Data / Research funding / Esophageal Cancer

Esophageal Cancer: 123 NIH awards ($160.1M) to 62 organizations

Name: NIH and NSF awards on Esophageal Cancer
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

123 NIH awards ($160.1M) in the NIH spending category Esophageal Cancer, to 62 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

Get awards on Esophageal Cancer Watch Esophageal Cancer

Topic: NIH spending category

Awards

123 awards in the window.

Award	Agency	Institute or division	Fiscal year	Amount in window	Start	End	Principal investigator	Source
A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT Trial	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2022 to 2025	$8,184,774	May 15, 2022	April 30, 2027	WANI, SACHIN	reporter.nih.gov
The role of stem cells and the microenvironment in gastrointestinal cancers	NIH	National Cancer Institute	2021 to 2025	$5,569,272	January 7, 2016	August 31, 2030	WANG, TIMOTHY CRAGIN	reporter.nih.gov
Gastroesophageal junction stem cells as the origin of Barretts esophagus and cancer	NIH	National Cancer Institute	2022 to 2025	$4,948,268	September 1, 2025	August 31, 2027	WANG, TIMOTHY CRAGIN	reporter.nih.gov
Initiation of Diffuse and Intestinal Non-Cardia Gastric Cancer	NIH	National Cancer Institute	2022 to 2025	$4,080,056	September 1, 2025	August 31, 2027	RYEOM, SANDRA	reporter.nih.gov
Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablation	NIH	National Cancer Institute	2022 to 2025	$3,855,091	September 22, 2022	August 31, 2027	MARKOWITZ, SANFORD D.	reporter.nih.gov
Genetics, Epigenetics, and Risk Prediction for Esophageal Adenocarcinoma	NIH	National Cancer Institute	2022 to 2025	$3,588,780	September 12, 2022	August 31, 2027	KOOPERBERG, CHARLES L	reporter.nih.gov
Improving radiolabeled imaging and targeting of HER2 positive EG cancers using lovastatin	NIH	National Cancer Institute	2021 to 2025	$3,432,890	December 1, 2020	November 30, 2026	LEWIS, JASON S.	reporter.nih.gov
The Role of Secondary Bile Acids in Gastro-Esophageal Neoplasia	NIH	National Cancer Institute	2022 to 2025	$3,273,998	September 1, 2022	August 31, 2027	ABRAMS, JULIAN	reporter.nih.gov
Low Cost Tethered Capsule Endoscope with High-Resolution Digital Chromoscopy for Barrett's Screening	NIH	National Cancer Institute	2021 to 2025	$3,157,352	July 1, 2021	June 30, 2027	RICHARDS-KORTUM, REBECCA R.	reporter.nih.gov
Coordinating Center for the Program on the Origins of Gastroesophageal Cancers	NIH	National Cancer Institute	2022 to 2025	$3,140,717	September 6, 2022	August 31, 2027	HUR, CHIN	reporter.nih.gov
The Ecology of Barrett's Esophagus	NIH	National Cancer Institute	2025	$3,130,492	August 22, 2025	July 31, 2029	MALEY, CARLO	reporter.nih.gov
Serial immunotherapy combination to modulate the tumor environment in patients with metastatic gastroesophageal cancer	NIH	National Cancer Institute	2021 to 2025	$3,119,133	January 1, 2021	December 31, 2026	YOON, HARRY H	reporter.nih.gov
The Role of the Microbiome and Notch Signaling in Esophageal Adenocarcinoma	NIH	National Cancer Institute	2021 to 2025	$3,108,327	January 1, 2021	December 31, 2026	ABRAMS, JULIAN	reporter.nih.gov
Common Stem Cell of Origin for Junctional and Gastric Adenocarcinoma	NIH	National Cancer Institute	2022 to 2024	$2,754,572	September 15, 2022	August 31, 2027	MCKEON, FRANK D.	reporter.nih.gov
HORMAD-specific TGF-beta resistant memory T cells for treatment of patients with Gastro-esophageal Cancer	NIH	National Cancer Institute	2023 to 2024	$2,717,589	September 19, 2023	August 31, 2025	YEE, CASSIAN	reporter.nih.gov
CardioWatch: An Omics-Based Prediction Assay for Cardiac Late Effects ofAcute Radiation	NIH	National Institute of Allergy and Infectious Diseases	2023 to 2025	$2,645,440	July 1, 2020	July 31, 2027	KANHOLM, TOMAS	reporter.nih.gov
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided Biopsy	NIH	National Institute of Biomedical Imaging and Bioengineering	2022 to 2025	$2,559,999	September 30, 2022	June 30, 2027	TEARNEY, GUILLERMO J	reporter.nih.gov
