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Data / Research funding / Heart Disease - Coronary Heart Disease

Heart Disease - Coronary Heart Disease: 1,398 NIH awards ($1.8B) to 275 organizations

1,398 NIH awards ($1.8B) in the NIH spending category Heart Disease - Coronary Heart Disease, to 275 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 1,398 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
JACKSON HEART STUDY (JHS) FIELD CENTER (FC) - TASK AREA DNIHNational Heart, Lung, and Blood Institute2021 to 2023$14,739,138August 13, 2023August 12, 2025CARSON, APRILreporter.nih.gov
1/2 REPRIEVE Extension for Trial CompletionNIHNational Heart, Lung, and Blood Institute2023 to 2025$14,219,228May 1, 2023April 30, 2027GRINSPOON, STEVEN K.reporter.nih.gov
JACKSON HEART STUDY (JHS) COORDINATING CENTER (CC) - TASK AREA DNIHNational Heart, Lung, and Blood Institute2021 to 2024$13,919,988August 13, 2023August 12, 2025CARSON, APRILreporter.nih.gov
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - COORDINATING CENTER - TASK AREA B.2 AND B.3NIHNational Heart, Lung, and Blood Institute2022 to 2025$13,712,636November 15, 2024September 30, 2025COUPER, DAVIDreporter.nih.gov
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchNIHNational Heart, Lung, and Blood Institute2021 to 2025$12,991,264February 8, 2019January 31, 2027CHAVARRO, JORGE EDUARDOreporter.nih.gov
Testing Hypothesized Pathways Linking Infection, Physical Activity, Apoe Genotype, And Biological Sex To Low Dementia Prevalence And Reduced Brain Atrophy In Two Native American PopulationsNIHNational Institute on Aging2022 to 2025$12,690,286April 15, 2017April 30, 2027KAPLAN, HILLARD Sreporter.nih.gov
The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial EXTENDed Follow-up (EXTEND)NIHNational Heart, Lung, and Blood Institute2021 to 2025$10,079,314April 1, 2021March 31, 2027HOCHMAN, JUDITH Sreporter.nih.gov
Immune Cell Interactions in AtherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$9,386,571August 1, 2017May 31, 2027HEDRICK, CATHERINE Creporter.nih.gov
Coronary Artery Calcium and its Association with Protective/Risk Factors and Epigenetic Patterns in Diverse US Hispanic/Latino AdultsNIHNational Heart, Lung, and Blood Institute2021 to 2024$8,752,600June 1, 2021May 31, 2026DAVIGLUS, MARTHA Lreporter.nih.gov
Comprehensive characterization of variants underlying heart and blood diseases with CRISPR base editingNIHNational Human Genome Research Institute2021 to 2025$8,671,281September 1, 2021May 31, 2027PINELLO, LUCAreporter.nih.gov
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)NIHNational Heart, Lung, and Blood Institute2022 to 2025$8,345,645September 10, 2022July 31, 2027SAFFORD, MONIKA Mreporter.nih.gov
Coronary Artery Calcium in the PRagmatic EValuation of evENTs And Benefits of Lipid lowering in the Elderly: CAC PREVENTABLE Ancillary StudyNIHNational Heart, Lung, and Blood Institute2021 to 2025$7,505,536September 1, 2021July 31, 2027DAUBERT, MELISSAreporter.nih.gov
Exosomes as mediators of cardiac injury and repairNIHNational Heart, Lung, and Blood Institute2021 to 2025$7,022,243September 1, 2017June 30, 2029KISHORE, RAJreporter.nih.gov
Objective Physical Activity and Cardiovascular Health in Older Women: OPACH2NIHNational Heart, Lung, and Blood Institute2022 to 2025$6,198,164August 15, 2022June 30, 2027LACROIX, ANDREA Z.reporter.nih.gov
Effects of HIV, Cocaine, and Prolonged ART Use on Subclinical Cardiovascular DiseaseNIHNational Institute on Drug Abuse2021 to 2024$5,744,264June 1, 2016April 30, 2025LAI, SHENGHANreporter.nih.gov
Trial to Assess Chelation Therapy 2 (TACT2) DCC Competing RenewalNIHNational Center for Complementary & Integrative Health2022 to 2024$5,394,975September 30, 2015July 31, 2025MARK, DANIEL Breporter.nih.gov
JACKSON HEART STUDY (JHS) UNDERGRADUATE TRAINING AND EDUCATION CENTER (UTEC) - TASK AREA BNIHNational Heart, Lung, and Blood Institute2021 to 2023$5,146,731August 13, 2023August 12, 2025WHITE, WENDYreporter.nih.gov
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER, TASK AREA BNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,086,390November 15, 2021March 14, 2026LUTSEY, PAMELA L.reporter.nih.gov
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER, TASK AREA BNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,994,412November 15, 2021February 19, 2026WAGENKNECHT, LYNNE Ereporter.nih.gov
IgE antibody responses to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal) in murine and human atherosclerosisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,866,733July 1, 2022June 30, 2027ERICKSON, LOREN Dreporter.nih.gov
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER, TASK AREA BNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,813,353January 15, 2025January 14, 2026WINDHAM, BEVERLY GWENreporter.nih.gov
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTERNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,714,816January 1, 2025December 31, 2025ARGANI, PEDRAMreporter.nih.gov
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - TASK AREA BNIHNational Heart, Lung, and Blood Institute2021 to 2023$4,701,181August 13, 2023August 12, 2025PAYTON, MARINELLEreporter.nih.gov
Multi-functional anti-thrombotic therapy for coronary microvascular obstructionNIHNational Heart, Lung, and Blood Institute2023 to 2025$4,660,810May 1, 2023April 30, 2027CHEN, RIDONGreporter.nih.gov
Altering Cardiac Cell Fate for Heart RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,621,749January 13, 2021November 30, 2027QIAN, LIreporter.nih.gov
IgE antibodies to the mammalian oligosaccharide galactose-alpha-1, 3-galactose (alpha-gal): immunology, epidemiology and relevance to allergic and inflammatory diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,621,686July 1, 1984May 31, 2028PLATTS-MILLS, THOMAS A.reporter.nih.gov
PRE-DETERMINE: Advancing Sudden Arrhythmic Death Prediction in Coronary Artery Disease in the Absence of Severe Systolic DysfunctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$4,550,671February 15, 2023January 31, 2027ALBERT, CHRISTINE Mreporter.nih.gov
Contemporary Classification of Myocardial Injury Events in MESA: Defining Distinct Risk Factor Associations with Myocardial Infarction Type 1-5 and Acute Non-Ischemic Myocardial InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,444,163August 20, 2021July 31, 2027DEFILIPPIS, ANDREWreporter.nih.gov
The VITamin D and OmegA-3 TriaL (VITAL): Post-Intervention Follow-UpNIHNational Center for Complementary & Integrative Health2021 to 2025$4,414,294September 29, 2009December 31, 2026MANSON, JOANN ELISABETHreporter.nih.gov
Mechanisms of Platelet Activity in Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,269,155February 15, 2019January 31, 2027BERGER, JEFFREY Sreporter.nih.gov
Cardiorenal Genomics for Risk Prediction in African Descent PopulationsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,261,183September 1, 2021August 31, 2028IRVIN, MARGUERITE Rreporter.nih.gov
Low-Profile 3D-Printed Radiopaque Bioresorbable Vascular ScaffoldsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,062,443January 1, 2019April 30, 2028AMEER, GUILLERMO ANTONIOreporter.nih.gov
Diagnosis, Prevention, And Treatment Of Cardiovascular Diseases With Genome EditingNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,046,250March 20, 2019February 28, 2026MUSUNURU, KIRANreporter.nih.gov
Patient-specific Outcome Prediction from Cardiovascular Multimodality Imaging by Artificial IntelligenceNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,034,369June 1, 2022May 31, 2029SLOMKA, PIOTR Jreporter.nih.gov
Immune checkpoint inhibitors and accelerated coronary atherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,014,114May 1, 2022April 30, 2027NEILAN, TOMAS Greporter.nih.gov
Engineered Stem Cells for Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,984,462February 1, 2018March 31, 2027REGNIER, MICHAELreporter.nih.gov
RSK3 Anchoring Disruptor Therapy for Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2024$3,961,080September 14, 2023July 31, 2025CIVIDINI, FEDERICOreporter.nih.gov
Cardiac lineage determination and nuclear architectureNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,927,168January 1, 2018December 31, 2024EPSTEIN, JONATHAN A.reporter.nih.gov
Imaging organ system interfaces in ischemic heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,920,729February 1, 2018January 31, 2025NAHRENDORF, MATTHIASreporter.nih.gov
Harnessing Artificial Intelligence and Deep Learning to Determine a Coronary Artery Calcium Estimate in Patients with No History of AtheroSclerotic CardioVascular Disease (HIDDEN-ASCVD) StudyNIHNational Heart, Lung, and Blood Institute2025$3,918,561September 27, 2025August 31, 2029AMBROSY, ANDREW PATRICKreporter.nih.gov
1/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosisNIHNational Heart, Lung, and Blood Institute2025$3,886,403July 30, 2025June 30, 2027PAGIDIPATI, NEHA JADEJAreporter.nih.gov
Managing Cardiac Toxicities of Cancer TherapyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,865,725January 1, 2021December 31, 2027SALLOUM, FADI Nreporter.nih.gov
Jackson Heart Study (JHS) Field CenterNIHNational Heart, Lung, and Blood Institute2025$3,819,327September 15, 2025September 14, 2026reporter.nih.gov
Catheter for Complex Percutaneous Coronary InterventionNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,814,040July 20, 2020January 31, 2027FISCHELL, TIM ALEXANDERreporter.nih.gov
Jackson Heart Study (JHS) Coordinating Center: Task Area A - Core Study OperationsNIHNational Heart, Lung, and Blood Institute2025$3,791,131September 15, 2025September 14, 2035reporter.nih.gov
Investigating Mechanisms for Lipid Transport in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,725,279July 1, 2018June 30, 2025YOUNG, STEPHEN G.reporter.nih.gov
JACKSON HEART STUDY (JHS) GRADUATE TRAINING AND EDUCATION CENTER (GTEC) - TASK AREA BNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,682,352August 13, 2023August 12, 2025RENEKER, JENNIFERreporter.nih.gov
Mechanistic registry to study whether infection with Corona Virus Disease 2019 (COVID-19) accelerates atherosclerotic plaque progressionNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,595,504February 1, 2022June 30, 2026SHAW, LESLEE Jreporter.nih.gov
Human iPSC Model to Elucidate Metabolic Interplay in Diabetic CardimyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,569,593April 1, 2019April 30, 2027WU, JOSEPH C.reporter.nih.gov
PP2A Anchoring Disruptor Therapy in Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,544,947September 1, 2021August 31, 2025CIVIDINI, FEDERICOreporter.nih.gov
Ultrasound Targeted Microbubble Cavitation to Treat Coronary Microvascular ObstructionNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,534,234May 17, 2021April 30, 2027PACELLA, JOHN Jreporter.nih.gov
Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in ObesityNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,475,737September 15, 2020August 31, 2025VAIDYA, ANANDreporter.nih.gov
Leveraging zebrafish models to dissect and enhance heart regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,454,465May 15, 2020December 31, 2024POSS, KENNETH Dreporter.nih.gov
L-2-Hydroxyglutarate and Metabolic Remodeling in HypoxiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,437,123December 20, 2020December 31, 2028LOSCALZO, JOSEPHreporter.nih.gov
Enhancing the public health benefits of mammography screening by informing women of both breast cancer and breast arterial calcification results: A randomized trial to promote cardiovascular healthNIHNational Cancer Institute2021 to 2025$3,435,650April 1, 2022March 31, 2027MONTGOMERY, GUY Hreporter.nih.gov
Dual-modality FLIm and PSOCT for intravascular imaging of plaque in patientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,431,403September 10, 2021August 31, 2026MARCU, LAURAreporter.nih.gov
New Approaches to Mitigate Left Ventricular Injury with VA-ECMO in Acute Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,429,326August 1, 2021July 31, 2025KAPUR, NAVIN KUMARreporter.nih.gov
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,417,341January 15, 2022December 31, 2028LAVINE, KORY J.reporter.nih.gov
SBIR TOPIC 112, FAST-TRACK, INTRAMYOCARDIAL SUTURE ANNULOPLASTY SYSTEM ("MIRTH" AND "SCIMITAR" DEVICES)NIHNational Heart, Lung, and Blood Institute2022 to 2023$3,399,623April 1, 2022March 31, 2026RAFIEE, NASSERreporter.nih.gov
Clonal expansion, resistance to efferocytosis and innate immunity in atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,398,319January 15, 2019December 31, 2024LEEPER, NICHOLAS JAMESreporter.nih.gov
Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)NIHNational Heart, Lung, and Blood Institute2021 to 2024$3,332,837April 21, 2020March 31, 2026GAUDINO, MARIO FLreporter.nih.gov
Molecular Regulation of Atherosclerosis Regression - RenewalNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,330,002April 1, 2006February 28, 2026FISHER, EDWARD Areporter.nih.gov
Using genetic variation to study biology of blood lipids & coronary heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,324,792April 1, 2015June 30, 2026PELOSO, GINA MARIEreporter.nih.gov
Assessment of Mast Cell Degranulation in Infarcted Myocardium Using Quantitative Multiparametric MRINIHNational Heart, Lung, and Blood Institute2022 to 2025$3,298,936July 1, 2022June 30, 2027LI, DEBIAOreporter.nih.gov
