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Data / Research funding / Epilepsy

Epilepsy: 924 NIH awards ($1B) to 197 organizations

924 NIH awards ($1B) in the NIH spending category Epilepsy, to 197 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 924 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
SCREENING OF INVESTIGATIONAL THERAPEUTICS TO TREAT, MODIFY OR PREVENT EPILEPSY FOR THE NINDS EPILEPSY THERAPY SCREENING PROGRAM (ETSP)NIHNational Institute on Drug Abuse2022 to 2025$20,858,598March 23, 2022December 31, 2025WILCOX, KARENreporter.nih.gov
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$11,668,134September 1, 2022August 31, 2027LEIN, PAMELA Jreporter.nih.gov
Thalamocortical Responsive Neurostimulation for the Treatment of Lennox-Gastaut SyndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,737,772June 1, 2021May 31, 2027MORRELL, MARTHA Jreporter.nih.gov
Thin, High-Density, High-Performance, Depth and Surface Microelectrodes for Diagnosis and Treatment of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,482,559September 1, 2021August 31, 2027DAYEH, SHADIreporter.nih.gov
Ketamine Add-On for Established Status Epilepticus Treatment Trial (KESETT)NIHNational Institute of Neurological Disorders and Stroke2025$9,296,510January 15, 2025December 31, 2026KAPUR, JAIDEEPreporter.nih.gov
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,833,081April 15, 2022March 31, 2027GALANOPOULOU, ARISTEA Sreporter.nih.gov
Pediatric Dose Optimization for Seizures in EMS (PediDOSE)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$7,509,102August 1, 2021November 30, 2023SHAH, MANISH ISHWARreporter.nih.gov
Automated Seizure Detection for Home Seizure Monitoring with Epilog SensorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,268,747May 15, 2021April 30, 2026LEHMKUHLE, MARK J.reporter.nih.gov
Neuronal Ion and Volume Shifts After Acute Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,203,269May 1, 2020April 30, 2028STALEY, KEVIN J.reporter.nih.gov
Pediatric Dose Optimization for Seizures in EMS (PediDOSE)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$5,974,618August 1, 2021November 30, 2026SHAH, MANISH ISHWARreporter.nih.gov
Late-onset Unexplained Epilepsy as a Risk Factor for DementiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$5,883,988September 1, 2023February 28, 2029LAM, ALICE Dreporter.nih.gov
Implantable Neurostimulators for Control of Oscillatory Brain NetworksNIHNational Institute of Mental Health2021 to 2024$5,770,174August 1, 2020May 31, 2026WIDGE, ALIK S.reporter.nih.gov
Thalamic stimulation to prevent impaired consciousness in epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,379,677September 15, 2019August 31, 2025BLUMENFELD, HALreporter.nih.gov
System Wide Operations for Rare Disorders (SWORD)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,227,397September 30, 2009June 30, 2025KIM, HELENreporter.nih.gov
Genetic Determinants of Epilepsy in Murine SystemsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,770,152January 15, 1993July 31, 2026SANDS, TRISTAN Treporter.nih.gov
Multi-site validation of biomarkers and core clinical outcome measures for clinical trial readiness in CDKL5 Deficiency Disorder - SupplementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,693,682February 15, 2021January 31, 2027BENKE, TIMOTHY Areporter.nih.gov
Channelopathy-Associated Epilepsy Research CenterNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,689,712September 30, 2018August 31, 2024GEORGE, ALFRED L.reporter.nih.gov
Development and validation of AAV vectors to manipulate specific neuronal subtypes and circuits involved in epilepsy and psychiatric disorders across mammalian species.NIHNational Institute of Mental Health2023 to 2024$4,681,385August 22, 2019November 30, 2025FISHELL, GORDON Jreporter.nih.gov
Advancing Epilepsy Diagnosis with Flexible, High-Resolution Thin-Film ElectrodesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$4,639,451March 1, 2022August 31, 2026FRIEDMAN, DANIELreporter.nih.gov
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$4,500,566September 30, 2000June 30, 2024MEADOR, KIMFORD Jreporter.nih.gov
A Phase 3 Pivotal Trial of AGB101 to Slow Progression in MCI due to Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$4,440,050September 30, 2018May 31, 2025MOHS, RICHARD CHARLESreporter.nih.gov
Sodium and Calcium Channels: Structure, Function, Neuroplasticity, and DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$4,413,116May 1, 2019April 30, 2025SCOTT, JOHN Dreporter.nih.gov
The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)NIHNational Institute of Neurological Disorders and Stroke2021$4,283,451May 8, 2020November 30, 2022TOGA, ARTHUR Wreporter.nih.gov
Neuronal and Network Mechanisms of Electrocortical StimulationNIHNational Institute of Neurological Disorders and Stroke2023$4,175,793August 15, 2023July 31, 2026SLUTZKY, MARC W.reporter.nih.gov
Investigating the efficacy and mechanistic pathways of saracatinib, a medical countermeasure, in a pediatric rat DFP modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,894,577August 15, 2021July 31, 2027THIPPESWAMY, THIMMASETTAPPAreporter.nih.gov
Clinical Translation of Targeted and Noninvasive Ultrasonic Propofol UncagingNIHNational Institute of Neurological Disorders and Stroke2021$3,833,148January 1, 2021December 31, 2025AIRAN, RAAG Dreporter.nih.gov
Behavioral feedback and rewards for improving functional brain mapping in presurgical pediatric patientsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,698,647September 20, 2022March 31, 2027KING, KEVINreporter.nih.gov
In Vivo Studies of the Epileptic HippocampusNIHNational Institute of Neurological Disorders and Stroke2023$3,630,462August 1, 1994February 28, 2026ENGEL, JEROME NONEreporter.nih.gov
Biomarkers to Predict Outcome from Responsive Brain Stimulation for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,596,185April 1, 2023March 31, 2026DAVIS, KATHRYN ADAMIAKreporter.nih.gov
Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$3,533,213August 1, 2019May 31, 2025TREVATHAN, EDWINreporter.nih.gov
Inhibition of central CO2 chemoreception by seizures: Effects on ventilation, cardiovascular control and postictal recovery of consciousnessNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,420,815September 15, 2019May 31, 2029RICHERSON, GEORGE Breporter.nih.gov
Brain Glycogen-Metabolism,Mechanisms, and Therapeutic PotentialNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,404,071May 15, 2020April 30, 2028GENTRY, MATTHEW S.reporter.nih.gov
Control of Axon Initial Segment in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,380,533April 15, 2021March 31, 2026SOLTESZ, IVANreporter.nih.gov
BRain Aging and Cognition in Epilepsy (BRACE): A longitudinal investigation of vascular, genetic, and biomarker risk profiles in elderly patients with epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,346,371September 1, 2021February 28, 2027MCDONALD, CARRIE Rreporter.nih.gov
Comparative Safety of Seizure Prophylaxis within the Medicare ProgramNIHNational Institute on Aging2021 to 2025$3,302,661September 30, 2021May 31, 2027MOURA, LIDIA MARIA VERAS ROCHA DEreporter.nih.gov
Neonatal Seizure Registry Developmental Functional EValuation (NSR-DEV)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$3,299,442March 15, 2020February 28, 2026GLASS, HANNAH CRANLEYreporter.nih.gov
Multimodal imaging of memory in epilepsy from whole brain networks to local neuronal responses: Implications for surgical decision-makingNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,292,439December 15, 2021November 30, 2026MCDONALD, CARRIE Rreporter.nih.gov
Optimized Intracranial EEG Targeting in Focal Epilepsy based upon Neuroimaging ConnectomicsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,275,399March 1, 2021February 28, 2027DAVIS, KATHRYN ADAMIAKreporter.nih.gov
DIrectional and SCalable (DISC) Microelectrode Array for Speech DecodingNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$3,269,286February 1, 2023January 31, 2027SEYMOUR, JOHN Preporter.nih.gov
Effects of vascular risk factors on risk for dementia and stroke after late-onset epilepsy (EpilepsyCOG)NIHNational Institute on Aging2022 to 2025$3,188,533July 1, 2022March 31, 2027CHOI, HYUNMIreporter.nih.gov
Integration and interoperability of complex data and tissues from the human brainNIHNational Center for Advancing Translational Sciences2023 to 2025$3,131,401September 20, 2023December 31, 2026LOEB, JEFFREY Areporter.nih.gov
Identifying brain networks to predict treatment resistance and post-surgical outcome: An ENIGMA-Epilepsy initiativeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,130,466July 15, 2021June 30, 2027MCDONALD, CARRIE Rreporter.nih.gov
Advancing SUDEP Risk Prediction Using a Multicenter Case-Control ApproachNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,107,895August 15, 2021July 31, 2026DEVINSKY, ORRINreporter.nih.gov
Exercise for Memory Rehabilitation in EpilepsyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,069,743April 10, 2021March 31, 2026ALLENDORFER, JANE Breporter.nih.gov
Targeting Pathologic Spike-Ripples to Isolate and Disrupt Epileptic DynamicsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,039,937January 1, 2021June 30, 2025CHU, CATHERINE Jreporter.nih.gov
Rapid Point-of-Care Assay for Diagnosis of Neurocysticercosis in Seizure PatientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,999,008May 1, 2025April 30, 2027LEVIN, ANDREW E.reporter.nih.gov
Antiglutamatergic Therapy to Protect the Brain Against Nerve AgentsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,969,523September 1, 2022August 31, 2027BRAGA, MARIA F.reporter.nih.gov
Childhood Status Epilepticus and Epilepsy Determinants of Outcome (SEED) – EEG and MRI SupplementNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,963,176August 1, 2020April 30, 2026TREVATHAN, EDWINreporter.nih.gov
Development of a novel anti-neuroinflammatory experimental therapeutic for epilepsy and Alzheimer's riskNIHNational Institute on Aging2021 to 2025$2,958,817September 1, 2021November 30, 2026SHIFRIN, VICTORreporter.nih.gov