Designing a Plan of Action for Better Access and Quality of Surgery for African-Americans with Gastrointestinal Cancers in the Deep South	NIH	National Institute on Minority Health and Health Disparities	2021 to 2024	$2,406,877	June 15, 2020	January 31, 2026	PISU, MARIA	reporter.nih.gov
NRF2-ACSS2 Axis in Alcohol-induced Metabolic Reprogramming and Esophageal Pathology	NIH	National Institute on Alcohol Abuse and Alcoholism	2022 to 2025	$2,359,087	August 1, 2022	July 31, 2027	CHEN, XIAOXIN LUKE	reporter.nih.gov
Genetic susceptibility to Barrett's esophagus: From GWAS to biology	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2023 to 2025	$2,315,127	December 21, 2021	November 30, 2026	BUAS, MATTHEW FRANK	reporter.nih.gov
HORMAD-specific TGF-beta resistant memory T cells for treatment of patients with Gastro-esophageal Cancer	NIH	National Cancer Institute	2025	$2,270,520	September 19, 2023	August 31, 2028	YEE, CASSIAN	reporter.nih.gov
Consequences of retrotransposition on genome integrity	NIH	National Cancer Institute	2023 to 2025	$2,208,749	August 1, 2023	July 31, 2028	BURNS, KATHLEEN H	reporter.nih.gov
Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer	NIH	National Cancer Institute	2022 to 2024	$2,059,739	April 1, 2022	March 31, 2025	BOEHM, JESSE SAMUEL	reporter.nih.gov
Endoscope development for the clinical use of near infrared fluorescence molecular probes in the GI tract	NIH	National Cancer Institute	2021 to 2022	$1,995,368	September 23, 2021	August 31, 2025	MCMORROW, GERALD	reporter.nih.gov
A Personalized Approach to Targeted Esophageal Cancer Screening	NIH	National Cancer Institute	2021 to 2024	$1,992,292	July 8, 2020	June 30, 2026	HUR, CHIN	reporter.nih.gov
Development of Notch1-selective Small Molecule Inhibitor for the Treatment of Cancer	NIH	National Cancer Institute	2021 to 2022	$1,976,591	September 1, 2021	August 31, 2023	FEI, DENNIS LIANG	reporter.nih.gov
Optimization and validation of a biomarker panel for risk stratification in Barrett's esophagus	NIH	National Cancer Institute	2023 to 2025	$1,956,820	December 28, 2022	November 30, 2027	STACHLER, MATTHEW D	reporter.nih.gov
Master regulator transcription factors promote esophageal neoplastic evolution	NIH	National Cancer Institute	2022 to 2025	$1,924,436	June 1, 2020	May 31, 2027	LIN, DE-CHEN	reporter.nih.gov
Mechanisms and Targeted Therapy of NRF2-high Esophageal Squamous Cell Carcinoma	NIH	National Cancer Institute	2022 to 2025	$1,858,230	June 1, 2020	December 31, 2025	CHEN, XIAOXIN LUKE	reporter.nih.gov
Validation and Early Commercialization of the ENVISAGE Assay, a Prognostic Test for Barrett's Esophagus	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2023 to 2024	$1,806,319	September 15, 2023	July 31, 2025	LAUN, SARAH	reporter.nih.gov
Point-of-Care Diagnosis of Esophageal Cancer in LMICs	NIH	National Cancer Institute	2023 to 2025	$1,803,699	July 1, 2023	June 30, 2028	MELTZER, STEPHEN J	reporter.nih.gov
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma	NIH	National Cancer Institute	2021 to 2022	$1,795,169	September 26, 2011	April 30, 2023	CHAK, AMITABH	reporter.nih.gov
AI-Assisted Microendoscopy for the Early Detection of Esophageal Cancer	NIH	National Cancer Institute	2023 to 2025	$1,748,861	September 17, 2014	August 31, 2028	ANANDASABAPATHY, SHARMILA	reporter.nih.gov
Multiscale modeling of spatiotemporal evolution in Barrett's esophagus	NIH	National Cancer Institute	2023 to 2025	$1,736,422	September 1, 2023	August 31, 2028	CURTIUS, KATHLEEN M.	reporter.nih.gov
High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader	NIH	National Cancer Institute	2022 to 2025	$1,723,875	January 14, 2022	December 31, 2026	SHI, XIAOBING	reporter.nih.gov
Stratification of Cancer Risk in Patients with Non-Dysplastic Barrett's Esophagus using TissueCypher: The SCRiBE study	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2023 to 2025	$1,715,012	May 1, 2023	April 30, 2027	SOUZA, RHONDA F	reporter.nih.gov
Cytoprotective pathways in esophageal squamous epithelia	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2023 to 2025	$1,673,359	July 15, 2023	May 31, 2027	KATZ, JONATHAN P	reporter.nih.gov