Young Adult and Midlife Transitions in Physical Activity and Sedentary Behavior with Heart Failure Risk and Progression: Coronary Artery Risk Development in Young Adults (CARDIA)NIHNational Heart, Lung, and Blood Institute2021 to 2023$3,296,238August 1, 2020July 31, 2025GABRIEL, KELLEY PETTEEreporter.nih.gov
JACKSON HEART STUDY (JHS) COMMUNITY ENGAGEMENT CENTER - TASK AREA B: DEMONSTRATION PROJECTSNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,272,668September 25, 2023September 24, 2024SUTTON, VICTOR Dreporter.nih.gov
Vascular Dysfunction in Myocardial Ischemia and Metabolic SyndromeNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,258,608April 1, 2016June 30, 2027SELLKE, FRANK Wreporter.nih.gov
Exercise Intolerance in Non Obstructive Hypertrophic CardiomyopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,213,836May 1, 2022February 28, 2027ABRAHAM, THEODORE Preporter.nih.gov
Myocardial Steatosis in Women with Coronary Microvascular Dysfunction: Defining the Pathway to Heart Failure with Preserved Ejection Fraction (HFpEF)NIHNational Heart, Lung, and Blood Institute2021 to 2025$3,202,489July 1, 2021June 30, 2026WEI, JANETreporter.nih.gov
Early myocardial remodeling and progressive kidney function decline in type 1 diabetesNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,199,007December 24, 2021November 30, 2026DORIA, ALESSANDROreporter.nih.gov
Clonal Hematopoeisis of Indeterminate Potential and Risk of Autopsy-defined Sudden Cardiac DeathNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,193,873December 1, 2021November 30, 2026TSENG, ZIAN Hreporter.nih.gov
Early Developmental Risk for Adult Cardiovascular Disease: High risk Subgroups, Biomarkers, and MechanismsNIHNational Heart, Lung, and Blood Institute2024 to 2025$3,193,149August 1, 2024May 31, 2028BUKA, STEPHEN Lreporter.nih.gov
Characterization of cardiovascular diseases (CVD) in people with long duration Type 1 diabetesNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,160,264December 24, 2021November 30, 2025KING, GEORGE Lreporter.nih.gov
Polygenic Risk of Disease in Populations of Diverse AncestryNIHNational Human Genome Research Institute2021 to 2025$3,159,052September 8, 2021April 30, 2027SCHAID, DANIEL J.reporter.nih.gov
Endothelial Cell to Mesenchymal Cell Transitions Play a Critical Biological Sex- and Aging-Dependent Role in Formation and Maintenance of the Acta2+ Atherosclerotic Lesion Protective Fibrous CapNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,155,829January 1, 2022December 31, 2025OWENS, GARY Kreporter.nih.gov
L-type channel trafficking and modulation in heartNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,142,708August 1, 2014April 30, 2027COLECRAFT, HENRY M.reporter.nih.gov
Molecular control of cardiac regenerative potentialNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,142,578December 1, 2017December 31, 2026HUANG, GUOreporter.nih.gov
Chemokines in healing myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,140,955June 6, 2005May 31, 2028FRANGOGIANNIS, NIKOLAOS Greporter.nih.gov
Mechanisms of atherosclerotic cardiovascular complicationsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,139,538September 1, 2022August 31, 2026GIANNARELLI, CHIARAreporter.nih.gov
The role of signaling adaptor protein epsin in atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,138,613December 15, 2020November 30, 2025CHEN, HONGreporter.nih.gov
High-throughput investigation of human genetic variants affecting cholesterol uptake and effluxNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,136,707July 1, 2022June 30, 2026SHERWOOD, RICHARD Ireporter.nih.gov
Mental Stress Reactivity in Women with Coronary Microvascular DysfunctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,125,714January 1, 2022April 29, 2025MEHTA, PUJA KIRANreporter.nih.gov
Molecular Imaging of Collagen Turnover in CardiomyopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,124,954July 1, 2022June 30, 2027SADEGHI, MEHRAN Mreporter.nih.gov
Push-Button Cardiac MRI for Non-Invasive Quantification of Myocardial Energy Consumption in Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,123,890August 15, 2022June 30, 2027YANG, HSIN-JUNGreporter.nih.gov
Investigation of Sex and Gender Differences in Cardiovascular Risk in Rural CommunitiesNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,116,310March 1, 2023February 29, 2028SHAH, AMIT JASVANTreporter.nih.gov
Cardiovascular risk from comprehensive evaluation of the CT calcium score examNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,104,134March 15, 2023February 28, 2027WILSON, DAVID LYNNreporter.nih.gov
Regulation of Myocardial Phospholipases and Lipases in Diabetic MyocardiumNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,101,106June 1, 2013January 31, 2026GROSS, RICHARD Wreporter.nih.gov
Aspirin-triggered Specialized Pro-resolving Mediators in Increasing Weight and Atherosclerotic Cardiovascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,089,508April 1, 2021March 31, 2027HEFFRON, SEAN PATRICKreporter.nih.gov
Resolution of inflammation in healing myocardial infarctsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,081,125January 15, 2008December 31, 2026FRANGOGIANNIS, NIKOLAOS Greporter.nih.gov
Ferumoxytol-Enhanced Cardiac MRI for Ischemic Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,066,463July 1, 2020June 30, 2026NGUYEN, KIM-LIEN Treporter.nih.gov
Apolipoprotein M: a novel regulator of myocardial AutophagyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,065,388September 1, 2021August 31, 2026JAVAHERI, ALIreporter.nih.gov
Causal variant association mechanisms in TCF21 binding coronary disease lociNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,054,012January 1, 2017November 30, 2028QUERTERMOUS, THOMASreporter.nih.gov
The PREVENTABLE Physical Performance Ancillary StudyNIHNational Institute on Aging2021 to 2024$3,040,350September 30, 2021May 31, 2028HOUSTON, DENISE KATHRYNreporter.nih.gov
The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in AtherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,039,522December 1, 2021November 30, 2026CHEN, HONGreporter.nih.gov
Platelet Integrin AlphaIIbBeta3 Structure, Activation, and Ligand Binding: Fibrinogen, Fibrin, D-dimer, and von Willebrand FactorNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,038,586September 1, 1976May 5, 2026COLLER, BARRYreporter.nih.gov
Targeting Pyruvate Kinase M2: A novel strategy to combat thrombo-inflammationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,020,183April 1, 2018March 31, 2025CHAUHAN, ANIL KUMARreporter.nih.gov
The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heartNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,015,015January 1, 2021December 31, 2025ZHAO, MINGreporter.nih.gov
The Identification and characterization of genetic variants underlying cardiovascular diseasesNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,015,000January 23, 2017December 31, 2023MANI, ARYAreporter.nih.gov
Genome-wide association study of coronary artery disease in individuals of African ancestryNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,009,772August 1, 2021July 31, 2025LU, YINGCHANGreporter.nih.gov
Whole-genome sequencing analysis of coronary atherosclerosis and related traitsNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,003,154March 17, 2020February 28, 2026DE VRIES, PAUL STEFANreporter.nih.gov
Molecular Mechanisms Governing Vascular Cell Function and Phenotype in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,993,449April 1, 2021March 31, 2026CHEN, HONGreporter.nih.gov
Clinical translation of targeted intracoronary imaging for inflammatory activityNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,992,135July 22, 2022June 30, 2027TEARNEY, GUILLERMO Jreporter.nih.gov
Development of an oxygen delivery biotherapeutic for the preservation of myocardial function during pediatric cardiopulmonary bypassNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,986,551August 1, 2017August 31, 2027WINGER, JONATHAN Areporter.nih.gov
Super Resolution Ultrasound Imaging of Vasa Vasorum to Characterize the Progression of Atherosclerotic Plaques and Predict Rupture VulnerabilityNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,981,035February 1, 2022January 31, 2027KIM, KANGreporter.nih.gov
Dietary Etiologies of Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,960,284December 1, 1985May 19, 2025RIMM, ERIC Breporter.nih.gov
Multiparametric MRI for the investigation of coronary microvascular diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,958,179May 12, 2022April 30, 2027EPSTEIN, FREDERICK Hreporter.nih.gov
Whole genome sequences in ethnically diverse individuals to comprehensively characterize the genetic mechanisms of dyslipidemiasNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,945,022May 1, 2019July 31, 2028NATARAJAN, PRADEEPreporter.nih.gov
Personalized Risk Prediction to Reduce Cardiovascular Disease in Childhood Cancer SurvivorsNIHNational Cancer Institute2022 to 2025$2,933,453July 15, 2022April 30, 2027HOWELL, REBECCA MAUREENreporter.nih.gov
Increasing Ischemic Myocardial Tissue Perfusion by Mechanical LV SupportNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,933,083December 15, 2017November 30, 2026ISHIKAWA, KIYOTAKEreporter.nih.gov
Infusible Extracellular Matrix for Treating Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,929,153June 10, 2022May 31, 2027CHRISTMAN, KAREN Lreporter.nih.gov
2/2 REPRIEVE Extension for Trial CompletionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,915,073May 1, 2023April 30, 2027LU, MICHAEL TSE-YINreporter.nih.gov
Role of Metabolic Reprogramming in Formation and Maintenance of the Acta2+ Atherosclerotic Lesion Protective Fibrous CapNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,900,593July 1, 2021June 30, 2025OWENS, GARY Kreporter.nih.gov
Mitochondrial ATP Synthase in Cardiac Biology and DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,896,074June 1, 2022May 31, 2027KITSIS, RICHARD Nreporter.nih.gov
Integrating Artificial Intelligence for Optimal Analysis of CardiacPET/CTNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,885,687September 22, 2022June 30, 2027SLOMKA, PIOTR Jreporter.nih.gov
Cardiovascular Risk Reduction in an Aging HIV-Infected Population: The Impact of HCV Co-InfectionNIHNational Institute on Aging2021 to 2023$2,851,326May 1, 2019January 31, 2025TRIANT, VIRGINIA ATHENAreporter.nih.gov
Fatigue, Anhedonia and Cardiac Prognostic Markers in Depressed Patients with Coronary Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,842,930June 1, 2020May 31, 2025FREEDLAND, KENNETH Ereporter.nih.gov
Determinants and Outcomes of Nicotine Metabolite Ratio in HIV + SmokersNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,835,005February 10, 2020January 31, 2024GROSS, ROBERTreporter.nih.gov
Deciphering the role of a circadian lncRNA in cardiac remodelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,822,221April 1, 2022March 31, 2027ZHANG, LILEIreporter.nih.gov
Personalized Patient data and behavioral nudges to improve adherence to chronic cardiovascular medicationsNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,821,352July 1, 2018June 30, 2025ALLEN, LARRY ALEXANDERreporter.nih.gov
Cell-Type Specific Mechanisms of HIV CardiomyopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,817,007December 6, 2021November 30, 2025CHI, NEIL Creporter.nih.gov
Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,816,253July 1, 2016November 30, 2026ZHANG, JIANYIreporter.nih.gov
Mechanisms of vascular and valvular calcificationNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,799,000January 1, 2018December 31, 2023GIACHELLI, CECILIA Mreporter.nih.gov
AIBP therapyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,790,000February 1, 2017January 31, 2024MILLER, YURYreporter.nih.gov
Precision antiplatelet therapy after percutaneous coronary interventionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,788,098July 15, 2020June 30, 2026CAVALLARI, LARISA HUMMAreporter.nih.gov
Sympathetic remodeling and ventricular arrhythmiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,772,140September 1, 2025June 30, 2029RIPPLINGER, CRYSTAL MAYreporter.nih.gov
Links between Cardiovascular disease, Lung disease, and Obstructive sleep apnea in HIV: Understanding complex patientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,768,708September 12, 2014June 30, 2027CRANE, HEIDI M.reporter.nih.gov
Personalized lesion modification optimizes atherosclerosis interventionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,767,637January 1, 2022December 31, 2025EDELMAN, ELAZER Rreporter.nih.gov
Role of GPNMB in cardiac remodelingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,753,048December 20, 2020November 30, 2025DEB, ARJUNreporter.nih.gov
New Risk Models for Diabetes Complications Using Electronic Health RecordsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,749,048April 1, 2022March 31, 2027NAU, CLAUDIA LEONIEreporter.nih.gov
Long-Acting RNAi Therapy for Atherosclerosis and Insulin ResistanceNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,745,822July 1, 2021June 30, 2026SHI, JINJUNreporter.nih.gov
THE MITOCHONDRIAL DYNAMISM/FITNESS/BIOGENESIS INTERACTOME IN CARDIAC DISEASENIHNational Heart, Lung, and Blood Institute2021 to 2023$2,745,000January 16, 2017December 31, 2023DORN, GERALD W.reporter.nih.gov
