Data / Research funding / Geroscience
Geroscience: 313 NIH awards ($519.5M) to 132 organizations
313 NIH awards ($519.5M) in the NIH spending category Geroscience, to 132 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
313 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical Trial | NIH | National Institute on Aging | 2021 to 2025 | $28,784,116 | August 15, 2019 | April 30, 2027 | BRINTON, ROBERTA EILEEN | reporter.nih.gov |
| Metformin in Alzheimer's dementia Prevention (MAP) | NIH | National Institute on Aging | 2021 to 2025 | $24,224,790 | August 15, 2019 | April 30, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | NIH | National Institute on Aging | 2021 to 2025 | $15,514,157 | September 30, 2021 | May 31, 2027 | ELLERBY, LISA M | reporter.nih.gov |
| Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategies | NIH | National Institute on Aging | 2022 to 2025 | $14,689,794 | September 15, 2019 | December 31, 2026 | PERLS, THOMAS T | reporter.nih.gov |
| BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a Trial | NIH | National Institute on Aging | 2021 to 2025 | $9,481,336 | February 15, 2021 | November 30, 2026 | HANLEY, DANIEL F | reporter.nih.gov |
| Interventions That Retard Mammalian Aging | NIH | National Institute on Aging | 2021 to 2025 | $8,876,368 | April 15, 2003 | May 31, 2029 | KORSTANJE, RONNY | reporter.nih.gov |
| Center for Testing Potential Anti-Aging Interventions | NIH | National Institute on Aging | 2021 to 2025 | $7,623,448 | April 15, 2004 | May 31, 2029 | SALMON, ADAM | reporter.nih.gov |
| Interventions Testing Program at UM | NIH | National Institute on Aging | 2021 to 2025 | $7,195,632 | July 1, 2003 | May 31, 2029 | MILLER, RICHARD A | reporter.nih.gov |
| Developing a NAMPT activator for Alzheimer’s disease | NIH | National Institute on Aging | 2023 to 2025 | $7,056,557 | September 15, 2023 | August 31, 2028 | CHEN, BEIBEI | reporter.nih.gov |
| Legacy Effects of CALERIE, a 2-year Calorie Restriction Intervention, on Hallmarks of Healthspan and Aging | NIH | National Institute on Aging | 2021 to 2025 | $5,317,155 | August 1, 2025 | January 31, 2027 | DAS, SAI KRUPA | reporter.nih.gov |
| Cell Type-Specific Proteins that Promote Resilience to Cognitive Aging and Alzheimer's Disease | NIH | National Institute on Aging | 2023 to 2025 | $4,581,949 | September 30, 2021 | May 31, 2027 | KACZOROWSKI, CATHERINE COOK | reporter.nih.gov |
| Mitochondrial Complex I as a Target for Neuroprotection in AD | NIH | National Institute on Aging | 2022 to 2025 | $3,730,239 | April 1, 2017 | August 31, 2027 | TRUSHINA, EUGENIA | reporter.nih.gov |
| Advancing Psychosocial and Biobehavioral Stress Measurement and Interventions to Promote Healthy Aging | NIH | National Institute on Aging | 2021 to 2025 | $3,725,466 | September 1, 2014 | May 31, 2029 | EPEL, ELISSA S. | reporter.nih.gov |
| Understanding the role of senescence on post-operative neuroinflammation | NIH | National Institute on Aging | 2022 to 2025 | $3,674,270 | September 15, 2022 | August 31, 2027 | VARGHESE, SHYNI | reporter.nih.gov |
| Cognitively engaging walking exercise and neuromodulation to enhance brain function in older adults | NIH | National Institute on Aging | 2023 to 2025 | $3,606,450 | May 1, 2023 | April 30, 2027 | CLARK, DAVID J | reporter.nih.gov |
| Molecular Mechanisms and Genetic Basis of Human Ovarian Aging | NIH | National Institute on Aging | 2025 | $3,445,585 | September 1, 2025 | August 31, 2029 | SUH, YOUSIN | reporter.nih.gov |
| Caenorhabditis Intervention Testing Program: Interventions That Modulate Health, Longevity and Aging Hallmarks | NIH | National Institute on Aging | 2021 to 2025 | $3,343,689 | August 15, 2013 | July 31, 2027 | DRISCOLL, MONICA A. | reporter.nih.gov |
| Toward development of senolytic CAR T cells | NIH | National Institute on Aging | 2025 | $3,326,400 | May 15, 2020 | August 31, 2029 | LOWE, SCOTT W. | reporter.nih.gov |
| Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers | NIH | National Institute on Aging | 2021 to 2025 | $3,134,540 | January 1, 2021 | December 31, 2026 | KRAUS, VIRGINIA B | reporter.nih.gov |
| Neural stem cell rejuvenation through single cell pharmacogenomics | NIH | National Institute on Aging | 2022 to 2025 | $3,117,021 | June 15, 2022 | February 28, 2027 | BONAGUIDI, MICHAEL | reporter.nih.gov |
| Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD Risk | NIH | National Institute on Aging | 2022 to 2025 | $3,111,864 | June 1, 2015 | May 31, 2027 | HARIRI, AHMAD R. | reporter.nih.gov |
| Development of a novel Alzheimer's disease therapeutic targeting tau | NIH | National Institute on Aging | 2021 to 2025 | $3,020,991 | September 15, 2018 | May 31, 2027 | LARSEN, GLENN | reporter.nih.gov |
| Acceleration of Circulatory and Neurological Aging due to Wildfire Exposures | NIH | National Institute on Aging | 2022 to 2025 | $3,018,937 | January 1, 2022 | December 31, 2026 | CAMPEN, MATTHEW J | reporter.nih.gov |
| Multidimensional predictive modeling to understand mechanisms of exercise response heterogeneity in older adults | NIH | National Institute on Aging | 2024 to 2025 | $3,015,209 | September 15, 2024 | August 31, 2029 | BAMMAN, MARCAS M | reporter.nih.gov |
| Reactive oxygen species as early-in-life modulators of lifespan | NIH | National Institute on Aging | 2025 | $2,991,725 | September 1, 2025 | August 31, 2029 | JAKOB, URSULA H. | reporter.nih.gov |
| Targeting cell senescence in a novel model of spontaneous disc degeneration | NIH | National Institute on Aging | 2021 to 2025 | $2,972,378 | September 1, 2021 | May 31, 2027 | RISBUD, MAKARAND V | reporter.nih.gov |
| Using nicotine to reverse age-related auditory processing deficits | NIH | National Institute on Aging | 2021 to 2025 | $2,935,681 | January 1, 2021 | December 31, 2026 | METHERATE, RAJU | reporter.nih.gov |
| Identifying therapeutic targets that confer synaptic resilience to Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $2,930,114 | September 30, 2018 | November 30, 2029 | HERSKOWITZ, JEREMY H. | reporter.nih.gov |
| Validating a 3rd-generation methylation measure of accelerated aging: DunedinPoAm4x | NIH | National Institute on Aging | 2022 to 2025 | $2,908,815 | June 1, 2022 | March 31, 2027 | MOFFITT, TERRIE E | reporter.nih.gov |
| USC-Buck Geroscience Training in the Biology of Aging | NIH | National Institute on Aging | 2021 to 2025 | $2,884,095 | May 1, 2016 | June 30, 2026 | CURRAN, SEAN P | reporter.nih.gov |
| Investigations CONNECTing Cancer and Aging (I-CONNECT) | NIH | National Cancer Institute | 2023 to 2025 | $2,795,458 | September 1, 2023 | August 31, 2030 | MANDELBLATT, JEANNE | reporter.nih.gov |
| The sexually dimorphic role of smooth muscle cell estrogen receptor alpha in vascular aging | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,780,367 | June 10, 2022 | May 31, 2027 | DUPONT, JENNIFER | reporter.nih.gov |
| The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults (BRIO) | NIH | National Institute on Aging | 2024 to 2025 | $2,764,013 | September 1, 2024 | February 28, 2030 | LEBRASSEUR, NATHAN K | reporter.nih.gov |
| Combining GHR antagonism with life extending compounds: a search for synergies | NIH | National Institute on Aging | 2021 to 2025 | $2,717,138 | September 1, 2018 | April 30, 2028 | KOPCHICK, JOHN JOSEPH | reporter.nih.gov |
| Reverse Engineering of Cell Senescence | NIH | National Institute on Aging | 2022 to 2025 | $2,651,475 | February 15, 2022 | November 30, 2026 | KIRSCHNER, MARC WALLACE | reporter.nih.gov |
| Hypothalamic Pathways of Age Related Homeostatic Dysregulation | NIH | National Institute on Aging | 2025 | $2,591,620 | September 15, 2025 | August 31, 2029 | RIERA, CELINE E. | reporter.nih.gov |
| Regeneration of the Immune System after Radiation Exposure | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,571,006 | August 18, 2022 | June 30, 2027 | GUHA, CHANDAN | reporter.nih.gov |
| Dissecting CEBPB Function with Synthetic Biology and Imaging | NIH | National Institute on Aging | 2022 to 2025 | $2,570,094 | February 1, 2022 | November 30, 2026 | LIONNET, TIMOTHEE | reporter.nih.gov |
| AMPK in the Development and resolution of Lung Fibrosis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,567,547 | January 15, 2019 | June 30, 2028 | ZMIJEWSKI, JAROSLAW WALDEMAR | reporter.nih.gov |