Plastic States Associated with Cellular Stress and Malignancy: Insights for Prevention and Treatment of Lethal Metaplastic Cancers	NIH	National Cancer Institute	2021 to 2022	$1,667,061	January 19, 2016	December 31, 2023	TLSTY, THEA D	reporter.nih.gov
The Oral Microbiome for the Detection of Barretts Esophagus	NIH	National Cancer Institute	2021 to 2023	$1,644,421	June 1, 2019	May 31, 2025	ABRAMS, JULIAN	reporter.nih.gov
A Clinical Trial of Cancer Prevention by Biomarker Based Detections of Barrett's Esophagus and Its Progression	NIH	National Cancer Institute	2025	$1,623,261	January 3, 2025	December 31, 2029	MARKOWITZ, SANFORD D.	reporter.nih.gov
The Role of the Microenvironment in Barrett's Esophagus	NIH	National Cancer Institute	2021 to 2022	$1,587,381	May 1, 2022	October 31, 2023	ABRAMS, JULIAN	reporter.nih.gov
Academic-Industrial Partnership for Barrett's Esophagus Detection and Risk Assessment	NIH	National Cancer Institute	2024 to 2025	$1,543,973	March 1, 2024	February 28, 2029	MELTZER, STEPHEN J	reporter.nih.gov
Academic-Industrial Partnership for Non-invasive Barrett's Esophagus Detection	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$1,495,504	August 1, 2018	July 31, 2024	MELTZER, STEPHEN J	reporter.nih.gov
Minimally Invasive Molecular Approaches for the Detection of Barrett’s Esophagus and Esophageal Adenocarcinoma	NIH	National Cancer Institute	2021 to 2024	$1,473,886	July 2, 2019	June 30, 2025	IYER, PRASAD G.	reporter.nih.gov
Early Targets in Progression of Barrett's Esophagus to Esophageal Adenocarcinoma	NIH	National Cancer Institute	2021 to 2022	$1,448,230	May 1, 2022	April 23, 2023	WANG, THOMAS D	reporter.nih.gov
Mechanisms of cancer mutations	NIH	National Cancer Institute	2023 to 2025	$1,423,519	December 1, 2022	November 30, 2027	PFEIFER, GERD P	reporter.nih.gov
Targeting FGFR Alterations in Gastroesophageal Cancer	NIH	National Cancer Institute	2024 to 2025	$1,396,846	July 15, 2024	June 30, 2029	RYEOM, SANDRA	reporter.nih.gov
Modeling Neoplastic Progression in Barrett's Esophagus - Renewal -2	NIH	National Cancer Institute	2023 to 2025	$1,367,534	February 7, 2023	January 31, 2028	MALEY, CARLO	reporter.nih.gov
CD 1530, an RAR Gamma Agonist for Oral Cavity Squamous Cell Carcinoma Prevention	NIH	National Cancer Institute	2023 to 2025	$1,348,818	September 11, 2023	August 31, 2028	GUDAS, LORRAINE J	reporter.nih.gov
Translational Science of Gastrointestinal Cancer Initiation and Progression	NIH	National Cancer Institute	2021 to 2025	$1,289,608	September 19, 2018	August 31, 2028	YU, MING	reporter.nih.gov
Ultrabright Theranostic SERRS Nanoparticles for Gastrointestinal Endoscopy	NIH	National Cancer Institute	2022 to 2023	$1,275,697	February 1, 2018	May 31, 2025	ROGALLA, STEPHAN	reporter.nih.gov
Pathogenic Germline Mutations in Barrett's Esophagus	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2024 to 2025	$1,242,775	August 15, 2024	May 31, 2029	GALA, MANISH	reporter.nih.gov
Empower treatment effects evaluation of randomized clinical trials for elderly patients with integrated real-world data	NIH	National Institute on Aging	2021 to 2023	$1,156,714	May 1, 2020	April 30, 2025	YANG, SHU	reporter.nih.gov
Single-cell mitochondrial mutation lineage tracing of non-dysplastic and dysplastic Barrett's esophagus	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2024 to 2025	$1,146,914	August 1, 2024	May 31, 2028	SHAFFER, SYDNEY	reporter.nih.gov
Esophageal Squamous Cell Cancer Initiation and Immune Landscape Remodeling	NIH	National Cancer Institute	2024 to 2025	$1,144,052	December 29, 2023	November 30, 2028	PARK, JAE-IL	reporter.nih.gov
Clonal Reconstruction and Targeting of the Correa Sequence	NIH	National Cancer Institute	2021 to 2023	$1,101,644	July 19, 2019	December 31, 2024	MCKEON, FRANK D.	reporter.nih.gov
Gene therapy for GERD-associated esophageal epithelial barrier dysfunction	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$1,061,363	April 15, 2020	March 31, 2024	DEAN, DAVID A	reporter.nih.gov
