 31, 2028FENG, ZONGDIreporter.nih.gov
Understanding human antibody responses to chronic viral hepatitis CNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,488,538January 17, 2022December 31, 2026LAW, MANSUNreporter.nih.gov
Immune correlates of protection against hepacivirus persistence.NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,486,556April 1, 2021September 30, 2025KAPOOR, AMITreporter.nih.gov
TERT mRNA lipid nanoparticles to extend telomeres to treat alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$2,484,849September 10, 2020August 31, 2025RAMUNAS, JOHNreporter.nih.gov
The role of AEG-1 in NASH and NASH-HCCNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,484,379July 25, 2016December 31, 2025SARKAR, DEVANANDreporter.nih.gov
HBV Capsid EffectorsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,475,992June 1, 2017February 28, 2027SCHINAZI, RAYMOND FELIXreporter.nih.gov
Molecular Magnetic Resonance Imaging of InflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,451,935August 1, 2019November 30, 2029GALE, ERIC MICHAELreporter.nih.gov
Dissecting the Role of Arachidonic Acid Metabolic Pathways Involved in Resolution Versus Progression of PM-Induced Cardiometabolic ToxicityNIHNational Institute of Environmental Health Sciences2022 to 2025$2,445,294February 11, 2022November 30, 2026ARAUJO, JESUS ANTONIOreporter.nih.gov
New generation of long acting nucleos(t)ides and immune stimulant for treatment of chronic hepatitis BNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,444,033March 10, 2022February 28, 2027OSNA, NATALIA ALEKSANDRreporter.nih.gov
Digital, Community-Led, Social Action Initiative to Reduce Opioid Vulnerability and HIV/HCV in Rural Areas of the Midwest and AppalachiaNIHNational Institute on Drug Abuse2021 to 2023$2,437,500May 1, 2019April 30, 2025ALBARRACIN, DOLORESreporter.nih.gov
A binational cohort of the intersection between substance use, HIV, and associated comorbidities among people who inject drugs in San Diego, CANIHNational Institute on Drug Abuse2025$2,437,310July 15, 2025May 31, 2030STRATHDEE, STEFFANIE A.reporter.nih.gov
Integrative Physiology of Thyroid Hormone Receptors and Nuclear Receptor CorepressorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,435,612June 1, 1991April 30, 2029LAZAR, MITCHELL A.reporter.nih.gov
Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland siteNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,432,868June 15, 2002June 30, 2027DASARATHY, SRINIVASANreporter.nih.gov
YAP signaling in the pathogenesis of NAFLD in people living with HIVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,422,019September 26, 2023July 31, 2028CHUNG, RAYMOND Treporter.nih.gov
ATP Binding Cassette Transporters in Health and DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,408,231April 9, 2021January 31, 2025TARLING, ELIZABETH JOANNAreporter.nih.gov
Defining the role of the RNA modification N6-methyladenosine during Flaviviridae virus infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,403,276June 1, 2016January 31, 2027HORNER, STACY MICHELLEreporter.nih.gov
Development of polymeric synthetic biomaterial IP-001 to potentiate asystemic immunotherapy of hepatocellular carcinoma via thermal ablationNIHNational Cancer Institute2021 to 2024$2,400,000August 16, 2021August 31, 2025LAM, SIU KITreporter.nih.gov
Biomarkers of Alcoholic HepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,386,096June 1, 2020May 31, 2026ARTEEL, GAVIN Ereporter.nih.gov
Quantitative MRI and Deep Learning Technologies for Classification of NAFLDNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,364,000August 1, 2022April 30, 2027WU, HOLDEN Hreporter.nih.gov
Kentucky Outreach Service Kiosk (KyOSK): Reducing Overdose, Hepatitis C, and Other Drug-related Risks in Rural Appalachia through Health KiosksNIHNational Institute on Drug Abuse2022 to 2025$2,359,307August 15, 2022June 30, 2027YOUNG, APRIL MARIEreporter.nih.gov
Disparities in the Diffusion of Direct-Acting Antiviral Therapy for Hepatitis C among Baby Boomers: A Mixed-Methods StudyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,331,243August 1, 2020June 30, 2025SHAPIRO, MARTIN F.reporter.nih.gov
Heat shock protein 90 in alcoholic liver disease: targeting macrophage FunctionNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$2,330,377August 1, 2009June 30, 2027MANDREKAR, PRANOTIreporter.nih.gov
Adipsin in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,324,625July 1, 2022April 30, 2027PAJVANI, UTPALreporter.nih.gov
Hepatocyte-derived extracellular vesicles in alcoholic liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,324,384July 1, 2020March 31, 2026FELDSTEIN, ARIELreporter.nih.gov
The role of IL-17 signaling in alcohol-induced HCCNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,322,600August 6, 2021May 31, 2027KISSELEVA, TATIANAreporter.nih.gov
Predicting outcomes in nonalcoholic steatohepatitis with advanced fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,310,512September 15, 2022June 30, 2027SANYAL, ARUN Jreporter.nih.gov
A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver diseaseNIHNational Center for Advancing Translational Sciences2022 to 2024$2,306,928July 15, 2020June 30, 2026TAYLOR, D. LANSINGreporter.nih.gov
Small molecule antagonists targeting EphB receptors for the treatment of nonalcoholic steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,297,570August 1, 2021May 31, 2026MIMCHE, PATRICEreporter.nih.gov
Integrated analysis of HBV-specific CD4 T cell and B cell responses to define their role in chronic hepatitis B and HBV functional cure.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,286,418July 1, 2024May 31, 2029LAUER, GEORG MICHAELreporter.nih.gov
Rip Proteins in Innate Immune SignalingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,272,136December 15, 2008August 31, 2025KELLIHER, MICHELLE ALICEreporter.nih.gov
Evaluation of a persuasive health communication intervention designed to increase HIV/HCV screening among emergency departments patients who currently, formerly or never injected drugsNIHNational Institute on Drug Abuse2022 to 2024$2,264,864September 30, 2022July 31, 2027MERCHANT, ROLAND Creporter.nih.gov
HDAC1 as a nutrient sensor in the development and progression of NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,254,125June 3, 2022March 31, 2027SHI, HANGreporter.nih.gov
Mechanisms of hepatitis B virus cccDNA formationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,246,607May 15, 2020April 30, 2025PLOSS, ALEXANDERreporter.nih.gov
Control of Lipogenesis and Hepatic Steatosis by Caspase-2NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,246,301March 15, 2019November 30, 2025KARIN, MICHAELreporter.nih.gov
Fibrogenesis Targeted Manganese Based MRI Contrast AgentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$2,239,969September 15, 2022August 31, 2025HOFFMAN, VERAreporter.nih.gov
Integrated Care for Addiction, HIV and HCV Research and Education (ICAHRE)NIHNational Institute on Drug Abuse2021 to 2025$2,234,611July 1, 2017June 30, 2027STEIN, MICHAEL Dreporter.nih.gov
Rural Comorbidity and HIV consequences of Opioid use Research and Treatment Initiative (Rural cohort)NIHNational Institute on Drug Abuse2021 to 2023$2,227,803April 1, 2019March 31, 2026CRANE, HEIDI M.reporter.nih.gov
New insights into the functional diversity of the hepatic antiviral T cell response during hepacivirus infection in vivoNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,227,294June 1, 2022May 31, 2027BILLERBECK, EVAreporter.nih.gov
Development of a host-targeted antiviral as a chronic hepatitis B therapeutic with potential to achieve a functional cureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,223,594August 20, 2021June 30, 2027REMISZEWSKI, STACYreporter.nih.gov
Novel mechanism based treatment to improve tissue injury in alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,223,387September 25, 2020July 31, 2025DASARATHY, SRINIVASANreporter.nih.gov
Southern Liver Health CohortNIHNational Cancer Institute2021 to 2022$2,219,249September 21, 2021August 31, 2023HOYO, CATHRINEreporter.nih.gov
Understanding the metabolic pathology of pediatric obesity and NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,218,267April 22, 2022January 31, 2027SHORT, KEVIN R.reporter.nih.gov
Mechanistic function of HCV NS5A targeted by the potent inhibitorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,218,100February 1, 2020January 31, 2026YI, MINKYUNGreporter.nih.gov
Mechanisms of Hepadnavirus Assembly and ReplicationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,212,330February 15, 1999August 31, 2028HU, JIANMINGreporter.nih.gov
Systemic immunoregulatory consequences of bacterial translocation during health and diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,209,196September 21, 2021June 30, 2026MEISEL, MARLIESreporter.nih.gov
Etiology of Persistent Microalbuminuria in NigeriaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,202,068July 1, 2021May 31, 2026WESTER, C. WILLIAMreporter.nih.gov
Ex-vivo bioengineered technology to unravel dysfunction due to non-alcoholic steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,201,102July 1, 2023April 30, 2027WERTHEIM, JASON Areporter.nih.gov
Estimating the population size of persons who inject drugs in New YorkNIHNational Institute on Drug Abuse2021 to 2022$2,200,197June 1, 2021December 13, 2022BRADLEY, HEATHERreporter.nih.gov
Role of heat shock transcription factor HSF1 in tumorigenesisNIHNational Cancer Institute2021 to 2025$2,193,704July 1, 1996January 31, 2027MIVECHI, NAHID Freporter.nih.gov
Insulin Regulation of Hepatic Function via Zone-Specific Transcriptional ProgramsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,193,363May 1, 2021April 30, 2027BIDDINGER, SUDHA Breporter.nih.gov
HBV-specific T cell immunity in HBV/HIV coinfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,189,677August 1, 2025July 31, 2028VINIKOOR, MICHAEL JEFFREYreporter.nih.gov
RECK regulation of NASH and fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,185,559May 15, 2022April 30, 2027RECTOR, RANDY SCOTTreporter.nih.gov
Lipotoxicity and Liver InflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,182,776April 15, 2020February 29, 2028IBRAHIM, SAMARreporter.nih.gov