Defining disease mechanisms in SLC35A2 epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,951,492July 1, 2020April 30, 2025HEINZEN, ERIN Lreporter.nih.gov
Novel pediatric anticonvulsants for nerve agentsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,949,509September 1, 2020August 31, 2025REDDY, DOODIPALA SAMBAreporter.nih.gov
Neonatal EEG MOnitor (NEMO) Phase IIbNIHNational Institute of Mental Health2023 to 2025$2,926,931August 15, 2012August 31, 2027MCDONALD, NEIL Jreporter.nih.gov
Blood-Brain Barrier Repair in Alzheimer’s Disease with EpilepsyNIHNational Institute on Aging2022 to 2025$2,905,702May 1, 2022April 30, 2027HARTZ, ANIKA M.S.reporter.nih.gov
Elucidating the molecular mechanisms behind human neurodevelopmental disorders using brain organoidsNIHNational Institute of Mental Health2022 to 2025$2,876,812February 16, 2022December 31, 2026NOVITCH, BENNETT Greporter.nih.gov
Prevention of SUDEP by milk whey: Role of CO2 chemoreception and serotoninNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,860,774August 1, 2021May 31, 2026RICHERSON, GEORGE Breporter.nih.gov
Roles of TREM2 and TYROBP in AD-related Network HyperexcitabilityNIHNational Institute on Aging2023$2,833,089September 1, 2023August 31, 2026MUCKE, LENNARTreporter.nih.gov
Secondarily generalized tonic clonic seizure: a functional anatomyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,810,600September 1, 2021August 31, 2028KAPUR, JAIDEEPreporter.nih.gov
Guiding epilepsy surgery using network models and Stereo EEGNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,801,678June 1, 2022May 31, 2027LITT, BRIANreporter.nih.gov
Seizure-induced enhancement of synaptic signaling regulating tau transmissibility in Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$2,793,375May 1, 2022April 30, 2027JENSEN, FRANCES Ereporter.nih.gov
Circuits Driving Spatial Coding Deficits in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,769,311February 1, 2021December 31, 2025SHUMAN, TRISTANreporter.nih.gov
Exploring the role of ATP1A3 mutations in sudden unexplained death in epilepsyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,764,922August 22, 2022June 30, 2027LANDSTROM, ANDREW P.reporter.nih.gov
Focal Thalamocortical Circuit Dysfunction Mediates Motor and Cognitive Deficits in Developmental EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,734,773May 15, 2020February 28, 2026CHU, CATHERINE Jreporter.nih.gov
Brain Glycogen - Metabolism, Mechanisms, and Therapeutic PotentialNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$2,726,725May 15, 2020August 12, 2022GENTRY, MATTHEW S.reporter.nih.gov
Using Brain Lesions and Deep Brain Stimulation to Identify an Epilepsy CircuitNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,705,167July 1, 2022March 31, 2027FOX, MICHAEL Dreporter.nih.gov
Dissecting the Cognitive Roles of Hippocampus and Other Temporal Lobe Structures in Patients Undergoing Epilepsy SurgeryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,678,557July 1, 2014April 30, 2026DRANE, DANIEL Lreporter.nih.gov
4D Transcranial Acoustoelectric Imaging for High Resolution Functional Mapping of Neuronal CurrentsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,677,149September 30, 2020June 30, 2025WITTE, RUSSELL Sreporter.nih.gov
Pathomechanisms of SCN3A-related neurodevelopmental disorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,674,943December 1, 2020November 30, 2026GOLDBERG, ETHAN Mreporter.nih.gov
Seizures and Children's Outcomes after Stroke (SCOUTS)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,672,011January 1, 2022December 31, 2026FOX, CHRISTINE K.reporter.nih.gov
NSR-GENE (Neonatal Seizure Registry, GEnetics of post-Neonatal Epilepsy)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,671,951March 1, 2022February 28, 2027GLASS, HANNAH CRANLEYreporter.nih.gov
Epilepsy in Uganda: Clinical characterization and co-morbidities, their relation to stigma among adolescents and impact of a community-based engagement program (AWE Change project)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,657,526September 17, 2021August 31, 2026KAKOOZA, ANGELINA MWESIGEreporter.nih.gov
Personalized Seizure Forecasting: A Precision Medicine ApproachNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,642,096July 1, 2024June 30, 2029ZAVERI, HITTEN Preporter.nih.gov
Intracranial Investigation of Neural Circuity Underlying Human MoodNIHNational Institute of Mental Health2023 to 2025$2,628,706June 1, 2023March 31, 2028SHETH, SAMEER ANILreporter.nih.gov
The STAT3 Response of Excitatory Neurons to Epileptogenic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,626,359May 1, 2022April 30, 2027RUSSEK, SHELLEY Jreporter.nih.gov
Molecular, Cellular and Behavioral Impact of the R203W PACS1 Syndrome MutationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,596,944May 1, 2022March 31, 2027THOMAS, GARYreporter.nih.gov
A Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,592,382September 21, 2021August 31, 2027BANSAL, PRANAVreporter.nih.gov
An Interneuron-based Cell Therapy for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,589,602September 1, 2010March 31, 2027BARABAN, SCOTT Creporter.nih.gov
Somatic Mutation in Intractable Focal EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,579,156August 15, 2020January 31, 2026WINAWER, MELODIE ROSEreporter.nih.gov
Cell type selective viral tools to interrogate and correct non-human primate and human brain circuitryNIHNational Institute of Mental Health2021 to 2022$2,577,166September 1, 2020February 29, 2024TING, JONATHAN Treporter.nih.gov
Deciphering the Role of the Pumilio1 in Two Distinct Neurological DiseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,563,512June 15, 2019March 31, 2029GENNARINO, VINCENZO ALESSANDROreporter.nih.gov
Neuronal excitability and copy number variation disordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,563,265September 1, 2020May 31, 2026PENZES, PETERreporter.nih.gov
Motor cortex plasticity in temporal lobe epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,543,160April 1, 2021December 31, 2026KAPUR, JAIDEEPreporter.nih.gov
Diagnostic validity and safety of high-gamma language mapping with intracranial EEGNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,530,608June 1, 2020February 28, 2026CRONE, NATHAN Ereporter.nih.gov
Role of the Kinesin KIF1A in Neurological DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,526,535February 15, 2020December 31, 2024VALLEE, RICHARD BERTreporter.nih.gov
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,525,196August 1, 2020July 31, 2026GILMORE, EMILYreporter.nih.gov
Traumatic Brain Injury Anti-Seizure Prophylaxis in the Medicare ProgramNIHNational Institute on Aging2023 to 2025$2,504,051September 15, 2023May 31, 2028MOURA, LIDIA MARIA VERAS ROCHA DEreporter.nih.gov
New Inactivators of GABA Aminotransferase for Epilepsy and Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,498,237July 15, 2021June 30, 2026SILVERMAN, RICHARD Breporter.nih.gov
Characterizing High Frequency Oscillations as an epilepsy biomarker with Big Data toolsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,494,779September 1, 2015January 31, 2027STACEY, WILLIAM CHARLESreporter.nih.gov
Epilepsy Seizure Detection with Innovative Tripolar EEG (tEEG)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,490,741August 1, 2021July 31, 2027BESIO, WALTER GRANTreporter.nih.gov
Ion Channel Pharmacology for Pain and EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,475,651May 1, 2022April 30, 2025BEAN, BRUCE Preporter.nih.gov
Daily Regulation of Ionic CurrentsNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,472,954April 1, 2010May 31, 2026LEDERER, WILLIAM JONATHANreporter.nih.gov
Targeting Microglia in Febrile Status EpilepticusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,437,788August 1, 2021April 30, 2027EYO, UKPONG BASSEYreporter.nih.gov
Control of Seizure and Migraine Susceptibility by GPR37L1NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,433,005July 15, 2021June 30, 2027HALL, RANDY A.reporter.nih.gov
EpiScalp: An EEG Analytics Solution to Improve Diagnosis of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$2,419,710August 13, 2024July 31, 2027GOTSHALK, ANDREWreporter.nih.gov
Mechanisms of Loss, Recovery and Disorders of ConsciousnessNIHNational Institute of General Medical Sciences2021 to 2025$2,413,063February 15, 2014April 30, 2027BANKS, MATTHEW Ireporter.nih.gov
PET/MR Correlates of Accelerated Aging in Chronic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,409,083April 15, 2021December 31, 2026MCMILLAN, ALAN BLAIRreporter.nih.gov
A multicenter, randomized controlled trial of single and multiple dose regimes of oxfendazole for mild (one or two lesions) parenchymal brain cysticercosisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,400,684September 1, 2023May 31, 2028GARCIA, HECTOR HUGOreporter.nih.gov
Progressive seizure-induced cardiorespiratory dysfunction in a novel mutant rat model of seizure disorderNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,400,623April 17, 2015March 31, 2026HODGES, MATTHEW ROBERTreporter.nih.gov
Exploring the role of oxytocin in the regulation of neuronal excitabilityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,392,065May 1, 2021March 31, 2026ESCAYG, ANDREW Preporter.nih.gov
The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognitionNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,379,308April 10, 2020March 31, 2026SUH, HOONKYOreporter.nih.gov
Functional Genetics of the Neuronal Sodium Channel Gene SCN8ANIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,368,240May 1, 1996January 31, 2027MEISLER, MIRIAM Hreporter.nih.gov
Genetics of Epilepsy in Mali (GENEP-Mali)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,356,733August 15, 2021June 30, 2027LANDOURE, GUIDAreporter.nih.gov
The Juvenile Myoclonic Epilepsy Connectome ProjectNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,340,618March 15, 2020January 31, 2026STRUCK, AARON Freporter.nih.gov
Hippobellum: Cerebellar influence on the hippocampus and temporal lobe seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,327,752June 1, 2020February 28, 2030KROOK-MAGNUSON, ESTHERreporter.nih.gov