R01EB025247: Development and Validation of a Virtual Laparoscopic Hiatal Hernia Simulator (VLaHHS)	NIH	National Institute of Biomedical Imaging and Bioengineering	2021 to 2023	$1,051,049	July 1, 2021	June 30, 2025	SANKARANARAYANAN, GANESH	reporter.nih.gov
The role of gastrin in esophageal submucosal gland acinar ductal metaplasia	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$988,604	September 1, 2018	June 30, 2024	GARMAN, KATHERINE	reporter.nih.gov
Common Stem Cell of Origin for Junctional and Gastric Adenocarcinoma	NIH	National Cancer Institute	2025	$949,184	September 15, 2022	August 31, 2027	MCKEON, FRANK D.	reporter.nih.gov
Facile screening for esophageal cancer in LMICs	NIH	National Cancer Institute	2021	$936,336	May 1, 2017	August 31, 2024	MELTZER, STEPHEN J	reporter.nih.gov
Comprehensive minimal residual disease tracking in cancer	NIH	National Cancer Institute	2024 to 2025	$908,380	June 1, 2018	November 30, 2026	MAKRIGIORGOS, G. MIKE	reporter.nih.gov
An accurate, affordable, and transferable assay for minimally invasive detection of esophageal squamous cell carcinoma (ESCC) in Africa and the United States	NIH	National Cancer Institute	2024	$885,000	September 21, 2021	August 31, 2026	LAUN, SARAH	reporter.nih.gov
Signaling Mechanisms Promoting Barrett’s Metaplasia	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$867,515	May 20, 2019	February 29, 2024	QUE, JIANWEN	reporter.nih.gov
Mechanisms and Targeted Therapy of NRF2-high Esophageal Squamous Cell Carcinoma	NIH	National Cancer Institute	2021 to 2022	$862,000	June 1, 2020	December 31, 2022	CHEN, XIAOXIN LUKE	reporter.nih.gov
Improving Diagnosis in Gastrointestinal Cancer: Integrating Prediction Models into Routine Clinical Care	NIH	National Cancer Institute	2023 to 2025	$829,581	July 1, 2023	June 30, 2027	READ, ANDREW J	reporter.nih.gov
Development and Validation of an Automated Algorithm for Real-time Detection of Neoplasia in Barrett's Esophagus using a Low-cost, Portable Microendoscope	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2022 to 2025	$794,861	April 18, 2022	March 31, 2027	TAN, MIMI CHANG	reporter.nih.gov
Genetic susceptibility to Barrett's esophagus: From GWAS to biology	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2022	$762,225	December 21, 2021	June 30, 2022	BUAS, MATTHEW FRANK	reporter.nih.gov
Computational 3D pathology for Barrett's esophagus risk stratification	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2024	$752,672	May 15, 2024	April 30, 2029	LIU, JONATHAN T.C.	reporter.nih.gov
Alcohol metabolism and disease risk in Asians: Examining the impact of personalized phenotypic/genotypic feedback on early drinking trajectories	NIH	National Institute on Alcohol Abuse and Alcoholism	2025	$746,544	September 10, 2025	August 31, 2030	LUCZAK, SUSAN E.	reporter.nih.gov
KLF4 and WNT5A in esophageal epithelial differentiation and stratification	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$730,969	April 1, 2019	March 31, 2023	KATZ, JONATHAN P	reporter.nih.gov
Computational 3D pathology for Barrett's esophagus risk stratification	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2025	$719,169	May 1, 2025	April 30, 2029	LIU, JONATHAN T.C.	reporter.nih.gov
Molecular Mechanisms of Epithelial Contribution to Esophageal Inflammation and Tissue Repair	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021 to 2022	$711,000	April 1, 2018	February 29, 2024	TETREAULT, MARIE-PIER	reporter.nih.gov
The role of NRF2 in reflux-induced esophageal adenocarcinomas	NIH	National Cancer Institute	2021 to 2022	$695,242	February 1, 2018	January 31, 2024	EL-RIFAI, WAEL	reporter.nih.gov
Minimally Invasive Molecular Approaches for the Detection of Barrett’s Esophagus and Esophageal Adenocarcinoma	NIH	National Cancer Institute	2025	$678,428	July 2, 2019	July 31, 2030	IYER, PRASAD G.	reporter.nih.gov
Omniview tethered capsule for low cost, non-endoscopic Barrett's esophagus screening in unsedated patients	NIH	National Cancer Institute	2021 to 2022	$671,199	July 6, 2020	June 30, 2024	FUJIMOTO, JAMES G	reporter.nih.gov
