Data / Research funding / Fragile X Syndrome
Fragile X Syndrome: 150 NIH awards ($184.4M) to 68 organizations
150 NIH awards ($184.4M) in the NIH spending category Fragile X Syndrome, to 68 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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150 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE) | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $19,943,827 | September 30, 2001 | August 31, 2026 | GOLDSMITH, EDIE C | reporter.nih.gov |
| FMRP-mediated Regulation in Human Brain Development and Therapeutic Advancement | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $6,546,370 | September 25, 2020 | June 30, 2025 | JIN, PENG | reporter.nih.gov |
| Translational medicine and mechanistic studies of brain neurophysiology in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $6,538,717 | September 25, 2020 | June 30, 2025 | ERICKSON, CRAIG | reporter.nih.gov |
| Translational Control in Memory and Brain Disorders | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,426,946 | May 1, 2021 | April 30, 2029 | KLANN, ERIC | reporter.nih.gov |
| New mechanisms and technologies for understanding post-transcriptional gene regulation in neurons | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $5,391,456 | June 1, 2019 | May 31, 2027 | JAFFREY, SAMIE R | reporter.nih.gov |
| Mechanisms of Synaptic Transmission in Healthy and Disease States | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,140,156 | May 1, 2019 | April 30, 2027 | KLYACHKO, VITALY A | reporter.nih.gov |
| A Family Genetic Study of Autism and Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 to 2025 | $3,842,448 | May 1, 2012 | April 30, 2026 | LOSH, MOLLY C | reporter.nih.gov |
| Gene editing in the brain with CRISPR-PEG | NIH | National Institute of Mental Health | 2021 to 2025 | $3,288,527 | April 1, 2021 | January 31, 2027 | LEE, HYE YOUNG | reporter.nih.gov |
| Investigating mechanisms underlying impaired social and spatial cognition in rodent models of Fragile X syndrome | NIH | National Institute of Mental Health | 2022 to 2025 | $3,047,204 | August 1, 2022 | May 31, 2027 | COLGIN, LAURA L | reporter.nih.gov |
| BRITE-Eye: An integrated discovery engine for CNS therapeutic targets driven by high throughput genetic screens, functional readouts in human neurons, and machine learning | NIH | National Institute of Mental Health | 2023 to 2024 | $2,999,997 | September 19, 2023 | August 31, 2025 | WILLIAMS, LUIS ALBERTO | reporter.nih.gov |
| Association of the Fragile X Premutation with Cognitive and Behavioral Skills in Children | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,944,001 | September 1, 2021 | August 31, 2027 | HINTON, VERONICA J | reporter.nih.gov |
| Aging Symptom Trajectories in Mother Carriers of the FMR1 Premutation | NIH | National Institute on Aging | 2022 to 2025 | $2,847,621 | July 15, 2022 | March 31, 2027 | KLUSEK, JESSICA | reporter.nih.gov |
| Autonomic and Sensory Dysfunctions in FMR1 Conditions: Development, Mechanisms and Consequences | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $2,731,934 | July 8, 2022 | April 30, 2027 | ROBERTS, JANE E | reporter.nih.gov |
| The relationship between language and executive function in DLD and FXS over time | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $2,672,873 | August 15, 2021 | May 31, 2027 | STERLING, AUDRA MARIE | reporter.nih.gov |
| Genotype-Phenotype Relationships in Fragile X Families | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,496,604 | June 15, 1998 | May 31, 2028 | HAGERMAN, RANDI J. | reporter.nih.gov |
| Postnatal Oxytocin Treatment and Cognitive Function in Fragile X | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,479,522 | April 5, 2021 | September 30, 2026 | GALL, CHRISTINE M | reporter.nih.gov |
| Cerebellum and cerebellar-regulated circuit contribution to Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 to 2024 | $2,436,836 | July 1, 2020 | April 30, 2025 | TSAI, PETER T. | reporter.nih.gov |
| Trajectories and Markers of Neurodegeneration in Carriers of the Fragile X Premutation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,395,710 | June 1, 2007 | December 31, 2029 | HESSL, DAVID R | reporter.nih.gov |