Protection of Ischemic MyocardiumNIHNational Heart, Lung, and Blood Institute2021$2,741,275December 1, 2004August 31, 2023BOLLI, ROBERTOreporter.nih.gov
Computational model-driven design to mitigate vein graft failure after coronary artery bypassNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,736,546August 15, 2022June 30, 2027MARSDEN, ALISON Lreporter.nih.gov
Metal Exposure and Early Cardiovascular Risk in Adult E-Cigarette UsersNIHNational Institute of Environmental Health Sciences2021 to 2024$2,730,969August 1, 2020May 31, 2026NAVAS-ACIEN, ANAreporter.nih.gov
Mechanisms of coronary flow heterogeneity: Implications for coronary sinus occlusion therapyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,730,095July 1, 2022June 30, 2026KASSAB, GHASSAN Sreporter.nih.gov
Role of group 2 innate lymphoid cells in myocardial infarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,714,930December 15, 2021November 30, 2026LIBBY, PETERreporter.nih.gov
Free fatty acid receptor 4 cardioprotective effects in cardiac ischemic injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,702,022April 1, 2020March 31, 2026O'CONNELL, TIMOTHY Dreporter.nih.gov
PDGFD regulates a transcriptional network to modulate smooth muscle cell transition and coronary artery disease riskNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,687,815April 15, 2021March 31, 2026QUERTERMOUS, THOMASreporter.nih.gov
Disentangling the Mechanisms of Coronary Blood Flow Regulation through Multi-scale ModelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,686,324March 15, 2022February 28, 2027FIGUEROA, CARLOS ALBERTOreporter.nih.gov
Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large MammalsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,675,195August 9, 2022June 30, 2027ZHU, WUQIANGreporter.nih.gov
Multi-isotope Hybrid PET/CT Imaging of Peripheral Artery Disease in DiabetesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,663,222December 19, 2022November 30, 2025SINUSAS, ALBERT Jreporter.nih.gov
Dissecting the role of CD8+ T cells in atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,662,899August 20, 2020May 31, 2025GIANNARELLI, CHIARAreporter.nih.gov
Identifying tobacco-genetic interactions through study of the aryl hydrocarbon receptor pathway.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,657,964April 1, 2021March 31, 2026QUERTERMOUS, THOMASreporter.nih.gov
Multimodal genetic regulatory architecture of coronary artery diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,653,823June 1, 2019June 30, 2028MILLER, CLINT Lreporter.nih.gov
Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$2,649,589July 1, 2021April 30, 2027LIU, CHUNYUreporter.nih.gov
ShRNA-Based Targeting of mAKAPβ in Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,647,016July 1, 2019April 30, 2024CIVIDINI, FEDERICOreporter.nih.gov
Ventricular arrhythmias and mechanisms of parasympathetic dysfunction following myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,637,195July 1, 2020June 30, 2025VASEGHI, MARMARreporter.nih.gov
Slowing Atherothrombosis Progression through Indoor Air Filtration: A Crossover Trial in Hispanic and non-Hispanic Adults with Ischemic Heart Disease HistoryNIHNational Institute of Environmental Health Sciences2022 to 2024$2,604,505September 1, 2022June 30, 2027CHEN, ZHANGHUAreporter.nih.gov
Gadolinium Free Cardiac MR Imaging of Scar and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,587,786July 1, 2020June 30, 2025NEZAFAT, REZAreporter.nih.gov
Modulation of Mitofusin Activity to Treat Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,574,028August 1, 2021July 31, 2025KITSIS, RICHARD Nreporter.nih.gov
Cell-specific role and therapeutic potential of KCa3.1 in atherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,572,517April 1, 2022March 31, 2027BOWLES, DOUGLAS Kreporter.nih.gov
Improve the Meaning of Patient Reported Outcomes to Evaluate Effectiveness for Cardiac Care" (IMPROVE-Cardiac Care)NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,557,678July 23, 2022June 30, 2027MASTERSON CREBER, RUTH MARIEreporter.nih.gov
Nrf2 regulation of oxidative stress in heart failure and extra vesicular communicationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,552,315April 1, 2021March 31, 2026ZUCKER, IRVING Hreporter.nih.gov
Impact of cardiomyocyte cell cycle activity on atrial structural and functional remodeling following myocardial infarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,552,004April 22, 2022March 31, 2027FIELD, LOREN Jreporter.nih.gov
YAP and IRF2BP2 regulation of cardiomyocyte innate immune responsesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,549,340December 15, 2021November 30, 2026LIN, ZHIQIANGreporter.nih.gov
Effect of Hospital-Cardiologist Integration on Clinical Practice, Healthcare Quality, and Medicare SpendingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,547,645July 1, 2020April 30, 2026MOGHTADERI, ALIreporter.nih.gov
Functional roles of lymphatics in organogenesis and tissue repairNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,543,362January 7, 2021December 31, 2025OLIVER, GUILLERMO Creporter.nih.gov
Genetic interactions and multifactorial genetics mediate myocardial regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,532,602February 11, 2021June 30, 2026PATTERSON, MICHAELAreporter.nih.gov
Cyclic nucleotide phosphodiesterase regulation in vascular calcificationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,529,665June 15, 2022May 31, 2027CAI, YUJUNreporter.nih.gov
Vascular dysfunction in coronary microcirculationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,526,989December 10, 2021November 30, 2026DAS, KUMUDA Creporter.nih.gov
Dual Functionality of Ceramide in Human Microvascular Endothelial FunctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,525,399July 1, 2022June 30, 2027FREED, JULIE Kreporter.nih.gov
CARDIA-PLUS: A Life Course Investigation of Biopsychosocial Pathways to Bladder Health and Lower Urinary Tract SymptomsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,525,060August 15, 2021July 31, 2025BRADY, SONYA Sreporter.nih.gov
Integrating Coronary Atherosclerosis with Physiologic Features for Optimized Risk StratificationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,517,408March 4, 2021February 28, 2026STONE, PETER HOWARDreporter.nih.gov
IGF::OT::IGF ATHEROSCLEROSIS IN RISK COMMUNITIES - COORDINATING CENTER - CORE STUDY OPERATIONSNIHNational Heart, Lung, and Blood Institute2021$2,517,180November 15, 2016November 14, 2021COUPER, DAVIDreporter.nih.gov
CD45-mediated endothelial-to-mesenchymal transition in cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,516,934January 15, 2020December 31, 2025CHEN, HONGreporter.nih.gov
PRIMECare Trial: Preventing Ischemic Heart Disease with mHealth, electronic decision support, and Community Health Workers.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,514,537August 1, 2020May 19, 2025GAZIANO, THOMAS Areporter.nih.gov
Intravascular microstructural, chemical and biomechanical characterization of coronary plaquesNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,503,838August 1, 2022April 30, 2027URIBE-PATARROYO, NESTORreporter.nih.gov
A hypercholesterolemia-induced immunometabolite in atherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,499,404December 1, 2021November 30, 2025SHAH, PREDIMAN KRISHANreporter.nih.gov
Prevention of heart failure with IL-1 blockade: a mechanistic studyNIHNational Institute on Aging2022 to 2025$2,490,717March 1, 2022February 28, 2027VAN TASSELL, BENJAMIN Wreporter.nih.gov
Mechanisms of Gap Junction RegulationNIHNational Institute of General Medical Sciences2021 to 2025$2,488,213June 1, 2006June 30, 2027SORGEN, PAUL Lreporter.nih.gov
Multiparametric PET/MRI Assessment of Mast Cell Stabilization Effects on Inflammaging and Glucose Utilization in Infarcted MyocardiumNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,488,056April 1, 2023March 31, 2027COKIC, IVANreporter.nih.gov
3D Multi-Functional Catheter-Based Imaging of Coronary Lesion Composition, Structure, and Hemodynamics in Intermediate StenosesNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,487,260July 1, 2021March 31, 2026LINDSEY, BROOKS Dreporter.nih.gov
New methods for constructing and evaluating polygenic scoresNIHNational Human Genome Research Institute2021 to 2023$2,484,299September 14, 2020June 30, 2025PRITCHARD, JONATHAN Kreporter.nih.gov
Coronary plaque changes with statin and colchicine among people with high polygenic risk- a mechanistic pilot studyNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,484,226July 1, 2023June 30, 2028FAHED, AKL Creporter.nih.gov
Mechanobiology of Cardiopulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,483,485January 11, 2017December 31, 2023MERRYMAN, WILLIAM Dreporter.nih.gov
Caspase-9 as a nodal point connecting necrotic and apoptotic cell death in myocardial infarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,475,519July 15, 2022June 30, 2027KITSIS, RICHARD Nreporter.nih.gov
Neurotrophins and post-infarct plasticity in cardiac sympathetic neuronsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,471,774July 15, 2009June 30, 2028HABECKER, BETH Areporter.nih.gov
Cell-Selective Therapies for Coronary Artery DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,469,740July 15, 2015December 31, 2026TOTARY-JAIN, HANAreporter.nih.gov
PIK3C3, a master regulator for smooth muscle identityNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,467,369December 1, 2021November 30, 2026ZHOU, JILIANGreporter.nih.gov
Engineered Granular Hydrogels for Endogenous Tissue RepairNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,464,894May 26, 2022April 30, 2027BURDICK, JASON Areporter.nih.gov
Mechanism of transplanted neonatal cardiac progenitor cells to repair ischemic myocardiumNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,462,741April 20, 2014August 31, 2025SCHUMACKER, PAUL Treporter.nih.gov
ETS2-dependent control in cardiomyocyte ischemia/reperfusion injuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,459,070August 1, 2022July 31, 2026HILL, JOSEPH Areporter.nih.gov
Genetic modifiers of atherosclerosis and macrophage phenotypesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,457,383July 1, 2021June 30, 2026SMITH, JONATHAN Dreporter.nih.gov
Disruptions in ST-Elevation Myocardial Infarction Transfer Networks and Cardiovascular Health of Rural AmericansNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,454,092May 15, 2021April 30, 2027NIKPAY, SAYEH SANDERreporter.nih.gov
Sex-Specific Risk of Metabolic and Cardiovascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,450,619June 15, 2019June 30, 2025STAFFORD, JOHN MICHAELreporter.nih.gov
Metabolic mechanisms of cardioprotection through alpha-1A adrenergic receptor activationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,447,412December 15, 2017December 31, 2027JENSEN, BRIAN Creporter.nih.gov
A novel psychological-behavioral intervention to promote physical activity after acute coronary syndromeNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,439,296June 1, 2022June 30, 2027HUFFMAN, JEFF Creporter.nih.gov
Translating post-infarct ventricular tachycardia mechanisms into a therapyNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,437,249January 9, 2023December 31, 2026DONAHUE, J KEVINreporter.nih.gov
Gut microbial metabolites and risk of coronary heart disease: a prospective, multiethnic, metabolomic studyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,429,547July 15, 2020June 30, 2025YU, DANXIAreporter.nih.gov
Dissecting the role of the cardiac fibroblast in hypertrophy.NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,423,816July 18, 2022April 30, 2026MOLKENTIN, JEFFERY Dreporter.nih.gov
miR-181b, endothelial cells, and vascular inflammationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,414,330August 1, 2012July 31, 2026FEINBERG, MARK Wreporter.nih.gov
Genetic circuitry governing heart growth and repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,413,285March 1, 2022February 28, 2027HUANG, GUOreporter.nih.gov
Innate immune response signaling in cardiac injury healingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,408,533January 1, 2022December 31, 2026MOLKENTIN, JEFFERY Dreporter.nih.gov
Development of advanced cardiac SPECT imaging technologiesNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,404,971August 1, 2020June 30, 2025LIU, CHIreporter.nih.gov
Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,403,242April 15, 2019June 30, 2030SUN, QIreporter.nih.gov
Role of IL-6 trans signaling in atherosclerosis development and late-stage pathogenesisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,401,494April 15, 2023March 31, 2027OWENS, GARY Kreporter.nih.gov
Polymorphic ApoE at the crossroad of lipid metabolism and inflammation in atherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,398,270December 1, 2021November 30, 2026HUI, DAVID YIU-KWANreporter.nih.gov
SPHINGOLIPID BIOLOGY OF MACROPHAGE IN CORONARY ATHEROSCLEROSIS DEVELOPMENT AND PROGRESSIONNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,395,181January 1, 2021December 31, 2025DI LORENZO, ANNARITAreporter.nih.gov
Women's Ischemia Syndrome Evaluation (WISE) - Mechanisms of Coronary Microvascular Dysfunction Leading to Pre-Heart Failure with Preserved Ejection Fraction (HFpEF)NIHNational Heart, Lung, and Blood Institute2021 to 2023$2,389,719May 1, 2019February 28, 2026BAIREY MERZ, CATHLEEN NOELreporter.nih.gov