Neurodevelopmental Disorder-Associated Rho Regulators in Neocortical DevelopmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,326,531April 1, 2020January 31, 2026VAN AELST, LINDAreporter.nih.gov
Contribution of Innate Immune Receptors to Neurological Dysfunction After Traumatic Brain Injury: Mechanisms and Therapeutic ImplicationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,291,943April 1, 2021March 31, 2027SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
Reliable Seizure Prediction Using Physiological Signals and Machine LearningNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,258,893June 1, 2022May 31, 2027WORRELL, GREGORY Areporter.nih.gov
Mitochondrial Mechanisms of Astrogliosis in EpilesyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,256,883December 1, 1999June 30, 2026PATEL, MANISHA Nreporter.nih.gov
Semaphorin-Dependent GABAergic Synapse Formation: A Novel Approach to Increasing Inhibition in the Intact BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,250,925August 1, 2010April 30, 2025PARADIS, SUZANNEreporter.nih.gov
New classes of optogenetic and chemogenetic tools with a feedback controlNIHNational Institute of Mental Health2022 to 2025$2,250,000August 15, 2022August 14, 2027WANG, WENJINGreporter.nih.gov
Novel Therapeutic Strategies to Resolve Neurovascular Inflammation and Repair Blood-Brain Barrier Dysfunction in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,224,507September 30, 2012March 31, 2027BAUER, BJOERNreporter.nih.gov
Alternative Mechanisms of Signaling Via Trimeric G ProteinsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,224,007September 1, 2014March 31, 2026GARCIA-MARCOS, MIKELreporter.nih.gov
TSPO-PET and MRI Imaging as Novel Imaging Tools for Autoimmune EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,221,278May 15, 2022April 30, 2027STERIADE, CLAUDEreporter.nih.gov
Mechanism and role of mTORC2 in seizure reductionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,219,206December 15, 2021November 30, 2026CHIN, JEANNIEreporter.nih.gov
Development and validation of AAV vectors to manipulate specific neuronal subtypes and circuits involved in epilepsy and psychiatric disorders across mammalian species.NIHNational Institute of Mental Health2021$2,208,603August 22, 2019November 30, 2022FISHELL, GORDON Jreporter.nih.gov
Physiological-based Pharmacokinetics Approach to Determine the Extent of Drug Exposure of Antiseizure Medications During Pregnancy and BreastfeedingNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,202,494August 4, 2021May 31, 2027BIRNBAUM, ANGELA Kreporter.nih.gov
Prospective Validation of Neurophysiologic Outcome Prediction in Acute Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,202,008January 1, 2023December 31, 2027WESTOVER, MICHAEL BRANDONreporter.nih.gov
Normal and Pathological Function of the Dentate GyrusNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,198,370September 1, 2012March 31, 2027TAKANO, HAJIMEreporter.nih.gov
CRH Dysregulation of Brainstem Autonomic Circuits Increases SUDEP RiskNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,183,194December 9, 2022November 30, 2027MAGUIRE, JAMIE LYNNreporter.nih.gov
Network based neuro-modulation for mesial temporal lobe epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$2,182,343April 15, 2022March 31, 2028TANDON, NITINreporter.nih.gov
Electrographic Seizure Pattern Modulation Biomarkers in Responsive Neurostimulation for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,179,951June 15, 2023May 31, 2026RICHARDSON, ROBERT MARKreporter.nih.gov
Rewiring the Injured Brain with GABA ProgenitorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,163,757February 15, 2016March 31, 2027HUNT, ROBERT Freporter.nih.gov
A computational phenotyping approach to characterize neurogenetic disordersNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,152,143February 15, 2023March 31, 2028HELBIG, INGOreporter.nih.gov
Role of SCN1B in Inherited EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,149,827February 1, 2011January 31, 2025ISOM, LORI L.reporter.nih.gov
Metabolic Interventions for Sleep, Anesthesia-related Neurocognitive Disorders and Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$2,137,648June 15, 2022February 28, 2027NEHS, CHRISTA JOYreporter.nih.gov
Excitability and Plasticity of Developing Epileptic BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,135,938September 1, 1991May 31, 2027NOEBELS, JEFFREYreporter.nih.gov
Electrophysiological Source Imaging of Partial EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,129,314June 1, 2016March 31, 2027HE, BINreporter.nih.gov
Respiration and Generalized EpilepsiesNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,122,731April 1, 2022January 31, 2027BEENHAKKER, MARKreporter.nih.gov
Novel DWI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,109,747February 1, 2015June 30, 2026JEONG, JEONG-WONreporter.nih.gov
Subgroup delineation in genetic epilepsies and developmental brain disordersNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,107,564February 15, 2023March 31, 2028HELBIG, INGOreporter.nih.gov
Cardiac Mechanisms of Sudden Unexpected Death in EpilepsyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,101,543July 1, 2020June 30, 2025ISOM, LORI L.reporter.nih.gov
Sequence of physiological events during oxygen conserving reflex activation leading to sudden death in epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,096,515December 1, 2020May 31, 2027KOLIATSOS, VASSILIS Ereporter.nih.gov
Human Epilepsy Genetics - Neuronal Migration DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,084,281July 1, 1997November 30, 2024WALSH, CHRISTOPHER A.reporter.nih.gov
Patient Specific Parameter Optimization of Thalamic Stimulation for Treatment of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,078,797September 15, 2022August 31, 2027MCGOVERN, ROBERT Areporter.nih.gov
Exploiting EP2 receptor biology to target seizure-related neuroinflammation selectivelyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,065,313June 1, 2020February 28, 2026VARVEL, NICHOLASreporter.nih.gov
NS-PEACE Neonatal Seizures -Predicting Epilepsy and Assessing Comparative EffectivenessNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,062,096May 1, 2023April 30, 2029GRINSPAN, ZACHARY MICHAELreporter.nih.gov
Digital biomarker for a low cost ambulatory test for early detection of Alzheimer's diseaseNIHNational Institute on Aging2021$2,050,969September 30, 2021August 31, 2024MOSHER, JOHN COMPTONreporter.nih.gov
Retraining and Control Therapy (ReACT): Sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric psychogenic non-epileptic seizures (PNES)NIHNational Institute of Mental Health2023 to 2025$2,036,452July 22, 2021August 31, 2026FOBIAN, AARON Dreporter.nih.gov
ZEBRAFISH MODELS FOR DRAVET SYNDROME RESEARCH AND DISCOVERYNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,025,737April 1, 2016January 31, 2026BARABAN, SCOTT Creporter.nih.gov
Quality Improvement in time to Treatment of Status Epilepticus (QuITT-SE)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,019,908September 20, 2023August 31, 2028OSTENDORF, ADAM P.reporter.nih.gov
An MRI-Guided Steerable Needle to Replace Open Brain Surgery for Epilepsy PatientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,013,213December 15, 2020November 30, 2025BARTH, ERIC JOHNreporter.nih.gov
Extracellular Potassium and Astrocytic Kir4.1 Modulate Interneuron Activity in the Cerebral CortexNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,008,572May 15, 2022April 30, 2027ARMBRUSTER, MORITZreporter.nih.gov
High-resolution Infrared Thermal Imaging (ITI) for Simultaneous Functional Mapping of the Entire Craniotomy in Awake PatientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,005,048December 1, 2020November 30, 2025PARRISH, TODD Breporter.nih.gov
Role of HCN1 Channels in the Function and Malfunction of Parvalbumin Positive InterneuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,000,176July 15, 2021April 30, 2026SIEGELBAUM, STEVEN Areporter.nih.gov
Mechanistically-oriented therapy for a progressive myoclonus epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,998,710April 1, 2022March 31, 2027GOLDBERG, ETHAN Mreporter.nih.gov
Genetic Modifiers of Childhood EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,997,505September 1, 2014December 31, 2025KEARNEY, JENNIFER Areporter.nih.gov
Gluconeogenic control of Dravet SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,994,888June 1, 2020May 31, 2026PATEL, MANISHA Nreporter.nih.gov
Identification and molecular characterization of somatic mutations in MCDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,992,437September 30, 2016May 31, 2028HEINZEN, ERIN Lreporter.nih.gov
Seizure localization for epilepsy surgery using high frequency electrophysiological markersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,990,714March 15, 2021February 28, 2027LOPOUR, BETH ANNreporter.nih.gov
Role of CACHD1 in the development of temporal lobe epilepsy and absence epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,983,105July 15, 2021April 30, 2026PATEL, MANOJ Kreporter.nih.gov
Motion Compensated fMRI for Pre-Surgical Planning in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,981,516May 2, 2023April 30, 2028WARFIELD, SIMON Kreporter.nih.gov
Magnetic Resonance-guided Focused Ultrasound Ablation of the Anterior Thalamus as a Novel Treatment Paradigm for AnxietyNIHNational Institute of Mental Health2022 to 2025$1,980,503March 1, 2022December 31, 2026PHAN, K. LUANreporter.nih.gov
Interneuron axonopathy underlies circuit dysfunction in a mouse model of Dravet syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,968,915April 15, 2019December 31, 2029GOLDBERG, ETHAN Mreporter.nih.gov
Cellular Regulation of Sodium-activated Potassium ChannelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,968,910March 1, 2018November 30, 2027KACZMAREK, LEONARD Kreporter.nih.gov
Javits Award Final Three YearsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,963,930May 1, 2023April 30, 2027WILCOX, KAREN Sreporter.nih.gov