Therapeutic Mitochondrial UncouplersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,181,641May 1, 2021December 31, 2025SANTOS, WEBSTER Lreporter.nih.gov
Understanding the Multilevel Drivers of Liver Cancer DisparitiesNIHNational Cancer Institute2021 to 2023$2,174,412August 16, 2019July 31, 2025SHARIFF-MARCO, SALMAreporter.nih.gov
Integrative Liver Cell CoreNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,169,055June 15, 2001May 31, 2027TSUKAMOTO, HIDEKAZUreporter.nih.gov
Impaired VLDL secretion in progression of NAFLD and NASH in mice and humansNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,167,149July 16, 2019June 30, 2028DAVIDSON, NICHOLAS O.reporter.nih.gov
Exosomal biomarkers for the early detection of hepatocellular carcinomaNIHNational Cancer Institute2023 to 2025$2,166,339August 8, 2023July 31, 2028GOEL, AJAYreporter.nih.gov
Dihydroceramide Desaturase-1 Inhibitors for Treatment of Diabetes and Other Metabolic DiseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$2,139,998September 11, 2017August 31, 2024BLITZER, JEREMYreporter.nih.gov
The Saint Louis University Component of the NASH Clinical Research NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,135,402May 20, 2002June 30, 2027NEUSCHWANDER-TETRI, BRENT Areporter.nih.gov
Mechanisms of microcystin-induced hepatocellular carcinoma in nonalcoholic steatohepatitisNIHNational Institute of Environmental Health Sciences2021 to 2025$2,132,242January 19, 2021October 31, 2026CLARKE, JOHN DANIELreporter.nih.gov
A Role for the Novel HAF-NFkappaB Axis in Driving Obesity-Associated Liver CancerNIHNational Cancer Institute2022 to 2025$2,131,677September 1, 2025August 31, 2027KOH, MEI YEEreporter.nih.gov
Ketone Body Metabolism and Integrated Metabolic HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,128,893August 5, 2011June 30, 2025CRAWFORD, PETER Areporter.nih.gov
A novel approach to treat non-alcoholic steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,122,291June 1, 2021July 31, 2024ARBEENY, CYNTHIAreporter.nih.gov
Toxic lipid intermediate accumulation and cobalamin depletion promote AHR-mediated hepatotoxicity and the progression of non-alcoholic fatty liver disease (NAFLD)-like pathologiesNIHNational Institute of Environmental Health Sciences2022 to 2025$2,117,038September 1, 2025August 31, 2027ZACHAREWSKI, TIMOTHY R.reporter.nih.gov
Epidemiology of diet, metabolism and non-alcoholic fatty liver disease in Hispanic/Latino adultsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,113,449September 15, 2023July 31, 2027KAPLAN, ROBERT Creporter.nih.gov
Microbiome and Intestinal Innate Immune Response in Alcoholic Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,112,911September 25, 2011June 30, 2026SCHNABL, BERND G.reporter.nih.gov
Structural characterization of native HBV capsids and virions from human cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,112,197June 14, 2023May 31, 2028WANG, JOSEPH CHE-YENreporter.nih.gov
Assessing performance of a Hepatitis C Emergency Department (HepC-END) Screening ToolNIHNational Institute on Drug Abuse2023 to 2025$2,102,922September 15, 2023July 31, 2028PARK, HAESUKreporter.nih.gov
Mechanisms underlying hepatic immune cell recruitment in nonalcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,092,488April 1, 2021March 31, 2027RAEMAN, REBENreporter.nih.gov
TNF alpha and Recovery from Alcoholic Liver InjuryNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,088,463May 5, 2025April 30, 2030DIEHL, ANNA MAE ELIZABETHreporter.nih.gov
Pathobiology of Liver InjuryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,077,361September 23, 2016August 31, 2026MALHI, HARMEETreporter.nih.gov
Responding to the Increase in Substance Use, HIV, HCV, and Overdose in New England (RISE-NE)NIHNational Institute on Drug Abuse2025$2,076,525August 15, 2025May 31, 2030BAZZI, ANGELA ROBERTSONreporter.nih.gov
Cholesterol toxicity in alcohol-associated hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$2,069,392May 15, 2023April 30, 2028JIANG, ZHENGHUI GORDONreporter.nih.gov
Role of alcohol adapted Kupffer cells in the progression and resolution of ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,068,172September 27, 2000February 29, 2028WEINMAN, STEVEN Areporter.nih.gov
Synergistic effects of ECM and heterotypic crosstalk on cellular responses in non-alcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,068,034February 8, 2018June 30, 2027KHETANI, SALMAN Rreporter.nih.gov
A novel cholinergic circuitry in alcoholic liver disease (NIAAA)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,066,485March 15, 2021January 31, 2027WU, JUNreporter.nih.gov
Critical Lipid Species in the Hepatovirus LifecycleNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,065,233December 12, 2019May 31, 2025LEMON, STANLEY M.reporter.nih.gov
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile ImmunityNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,065,107August 23, 2023July 31, 2027MILICH, DAVID R.reporter.nih.gov
A novel pathway controls liver injury in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,058,572June 23, 2022March 31, 2027ZHAO, PENGreporter.nih.gov
Nonalcoholic Fatty Liver Disease (NAFLD) in Polycystic Ovary Syndrome: The Role of Androgens on Liver Injury and NAFLD ProgressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,051,810September 1, 2023June 30, 2028SARKAR, MONIKAreporter.nih.gov
Genetic Viral and Host Adaptations to Breach Species Barriers of HCVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,049,912July 1, 2013December 31, 2028PLOSS, ALEXANDERreporter.nih.gov
Elimination of HCV and related liver disease among HIV-infected and -uninfected people who inject drugsNIHNational Institute on Drug Abuse2021 to 2023$2,039,441January 15, 2019December 31, 2025THOMAS, DAVID Lreporter.nih.gov
Evaluating risk factors for cirrhosis progression and response to statin therapy among a cohort of patients with cirrhosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,035,766September 22, 2021July 31, 2027GOLDBERG, DAVID SETHreporter.nih.gov
Optimizing SWELL1 modulators to treat non-alcoholic steatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$2,035,065September 16, 2020August 31, 2025LERNER, DANIEL Jreporter.nih.gov
Hepatic TGFbeta1 in Control of Type 2 Diabetes and NASH via FoxO1 SignalingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,019,371December 1, 2021November 30, 2026GUO, SHAODONGreporter.nih.gov
Development of caspase-6 inhibitors for treatment of NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,016,023January 1, 2023November 30, 2027SALTIEL, ALAN R.reporter.nih.gov
Candidate selection of a LPAR1 antagonist for therapeutic application in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$2,013,280September 20, 2021June 30, 2026TUCCI, FABIO COHENreporter.nih.gov
Microchip for HBV testing using HIV-infected blood samplesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,012,162February 6, 2023November 30, 2024SHAFIEE, HADIreporter.nih.gov
Mechanisms of insulin resistance related to nonalcoholic steatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,007,393March 9, 2015March 31, 2025CZECH, MICHAEL Preporter.nih.gov
Estimating the cost of peer specialists providing comprehensive healthcare services at a syringe services programNIHNational Institute on Drug Abuse2023 to 2025$2,007,015June 1, 2023March 31, 2028TOOKES, HANSEL EMORYreporter.nih.gov
Role of SMPDL3B in obesity-associated non-alcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,006,588July 1, 2022April 30, 2027WANG, SHUXIAreporter.nih.gov
Imaging Hepatic Energy Metabolism in NAFLD/NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,004,135April 1, 2022December 31, 2026MERRITT, MATTHEW Ereporter.nih.gov
Interstitial Chemophototherapy with Light-Activated Nanoparticulate DoxorubicinNIHNational Cancer Institute2022 to 2023$2,000,000April 6, 2020July 31, 2025SHAFIRSTEIN, GALreporter.nih.gov
Rapid point-of-care molecular test for HCV VLNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,996,224September 1, 2021March 31, 2027FISHER, JAY KENNETHreporter.nih.gov
Leveraging the plasma virome as a biological indicator of HIV risk and transmission networks among people who inject drugsNIHNational Institute on Drug Abuse2023 to 2025$1,994,072June 1, 2023March 31, 2028KANDATHIL, ABRAHAMreporter.nih.gov
Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,986,219January 20, 2019December 31, 2025MCCLAIN, DONALD A.reporter.nih.gov
Developing and Automating an Extracellular Vesicle-Based Test for Early Detection of Hepatocellular CarcinomaNIHNational Cancer Institute2023 to 2025$1,984,827September 14, 2023August 31, 2026TSENG, HSIAN-RONGreporter.nih.gov
Adoptive MHC-E-Restricted T Cell Therapy for the Treatment of Chronic Hepatitis B Virus InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,982,398June 1, 2019May 31, 2024BURWITZ, BENJAMIN Jreporter.nih.gov
Understanding and Improving the Effectiveness of Public Health Laboratory Networks for Infectious Diseases in GhanaNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,975,313March 11, 2019February 28, 2025SCHROEDER, LEE FREDERICKreporter.nih.gov
A renewable and genetically tractable human stem cell-derived multicellular platform for the study of fibrotic liver diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,974,527March 1, 2021February 28, 2025RICE, CHARLES Mreporter.nih.gov
Peer-based Retention of people who Use Drugs in Rural Research (PROUD-R2)NIHNational Center for Advancing Translational Sciences2021 to 2023$1,971,059September 18, 2018July 31, 2024KORTHUIS, PHILIP TODDreporter.nih.gov
Human mechanisms of virus persistence in an AAV-based mouse model of chronic HBV infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,966,264May 6, 2020April 30, 2026ROBEK, MICHAELreporter.nih.gov
Click Chemistry-Mediated Surface Protein Assay for Quantifying Subpopulations of Hepatocellular Carcinoma-associated Extracellular VesiclesNIHNational Cancer Institute2023 to 2025$1,964,033July 1, 2023June 30, 2028ZHU, YAZHENreporter.nih.gov
Mass spectrometry for highly sensitive and sample-sparing analysis of extracellular vesicles in liver diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,963,066August 1, 2023May 31, 2027REVZIN, ALEXANDERreporter.nih.gov