Role of Smooth Muscle Cell Insulin Resistance and Systemic Metabolic Dysfunction in Atherosclerosis Development and Late Stage Lesion PathogenesisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,389,239July 15, 2023June 30, 2027OWENS, GARY Kreporter.nih.gov
Electrocardiographic Detection of Non-ST Elevation Myocardial Events for Accelerated Classification of Chest Pain Encounters (ECG-SMART 2)NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,387,374April 15, 2018June 30, 2026AL-ZAITI, SALAH Sreporter.nih.gov
Endothelial plasticity in cardiac repair after myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,384,851August 11, 2021July 31, 2025FAN, YIreporter.nih.gov
CRISPR-induced cardiovascular progenitor cells to repair myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,382,655April 1, 2021March 31, 2026WANG, YIGANGreporter.nih.gov
Very early drivers of neutrophilic inflammation in cardiac ischemia-reperfusionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,367,912August 1, 2018March 31, 2029LEVIT, REBECCA DIANEreporter.nih.gov
Multi-center, randomized, controlled trial of the feasibility and safety of inhaled hydrogen gas during ECPRNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,366,065September 1, 2022August 31, 2026KHEIR, JOHN NAGIreporter.nih.gov
Mechanotransduction and transcriptional regulation during artery developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,363,601September 1, 2015June 30, 2025RED-HORSE, MARYreporter.nih.gov
Quantitative Detection of Coronary Microvascular Dysfunction in Long COVID Patients using a Comprehensive, Rapid, Free-Breathing Cardiovascular MRINIHNational Heart, Lung, and Blood Institute2023 to 2025$2,361,031April 15, 2023March 31, 2027KIM, DANIELreporter.nih.gov
Molecular mechanisms of vascular calcification and their connection to coronary disease riskNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,360,671August 1, 2022May 31, 2027QUERTERMOUS, THOMASreporter.nih.gov
Blood mitochondrial DNA biomarkers of midlife cognitive decline and adverse brain imaging changes - A longitudinal investigation in the CARDIA population‐based cohort studyNIHNational Institute on Aging2021 to 2023$2,348,964July 15, 2020April 30, 2025BACCARELLI, ANDREAreporter.nih.gov
Methods for Enhancing Polygenic Risk Prediction Models for Complex DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,346,100July 1, 2023April 30, 2027KIM, DOKYOONreporter.nih.gov
Evaluation of artificial intelligence-controlled CPR to improve vital organ perfusion and survival during prolonged resuscitationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,342,113April 15, 2021March 31, 2026YANNOPOULOS, DEMETRISreporter.nih.gov
Myocardial Vulnerability to Ischemia-Induced Dysfunction and Heart Failure: The Impact of HIV/SIV, ART, and Targeted ImmunotherapyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,339,875August 1, 2020June 30, 2025FEINSTEIN, MATTHEW JOELreporter.nih.gov
Cardioprotective role of Humanin in agingNIHNational Institute on Aging2021 to 2025$2,334,715September 30, 2021May 31, 2027MUZUMDAR, RADHIKA HIRENreporter.nih.gov
Efferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic HeartNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,334,070April 1, 2014January 31, 2025THORP, EDWARD BENJAMINreporter.nih.gov
Junctophilin-2 cleavage in ischemic heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,333,916April 1, 2021March 31, 2026WEHRENS, XANDER H.T.reporter.nih.gov
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,333,316September 15, 2016May 31, 2025ZHANG, JIANYIreporter.nih.gov
Integrative genomic and functional genomic studies to connect variant to function for CAD GWAS lociNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,327,515April 1, 2023March 31, 2027ZHANG, HANRUIreporter.nih.gov
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,324,312May 1, 2012July 31, 2025VACCARINO, VIOLAreporter.nih.gov
Targeting LRRC8 signaling to prevent & treat arterial thrombosis in type 2 diabetesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,320,705September 1, 2023August 31, 2026LERNER, DANIEL Jreporter.nih.gov
Optimization of diagnostic accuracy, radiation dose, and patient throughput for cardiac SPECT via advanced and clinically practical cardiac-respiratory motion correction and deep learningNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,320,020July 1, 2020June 30, 2025YANG, YONGYIreporter.nih.gov
Pericoronary fat: MACE risk from non-contrast CT and the role of iodine perfusion in contrast CTNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,315,094February 15, 2023January 31, 2027WILSON, DAVID LYNNreporter.nih.gov
Sociocultural Shifting, Sleep and Cardiometabolic Risk in African-American WomenNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,314,054August 8, 2023July 31, 2028LEWIS, TENÉ Treporter.nih.gov
Engineering a Microphysiological System to Model the Infarct Border Zone and Interrogate Oxygen-Dependent Cell-Cell Communication in the MyocardiumNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,307,632June 15, 2020June 30, 2029MCCAIN, MEGAN LAURAreporter.nih.gov
Mechanisms Underlying Takotsubo SyndromeNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,301,876July 1, 2022December 31, 2026CHILIAN, WILLIAM Mreporter.nih.gov
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,301,317July 5, 2017November 30, 2026MILLER, LAURENCE Jreporter.nih.gov
Functional genomics investigation of pleiotropic vascular disease lociNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,287,605June 15, 2022May 31, 2027MILLER, CLINT Lreporter.nih.gov
Flow regulation of the Alk1/Eng pathway in vascular homeostasis and diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,277,780July 15, 2023May 31, 2027EICHMANN, ANNE CHRISTINEreporter.nih.gov
Elucidation of P2X7 Receptor Signaling and Development of Novel Small Molecule and Aptamer Ligand TherapiesNIHNational Institute of General Medical Sciences2022 to 2025$2,276,100September 1, 2022August 31, 2027MANSOOR, STEVEN ELIASreporter.nih.gov
Integrated prediction of cardiovascular events by automated coronary plaque and pericoronary adipose tissue quantification from CT AngiographyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,275,582May 15, 2020March 31, 2025DEY, DAMINIreporter.nih.gov
Coronary Atherosclerosis and Immune Activation in HIV and Tuberculosis InfectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,274,138August 2, 2022July 31, 2027HUAMAN JOO, MOISES ARTUROreporter.nih.gov
A dual-layer flat panel x-ray detector based on an engineered amorphous chalcogenide alloy for quantifying coronary artery calciumNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,262,800September 7, 2022May 31, 2027ABBASZADEH, SHIVAreporter.nih.gov
Cardiac Magnetic Resonance Tissue Characterization of Ischemic and Non-Ischemic Myocardium to Predict Left Ventricular Functional Recovery and Outcomes after Multivessel Coronary RevascularizationNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,261,618September 1, 2023August 31, 2028GAUDINO, MARIO FLreporter.nih.gov
Heterogeneity and predictors of stress reactivity in takotsubo syndromeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,255,920March 1, 2020February 28, 2026SALMOIRAGO-BLOTCHER, ELENAreporter.nih.gov
Phase resolved ARF optical coherence elastography for intravascular imagingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,255,269August 15, 2014June 30, 2026CHEN, ZHONGPINGreporter.nih.gov
Harnessing Platelet-Endothelial Interactions for Exosome DeliveryNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,253,989April 1, 2019July 31, 2027CHENG, KEreporter.nih.gov
Non-invasive imaging of reactive oxygen species in reperfusion injury myocardial infarctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,248,106July 1, 2023April 30, 2027WITSCHEY, WALTER R.T.reporter.nih.gov
Molecular predictors of cardiovascular events and resilience in chronic coronary artery diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,248,079August 15, 2023May 31, 2028NEWMAN, JONATHAN Dreporter.nih.gov
Leveraging Hispanic/Latino diversity to map and characterize cardiovascular disease lociNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,242,384January 16, 2023December 31, 2026GRAFF, MARIAELISAreporter.nih.gov
Targeting a ectonucleotidase in the heart with a monoclonal antibody to prevent post-infarct heart failureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,239,092August 14, 2023June 30, 2027DEB, ARJUNreporter.nih.gov
Reducing cardiac toxicity with deep learning and MRI-guided radiation therapyNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,238,763August 23, 2021July 31, 2026GLIDE-HURST, CARRI KAYEreporter.nih.gov
Proteomic discovery in an inception cohort of acute myocardial infarction survivorsNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,226,608August 15, 2020July 31, 2025FLOYD, JAMES Sreporter.nih.gov
Scar Detection and Treatment with Droplet ActivationNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,222,376April 1, 2020March 31, 2025PORTER, THOMAS Rreporter.nih.gov
Coronary Artery Calcium, Aortic Calcification and Density in MESANIHNational Heart, Lung, and Blood Institute2021 to 2023$2,221,188April 1, 2020March 31, 2025BUDOFF, MATTHEW Jreporter.nih.gov
Extreme Heat and Acute Myocardial Infarction: Effect Modifications by Sex, Medical History, and Air PollutionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,213,010September 4, 2023June 30, 2028CHEN, KAIreporter.nih.gov
Role of intermittent activation of parathyroid hormone receptor in exercise-induced vascular calcificationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,200,489January 1, 2021December 31, 2025DEMER, LINDA L.reporter.nih.gov
Improving Cardiac Rehabilitation outcomes through mobile case management (iCARE)NIHNational Institute of Nursing Research2021 to 2024$2,199,791September 14, 2020July 31, 2025OLSON, THOMAS PATRICKreporter.nih.gov
The role of MLKL in the regulation of vascular calcification in CKDNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,198,457June 1, 2016May 31, 2027MIYAZAKI, MAKOTOreporter.nih.gov
Strategies to Enhance Engineered Heart Tissue Based Myocardial RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,196,794January 1, 2023November 30, 2026ZHU, WUQIANGreporter.nih.gov
Quantitative coronary flow capacity with low-dose CT for ischemia but no obstructive coronary artery diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,195,209July 1, 2023April 30, 2028MOLLOI, SABEEreporter.nih.gov
Sodium Dependent Inactivation of the Na+-Ca2+ exchange: Relevance to Cardiac FunctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,187,514December 18, 2020November 30, 2025OTTOLIA, MICHELAreporter.nih.gov
Deviceless and Autonomous Prospective Cardiac CT TriggeringNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,187,003August 1, 2020May 30, 2024DE MAN, BRUNOreporter.nih.gov
Role of Cilp1 in Post-Natal Heart Response to InjuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,184,041June 1, 2022May 31, 2027LIU, ZHI-PINGreporter.nih.gov
Mitochondrial metabolism and macrophage function post MINIHNational Heart, Lung, and Blood Institute2021 to 2023$2,177,813July 1, 2020December 31, 2025TIAN, RONGreporter.nih.gov
Coronary Atherosclerotic Burden in AsA-NHPI: the Role of the Gut MicrobiomeNIHNational Heart, Lung, and Blood Institute2025$2,177,784September 12, 2025June 30, 2029AHN, JIYOUNGreporter.nih.gov
Premature aging disorders, metabolites, and atherosclerosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,173,716December 15, 2022November 30, 2026ABE, JUN-ICHIreporter.nih.gov
Mechanistic Studies of the Novel Human Coronary Artery Disease Gene SVEP1NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,173,015April 1, 2022February 28, 2027STITZIEL, NATHAN OLIVERreporter.nih.gov
Understanding the molecular mechanism of cardiomyocyte dedifferentiation and proliferation during regenerationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,169,578January 1, 2022December 31, 2026TSANG, MICHAEL WAIKOKreporter.nih.gov
Protein Kinase Novel 2 (PKN2) in heartNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,167,993January 1, 2021December 31, 2024CHEN, JUreporter.nih.gov
Subendothelial Exosomes in Coronary Microvascular DysfunctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,167,298March 15, 2004March 31, 2026LI, PINLANreporter.nih.gov
Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,160,217April 22, 2020May 31, 2029MOHAMED, TAMER M Areporter.nih.gov
Macrophages in homeostasis and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,158,562June 25, 2021February 28, 2024SWIRSKI, FILIP Kreporter.nih.gov
Extracellular Matrix Dynamics During RemodelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,156,647April 1, 2022March 31, 2027JONES, STEVEN Preporter.nih.gov
Informing best practices for evaluation and treatment of myocardial injury during sepsisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,156,394September 1, 2023June 30, 2027WALKEY, ALLAN J.reporter.nih.gov
Endothelial Regulation of Vascular CalcificationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,152,920January 1, 2022August 31, 2026BOSTROM, KRISTINA Ireporter.nih.gov
Mechanisms of epicardium-directed coronary vessel patterningNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,152,475September 1, 2022August 31, 2026SMALL, ERIC Mreporter.nih.gov