Mechanism of Transcription-coupled DNA Repair and its Impact on Cancer Mutations	NIH	National Cancer Institute	2024 to 2025	$600,321	April 4, 2023	August 31, 2028	MAO, PENG	reporter.nih.gov
Novel Molecular Functions of WEE1 in Esophageal Adenocarcinoma	NIH	National Cancer Institute	2021 to 2023	$574,776	August 1, 2021	July 31, 2024	CHEN, ZHENG	reporter.nih.gov
Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer	NIH	National Cancer Institute	2021	$566,213	April 1, 2020	December 31, 2021	BOEHM, JESSE SAMUEL	reporter.nih.gov
Advanced a/LCI systems for improved clinical utility	NIH	National Cancer Institute	2021	$553,002	December 13, 2016	November 30, 2022	WAX, ADAM	reporter.nih.gov
Barrett's Esophagus Translational Research Network Coordinating Center (BETRNetCC)	NIH	National Cancer Institute	2021 to 2022	$541,680	April 8, 2022	August 31, 2022	SHYR, YU	reporter.nih.gov
PHASE I -TOPIC 431 - DRUG DELIVERY BY ENDOESOPHAGEAL LAVAGE (EEL) TO TREAT ESOPHAGEAL CANCER	NIH	National Cancer Institute	2022 to 2023	$455,000	September 15, 2022	September 14, 2023	BRIAN, CRAIG	reporter.nih.gov
The role of esophageal myofibroblasts in alcohol related esophageal squamous cell carcinoma.	NIH	National Institute on Alcohol Abuse and Alcoholism	2021 to 2022	$433,126	March 15, 2021	February 29, 2024	SHAKER, ANISA	reporter.nih.gov
RNF128 Regulation of TP53 in Barrett's Progression	NIH	National Cancer Institute	2021	$422,751	August 31, 2017	July 31, 2024	RAY, DIPANKAR	reporter.nih.gov
Advanced Development of Patient Ascites Therapeutic Response Biosensors	NIH	National Cancer Institute	2025	$419,133	March 1, 2025	February 29, 2028	BOEHM, JESSE SAMUEL	reporter.nih.gov
Biomarkers for Reducing Mortality of Cancers of the Colon and Esophagus	NIH	National Cancer Institute	2021	$407,598	August 25, 2010	September 30, 2022	MARKOWITZ, SANFORD D.	reporter.nih.gov
The microbiome ecosystem of Barrett's esophagus and progression to cancer	NIH	National Cancer Institute	2022 to 2023	$407,287	July 1, 2022	June 30, 2025	PAULSON, THOMAS G	reporter.nih.gov
Low-Cost, Single-Use Trans-Nasal Cryotherapy Device for Low-Resource Settings	NIH	National Cancer Institute	2023	$406,500	September 26, 2023	August 31, 2025	RAHIMZADEH, JASON H	reporter.nih.gov
A biodegradable barrier preventing anastomotic leaks after esophagectomy	NIH	National Cancer Institute	2025	$406,500	September 18, 2025	August 31, 2027	KELLEY, SCOTT	reporter.nih.gov
The impact of exposure to allergic inflammation on esophageal carcinogenesis	NIH	National Cancer Institute	2021 to 2022	$403,839	December 1, 2020	November 30, 2022	WHELAN, KELLY A	reporter.nih.gov
Approaches and Outcomes of Shared Decision-making and Patient Centered Care Delivery in Barrett's Esophagus	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2022 to 2023	$400,702	September 1, 2022	August 15, 2023	ELURI, SWATHI	reporter.nih.gov
Diagnosis of Esophageal Squamous Cell Carcinoma in Low-Income Countries	NIH	National Cancer Institute	2021	$399,995	September 21, 2021	September 27, 2023	LUNZ, DANIEL GREGORY	reporter.nih.gov
A Novel Radiometry‐Guided Ablation Catheter to Reliably Treat Barrett's Esophagus	NIH	National Cancer Institute	2021	$399,834	September 22, 2021	May 31, 2023	DESAI, SOHAIL	reporter.nih.gov
Approaches and Outcomes of Shared Decision-making and Patient Centered Care Delivery in Barrett's Esophagus	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2024 to 2025	$399,159	September 1, 2022	May 31, 2027	ELURI, SWATHI	reporter.nih.gov
SBIR Topic 463: Clinical evaluation for early detection of esophageal cancer with a novel fluorescence endoscope and pegulicianine, a novel fluorescent probe	NIH	National Cancer Institute	2024	$399,036	September 16, 2024	September 15, 2025	FERRER, JORGE	reporter.nih.gov
Development of a highly sensitive DNA hypermethylation-based kit to identify Barrett's esophagus patients at high risk of progressing to esophageal adenocarcinoma	NIH	National Cancer Institute	2024	$398,738	September 4, 2024	August 31, 2025	ZHOU, ZHONGREN	reporter.nih.gov
Mitigating Physical Function Decline in Older Adults with Gastroesophageal Cancer	NIH	National Institute on Aging	2025	$393,750	September 22, 2025	August 31, 2027	JI, JINGRAN	reporter.nih.gov