Hepatic stellate cells in NASH fibrosis and HCCNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,960,030April 1, 2021March 31, 2025FRIEDMAN, SCOTT L.reporter.nih.gov
A Precision Medicine for Alcohol-Associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$1,959,401September 20, 2023August 31, 2025LIU, WANQINGreporter.nih.gov
San Diego Cirrhosis Clinical Research NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,949,305September 9, 2021July 31, 2027LOOMBA, ROHITreporter.nih.gov
Molecular Mechanisms of HBV cccDNA FormationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,933,309March 11, 2016June 30, 2027GUO, HAITAOreporter.nih.gov
Developing a renewable and dissectible human liver for the study of HBV/HCV infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,932,000August 18, 2022July 31, 2027WU, XIANFANGreporter.nih.gov
LXR-Dependent Cholesterol SensingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,928,942April 1, 2022June 30, 2026SCHULMAN, IRA Greporter.nih.gov
Maternal effect on offspring immunity against hepatitis B virusNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,925,049July 3, 2019June 30, 2025OU, J.-H. JAMESreporter.nih.gov
Sphingosine kinase 2 in sexual dimorphism of hepatocellular carcinomaNIHNational Cancer Institute2022 to 2025$1,923,553September 1, 2022August 31, 2027GREEN, CHRISTOPHER Dreporter.nih.gov
Dissecting the NRG4 hormonal checkpoint in metabolic liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,912,088July 15, 2015June 30, 2025LIN, JIANDIE Dreporter.nih.gov
Inhibition of EGF Receptor Prevents and Reverses Non-Alcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,893,133February 3, 2021January 31, 2026MICHALOPOULOS, GEORGE Kreporter.nih.gov
The UW Medical Student Addiction Research (MedStAR) Program to Address Substance Use and Disorders in Urban and Rural Communities in Five Western StatesNIHNational Institute on Drug Abuse2021 to 2025$1,882,544May 1, 2020April 30, 2030TSUI, JUDITHreporter.nih.gov
Role of HCV exosomes in intercellular communicationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,877,240April 15, 2020February 28, 2026HAHN, YOUNG S.reporter.nih.gov
Modeling Viral and T Lymphocyte DynamicsNIHOffice of the Director, National Institutes of Health2021 to 2024$1,866,528December 23, 2019November 30, 2025PERELSON, ALAN Sreporter.nih.gov
Mechanisms of HBV Functional Cure During Tenofovir-based ART in HIV/HBV CoinfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,857,031September 1, 2019August 31, 2025VINIKOOR, MICHAEL JEFFREYreporter.nih.gov
Pre-clinical Validation of A Novel Protein Drug Candidate for ASH and NASH TreatmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,843,194September 1, 2021June 30, 2025YANG, JENNY J.reporter.nih.gov
Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)NIHNational Institute on Drug Abuse2021 to 2022$1,836,801August 15, 2017July 31, 2023PHO, MAI TUYETreporter.nih.gov
Testing of Drug Combinations For Mycobacterium tuberculosis (MTB) in MiceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,831,148September 1, 2022November 30, 2025SLAYDEN, RICHARDreporter.nih.gov
Novel pathways in the pathogenesis and pathophysiology of NAFLD in HispanicsNIHNational Institute on Minority Health and Health Disparities2021 to 2023$1,820,623March 12, 2019November 30, 2024NAJJAR, SONIA M.reporter.nih.gov
IRAKM and MINCLE in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,806,489August 17, 2023July 31, 2028NAGY, LAURA E.reporter.nih.gov
Harnessing the power of peer navigation and mHealth to reduce health disparities in AppalachiaNIHNational Institute of Nursing Research2021 to 2024$1,805,022August 27, 2020March 21, 2025RHODES, SCOTT Dreporter.nih.gov
Rapid, Point-of-Care Diagnostics for Hepatitis C VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,799,981August 12, 2022August 12, 2025UNGEWITTER, ERICAreporter.nih.gov
The pathophysiological function of PNPLA3-148M variant in alcohol-induced liver injuryNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$1,799,014May 1, 2022March 31, 2027DONG, X. CHARLIEreporter.nih.gov
USC Cirrhosis Clinical CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,796,054September 22, 2021July 31, 2027TERRAULT, NORAH A.reporter.nih.gov
Evaluation of anti-fibrotic and anti-inflammatory semi-synthetic oxysterol, Oxy210, as a therapeutic drug candidate for non-alcoholic steatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$1,786,691May 1, 2023April 30, 2026PARHAMI, FARHADreporter.nih.gov
Non-immunosuppressive Sanglifehrin Analogs as Therapeutic Agents for Viral Hepatitis-induced Liver Damage DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,783,750April 1, 2020March 31, 2026GALLAY, PHILIPPE ANDREreporter.nih.gov
In search of an HBV cure: novel model systems and targetsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,782,852June 10, 2019May 31, 2024RICE, CHARLES Mreporter.nih.gov
AlcHepNet DCC UMMSNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,781,820August 1, 2018June 30, 2024BARTON, BRUCE Areporter.nih.gov
UC San Diego Raising Advancement and Parity for Infectious Disease Researchers (RAPID) Faculty Development ProgramNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,778,757August 10, 2020July 31, 2030TREJO, JOANNreporter.nih.gov
Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)NIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$1,774,440May 1, 2014November 30, 2026YIN, MENGreporter.nih.gov
Transcriptional and non-transcriptional function of IRF3 in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,763,975July 5, 2019June 30, 2029NAGY, LAURA E.reporter.nih.gov
Mediators of fatty liver disease during HIV/SIV and cART treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,758,840February 19, 2018January 31, 2024SODORA, DONALD Lreporter.nih.gov
Notch, Type 2 Diabetes and NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,752,429July 1, 2015March 31, 2024PAJVANI, UTPALreporter.nih.gov
Pathobiology of Nonalcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,735,008September 30, 2021July 31, 2026HIRSOVA, PETRAreporter.nih.gov
1/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)NIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,732,406August 1, 2023July 31, 2030TERRAULT, NORAH A.reporter.nih.gov
Integrated therapies for alcohol use and ALD (ITAALD) Network - IU Clinical CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,707,981September 15, 2012June 30, 2029CHALASANI, NAGA Preporter.nih.gov
A new humanized mouse model to study HBV gene editingNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,705,880August 1, 2024July 31, 2029JEROME, KEITH Rreporter.nih.gov
PPARgamma-regulated mechanisms in hepatocytes that promote NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,702,743February 1, 2022January 31, 2027CORDOBA-CHACON, JOSEreporter.nih.gov
Hepatic TrkB-T1 signaling in NASH pathogenesis and resolutionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,695,001April 1, 2023January 31, 2027LIN, JIANDIE Dreporter.nih.gov
Hepatic mTORC1 Signaling and the Regulation of Lipid HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,694,012March 1, 2021January 31, 2025TITCHENELL, PAUL MICHAELreporter.nih.gov
A Precision Targeted Therapeutics for Nonalcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,693,379July 1, 2021April 30, 2026LIU, WANQINGreporter.nih.gov
Role of Screening and Early Intervention in Primary Care with Low-Dose Pioglitazone for Patients with T2DM and NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,689,302May 8, 2020February 28, 2026CUSI, KENNETHreporter.nih.gov
Matrix in pre-cirrhotic HCCNIHNational Cancer Institute2023 to 2025$1,687,806March 15, 2023February 29, 2028TOROK, NATALIE J.reporter.nih.gov
Role of Soluble Epoxide Hydrolase in Alcohol-Associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$1,662,196June 1, 2022March 31, 2027KIRPICH, IRINA A.reporter.nih.gov
Role of SAMe in the Progression of Nonalcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,656,555September 20, 2002June 30, 2026LU, SHELLY CHI-LOOreporter.nih.gov
Development of standardized immunoassays and virus panels for HCV vaccine researchNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,651,974July 23, 2021June 30, 2025BAILEY, JUSTIN RICHARDreporter.nih.gov
Role of Base Excision Repair in Limiting Hepatocellular CarcinomasNIHNational Institute of Environmental Health Sciences2021 to 2024$1,650,684January 1, 2020October 31, 2024LLOYD, R. STEPHENreporter.nih.gov
Autophagy and the Replication of Hepatitis B VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,650,000February 3, 2020January 31, 2026OU, J.-H. JAMESreporter.nih.gov
Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell ProliferationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,640,516August 20, 2024July 31, 2029MISHRA, LOPAreporter.nih.gov
Highly penetrant and immunogenic mouse models of non-viral HCC that are suitable for evaluation of immune checkpoint inhibitorsNIHNational Cancer Institute2021 to 2023$1,637,378December 1, 2018November 30, 2024KARIN, MICHAELreporter.nih.gov
Sulfur Amino Acid Metabolism and Regulation of Hepatic Metabolic FlexibilityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,632,006January 1, 2022December 31, 2025LI, TIANGANGreporter.nih.gov
Disturbed Crosstalk between Cholesterol Homeostasis and Inflammation Resolution in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,626,085May 1, 2023August 10, 2025CAI, BISHUANGreporter.nih.gov
Lipidated Amino Acids in Cardiometabolic DiseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,621,509June 2, 2022March 31, 2027ROM, ORENreporter.nih.gov
Developing Woodchucks Susceptible to Hepatitis B Virus Infection by Modifying the Virus or HostNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,621,356July 17, 2024June 30, 2029MENNE, STEPHANreporter.nih.gov
Glycopathology of HCC: identification of the source cells of serum fucosylationNIHNational Cancer Institute2021 to 2023$1,620,312March 14, 2019February 28, 2025MEHTA, ANAND S.reporter.nih.gov
Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular RiskNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,615,258May 15, 2018April 30, 2025STANLEY, TAKARA LEAHreporter.nih.gov