Retinoid Metabolism in the Adult Heart and Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,140,517April 1, 2023March 31, 2027FOSTER, D BRIANreporter.nih.gov
Effects of chronic marijuana use on endothelial functionNIHNational Institute on Drug Abuse2023 to 2025$2,140,358July 1, 2023April 30, 2028SPRINGER, MATTHEW LAWRENCEreporter.nih.gov
Ultrasound-mediated Controlled Hypoxemic Reperfusion for Inhibition of Reperfusion InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,138,796July 1, 2019April 30, 2025HAWORTH, KEVIN JOSEPHreporter.nih.gov
Critical role of Mitochondrial Fission/Fusion in Regulation of Microvascular Endothelial FunctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,127,892August 1, 2021July 31, 2025BEYER, ANDREAS Mreporter.nih.gov
TRP channels in the regulation of vascular toneNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,126,388February 4, 2011June 30, 2026ZHANG, DAVID X.reporter.nih.gov
Role of S-Nitrosylation on Beta-Adrenergic Signaling in Cardiac Injury and RepairNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,120,983April 1, 2021July 31, 2023KOCH, WALTER J.reporter.nih.gov
Mechanisms controlling epicardial-dependent promotion of heart regeneration in zebrafish.NIHNational Heart, Lung, and Blood Institute2021 to 2025$2,118,750July 5, 2021June 30, 2027CAO, JINGLIreporter.nih.gov
Human CDX2 Cells and Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,116,925July 21, 2020May 31, 2025CHAUDHRY, HINA Wreporter.nih.gov
Molecular and Cellular Regulation of Vascular CalcificationNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,114,102January 4, 2024December 31, 2030GIACHELLI, CECILIA Mreporter.nih.gov
Clinical and immunologic factors underlying heart failure with preserved ejection fraction among persons with HIV in South AfricaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,113,979September 15, 2021August 31, 2025BAKER, JASON Vreporter.nih.gov
Genomic and Proteomic Architecture of AtherosclerosisNIHNational Heart, Lung, and Blood Institute2021$2,113,515July 18, 2012January 31, 2024HERRINGTON, DAVID MCLEODreporter.nih.gov
Influence of sleep on the hematopoietic niche and atherosclerosis during agingNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,113,125July 1, 2021May 31, 2026MCALPINE, CAMERON STUARTreporter.nih.gov
Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular HealthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$2,105,761September 1, 2021July 31, 2025SHUFELT, CHRISANDRA LEEreporter.nih.gov
Mechanisms of Cardiac TRPV1 Afferent Remodeling in Ventricular ArrhythmiasNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,101,388September 15, 2021July 31, 2025AJIJOLA, OLUJIMI Areporter.nih.gov
Mediterranean diet, Metabolites, and Cardiovascular DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,096,138July 15, 2013February 28, 2027HU, FRANK Breporter.nih.gov
Proof of concept and dose response of CAM-6019 for HFrEF patientsNIHNational Heart, Lung, and Blood Institute2025$2,095,748October 1, 2025September 30, 2027UMANSKY, KFIRreporter.nih.gov
Calcineurin compartmentation and regulation of pathological cardiac remodelingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,095,434April 1, 2021September 30, 2025KAPILOFF, MICHAEL SETHreporter.nih.gov
Cell Based Immunomodulation to Promote Post-Infarct Myocardial RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,094,218December 10, 2022November 30, 2027GHANTA, RAVI Kreporter.nih.gov
Extracellular miRNAs, innate immunity, and critical illnessNIHNational Institute of General Medical Sciences2021 to 2025$2,091,584May 1, 2021February 28, 2027CHAO, WEIreporter.nih.gov
Trial to Assess Chelation Therapy 2- TACT2 CCCNIHNational Center for Complementary & Integrative Health2021$2,069,251September 30, 2015April 30, 2022LAMAS, GERVASIO Areporter.nih.gov
Sorbs2 targeting and BK channel regulation in the coronary artery of patients with type 1 diabetesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,065,272August 5, 2022January 31, 2027LU, TONGreporter.nih.gov
Skeletal Muscle Nrf2: Exercise-Induced Cardiovascular ProtectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,062,719January 15, 2022December 31, 2026GAO, LIEreporter.nih.gov
Manganese-based Contrast Agent for Cardiovascular MRINIHNational Heart, Lung, and Blood Institute2023 to 2024$2,057,361December 15, 2020May 31, 2026HOFFMAN, VERAreporter.nih.gov
Epigenetic mechanisms linking psychosocial stress with coronary heart diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,054,791April 1, 2022March 31, 2027ZANNAS, ANTHONY S.reporter.nih.gov
Inhibition of Radiation-Induced Coronary Microvascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,050,609January 15, 2021December 31, 2026POKHAREL, SARASWATIreporter.nih.gov
Discovery and therapeutic targeting non-coding RNAs in T1D- or T2D-associated atherosclerosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$2,045,222September 18, 2024June 30, 2027FEINBERG, MARK Wreporter.nih.gov
Validation of Platelet Expression of FcɣRIIa as a Precision ToolNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,045,163August 11, 2022July 31, 2025OHRNBERGER, JEANNEreporter.nih.gov
Insulin-Like Growth Factor-1 and AtherosclerosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,035,860December 5, 2002June 30, 2027DELAFONTAINE, PATRICEreporter.nih.gov
Cardiac MRI for Reperfusion Spatial Mapping to Improve Heart Failure OutcomesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,024,459July 1, 2023April 30, 2028NGUYEN, KIM-LIEN Treporter.nih.gov
A stress-induced promoter pause release program in cardiomyocytes protecting against myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,021,907December 15, 2019November 30, 2024ROSENFELD, MICHAEL Greporter.nih.gov
Universal optical coherence polarimetryNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,020,013July 15, 2022April 30, 2026VILLIGER, MARTINreporter.nih.gov
Scarring and Arrhythmia in Infarcted Aged Hearts: Role of Senescent FibroblastsNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,019,793January 20, 2019December 31, 2022KOREN, GIDEONreporter.nih.gov
Establishing a Useful and Usable "Out of the Box" Quality Improvement Library for Enhanced Health System Efficiency and OutcomesNIHNational Center for Advancing Translational Sciences2024 to 2025$2,016,276August 16, 2024May 31, 2026TOBIAS, MARCreporter.nih.gov
Cardiovascular effects of oral bicarbonate in CKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,014,849August 24, 2022July 31, 2027RAPHAEL, KALANI LUKELAreporter.nih.gov
Cytoskeletal Control of Yap in Heart RegenerationNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,013,365July 1, 2023June 30, 2027MARTIN, JAMES Freporter.nih.gov
Clinical benefits and mechanism of action of angiotensin-II receptor blocker on Cardiovascular remodeling in patients with repaired coarctation of aortaNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,012,689August 25, 2023July 31, 2028EGBE, ALEXANDERreporter.nih.gov
Comprehensive CT Guided Coronary Artery Bypass Graft SurgeryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,010,927February 15, 2019January 31, 2026NIEMAN, KOENreporter.nih.gov
High-throughput cellular genetics to connect noncoding variants to coronary artery disease genesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,007,839April 1, 2023March 31, 2027GUPTA, RAJAT Mreporter.nih.gov
Sequence Variants Impacting Cardiomyocyte S-phase Activity in Inbred Mice Following InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,007,341February 15, 2021January 31, 2026FIELD, LOREN Jreporter.nih.gov
Troponin I phosphorylation as a novel novel cardiac inotropeNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,003,047April 1, 2023March 31, 2027BIESIADECKI, BRANDON Jreporter.nih.gov
Single-cell, multi-omic investigation of epicardial adipose and coronary endothelial dysfunction in type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$2,002,186September 18, 2024June 30, 2027MAJITHIA, AMITreporter.nih.gov
Cardiac Exosomes in myocardial Ischemic injuryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,000,368April 3, 2020November 30, 2023MUEHLSCHLEGEL, JOCHEN DANIELreporter.nih.gov
Biomedical 600 MHz High Field MR Spectroscopy and Imaging Magnet UpgradeNIHOffice of the Director, National Institutes of Health2025$2,000,000May 1, 2025April 30, 2027ACKERMAN, JEROME Lreporter.nih.gov
SBIR TOPIC 111, PHASE II: A COMPACT PORTABLE MEDICAL OXYGEN GENERATORNIHNational Heart, Lung, and Blood Institute2025$2,000,000September 30, 2025September 29, 2027ALFORD, JOHN Mreporter.nih.gov
Developing a new drug for treating myocardial ischemia/reperfusion injuryNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,998,610September 20, 2021August 31, 2025SKIDGEL, RANDAL Areporter.nih.gov
A Role of PKG1a and Inhibitors of cGMP Phosphodiesterase in Post MI VT in Mouse Models for Type II Diabetes and Metabolic SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,996,226July 1, 2020June 30, 2024GALPER, JONAS BERNARDreporter.nih.gov
The Role of Arylsulfatase in Vascular CalcificationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,995,798April 1, 2023March 31, 2027MALHOTRA, RAJEEVreporter.nih.gov
Examining Susceptibility and Resistance Phenotypes to Enhance Understanding of the Genetic Basis of Major Coronary Artery Disease in Type 1 DiabetesNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,995,149July 27, 2022June 30, 2027MILLER, RACHEL GRACEreporter.nih.gov
Cardiac CT DebloomingNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,994,352September 1, 2020March 15, 2024DE MAN, BRUNOreporter.nih.gov
Pivotal Preclinical Studies of Novel Infusible ECM for Treating Acute MINIHNational Heart, Lung, and Blood Institute2023 to 2024$1,992,340September 15, 2023July 31, 2026KINSEY, ADAM Mreporter.nih.gov
Change of InstitutionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,991,250January 1, 2017June 30, 2024BURNS, CAROLINE Ereporter.nih.gov
PAcific Islander, Native Hawaiian and Asian American Cardiovascular Health Epidemiology (PANACHE) StudyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,989,441August 4, 2023June 30, 2028GO, ALAN Sreporter.nih.gov
Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,988,559May 1, 2020July 31, 2025MCCOLLOUGH, CYNTHIA Hreporter.nih.gov
Validation of Myocardial Oxygen Extraction Fraction Measurement with MRINIHNational Heart, Lung, and Blood Institute2023 to 2025$1,985,848August 15, 2023June 30, 2027ZHENG, JIEreporter.nih.gov
Developing Long Noncoding RNA Therapy for Precision Cardiac RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,982,431April 1, 2019August 31, 2027CHENG, KEreporter.nih.gov
Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease riskNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,981,673August 10, 2023June 30, 2027REILLY, MUREDACH Preporter.nih.gov
Targeting smooth muscle cell BMAL1 as a new therapeutic strategy against restenosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,981,608January 1, 2023December 31, 2026GUO, ZHENHENGreporter.nih.gov
Fibroblast targeting for myocardial repairNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,977,819April 1, 2023March 31, 2027SPINALE, FRANCIS Greporter.nih.gov
Reading workstation for clinical contrast echocardiographyNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,975,527March 1, 2021August 31, 2025SKLENAR, JIRIreporter.nih.gov
Computational and functional strategies to decipher lncRNAs in human atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,972,315February 1, 2020January 31, 2025REILLY, MUREDACH Preporter.nih.gov
Cardioprotective mechanisms of novel noncoding RNA in myocardial infarctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,970,843April 1, 2023March 31, 2027MARBAN, EDUARDOreporter.nih.gov
System-independent quantitative cardiac CT perfusionNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,968,096August 1, 2021July 31, 2025ROY, DEBASHISHreporter.nih.gov
Rapid Comprehensive Cardiac MRI Exam for Diagnosis of Coronary Artery DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,965,752May 26, 2020April 30, 2026AKCAKAYA, MEHMETreporter.nih.gov
Deciphering Myofilament Modifications in Ischemic CardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,963,460March 1, 2013June 30, 2025GE, YINGreporter.nih.gov
Stress, inflammation and coronary endothelial injury in preeclampsiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,961,087September 2, 2022June 30, 2027HAYS, ALLISON Greporter.nih.gov
Targeting Immune-Responsive Gene 1 (Irg1) and Itaconate for Cardioprotection of the Donor Heart for TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,957,180August 1, 2023July 31, 2027TANG, PAULreporter.nih.gov
The role of Sertad4 in pathologic cardiac remodeling.NIHNational Heart, Lung, and Blood Institute2022 to 2025$1,954,389July 1, 2022June 30, 2027STRATTON, MATTHEWreporter.nih.gov
Switch of Osteogenesis in Vascular CalcificationNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,950,000July 1, 2018June 30, 2026YAO, YUCHENGreporter.nih.gov
Sensing and Clearance of Damaged Lysosomes in Macrophages and AtherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,949,485November 4, 2014June 30, 2026RAZANI, BABAKreporter.nih.gov
Deep probabilistic predictive models for stroke and coronary heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,947,508September 1, 2019June 30, 2025RANGANATH, RAJESHreporter.nih.gov