Master regulator transcription factors promote esophageal neoplastic evolution	NIH	National Cancer Institute	2021	$380,154	June 1, 2020	December 31, 2021	LIN, DE-CHEN	reporter.nih.gov
Development of diagnostic and prognostic tests for esophageal adenocarcinoma	NIH	National Cancer Institute	2021 to 2022	$374,895	December 16, 2016	November 30, 2023	GODFREY, TONY E	reporter.nih.gov
Mechanism of Transcription-coupled DNA Repair and its Impact on Cancer Mutations	NIH	National Cancer Institute	2023 to 2024	$372,897	April 4, 2023	August 20, 2024	MAO, PENG	reporter.nih.gov
SBIR INNOVATIVE CONCEPT AWARD - DETECTION, DIAGNOSIS, TREATMENT, PREVENTION AND RESEARCH OF PEDIATRIC CANCERS AND/OR RARE CANCERS	NIH	National Cancer Institute	2022	$355,000	February 2, 2022	February 1, 2023	HACHEY, STEPHANIE	reporter.nih.gov
The Role of SOX2 and CDX2 in Barrett's Esophagus Development	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2024 to 2025	$326,522	July 1, 2024	April 30, 2029	JIN, RAMON	reporter.nih.gov
Developing Natural Products to Target IL-8 Signaling and Intercept Progression of Barrett’s Esophagus to Esophageal Adenocarcinoma	NIH	National Cancer Institute	2025	$323,226	August 1, 2025	July 31, 2028	KRESTY, LAURA A	reporter.nih.gov
Patient-Matched Stem Cells of the Barrett's-Dysplasia-Adenocarcinoma Sequence	NIH	National Cancer Institute	2021 to 2022	$315,000	April 11, 2022	February 28, 2023	MCKEON, FRANK D.	reporter.nih.gov
The role of AXL-ABL axis in Barrett's carcinogenesis	NIH	National Cancer Institute	2021	$302,666	March 1, 2016	February 28, 2023	BELKHIRI, ABBES	reporter.nih.gov
Mechanistic understanding of role of ATF2 signaling in radiation-induced esophageal cancer	NIH	National Institute of General Medical Sciences	2024 to 2025	$302,334	April 1, 2024	February 29, 2028	PLUTH, JANICE M	reporter.nih.gov
Esophageal squamous cell cancer initiation and immune landscape remodeling	NIH	National Cancer Institute	2024 to 2025	$257,872	September 1, 2024	August 31, 2026	KO, KYUNG PIL	reporter.nih.gov
Utilizing a human stem cell model of the esophagus to understand racial disparities during injury repair	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2025	$248,999	June 22, 2022	December 31, 2027	FERRER TORRES, DAYSHA	reporter.nih.gov
Mitigating High Grade Radiation-Induced Lymphopenia through Pretreatment Autologous Lymphocyte Infusion	NIH	National Cancer Institute	2021	$176,175	September 13, 2019	July 31, 2024	LIN, STEVEN HSESHENG	reporter.nih.gov
Modeling Esophageal Squamous Cell Cancer Initiation	NIH	National Cancer Institute	2021 to 2022	$162,000	March 1, 2021	February 28, 2023	PARK, JAE-IL	reporter.nih.gov
Dynamic BH3 Profiling with Patient Derived Organoids of Esophageal Cancer and Mesothelioma Enable Precision-Based Targeting of the Mitochondrial Apoptotic Pathway	NIH	National Cancer Institute	2021 to 2022	$160,000	August 1, 2021	July 31, 2023	RIPLEY, ROBERT TAYLOR	reporter.nih.gov
Steering the next generation of NCI-sponsored clinical trials in gastroesophageal cancers	NIH	National Cancer Institute	2024 to 2025	$157,902	September 19, 2024	August 31, 2029	KLEMPNER, SAMUEL J	reporter.nih.gov
Regulation of esophageal tumorigenesis by protein adduction	NIH	National Cancer Institute	2024 to 2025	$153,500	January 1, 2024	December 31, 2026	CASPA GOKULAN, RAVINDRAN	reporter.nih.gov
Leveraging tissue-specific regulatory maps and network-assisted analysis to identify novel genetic risk loci for esophageal adenocarcinoma	NIH	National Cancer Institute	2022 to 2023	$152,399	March 3, 2022	February 28, 2025	BUAS, MATTHEW FRANK	reporter.nih.gov
Translational Epigenomics in Gastrointestinal Cancer	NIH	National Cancer Institute	2021	$147,343	September 19, 2018	March 31, 2022	YU, MING	reporter.nih.gov
Polycyclic aromatic hydrocarbons exposure and dietary risk of Esophageal squamous cell carcinoma in Uganda	NIH	Fogarty International Center	2021	$92,989	September 25, 2017	March 31, 2022	OKELLO, SAMSON	reporter.nih.gov