| Modulated release of anti-senescence drugs to stimulate aged bone repair | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $2,553,994 | June 1, 2012 | January 31, 2027 | KUHN, LIISA TIINA | reporter.nih.gov |
| Interaction of estrogen, age, and activity on musculoskeletal strength in females | NIH | National Institute on Aging | 2021 to 2025 | $2,538,049 | February 1, 2009 | June 30, 2029 | LOWE, DAWN A | reporter.nih.gov |
| Effects of NAD restoration on neurovascular coupling in community dwelling older adults | NIH | National Institute on Aging | 2022 to 2025 | $2,531,921 | August 15, 2022 | April 30, 2027 | YABLUCHANSKIY, ANDRIY | reporter.nih.gov |
| Molecular mechanisms of aging and accelerated aging in the human brain | NIH | National Institute on Aging | 2023 to 2025 | $2,525,941 | September 15, 2023 | May 31, 2028 | MAVRIKAKI, MARIA | reporter.nih.gov |
| Pro-youthful role of Gpld1 on regenerative and cognitive function in the aged brain | NIH | National Institute on Aging | 2022 to 2025 | $2,521,023 | May 15, 2022 | April 30, 2027 | VILLEDA, SAUL A | reporter.nih.gov |
| Patterns of biological, cognitive, and physical aging in cancer survivors and controls and the role of sleep health: Relevance for Alzheimer's Disease and Related Dementias | NIH | National Institute on Aging | 2023 to 2025 | $2,481,590 | June 15, 2023 | February 29, 2028 | CARROLL, JUDITH E | reporter.nih.gov |
| Determining the context specificity of metformin treatment on muscle mitochondria and healthspan | NIH | National Institute on Aging | 2022 to 2025 | $2,458,659 | April 1, 2022 | December 31, 2026 | MILLER, BENJAMIN FRANCIS | reporter.nih.gov |
| Deconstructing aging with senolytic CAR T cells | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $2,400,000 | September 15, 2022 | August 31, 2027 | AMOR VEGAS, CORINA | reporter.nih.gov |
| Neddylation and mitophagy in cardiac aging | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,381,119 | April 1, 2022 | March 31, 2027 | SUN, NUO | reporter.nih.gov |
| Systemic Cell Senescence as a Mediator of Brain Aging Through Circulation | NIH | National Institute on Aging | 2021 to 2025 | $2,373,349 | May 1, 2021 | July 31, 2026 | SCHAFER, MARISSA JOY | reporter.nih.gov |
| Brain-muscle microphysiological system enabled extracellular vesicle network for understanding aging in space | NIH | National Center for Advancing Translational Sciences | 2025 | $2,344,810 | August 1, 2025 | July 31, 2027 | HE, MEI | reporter.nih.gov |
| PKG Regulation of Sirtuin 1 as a Novel Treatment Strategy for Age-related Osteoporosis | NIH | National Institute on Aging | 2021 to 2025 | $2,324,065 | September 5, 2021 | May 31, 2027 | PILZ, RENATE B | reporter.nih.gov |
| Neural Stem Cell-derived EVs for Improving Aged Brain Function | NIH | National Institute on Aging | 2022 to 2025 | $2,306,114 | August 1, 2022 | April 30, 2027 | SHETTY, ASHOK K | reporter.nih.gov |
| Circadian-Regulated Aging Physiologies | NIH | National Institute on Aging | 2021 to 2025 | $2,300,834 | August 1, 2013 | April 30, 2027 | SHIRASU-HIZA, MICHELE M | reporter.nih.gov |
| The impact of insulin sensitivity on the potential of metformin to delay age-related inflammation | NIH | National Institute on Aging | 2022 to 2025 | $2,299,749 | August 15, 2022 | April 30, 2027 | NIKOLAJCZYK, BARBARA | reporter.nih.gov |
| RESTOR [Rapamycin and Everolimus Study Towards Older Rejuvenation]: An exploratory PK/PD study of mTOR inhibition in older human subjects | NIH | National Institute on Aging | 2024 to 2025 | $2,296,638 | August 15, 2024 | July 31, 2029 | KRAIG, ELLEN | reporter.nih.gov |
| Physical resilience is a predictor of healthy aging | NIH | National Institute on Aging | 2021 to 2025 | $2,295,885 | September 15, 2017 | April 30, 2028 | LADIGES, WARREN C | reporter.nih.gov |
| Methods to Test Biomarkers of Aging as Shared Determinants of Alzheimers Disease and Related Dementias and Physical Disability | NIH | National Institute on Aging | 2023 to 2025 | $2,280,060 | February 1, 2023 | November 30, 2028 | SHARDELL, MICHELLE DENISE | reporter.nih.gov |
| Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions | NIH | National Institute on Aging | 2021 to 2025 | $2,263,786 | May 1, 2021 | February 28, 2027 | ADAMS, PETER D. | reporter.nih.gov |
| SIRT6 and vascular endothelial homeostasis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,246,157 | July 1, 2017 | June 30, 2026 | JIN, ZHENG-GEN | reporter.nih.gov |
| Proactive pharyngeal swallowing exercises: Building muscular reserve in pre-frail older adults | NIH | National Institute on Aging | 2025 | $2,242,633 | September 15, 2023 | August 31, 2028 | MOLFENTER, SONJA M | reporter.nih.gov |
| Role of Chaperone GRP78 and Mitochondrial Dysfunction in ER Stress-Mediated Pulmonary Fibrosis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,221,038 | August 1, 2013 | December 31, 2026 | ZHOU, BEIYUN | reporter.nih.gov |
| Heterozygous SERPINE1 Deficiency Confers Durable Cardiovascular Fitness in Humans | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,212,020 | January 1, 2024 | December 31, 2030 | VAUGHAN, DOUGLAS E | reporter.nih.gov |
| Dysregulated Immunometabolism and Premature Senescence in Corticosteroid-Refractory Severe Asthma | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,209,066 | February 1, 2023 | January 31, 2030 | RAY, ANURADHA | reporter.nih.gov |
| Strengthening gut barrier integrity with beneficial microbes to increase lifespan and healthspan | NIH | National Institute on Aging | 2022 to 2025 | $2,197,864 | September 15, 2021 | May 31, 2027 | CROTT, JIMMY W | reporter.nih.gov |
| Promoting regenerative repair of aged cartilage | NIH | National Institute on Aging | 2023 to 2025 | $2,189,662 | May 15, 2023 | January 31, 2028 | COLLINS, JOHN A | reporter.nih.gov |
| Epicardial remodeling in cardiomyopathy and cardiac aging | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,189,655 | April 1, 2011 | February 28, 2029 | XU, XIAOLEI | reporter.nih.gov |
| Systemic Mechanisms of Brain Rejuvenation | NIH | National Institute on Aging | 2022 to 2025 | $2,186,183 | June 15, 2022 | February 28, 2027 | VILLEDA, SAUL A | reporter.nih.gov |
| The role of the senescent microenvironment on cancer initiating cells in the colon. | NIH | National Institute on Aging | 2021 to 2025 | $2,183,637 | September 30, 2021 | August 31, 2026 | GRADY, WILLIAM MALLORY | reporter.nih.gov |
| Metabolic Interventions for Sleep, Anesthesia-related Neurocognitive Disorders and Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $2,137,648 | June 15, 2022 | February 28, 2027 | NEHS, CHRISTA JOY | reporter.nih.gov |
| Mechanisms of marrow microenvironmental aging and their impact of progression of clonal hematopoiesis | NIH | National Institute on Aging | 2022 to 2025 | $2,128,718 | July 15, 2022 | March 31, 2027 | CALVI, LAURA M | reporter.nih.gov |
| Re-entry Supplement associated with R01AG08073 | NIH | National Institute on Aging | 2023 to 2025 | $2,121,347 | August 1, 2023 | April 30, 2028 | DRAKE, JOSH C | reporter.nih.gov |
| Novel longevity enhancing pathways regulated by mTOR | NIH | National Institute on Aging | 2022 to 2025 | $2,120,259 | July 1, 2022 | March 31, 2027 | SELL, CHRISTIAN | reporter.nih.gov |
| Role of Mitochondrial Homeostasis in Animal Aging | NIH | National Institute on Aging | 2021 to 2025 | $2,106,772 | July 1, 2010 | July 31, 2025 | WALKER, DAVID W | reporter.nih.gov |
| Temporal control of mitochondrial mutagenesis | NIH | National Institute on Aging | 2022 to 2025 | $2,066,347 | September 30, 2022 | June 30, 2027 | VERMULST, MARC | reporter.nih.gov |
| The Role of Adenine Nucleotide Translocase in Mitochondrial Dysfunction Associated Senescence in Chronic Obstructive Pulmonary Disease (COPD) | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,059,255 | August 1, 2023 | April 30, 2028 | KLIMENT, CORRINE R | reporter.nih.gov |
| Advanced Pre-clinical development of Nox4 inhibitors for Pulmonary Fibrosis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,045,720 | June 1, 2024 | May 31, 2027 | PATTI, JOSEPH | reporter.nih.gov |
| Single nuclei RNA-sequencing to map adipose cellular populations and senescent cells in older subjects | NIH | National Institute on Aging | 2023 to 2025 | $2,040,398 | June 15, 2022 | February 28, 2027 | MUSI, NICOLAS | reporter.nih.gov |
| TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | NIH | National Institute on Aging | 2025 | $2,039,697 | September 1, 2023 | August 31, 2028 | NEWMAN, JOHN C | reporter.nih.gov |