Alcohol-induced hepatotoxicity - implications of secretin/secretin receptor axisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,614,707September 5, 2020September 11, 2023ALPINI, GIANFRANCO Dreporter.nih.gov
Next generation quantitative HCV drug resistance assayNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,611,097March 1, 2018June 30, 2025WAGNER, RICHARDreporter.nih.gov
Hepatic insulin resistance integrates T2D and NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,593,841September 5, 2024July 31, 2028WHITE, MORRIS F.reporter.nih.gov
Animal Model to study heterogeneous outcomes of HCV Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,575,922June 1, 2024April 30, 2029KAPOOR, AMITreporter.nih.gov
Collaborative Justice-Involved Research and Training Program on Substance Use and HIV at Brown University HealthNIHNational Institute on Drug Abuse2021 to 2025$1,575,185June 1, 2014December 31, 2029BECKWITH, CURT Greporter.nih.gov
Development of Controlled Release Mitochondrial Protonophore (CRMP) as a Novel Treatment for Type-2 Diabetes and Non-Alcoholic Steatohepatitis in Dysmetabolic Non-Human PrimatesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,574,788March 15, 2019February 28, 2025SHULMAN, GERALD Ireporter.nih.gov
Altering Hepatitis B Virus assembly through pharmacological interventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,572,240May 6, 2020April 30, 2026GUMBART, JAMES C.reporter.nih.gov
Breaching the species barrier: Towards an immunocompetent HBV-susceptible mouse modelNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,568,998June 12, 2024May 31, 2029RICE, CHARLES Mreporter.nih.gov
Dissecting Hepatitis B Vaccine Adjuvant Effects on Immune Responses and the HIV Reservoir in PLWHNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,567,217July 25, 2024May 31, 2029COX, ANDREA Lreporter.nih.gov
Modeling immune impairments and pathogenesis in novel humanized mice for HBV-HIV co-infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,566,354September 24, 2018August 31, 2024SU, LISHANreporter.nih.gov
Long-acting Antiviral Treatment for HBVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,562,010July 10, 2024June 30, 2029HO, RODNEY J.Y.reporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD)- Cleveland Clinic Clinical CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,561,055August 1, 2018June 30, 2029DASARATHY, SRINIVASANreporter.nih.gov
Intestine FXR activation by LGG-derived nanoparticles in alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,559,904August 15, 2022May 31, 2027FENG, WENKEreporter.nih.gov
Mechanism for hepatitis E virus exit from polarized hepatocytesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,554,075March 14, 2023February 29, 2028FENG, ZONGDIreporter.nih.gov
Novel therapeutic approach for NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,553,952June 4, 2020May 31, 2025MAITRA, RANGANreporter.nih.gov
Changes in Bone Quality, Sarcopenia and Fat Distribution in HIV/HCV Patients after HCV TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,553,826December 1, 2017November 30, 2024LO RE, VINCENTreporter.nih.gov
Epigenetic Regulation of HBV cccDNA TranscriptionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,551,736June 16, 2020May 31, 2026GUO, HAITAOreporter.nih.gov
ANTIVIRAL DRUGS TO CURE CHRONIC HEPATITIS B VIRUS INFECTIONNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$1,549,999April 3, 2023August 25, 2025ZHANG, YANG-YUANreporter.nih.gov
HBV cccDNA transcriptional silencing with and without HIVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,548,735July 22, 2024May 31, 2029BALAGOPAL, ASHWINreporter.nih.gov
Linking fat metabolism to hepatic fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,547,010April 1, 2020March 31, 2024NAJJAR, SONIA M.reporter.nih.gov
NASH-associated macrophages: regulation and role in disease pathogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,545,379April 1, 2023January 31, 2027LIN, JIANDIE Dreporter.nih.gov
Protective role of OPN-High macrophages in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,545,316August 5, 2023May 31, 2027NIETO, NATALIAreporter.nih.gov
Determining hepatocyte-specific mechanisms by which Ube4A regulates NAFLD/NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,543,965March 15, 2023March 9, 2025CHAKRABORTY, ANUTOSHreporter.nih.gov
Axin Stabilization by Novel Small Molecules to Treat Non-alcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,541,402April 1, 2023January 31, 2028SHU, YANreporter.nih.gov
Roles of peroxisomal dysfunction in alcohol-related liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,538,891June 1, 2023February 29, 2028ZHONG, WEIreporter.nih.gov
Influence of integrant-derived HBV RNAs encoding the envelope proteins on HBV life cycleNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,537,333February 4, 2022January 31, 2027GUDIMA, SEVERIN Oreporter.nih.gov
Reducing Vertical Transmission of Hepatitis B in Africa (REVERT-B Trial)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,534,174May 18, 2020March 31, 2026DIONNE, JODIE ANNreporter.nih.gov
Engaging People Who Use Drugs in Harm Reduction Service Delivery: An Intravention to Reduce Risk of HIV, HCV, Overdose, and Injection-related Infections in Rural AppalachiaNIHNational Institute on Drug Abuse2024$1,533,697September 30, 2024August 31, 2026YOUNG, APRIL MARIEreporter.nih.gov
The Epidemiology of the Weiss Cohort ProjectNIHNational Institute on Drug Abuse2021 to 2022$1,531,257August 15, 2020June 30, 2023WEISS, STANLEY Hreporter.nih.gov
Point-of-care Nucleic Acid Amplification Test for pangenomic Hepatitis C diagnosis in outpatient clinicsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,528,985July 3, 2024May 31, 2029POSNER, JONATHAN Dreporter.nih.gov
O-glycoproteins in the progression of liver diseaseNIHNational Cancer Institute2021 to 2023$1,525,161July 1, 2019June 30, 2024GOLDMAN, RADOSLAVreporter.nih.gov
Molecular mechanisms of nucleic acid machinesNIHNational Institute of General Medical Sciences2021 to 2024$1,520,008June 1, 2020May 31, 2026ENEMARK, ERICreporter.nih.gov
Perfluoroalkyl Substances (PFASs) and Liver Cancer Risk in the United StatesNIHNational Cancer Institute2022 to 2023$1,519,485July 1, 2022February 29, 2024ZHANG, XUEHONGreporter.nih.gov
Cellular interactions between TGF-beta pathway members and epigenetic regulators in liver and gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$1,518,039July 18, 2018March 31, 2029MISHRA, LOPAreporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Virginia Commonwealth UniversityNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,515,775August 1, 2018June 30, 2029ARAB, JUAN PABLOreporter.nih.gov
The Role of ERRa in liver lipid dysfunction and pathologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,515,199December 1, 2021November 30, 2026STILES, BANGYANreporter.nih.gov
HBV RNaseH inhibitors: Effects on HBV biology and resistance developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,515,000December 2, 2019November 30, 2025TAVIS, JOHN Ereporter.nih.gov
A hepatocyte-specific R-spondin mimetic bispecific fusion protein to stimulate hepatocyte regeneration in patients with acute alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,512,500September 25, 2020June 3, 2024TIBBITTS, JAYreporter.nih.gov
Building on Needle Exchange to Optimize HIV Prevention/TreatmentNIHNational Institute on Drug Abuse2021 to 2022$1,506,924September 15, 2017March 31, 2025LUCAS, GREGORY Mreporter.nih.gov
Alcohol and Monocyte Signaling Administrative SupplementNIHNational Institute on Alcohol Abuse and Alcoholism2024 to 2025$1,506,751April 1, 1998March 31, 2029SZABO, GYONGYIreporter.nih.gov
SBIR PHASE II Point-of-Care HCV DetectionNIHNational Institute of Allergy and Infectious Diseases2023$1,500,000September 15, 2023September 14, 2026QI, HONGreporter.nih.gov
Development of a hamster model for hepatitis B virus infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,485,242August 9, 2024July 31, 2029WANG, ZHONGDEreporter.nih.gov
Hepatitis B virus e antigen in viral persistenceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,485,000February 20, 2017January 31, 2028OU, J.-H. JAMESreporter.nih.gov
Multimode Observation of Virus Capsid AssemblyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,480,293March 14, 2016July 31, 2027ZLOTNICK, ADAMreporter.nih.gov
The Epidemiology of the Weiss Cohort ProjectNIHNational Institute on Drug Abuse2023 to 2025$1,471,222August 15, 2020June 30, 2027WEISS, STANLEY Hreporter.nih.gov
Integrated therapies for alcohol use and ALD (ITAALD) Network – UTSW Clinical CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,469,096August 1, 2018June 30, 2029MITCHELL, MACK CLARENCEreporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) – Mayo ClinicNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,459,312August 1, 2018June 30, 2029SHAH, VIJAY H.reporter.nih.gov
Mechanisms linking the Branched-Chain alpha-Keto Acid regulatory network to the pathogenesis of NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,457,604April 15, 2023January 31, 2028WHITE, PHILLIP Jreporter.nih.gov
Exploiting Natural Killer cells in HIV/HBV co-infection to achieve eradicationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,455,547July 9, 2020June 30, 2026PEPPA, DIMITRAreporter.nih.gov
Identification of the Exposome in Fatty Liver Disease in Mexican American Families Using Genetic CorrectionNIHNational Institute on Minority Health and Health Disparities2021 to 2022$1,454,720April 27, 2018November 30, 2024BLANGERO, JOHNreporter.nih.gov
Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitorsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$1,450,638September 25, 2018August 31, 2024KARIN, MICHAELreporter.nih.gov
Clinical Research Network in Nonalcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,447,477July 1, 2002June 30, 2027KOWDLEY, KRISreporter.nih.gov
Renal Disposition in NASHNIHNational Institute of Environmental Health Sciences2021 to 2023$1,446,306February 1, 2019January 31, 2025CHERRINGTON, NATHAN Jreporter.nih.gov
Pharmacologic targeting of the UPR in obesity-linked liver dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,443,302January 15, 2024November 30, 2027SAEZ, ENRIQUEreporter.nih.gov