A K63-Ubiquitination Dependent Necroptosis Signaling Network in the HeartNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,943,750January 8, 2021December 31, 2026LIU, QINGHANGreporter.nih.gov
miR-615, AKT/eNOS signaling, and angiogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,942,564May 15, 2020April 30, 2024FEINBERG, MARK Wreporter.nih.gov
Treating secondary cardiomyopathies by mimicking the adaptive hepatic glucose fasting responseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,939,355July 1, 2020July 2, 2024DEBOSCH, BRIAN JESSEreporter.nih.gov
A Novel Driver of Hyperphosphatemia and Vascular Calcification in CKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,934,984December 1, 2020November 30, 2025MIYAZAKI, MAKOTOreporter.nih.gov
Transvenous Optoacoustic-Ultrasound Guided Cold Laser Wire for Crossing Coronary Chronic Total OcclusionNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,934,572May 1, 2022April 30, 2026MILNER, THOMAS Ereporter.nih.gov
Leveraging the mitochondrial regulator MIRO1 to prevent neointimal hyperplasiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,926,265December 1, 2021May 31, 2025GRUMBACH, ISABELLA MARIAreporter.nih.gov
Circadian Rhythm as a Therapeutic Target for Perioperative CardioprotectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,925,827May 11, 2023April 30, 2027ELTZSCHIG, HOLGER K.reporter.nih.gov
Ischemia/Reperfusion injury and Myocardial edemaNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,915,267July 1, 2023June 30, 2027SIMONS, MICHAELreporter.nih.gov
Engineering a cross-linked cellular network for cardiac repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,912,343September 1, 2022August 31, 2026NGUYEN, JULIANEreporter.nih.gov
Molecular Drivers of Atherosclerosis in DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,910,575September 18, 2024June 30, 2027ONENGUT, SUNAreporter.nih.gov
Molecular Mechanisms of TRIB1 Regulation of Hepatic MetabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,907,161May 1, 2023April 30, 2027BAUER, ROBERT CLAYTONreporter.nih.gov
Preclinical imaging of immune responses to chronic stressNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,905,800July 1, 2023June 30, 2028VAN LEENT, MANDY MARIA THERESIAreporter.nih.gov
Engineered BacNav and BacCav for Improved Excitability and ContractionNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$1,900,343May 1, 2022January 31, 2027BURSAC, NENADreporter.nih.gov
Cell Plasticity-Based Reprogramming Strategies to Enhance Human Myocardial RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,895,277April 1, 2020March 31, 2025ROSENGART, TODD Kreporter.nih.gov
Angiogenic Bioengineered Systems to Optimize Post-Infarction Myocardial RecoveryNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,891,065March 15, 2008February 28, 2026WOO, Y JOSEPHreporter.nih.gov
Rehabilitation at home using mobile health in older adults after hospitalization for ischemic heart disease (RESILIENT)NIHNational Institute on Aging2021 to 2023$1,890,893July 15, 2019April 30, 2025DODSON, JOHN Areporter.nih.gov
Clinical and Molecular Epidemiology of High Risk Coronary PlaqueNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,889,754August 1, 2019July 31, 2024SHAH, SVATI H.reporter.nih.gov
Coronary artery dysfunction in OSA: Role of mineralocorticoid receptorsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,880,847June 1, 2023May 31, 2028BADRAN, MOHAMMADreporter.nih.gov
Genetic Prediction for Treatment Resistance in Kawasaki DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,880,732December 15, 2018November 30, 2023PORTMAN, MICHAEL Areporter.nih.gov
Genetics of Cardiovascular Disease in Chronic Kidney DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,872,629May 1, 2022April 30, 2026FRANCESCHINI, NORAreporter.nih.gov
Neural Inflammation and Exercise Pressor Reflex in Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,872,119August 16, 2023June 30, 2027WANG, HANJUNreporter.nih.gov
The transcriptional control of vascular calcification in diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,865,635March 15, 2023February 28, 2027MIYAZAKI, MAKOTOreporter.nih.gov
Effectiveness of Strategies to Improve Outcomes after Hospitalization for Acute Myocardial Infarction in Older AdultsNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,862,346March 1, 2022February 28, 2026CHAUDHRY, SARWAT Ireporter.nih.gov
Vascular calcification and atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,860,950January 1, 2021December 31, 2026SAVINOVA, OLGA V.reporter.nih.gov
AI-based Cardiac CTNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,859,635May 1, 2023February 28, 2028YU, HENGYONGreporter.nih.gov
1/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)NIHNational Heart, Lung, and Blood Institute2024$1,858,859September 25, 2024August 31, 2025PATEL, MANESH Rreporter.nih.gov
Prevent Unnecessary Carotid Intervention and Stroke using Noninvasive Transcutaneous Ultrasound Thermal Strain Imaging (US-TSI)NIHNational Heart, Lung, and Blood Institute2021 to 2023$1,858,255June 15, 2020May 31, 2025KIM, KANGreporter.nih.gov
Metabolic and Transcriptional Reprogramming of Cardiac MaturationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,853,015April 1, 2021March 31, 2025MURRY, CHARLES Ereporter.nih.gov
1/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)NIHNational Heart, Lung, and Blood Institute2025$1,841,946September 25, 2024August 31, 2029PATEL, MANESH Rreporter.nih.gov
Clonal hematopoiesis of indeterminate potential and HIV in the REPRIEVE trialNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,838,919September 1, 2020August 31, 2024NATARAJAN, PRADEEPreporter.nih.gov
Effect of Cardioplegia and Cardiopulmonary Bypass on Coronary Microvascular ReactivityNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,835,874August 1, 1992March 31, 2026SELLKE, FRANK Wreporter.nih.gov
Therapeutic Potential of Estrogen-Regulated Metabolism and Cardiovascular RiskNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,835,045March 1, 2016April 30, 2025STAFFORD, JOHN MICHAELreporter.nih.gov
Metabolic regulation of myocardial perfusion in the aging heartNIHNational Institute on Aging2025$1,828,658September 15, 2024August 31, 2029HILL, BRADFORD GUYreporter.nih.gov
Systems Genetics of Vascular Smooth Muscle PhenotypesNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,820,349December 15, 2022June 30, 2025CIVELEK, METEreporter.nih.gov
Macrophage functional dynamics in adult heart regenerationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,817,380April 1, 2023March 31, 2027LIU, JIANDONGreporter.nih.gov
Using Genetics to Inform Mechanism of Cardiovascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,814,970February 1, 2017June 30, 2022WILLER, CRISTEN Jreporter.nih.gov
The Role of Notch Signaling in Type 2 Diabetic Coronary Microvascular DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,813,049April 1, 2023March 31, 2027TRASK, AARON Jreporter.nih.gov
The role of microglia Nek6 in myocardial infarction-induced cognitive impairmentNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,805,517July 1, 2020June 30, 2025DUTTA, PARTHAreporter.nih.gov
Sensing Vulnerable Plaque in vivo by an All-optical Intravascular Ultrasound and Photoacoustic CatheterNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,804,444August 1, 2015August 31, 2025CHENG, JI-XINreporter.nih.gov
Cardiac Pathophysiology of Proteasome PhosphoregulationNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,800,966September 1, 2020April 30, 2029WANG, XUEJUNreporter.nih.gov
Expansion of Percutaneous Coronary Intervention in Outpatient and Inpatient Settings: Quantifying the Differential Impact Between Disadvantaged and Non-Disadvantaged CommunitiesNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,799,520July 1, 2016June 30, 2027HSIA, RENEE YUEN-JANreporter.nih.gov
Opportunistic Atherosclerotic Cardiovascular Disease Risk Estimation at Abdominal CTs with Robust and Unbiased Deep LearningNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,796,488September 1, 2023May 31, 2028CHAUDHARI, AKSHAYreporter.nih.gov
Anti-Inflammatory Roles and Macrophage Metabolism of Lactate and Ketones during Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,789,958August 11, 2023July 31, 2028MOUTON, ALAN Jreporter.nih.gov
FAT cadherins and vascular remodelingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,780,272December 15, 2022November 30, 2026SIBINGA, NICHOLAS Ereporter.nih.gov
Hippo and Wnt Signaling in Cardiac RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,766,058January 15, 2016December 31, 2024MARTIN, JAMES Freporter.nih.gov
IND-enabling Epicardial Biopharmaceutical in the Diabetic HeartNIHNational Heart, Lung, and Blood Institute2021$1,760,696August 15, 2018January 31, 2023RUIZ-LOZANO, PILARreporter.nih.gov
Role of de novo pyrimidine biosynthesis in pathological cardiac remodelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,760,000March 1, 2022February 28, 2027WANG, ZHAOreporter.nih.gov
The role of pericytes in scar formation following stroke and myocardial infarctionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,758,240March 1, 2020February 28, 2025CARMICHAEL, STANLEY THOMASreporter.nih.gov
Role of ROCK isoform-mediated actin cytoskeleton modification in the pathogenesis of heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,755,090January 15, 2021December 31, 2025WEI, LEIreporter.nih.gov
Ferroptosis in the Heart: Iron Calcium Crosstalk and CompartmentalizationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,751,600December 25, 2021November 30, 2026XIE, LAI-HUAreporter.nih.gov
MMP responsive polymeric materials for treating acute myocardial infarctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,747,774September 1, 2017June 30, 2027CHRISTMAN, KAREN Lreporter.nih.gov
Myeloid cells are critical in inflammatory heart diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,747,535February 1, 2014June 30, 2025CIHAKOVA, DANIELAreporter.nih.gov
Cardiac protective mechanisms of melanocortin system activationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,747,424January 9, 2023December 31, 2026SILVA, ALEXANDRE ALVES DAreporter.nih.gov
Mechanisms of Cell-Based Heart RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,742,404April 1, 2019March 31, 2025SNIADECKI, NATHAN JOHNreporter.nih.gov
Novel Mechanisms that Restore Cardiac Parasympathetic Activity Limits Arrhythmias and Cardiac Dysfunction After Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,740,413April 10, 2020March 31, 2026MENDELOWITZ, DAVIDreporter.nih.gov
Targeting Residual ASCVD Risk by Integrating Genetics and Clinical DataNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,736,459July 15, 2024June 30, 2028WEI, WEI-QIreporter.nih.gov
Investigation of Partial Electrical Nerve Block for Autonomic RegulationNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,729,684January 6, 2020December 31, 2025VRABEC, TINA LOUISEreporter.nih.gov
Cardiac afferents and renal function in heart failureNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,714,995December 18, 2015December 31, 2024ZUCKER, IRVING Hreporter.nih.gov
HLS-Development of a cardiac ischemia model in an organ-on-a-chip platformNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,709,530September 1, 2018February 28, 2025SHULER, MICHAEL Lreporter.nih.gov
The Effects of Bundled Payment on Acute Cardiovascular Outcomes Among Older AdultsNIHNational Institute on Aging2023 to 2025$1,707,931September 1, 2015March 31, 2027RYAN, ANDREW Mreporter.nih.gov
Innovative Voltage-Activated Ultrasound Imaging Agent for Selective Myocardial EnhancementNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,707,452July 1, 2021June 30, 2024CIMORELLI, MICHAELreporter.nih.gov
Administrative Supplement to 7R01HL148060-03 Titled: Opposing Effects of Prostaglandin E2 EP3 and EP4 Receptors on MitochondrialNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,697,970April 15, 2020January 31, 2024HARDING, PAMELAreporter.nih.gov
Biomimetic Vascular Matrix for Vascular Smooth Muscle Cell Mechanobiology and PathologyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,696,127September 1, 2023June 30, 2027BAE, YONGHOreporter.nih.gov
A dialogue between neutrophils and monocytes for effective resolution of inflammation following acute myocardial injuryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,695,891July 1, 2022June 30, 2027NAGAREDDY, PRABHAKARA REDDYreporter.nih.gov
Restoration and Function of S-Nitrosothiol in Stored BloodNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,690,342December 1, 2016January 31, 2028STAMLER, JONATHAN S.reporter.nih.gov
Dysregulations in Polyamine Metabolism During AtherosclerosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,688,538April 1, 2023March 31, 2028YURDAGUL, ARIFreporter.nih.gov
STK25 phosphorylates PRKAR1A to regulate PKA signalingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,687,751August 1, 2023June 30, 2028FINE, BARRY M.reporter.nih.gov
Tai Chi Exercise and Wearable Feedback Technology to Promote Physical Activity in ACS SurvivorsNIHNational Center for Complementary & Integrative Health2022 to 2025$1,684,273September 5, 2022August 31, 2026YEH, GLORIA Yreporter.nih.gov