| Insulin-Like Growth Factor-1 and Atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,035,860 | December 5, 2002 | June 30, 2027 | DELAFONTAINE, PATRICE | reporter.nih.gov |
| Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline | NIH | National Cancer Institute | 2023 to 2025 | $2,026,604 | September 1, 2023 | August 31, 2028 | SEDRAK, MINA S | reporter.nih.gov |
| Multidimensional aging trajectories in mid to late-life psychosis (MAP) | NIH | National Institute of Mental Health | 2024 to 2025 | $2,026,181 | December 15, 2023 | October 31, 2028 | LEE, JUNGHEE | reporter.nih.gov |
| Test of Rapamycin in Aging Dogs (TRIAD) | NIH | National Institute on Aging | 2025 | $2,015,762 | December 1, 2024 | November 30, 2029 | CREEVY, KATE ELIZABETH | reporter.nih.gov |
| Sphingolipid signaling in age-associated vascular pathology | NIH | National Institute on Aging | 2022 to 2025 | $2,011,994 | September 1, 2022 | May 31, 2027 | HLA, TIMOTHY TUN | reporter.nih.gov |
| Novel Inhibitors of Lysine Methyltransferases G9a and GLP for the Treatment of Alzheimer's Disease | NIH | National Institute on Aging | 2023 to 2025 | $1,983,203 | September 15, 2023 | June 30, 2028 | JIN, JIAN | reporter.nih.gov |
| The Role of Cellular Senescence in Carpal Tunnel Syndrome | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,971,867 | September 10, 2020 | November 30, 2026 | GINGERY, ANNE | reporter.nih.gov |
| The influence of proteostasis loss in aging hematopoietic stem cells on leukemia initiation | NIH | National Cancer Institute | 2021 to 2025 | $1,966,052 | September 15, 2021 | August 31, 2026 | SIGNER, ROBERT A.J. | reporter.nih.gov |
| MASS: Muscle and disease in postmenopausal women | NIH | National Institute on Aging | 2023 to 2025 | $1,961,423 | September 1, 2023 | May 31, 2028 | WACTAWSKI-WENDE, JEAN | reporter.nih.gov |
| GEROSCIENCE TRAINING PROGRAM IN OKLAHOMA | NIH | National Institute on Aging | 2021 to 2025 | $1,960,091 | May 1, 2017 | April 30, 2027 | SONNTAG, WILLIAM EDMUND | reporter.nih.gov |
| Genetic Basis of Lifespan and Healthspan Extension by ACE Inhibition in Drosophila | NIH | National Institute on Aging | 2022 to 2025 | $1,943,842 | August 15, 2022 | April 30, 2027 | MACKAY, TRUDY F. | reporter.nih.gov |
| Role of DNA damage and cellular senescence in osteoarthritis pathophysiology | NIH | National Institute on Aging | 2023 to 2025 | $1,923,686 | September 30, 2023 | May 31, 2028 | DIEKMAN, BRIAN O | reporter.nih.gov |
| Different consequences of cellular aging in cortical versus cancellous bone- Resubmission | NIH | National Institute on Aging | 2021 to 2025 | $1,910,179 | April 1, 2021 | December 31, 2026 | ALMEIDA, MARIA JOSE | reporter.nih.gov |
| Exercise-Associated Signaling Against CNS Aging and Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $1,908,200 | September 30, 2022 | May 31, 2027 | CORTES, CONSTANZA JAVIERA | reporter.nih.gov |
| Preserving bone marrow niche integrity and function to rejuvenate aged hematopoietic stem cells | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,907,139 | July 1, 2023 | May 31, 2027 | BUTLER, JASON MATHEW | reporter.nih.gov |
| Cellular and Tissue Rejuvenation through Transcriptional Reprogramming | NIH | National Institute on Aging | 2023 to 2025 | $1,889,504 | August 1, 2023 | April 30, 2028 | LI, HAO | reporter.nih.gov |
| Improving Aged Neuromuscular Health and Function | NIH | National Institute on Aging | 2022 to 2025 | $1,878,947 | June 1, 2022 | March 31, 2027 | LAVASANI, MITRA | reporter.nih.gov |
| Modulation of aging through mechanisms of nutrient demand and reward | NIH | National Institute on Aging | 2021 to 2025 | $1,877,928 | September 1, 2021 | May 31, 2026 | PLETCHER, SCOTT | reporter.nih.gov |
| Aging-associated mammary cancer-initiating cells | NIH | National Cancer Institute | 2021 to 2025 | $1,860,500 | September 17, 2021 | August 31, 2026 | SUN, LUZHE | reporter.nih.gov |
| The regulation of cancer and aging by methionine | NIH | National Institute on Aging | 2023 to 2025 | $1,852,002 | July 1, 2023 | March 31, 2028 | LAMMING, DUDLEY WILLIAM | reporter.nih.gov |
| Regulation of Alveolar Bone Marrow MSC Senescence in Skeletal Aging and Periodontitis | NIH | National Institute of Dental & Craniofacial Research | 2021 to 2025 | $1,841,385 | July 2, 2021 | April 30, 2027 | KIM, REUBEN HAN-KYU | reporter.nih.gov |
| Roles of aging and cellular senescence in the development of intracranial aneurysm rupture | NIH | National Institute on Aging | 2023 to 2025 | $1,814,797 | June 1, 2023 | February 29, 2028 | HASHIMOTO, TOMOKI | reporter.nih.gov |
| Senescence-on-a-chip: Building a microphysiological 3D skin model | NIH | National Cancer Institute | 2024 to 2025 | $1,809,500 | August 5, 2022 | July 31, 2026 | CHRISTIANO, ANGELA M | reporter.nih.gov |
| Mediators of Muscle Rejuvenation with Aging | NIH | National Institute on Aging | 2023 to 2025 | $1,776,810 | August 1, 2023 | April 30, 2028 | MURACH, KEVIN | reporter.nih.gov |
| Heme-mediated Mitochondrial Injury, Senescence, Acute Kidney Injury and Chronic Kidney Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,773,553 | March 15, 2023 | January 31, 2027 | NATH, KARL A. | reporter.nih.gov |
| Extracellular vesicle-based senotherapeutics for aging diabetic kidneydisease | NIH | National Institute on Aging | 2023 to 2025 | $1,725,246 | June 1, 2023 | February 29, 2028 | HICKSON, LATONYA J | reporter.nih.gov |
| Genetic and Molecular Basis of Longevity | NIH | National Institute on Aging | 2022 to 2025 | $1,719,200 | April 1, 1999 | May 31, 2027 | RUVKUN, GARY B | reporter.nih.gov |
| Pitt Integrated Clinical and Geroscience Research Training Program | NIH | National Institute on Aging | 2021 to 2025 | $1,718,608 | May 1, 2003 | April 30, 2029 | FORMAN, DANIEL E. | reporter.nih.gov |
| Understanding the role of the cerebral microvasculature in brain aging | NIH | National Institute on Aging | 2023 to 2025 | $1,718,194 | August 1, 2023 | April 30, 2028 | RUTKAI-GREEN, IBOLYA | reporter.nih.gov |
| The Hypothalamic Basis of Aging | NIH | National Institute on Aging | 2023 to 2025 | $1,712,310 | February 1, 2010 | May 31, 2028 | CAI, DONGSHENG | reporter.nih.gov |
| The Impact of Aging on Prostate Cancer with Age-Related Disruption of Th17/Treg Axis | NIH | National Cancer Institute | 2021 to 2025 | $1,707,208 | January 1, 2021 | December 31, 2026 | ZHANG, QIUYANG | reporter.nih.gov |
| Role of Macrophage in Osteoimmunology with Aging | NIH | National Institute on Aging | 2022 to 2025 | $1,705,474 | May 1, 2022 | January 31, 2027 | YAO, ZHENQIANG | reporter.nih.gov |
| Anti-Aging Molecule Sirt6 in Neuroprotection in Diabetic Retina | NIH | National Eye Institute | 2023 to 2025 | $1,699,769 | May 1, 2023 | April 30, 2028 | ZHANG, WENBO | reporter.nih.gov |
| Mitochondrial DNA Deletion Mutation Frequency as a Metric of Biologic Age | NIH | National Institute on Aging | 2022 to 2025 | $1,687,306 | May 15, 2022 | January 31, 2027 | WANAGAT, JONATHAN | reporter.nih.gov |
| Deciphering age-dependent beige adipocyte failure | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,682,779 | March 15, 2022 | January 31, 2027 | BERRY, DANIEL CARL | reporter.nih.gov |
| International Registry for Werner Syndrome | NIH | National Cancer Institute | 2021 to 2025 | $1,678,533 | February 4, 2022 | January 31, 2027 | OSHIMA, JUNKO | reporter.nih.gov |
| Nucleus-to-cytoplasm trafficking of chromatin fragments in senescence and aging | NIH | National Institute on Aging | 2023 to 2025 | $1,656,739 | September 1, 2023 | May 31, 2028 | DOU, ZHIXUN | reporter.nih.gov |
| Small molecule approach to activate human SIRT5 | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,654,885 | May 1, 2022 | January 31, 2027 | CEN, YANA | reporter.nih.gov |
| Elucidating and targeting beta-cell senescence and its SASP | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,649,136 | May 10, 2022 | April 30, 2027 | AGUAYO-MAZZUCATO, CRISTINA | reporter.nih.gov |
| Discovering how autophagy is sufficient to extend yeast replicative lifespan (SUPPLEMENT) | NIH | National Institute on Aging | 2023 to 2025 | $1,648,869 | September 1, 2023 | April 30, 2028 | TYLER, JESSICA K | reporter.nih.gov |
| Identification and Characterization of Senescent Cells in Molecular Subtypes of Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $1,648,493 | September 15, 2024 | June 30, 2029 | ZHANG, BIN | reporter.nih.gov |