Oregon HIV/Hepatitis and Opioid Prevention and Engagement (OR-HOPE) Study Cost ExtensionNIHNational Institute on Drug Abuse2021 to 2022$1,441,353August 15, 2017July 31, 2023KORTHUIS, PHILIP TODDreporter.nih.gov
Universal HCV screening in pregnancy: Examining testing uptake and HCV careNIHNational Institute on Drug Abuse2024 to 2025$1,439,607September 30, 2024July 31, 2029KAPADIA, SHASHIreporter.nih.gov
Liver lobule zonation, hepatocellular carcinoma (HCC) and β-catenin mediated hepatitis B virus (HBV) biosynthesisNIHNational Cancer Institute2021 to 2024$1,430,166December 1, 2019November 30, 2025MCLACHLAN, ALANreporter.nih.gov
Perfluoroalkyl Substances (PFASs) and Liver Cancer Risk in the United StatesNIHNational Cancer Institute2024 to 2025$1,426,107July 1, 2022June 30, 2027ZHANG, XUEHONGreporter.nih.gov
Role of Interferon-Gamma / Interleukin-12 Axis in Metabolic Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,424,427July 1, 2023April 30, 2027KIM, JASON Kreporter.nih.gov
Predict, Detect, Diagnose: Confronting Outbreaks of HIV and Other Infectious Diseases Among People Who Use DrugsNIHNational Institute on Drug Abuse2024 to 2025$1,422,136September 1, 2024May 31, 2029GONSALVES, GREGG STEVENreporter.nih.gov
Estimating the population size of persons who inject drugs in New YorkNIHNational Institute on Drug Abuse2023 to 2024$1,422,069October 1, 2022January 31, 2026BRADLEY, HEATHERreporter.nih.gov
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)NIHNational Institute on Drug Abuse2021 to 2022$1,415,827August 15, 2017July 31, 2023YOUNG, APRIL MARIEreporter.nih.gov
Intestinal Barrier, Probiotic Bacteria, and the Gut-Liver AxisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,415,174March 18, 2019December 31, 2024MA, THOMAS Yreporter.nih.gov
Dynamics of antigen specific B and Tfh responses during acute and chronic HCVNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,411,254December 13, 2017November 30, 2024GRAKOUI, ARASHreporter.nih.gov
Determinants of immunotherapy response in NASH-Hepatocellular carcinomaNIHNational Cancer Institute2023 to 2025$1,408,891August 4, 2023July 31, 2028LLOVET, JOSEP Mreporter.nih.gov
Hepatic fat accumulation in nonalcoholic fatty liver disease: critical regulation by kisspeptin signalingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,408,849April 30, 2022March 31, 2027BHATTACHARYA, MOSHMI Mreporter.nih.gov
Cell surface receptors promoting hepatitis B virus infectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,406,502July 15, 2020April 30, 2024LUO, GUANGXIANG GEORGEreporter.nih.gov
Integrating low-cost and versatile technologies to achieve colorimetric HCV and HIV detection from whole bloodNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,401,526August 15, 2024June 30, 2029MYERS, DAVID RICHARDreporter.nih.gov
Integrated therapies for alcohol use and ALD (ITAALD) Network -UofL Clinical CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,401,448August 1, 2018June 30, 2029MCCLAIN, CRAIG J.reporter.nih.gov
Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,386,143May 1, 2002June 30, 2027DIEHL, ANNA MAE ELIZABETHreporter.nih.gov
Transcription cycle regulation by nutrientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,382,190July 15, 2022April 30, 2027MORRAL, NURIAreporter.nih.gov
A proteomics atlas of HIV/HBV infections for curing HBVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,381,244August 1, 2024June 30, 2029MICHAILIDIS, ELEFTHERIOSreporter.nih.gov
Targeting hepatic mitochondrial oxidation to treat NAFLD, NASH and type 2 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,375,819January 18, 2024December 31, 2028SHULMAN, GERALD Ireporter.nih.gov
Novel mouse models of hepatitis B virus infection and replicationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,373,666June 21, 2024April 30, 2029LUO, GUANGXIANG GEORGEreporter.nih.gov
Hepatitis C Virus Trafficking in HepatocytesNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,372,358March 5, 2019February 28, 2025RANDALL, GLENN Creporter.nih.gov
SELECTION OF VACCINE ANTIGENS FOR PROTECTION FROM HEPATITIS C VIRUS INFECTIONNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,349,865July 1, 2020April 30, 2026RAY, RANJITreporter.nih.gov
Development of a Machine Learning Model to Integrate Clinical, Laboratory, Sonographic, and Elastographic Data for Noninvasive Liver Tissue Characterization in NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,345,263January 20, 2019December 31, 2025SAMIR, ANTHONY EDWARDreporter.nih.gov
Project ACCESS: Advancing Access to HIV/HCV Testing Through Transformation in Syringe Services Programs: A Cluster Randomized TrialNIHNational Institute on Drug Abuse2024 to 2025$1,343,426July 1, 2024April 30, 2029BARTHOLOMEW, TYLER SCOTTreporter.nih.gov
Liver fibrosis cell-based assay platform: integrating patient-derived fibrotic liver ECM with primary stellate cells, Kupffer cells, and hepatocytes to accelerate anti-fibrotic drug developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,337,735September 1, 2024August 31, 2027O'NEILL, JOHN DAVIDreporter.nih.gov
Viral Determinants of Chronic Hepacivirus InfectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,331,080June 1, 2024April 30, 2029KAPOOR, AMITreporter.nih.gov
Dissecting the Intracellular and Extracellular Role of TREM2 in the Pathogenesis of Non-Alcoholic Steatohepatitis.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,326,264August 15, 2023June 30, 2027DHAR, DEBANJANreporter.nih.gov
2/4-The INTEGRATE Study: Evaluating INTEGRATEd care to Improve Biopschosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,314,963August 1, 2023July 31, 2030VERNA, ELIZABETH CLARICEreporter.nih.gov
Molecular Mechanisms by which Statins Prevent and Reverse Hepatocellular CarcinomaNIHNational Cancer Institute2023 to 2025$1,310,295September 19, 2023August 31, 2027FELSHER, DEAN Wreporter.nih.gov
Sympathetic circadian dysfunction in obesity-related hepatocarcinogenesisNIHNational Cancer Institute2021 to 2023$1,308,596September 1, 2019August 31, 2025FU, LONING NONEreporter.nih.gov
Hepatitis B virus integrations in KMT2B drive hepatocellular carcinomaNIHNational Cancer Institute2023 to 2025$1,297,237July 15, 2022June 30, 2027CAO, JIANreporter.nih.gov
T cells in HCV/HIV co-infectionNIHNational Institute on Drug Abuse2021 to 2022$1,296,998March 1, 2018December 31, 2023LAUER, GEORG MICHAELreporter.nih.gov
Molecular mechanisms of post-transplant recurrent alcoholic liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,286,113September 10, 2017March 31, 2028CARR, ROTONYA Mreporter.nih.gov
1/4-The INTEGRATE Study: Evaluating INTEGRATEd Care to Improve Biopsychosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,276,071August 1, 2023July 31, 2030VANWAGNER, LISA Breporter.nih.gov
Modeling and Characterization of NAFLD Phenotypes in a Severely Affected FamilyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,272,904February 1, 2024November 30, 2027MATTIS, ARAS NIKODEMASreporter.nih.gov
Dysregulated Oxalate Metabolism in Cardiometabolic DiseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,269,041August 5, 2023May 31, 2027ROM, ORENreporter.nih.gov
Collaborative Clinical Research in Nonalcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,268,720May 20, 2002June 30, 2027CHALASANI, NAGA Preporter.nih.gov
Mitochondrial DAMPs-driven Mechanisms of Liver Fibrosis in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,267,548April 1, 2024January 31, 2028POPOV, YURYreporter.nih.gov
TARGETING MASH WITH NOVEL SMALL MOLECULE TXNIP INHIBITORNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,264,958August 1, 2024May 31, 2029SHALEV, ANATHreporter.nih.gov
Reducing morbidity and mortality from overdose, HIV, and hepatitis C in opioid-using personsNIHNational Institute on Drug Abuse2021 to 2022$1,262,543September 1, 2018June 30, 2024BRAITHWAITE, RONALD SCOTTreporter.nih.gov
Role of Human Apolipoprotein E in Hepatitis B Virus Infection and MorphogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,261,056September 22, 2020August 31, 2024LUO, GUANGXIANG GEORGEreporter.nih.gov
Helicobacter Infection and Liver Cancer Risk among African Americans and Whites in the United StatesNIHNational Cancer Institute2021 to 2023$1,249,102July 16, 2021February 29, 2024ZHANG, XUEHONGreporter.nih.gov
Multiparametric ultrasound imaging for early detection of nonalcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,245,041December 21, 2020July 31, 2023HOYT, KENNETHreporter.nih.gov
Collaborative Integration of Hepatitis B Molecular Virology and Mathematical/Computational ModelingNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,242,317January 15, 2019June 30, 2025UPRICHARD, SUSAN L.reporter.nih.gov
HIV, HCV, Hippo, and Liver Disease ProgressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,239,696November 3, 2017October 31, 2024CHUNG, RAYMOND Treporter.nih.gov
Mechanisms of Early-life Immunity Associated with HIV-1 Vaccine-induced Neutralizing Antibody ResponsesNIHNational Institute of Allergy and Infectious Diseases2025$1,239,565August 20, 2025June 30, 2030WILLIAMS, WILTON Breporter.nih.gov
Persistent hepatitis C virus replication and immunity in pregnancyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,233,787February 1, 2012May 31, 2025WALKER, CHRISTOPHER M.reporter.nih.gov
Regulation of the pro-fibrotic connective tissue growth factor in alcoholic liver disease: mechanisms and targeting approachesNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$1,233,061February 1, 2020January 31, 2026PI, LIYAreporter.nih.gov
Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 StudyNIHNational Cancer Institute2024 to 2025$1,232,605September 3, 2024August 31, 2029KIRK, GREGORY Dreporter.nih.gov
Role of Fbxo48-mediated AMPK proteostasis in the pathogenesis and treatment of NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,232,144January 1, 2019December 31, 2024JURCZAK, MICHAEL J.reporter.nih.gov
Manipulation of lipid metabolism in (+)RNA virus replicationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,230,000June 7, 2023May 31, 2028RANDALL, GLENN Creporter.nih.gov
Cyanobacteria, cyanotoxins, and liver cancer developmentNIHNational Cancer Institute2024 to 2025$1,227,270May 1, 2024April 30, 2029HERNANDEZ, BRENDA YUKARIreporter.nih.gov