| A molecular investigation of retinoic acid-dependent homeostatic synaptic plasticity | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,319,440 | May 1, 2020 | April 30, 2025 | CHEN, LU | reporter.nih.gov |
| Language and Executive Function in Females with ASD or FXS | NIH | National Institute on Deafness and Other Communication Disorders | 2023 to 2025 | $2,299,215 | September 1, 2023 | June 30, 2028 | STERLING, AUDRA MARIE | reporter.nih.gov |
| Nonsense-mediated mRNA decay and beyond | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $2,298,136 | August 1, 2023 | July 31, 2028 | MAQUAT, LYNNE E | reporter.nih.gov |
| Mechanism of Gp1 mGluR-dependent translation and plasticity | NIH | National Institute of Mental Health | 2021 to 2025 | $2,269,230 | December 1, 2020 | October 31, 2026 | TSAI, NIEN-PEI | reporter.nih.gov |
| Novel therapy for Fragile X syndrome | NIH | National Institute of Mental Health | 2021 to 2022 | $2,206,174 | September 15, 2017 | March 31, 2025 | TUCCI, FABIO COHEN | reporter.nih.gov |
| Emergence, stability, and predictors of anxiety in Fragile X syndrome | NIH | National Institute of Mental Health | 2023 to 2025 | $2,150,560 | September 1, 2016 | May 31, 2028 | HOGAN, ABIGAIL LEE | reporter.nih.gov |
| FX ENTRAIN: Perturbation of neurodynamics underlying sensory hyperarousal and statistical learning in Youth with FXS | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,143,187 | August 7, 2023 | July 31, 2028 | PEDAPATI, ERNEST VIJAY | reporter.nih.gov |
| Mechanisms of olfactory signal processing | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $2,072,411 | April 1, 2005 | March 31, 2027 | SCHOPPA, NATHAN ERIC | reporter.nih.gov |
| Connecting 3D genome misfolding to transcriptional silencing in fragile X syndrome | NIH | National Institute of Mental Health | 2021 to 2024 | $2,066,257 | August 15, 2019 | January 31, 2029 | PHILLIPS-CREMINS, JENNIFER ELIZABETH | reporter.nih.gov |
| Axonal FMRP in Synaptic Development | NIH | National Institute of Mental Health | 2021 to 2025 | $2,040,040 | September 20, 2021 | June 30, 2027 | WANG, YUAN | reporter.nih.gov |
| Cortical Interneuron Dysfunction in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $1,989,137 | April 1, 2022 | February 28, 2027 | PORTERA-CAILLIAU, CARLOS | reporter.nih.gov |
| Mechanism of Protein Synthesis and Translational Control | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,962,066 | June 1, 2021 | May 31, 2027 | JOSEPH, SIMPSON | reporter.nih.gov |
| CGG repeat associated translation in Fragile X-associated Tremor/Ataxia Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,869,734 | April 1, 2014 | December 31, 2025 | TODD, PETER K | reporter.nih.gov |
| Characterization of the role of Fmr1 in oxytocin neuronal subtypes | NIH | National Institute of Mental Health | 2021 to 2024 | $1,866,744 | February 1, 2020 | November 30, 2025 | DOLEN, GUL | reporter.nih.gov |
| Deciphering the roles of FXR1 in health and myopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,854,831 | August 1, 2022 | July 31, 2026 | GREGORIO, CAROL C | reporter.nih.gov |
| Circuit Defects Underlying Deficits in Social Touch in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $1,833,033 | August 1, 2024 | April 30, 2029 | PORTERA-CAILLIAU, CARLOS | reporter.nih.gov |
| Circuit Disruptions Underlying Atypical Sensory Processing in Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $1,820,216 | July 15, 2020 | March 31, 2025 | PORTERA-CAILLIAU, CARLOS | reporter.nih.gov |
| FXS: Late Adolescence and Early Adulthood | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $1,801,993 | April 1, 2016 | June 30, 2027 | BRADY, NANCY CAROLINE | reporter.nih.gov |
| FMRP Regulation of Gene Expression | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $1,796,124 | September 1, 2020 | August 31, 2025 | RICHTER, JOEL D | reporter.nih.gov |
| Mitochondrial control of protein translation in Fragile X | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,782,377 | June 1, 2019 | March 31, 2025 | JONAS, ELIZABETH ANN | reporter.nih.gov |