| MOTS-C, APOE, and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $1,637,287 | August 15, 2024 | July 31, 2029 | PIKE, CHRISTIAN J | reporter.nih.gov |
| CHCHD10 Frontotemporal Dementia, Molecular Mechanisms and Therapeutic Strategies | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,635,738 | August 22, 2024 | July 31, 2029 | FUJITA, HIBIKI | reporter.nih.gov |
| Chemotherapy-induced vascular cognitive impairment: role of endothelial senescence | NIH | National Cancer Institute | 2021 to 2025 | $1,628,588 | January 1, 2021 | December 31, 2026 | CSISZAR, ANNA | reporter.nih.gov |
| Targeting Biology of Aging Mechanisms Underlying Alzheimer's Disease Risk with Metformin | NIH | National Institute on Aging | 2024 to 2025 | $1,625,983 | September 30, 2024 | June 30, 2029 | ESPINOZA, SARA ELYSE | reporter.nih.gov |
| Oxidative Stress and the Development of Osteoarthritis | NIH | National Institute on Aging | 2021 to 2025 | $1,625,347 | September 30, 2012 | February 29, 2028 | LOESER, RICHARD F | reporter.nih.gov |
| mitoNEET as a therapeutic target for mitigating ischemic brain injury following MCAO | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,605,405 | September 1, 2023 | July 31, 2028 | HUBER, JASON D | reporter.nih.gov |
| Brain Aging Across the Lifespan in Neurodevelopmental Disorders | NIH | National Institute of Mental Health | 2024 to 2025 | $1,599,372 | November 20, 2023 | October 31, 2028 | SCHUMANN, CYNTHIA | reporter.nih.gov |
| Role of transposon regulation in the negligible senescence of S. mediterranea | NIH | National Institute on Aging | 2022 to 2025 | $1,598,038 | July 15, 2022 | March 31, 2027 | VAN WOLFSWINKEL, JOSEPHINA C | reporter.nih.gov |
| Stem Cell-Derived Exosomes, MrgD and Vascular Cognitive Impairment in Aging | NIH | National Institute on Aging | 2021 to 2025 | $1,582,923 | September 15, 2017 | April 30, 2028 | JARAJAPU, YAGNA | reporter.nih.gov |
| Investigating the role of Lef1 in fibroblast lineages to induce skin regeneration and reverse aging | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2021 to 2025 | $1,576,466 | May 7, 2021 | April 30, 2027 | DRISKELL, RYAN | reporter.nih.gov |
| Harnessing CAR T cells to deconstruct the interconnectivity among hallmarks of aging | NIH | National Institute on Aging | 2023 to 2025 | $1,574,107 | September 15, 2023 | May 31, 2028 | AMOR VEGAS, CORINA | reporter.nih.gov |
| Modifying the extracellular matrix to prevent dry eye disease and age-related Meibomian gland dysfunction (ARMGD) | NIH | National Eye Institute | 2022 to 2025 | $1,564,364 | May 1, 2022 | April 30, 2027 | COULSON-THOMAS, VIVIEN JANE | reporter.nih.gov |
| Molecular Assessment of Cause and Consequence of Cellular Senescence in Diverse Midbrain Cell Types in Parkinson's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,562,350 | July 15, 2022 | June 30, 2027 | RIESSLAND, MARKUS | reporter.nih.gov |
| Investigating the role of cytosolic mitochondrial double-stranded RNA in cellular senescence and aging | NIH | National Institute on Aging | 2023 to 2025 | $1,535,283 | September 15, 2023 | May 31, 2029 | PASSOS, JOAO | reporter.nih.gov |
| Mechanisms of Cellular Senescence Driving Intervertebral Disc Aging through Local Cell Autonomous and Systemic Non-Cell Autonomous Processes | NIH | National Institute on Aging | 2023 to 2025 | $1,506,076 | May 15, 2023 | January 31, 2028 | VO, NAM V | reporter.nih.gov |
| Protective effects of metformin against cigarette smoke-induced lung pathologies via regulation of fatty acids metabolism | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,492,860 | August 1, 2024 | July 31, 2028 | POLVERINO, FRANCESCA | reporter.nih.gov |
| The role of diet and aging in photoreceptor homeostasis and visual function decline | NIH | National Institute on Aging | 2024 to 2025 | $1,475,927 | July 1, 2024 | May 31, 2029 | KAPAHI, PANKAJ | reporter.nih.gov |
| CNS Senescence and Immunopathology in Lethal POWV Infection of Aged Mice | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,444,052 | August 16, 2024 | July 31, 2029 | MACKOW, ERICH R | reporter.nih.gov |
| A New Translational Rat Model for Evaluating Anti-Aging Interventions | NIH | National Institute on Aging | 2024 to 2025 | $1,442,827 | July 15, 2022 | June 30, 2027 | RICHARDSON, ARLAN G. | reporter.nih.gov |
| Exploring novel therapeutic strategies for combinatory therapy to treat renal clear cell carcinomas | NIH | National Cancer Institute | 2023 to 2025 | $1,428,783 | January 1, 2023 | December 31, 2027 | ZHANG, WEIZHOU | reporter.nih.gov |
| Cognitive SuperAging: A model to explore resilience and resistance to aging and Alzheimers disease | NIH | National Institute on Aging | 2023 to 2025 | $1,421,674 | September 1, 2023 | November 30, 2026 | ROGALSKI, EMILY J | reporter.nih.gov |
| Ifi27l2a as a therapeutic target for stroke | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,406,237 | July 15, 2023 | April 30, 2028 | KIM, GAB SEOK | reporter.nih.gov |
| Discovery and manipulation of transcription factors to restore long term stem cell repopulation in aged bone-marrow | NIH | National Institute on Aging | 2024 to 2025 | $1,399,932 | August 4, 2022 | April 30, 2027 | ABUDAYYEH, OMAR O | reporter.nih.gov |
| Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,364,501 | March 1, 2024 | February 28, 2029 | VERDIN, ERIC M. | reporter.nih.gov |
| Interorgan communication in aging in Drosophila | NIH | National Institute on Aging | 2024 to 2025 | $1,317,801 | May 15, 2024 | January 31, 2029 | PERRIMON, NORBERT | reporter.nih.gov |
| Tissue senescence and age-associated metabolic dysfunction: the role of immune cell mediated inflammation | NIH | National Institute on Aging | 2023 to 2025 | $1,315,608 | March 15, 2023 | December 31, 2027 | LESNIEWSKI, LISA A | reporter.nih.gov |
| Circadian Rhythm and Lifespan | NIH | National Institute on Aging | 2024 to 2025 | $1,311,903 | May 1, 2024 | April 30, 2029 | TAKAHASHI, JOSEPH S | reporter.nih.gov |
| Mechanisms of HIV-associated Hypertension | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,311,860 | September 1, 2024 | August 31, 2028 | BELIN DE CHANTEMELE, ERIC J | reporter.nih.gov |
| Methionine Cycle as a Mechanistic Hub for the Hallmarks of Aging | NIH | National Institute on Aging | 2023 to 2025 | $1,309,806 | September 15, 2023 | May 31, 2028 | TATAR, MARC | reporter.nih.gov |
| Senescence in the Foreign Body Response Across Lifespan | NIH | National Institute on Aging | 2024 to 2025 | $1,307,810 | April 1, 2024 | January 31, 2029 | ELISSEEFF, JENNIFER H | reporter.nih.gov |
| Role of Mitochondrial Quality Control in Bone Homeostasis and Disease | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2022 to 2025 | $1,302,642 | August 1, 2022 | July 31, 2027 | KIM, HA-NEUI | reporter.nih.gov |
| A novel cilium-to-nucleus axis promotes cellular senescence | NIH | National Institute on Aging | 2022 to 2025 | $1,297,281 | June 1, 2022 | February 28, 2027 | HU, JINGHUA | reporter.nih.gov |
| Translation Fidelity in Hematopoietic Stem Cell Aging and Longevity | NIH | National Institute on Aging | 2024 to 2025 | $1,285,348 | July 15, 2024 | June 30, 2029 | SIGNER, ROBERT A.J. | reporter.nih.gov |
| Mechanisms underlying reversal of cardiac aging by urolithin a treatment | NIH | National Institute on Aging | 2024 to 2025 | $1,282,390 | September 15, 2024 | August 31, 2029 | MARCINEK, DAVID J. | reporter.nih.gov |
| Small molecule mimetics of Humanin that normalize neuronal p-Akt as novel therapeutics for AD | NIH | National Institute on Aging | 2024 to 2025 | $1,277,110 | April 1, 2021 | March 31, 2027 | JOHN, VARGHESE | reporter.nih.gov |
| Translational analysis of a novel intervention to promote healthy aging. | NIH | National Institute on Aging | 2024 to 2025 | $1,276,340 | September 1, 2024 | August 31, 2029 | COLMAN, RICKI J | reporter.nih.gov |
| Leveraging senotherapeutic properties of metformin to improve collagen remodeling during muscle regrowth in older adults | NIH | National Institute on Aging | 2024 to 2025 | $1,245,299 | June 1, 2024 | May 31, 2029 | DRUMMOND, MICAH J | reporter.nih.gov |
| Impact of Senolytics on Aged Vaccine Responses | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,244,166 | November 1, 2022 | October 31, 2027 | BARTLEY, JENNA | reporter.nih.gov |