Exposome and Precision Medicine in NAFLDNIHNational Institute of Environmental Health Sciences2021 to 2022$1,217,227August 28, 2020July 31, 2025CAVE, MATTHEW Creporter.nih.gov
A Multi-site Multi-Setting RCT of Integrated HIV Prevention and HCV Care for PWIDNIHNational Institute on Drug Abuse2022$1,217,167September 30, 2017March 12, 2025METSCH, LISA Rreporter.nih.gov
Novel IP6K1 inhibitors for treatment of NAFLD/NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,215,396April 1, 2024January 31, 2028WANG, XIAODONGreporter.nih.gov
Hepatic Integration of Mitochondrial Oxidative Metabolism Pathways in Health and DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,214,419July 1, 2023April 30, 2028HUGHEY, CURTISreporter.nih.gov
Active HCV diagnosis to support prevention of HCC in LMICsNIHNational Cancer Institute2024 to 2025$1,208,204August 9, 2024July 31, 2029MCFALL, SALLY MAUREENreporter.nih.gov
Interleukin 33 Regulation for Cancer Prevention in Chronic InflammationNIHNational Cancer Institute2024 to 2025$1,208,126April 1, 2024March 31, 2029DEMEHRI, SHADMEHRreporter.nih.gov
2/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)NIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,205,015August 17, 2023July 31, 2030SERPER, MARINAreporter.nih.gov
A chicken model to study hepatitis E virus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,200,000June 15, 2002April 30, 2025MENG, XIANG-JINreporter.nih.gov
The role of hexokinase 2 in liver fibrosis and NASH-induced HCCNIHNational Cancer Institute2024 to 2025$1,194,448September 1, 2024August 31, 2029HAY, NISSIMreporter.nih.gov
Mechanisms Underlying the Pathogenesis of Non-alcoholic Fatty Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$1,193,434July 1, 2015August 31, 2024ZHANG, YANQIAOreporter.nih.gov
A Cluster RCT to Increase HIV Testing in Substance Use Treatment ProgramsNIHNational Institute on Drug Abuse2021$1,188,364September 1, 2016July 31, 2025METSCH, LISA Rreporter.nih.gov
3/4-The INTEGRATE Study: Evaluating INTEGRATEd Care to Improve Biopsychosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,185,356August 10, 2023July 31, 2030GOLDBERG, DAVID SETHreporter.nih.gov
Epitranscriptomic regulation of HBV gene expressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,184,583March 1, 2019February 29, 2024SIDDIQUI, ALEEMreporter.nih.gov
Quantitative characterization of the liver-pancreas axis in diabetes via multiparametric magnetic resonance elastographyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,181,482August 9, 2023April 30, 2028YIN, MENGreporter.nih.gov
Development and Preclinical Evaluation of Nanoformulations in Liver Fibrotic MiceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,177,172April 1, 2023February 29, 2028MAHATO, RAM I.reporter.nih.gov
Developmental regulation of HBV biosynthesis by Ten-eleven translocation (Tet) methylcytosine dioxygenasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,173,588June 9, 2023May 31, 2028MCLACHLAN, ALANreporter.nih.gov
AhR-dependent Pkm2 regulation in NAFLD progressionNIHNational Institute of Environmental Health Sciences2021 to 2023$1,171,441April 1, 2019March 31, 2025ZACHAREWSKI, TIMOTHY R.reporter.nih.gov
Development of delivery methods for combination microRNA treatment of alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,167,111July 1, 2019June 30, 2025OUPICKY, DAVIDreporter.nih.gov
3/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)NIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,166,224August 17, 2023July 31, 2030LUCEY, MICHAEL RONANreporter.nih.gov
Testing of a Novel Inhaled Clofazimine (CFZ) Dry Powder Formulation in a Mouse Model of Mycobacterium tuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,164,080August 1, 2023June 30, 2025ENDSLEY, JANICEreporter.nih.gov
Mechanisms regulating lipoprotein secretion and lipid metabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,157,766January 1, 2023December 31, 2026NI, HONGMINreporter.nih.gov
Oral digoxin for the treatment of NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,157,605March 15, 2024January 31, 2029BANINI, BUBU AMAreporter.nih.gov
RNA m6A methylation contributes to hepatic inflammation in obesity-associated NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,156,109March 1, 2023December 31, 2026OUYANG, XINSHOUreporter.nih.gov
Effects of State Laws to Reduce Opioid Diversion on Transitions to Injection Drug Use and HIV/HCV TransmissionNIHNational Institute on Drug Abuse2021 to 2022$1,137,366April 1, 2018December 31, 2023DICKSON-GOMEZ, JULIA Breporter.nih.gov
Role of CMA failure in NASH progression to Hepatocellular CarcinomaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,134,000May 1, 2020April 30, 2025ARIAS-PEREZ, ESPERANZAreporter.nih.gov
Drug Injection Surveillance and Care Enhancement for Rural Northern New England (DISCERNNE)NIHNational Institute on Drug Abuse2021 to 2022$1,131,736August 15, 2017July 31, 2023FRIEDMANN, PETER Dreporter.nih.gov
Structure-Based Vaccine Design for Hepatits C VirusNIHNational Institute of Allergy and Infectious Diseases2021$1,120,994June 1, 2017May 31, 2023FUERST, THOMAS Rreporter.nih.gov
Impact of HIV co-infections and comorbidities on circadian rhythm in the liverNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,120,539August 15, 2024May 31, 2029MICHAILIDIS, ELEFTHERIOSreporter.nih.gov
4/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)NIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,116,244August 1, 2023July 31, 2030GHOBRIAL, RAFIK MARKreporter.nih.gov
Harnessing big data to arrest the HIV/HCV/opioid syndemic in the rural and urban SouthNIHNational Institute on Drug Abuse2023 to 2025$1,115,625June 1, 2023March 31, 2028REBEIRO, PETER Freporter.nih.gov
How does a metallofactor in Hepatitis B viral protein X orchestrate pathogenesis and liver cancerNIHNational Institute of General Medical Sciences2021 to 2023$1,115,277July 5, 2019June 30, 2024PANDELIA, MARIA-EIRINIreporter.nih.gov
Innate Immunity, Cholesterol, and NASH PathogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,113,750January 20, 2020June 30, 2025GOLDEN, LUCY MARYreporter.nih.gov
Impact of preanalytic procurement and processing variables on the detection of HCC DNA in urineNIHNational Cancer Institute2023 to 2025$1,112,955February 1, 2023January 31, 2028SU, YING-HSIUreporter.nih.gov
Non-invasive screening of diabetics for advanced fibrosis due to NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,109,857May 20, 2020April 30, 2025LOOMBA, ROHITreporter.nih.gov
The role of neutralizing antibodies in natural and treatment-induced control of hepatitis B with and without HIV-1 co-infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,101,905January 24, 2023December 31, 2027BAILEY, JUSTIN RICHARDreporter.nih.gov
Role of Sensory Innervation in High Fat Diet-Induced HepatotoxicityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$1,100,189April 1, 2022April 25, 2024ALPINI, GIANFRANCO Dreporter.nih.gov
Roles for microRNA-122 and circular RNAs in flavivirus RNA amplificationNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,099,000February 15, 2006April 30, 2025SARNOW, PETERreporter.nih.gov
Aryl hydrocarbon receptor-mediated differential gene regulation - Mechanism of stanniocalcin 2 mediated protection against NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,098,375July 12, 2019February 28, 2025JOSHI, ADITYA Dreporter.nih.gov
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingNIHNational Institute on Alcohol Abuse and Alcoholism2021$1,088,145September 30, 2007August 31, 2023PFEFFERBAUM, ADOLFreporter.nih.gov
The Role of p53-R249S’s GOF in HCC developmentNIHNational Cancer Institute2021 to 2023$1,072,557January 1, 2019December 31, 2024LU, HUAreporter.nih.gov
The Determining Effective Testing in Emergency Departments and Care Coordination on Treatment Outcomes (DETECT) for HCV TrialNIHNational Institute on Drug Abuse2021 to 2022$1,050,850March 1, 2018December 31, 2024HAUKOOS, JASONreporter.nih.gov
Nuclear envelope and predisposition to hepatic neoplasiaNIHNational Cancer Institute2023 to 2025$1,049,504August 1, 2023July 31, 2028SHIN, JI-YEONreporter.nih.gov
Nuclear Envelope, Lipoprotein Metabolism, and Hepatic SteatosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,048,784April 10, 2019March 31, 2024WORMAN, HOWARD Jreporter.nih.gov
Organoid-guided Precision Hepatology for SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,046,027February 15, 2024December 31, 2028TAKEBE, TAKANORIreporter.nih.gov
Defining Phenotypes of Alcohol-Associated Liver Disease with Acute Hepatic DecompensationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,043,280June 10, 2021May 31, 2026KWONG, ALLISONreporter.nih.gov
The mitochondrial aspects of health disparity of hepatocellular carcinoma in Hispanic populationNIHNational Cancer Institute2023 to 2025$1,040,371July 1, 2023June 30, 2026BAI, YIDONGreporter.nih.gov
DAMPs and Their Receptors Link Hepatocyte Death to HSC Activation and Liver FibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,039,942September 20, 2019July 31, 2023SCHWABE, ROBERT F.reporter.nih.gov
Individual, Network and Spatial Drivers of HIV and HCV among PWID in IndiaNIHNational Institute on Drug Abuse2021$1,035,149September 1, 2016May 31, 2023SOLOMON, SUNIL SUHASreporter.nih.gov
Deciphering the role of TREM2 in Non-Alcoholic SteatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,031,888April 1, 2023January 31, 2028LIANG, SHUANGreporter.nih.gov
Regulation and Function of Thioredoxin Interacting Protein (Txnip) in Nonalcoholic Steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,026,745July 1, 2023April 30, 2028YANG, LINGreporter.nih.gov
An innovative, non-thiazolidinedione pan-PPAR agonist therapeutic for alcoholic hepatitis: IND-enabling safety and toxicological evaluationNIHNational Institute on Alcohol Abuse and Alcoholism2025$1,025,643May 15, 2022April 30, 2027MANCHEM, PRASADreporter.nih.gov
Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,014,677May 20, 2002June 30, 2027SANYAL, ARUN Jreporter.nih.gov
Epigenetic Heterogeneity as a Driver of Liver Disease and CancerNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$1,012,300August 15, 2018May 31, 2024ROBERTSON, KEITH Dreporter.nih.gov
Targeting Uric Acid as a Therapeutic for NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,010,541May 1, 2020February 28, 2025KHOO, NICHOLASreporter.nih.gov