Clinical genetics of drug-resistant epilepsy with focal cortical dysplasiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,963,087April 15, 2021June 30, 2023LAL, DENNISreporter.nih.gov
Anti-epileptogenic role of mTOR activation among hippocampal interneuronsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,956,427December 15, 2021November 30, 2025DANZER, STEVE Creporter.nih.gov
Development and validation of an agent-based model to promote evidence-based control of Taenia solium cysticercosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,947,979July 1, 2019December 31, 2024O'NEAL, SETH Ereporter.nih.gov
Seizure control by electric field controlNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,932,038September 30, 2021June 30, 2026DURAND, DOMINIQUE Mreporter.nih.gov
Neuronal hyperexcitability and seizures in a Scn2a deficient mouse modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,925,875July 15, 2021April 30, 2027YANG, YANGreporter.nih.gov
Genetic and Functional Mechanisms in Citrate Transporter Disorder associated with SLC13A5NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,924,140January 1, 2025May 31, 2026LIU, JUDY SHIH-HWAreporter.nih.gov
Functional brain mapping in pediatric neurosurgeryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,923,935March 1, 2009March 31, 2027ASANO, EISHIreporter.nih.gov
Control of dentate neurogenesis: Shh, mossy cells, activity and seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,918,989September 1, 2007March 31, 2025PLEASURE, SAMUEL JEREMYreporter.nih.gov
3D multifunctional deep brain interface for seizure detection and interventionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,918,926August 1, 2021July 31, 2026JIA, XIAOTINGreporter.nih.gov
IGF::OT::IGF OTHER FUNCTIONS NINDS EPILEPSY THERAPY SCREENING PROGRAMNIHNational Institute on Drug Abuse2021 to 2022$1,916,218September 30, 2016March 22, 2022WILCOX, KARENreporter.nih.gov
A Phase 3 clinical trial of an e-health behavioral intervention to improve executive functioning in adolescents with epilepsyNIHNational Institute of Neurological Disorders and Stroke2025$1,907,458May 1, 2025April 30, 2029MODI, AVANI Creporter.nih.gov
Activity and connectivity of hippocampal newborn neurons underlie alcohol withdrawal-associated syndromesNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,897,725August 15, 2023May 31, 2028SUH, HOONKYOreporter.nih.gov
Brain glucose deficiency: mechanisms and modulationNIHNational Institute of Neurological Disorders and Stroke2024$1,875,099August 1, 2024July 31, 2028PASCUAL, JUAN M.reporter.nih.gov
EEG Biomarkers Derived from Dynamical Network Models Enable Rapid Paths to Accurate Diagnosis and Effective Treatment of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,858,355May 16, 2023April 30, 2031SARMA, SRIDEVI V.reporter.nih.gov
Hyperexcitability in Alzheimer's DiseaseNIHNational Institute on Aging2024$1,853,477September 1, 2024August 31, 2027SCHARFMAN, HELEN Ereporter.nih.gov
Breathing Rescue for SUDEP Prevention (BreatheS)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,840,738July 15, 2023June 30, 2028LACUEY LECUMBERRI, NURIAreporter.nih.gov
HIV-1 Neurotoxicity: Mechanism & Modulation by CannabinoidsNIHNational Institute on Drug Abuse2021 to 2024$1,839,474March 15, 1992February 28, 2026THAYER, STANLEY Areporter.nih.gov
Remote effects of focal hippocampal seizures on neocortical functionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,834,034February 1, 2011November 30, 2026BLUMENFELD, HALreporter.nih.gov
Imaging Epilepsy Sources with Biophysically Constrained Deep Neural NetworksNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,831,535June 15, 2023May 31, 2027HE, BINreporter.nih.gov
Cellular and Neural Network Mechanism of Transcranial Electric StimulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,828,399September 22, 2021August 31, 2026DURAND, DOMINIQUE Mreporter.nih.gov
Treating hyperexcitability in Alzheimer's disease with levetiracetam to improve brain function and cognitionNIHNational Institute on Aging2021 to 2023$1,822,498February 15, 2019November 30, 2025SHAFI, MOUHSINreporter.nih.gov
Biomarkers of SUDEP risk based on brain-heart-lungs network dynamicsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,821,763January 15, 2023December 31, 2028GLASSCOCK, ALBERT Ereporter.nih.gov
Implantable Microarray Probe for Real-Time Glutamate and GABA DetectionNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,806,868September 18, 2023August 31, 2025MOLDOVAN, NICOLAIE ANDREIreporter.nih.gov
Serotonergic circuit mechanisms in postictal recovery and arousalNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,802,247December 1, 2022November 30, 2027BUCHANAN, GORDON Freporter.nih.gov
Relating Vigilance to Connectivity and Neurocognition in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,794,359August 15, 2019May 31, 2026ENGLOT, DARIO Jreporter.nih.gov
Brain glucose deficiency: mechanisms and modulationNIHNational Institute of Neurological Disorders and Stroke2023$1,782,404September 15, 2023February 29, 2024PASCUAL, JUAN M.reporter.nih.gov
Development of aberrant cortical interneuron circuitry in genetic mouse models of absence epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,779,070June 15, 2020March 31, 2026JIANG, XIAOLONGreporter.nih.gov
Interictal High Frequency Oscillations of Epileptogenecity in Pediatric PatientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,776,191July 1, 2019March 31, 2025PAPADELIS, CHRISTOSreporter.nih.gov
Integration of Advanced Diffusion MRI and 3D Histology for Improved Neurosurgical TargetingNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,776,184July 1, 2016May 31, 2028MCNAB, JENNIFER Areporter.nih.gov
Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic PlasticityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,761,885December 1, 2021November 30, 2026PAZ, JEANNE Treporter.nih.gov
Role of inflammasomes in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$1,758,724August 15, 2018April 30, 2024GOLENBOCK, DOUGLAS Treporter.nih.gov
MR Fingerprinting for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,753,171January 15, 2019December 31, 2024MA, DANreporter.nih.gov
Activity-dependent endocannabinoid control in epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,751,643April 1, 2023March 31, 2028SOLTESZ, IVANreporter.nih.gov
The mitochondrial Ca2+ uniporter in the regulation of neural activity and susceptibility to seizuresNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,738,234December 15, 2021November 30, 2026USACHEV, YURIY Mreporter.nih.gov
The Role of Hippocampal area CA2 in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,734,818June 1, 2018May 31, 2028SCHARFMAN, HELEN Ereporter.nih.gov
How microglia sense and regulate neuronal activity in the adult brainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,728,773May 15, 2023April 30, 2031WU, LONG-JUNreporter.nih.gov
Common Data Elements for Meaningful and Generalized Integration of PTE ResearchNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,726,405April 1, 2025March 31, 2026WAGENAAR, JOOST Breporter.nih.gov
Promoting Protein Trafficking with 4-phenylbutyrate to Treat Genetic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,720,363March 1, 2022February 28, 2027KANG, JING-QIONGreporter.nih.gov
Mechanisms of Alcohol WithdrawalNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$1,719,297July 10, 2008June 30, 2025GODWIN, DWAYNE Wreporter.nih.gov
Microcircuits of the Subiculum and EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,715,700September 30, 2018February 28, 2029MACCAFERRI, GIANMARIAreporter.nih.gov
Interneuron-based mechanisms of temporal lobe epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,712,123March 1, 2019February 28, 2025BUCKMASTER, PAUL S.reporter.nih.gov
Targeting IDH mutations to improve seizure control in glioma patientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,711,983August 1, 2020April 30, 2026HORBINSKI, CRAIG MICHAELreporter.nih.gov
Role of brainstem cardiorespiratory neurons in SUDEPNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,710,648February 15, 2022December 31, 2026PATEL, MANOJ Kreporter.nih.gov
The Function of the Cytoplasmic tRNA Repertoire in the Cellular and Molecular Homeostasis of the Mammalian BrainNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,709,379January 15, 2022December 31, 2026ACKERMAN, SUSAN Lreporter.nih.gov
Elucidating pathogenic mechanisms in STRADA-related brain malformation and epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,696,274August 15, 2022June 30, 2027DANG, LOUIS TUONG CHINHreporter.nih.gov
Cell type selective viral tools to interrogate and correct non-human primate and human brain circuitryNIHNational Institute of Mental Health2024 to 2025$1,687,664September 1, 2020February 28, 2026TING, JONATHAN Treporter.nih.gov
Water and chloride movement in neurons during seizure activityNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,686,272September 30, 2020June 30, 2026GLYKYS, JOSEPH C.reporter.nih.gov
Acute Modulation of Stereotyped High Frequency Oscillations with a Closed-Loop Brain Interchange System in Drug Resistant EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,681,478September 1, 2021August 14, 2023INCE, NURI FIRATreporter.nih.gov
Tracking pre-seizure dynamics to predict and control seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,680,855September 30, 2020May 31, 2026HUGUENARD, JOHN Rreporter.nih.gov
Identifying Potential Therapeutic Targets for Abusive Head TraumaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,679,245September 1, 2020August 31, 2025COSTINE-BARTELL, BETH Areporter.nih.gov
NMDAR Mutations & Neurodevelopmental Disorder: from Mechanism to Targeted TherapyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,669,333April 1, 2015March 31, 2027YUAN, HONGJIEreporter.nih.gov
Drosophila and mouse models of PNPO deficiencyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,651,373December 1, 2019November 30, 2024ZHUANG, XIAOXIreporter.nih.gov