| RNA Control of Neural Function | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,773,265 | May 1, 2023 | February 29, 2028 | RICHTER, JOEL D | reporter.nih.gov |
| Neural Mechanisms of Predictive Impairments in Autism | NIH | National Institute of Mental Health | 2021 to 2025 | $1,768,787 | September 20, 2017 | February 29, 2028 | CHUBYKIN, ALEXANDER | reporter.nih.gov |
| Adults with Fragile X Syndrome: Health and Life Course Trajectories | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,709,403 | September 1, 2015 | May 31, 2028 | DAWALT, LEANN SMITH | reporter.nih.gov |
| Dopamine regulation of infant perceptual motor development and communication | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,695,044 | September 1, 2023 | June 30, 2028 | O'CONNELL, LAUREN A | reporter.nih.gov |
| Mitochondrial dysfunction in Fragile X: Mechanisms and treatments | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,572,277 | June 1, 2023 | May 31, 2028 | JONGENS, THOMAS A | reporter.nih.gov |
| Postnatal transient connectivity in brain development and implications in fragile x syndrome | NIH | National Institute of Mental Health | 2024 to 2025 | $1,476,039 | July 1, 2024 | January 31, 2029 | POUCHELON, GABRIELLE | reporter.nih.gov |
| Myelination Deficits Underlying Auditory Issues in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $1,449,156 | September 9, 2021 | July 31, 2028 | MCCULLAGH, ELIZABETH ANNE | reporter.nih.gov |
| Defining post-transcriptional gene regulation in FMRP-deficiency usingmiRNA:target chimeras | NIH | National Institute of Mental Health | 2023 to 2025 | $1,447,055 | January 1, 2023 | November 30, 2027 | MEFFERT, MOLLIE KATHERINE | reporter.nih.gov |
| Interrogate FMRP functions in primate brain development | NIH | National Institute of Mental Health | 2024 to 2025 | $1,435,409 | May 1, 2024 | February 28, 2029 | ZHAO, XINYU | reporter.nih.gov |
| Astroglia-Mediated Pathogenic Mechanisms in Fragile X Syndrome (FXS) | NIH | National Institute of Mental Health | 2023 to 2025 | $1,432,014 | May 15, 2016 | April 30, 2026 | YANG, YONGJIE | reporter.nih.gov |
| A lipid-induced RNA-binding protein in atherosclerosis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,401,825 | April 1, 2020 | March 31, 2025 | DIMAYUGA, PAUL C. | reporter.nih.gov |
| The Role of Astrocytes in the Fragile X Pathogenesis | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,371,795 | January 1, 2019 | December 31, 2024 | DUNAEVSKY, ANNA | reporter.nih.gov |
| Nonconventional role of ADCY in Gq-mediated neuronal signaling and neuroplasticity | NIH | National Institute of Mental Health | 2021 to 2023 | $1,343,860 | April 1, 2019 | January 31, 2025 | WANG, HONGBING | reporter.nih.gov |
| Identifying Convergent Circuit Disruptions Across Genetically-Distinct Models of Autism | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $1,251,466 | September 22, 2023 | May 31, 2028 | AUERBACH, BENJAMIN D | reporter.nih.gov |
| Therapeutic Potential of Rescued FMR1 Mis-Splicing in Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $1,243,688 | June 1, 2023 | May 31, 2028 | RICHTER, JOEL D | reporter.nih.gov |
| Fragile X-associated tremor/ataxia syndrome (FXTAS) pathology and anatomy: imaging and clinical correlates | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $1,212,893 | September 1, 2018 | May 31, 2024 | MARTINEZ-CERDENO, VERONICA | reporter.nih.gov |
| Language Development in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $1,199,669 | September 1, 1987 | May 31, 2024 | ABBEDUTO, LEONARD J. | reporter.nih.gov |
| FMRP regulation of mitochondria and metabolism in mammalian brain development | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,199,340 | September 1, 2024 | May 31, 2029 | ZHAO, XINYU | reporter.nih.gov |
| Mechanisms and biomarkers of disease progression in Fragile X-associated tremor/ataxia syndrome (FXTAS) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,198,205 | January 26, 2024 | November 30, 2028 | MOSCONI, MATTHEW W | reporter.nih.gov |
| Molecular Basis of rCGG-Mediated Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $1,180,305 | January 1, 2006 | January 31, 2025 | NELSON, DAVID LOREN | reporter.nih.gov |