NAFLD Diagnosis and OutcomesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,007,669February 15, 2024December 31, 2028ALLEN, ALINA Mreporter.nih.gov
Implementing a Community-Based Response to the Opioid Epidemic in Rural Ohio - SupplementNIHNational Institute on Drug Abuse2021 to 2022$1,004,587August 15, 2017July 31, 2023MILLER, WILLIAM Creporter.nih.gov
Genetic and Environmental risk of NAFLD-related HCC In All Latinos: the GENIAL StudyNIHNational Cancer Institute2023 to 2025$1,000,316September 21, 2023August 31, 2027JONES, PATRICIA DENISEreporter.nih.gov
Hepatoselective Dihydrozuinolizone (HS-DHQ) Molecules for Treatment and Prevention of Hepatitis A Virus (HAV) InfectionNIHNational Institute of Allergy and Infectious Diseases2025$1,000,000April 10, 2023July 31, 2027DU, YANMINGreporter.nih.gov
Hepatic FOXA3 Links NAFLD to AtherosclerosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$996,287April 1, 2019March 31, 2025ZHANG, YANQIAOreporter.nih.gov
Advancing a novel potent double anti-HCV nucleoside analog combination treatment for the OUD population to the clinicNIHNational Institute on Drug Abuse2021$995,102September 15, 2019August 31, 2023KLUMPP, KLAUSreporter.nih.gov
Novel insulin-sensitizing NASH/diabetes drugs.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$995,052September 17, 2019August 31, 2023PETERSON, TIMOTHY Rreporter.nih.gov
Novel Paxillin-FAK Inhibitors for the Treatment of Liver FibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$989,753September 15, 2024August 31, 2028MARLOWE, TIMOTHY Areporter.nih.gov
A preclinical multi-modal system for dynamic noninvasive assessment of liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$989,080September 20, 2016February 29, 2024CZERNUSZEWICZ, TOMASZ JOSEPHreporter.nih.gov
Development of a Novel MRI Contrast Agent for Early Detection of Alcoholic SteatohepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021$984,309September 20, 2020February 28, 2023YANG, JENNY J.reporter.nih.gov
Ubiquitin D as a potential therapeutic target for NASH, HCC and chronic kidney diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$980,000August 1, 2023May 31, 2028DHAR, DEBANJANreporter.nih.gov
(PQ6)Nuclear receptor mechanisms in circadian disruption induced hepatocarcinogenesisNIHNational Cancer Institute2021 to 2022$967,903September 18, 2018August 31, 2024FU, LONING NONEreporter.nih.gov
qHTS of Patient Derived HCC Models to Identify Novel Probes/Therapeutic AgentsNIHNational Cancer Institute2021 to 2022$964,654March 1, 2019August 31, 2023JOHNSTON, PAUL A.reporter.nih.gov
Host response and liver disease in a hepatitis C-like virus rat modelNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$964,504February 1, 2018January 31, 2024KAPOOR, AMITreporter.nih.gov
Early detection of HCC using noninvasive activity-based nanosensorsNIHNational Cancer Institute2021$964,382June 1, 2019July 31, 2023WINCKLER, WENDYreporter.nih.gov
Accurate Point of Care Liver Disease Diagnostics, Phase IINIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$947,354September 30, 2022June 30, 2027PRADO, PABLO Jreporter.nih.gov
Vertical Sleeve Gastrectomy for Treatment of NASH: a pilot randomized controlNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$946,907July 14, 2021May 31, 2025IKRAMUDDIN, SAYEEDreporter.nih.gov
Community-based, client-centered prevention homes to address the rural opioid epidemicNIHNational Institute on Drug Abuse2021 to 2022$941,278August 15, 2017July 31, 2023WESTERGAARD, RYAN PATRICKreporter.nih.gov
Resolution of nonalcoholic fatty liver and nonalcoholic steatohepatitis by a novel adipokineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$938,470September 1, 2024June 30, 2026WANG, YONG-XUreporter.nih.gov
California Hub for HIV/STI/SUD Prevention Research with Reentry PopulationsNIHNational Institute on Drug Abuse2025$932,421May 15, 2024July 31, 2029HARAWA, NINA THAWATAreporter.nih.gov
Innate Immunity in NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$929,006July 1, 2023April 30, 2027BAI, JULIreporter.nih.gov
Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$919,166June 15, 2002June 30, 2027TERRAULT, NORAH A.reporter.nih.gov
The Role of HBeAg in HBV PersistenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$907,565August 10, 2018June 30, 2030GUO, HAITAOreporter.nih.gov
C-Type Lectins and Immune Surveillance in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2024$892,164September 1, 2022August 31, 2025KIM, ADAMreporter.nih.gov
Rapid point of care Hepatitis C virus detection using a long-lasting luminescent cascade signal amplificationNIHNational Institute of Allergy and Infectious Diseases2025$884,453November 22, 2024October 31, 2029SHAFIEE, HADIreporter.nih.gov
Novel Hepatitis B Vaccine and ImmunotherapyNIHNational Institute of Allergy and Infectious Diseases2024$883,119August 21, 2024July 31, 2025LAW, MANSUNreporter.nih.gov
Specific-sized hyaluronan: a dual targeted therapy for ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$880,703August 1, 2018July 31, 2025NAGY, LAURA E.reporter.nih.gov
Nutrient Overload, Insulin Resistance, and Hepatic Mitochondrial DysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$878,892July 1, 2017April 30, 2023PARKS, ELIZABETH JANEreporter.nih.gov
Extracellular Vesicles in Alcoholic Liver Disease: Basic and Pre-Clinical DiscoveryNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$868,947July 1, 2020December 31, 2024SZABO, GYONGYIreporter.nih.gov
Mechanisms of parvovirus replication in viral hepatitisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$868,900August 12, 2022July 31, 2027JAGER, MASON CAMERONreporter.nih.gov
HBV cccDNA and integrated DNA in HIV coinfection and HBV monoinfectionNIHNational Institute of Allergy and Infectious Diseases2023$847,428August 3, 2023July 31, 2025LAU, DARYL Treporter.nih.gov
The Landscape of Serious Infections following Kidney Transplantation in People Living with HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$846,608August 19, 2021July 31, 2026WERBEL, WILLIAMreporter.nih.gov
Role of TLR7 in progression and treatment of alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$846,006September 1, 2018December 31, 2024SEKI, EKIHIROreporter.nih.gov
Antiviral prophylaxis and infant vaccination to prevent perinatal hepatitis B infectionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$842,795February 15, 2018January 31, 2025JOURDAIN, GONZAGUE JOSEPHreporter.nih.gov
The role of NLRP6 and DHX15 in control of infection by RNA virusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$837,500January 1, 2018December 31, 2023FIKRIG, EROLreporter.nih.gov
Ataxia Telangiectasia Mutated (ATM)-mediated hepatic DNA damage in pediatric nonalcoholic fatty liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$837,420September 1, 2021July 31, 2026VISWANATHAN, PREETIreporter.nih.gov
Neutrophil elastase in obesity-related fatty liver diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$831,723September 15, 2020August 31, 2025JIANG, ZHEN YUEreporter.nih.gov
Novel hyperpolarized 13C molecular imaging techniques for differentiating NAFLD and NASHNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$831,004September 20, 2018August 31, 2025OHLIGER, MICHAELreporter.nih.gov
Fat and Iron-Corrected Quantitative MRI T1 Mapping for Evaluation of Chronic Liver DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$830,401September 15, 2025July 31, 2030FENG, LIreporter.nih.gov
Role of cholecystokinin receptor in hepatocellular cancerNIHNational Cancer Institute2021 to 2025$814,845September 1, 2021August 31, 2026GAY, MARTHAreporter.nih.gov
Immune analysis of the HBsAg seroclearance response terminating chronic HBVNIHNational Institute of Allergy and Infectious Diseases2025$814,790November 20, 2024October 31, 2029BARON, JODY Lreporter.nih.gov
California Hub for HIV/STI/SUD Prevention Research with Reentry PopulationsNIHNational Institute on Drug Abuse2024$814,282May 15, 2024April 30, 2026HARAWA, NINA THAWATAreporter.nih.gov
The Unfolded Protein Response in Fatty LiverNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$810,996July 1, 2019March 31, 2024GREEN, RICHARD Mreporter.nih.gov
Mechanisms of HBV cccDNA transcriptional regulation in persons with and without HIVNIHNational Institute of Allergy and Infectious Diseases2023$810,981August 14, 2018July 31, 2025BALAGOPAL, ASHWINreporter.nih.gov
Spatial omics to understanding HBV control in people with HIV coinfectionNIHNational Institute of Allergy and Infectious Diseases2025$806,208September 4, 2025August 31, 2030SCHWARTZ, ROBERT Ereporter.nih.gov
Characterizing Hepatitis B Transmission in Congolese ChildrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$803,494June 23, 2020May 31, 2026THOMPSON, PEYTON Jreporter.nih.gov
Establishing the mechanism of benefit and dose of exercise required to improve liver histology in patients with nonalcoholic steatohepatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$800,540February 1, 2022June 27, 2025STINE, JONATHAN Greporter.nih.gov
DAT 18-06 Feasibility and Acceptability of HIV, HCV, and Opioid Use Disorder Services in Syringe Service ProgramsNIHNational Institute on Drug Abuse2021$800,234September 1, 2009July 31, 2022SCHACKMAN, BRUCE Rreporter.nih.gov
Proteogenomics-driven therapeutic discovery in hepatocellular carcinomaNIHNational Cancer Institute2021 to 2024$797,641April 1, 2020March 31, 2026ZHANG, BINGreporter.nih.gov
HCV Ghost Sequencing CenterNIHNational Institute on Drug Abuse2021 to 2022$795,218August 15, 2017July 31, 2023ALLEN, TODD Mreporter.nih.gov
Mechanisms of gut microbiota/metabolite interface-mediated hepatic inflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$794,466August 15, 2022April 18, 2024LI, GUANGFUreporter.nih.gov
Helicobacter Infection and Liver Cancer Risk among African Americans and Whites in the United StatesNIHNational Cancer Institute2024 to 2025$793,720July 16, 2021August 31, 2026ZHANG, XUEHONGreporter.nih.gov
Candidate Selection for Liver Transplantation in Patients with Alcohol-related Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$792,720July 1, 2020June 30, 2026CHEN, PO-HUNG (VICTOR)reporter.nih.gov