| Impacting Inflammation through Mechanistic Target of Rapamycin (imTOR) | NIH | National Institute on Aging | 2024 to 2025 | $1,243,859 | September 1, 2024 | May 31, 2028 | NIKOLAJCZYK, BARBARA | reporter.nih.gov |
| Preventive mechanisms of Age-associated Thrombosis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,240,850 | January 1, 2024 | December 31, 2027 | DAYAL, SANJANA | reporter.nih.gov |
| Metabolic deficits and immune dysfunction in aging people living with HIV | NIH | National Institute on Aging | 2024 to 2025 | $1,226,631 | July 1, 2024 | June 30, 2029 | FRASCA, DANIELA | reporter.nih.gov |
| Pharmacokinetics (PK) and Pharmacodynamics (PD) Characterization of mTOR Inhibitors in Older Adults | NIH | National Institute on Aging | 2024 to 2025 | $1,225,917 | September 1, 2024 | August 31, 2027 | TIMOFTE, IRINA | reporter.nih.gov |
| Impact of mammalian target of rapamycin inhibitor therapy on aging-related outcomes | NIH | National Institute on Aging | 2023 to 2025 | $1,223,110 | February 1, 2023 | November 30, 2027 | BITTERMANN, THERESE | reporter.nih.gov |
| Metabolomics clocks as a tool to explore mechanisms of aging | NIH | National Institute on Aging | 2024 to 2025 | $1,219,973 | September 30, 2024 | June 30, 2029 | PROMISLOW, DANIEL EDWARD | reporter.nih.gov |
| Regulation of kidney function and blood pressure in aging | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,214,215 | April 1, 2024 | March 31, 2028 | SUN, ZHONGJIE | reporter.nih.gov |
| SGLT2 inhibition as a therapeutic strategy to reverse arterial stiffening in aging | NIH | National Institute on Aging | 2024 to 2025 | $1,209,167 | June 1, 2024 | February 28, 2029 | MANRIQUE ACEVEDO, CAMILA MARGARITA | reporter.nih.gov |
| Role of p21 positive senescent cells in radiation-induced skeletal injury and repair | NIH | National Institute on Aging | 2023 to 2025 | $1,202,430 | August 1, 2023 | April 30, 2028 | CHANDRA, ABHISHEK | reporter.nih.gov |
| Using microgravity to model inflammaging in complex organ chip models of heart, gut, and brain | NIH | National Institute on Aging | 2025 | $1,202,427 | August 15, 2025 | July 31, 2028 | SHARMA, ARUN | reporter.nih.gov |
| Network on Biomarker Collection and Measurement in Population Studies of Aging: 2022-2027 | NIH | National Institute on Aging | 2022 to 2025 | $1,188,887 | September 15, 2016 | March 31, 2028 | FAUL, JESSICA | reporter.nih.gov |
| Regulatory Mechanisms Governing BubR1 Protein Stability During Stress and Aging | NIH | National Institute on Aging | 2022 to 2025 | $1,187,135 | June 1, 2022 | March 31, 2027 | NORTH, BRIAN J. | reporter.nih.gov |
| Targeting Senescence Specific Mechanisms of NF-κB Activation to Reverse Chronic Pulmonary Fibrosis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,178,040 | May 1, 2024 | February 28, 2029 | HAAK, ANDREW JON | reporter.nih.gov |
| Nutrient signaling at ER-Mitochondrial contacts and age-related mitochondrial dysfunction | NIH | National Institute on Aging | 2023 to 2025 | $1,171,916 | August 1, 2023 | April 30, 2028 | SINGH, RAJAT | reporter.nih.gov |
| Cerebral microhemorrhages and gait abnormalities in aging | NIH | National Institute on Aging | 2021 to 2025 | $1,154,620 | September 15, 2024 | June 30, 2030 | CSISZAR, ANNA | reporter.nih.gov |
| Mitochondrial Malfunction in T Cell Aging and Tissue Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,144,649 | March 1, 2024 | February 28, 2029 | WEYAND, CORNELIA M. | reporter.nih.gov |
| Extratumoral biological determinants that decrease survival in older adults with glioblastoma | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,143,450 | August 19, 2023 | April 30, 2028 | WAINWRIGHT, DEREK ALAN | reporter.nih.gov |
| Progressive states of cell-cycle withdrawal | NIH | National Institute on Aging | 2023 to 2025 | $1,115,089 | September 30, 2023 | May 31, 2028 | SPENCER, SABRINA LEIGH | reporter.nih.gov |
| Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut Microbiome | NIH | National Institute on Aging | 2024 to 2025 | $1,109,703 | September 1, 2024 | April 30, 2030 | LILA, MARY ANN ANN | reporter.nih.gov |
| Cell senescence in aging fracture | NIH | National Institute on Aging | 2024 to 2025 | $1,090,936 | July 15, 2024 | June 30, 2029 | ZHANG, HENGWEI | reporter.nih.gov |
| Mechanosensing in lung fibrosis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,074,798 | July 15, 2024 | June 30, 2028 | GARCIA, ANDRES J | reporter.nih.gov |
| An Organ-on-Chip Approach to Evaluation of Reproductive Health, Aging and Disease inWomen | NIH | National Center for Advancing Translational Sciences | 2025 | $1,048,481 | August 15, 2025 | July 31, 2028 | GERMAN, CARRIE | reporter.nih.gov |
| Characterization of senescent cell populations in skeletal aging | NIH | National Institute on Aging | 2024 to 2025 | $1,031,246 | August 1, 2024 | April 30, 2029 | KHOSLA, SUNDEEP | reporter.nih.gov |
| Organ system cross talk in ischemic heart disease | NIH | National Institute on Aging | 2024 to 2025 | $985,992 | September 1, 2024 | May 31, 2029 | NGUYEN, PATRICIA KIM PHUONG | reporter.nih.gov |
| Telomere uncapping epigenetically reprograms a stress response and longevity pathway | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $974,002 | March 15, 2024 | February 28, 2029 | AHMED, SHAWN CAMERON | reporter.nih.gov |
| Repurposing drugs for Alzheimer´s disease using a reverse translational approach | NIH | National Institute on Aging | 2024 to 2025 | $973,150 | August 15, 2021 | July 31, 2026 | HAGG, SARA | reporter.nih.gov |
| Neuroinflammatory GeroMiRs and Alcohol: Defining Mechanisms of ADRD | NIH | National Institute on Alcohol Abuse and Alcoholism | 2024 to 2025 | $969,398 | April 1, 2024 | March 31, 2029 | SMATHERS MCCULLOUGH, REBECCA LEANNE | reporter.nih.gov |
| Aging and Stem Cell Resilience | NIH | National Institute on Aging | 2024 to 2025 | $962,224 | April 1, 2021 | December 31, 2026 | RANDO, THOMAS A. | reporter.nih.gov |
| A Meal Delivery and Exercise Intervention to Increase Resilience in Homebound Older Adults | NIH | National Institute on Aging | 2021 to 2025 | $955,395 | May 1, 2021 | February 28, 2027 | LEE, JESSICA LAN | reporter.nih.gov |
| Inflammaging and Diabetic Retinopathy | NIH | National Eye Institute | 2024 to 2025 | $939,708 | September 1, 2024 | June 30, 2028 | BARTOLI, MANUELA | reporter.nih.gov |
| Targeting the longevity regulator PAPP-A with small molecule inhibitors | NIH | National Institute on Aging | 2024 to 2025 | $936,571 | August 1, 2022 | June 30, 2027 | NIKOLOVSKA-COLESKA, ZANETA | reporter.nih.gov |
| AI-driven Drug Discovery Targeting Cardiac Fibrosis in Aging Heart | NIH | National Institute on Aging | 2025 | $900,195 | September 1, 2025 | August 31, 2027 | WU, JOSEPH C. | reporter.nih.gov |
| Cerebromicrovascular rejuvenation by heterochronic blood exchange | NIH | National Institute on Aging | 2024 to 2025 | $875,461 | June 1, 2021 | May 31, 2027 | UNGVARI, ZOLTAN ISTVAN | reporter.nih.gov |
| Epigenetic Modulation of Cellular Senescence in the Cystic Fibrosis Lung | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $869,259 | April 1, 2024 | February 29, 2028 | SANDERS, YAN | reporter.nih.gov |
| Theranostic CAR-T Targeting Senescence in Alzheimer's | NIH | National Institute on Aging | 2025 | $834,627 | March 19, 2025 | February 28, 2027 | CUI, LINA | reporter.nih.gov |
| Translational Geroscience Network | NIH | National Institute on Aging | 2025 | $795,615 | February 1, 2019 | June 30, 2029 | KIRKLAND, JAMES L. | reporter.nih.gov |
| Pathogen-induced cellular senescence and blood-brain barrier dysfunction in Alzheimer's Disease | NIH | National Institute on Aging | 2025 | $794,341 | January 1, 2025 | December 31, 2029 | REHMAN, JALEES | reporter.nih.gov |
| Develop and validate demineralized bone paper-based human bone metabolic and senolytic assays | NIH | National Cancer Institute | 2024 to 2025 | $790,767 | August 1, 2024 | July 31, 2027 | LEE, JUNGWOO | reporter.nih.gov |
| Academic Leadership Award - The Translational Rehabilitation in Geroscience Initiative | NIH | National Institute on Aging | 2021 to 2025 | $790,466 | April 1, 2021 | June 30, 2026 | THOMPSON, LADORA V | reporter.nih.gov |
| Dissecting the cellular and spatial tissue clock of the human lung and peripheral blood | NIH | National Institute on Aging | 2025 | $789,664 | May 15, 2025 | March 31, 2030 | TSANKOV, ALEXANDER MINCHEV | reporter.nih.gov |
| Undergraduate Fundamentals in Aging Research | NIH | National Institute on Aging | 2023 to 2025 | $789,421 | August 15, 2023 | April 30, 2027 | CAMPELLONE, KENNETH G | reporter.nih.gov |