Studying Atherosclerosis Macrophage Dynamics by Combined PET and Fluorine-MRINIHNational Heart, Lung, and Blood Institute2021 to 2022$1,682,636January 15, 2019December 31, 2023FAYAD, ZAHI A.reporter.nih.gov
Restoration of myocardial reparative function of diabetic progenitor cells by epigenetic modulationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,680,897December 10, 2019November 30, 2025KISHORE, RAJreporter.nih.gov
Novel Inhibitors for Temporal Modulation of T-Lymphocytes during Chronic Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,680,264July 1, 2023June 30, 2027BANSAL, SHYAM SUNDERreporter.nih.gov
Acid, Succinate and Glyoxal Metabolism in IschemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,675,811July 1, 2003September 30, 2026BROOKES, PAUL Sreporter.nih.gov
Targeting the Sirt-1 pathway to modulate inflammation during murine Kawasaki Disease vasculitisNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,670,000July 1, 2021June 30, 2025NOVAL RIVAS, MAGALIreporter.nih.gov
The role of GATA3-positive macrophages in cardiovascular pathologiesNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,670,000July 1, 2022June 30, 2026SHAH, PREDIMAN KRISHANreporter.nih.gov
Mechanisms of sex-biased risk and resiliency in aneurysm and dissectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,670,000September 16, 2022August 31, 2026PARKER, SARAH Jreporter.nih.gov
Arterial Inflammation and Coronary Microvascular Dysfunction among Women with HIV: Missing Pieces to the MI Risk PuzzleNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,666,593August 9, 2019July 31, 2025ZANNI, MARKELLA V.reporter.nih.gov
The function of Runx1 in cardiac fibroblasts and post-myocardial infarction healingNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,661,047December 1, 2021November 30, 2026FU, XINGreporter.nih.gov
Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,658,695April 22, 2020September 22, 2023MOHAMED, TAMER M Areporter.nih.gov
A mixed methods study to identify and refine implementation strategies to increase use of cardiac rehabilitation for patients with heart failureNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,657,051May 25, 2021February 28, 2025LAGU, TARA Creporter.nih.gov
SUMO2-p66shc axis in vascular endothelial dysfunction and atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,651,874April 1, 2020March 31, 2026KUMAR, SANTOSHreporter.nih.gov
Molecular Regulation of AtherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,645,376February 1, 2019January 31, 2025CHEN, HONGreporter.nih.gov
PFAS accelerate atherosclerosis through modulation of bile acid metabolismNIHNational Institute of Environmental Health Sciences2023$1,644,161September 19, 2023August 31, 2026PETRIELLO, MICHAEL CURTISreporter.nih.gov
Targeting cardiac fibroblast-myocyte cross talk to enhance heart function after cardiac injuryNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,638,000September 2, 2020August 31, 2025DEB, ARJUNreporter.nih.gov
Cardiac AAV gene delivery for clinical translationNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,637,150April 2, 2024January 31, 2029ISHIKAWA, KIYOTAKEreporter.nih.gov
Impact of the COVID-19 pandemic, SARS-CoV-2 infection and social determinants of health on pregnancy complications, birth outcomes and post-pregnancy maternal cardiovascular and mortality outcomesNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,632,961April 1, 2022March 31, 2026MALEK, ANGELA Mreporter.nih.gov
Dysregulated Adiponectin Transmembrane Signaling in Diabetic CoronaryVascular Injury and Heart FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,628,214February 1, 2022January 31, 2027WANG, YAJINGreporter.nih.gov
Circadian regulation of vascular agingNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,628,142January 18, 2019December 31, 2024CHEN, YABINGreporter.nih.gov
Comparing a Novel Telehealth-enabled Hybrid Cardiac Rehabilitation Program to Clinic-based Cardiac Rehabilitation for Improving Patient Engagement and Functional Outcomes after ACSNIHNational Institute on Minority Health and Health Disparities2024 to 2025$1,628,101September 20, 2024May 31, 2029DURAN, ANDREA Treporter.nih.gov
The Role of Food Sensitization in Cardiovascular DiseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,626,865August 13, 2024July 31, 2029KEET, CORINNEreporter.nih.gov
TNFR1 Expressing Exosomes are Critical Mediators of Pathological Immune Activation in the Spleen post-Myocardial InfarctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,624,306September 7, 2021July 31, 2027BANSAL, SHYAM SUNDERreporter.nih.gov
Mechanistic registry to study whether infection with Corona Virus Disease 2019 (COVID-19) alters atherosclerotic plaque progressionNIHNational Heart, Lung, and Blood Institute2021$1,620,596September 6, 2021September 7, 2021SHAW, LESLEE Jreporter.nih.gov
Understanding the role of mitochondrial dysfunction in cardiac arrhythmias using a novel 3D panoramic optical mapping systemNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,620,000April 1, 2020March 31, 2025WAN, ELAINE Yreporter.nih.gov
Novel Neural Mechanisms underlying Lung-Heart Pathological CrosstalkNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,617,138April 1, 2020March 31, 2025WANG, HANJUNreporter.nih.gov
DYRK1a as a therapeutic target to treat myocardial infarctionNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,615,000August 15, 2021July 31, 2025WOLF, MATTHEW Jreporter.nih.gov
Targeting Endothelial Epsins to Ameliorate Myocardial IschemiaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,609,612July 8, 2024June 30, 2028CHEN, HONGreporter.nih.gov
Clonal Hematopoiesis in Healthy Individuals from Families with Early OnsetCoronary Artery DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,606,957May 1, 2019April 30, 2025BECKER, LEWIS Creporter.nih.gov
Simple and Effective Laceration of Potentially-calcified Leaflets as an Adjunct to Transcatheter Valve ReplacementNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,606,814January 20, 2024December 31, 2027DUPONT, PIERRE Ereporter.nih.gov
NKA/CD36 signaling in adipocytes promotes oxidative stress and drives chronic inflammation in atherosclerosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,604,907April 1, 2023March 31, 2027SILVERSTEIN, ROY Lreporter.nih.gov
Effect of CTHRC1 on endothelial cell survival after acute ischemiaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,603,728December 20, 2019November 30, 2025LINDNER, VOLKHARDreporter.nih.gov
Unique value of real-time shear stress to enhance coronary disease managementNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,603,334January 1, 2018December 31, 2024TEARNEY, GUILLERMO Jreporter.nih.gov
Enhancing Autophagy and Mitochondrial Biogenesis to Mitigate Cardiac Reperfusion InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,600,586July 1, 2020June 30, 2026XIE, MINreporter.nih.gov
CARDIA Year 35 Brain MRI RenewalNIHNational Institute on Aging2021 to 2022$1,599,247September 15, 2019May 31, 2025BRYAN, R Nreporter.nih.gov
Cardiac delivery of RNA to treat contractile disorderNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,590,483July 1, 2024April 30, 2028MARGULIES, KENNETH BERreporter.nih.gov
Mechanisms of myocardial regeneration mediated by Nkx2.5 in zebrafishNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,578,254April 1, 2023March 31, 2028TARGOFF, KIMARA Lreporter.nih.gov
q4DE: A Biomarker for Image-Guided, Post-MI Hydrogel TherapyNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,576,624February 18, 2014February 28, 2025DUNCAN, JAMES Sreporter.nih.gov
Lipidation and Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,575,000April 21, 2021March 31, 2026SEMENKOVICH, CLAY F.reporter.nih.gov
Targeting Adiponectin for Cardioprotection in the Ischemic HeartNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,574,916May 1, 2010November 30, 2025MA, XIN-LIANGreporter.nih.gov
Molecular control of ischemia-induced tissue fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,573,551July 1, 2020June 30, 2025YU, JUNreporter.nih.gov
Macrophage Inflammarafts and Mitochondrial Dysfunction in AtherosclerosisNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,571,556February 1, 2024January 31, 2028MILLER, YURYreporter.nih.gov
An Information tecHnology approach to implEmenting depression treAtment in caRdiac patienTs: [iHeart Trial]NIHNational Heart, Lung, and Blood Institute2021 to 2022$1,570,899April 1, 2018March 31, 2025MOISE, NATHALIEreporter.nih.gov
Modeling of cell-specific LRP1 signaling in acute myocardial infarctionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,568,092August 12, 2024April 30, 2028SAUCERMAN, JEFFREY J.reporter.nih.gov
Risk Factors for CVD in WomenNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,562,202December 1, 1984May 31, 2024MANSON, JOANN ELISABETHreporter.nih.gov
Printed Electronic Biosensors for Point-of-Care Testing of Cardiovascular BiomarkersNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,558,958April 15, 2019March 31, 2025FRANKLIN, AARONreporter.nih.gov
The methyltransferase Smyd1 regulates cardiac physiologyNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,558,425July 15, 2022June 30, 2027FRANKLIN, SARAHreporter.nih.gov
Air Pollution, Coronary Events and Atherosclerotic Progression in a Susceptible PopulationNIHNational Institute of Environmental Health Sciences2021 to 2025$1,558,412July 21, 2021April 30, 2027WANG, MENGreporter.nih.gov
Immune mechanisms of influenza‐induced exacerbation of atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,558,220August 15, 2020July 31, 2025GOPAL, RADHAreporter.nih.gov
Cardiac Macrophages as Disease Drivers in Chronic Ischemic Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,556,464April 1, 2021March 31, 2026PRABHU, SUMANTH Dreporter.nih.gov
The Deubiquitinase CYLD Controls Multiple Cell Death Pathways in the HeartNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,555,000April 1, 2022March 31, 2027LIU, QINGHANGreporter.nih.gov
Novel sphingolipid metabolites in myocardial ischemiaNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,552,500July 7, 2020June 30, 2025COWART, LAUREN ASHLEYreporter.nih.gov
ApoE receptor-2 in vascular disease progression and regressionNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,551,783April 1, 2019March 31, 2024HUI, DAVID YIU-KWANreporter.nih.gov
Patient-Specific Simulations to Guide Coronary Bifurcation StentingNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,549,766April 15, 2019January 17, 2023CHATZIZISIS, IOANNIS Sreporter.nih.gov
IDOL and dyslipidemia in cardiovascular diseasesNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,547,876September 1, 2019July 31, 2024CHEN, YUQING EUGENEreporter.nih.gov
Genetic modulation of inflammation following myocardial infarctionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,547,467September 1, 2024June 30, 2029GUMINA, RICHARD Jreporter.nih.gov
Surgical Microneedle Patch Delivery of CMMP for Heart RepairNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,542,902April 20, 2020June 30, 2023CHENG, KEreporter.nih.gov
Calciprotein Particles and Vascular Calcification in Patients with Chronic Kidney DiseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,540,142January 1, 2024December 31, 2028CHEN, WEIreporter.nih.gov
Intravascular NIRF-IVUS imaging of inflammation-guided arterial therapyNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,538,825March 17, 2020February 28, 2025JAFFER, FAROUC AMINreporter.nih.gov
Epigenomic signaling and heart failure.NIHNational Heart, Lung, and Blood Institute2021 to 2023$1,538,638December 6, 2019November 30, 2025CHANG, JIANGreporter.nih.gov
IL1beta signaling in SMCpromotes beneficial changes in late stage atherosclerotic lesion pathogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,537,348February 1, 2019January 31, 2024OWENS, GARY Kreporter.nih.gov
Mechanistic Insights to A Translatable Therapy for Acute Reperfused Hemorrhagic Myocardial InfarctionsNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,535,864March 5, 2020February 28, 2025DHARMAKUMAR, ROHANreporter.nih.gov
Vascular-targeted Atheroprotective Gene therapies to Prevent Vein Graft FailureNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,529,131May 25, 2024February 28, 2028FERRAN, CHRISTIANEreporter.nih.gov
Measurement and Reduction of Low-Value Cardiovascular CareNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,526,692April 1, 2024February 28, 2029KINI, VINAYreporter.nih.gov
Effects of SGLT2 Inhibition on Coronary Flow Reserve and Other Key Indices Relevant to Type 2 Myocardial Infarction Risk among Women with HIVNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,524,171September 1, 2024August 31, 2029ZANNI, MARKELLA V.reporter.nih.gov
LONGITUDINAL ASSOCIATION OF POST-INFARCT LIPOMATOUS METAPLASIA AND MALIGNANT ARRHYTHMIANIHNational Heart, Lung, and Blood Institute2024 to 2025$1,524,018August 1, 2024July 31, 2029NAZARIAN, SAMANreporter.nih.gov
Role of collagen heterogeneity in remodeling of acute and chronic heart scarsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,521,000July 1, 2020June 30, 2025DEB, ARJUNreporter.nih.gov
Ca2+ and ROS Crosstalk Signaling in Cardiac MitochondriaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,520,640January 1, 2010November 30, 2025SHEU, SHEY-SHINGreporter.nih.gov
Role of the mitochondrial LonP1 in myocardial ischemia and reperfusion injury protectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,520,000June 10, 2022May 31, 2027SUNDARARAJAN, VENKATESHreporter.nih.gov