Non-Invasive Imaging of Neurological Glycogen Storage DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,648,635April 1, 2022March 31, 2027YADAV, NIRBHAY NARAYANreporter.nih.gov
Dravet Syndrome Anti-Epileptic Control by Targeting GIRK ChannelsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,645,372March 1, 2023December 31, 2027LOGOTHETIS, DIOMEDES E.reporter.nih.gov
Defining Novel Mechanisms of Sudden Death in Dravet Syndrome: Dysregulation of Sodium Channels in the HeartNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,643,814December 1, 2021November 30, 2026RADWANSKI, PRZEMYSLAWreporter.nih.gov
Cytoskeletal pathways of cerebellar dysregulation in neurodevelopmental disordersNIHNational Institute of Mental Health2024 to 2025$1,642,202August 23, 2024June 30, 2029LORENZO, DAMARIS Nreporter.nih.gov
Deciphering brain mosaicism in drug-resistant epilepsy at cellular resolutionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,637,932March 1, 2023December 31, 2027BEDROSIAN, TRACY ANNreporter.nih.gov
Predicting Epilepsy Surgery Outcomes Using Neural Network ArchitectureNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,633,469August 15, 2019May 31, 2025DRANE, DANIEL Lreporter.nih.gov
A phenotypic screen for compounds that differentially affect excitatory and inhibitory neuronal signalingNIHNational Institute of Mental Health2022 to 2023$1,630,701August 8, 2019October 31, 2024RYAN, STEVEN JOHNreporter.nih.gov
IL22 Signaling in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,621,031April 15, 2020December 31, 2025HUANG, YUNFEIreporter.nih.gov
Timing of Neuronal Chloride Uptake for Control of Neonatal SeizureNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,599,910January 1, 2022December 31, 2026DZHALA, VOLODYMYRreporter.nih.gov
Precision models of ARX-associated neurodevelopmental disordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,588,474June 1, 2019May 31, 2025HSIEH, JENNYreporter.nih.gov
Spatiotemporal Mechanisms of Olfactory Processing in the Human BrainNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$1,585,728April 1, 2020March 31, 2025GOTTFRIED, JAY Areporter.nih.gov
A multi-site feasibility clinical trial of Retraining and Control Therapy (ReACT), a mind and body treatment for pediatric functional seizuresNIHNational Center for Complementary & Integrative Health2023 to 2025$1,583,621August 1, 2023July 31, 2026FOBIAN, AARON Dreporter.nih.gov
Disrupted Ciliary Signaling in the Brain Pathology of Tuberous Sclerosis ComplexNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,569,617August 1, 2019September 10, 2022SAHIN, MUSTAFAreporter.nih.gov
Inactivation of the hippocampus by electrical stimulation to preview post-surgical verbal recognition memory deficitsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,555,882February 1, 2023January 31, 2028LEE, BRIANreporter.nih.gov
Impact of Chronic Seizures on Neuropsychiatric Comorbidities in AD-Associated ModelsNIHNational Institute on Aging2021 to 2024$1,555,000September 15, 2020May 31, 2026BARKER-HALISKI, MELISSA LEIGHreporter.nih.gov
MIPS (Microtubule Inner Proteins) function in cilia and basal bodiesNIHNational Institute of General Medical Sciences2021 to 2025$1,554,218May 1, 2018March 31, 2026WINEY, MARKreporter.nih.gov
Demyelination is coupled to neuronal hyperexcitability leading to seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,553,622February 1, 2020January 31, 2026TIWARI-WOODRUFF, SEEMA Kreporter.nih.gov
Bidirectional control of Chd2 haploinsufficiencyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,541,689January 1, 2023December 31, 2027HUNT, ROBERT Freporter.nih.gov
Mechanisms of Interictal Spike GenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,536,905August 1, 2020April 30, 2026LILLIS, KYLE PATRICKreporter.nih.gov
SCN8A encephalopathy: disease mechanisms and treatmentNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,530,148March 1, 2023February 29, 2028ESCAYG, ANDREW Preporter.nih.gov
Glial KCNQ channels.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,527,552May 15, 2022March 31, 2027BIANCHI, LAURAreporter.nih.gov
Therapeutic small molecule modulation of Kv channelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,525,426April 1, 2019July 31, 2030ABBOTT, GEOFFREY Wreporter.nih.gov
Probing the Protective Role of EZH2 in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,521,009August 1, 2019May 31, 2024ROOPRA, AVTAR Sreporter.nih.gov
Longitudinal neuroimaging in Sturge-Weber syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,512,343July 1, 2003February 28, 2026JUHASZ, CSABAreporter.nih.gov
Identifying Electrically Coupled Networks in vitroNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,507,591August 1, 2022April 30, 2027HAAS, JULIE Sreporter.nih.gov
Functional analysis of the microRNA-induced silencing complex in epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,505,719December 1, 2019November 30, 2025GROSS, CHRISTINAreporter.nih.gov
The role of brainstem projecting extended amygdala neurons in sudden unexpected death in epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,503,408September 15, 2023August 31, 2028NOBIS, WILLIAM PAULreporter.nih.gov
Development of a novel, preferring potentiator of GABAA receptor for treatment of epilepsyNIHNational Institute of Neurological Disorders and Stroke2025$1,499,869September 23, 2025August 31, 2027CERNE, ROKreporter.nih.gov
A Phase 3 clinical trial of an e-health behavioral intervention to improve executive functioning in adolescents with epilepsyNIHNational Institute of Neurological Disorders and Stroke2024$1,492,982February 27, 2024January 31, 2025MODI, AVANI Creporter.nih.gov
Prevention of Seizure-Induced Sudden Death by Stimulating Serotonergic SignalingNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,492,890March 1, 2020December 31, 2024FENG, HUAJUNreporter.nih.gov
Implementation of ring strategy for community-engaged control of neurocysticercosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,490,754December 15, 2013December 31, 2024O'NEAL, SETH Ereporter.nih.gov
Basal Ganglia - Brainstem Networks in the Control of SeizuresNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,489,541July 15, 2016April 30, 2028FORCELLI, PATRICK ALEXANDERreporter.nih.gov
The Role of Network Connectivity in Post-Surgical Seizure Recurrence in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,483,852September 30, 2018June 30, 2025MORGAN, VICTORIA Lreporter.nih.gov
Neurotrophins and EpileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,480,014July 15, 2006September 30, 2024MCNAMARA, JAMES O.reporter.nih.gov
Shared Genetics and Risk Factors Between Epilepsy and Psychiatric DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,479,892January 1, 2019April 30, 2024BRENNAND, KRISTEN JENNIFERreporter.nih.gov
Dynamic temporal regulation of astrocyte coupling to shape neuronal activity during acquired epilepsy developmentNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,478,759May 15, 2022February 28, 2027ROBEL, STEFANIEreporter.nih.gov
Mechanisms of altered synaptic integration and plasticity underlying cellular and circuit dysfunction in genetic epilepsy disordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,460,067June 15, 2020March 31, 2026HOWARD, MACKENZIE Areporter.nih.gov
Mossy Cells in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,458,962January 1, 2023December 31, 2025SCHARFMAN, HELEN Ereporter.nih.gov
Epilepsy in Focal Cortical MalformationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,450,581April 1, 2019March 31, 2024BORDEY, ANGELIQUEreporter.nih.gov
Perinatal brain therapeutics: a high throughput biology approach to build next generation RNA precision medicinesNIHNational Institute of Neurological Disorders and Stroke2025$1,440,000August 1, 2025July 31, 2028SMITH, RICHARD Sreporter.nih.gov
Role of Perineuronal Nets in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,439,218May 1, 2021November 30, 2025SONTHEIMER, HARALD Wreporter.nih.gov
Landis Award for Outstanding Mentorship 2025NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,438,971August 1, 2023July 31, 2028HSIEH, JENNYreporter.nih.gov
Identification and reversal of primary and secondary epileptogenic changesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,435,222May 15, 2009March 31, 2025DANZER, STEVE Creporter.nih.gov
Therapeutic Potential and Mechanisms of Tau Reduction in Autism ModelsNIHNational Institute of Mental Health2021 to 2022$1,434,250July 3, 2018April 30, 2024MUCKE, LENNARTreporter.nih.gov
Sourcerer IC: A Web-Based Integrative Multi-Modal Workflow for Epilepsy Surgical PlanningNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,428,087January 1, 2022June 30, 2025LUU, PHANreporter.nih.gov
KPTN Loss and Megalencephaly: mTOR Activation as Therapeutic TargetNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,418,636January 1, 2022December 31, 2025CRINO, PETER Breporter.nih.gov
The neural circuitry of seizure-induced apnea and SUDEPNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,415,574June 1, 2023May 31, 2028WENKER, IAN CHRISTOPHERreporter.nih.gov
Inhibitory Network Plasticity in Neurological DiseaseNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,414,483September 30, 2011May 31, 2029SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
MRI Connectivity Biomarkers of Treatment Response in Focal EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,411,024February 15, 2019January 31, 2026MORGAN, VICTORIA Lreporter.nih.gov
Molecular Mechanisms of Epilepsy-Causing Mutations in IKM channels: anti-epileptic effect of Lipophilic compounds.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,409,055January 1, 2020March 31, 2025BARRO-SORIA, RENEreporter.nih.gov
Neurophysiologically Based Brain State Tracking & Modulation in Focal EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021$1,407,382September 30, 2015June 30, 2024WORRELL, GREGORY Areporter.nih.gov
Structural and functional sequelae of neonatal anticonvulsant exposure: drug-seizure interactionsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,405,887September 1, 2018June 30, 2024FORCELLI, PATRICK ALEXANDERreporter.nih.gov