| Targeting P21 positive senescent cells for alleviating TMJ degeneration | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $784,359 | September 5, 2024 | June 30, 2029 | YADAV, SUMIT | reporter.nih.gov |
| Endothelial cell senescence and APOE4 in vascular cognitive impairment and dementia | NIH | National Institute on Aging | 2024 to 2025 | $774,675 | March 15, 2021 | February 28, 2026 | KANEKIYO, TAKAHISA | reporter.nih.gov |
| Role of Intestinal Homeostasis in Organismal Aging | NIH | National Institute on Aging | 2024 to 2025 | $772,200 | August 1, 2015 | April 30, 2027 | WALKER, DAVID W | reporter.nih.gov |
| Enhancing Cognitive Resilience In Parkinson's Disease: Role Of Antiaging Protein Klotho | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $760,801 | September 1, 2022 | August 31, 2027 | LUTHRA, NIJEE | reporter.nih.gov |
| Targeting Ceramide Signaling: Enhancing Healthy Aging and Combating Tauopathy in Mammals | NIH | National Institute on Aging | 2025 | $753,728 | December 1, 2024 | November 30, 2029 | SUN, LIOU Y. | reporter.nih.gov |
| p16 Cellular Senescence and Vascular Dysfunction in Sleep Apnea | NIH | National Heart, Lung, and Blood Institute | 2025 | $749,508 | April 15, 2025 | April 30, 2028 | CORTESE, RENE GABRIEL | reporter.nih.gov |
| Impact of a Novel Secreted Enzyme J18 on Healthspan and Lifespan | NIH | National Institute on Aging | 2023 to 2025 | $742,020 | August 15, 2021 | March 31, 2027 | ZHAO, SHANGANG | reporter.nih.gov |
| Role of Adiponectin in Reversal of Age-related Vascular Dysfunction | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $721,542 | February 15, 2023 | November 30, 2026 | DELP, JUDY M | reporter.nih.gov |
| Effect of Aging on Preadipocyte Differentiation | NIH | National Institute on Aging | 2025 | $708,285 | May 15, 1997 | March 31, 2027 | KIRKLAND, JAMES L. | reporter.nih.gov |
| The Role of SALTe1 in Vascular Aging and Heart Failure With Preserved Ejection Fraction | NIH | National Heart, Lung, and Blood Institute | 2025 | $708,266 | January 1, 2025 | December 31, 2028 | LI, HAOBO | reporter.nih.gov |
| Connecting surgical stress to sex-dependent vulnerabilities in aging and aging hallmarks | NIH | National Institute on Aging | 2025 | $699,344 | September 1, 2025 | August 31, 2027 | HUFFMAN, DEREK MAJOR | reporter.nih.gov |
| Exogenous ketones target geroscience pathways and ameliorate geriatric syndromes | NIH | National Institute on Aging | 2022 to 2025 | $698,763 | September 15, 2022 | June 30, 2027 | STUBBS, BRIANNA JANE | reporter.nih.gov |
| Investigating the interface of NLRX1 and immune aging | NIH | National Institute on Aging | 2024 to 2025 | $696,465 | September 1, 2024 | August 31, 2029 | KANG, INSOO | reporter.nih.gov |
| Developing an Anti-proteotoxicity Therapy for Neurodegenerative Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $694,318 | September 17, 2024 | August 31, 2027 | ZHANG, TAO | reporter.nih.gov |
| Stress-Induced Aging: Investigating Chronic Wound Stress as a Catalyst for Systemic Aging and Functional Decline | NIH | National Institute on Aging | 2025 | $686,700 | August 15, 2025 | July 31, 2027 | ROH, DANIEL SAM | reporter.nih.gov |
| Inhaled Stressors and Lung Aging | NIH | National Institute on Aging | 2025 | $667,664 | August 15, 2025 | July 31, 2027 | KLIMENT, CORRINE R | reporter.nih.gov |
| Geroprotective Precision Medicine Strategies in PWH that Use Alcohol | NIH | National Institute on Alcohol Abuse and Alcoholism | 2025 | $634,830 | September 25, 2025 | August 31, 2030 | WELSH, DAVID A | reporter.nih.gov |
| The Role of Hypothalamic Dysfunction in Accelerating Aging in Humans | NIH | National Institute on Aging | 2023 to 2025 | $634,701 | August 15, 2023 | April 30, 2028 | ALEKSIC, SANDRA | reporter.nih.gov |
| Senescence Cardiomyopathy | NIH | National Heart, Lung, and Blood Institute | 2025 | $631,261 | May 1, 2025 | February 28, 2029 | SADOSHIMA, JUNICHI | reporter.nih.gov |
| The Role of Mechanoaging in the Deterioration of Intestinal Homeostasis with Age | NIH | National Institute on Aging | 2025 | $629,562 | August 15, 2025 | July 31, 2030 | SAEIDI, NIMA | reporter.nih.gov |
| Midlife Obesity, Neurovascular Senescence and Cognitive Decline | NIH | National Institute on Aging | 2021 to 2025 | $600,780 | August 1, 2021 | July 31, 2026 | TARANTINI, STEFANO | reporter.nih.gov |
| Understanding the roles of prolonged fasting, calorie intake, and mTORC1 in the response to calorie restriction | NIH | National Institute on Aging | 2025 | $595,472 | August 1, 2025 | May 31, 2030 | LAMMING, DUDLEY WILLIAM | reporter.nih.gov |
| Using pharmacoepidemiology to optimize antihypertensive medication use to prevent aging-related multimorbidity: Midcareer investigator award in patient-oriented research and mentoring. | NIH | National Institute on Aging | 2023 to 2025 | $594,639 | February 1, 2023 | January 31, 2028 | BRESS, ADAM P | reporter.nih.gov |
| Activation of C/EBP-β by mitohormesis as a therapy for obesity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $588,501 | May 1, 2022 | January 31, 2027 | BITTO, ALESSANDRO | reporter.nih.gov |
| A pilot trial of skin barrier restoration to reduce systemic inflammation | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $540,056 | April 1, 2024 | March 31, 2027 | ABUABARA, KATRINA ELAINE | reporter.nih.gov |
| Mitochondrial modulation of neuroinflammation in AD and related tauopathies | NIH | National Institute on Aging | 2025 | $539,986 | September 15, 2020 | June 30, 2027 | WANG, XINGLONG | reporter.nih.gov |
| Mineral Scaffold-Modulated Senescence in Irradiated Bone | NIH | National Institute of Dental & Craniofacial Research | 2025 | $533,675 | July 1, 2025 | March 31, 2030 | HIXON, KATHERINE | reporter.nih.gov |
| Histone Expression in the Aging RPE | NIH | National Eye Institute | 2025 | $521,572 | January 1, 2025 | December 31, 2029 | KLEINMAN, MARK E | reporter.nih.gov |
| Effects of Genetic and Pharmacological Kynurenine Pathway Suppression on Healthspan, Lifespan, and Cellular Changes Associated with Aging in Mice | NIH | National Institute on Aging | 2022 to 2025 | $520,560 | May 15, 2022 | April 30, 2027 | WESTBROOK, REYHAN M. | reporter.nih.gov |
| The role of impaired mitophagy and mitochondrial dysfunction in glaucomatous neurodegeneration | NIH | National Eye Institute | 2024 to 2025 | $507,389 | September 30, 2021 | June 30, 2027 | MADDINENI, PRABHAVATHI | reporter.nih.gov |
| Role of stromal inflammatory signaling in the aging of lung resident lymphocytes | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $507,060 | August 15, 2023 | July 31, 2028 | ALLEN, NANCY CHRISTINE | reporter.nih.gov |
| Local and global epigenome regulation of senescence and aging | NIH | National Institute on Aging | 2025 | $506,404 | January 1, 2025 | December 31, 2025 | BERGER, SHELLEY L | reporter.nih.gov |
| The relationship between protein intake, gut microbiome, inflammaging and loss of mobility in older adults | NIH | National Institute on Aging | 2022 to 2025 | $503,712 | February 15, 2022 | November 30, 2026 | FARSIJANI, SAMANEH | reporter.nih.gov |
| Targeting Type 3 Diabetes (T3D) Mechanism of Alzheimer's Disease (AD) and AD-Related Dementias | NIH | National Institute on Aging | 2024 to 2025 | $499,990 | February 1, 2024 | January 31, 2027 | SUVOROV, ALEXANDER | reporter.nih.gov |
| Identity influences on psychosocial traits, biologic age, and cardiovascular disease disparities | NIH | National Institute on Aging | 2024 to 2025 | $493,020 | August 15, 2022 | December 31, 2025 | BEY, GANGA SARASVATI | reporter.nih.gov |
| Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | NIH | National Institute on Aging | 2024 to 2025 | $493,018 | August 1, 2020 | January 31, 2027 | TIAN, XIAO | reporter.nih.gov |
| Regulation and function of aged hematopoietic stem cell (HSC) niche | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $480,825 | September 1, 2023 | May 31, 2028 | GAO, XIN | reporter.nih.gov |
| Effect of small molecule activator of autophagy on insulin signaling, senescence, and neuropathology in mouse models of Alzheimer's disease | NIH | National Institute on Aging | 2025 | $479,375 | December 1, 2024 | November 30, 2026 | LAKSHMANA, MADEPALLI KRISHNAPPA | reporter.nih.gov |