Volumetric mapping of tissue microstructure with OCT for enhanced dysplasia detection	NIH	National Cancer Institute	2021 to 2022	$92,788	September 1, 2021	August 31, 2023	CANNON, TAYLOR MARIE	reporter.nih.gov
Elucidation of mutant p53-medidated mechanisms in promoting metastatic esophageal cancer	NIH	National Cancer Institute	2022 to 2024	$92,745	September 1, 2022	September 2, 2024	EFE, GIZEM	reporter.nih.gov
Early TP53 Mutations and Genomic Doubling as a Novel Path for Barrett's Esophagus Progression	NIH	National Institute of Diabetes and Digestive and Kidney Diseases	2021	$81,567	April 15, 2016	March 31, 2022	STACHLER, MATTHEW D	reporter.nih.gov
Regulation of RNA processing by the novel spliceosomal protein, TTDN1, in development and cancer	NIH	National Cancer Institute	2021 to 2022	$40,496	September 1, 2020	October 31, 2022	TOWNLEY, BRITTANY A	reporter.nih.gov
Understanding eosinophilic esophagitis-mediated inhibition of esophageal cancer	NIH	National Cancer Institute	2025	$36,264	September 1, 2025	August 31, 2027	FULLER, ANNE	reporter.nih.gov
Leveraging tissue-specific regulatory maps and network-assisted analysis to identify novel genetic risk loci for esophageal adenocarcinoma	NIH	National Cancer Institute	2022	$26,350	March 3, 2022	June 30, 2022	BUAS, MATTHEW FRANK	reporter.nih.gov
Contribution of Cellular and Molecular Heterogeneity of Esophageal Epithelium to Health Disparities in Esophageal Cancer	NIH	National Cancer Institute	2024	$1	May 1, 2024	May 28, 2024	REICHENBACH, ZACHARY W	reporter.nih.gov

Organizations

Organization	Place	NIH awards	NIH amount	NSF amount
Columbia University Health Sciences	New York, NY	12	$31.7 million	$0
University of Colorado Denver	Aurora, CO	2	$8.4 million	$0
Case Western Reserve University	Cleveland, OH	4	$7.7 million	$0
University of TX MD Anderson Can CTR	Houston, TX	6	$6.7 million	$0
Sloan-Kettering Inst Can Research	New York, NY	3	$5.9 million	$0
Johns Hopkins University	Baltimore, MD	4	$5.8 million	$0
Fred Hutchinson Cancer Center	Seattle, WA	3	$5.3 million	$0
Mayo Clinic Rochester	Rochester, MN	2	$4.6 million	$0
Arizona State University	Scottsdale, AZ	2	$4.5 million	$0
Coriell Institute for Medical Research	Camden, NJ	2	$4.2 million	$0
University of Houston	Houston, TX	3	$4.2 million	$0
Massachusetts General Hospital	Boston, MA	4	$4.1 million	$0
University of California, San Francisco	San Francisco, CA	3	$3.7 million	$0
University of Pennsylvania	Philadelphia, PA	3	$3.6 million	$0
William Marsh Rice University	Houston, TX	1	$3.2 million	$0
Massachusetts Institute of Technology	Cambridge, MA	3	$3.2 million	$0
Van Andel Research Institute	Grand Rapids, MI	2	$3.1 million	$0
Dana-Farber Cancer Inst	Boston, MA	2	$3.1 million	$0
University of Southern California	Los Angeles, CA	3	$3.1 million	$0
Capsulomics, LLC	Baltimore, MD	3	$3.1 million	$0
University of Michigan at Ann Arbor	Ann Arbor, MI	4	$3 million	$0
Baylor College of Medicine	Houston, TX	3	$2.7 million	$0
Nelson Scientific Labs LLC	Potomac, MD	1	$2.6 million	$0
University of Alabama at Birmingham	Birmingham, AL	1	$2.4 million	$0
Veravanti, Inc.	Redmond, WA	1	$2 million	$0
Stanford University	Stanford, CA	2	$2 million	$0
Stemsynergy Therapeutics, Inc.	Miami, FL	1	$2 million	$0
University of California, San Diego	La Jolla, CA	1	$1.7 million	$0
Baylor Research Institute	Dallas, TX	1	$1.7 million	$0
Duke University	Durham, NC	2	$1.5 million	$0
University of Miami School of Medicine	Coral Gables, FL	3	$1.4 million	$0
Weill Medical Coll of Cornell Univ	New York, NY	1	$1.3 million	$0
North Carolina State University	Raleigh, NC	1	$1.2 million	$0
University of Rochester	Rochester, NY	1	$1.1 million	$0
Ut Southwestern Medical Center	Dallas, TX	1	$1.1 million	$0
Wake Forest University Health Sciences	Winston-Salem, NC	1	$949,184	$0
North Carolina Central University	Durham, NC	1	$862,000	$0
Vanderbilt University Medical Center	Nashville, TN	2	$844,346	$0
Roswell Park Cancer Institute Corp	Buffalo, NY	2	$788,575	$0
University of Washington	Seattle, WA	1	$752,672	$0
Northwestern University at Chicago	Chicago, IL	1	$711,000	$0