Gating and Permeation in Ionotropic Glutamate ReceptorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,403,917April 1, 2015March 31, 2026WOLLMUTH, LONNIE Preporter.nih.gov
Inflammatory regulation of epileptogenesis after status epilepticusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,396,500August 3, 2018November 30, 2028JIANG, JIANXIONGreporter.nih.gov
Automated Phenotyping in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,392,018September 30, 2019June 30, 2024SOLTESZ, IVANreporter.nih.gov
Autoresuscitation and SUDEPNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,390,524April 1, 2022January 31, 2027SIMEONE, TIMOTHY A.reporter.nih.gov
Development of multimodal network analyses to improve epilepsy surgery outcomesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,380,472December 6, 2023November 30, 2028ENGLOT, DARIO Jreporter.nih.gov
Understanding the Fast and Slow Spatiotemporal Dynamics of Human SeizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,374,142July 1, 2019March 31, 2025KRAMER, MARK ALANreporter.nih.gov
Molecular and Cellular Basis of Spiking and Seizures in Neocortical EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,372,488July 15, 2019April 30, 2025LOEB, JEFFREY Areporter.nih.gov
Role of mTOR in Circadian and Sleep Deregulation in Smith-Kingsmore Syndrome (SKS)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,371,419February 1, 2023December 31, 2027LIU, ANDREW C.reporter.nih.gov
An informatics framework for SUDEP Risk Marker Identification and Risk AssessmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,368,275May 15, 2020April 30, 2026CUI, LICONGreporter.nih.gov
Retraining and Control Therapy (ReACT): Sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric psychogenic non-epileptic seizures (PNES)NIHNational Institute of Mental Health2021 to 2022$1,364,810July 22, 2021June 30, 2024FOBIAN, AARON Dreporter.nih.gov
Development of Memory Networks in ChildrenNIHNational Institute of Mental Health2022 to 2023$1,350,438June 20, 2016December 31, 2023OFEN, NOAreporter.nih.gov
Fostering medication adherence in children with epilepsy using mHealth technologyNIHNational Institute of Nursing Research2021 to 2022$1,348,847August 1, 2018May 31, 2024MODI, AVANI Creporter.nih.gov
CRCNS: Following the BOLD lightening at rest strikes the seizure onset zone!NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,344,738August 1, 2021July 31, 2026BOERWINKLE, VARINAreporter.nih.gov
Impact of seizure onset pattern on temporal lobe seizure propagation through the basal gangliaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,342,314September 11, 2024July 31, 2029DEVERGNAS, ANNAELLEreporter.nih.gov
Model Development for Prediction of Surgical Outcome in Temporal Lobe Epilepsy Patients: Incorporation of the Correlation between Post-Surgical Reorganization Phenotypes and Pre-Surgical DataNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,337,292July 1, 2019March 31, 2025TRACY, JOSEPH I.reporter.nih.gov
Neuroimaging, neuronal firing and behavior in spike-wave seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,334,078August 15, 2017June 30, 2025BLUMENFELD, HALreporter.nih.gov
AAV Gene Therapy for Sialidosis: from Mice to INDNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,334,051August 1, 2024May 31, 2029GRAY-EDWARDS, HEATHER Lreporter.nih.gov
Optimization of EP2 Antagonists for Post-Seizure Cognitive DeficitsNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,327,964May 1, 2022April 30, 2026GANESH, THOTAreporter.nih.gov
Brain-invading monocytes promote the deleterious consequences of status epilepticusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,320,638December 1, 2019November 30, 2025VARVEL, NICHOLASreporter.nih.gov
Low-frequency stimulation of fiber tracts to control seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,320,282December 1, 2019November 30, 2025DURAND, DOMINIQUE Mreporter.nih.gov
The role of NPRL2 loss in focal cortical dysplasiaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,307,792April 15, 2023March 31, 2028IFFLAND, PHILIP HENRYreporter.nih.gov
Reorganization of visual function in patients with posterior cortical research: Selectivity and plasticityNIHNational Eye Institute2022 to 2025$1,302,978May 1, 2017January 31, 2026BEHRMANN, MARLENEreporter.nih.gov
Functional drug fingerprinting with all-optical electrophysiologyNIHNational Institute of Mental Health2022$1,296,058September 20, 2019June 30, 2023HARWOOD, BENJAMIN NATHANIELreporter.nih.gov
Therapies for Epilepsy Prevention - Focus on AdenosineNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,290,127July 1, 2022June 30, 2027BOISON, DETLEVreporter.nih.gov
Comparative Effectiveness of EEG-Guided Anti-Seizure Treatment in Acute Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,289,414December 1, 2023November 30, 2028ZAFAR, SAHAR Freporter.nih.gov
Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic DietNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,288,567May 15, 2020February 28, 2026HSIAO, ELAINEreporter.nih.gov
Novel presynaptic agents to prevent glutamate-induced neural injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,286,259December 1, 2019November 30, 2025ERICKSON, JEFFREY Dreporter.nih.gov
Motion and Distortion Robust Diffusion Weighted Imaging Sequences for Pediatric PatientsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,283,250January 1, 2022December 31, 2027AFACAN, ONURreporter.nih.gov
Digital biomarker for a low cost ambulatory test for early detection of Alzheimer's diseaseNIHNational Institute on Aging2024 to 2025$1,281,012September 30, 2021August 31, 2027MOSHER, JOHN COMPTONreporter.nih.gov
Precise Prediction and Treatment of Seizures After Intracranial HemorrhageNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,266,671September 1, 2023August 31, 2028NAIDECH, ANDREW Mreporter.nih.gov
Mechanisms of Seizure Resistance in a Mouse Genetic Model with Altered MetabolismNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,258,538March 1, 2018July 31, 2027YELLEN, GARY Ireporter.nih.gov
Dissecting the Developmental and Epileptic Components of Encephalopathy in DEENIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,258,384April 1, 2023June 30, 2025KRISHNAN, VAISHNAVreporter.nih.gov
Development of Culturally Appropriate Spanish Language Tests for Neuropsychological Assessment and Brain MappingNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,255,527January 1, 2024December 31, 2028HAMBERGER, MARLA Jreporter.nih.gov
Cortical development and pathogenesis in DEPDC5-related epilepsiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,252,682September 15, 2019May 31, 2025WANG, YUreporter.nih.gov
MOLECULAR DISSECTION OF SEIZURE MICROENVIRONMENT IN MALIGNANT GLIOMANIHNational Cancer Institute2021 to 2022$1,251,618December 15, 2017November 30, 2023NOEBELS, JEFFREYreporter.nih.gov
Psychosocial Impact of Genetics in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,242,318July 15, 2018November 30, 2024OTTMAN, RUTHreporter.nih.gov
DDALAB: Identifying Latent States from Neural Recordings with Nonlinear Causal AnalysisNIHNational Institute of Mental Health2023$1,240,738May 1, 2023April 30, 2026SEJNOWSKI, TERRENCE Jreporter.nih.gov
Aminu Kano Teaching Hospital-Bayero University Kano-Vanderbilt: Developing Future Leaders in Child Neurology and Epilepsy Research (ABV)NIHFogarty International Center2021 to 2025$1,240,059September 1, 2021July 31, 2026TREVATHAN, EDWINreporter.nih.gov
Closed-Loop Modulation of Hippocampal-Cortical Communication in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,230,419March 15, 2021June 30, 2024GELINAS, JENNIFERreporter.nih.gov
Neuron-specific modulation of gene expression using systemically administered bispecific antibody-ASO conjugatesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,228,078July 1, 2024May 31, 2029THURBER, GREGreporter.nih.gov
Dynamics of long range network interactions in focal epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,221,469September 1, 2013June 30, 2024SCHEVON, CATHERINE Areporter.nih.gov
Scalable and Sensor-Agnostic Software for Distributed Processing and Visualization of Multi-Site MEG/EEG DatasetsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,215,282August 1, 2018February 28, 2023HAMALAINEN, MATTIreporter.nih.gov
The role of UBE3A in gliopathic seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,212,391September 30, 2020August 2, 2024REITER, LAWRENCE Treporter.nih.gov
NMDA receptors and callosal circuitry: development and molecular mechanismsNIHNational Institute of Mental Health2021 to 2023$1,211,250July 1, 2020April 30, 2024PLEASURE, SAMUEL JEREMYreporter.nih.gov
Targeting Alternative Splicing of Sodium Channels to Treat Pediatric Developmental Epileptic EncephalopathiesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,203,280June 1, 2024February 28, 2029OUDIN, MADELEINE JULIEreporter.nih.gov
Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEGNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,202,627February 4, 2022July 31, 2025BRINKMANN, BENJAMIN Hreporter.nih.gov
A flexible, low power, multi-channel, real-time BCI for seizure monitoring and ModulationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,201,913April 1, 2024March 31, 2029MANOHAR, RAJITreporter.nih.gov
Novel diagnostic stimulation to quantify cortical excitability and guide epilepsy therapyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,198,395August 1, 2023July 31, 2028LUNDSTROM, BRIAN NILSreporter.nih.gov
Mechanisms of Memory Enhancement by Deep Brain Stimulation in HumansNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,193,866June 1, 2013August 31, 2025FRIED, ITZHAKreporter.nih.gov
Multiscale modeling and large-scale recordings of trauma-induced epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,190,537September 30, 2018July 31, 2024SEJNOWSKI, TERRENCE Jreporter.nih.gov
Role of deltaFosB in hippocampal gene expression and function in neurological diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,189,218June 15, 2014May 31, 2024CHIN, JEANNIEreporter.nih.gov