| The role of cellular senescence in skeletal muscle loss and dysfunction | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $471,921 | September 20, 2024 | August 31, 2027 | ENGLUND, DAVIS A. | reporter.nih.gov |
| Network models to capture multiple outcomes resulting from multi-component, salutogenic interventions | NIH | National Center for Complementary & Integrative Health | 2023 to 2025 | $466,401 | August 4, 2023 | July 31, 2028 | CHAMBERLIN, STEVEN | reporter.nih.gov |
| Uncovering mechanisms that underpin bat virus virulence | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $455,692 | August 4, 2025 | July 31, 2027 | BROOK, CARA | reporter.nih.gov |
| Genetic insight into senescence from the Drosophila brain | NIH | National Institute on Aging | 2025 | $446,875 | September 1, 2025 | August 31, 2027 | BONINI, NANCY M | reporter.nih.gov |
| Genome-Wide CRISPR Activation: A Novel Strategy for Identifying Anti-Aging Targets | NIH | National Institute on Aging | 2024 to 2025 | $434,163 | May 1, 2024 | April 30, 2027 | APFELD, JAVIER | reporter.nih.gov |
| Genomic Instability-Induced Senescence in Brain Aging and Alzheimer's Disease | NIH | National Institute on Aging | 2025 | $432,280 | September 30, 2020 | March 31, 2026 | MONTAGNA, CRISTINA | reporter.nih.gov |
| Identification of Molecular Features Associated with Vascular Alterations in Aging | NIH | National Institute on Aging | 2025 | $431,750 | January 1, 2025 | December 31, 2026 | PASQUALINI, RENATA | reporter.nih.gov |
| Identify actionable drugs that enhance resilience in Alzheimer's disease individuals | NIH | National Institute on Aging | 2024 to 2025 | $429,000 | August 1, 2024 | April 30, 2027 | DAI, YULIN | reporter.nih.gov |
| Cellular senescence as a potential sex-specific driver of small vessel disease and post-stroke cognitive impairment in late adulthood | NIH | National Institute on Aging | 2024 to 2025 | $429,000 | September 15, 2024 | May 31, 2027 | RITZEL, RODNEY | reporter.nih.gov |
| Ultrastructural alterations to neuronal autophagy during aging delineated with Cryo-EM tomography | NIH | National Institute on Aging | 2025 | $429,000 | January 1, 2025 | December 31, 2026 | STAVOE, ANDREA | reporter.nih.gov |
| The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults | NIH | National Institute on Aging | 2023 to 2025 | $403,605 | March 15, 2023 | February 29, 2028 | KWON, OH SUNG | reporter.nih.gov |
| Targeting Cellular Senescence and RAGE in Type 2 Diabetes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $403,290 | May 1, 2021 | April 30, 2027 | FARR, JOSHUA NICHOLAS | reporter.nih.gov |
| A novel approach for targeting neuroinflammation in brain aging and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $397,462 | September 30, 2024 | June 30, 2027 | LAROCCA, THOMAS | reporter.nih.gov |
| Senescent periodontal ligament cells as a potential therapeutic target for age-associated periodontitis | NIH | National Institute of Dental & Craniofacial Research | 2025 | $385,116 | August 22, 2025 | May 31, 2030 | KITTAKA, MIZUHO | reporter.nih.gov |
| Molecular approach to ameliorate the age-dependent loss of Clock protein Bmal1 and Nrf2-antioxidant response in eye lens: Implications for eye lens health span | NIH | National Eye Institute | 2025 | $384,364 | September 1, 2025 | May 31, 2030 | SINGH, DHIRENDRA P | reporter.nih.gov |
| A Pipeline for Research, Education and Mentoring in Reproductive Aging | NIH | National Institute on Aging | 2023 to 2025 | $362,370 | May 15, 2023 | January 31, 2028 | GHAZI, ARJUMAND | reporter.nih.gov |
| Novel Therapy for Sarcopenia | NIH | National Institute on Aging | 2025 | $354,000 | September 20, 2025 | September 19, 2026 | LARRICK, JAMES W | reporter.nih.gov |
| Understanding of Essential Gene Function in Aging | NIH | National Institute on Aging | 2025 | $342,208 | July 1, 2024 | March 31, 2029 | KAYA, ALAATTIN | reporter.nih.gov |
| Utilizing senolytics to enhance the response to exercise in cachectic mice | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2024 to 2025 | $341,600 | August 15, 2024 | July 31, 2026 | DUNGAN, CORY | reporter.nih.gov |
| Impact of Exercise Adaptations on the Aging Stem Cell | NIH | National Institute of General Medical Sciences | 2024 to 2025 | $331,898 | September 1, 2024 | June 30, 2028 | LOGANATHAN, RAJPRASAD | reporter.nih.gov |
| Associations of biological aging with outcomes and immune dysregulation in multiple sclerosis | NIH | National Institute on Aging | 2024 to 2025 | $323,342 | July 1, 2024 | June 30, 2029 | ZHANG, YINAN | reporter.nih.gov |
| The Effect of Exercise on T Cell Aging in Rheumatoid Arthritis | NIH | National Institute on Aging | 2024 to 2025 | $321,284 | August 15, 2024 | April 30, 2029 | ANDONIAN, BRIAN JAMES | reporter.nih.gov |
| Expression of markers of type 2 diabetes-induced premature cellular senescence in gingival biopsies of individuals with periodontal health and periodontitis | NIH | National Institute of Dental & Craniofacial Research | 2025 | $307,000 | July 15, 2025 | July 14, 2027 | DUARTE, POLIANA MENDES | reporter.nih.gov |
| Primate epigenetic and senescence biomarkers to advance aging science and anti-aging strategies. | NIH | National Institute on Aging | 2025 | $291,913 | September 20, 2025 | September 19, 2026 | ELSWORTH, JOHN D | reporter.nih.gov |
| Targeting Hepatocyte Senescence to Improve NAFLD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $288,994 | March 1, 2024 | February 28, 2029 | DU, KUO | reporter.nih.gov |
| Geroscience Education and Training 2 (GET2) Network Collaborative | NIH | National Institute on Aging | 2025 | $262,808 | August 1, 2025 | July 31, 2028 | D'ANTONIO, PATRICIA M | reporter.nih.gov |
| Fatty acid remodeling of the translatome during fasting and aging | NIH | National Institute on Aging | 2024 to 2025 | $246,608 | September 13, 2024 | August 31, 2026 | YANG, HAOJUN | reporter.nih.gov |
| Targeting Mechanisms of Organelle Remodeling to Promote Healthy Aging | NIH | National Institute on Aging | 2025 | $244,999 | September 1, 2023 | August 31, 2028 | SHARMA, ARPIT | reporter.nih.gov |
| Understanding the role of the stromal cell niche in intestinal stem cell aging | NIH | National Institute on Aging | 2025 | $244,021 | August 1, 2023 | July 31, 2028 | GOTO, NORIHIRO | reporter.nih.gov |
| Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations (INSPIRE-COPD-E). | NIH | National Institute on Aging | 2025 | $243,000 | September 1, 2025 | June 30, 2030 | MOSHER, CHRISTOPHER | reporter.nih.gov |
| Elucidating the Mechanisms of Translational Approaches to Enhance Recovery of Aged Muscle | NIH | National Institute on Aging | 2023 to 2025 | $237,953 | September 15, 2021 | August 31, 2027 | PETROCELLI, JONATHAN JOSEPH | reporter.nih.gov |
| Enhancing Stem Cell Restoration of IOP Homeostasis by Senolytic Treatments | NIH | National Eye Institute | 2025 | $234,000 | February 1, 2025 | January 31, 2027 | KELLEY, MARY JANE | reporter.nih.gov |
| CD38 signaling in aging-associated immune responses induced by oral pathogens | NIH | National Institute of Dental & Craniofacial Research | 2025 | $226,500 | May 1, 2025 | April 30, 2027 | YU, HONG | reporter.nih.gov |
| Investigating protein supersaturation as a driver of aging | NIH | National Institute on Aging | 2023 to 2025 | $226,480 | April 1, 2023 | March 31, 2026 | VON SCHULZE, ALEX | reporter.nih.gov |
| Investigating the Mechanistic Role of Dietary Protein in Aging and in Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $225,750 | July 1, 2024 | December 31, 2026 | YEH, CHUNG-YANG | reporter.nih.gov |
| The pathogenic effects of senescent cells on their microenvironments and their role in human brain aging | NIH | National Institute on Aging | 2024 to 2025 | $223,623 | September 15, 2024 | November 13, 2025 | ZARE, HABIL | reporter.nih.gov |
| Immunological bases of the beneficial effects of exercise on skeletal muscle aging | NIH | National Institute on Aging | 2025 | $190,374 | September 1, 2025 | May 31, 2028 | LANGSTON, PAUL KENT | reporter.nih.gov |
| Microglial subpopulations that contribute to resilience to Alzheimers disease | NIH | National Institute on Aging | 2025 | $188,892 | January 1, 2025 | December 31, 2027 | PRATER, KATHERINE ELIZABETH | reporter.nih.gov |
| Optimizing autophagy to counteract aging-induced muscle deterioration in mice | NIH | National Institute of General Medical Sciences | 2025 | $170,900 | August 1, 2025 | July 31, 2029 | DOS SANTOS SILVA, KLEITON A | reporter.nih.gov |