| Physiological mechanisms underlying disrupted hippocampal function in Fragile X syndrome | NIH | National Institute of Mental Health | 2021 to 2022 | $1,173,890 | November 16, 2020 | October 31, 2023 | COLGIN, LAURA L | reporter.nih.gov |
| Clinical Outcome Assessment and Treatment Monitoring Markers for Clinical Trial Readiness in FXTAS | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $1,169,064 | July 15, 2025 | June 30, 2030 | HESSL, DAVID R | reporter.nih.gov |
| FXTAS Key Molecular Pathways Converge with Other Neurodegenerative Disorders | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $1,104,854 | April 15, 2022 | March 31, 2027 | LOZANO, REYMUNDO | reporter.nih.gov |
| Crosstalk between DNA repair pathways in repeat instability | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $1,075,966 | February 1, 2023 | December 31, 2026 | PLUCIENNIK, ANNA | reporter.nih.gov |
| Developmental trajectory of anxiety, avoidance, and arousal in girls with the FMR1 full mutation | NIH | National Institute of Mental Health | 2021 to 2022 | $918,068 | May 1, 2022 | August 31, 2023 | REISS, ALLAN L | reporter.nih.gov |
| The Role of MDM2 in FMRP regulation of neuronal development | NIH | National Institute of Mental Health | 2021 to 2022 | $917,272 | July 9, 2018 | April 30, 2024 | ZHAO, XINYU | reporter.nih.gov |
| Nonsense-Mediated mRNA Decay and Nonsense-Mediated mRNA Decay Factors | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $884,498 | August 1, 1999 | July 31, 2023 | MAQUAT, LYNNE E | reporter.nih.gov |
| Glial roles in experience-dependent critical period remodeling | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $815,738 | April 1, 2024 | March 31, 2029 | BROADIE, KENDAL | reporter.nih.gov |
| Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | NIH | National Institute of Mental Health | 2023 to 2024 | $805,000 | September 1, 2023 | December 15, 2024 | LOUVEAU, ANTOINE | reporter.nih.gov |
| Neural Markers of Language Development in Fragile X Syndrome and Autism Spectrum Disorder | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2024 | $687,216 | April 1, 2020 | March 31, 2025 | WILKINSON, CAROL LEE | reporter.nih.gov |
| Mechanisms of sound hypersensitivity in a rat model of autism | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2024 | $649,145 | April 10, 2020 | March 31, 2026 | AUERBACH, BENJAMIN D | reporter.nih.gov |
| Tracking early emergence of sound perception impairments in FXS with multimodal fNIRS/EEG | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2025 | $608,612 | September 1, 2022 | August 31, 2027 | SMITH, ELIZABETH GAYLE | reporter.nih.gov |
| Deciphering the roles of FXR1 in health and myopathy | NIH | National Heart, Lung, and Blood Institute | 2022 | $601,489 | August 1, 2022 | April 30, 2023 | GREGORIO, CAROL C | reporter.nih.gov |
| Connecting 3D genome misfolding to transcriptional silencing in fragile X syndrome | NIH | National Institute of Mental Health | 2025 | $555,605 | August 15, 2019 | January 31, 2029 | PHILLIPS-CREMINS, JENNIFER ELIZABETH | reporter.nih.gov |
| Genetic and Developmental Analyses of Fragile X Mental Retardation Protein | NIH | National Institute of Mental Health | 2023 | $516,155 | August 15, 2009 | November 30, 2024 | BROADIE, KENDAL | reporter.nih.gov |
| Contribution of Glia to Sleep/Wake Disturbances in FXS | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $515,898 | April 1, 2025 | February 28, 2030 | DUNAEVSKY, ANNA | reporter.nih.gov |
| Biochemical characterization of a novel Fragile X Mental Retardation Protein nuclease function | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $514,000 | July 1, 2005 | August 31, 2025 | MIHAILESCU, MIHAELA R | reporter.nih.gov |
| Unraveling the Impact of Extracellular Vesicle-Loaded FXR1 mRNA on Re-educating Cancer Microenvironment | NIH | National Cancer Institute | 2025 | $494,160 | September 11, 2025 | August 31, 2030 | CHALUVALLY-RAGHAVAN, PRADEEP | reporter.nih.gov |
| Attenuation of atherosclerosis by regulation of VSMC inflammatory gene mRNA stability | NIH | National Heart, Lung, and Blood Institute | 2021 | $491,772 | February 1, 2018 | January 31, 2024 | AUTIERI, MICHAEL V | reporter.nih.gov |
| Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development | NIH | National Institute on Deafness and Other Communication Disorders | 2023 to 2025 | $489,542 | April 1, 2021 | March 31, 2026 | SAKANO, HITOMI | reporter.nih.gov |
| Human cerebral organoids as a model system for neural development and disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $488,040 | August 1, 2020 | July 31, 2024 | WATANABE, MOMOKO | reporter.nih.gov |
| Electrophysiological Biomarkers of Neurocognitive Deficits in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $482,280 | April 1, 2020 | December 2, 2024 | SCHMITT, LAUREN | reporter.nih.gov |
| Genetic and Developmental Analyses of Fragile X Mental Retardation Protein | NIH | National Institute of Mental Health | 2021 | $476,491 | August 15, 2009 | November 30, 2022 | BROADIE, KENDAL | reporter.nih.gov |
| Neurodegenerative mechanisms of motor, executive, and memory decline in females with Fragile X-associated tremor/ataxia syndrome (FXTAS) | NIH | National Institute on Aging | 2023 to 2024 | $465,831 | February 15, 2023 | January 31, 2025 | MOSCONI, MATTHEW W | reporter.nih.gov |
| Elucidating Fragile X Syndrome by Investigating FMRP Molecular Function | NIH | National Institute of Mental Health | 2023 | $460,625 | July 7, 2023 | July 6, 2025 | RICHTER, JOEL D | reporter.nih.gov |
| A new diagnostic tool for rapid detection and characterization of REPEAT SEQUENCES in inherited diseases | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2022 to 2023 | $459,016 | August 15, 2022 | December 31, 2024 | REED, JASON C | reporter.nih.gov |
| Understanding the Genome Maintenance Function of the Fragile X Protein (FMRP) | NIH | National Institute of Mental Health | 2022 to 2023 | $448,250 | July 15, 2022 | June 30, 2025 | FENG, WENYI | reporter.nih.gov |
| Molecular mechanisms of glial-mediated synapse alterations in Fragile X syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $445,500 | April 1, 2021 | September 30, 2023 | MASON, CAROL A. | reporter.nih.gov |
| Localized translational dysregulation in an autism spectrum disorder model using in situ cryo-EM | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $443,121 | July 1, 2024 | June 30, 2026 | LOERCH, SARAH | reporter.nih.gov |
| Multilevel Analysis of Cortical Interneuron Dysfunction in Fragile X Syndrome | NIH | National Institute of Mental Health | 2023 to 2024 | $442,160 | December 1, 2022 | November 30, 2025 | AU, EDMUND | reporter.nih.gov |
| Defining Plasticity and Homeostasis in Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 | $439,297 | July 1, 2021 | June 30, 2023 | HUNTSMAN, MOLLY-MAUREEN | reporter.nih.gov |
| Determining whether metabolic and mitochondrial pathophysiology are a common feature of three distinct genetic models of ASD | NIH | National Institute of Mental Health | 2022 to 2023 | $439,263 | December 3, 2021 | November 30, 2024 | JONGENS, THOMAS A | reporter.nih.gov |
| Contributors to FXTAS Progression | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $439,250 | July 1, 2022 | June 30, 2025 | GIULIVI, CECILIA | reporter.nih.gov |
| Transcriptional Mechanism underlying Neuronal Hyperexcitability in FXS | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $436,150 | June 1, 2023 | May 31, 2026 | TSAI, NIEN-PEI | reporter.nih.gov |
| Fmr1 Function and Repeat Expansion in the Developing Germline | NIH | National Institute of General Medical Sciences | 2021 | $435,875 | December 26, 2017 | November 30, 2022 | LAIRD, DIANA J | reporter.nih.gov |
| Developing an Astroglial Model for Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $434,385 | August 1, 2021 | January 31, 2025 | DUNAEVSKY, ANNA | reporter.nih.gov |
| A Novel Role of Fragile-X Mental Retardation Protein in Mitochondrial Calcium Homeostasis | NIH | National Institute of Mental Health | 2022 to 2023 | $432,850 | May 1, 2022 | April 30, 2024 | LU, BINGWEI | reporter.nih.gov |
| Interrogating neurogenic defects in complex assembloid models of fragile X syndrome | NIH | National Institute of Mental Health | 2023 | $430,375 | August 15, 2023 | August 14, 2025 | RAJ, NISHA | reporter.nih.gov |