Drug Delivery and Biomimetic Approaches for Optimal Stem Cell TherapyNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,518,930April 1, 2021March 31, 2025CHENG, KEreporter.nih.gov
Epigenetic reprogramming of cardiac myofibroblasts for cardiac repairNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,516,842July 1, 2023June 30, 2027TANG, YAO LIANGreporter.nih.gov
Preventing Myocardial Events of Aging: A PREVENTABLE Ancillary StudyNIHNational Institute on Aging2024 to 2025$1,512,879February 1, 2024November 30, 2028GOYAL, PARAGreporter.nih.gov
Aptamer-functionalized cardiac patchesNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,510,900August 1, 2015May 31, 2025WANG, YONGreporter.nih.gov
Brain-immune crosstalk in myocardial infarctionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,510,152May 1, 2023April 30, 2028POLLER, WOLFRAM CHRISTIANreporter.nih.gov
T Lymphopenia in Ischemic Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,507,767July 1, 2022June 30, 2027MA, YONGGANGreporter.nih.gov
RISK FACTORS FOR CVD IN WOMENNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,506,545December 1, 1984August 31, 2028QI, LUreporter.nih.gov
Comparing hospitalization rates, outcomes, and treatment intensity for elderly patients across OECD countriesNIHNational Institute on Aging2022 to 2024$1,502,864July 1, 2019March 31, 2026LANDON, BRUCE E.reporter.nih.gov
Mechanisms that Govern and Promote Cardiovascular RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,502,316July 10, 2019June 30, 2024GARRY, DANIEL J.reporter.nih.gov
Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular HealthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,502,009September 1, 2021August 2, 2022SHUFELT, CHRISANDRA LEEreporter.nih.gov
The role of Pitx2 in heart injury and regeneration.NIHNational Heart, Lung, and Blood Institute2021 to 2024$1,495,000April 1, 2020March 31, 2026TAO, GEreporter.nih.gov
Post-Transcriptional Regulation of Gene Expression by Ribosome-Binding Protein 1NIHNational Heart, Lung, and Blood Institute2024 to 2025$1,494,652May 10, 2024April 30, 2029DOROUDGAR, SHIRINreporter.nih.gov
Collagen-derived peptides to target inflammation in myocardial infarctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,489,669December 15, 2021November 30, 2026DE CASTRO BRAZ, LISANDRA Ereporter.nih.gov
Noninvasive Testing of Coronary Microvascular Reactivity Using High-resolution Free-breathing MRINIHNational Heart, Lung, and Blood Institute2022 to 2024$1,489,262July 15, 2020November 1, 2024SHARIF, BEHZADreporter.nih.gov
SNRK in ischemic vascular diseasesNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,489,006April 1, 2018April 30, 2023XIE, ZHONGLINreporter.nih.gov
Minimizing myocardial damage and loss of cardiac function post myocardial infarction using Targeted PKC inhibitors 002 and 004.NIHNational Heart, Lung, and Blood Institute2025$1,488,899April 1, 2025December 31, 2026YOUNG, LINDON Hreporter.nih.gov
Stellate Ganglia Nrf2 Signaling and Enhanced Cardiac Sympathetic Tone in Chronic Heart FailureNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,483,024September 1, 2024August 31, 2028WANG, HANJUNreporter.nih.gov
Predictive and systems modeling of exosome cargoNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,483,018January 1, 2019December 31, 2023DAVIS, MICHAEL Ereporter.nih.gov
Impact of L. plantarum 299v Supplementation on Endothelial Function and Systemic InflammationNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,482,252March 22, 2019January 31, 2025WIDLANSKY, MICHAEL Ereporter.nih.gov
Biphasic Regulation of Endothelial Transdifferentiation by Alcohol and Its Impact on Vascular DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,481,378September 20, 2023August 31, 2028REDMOND, EILEEN M.reporter.nih.gov
Inhalable stem cell exosome therapy for cardiac injuryNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,478,554June 4, 2024May 31, 2028CHENG, KEreporter.nih.gov
Novel Gene Therapy For Chronic Ischemic Heart FailureNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,477,192January 16, 2024December 31, 2027SHAW, ROBIN Mreporter.nih.gov
Novel methodologies to improve coronary artery disease diagnostics with dynamic PETNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,476,019July 1, 2024June 30, 2029TANG, JINGreporter.nih.gov
The Effects of Changing Health Care Markets on Cardiovascular and Cerebrovascular Care and OutcomesNIHNational Institute on Aging2024 to 2025$1,474,883September 15, 2024August 31, 2029ZACHRISON, KORILYN SAUSERreporter.nih.gov
Targeted Anti-IL-1β Platelet Mimetics for Cardiac Detoxification and RepairNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,472,172April 1, 2015March 31, 2024CHENG, KEreporter.nih.gov
Biomimetic nanomaterials for the immunomodulation of the cardiosplenic axis post-myocardial infarctionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,471,030July 1, 2024June 30, 2028MENICK, DONALD R.reporter.nih.gov
Adenine metabolism in cardiac repairNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,470,265July 25, 2024April 30, 2028DEB, ARJUNreporter.nih.gov
Per- and polyfluoroalkyl substances, apolipoproteins, and risk of coronary heart diseaseNIHNational Institute of Environmental Health Sciences2024 to 2025$1,468,436April 16, 2024January 31, 2029SUN, QIreporter.nih.gov
CARDIA CHICAGO FC - TASK AREA A PERIOD OF PERFORMANCE OPY 1: 07/01/2019 - 06/30/2020NIHNational Heart, Lung, and Blood Institute2021 to 2022$1,466,802July 1, 2018June 30, 2023LLOYD-JONES, DONALDreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Massachusetts General HospitalBoston, MA53$86.6 million0$0
Stanford UniversityStanford, CA49$52.7 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA28$50.7 million0$0
University of Mississippi Med CTRJackson, MS11$46.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC25$45.7 million0$0
University of VirginiaCharlottesville, VA30$44.3 million0$0
University of California Los AngelesLos Angeles, CA29$42.6 million0$0
Brigham and Women's HospitalBoston, MA30$41.7 million0$0
New York University School of MedicineNew York, NY18$39.3 million0$0
Duke UniversityDurham, NC25$38.7 million0$0
Yale UniversityNew Haven, CT27$34.6 million0$0
Columbia University Health SciencesNew York, NY24$31.7 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA29$31.3 million0$0
University of California, San DiegoLa Jolla, CA19$30.5 million0$0
University of Alabama at BirminghamBirmingham, AL27$30.5 million0$0
Washington UniversitySaint Louis, MO23$30.3 million0$0
Weill Medical Coll of Cornell UnivNew York, NY17$30 million0$0
University of PennsylvaniaPhiladelphia, PA23$29.2 million0$0
University of WashingtonSeattle, WA24$29 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY22$28.5 million0$0
Boston Children's HospitalBoston, MA14$24.4 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA6$24.3 million0$0
University of California, San FranciscoSan Francisco, CA20$23.8 million0$0
Albert Einstein College of MedicineBronx, NY15$23.8 million0$0
University of MinnesotaMinneapolis, MN15$22.6 million0$0
Medical College of WisconsinMilwaukee, WI20$22 million0$0
Baylor College of MedicineHouston, TX17$21.1 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA16$20.5 million0$0
Emory UniversityAtlanta, GA15$20.3 million0$0
Northwestern University at ChicagoChicago, IL16$20 million0$0
University of CincinnatiCincinnati, OH16$19.5 million0$0
University of Nebraska Medical CenterOmaha, NE14$19.5 million0$0
Vanderbilt University Medical CenterNashville, TN10$19 million0$0
Johns Hopkins UniversityBaltimore, MD19$19 million0$0
Mayo Clinic RochesterRochester, MN12$17.6 million0$0
Wake Forest University Health SciencesWinston-Salem, NC7$15.6 million0$0
Indiana University IndianapolisIndianapolis, IN13$15.4 million0$0
University of LouisvilleLouisville, KY17$15.3 million0$0
Augusta UniversityAugusta, GA7$15.3 million0$0
Ohio State UniversityColumbus, OH16$13.4 million0$0
Chapman UniversityOrange, CA1$12.7 million0$0
University of IowaIowa City, IA10$12.6 million0$0
University of Colorado DenverAurora, CO10$12.1 million0$0
Virginia Commonwealth UniversityRichmond, VA9$11.9 million0$0
University of Michigan at Ann ArborAnn Arbor, MI14$11.2 million0$0
Case Western Reserve UniversityCleveland, OH9$10.8 million0$0
University of Illinois at ChicagoChicago, IL7$10.8 million0$0
Mayo Clinic ArizonaScottsdale, AZ6$10.7 million0$0
Rhode Island HospitalProvidence, RI10$10.7 million0$0
Ut Southwestern Medical CenterDallas, TX16$10.7 million0$0
University of Maryland BaltimoreBaltimore, MD9$10.5 million0$0
Cardiac RSK3 Inhibitors, LLCLos Altos, CA3$10.2 million0$0
Beth Israel Deaconess Medical CenterBoston, MA8$9.3 million0$0
Oregon Health & Science UniversityPortland, OR8$9.2 million0$0
University of RochesterRochester, NY11$8.8 million0$0
Kaiser Foundation Research InstituteOakland, CA3$8.7 million0$0
University of ArizonaTucson, AZ11$8.6 million0$0
North Carolina State UniversityRaleigh, NC7$8.6 million0$0
University of UtahSalt Lake City, UT9$8.4 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX8$8.2 million0$0
Thomas Jefferson UniversityPhiladelphia, PA8$8 million0$0
Brown UniversityProvidence, RI7$7.8 million0$0
University of California at DavisDavis, CA4$7.8 million0$0
University of South FloridaTampa, FL9$7.3 million0$0
University of California-IrvineIrvine, CA5$7.3 million0$0
Tufts Medical CenterBoston, MA5$7.2 million0$0
Joslin Diabetes CenterBoston, MA3$7.1 million0$0
University of Missouri-ColumbiaColumbia, MO4$6.9 million0$0
Columbia UniversityNew York, NY5$6.8 million0$0
Tougaloo CollegeTougaloo, MS2$6.6 million0$0
SUNY at BuffaloAmherst, NY7$6.4 million0$0
University of Southern CaliforniaLos Angeles, CA5$6.4 million0$0
University of Wisconsin-MadisonMadison, WI8$6.3 million0$0
George Washington UniversityWashington, DC4$6.3 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA4$6.2 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ6$6.1 million0$0
Medical University of South CarolinaCharleston, SC7$6.1 million0$0
Boston University Medical CampusBoston, MA2$6 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH6$5.8 million0$0
University of TX MD Anderson Can CTRHouston, TX3$5.4 million0$0
University of FloridaGainesville, FL6$5.3 million0$0
Jackson State UniversityJackson, MS2$5.1 million0$0
Tulane University of LouisianaNew Orleans, LA4$4.9 million0$0
Apt Therapeutics, Inc.Naperville, IL1$4.7 million0$0
Clemson UniversityClemson, SC6$4.6 million0$0
University of ChicagoChicago, IL7$4.4 million0$0
Texas A&m University Health Science CTRCollege Station, TX5$4.3 million0$0
Louisiana State Univ HSC ShreveportShreveport, LA6$4.3 million0$0
General Electric Global Research CTRNiskayuna, NY2$4.2 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH4$4.1 million0$0
Northwestern UniversityChicago, IL1$4.1 million0$0
Northeast Ohio Medical UniversityRootstown, OH5$4 million0$0
Georgia State UniversityAtlanta, GA4$4 million0$0
Wayne State UniversityDetroit, MI3$3.8 million0$0
Crossliner INCKalamazoo, MI1$3.8 million0$0
MainehealthPortland, ME3$3.8 million0$0
Texas Tech University Health Scis CenterLubbock, TX2$3.5 million0$0
Mount Sinai Medical Center (miami Beach)Miami Beach, FL2$3.5 million0$0
Texas Heart InstituteHouston, TX4$3.4 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA4$3.4 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025599$366,832,8740$0
2024614$346,539,0150$0
2023648$383,389,0590$0
2022685$363,482,8820$0
2021675$349,420,3440$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 16 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.837December 3, 2026Not listedSame assistance listing 93.837 as 1,147 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.837December 3, 2026Not listedSame assistance listing 93.837 as 1,147 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.837December 4, 2026Not listedSame assistance listing 93.837 as 1,147 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.837January 5, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.837January 5, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.837January 7, 2027$375,000Same assistance listing 93.837 as 1,147 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.837January 7, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)PAR-25-025NIH93.837February 3, 2027$1.5 millionSame assistance listing 93.837 as 1,147 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)PAR-25-026NIH93.837February 3, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)PAR-27-125NIH93.837February 16, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)RFA-DK-27-108NIH93.837March 10, 2027$500,000Same assistance listing 93.837 as 1,147 awards here
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)PAR-25-032NIH93.837March 16, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.837April 5, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.837April 5, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)RFA-OD-25-003NIH93.837April 9, 2027$200,000Same assistance listing 93.837 as 1,147 awards here
NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)RFA-HL-26-002NIH93.837April 28, 2027Not listedSame assistance listing 93.837 as 1,147 awards here
NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)RFA-HL-26-003NIH93.837April 28, 2027Not listedSame assistance listing 93.837 as 1,147 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.