A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver diseaseNIHNational Center for Advancing Translational Sciences2021$791,956July 15, 2020June 30, 2022TAYLOR, D. LANSINGreporter.nih.gov
A gerbil model to delineate the mechanism of hepatitis E virus extrahepatic pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$788,000November 9, 2023October 31, 2028MENG, XIANG-JINreporter.nih.gov
Structural Basis for Antiviral Drug Mitochondrial ToxicityNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$782,460March 1, 2018February 28, 2025YIN, YUHUIreporter.nih.gov
Point-of-care magnetofluidic HCV diagnostic using thermally responsive valvesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$781,351March 1, 2024January 31, 2028WHITE, IAN Mreporter.nih.gov
Characterization of silently HBV-infected hepatocytes in HIV co-infectionNIHNational Institute of Allergy and Infectious Diseases2021$779,416August 14, 2018July 31, 2023BALAGOPAL, ASHWINreporter.nih.gov
Myeloid FoxO1 in Lipid MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$778,948August 1, 2019July 31, 2024DONG, HENGJIANG HENRYreporter.nih.gov
Adaptive Liver Tolerance via LSECsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$777,500September 19, 2018August 31, 2023CRISPE, IAN NICHOLASreporter.nih.gov
A Hybrid Implementation-Effectiveness Study of the Pharmacist, Physician, and Patient Navigator Collaborative Care Model to cure Hepatitis C among persons who use drugs with housing insecurityNIHNational Institute on Drug Abuse2025$777,497August 15, 2025April 30, 2030TSUI, JUDITHreporter.nih.gov
Human factors-designed triple test for HIV, HBV, and HCV infection in whole blood using target amplification, signal amplification, and crumpled graphene biosensor readoutNIHNational Institute of Allergy and Infectious Diseases2025$776,341September 16, 2025August 31, 2030CUNNINGHAM, BRIAN T.reporter.nih.gov
Mechanisms of mitochondrial dynamics, quality control and mtDNA-mediated inflammation in alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2024 to 2025$772,738August 20, 2024May 31, 2029DING, WEN-XINGreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of California Los AngelesLos Angeles, CA14$568.6 million0$0
Johns Hopkins UniversityBaltimore, MD42$114.7 million0$0
University of California, San DiegoLa Jolla, CA28$60.3 million0$0
Massachusetts General HospitalBoston, MA25$49.5 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA23$45 million0$0
Yale UniversityNew Haven, CT24$38.5 million0$0
Indiana University IndianapolisIndianapolis, IN18$31.1 million0$0
Duke UniversityDurham, NC9$30.6 million0$0
Brigham and Women's HospitalBoston, MA7$30.6 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC10$30.1 million0$0
University of PennsylvaniaPhiladelphia, PA15$21.8 million0$0
University of Southern CaliforniaLos Angeles, CA22$21.7 million0$0
University of LouisvilleLouisville, KY15$20.7 million0$0
Mayo Clinic RochesterRochester, MN18$20 million0$0
Columbia University Health SciencesNew York, NY15$19.6 million0$0
University of California, San FranciscoSan Francisco, CA19$17.9 million0$0
University of Texas HLTH Science CenterSan Antonio, TX5$17.9 million0$0
Universitat BernBern1$16.8 million0$0
Vanderbilt University Medical CenterNashville, TN4$16.8 million0$0
Stanford UniversityStanford, CA14$16.6 million0$0
Weill Medical Coll of Cornell UnivNew York, NY9$15.5 million0$0
Oklahoma Medical Research FoundationOklahoma City, OK1$15.2 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH11$14.7 million0$0
Research Inst Nationwide Children's HospColumbus, OH13$14.5 million0$0
University of Michigan at Ann ArborAnn Arbor, MI12$13.8 million0$0
Emory UniversityAtlanta, GA16$12.5 million0$0
University of Alabama at BirminghamBirmingham, AL7$12.4 million0$0
North Carolina State UniversityRaleigh, NC2$12.3 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA9$11.8 million0$0
Rockefeller UniversityNew York, NY7$11.8 million0$0
University of KentuckyLexington, KY5$11.7 million0$0
University of WashingtonSeattle, WA10$11.5 million0$0
University of Illinois at ChicagoChicago, IL11$11.3 million0$0
Oregon Health & Science UniversityPortland, OR5$10.9 million0$0
Loyola University ChicagoMaywood, IL6$10.9 million0$0
Scripps Research Institute, theLa Jolla, CA7$10.8 million0$0
Beth Israel Deaconess Medical CenterBoston, MA13$10.8 million0$0
American Type Culture CollectionManassas, VA1$10.7 million0$0
Saint Louis UniversitySaint Louis, MO8$10.7 million0$0
University of Miami School of MedicineCoral Gables, FL7$10.4 million0$0
Wake Forest University Health SciencesWinston-Salem, NC7$10.2 million0$0
Virginia Commonwealth UniversityRichmond, VA9$10.2 million0$0
Chiang Mai UniversityChiang Mai1$10.1 million0$0
Albert Einstein College of MedicineBronx, NY7$9.9 million0$0
University of Missouri-ColumbiaColumbia, MO4$9.5 million0$0
University of Kansas Medical CenterKansas City, KS11$9.1 million0$0
Boston Children's HospitalBoston, MA4$9.1 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY9$9 million0$0
University of MinnesotaMinneapolis, MN7$8.5 million0$0
University of Maryland, College ParkCollege Park, MD5$8.3 million0$0
Fundacao Oswaldo CruzRio de Janeiro1$8.2 million0$0
University of ChicagoChicago, IL5$7.9 million0$0
Baylor College of MedicineHouston, TX8$7.9 million0$0
Ut Southwestern Medical CenterDallas, TX6$7.7 million0$0
University of Texas Med BR GalvestonGalveston, TX6$7.5 million0$0
Princeton UniversityPrinceton, NJ4$7.3 million0$0
University of FloridaGainesville, FL8$7.2 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA6$7.1 million0$0
New York University School of MedicineNew York, NY5$6.8 million0$0
Georgia State UniversityAtlanta, GA3$6.3 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA4$6.2 million0$0
Northwestern University at ChicagoChicago, IL2$6.1 million0$0
Georgetown UniversityWashington, DC7$5.8 million0$0
Fred Hutchinson Cancer CenterSeattle, WA3$5.8 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK5$5.7 million0$0
University of Nebraska Medical CenterOmaha, NE5$5.5 million0$0
Triad National Security, LLCLos Alamos, NM2$5.5 million0$0
University of UtahSalt Lake City, UT4$5.2 million0$0
Ohio State UniversityColumbus, OH7$5.1 million0$0
University of ArizonaTucson, AZ4$4.8 million0$0
Seattle Children's HospitalSeattle, WA2$4.8 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ6$4.6 million0$0
Northern California Institute/res/eduSan Francisco, CA1$4.6 million0$0
Imcare Biotech, Inc.Doylestown, PA3$4.5 million0$0
Tulane University of LouisianaNew Orleans, LA5$4.5 million0$0
University of HawaiiHonolulu, HI2$4.5 million0$0
University of Maryland BaltimoreBaltimore, MD5$4.4 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA4$4.3 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA2$4.2 million0$0
University of VirginiaCharlottesville, VA2$3.8 million0$0
Ohio UniversityAthens, OH3$3.8 million0$0
Starks Associates, Inc.Buffalo, NY1$3.7 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH2$3.7 million0$0
California Pacific Med CTR Res InstituteSan Francisco, CA1$3.6 million0$0
Northeast Ohio Medical UniversityRootstown, OH5$3.5 million0$0
Venatorx Pharmaceuticals, Inc.Malvern, PA2$3.5 million0$0
New York UniversityNew York, NY1$3.4 million0$0
University of Texas at AustinAustin, TX2$3.3 million0$0
Michigan State UniversityEast Lansing, MI2$3.3 million0$0
Louisiana State Univ HSC ShreveportShreveport, LA4$3.2 million0$0
Feinstein Institute for Medical ResearchManhasset, NY2$3.2 million0$0
Translational Genomics Research InstPhoenix, AZ1$3.2 million0$0
Boston University Medical CampusBoston, MA2$3.1 million0$0
Carogen CorporationHamden, CT1$3 million0$0
Gryphon Scientific, LLCTakoma Park, MD1$3 million0$0
Washington UniversitySaint Louis, MO4$3 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA1$2.9 million0$0
University of Wisconsin-MadisonMadison, WI4$2.9 million0$0
Indiana UniversityBloomington, IN3$2.8 million0$0
HbvtechGermantown, MD5$2.7 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025421$338,213,8640$0
2024465$319,037,4230$0
2023472$397,009,1960$0
2022494$436,628,5780$0
2021521$432,401,5990$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 8 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)RFA-DK-27-125NIH93.847November 6, 2026Not listedSame assistance listing 93.847 as 272 awards here
Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)RFA-DK-27-112NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 272 awards here
Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)RFA-DK-27-139NIH93.847November 9, 2026Not listedSame assistance listing 93.847 as 272 awards here
Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)RFA-DK-27-122NIH93.847November 17, 2026Not listedSame assistance listing 93.847 as 272 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.847December 4, 2026Not listedSame assistance listing 93.847 as 272 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.847January 5, 2027Not listedSame assistance listing 93.847 as 272 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.847January 7, 2027Not listedSame assistance listing 93.847 as 272 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.847January 15, 2027$350,000Same assistance listing 93.847 as 272 awards here
Diabetes Research Centers (P30 Clinical Trial Optional)RFA-DK-26-310NIH93.847January 27, 2027$1 millionSame assistance listing 93.847 as 272 awards here
NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)RFA-DK-28-114NIH93.847January 28, 2027Not listedSame assistance listing 93.847 as 272 awards here
KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)RFA-DK-28-312NIH93.847January 30, 2027Not listedSame assistance listing 93.847 as 272 awards here
KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)RFA-DK-28-313NIH93.847January 30, 2027Not listedSame assistance listing 93.847 as 272 awards here
Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)RFA-DK-27-119NIH93.847February 10, 2027$750,000Same assistance listing 93.847 as 272 awards here
Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)RFA-DK-28-116NIH93.847February 10, 2027Not listedSame assistance listing 93.847 as 272 awards here
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)RFA-DK-27-108NIH93.847March 10, 2027$500,000Same assistance listing 93.847 as 272 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.