Cell Type-Specific Roles of the Na-Activated K Current in KCNT1-Related EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,188,000December 1, 2022November 30, 2027WESTON, MATTHEW Creporter.nih.gov
Urine Screening for Early Detection of Subarachnoid NeurocysticercosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,187,498July 15, 2018December 31, 2024O'NEAL, SETH Ereporter.nih.gov
Uncovering mechanisms and developing novel therapeutic strategies for TBCD-related developmental and epileptic encephalopathyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,186,635February 1, 2024January 31, 2029BRADBURY, ALLISON Mreporter.nih.gov
Acute neural injury and posttraumatic epilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,178,077June 14, 2024April 30, 2029BINDER, DEVIN Kreporter.nih.gov
Development of Memory Networks in ChildrenNIHNational Institute of Mental Health2024 to 2025$1,176,321August 6, 2024May 31, 2027OFEN, NOAreporter.nih.gov
Maladaptive Compensatory Plasticity in Developing Cortical CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,174,762January 1, 2020December 31, 2024NELSON, SACHA Breporter.nih.gov
Functional drug fingerprinting with all-optical electrophysiologyNIHNational Institute of Mental Health2023 to 2024$1,171,510September 20, 2019October 31, 2025HARWOOD, BENJAMIN NATHANIELreporter.nih.gov
Preventing Seizures and Associated Memory Loss in Alzheimer's Disease by Blocking Tau Interactions with SH3-containing Proteins.NIHNational Institute on Aging2021 to 2023$1,170,000September 7, 2020March 31, 2025VOSSEL, KEITH ALANreporter.nih.gov
Cajal-Retzius cells and neuronal signaling in postnatal cortical networksNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,168,992January 15, 2010March 31, 2025MACCAFERRI, GIANMARIAreporter.nih.gov
ClinGen Expert Curation Panel for the EpilepsiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,168,722August 1, 2021July 31, 2025MEFFORD, HEATHER C.reporter.nih.gov
Determining the shared neuronal network mechanisms of focal epileptic discharges and impaired memory processing in temporal lobe epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,165,725June 1, 2023May 31, 2028EWELL, LAURAreporter.nih.gov
Epilepsy Research Training ProgramNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,163,282July 1, 2003June 30, 2029BARAM, TALLIE Z.reporter.nih.gov
Poison exons in epilepsy and neurodevelopmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,161,972June 1, 2024May 31, 2029CARVILL, GEMMA LOUISEreporter.nih.gov
SCH: Neurophysiological AI-Ready Data ResourceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,160,996March 15, 2022February 28, 2026ZHANG, GUO-QIANGreporter.nih.gov
Self-management Intervention for Reducing Epilepsy Burden among Ugandans with EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,160,588August 1, 2023July 31, 2028KADDUMUKASA, MARKreporter.nih.gov
Closed-loop Control of Interneuron Spike Timing in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,156,496March 1, 2024February 28, 2029SHUMAN, TRISTANreporter.nih.gov
Molecular Profiling and Biomarkers of Memory Phenotypes in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,155,956July 15, 2024June 30, 2029BUSCH, ROBYN Mreporter.nih.gov
Drug development for tuberous sclerosis complex and other pediatric epileptogenic diseases using neurovascular and cardiac microphysiological modelsNIHNational Center for Advancing Translational Sciences2021$1,149,180July 21, 2017June 30, 2023WIKSWO, JOHN PETERreporter.nih.gov
Administrative Supplement to Physiology-driven seizure management post-cardiac arrestNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,148,146August 18, 2025December 31, 2026AMORIM, EDILBERTOreporter.nih.gov
Impact of the E209K PACS2 Syndrome mutation on neuronal metabolism and neurotransmission.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,147,552April 17, 2024March 31, 2029THOMAS, GARYreporter.nih.gov
Tracking the evolution of synaptic dysplasticity after early life seizuresNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,144,605March 1, 2024February 28, 2027JENSEN, FRANCES Ereporter.nih.gov
Device-Independent Acquisition and Real Time Spatiotemporal Analysis of Clinical Electrophysiology DataNIHNational Institute of Biomedical Imaging and Bioengineering2021$1,135,742September 15, 2017May 31, 2023PATEL, PADMAVATHI SUNDARAMreporter.nih.gov
Establishing novel properties of dynamic systems models to identify epileptogenic networks in patients with drug resistant epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,129,149February 15, 2022January 31, 2027SARMA, SRIDEVI V.reporter.nih.gov
Modeling seizures in patients with focal epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,124,106September 19, 2023August 31, 2028JUAREZ-COLUNGA, ELIZABETHreporter.nih.gov
Utilizing Human Brain Organoids to Model the Differential Effects of SCN8A Mutation on Cortex and HippocampusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,120,410July 1, 2021June 30, 2026SAMARASINGHE, RANMAL Areporter.nih.gov
The role of Infiltrating Macrophages in Seizure Generation Following CNS InfectionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,117,112August 15, 2021August 31, 2026DE PAULA E SILVA, ANA BEATRIZreporter.nih.gov
Neuronal Circuit Mechanisms of EpileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,117,020May 6, 1999February 29, 2024COULTER, DOUGLAS Areporter.nih.gov
Next generation oncolytic virotherapy targeting AKT and ERK signaling in gliomaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,114,200May 10, 2024April 30, 2029KAUR, BALVEENreporter.nih.gov
Temporal lobe epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,113,033April 15, 2024March 31, 2029BUCKMASTER, PAUL S.reporter.nih.gov
Dynamic changes in PIP2 binding sites and their impact on axonal targeting and function of epilepsy-associated KCNQ/Kv7 channelsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,108,785June 15, 2023May 31, 2028CHUNG, HEE JUNGreporter.nih.gov
Maladaptive Myelination in Pediatric EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,108,665September 1, 2021August 31, 2026KNOWLES, JULIET KLASINGreporter.nih.gov
Developing a Novel E3 Ligase based Anti-inflammatory for ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,102,297February 1, 2022January 31, 2025MALLAMPALLI, RAMA Kreporter.nih.gov
The Contribution of Late Onset Unexplained Epilepsy to Cognitive Decline and its Interaction with Vascular and Alzheimer's Disease PathologiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,098,488September 1, 2021June 30, 2027SARKIS, RANIreporter.nih.gov
AMPA Receptor Ubiquitination and Pathological Synaptic HyperexcitabilityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,091,958April 1, 2018March 31, 2024TSAI, NIEN-PEIreporter.nih.gov
Defining the Epileptogenic Network and Identifying which Components Generate SeizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,085,922September 30, 2018May 31, 2025STABA, RICHARDreporter.nih.gov
The Role of the Endothelial NPYR1-TRPC3-ET1 Signaling Axis in Neurovascular Coupling DysfunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,083,029March 1, 2023February 29, 2028ZHENG, FANGreporter.nih.gov
Decoding the cellular and molecular mechanisms of epileptogenesis and disease progression in mTORopathiesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,080,852July 1, 2024May 31, 2029WANG, YUreporter.nih.gov
Polygenic risk in familial epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,077,570May 1, 2021April 30, 2027ELLIS, COLINreporter.nih.gov
CRCNS: Processing speed in the human connectome across the lifespanNIHNational Institute of Mental Health2021 to 2023$1,075,761September 15, 2019June 30, 2025HERMES, DORAreporter.nih.gov
Identification and optimization of verapamil as a novel neuroprotective and anti-inflammatory agent for reducing long-term neurological morbidities following organophosphate-induced status epilepticusNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,069,767September 1, 2023August 31, 2025DESHPANDE, LAXMIKANT Sreporter.nih.gov
Improved 3D EPI for Pre-Surgical Mapping of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,068,282July 10, 2024May 31, 2029AFACAN, ONURreporter.nih.gov
RECIPROCAL FEEDBACK MECHANISMS OF GLIOBLASTOMA AND NEURONAL NETWORK HYPEREXCITABILITYNIHNational Cancer Institute2023 to 2025$1,061,578March 14, 2023February 29, 2028MEYER, JOCHENreporter.nih.gov
Dissecting the role of gut microbial-derived metabolites on epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,060,158August 1, 2022July 31, 2027CAMPBELL, SUSAN LATOYAreporter.nih.gov
Progesterone receptor regulation of seizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,059,843April 1, 2019March 31, 2026JOSHI, SUCHITRAreporter.nih.gov
The role of CA2 in epilepsy and social comorbidityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,053,670June 1, 2018May 31, 2023SIEGELBAUM, STEVEN Areporter.nih.gov
Molecular Pathways that Strengthen GABAergic Inhibition and Reduce Seizure SusceptibilityNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,051,278July 1, 2024May 31, 2029TANG, XINreporter.nih.gov
Structural and functional investigations on synaptic vesicular transportersNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,046,774March 1, 2024February 28, 2029LEE, CHIA-HSUEHreporter.nih.gov
Na+/Ca2+ exchanger remodeling in alcohol withdrawal seizuresNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,042,875April 15, 2019March 31, 2025N'GOUEMO, PROSPERreporter.nih.gov
CRCNS: US-France-Israel Research Proposal: A personalized approach to brain stimulationNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$1,042,872September 30, 2020June 30, 2026LEE, JIN HYUNGreporter.nih.gov
Novel Glucose dendrimers for targeting injured neuronsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,042,256August 1, 2024June 30, 2029RANGARAMANUJAM, KANNANreporter.nih.gov
Bridging the Treatment Gap by Expanding Access to Care for People with Epilepsy in Kenya (BEACON)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,026,447August 10, 2024July 31, 2029VON GAUDECKER, JANEreporter.nih.gov