| Investigating the Role of PLIN2 in Senescence | NIH | National Institute on Aging | 2022 to 2025 | $162,201 | July 5, 2022 | December 24, 2025 | DEVARAJAN, MAHIMA | reporter.nih.gov |
| Cardiometabolic disease and vascular aging: Klotho regulation of medial arterial calcification | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $159,980 | September 1, 2024 | August 31, 2026 | LIU, IRIS | reporter.nih.gov |
| The Post-Lung Transplant Impact of Alveolar Macrophage Senescence in Aged Donor Lungs | NIH | National Heart, Lung, and Blood Institute | 2025 | $158,652 | September 1, 2025 | August 31, 2030 | PATEL, KUNAL JATINKUMAR | reporter.nih.gov |
| Reversing age-related epigenetic changes and characterizing microglia heterogeneity in obesity and aging | NIH | National Institute on Aging | 2024 to 2025 | $155,887 | December 1, 2022 | January 31, 2028 | ANSERE, VICTOR AFRIYIE | reporter.nih.gov |
| Mitochondria-derived dsRNA in brain aging and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $152,324 | June 1, 2024 | May 31, 2027 | DOSER, RACHEL | reporter.nih.gov |
| Investigating Cellular Senescence at the Single Cell Level | NIH | National Institute on Aging | 2023 to 2025 | $151,728 | June 15, 2023 | June 14, 2026 | COHN, RACHEL | reporter.nih.gov |
| Reversal of Age-Associated Damage in the Planarian Germline | NIH | National Institute on Aging | 2023 to 2025 | $146,206 | February 1, 2023 | January 31, 2026 | VERDESCA, ANDREW | reporter.nih.gov |
| Regulation of cellular senescence and metabolic health by dietary protein | NIH | National Institute on Aging | 2023 to 2025 | $146,206 | April 3, 2023 | April 2, 2026 | CALUBAG, MARIAH | reporter.nih.gov |
| Mediators of Muscle Rejuvenation with Aging | NIH | National Institute on Aging | 2025 | $141,890 | June 1, 2025 | July 31, 2030 | MURACH, KEVIN | reporter.nih.gov |
| Cell-type specific role of melanocortin 4 receptor in inflammation and cognition with aging | NIH | National Institute on Aging | 2025 | $139,584 | June 1, 2025 | January 31, 2026 | SHARPE, AMANDA L | reporter.nih.gov |
| Microbiome Contributions to Age-Associated Cognitive Decline | NIH | National Institute on Aging | 2023 to 2025 | $126,282 | April 1, 2023 | March 31, 2026 | COX, TIMOTHY | reporter.nih.gov |
| Roles of Autophagy in Microglial Senescence and Parkinsons Disease | NIH | National Institute on Aging | 2025 | $125,361 | February 3, 2025 | April 30, 2028 | CHOI, INSUP | reporter.nih.gov |
| Determining the influence of metformin treatment on mitochondrial calcium flux during aerobic exercise training of healthy, aging rats | NIH | National Institute on Aging | 2024 to 2025 | $124,974 | June 1, 2024 | December 31, 2025 | O'REILLY, COLLEEN LOUISE | reporter.nih.gov |
| Senescent Cells Effects in Response to Pathogens | NIH | National Institute on Aging | 2025 | $124,875 | September 4, 2025 | May 31, 2030 | LANGHI PRATA, LARISSA GUTMAN PARANHOS | reporter.nih.gov |
| Mechanisms underlying a decline in neural stem cell migration during aging | NIH | National Institute on Aging | 2023 to 2025 | $123,628 | September 15, 2023 | December 14, 2026 | ZHOU, OLIVIA YU | reporter.nih.gov |
| Targeting cellular senescence with oral fisetin supplementation to improve vascular aging | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $123,314 | August 19, 2022 | November 30, 2025 | MAHONEY, SOPHIA ANDREA | reporter.nih.gov |
| Nuclear speckle liquid-liquid phase separation dynamics in senescence and aging | NIH | National Institute on Aging | 2023 to 2025 | $117,485 | April 1, 2023 | April 30, 2025 | DION, WILLIAM AARON | reporter.nih.gov |
| Sex-specific determinants of muscle quality in older adults | NIH | National Institute on Aging | 2025 | $116,710 | August 1, 2025 | April 30, 2030 | EARP, JACOB E | reporter.nih.gov |
| State-dependent gating of memory and plasticity in the aging brain | NIH | National Institute on Aging | 2025 | $107,097 | September 16, 2025 | June 30, 2027 | RAVEN, FRANK | reporter.nih.gov |
| uNDERSTANDING AND TARGETING SENESCENCE IN CLONAL HEMATOPOIESIS | NIH | National Cancer Institute | 2025 | $101,491 | January 1, 2025 | June 16, 2025 | FERNANDEZ MAESTRE, INES | reporter.nih.gov |
| Summer Training Course in Experimental Aging | NIH | National Institute on Aging | 2025 | $101,085 | May 1, 2018 | February 28, 2030 | KAPAHI, PANKAJ | reporter.nih.gov |
| Identifying novel contributors to Wnt/beta-catenin mediated epigenetic activity in the evolution of OSCC | NIH | National Institute of Dental & Craniofacial Research | 2024 to 2025 | $100,112 | May 8, 2024 | May 7, 2026 | FISHER, EMILY | reporter.nih.gov |
| Endogenous drivers of endothelial inflammation in Alzheimer's Disease | NIH | National Institute on Aging | 2024 to 2025 | $98,512 | August 16, 2024 | August 15, 2027 | SANBORN, MARK ALLEN | reporter.nih.gov |
| Using causal aging biomarkers and protein design to develop novel anti-aging interventions | NIH | National Institute on Aging | 2025 | $86,870 | September 3, 2024 | August 31, 2029 | YING, KEJUN | reporter.nih.gov |
| Aging-related Changes in the Neural Mechanisms Underlying Speech Motor Learning | NIH | National Institute on Aging | 2025 | $83,012 | September 16, 2024 | May 31, 2029 | WANG, HANTAO | reporter.nih.gov |
| Exploring Cumulative Social Determinants Burden, Cancer, and Accelerated Aging: The Role of Physical Activity as a Moderator | NIH | National Cancer Institute | 2025 | $80,500 | December 1, 2024 | November 30, 2026 | BELLIZZI, KEITH M | reporter.nih.gov |
| Circadian reprogramming in cellular senescence | NIH | National Institute on Aging | 2025 | $75,052 | September 29, 2025 | August 31, 2028 | DIETERT, KRISTI ANN | reporter.nih.gov |
| Role of Hypoxia-inducible factor-2α signaling in age-induced bone loss | NIH | National Institute on Aging | 2025 | $55,496 | December 15, 2024 | November 30, 2026 | MENDOZA, SARAH VANESSA | reporter.nih.gov |
| Sixteenth and Seventeenth International Symposia on Neurobiology and Neuroendocrinology of Aging | NIH | National Institute on Aging | 2024 to 2025 | $50,001 | December 1, 2023 | November 30, 2026 | BROWN-BORG, HOLLY M. | reporter.nih.gov |
| 53rd Annual Meeting of the American Aging Association | NIH | National Institute on Aging | 2025 | $50,000 | January 1, 2025 | December 31, 2025 | MILLER, BENJAMIN FRANCIS | reporter.nih.gov |
| Biological Science Program at the Gerontological Society of America's 2025 Annual Scientific Meeting | NIH | National Institute on Aging | 2025 | $50,000 | August 1, 2025 | July 31, 2026 | D'ANTONIO, PATRICIA M | reporter.nih.gov |
| Identifying Global Rejuvenation Mechanisms in Tissues that Reverses Age-Related Phenotypes in Planarians | NIH | National Institute on Aging | 2025 | $43,588 | September 1, 2025 | August 31, 2028 | ANACLETO, ANGELO | reporter.nih.gov |
| Brain Aging in Adults with Autism Spectrum Disorder | NIH | National Institute of Mental Health | 2025 | $42,895 | September 25, 2025 | September 24, 2027 | HALEY, EVAN | reporter.nih.gov |
| Cellular senescence in the pathogenesis of benign prostatic hyperplasia and associated lower urinary tract dysfunction | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $40,384 | September 1, 2025 | August 31, 2028 | LIMKAR, AJINKYA RAVINDRA | reporter.nih.gov |
| Characterizing concordance in the secretome of recessive dystrophic epidermolysis bullosa and cellular senescence | NIH | National Institute on Aging | 2025 | $37,697 | September 1, 2025 | August 31, 2028 | KOUTSOUKOS, STEFANOS ANTONIS | reporter.nih.gov |
| Mechanisms of adipose tissue functional decline with aging. | NIH | National Institute on Aging | 2025 | $36,751 | September 29, 2025 | September 28, 2026 | JANG, IN HWA | reporter.nih.gov |
| Alleviating Mitochondrial Dysfunction in PERK-deficient Neurodegenerative Disease | NIH | National Institute on Aging | 2025 | $36,538 | November 20, 2024 | March 31, 2027 | BARON, KELSEY ROSE | reporter.nih.gov |
| Elucidating mechanisms of mitochondrial DNA copy number regulation in aging | NIH | National Institute on Aging | 2025 | $34,859 | May 1, 2025 | April 30, 2028 | GARCIA, ARLENE | reporter.nih.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 313 | $188,163,720 | 0 | $0 |
| 2024 | 229 | $121,764,390 | 0 | $0 |
| 2023 | 150 | $99,617,585 | 0 | $0 |
| 2022 | 88 | $64,514,854 | 0 | $0 |
| 2021 | 45 | $45,436,318 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.