| Single-Molecule Imaging of Ubiquitination Dynamics in Neurons | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $430,375 | September 15, 2023 | August 31, 2025 | BASSELL, GARY J | reporter.nih.gov |
| Membrane trafficking impairments in fragile x syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $430,375 | July 1, 2025 | June 30, 2027 | BASSELL, GARY J | reporter.nih.gov |
| Discovery of small molecule activators of the Slack potassium channel for use as cell-based probes for the study of fragile X syndrome | NIH | National Institute of Mental Health | 2021 to 2022 | $428,348 | December 1, 2020 | October 31, 2023 | EMMITTE, KYLE A | reporter.nih.gov |
| Unraveling the role of satellite glial cells in sensory hypersensitivity in Fragile X syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 | $427,625 | September 6, 2023 | August 31, 2025 | CAVALLI, VALERIA | reporter.nih.gov |
| Unraveling satellite glial cells dysfunctions in spiral ganglia of a mouse model of Fragile X syndrome | NIH | National Institute on Deafness and Other Communication Disorders | 2024 to 2025 | $427,625 | March 1, 2024 | February 28, 2026 | CAVALLI, VALERIA | reporter.nih.gov |
| Pathophysiology and treatment of fragile X and related disorders | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $426,523 | March 1, 2022 | February 29, 2024 | BEAR, MARK F | reporter.nih.gov |
| Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2023 | $425,749 | April 1, 2021 | July 31, 2023 | SAKANO, HITOMI | reporter.nih.gov |
| Mechanisms of FMR1 gene-mediated reproductive disorders | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2025 | $425,628 | August 1, 2025 | July 31, 2027 | COSS, DJURDJICA | reporter.nih.gov |
| Establishing Drosophila melanogaster as a model for developmental neurotoxicity assessment of air pollutants using diesel exhaust | NIH | National Institute of Environmental Health Sciences | 2024 | $421,705 | June 13, 2024 | May 31, 2027 | MILLER-SCHULZE, JUSTIN P. | reporter.nih.gov |
| Reactivation of Epigenetically Silenced FMR1 as a Therapeutic Approach for Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 | $418,750 | July 1, 2017 | June 30, 2022 | GREEN, MICHAEL R | reporter.nih.gov |
| Dysregulation of mTORC2 and cofilin signaling in Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 | $417,500 | January 1, 2011 | April 30, 2023 | ZUKIN, R. SUZANNE | reporter.nih.gov |
| Language as a Candidate Marker of FXTAS in FMR1 Premutation Carriers | NIH | National Institute on Deafness and Other Communication Disorders | 2023 to 2024 | $373,437 | September 16, 2022 | July 31, 2025 | MALTMAN, ALEXIS NELL | reporter.nih.gov |
| Neural coordination and discoordination in Fmr1 null mice | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $343,384 | August 15, 2017 | April 30, 2022 | FENTON, ANDRE ANTONIO | reporter.nih.gov |
| Impact of Child and Maternal Gestures on Word Learning in Fragile X Syndrome | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2022 | $303,114 | August 1, 2020 | July 31, 2025 | MATTIE, LAURA J | reporter.nih.gov |
| The Histone Code of Neuronal Function and Dysfunction | NIH | National Institute of Mental Health | 2021 | $247,106 | January 1, 2019 | November 30, 2021 | KORB, ERICA MEGAN | reporter.nih.gov |
| Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | NIH | National Institute of Mental Health | 2025 | $241,500 | December 16, 2024 | November 30, 2029 | LOUVEAU, ANTOINE | reporter.nih.gov |
| Mechanisms of microRNA dysregulation in Fragile X Syndrome | NIH | National Institute of Mental Health | 2023 to 2025 | $226,480 | September 13, 2023 | September 12, 2026 | KOSTI, ADAM | reporter.nih.gov |
| Sensory Hypersensitivity in Fragile X Syndrome Due to Deficits in Tonic Inhibition Reversed by Neuroactive Steroids | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $204,300 | April 1, 2020 | March 31, 2022 | DAVIES, PAUL ANDREW | reporter.nih.gov |