Mayo Clinic Arizona	Scottsdale, AZ	1	$678,428	$0
SUNY at Stony Brook	Stony Brook, NY	1	$600,321	$0
Broad Institute, Inc.	Cambridge, MA	1	$566,213	$0
Isola Therapuetics	Minneapolis, MN	1	$455,000	$0
Temple Univ of the Commonwealth	Philadelphia, PA	3	$440,104	$0
Cryoscope Medical	Dumont, NJ	1	$406,500	$0
Safeguard Surgical LLC	Tampa, FL	1	$406,500	$0
Univ of North Carolina Chapel Hill	Chapel Hill, NC	1	$400,702	$0
Symple Surgical, Inc.	Flagstaff, AZ	1	$399,834	$0
Mayo Clinic Jacksonville	Jacksonville, FL	1	$399,159	$0
Lumicell, Inc.	Newton, MA	1	$399,036	$0
Pre-Cancer Diagnosis, LLC	Belle Mead, NJ	1	$398,738	$0
University of California Los Angeles	Los Angeles, CA	1	$393,750	$0
Cedars-Sinai Medical Center	Los Angeles, CA	1	$380,154	$0
Boston University Medical Campus	Boston, MA	1	$374,895	$0
University of New Mexico Health Scis CTR	Albuquerque, NM	1	$372,897	$0
Washington University	Saint Louis, MO	2	$367,018	$0
Immunotarget Therapeutics, Inc.	Irvine, CA	1	$355,000	$0
University of Nevada Las Vegas	Las Vegas, NV	1	$302,334	$0
Fred Hutchinson Cancer Research Center	Seattle, WA	1	$147,343	$0
Mbarara University/science/ Technology	Mbarara	1	$92,989	$0

Funding by fiscal year

Fiscal year	NIH awards	NIH amount	NSF amount
2025	58	$40,028,060	$0
2024	59	$33,941,648	$0
2023	51	$32,028,434	$0
2022	61	$30,712,693	$0
2021	51	$23,382,650	$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunity	Number	Agency	Listing	Closes	Award ceiling	Why it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)	PA-24-254	NIH		July 12, 2027	Not listed	Notice number printed on 4 awards here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)	PAR-27-089	NIH	93.396	November 2, 2026	Not listed	Same assistance listing 93.396 as 24 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)	PAR-27-088	NIH	93.396	November 20, 2026	Not listed	Same assistance listing 93.396 as 24 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)	RFA-OD-24-011	NIH	93.396	December 4, 2026	Not listed	Same assistance listing 93.396 as 24 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)	PAR-24-214	NIH	93.396	January 7, 2027	$375,000	Same assistance listing 93.396 as 24 awards here
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)	PAR-25-221	NIH	93.396	January 7, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)	PAR-27-009	NIH	93.396	January 25, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)	RFA-CA-28-013	NIH	93.396	February 9, 2027	$700,000	Same assistance listing 93.396 as 24 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)	PAR-25-272	NIH	93.396	May 7, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)	PAR-25-279	NIH	93.396	May 7, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)	RFA-CA-28-003	NIH	93.396	June 11, 2027	$600,000	Same assistance listing 93.396 as 24 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)	PA-24-253	NIH	93.396	July 17, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)	PA-25-080	NIH	93.396	September 7, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
Investigator-Focused Award (Parent R35)	PAR-28-037	NIH	93.396	October 4, 2027	Not listed	Same assistance listing 93.396 as 24 awards here
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)	RFA-CA-27-019	NIH	93.396	October 19, 2027	$300,000	Same assistance listing 93.396 as 24 awards here
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)	PA-25-301	NIH	93.396	January 7, 2028	Not listed	Same assistance listing 93.396 as 24 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)	PA-25-304	NIH	93.396	January 7, 2028	Not listed	Same assistance listing 93.396 as 24 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)	PA-25-306	NIH	93.396	January 7, 2028	Not listed	Same assistance listing 93.396 as 24 awards here
Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)	PAR-24-311	NIH	93.396	January 7, 2028	$500,000	Same assistance listing 93.396 as 24 awards here
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)	PAR-25-043	NIH	93.396	January 7, 2028	$500,000	Same assistance listing 93.396 as 24 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.