| Mechanisms of Loudness Intolerance in a Rat Model of Fragile X | NIH | National Institute on Deafness and Other Communication Disorders | 2021 | $199,375 | April 1, 2020 | March 31, 2022 | SALVI, RICHARD J | reporter.nih.gov |
| Metabolic Dysregulation in FXTAS Pathogenesis | NIH | National Institute on Aging | 2021 | $197,700 | August 1, 2020 | April 30, 2023 | ALLEN, EMILY GRAVES | reporter.nih.gov |
| Language as a Candidate Marker of FXTAS in FMR1 Premutation Carriers | NIH | National Institute on Deafness and Other Communication Disorders | 2022 to 2023 | $196,875 | September 16, 2022 | August 31, 2023 | MALTMAN, ALEXIS NELL | reporter.nih.gov |
| Reelin and Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $187,500 | January 3, 2025 | December 31, 2026 | NASH, KEVIN RON | reporter.nih.gov |
| Anomalous Sensorimotor Physiology in Fragile X Syndrome | NIH | National Institute of Mental Health | 2021 | $179,583 | April 7, 2017 | March 31, 2022 | PEDAPATI, ERNEST VIJAY | reporter.nih.gov |
| The Role of Astrocyte BMP Signaling in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2024 | $174,515 | September 1, 2021 | August 31, 2025 | DENG, JAMES DERONG | reporter.nih.gov |
| Mechanistic underpinnings of pragmatics in ASD: Insights from FMR1-mutation conditions | NIH | National Institute on Deafness and Other Communication Disorders | 2024 | $160,000 | September 24, 2024 | August 31, 2026 | LOSH, MOLLY C | reporter.nih.gov |
| Fragile X messenger ribonucleoprotein-1 mediated regulation of the Clathrin-Associated Adaptor Complex Protein-2 (AP2) | NIH | National Institute of Mental Health | 2024 | $156,500 | January 1, 2024 | December 31, 2025 | BASSELL, GARY J | reporter.nih.gov |
| Defining the Language Phenotype of the FMR1 Premutation | NIH | National Institute on Deafness and Other Communication Disorders | 2021 | $146,500 | April 1, 2019 | March 31, 2024 | KLUSEK, JESSICA | reporter.nih.gov |
| Vocabulary Acquisition in a Meaningful Context: Differentiating Learning Profiles for Autism Spectrum Disorder and Fragile X Syndrome | NIH | National Institute on Deafness and Other Communication Disorders | 2021 | $145,674 | September 1, 2019 | August 31, 2024 | KOVER, SARA TERESA | reporter.nih.gov |
| Elucidating the RNA-mediated mechanisms governing H3K9me3 deposition in fragile X syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $143,420 | September 1, 2022 | December 29, 2025 | MALACHOWSKI, THOMAS ERNST | reporter.nih.gov |
| Understanding the role of the frontal cortex during cognitive flexibility in Fmr1 knock outs | NIH | National Institute of Mental Health | 2023 to 2024 | $143,408 | March 1, 2023 | February 28, 2026 | PLAKKE ANDERSON, BETHANY | reporter.nih.gov |
| Establishing Drosophila melanogaster as a model for determining gene-environment interactions that confer risk of autism using bisphenols and the autism risk gene, fragile x mental retardation 1 | NIH | National Institute of General Medical Sciences | 2021 | $142,000 | June 10, 2019 | May 31, 2024 | MULLIGAN, KIMBERLY ANNE | reporter.nih.gov |
| ISRIB as a promising therapeutic for Fragile X syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $140,296 | July 17, 2020 | July 16, 2023 | COULSON, ROCHELLE LYNN | reporter.nih.gov |
| Examining the role of specific NMDA receptor subunits in cortical circuit dysfunction in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $118,420 | September 1, 2023 | August 31, 2026 | SHEDD, ALEYA MICHELLE | reporter.nih.gov |
| Astrocyte-neuron interactions in Rett Syndrome and Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $118,395 | August 7, 2025 | February 28, 2027 | LYON, KRISTINE ANNE | reporter.nih.gov |
| Elucidating the spatially coordinated mechanisms of transcriptional silencing in fragile X syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $108,512 | March 1, 2024 | February 28, 2028 | PHAM, KENNETH | reporter.nih.gov |
| Characterizing the regulatory roles of microRNA on mitochondria in the mammalian CNS | NIH | National Institute of Mental Health | 2024 to 2025 | $104,512 | September 5, 2024 | March 4, 2027 | EISS, EMILY | reporter.nih.gov |
| Characterization of Fragile X Syndrome 3D Cortical Organoids | NIH | National Institute of Mental Health | 2024 to 2025 | $90,739 | March 8, 2024 | February 28, 2026 | SANDOVAL, SORAYA OROZCO | reporter.nih.gov |
| Mechanisms underlying impaired hippocampal physiology in Fragile X Syndrome | NIH | National Institute of Mental Health | 2022 to 2023 | $87,990 | June 1, 2022 | July 31, 2024 | DONAHUE, MARGARET MCNEIL | reporter.nih.gov |
| Maternal-Child RSA Synchrony in Infants with Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $85,712 | February 1, 2024 | January 31, 2027 | HANTMAN, RACHEL | reporter.nih.gov |
| Mechanisms of Setd2 in cortical circuit function: Convergence with Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $81,576 | January 5, 2024 | November 4, 2026 | POPE, ALEXANDER | reporter.nih.gov |
| Health Disparities of Patients with Fragile X from Diverse Racial & Ethnic Groups | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 | $77,750 | April 6, 2023 | November 13, 2023 | MOVAGHAR, AREZOO | reporter.nih.gov |
| Health Disparities of Patients with Fragile X from Diverse Racial & Ethnic Groups | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $75,501 | April 6, 2023 | March 31, 2026 | MOVAGHAR, AREZOO | reporter.nih.gov |
| Characterization of the Attentional Profile in Women and Girls with a Fragile X Premutation Allele | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $68,232 | June 1, 2024 | February 14, 2027 | RUSSELL-GILLER, SHIRA | reporter.nih.gov |
| Impact of Cognitive function on Balance and Gait Markers for FXTAS | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $62,465 | July 7, 2016 | June 30, 2022 | O'KEEFE, JOAN A | reporter.nih.gov |
| Elucidating the interplay between cohesin-mediated loop extrusion and heterochromatin in single cells. | NIH | National Human Genome Research Institute | 2025 | $48,974 | January 1, 2025 | December 31, 2027 | PATEL, ROHAN DIPAK | reporter.nih.gov |
| CGG repeat associated translation in Fragile X gene function and disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $46,030 | May 1, 2020 | July 31, 2022 | WRIGHT, SHANNON | reporter.nih.gov |
| The cadence of social communication: Unraveling speech rhythm and underlying neural, motor, and genetic mechanisms. | NIH | National Institute on Deafness and Other Communication Disorders | 2025 | $44,751 | December 1, 2025 | May 31, 2027 | ETHRIDGE, SARAH | reporter.nih.gov |
| Network mechanisms underlying core behavioral features in Fragile X Syndrome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $42,574 | August 16, 2024 | August 15, 2026 | NORRIS, JORDAN | reporter.nih.gov |
| The roles of Fragile-X related protein 1 in cardiomyocyte and heart biology | NIH | National Heart, Lung, and Blood Institute | 2024 | $41,627 | December 1, 2024 | November 30, 2027 | BAIS, GABRIELLE | reporter.nih.gov |
| Language, physiology, and anxiety across contexts in autism spectrum disorder and fragile X syndrome | NIH | National Institute on Deafness and Other Communication Disorders | 2021 | $38,124 | July 1, 2020 | June 30, 2022 | LORANG, EMILY KATHRYN | reporter.nih.gov |
| FXR1 Regulates Blood Pressure by Altering Contraction of Smooth Muscle | NIH | National Heart, Lung, and Blood Institute | 2022 | $31,586 | July 1, 2022 | June 8, 2023 | ST. PAUL, AMANDA | reporter.nih.gov |
| Trinucleotide repeat disorders and the 3D genome | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $25,721 | September 1, 2019 | May 16, 2022 | ZHOU, LINDA | reporter.nih.gov |
| Cellular and molecular mechanisms of auditory processing deficits in a mouse model of Fragile X Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $18,944 | April 1, 2020 | June 25, 2021 | RAIS, MAHAM | reporter.nih.gov |
| 2024 Fragile X and Autism-Related Disorders Gordon Research Conference and Gordon Research Seminar | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $15,000 | April 1, 2024 | March 31, 2025 | HUBER, KIMBERLY M. | reporter.nih.gov |
Organizations
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 65 | $34,771,701 | 0 | $0 |
| 2024 | 78 | $39,217,327 | 0 | $0 |
| 2023 | 82 | $41,547,514 | 0 | $0 |
| 2022 | 65 | $34,065,201 | 0 | $0 |
| 2021 | 71 | $34,824,114 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.