The Circadian Molecular Clock is a Biomarker for Epilepsy in Focal Cortical DysplasiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,026,246February 1, 2019January 31, 2024LIU, JUDY SHIH-HWAreporter.nih.gov
Deconstructing Antiseizure Mechanisms of Anterior Thalamic Nucleus Electrical StimulationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,023,090August 20, 2024June 30, 2029GUTEKUNST, CLAIRE-ANNE Nreporter.nih.gov
Cognitive Deficits After Experimental Febrile Seizures: Neurobiology & BiomarkersNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,014,494July 15, 2018April 30, 2024HOLMES, GREGORY L.reporter.nih.gov
Molecular regulators of GABAergic systems that underlie comorbidities in Down syndromeNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,010,880July 1, 2024May 31, 2029YE, BINGreporter.nih.gov
Neuronal Seizure Burden versus Cell Death after Neonatal Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,003,240April 1, 2021March 31, 2027MCNALLY, MELANIE Areporter.nih.gov
Structure and Function of AMPA subtype ionotropic glutamate receptorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,002,257September 30, 2013June 30, 2024SOBOLEVSKY, ALEXANDERreporter.nih.gov
The Role of Microglia in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$996,849May 1, 2014March 26, 2024WU, LONG-JUNreporter.nih.gov
Big Data and Deep Learning for the Interictal-Ictal-Injury ContinuumNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$979,879September 1, 2018September 30, 2022WESTOVER, MICHAEL BRANDONreporter.nih.gov
An Epileptic-Network Closed-loop Stimulation Device (enCLS) Designed to Target and Arrest IctogenesisNIHNational Institute of Neurological Disorders and Stroke2025$975,642August 4, 2025July 31, 2028SUN, HAIreporter.nih.gov
CRCNS: Closed-Loop Computational Neuroscience for Causally Dissecting CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$967,599August 1, 2019May 31, 2025ROZELL, CHRISTOPHER JOHNreporter.nih.gov
Molecular and cellular mechanisms of inhibitory synapse developmentNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$964,632February 15, 2024January 31, 2029ETHELL, IRYNA Mreporter.nih.gov
Predicting Epilepsy in Cerebral Malaria: Working Toward Identifying Biomarkers of Epileptogenesis in ChildrenNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$961,585September 1, 2021December 31, 2025PATEL, ARCHANA A.reporter.nih.gov
Genetic and Cellular Mechanisms of Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$958,466July 15, 2022April 30, 2027KHOSHKHOO, SATTARreporter.nih.gov
NeuroFlex: Wireless, Mechanically Flexible, Stimulation-Capable Depth and Surface High-Density Microelectrode Arrays for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2025$953,287September 10, 2025August 31, 2028YOUNGERMAN, BRETT Ereporter.nih.gov
State-dependent interaction of antiepileptic drugs with voltage-dependent sodium channels and differential regulation of excitatory and inhibitory central neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$949,316February 1, 2019January 31, 2024BEAN, BRUCE Preporter.nih.gov
Quantitative interictal networks to localize seizure generatorsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$934,122December 1, 2021November 30, 2026CONRAD, ERINreporter.nih.gov
Cell Type-Specific Transcriptional Changes Underlying Memory Impairment in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$926,946July 15, 2022June 30, 2027HO, VICTORIAreporter.nih.gov
Amygdala modulation of volitional versus automatic breathingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$925,235December 15, 2020November 30, 2026DLOUHY, BRIAN Jreporter.nih.gov
The role of beta-catenin in the pathophysiology of infantile spasmsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$920,990December 1, 2017November 30, 2022DULLA, CHRIS Greporter.nih.gov
Investigation of Stereotyped High-Frequency Oscillations with Computational Intelligence for the Prediction of Seizure Onset Zone in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$918,463July 15, 2019August 14, 2023INCE, NURI FIRATreporter.nih.gov
Effects of TrkB Activation on Abnormalities in Neocortical FS interneuronNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$918,435April 1, 2013April 30, 2023PRINCE, DAVID ALLANreporter.nih.gov
Prehospital Management of Status EpilepticusNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$918,174April 1, 2020March 31, 2026GUTERMAN, ELANreporter.nih.gov
Mechanisms of Neurodegeneration in a Nerve Agent ModelNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$918,000June 1, 2024May 31, 2027THIPPESWAMY, THIMMASETTAPPAreporter.nih.gov
Novel Water-Soluble Adjunct Anticonvulsants for Nerve AgentsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$894,983September 30, 2020August 31, 2024REDDY, DOODIPALA SAMBAreporter.nih.gov
Somatic Mutations in Neurodevelopment and DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$889,785July 1, 2022April 30, 2027SHAO, DIANE Dreporter.nih.gov
Human Epilepsy Genetics - Mosaic Mutations in Focal EpilepsyNIHNational Institute of Neurological Disorders and Stroke2025$883,490December 1, 1997November 30, 2028WALSH, CHRISTOPHER A.reporter.nih.gov
Speaking of Spikes: Connectivity and Language in Benign Epilepsy with Centrotemporal SpikesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$877,716April 1, 2020March 31, 2025BAUMER, FIONA MITCHELLreporter.nih.gov
VTA VGluT2 Sociability Circuit in Genetic AutismNIHNational Institute of Mental Health2021 to 2022$875,000May 1, 2018September 30, 2024SAPER, CLIFFORD Breporter.nih.gov
Pathophysiology of KCNQ2-related DisordersNIHNational Institute of Neurological Disorders and Stroke2025$874,094August 1, 2025July 31, 2030GEORGE, ALFRED L.reporter.nih.gov
Developing a Zebrafish Model of Slc6a1/GAT1 Hypofunction and an In Vitro Assay to Identify Novel TreatmentsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$870,552July 15, 2020June 30, 2025MCGRAW, CHRISTOPHERreporter.nih.gov
Noninvasive Mapping of Functional and Effective Connectivity in Children with Drug Resistant EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$869,053February 9, 2024November 30, 2028PAPADELIS, CHRISTOSreporter.nih.gov
Uncovering Druggable Allosteric Sites in HCN ChannelsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$864,110March 1, 2024February 28, 2029NIMIGEAN, CRINA Mreporter.nih.gov
Endothelial Vasoprotection by HypothermiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$848,138September 15, 2018June 30, 2024PARFENOVA, HELENAreporter.nih.gov
EpiZode: Noninvasive Seizure Screening in Preclinical Models of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022$843,005April 15, 2018August 31, 2024SUNDERAM, SRIDHARreporter.nih.gov
Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's DiseaseNIHNational Institute on Aging2025$842,175December 15, 2024November 30, 2029ZILBERTER, MISHA YURIreporter.nih.gov
Alpha-Synuclein Induced Network Hyperexcitability in Lewy Body DementiasNIHNational Institute on Aging2021$840,282September 30, 2021August 31, 2023VOSSEL, KEITH ALANreporter.nih.gov
In Vivo Analyses of Kinase Signaling in Learning/Memory CircuitryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$839,153December 1, 2023November 30, 2028BROADIE, KENDALreporter.nih.gov
Small molecule inhibitors of TrkB SignalingNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$836,596September 1, 2023August 31, 2025MCNAMARA, JAMES O.reporter.nih.gov
Mechanisms that determine Glutamine synthetase activity in the brainNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$836,409September 15, 2012June 30, 2024MOSS, STEPHEN Jreporter.nih.gov
Novel Cre-Dependent AAVs with Minimal Off-Target Expression to Study Neural CircuitsNIHNational Institute of Mental Health2024 to 2025$834,528July 1, 2024March 31, 2027PEREZ-REYES, EDWARDreporter.nih.gov
Multi-scale disease modeling of SCN2A-related epilepsy due to gain-of-function variantsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$833,085July 1, 2022April 30, 2027ADNEY, SCOTT K.reporter.nih.gov
Precise, non-invasive, axon-sparing surgery for the treatment of drug resistant epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$823,766May 15, 2018February 28, 2023LEE, KEVIN SCOTTreporter.nih.gov
Cortical Interneuron Transplantation to Treat Intractable Epilepsy.NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$822,598June 1, 2025August 31, 2026CHUNG, SANGMIreporter.nih.gov
Understanding the Etiology of CASK Associated Epileptic EncephalopathyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$815,737April 1, 2021December 9, 2023SRIVASTAVA, SARIKAreporter.nih.gov
electroencephalography and single-unit recordingsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$815,400December 15, 2020November 30, 2025BOLY, MELANIEreporter.nih.gov
Contribution of adult neurogenesis to epileptogenesis and recovery after TBINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$812,923June 1, 2018May 31, 2025SMITH, BRET Nreporter.nih.gov
The function of respiratory-linked local field potential oscillations in human olfactory and limbic brain regionsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2022$808,479May 1, 2018October 31, 2023ZELANO, CHRISTINA MARIAreporter.nih.gov
Maternal epilepsy, antiepileptic drug use during pregnancy, and risk of autismNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$808,032June 1, 2019April 30, 2024LEE, BRIAN KANEreporter.nih.gov
Modeling West Syndrome to Prevent Neurobehavioral DisabilitiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$802,500September 1, 2021August 31, 2024BALLESTER ROSADO, CARLOS Jreporter.nih.gov
Modeling genetic risk for epilepsy using IPSC and animal models.NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$797,040July 1, 2020June 30, 2025HABELA, CHRISTAreporter.nih.gov
Redox Control of Seizure-Induced Neuroinflammation.NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$792,848September 30, 2013June 30, 2024PATEL, MANISHA Nreporter.nih.gov
Cortical Localization in EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$791,572December 1, 1996June 30, 2025HAMBERGER, MARLA Jreporter.nih.gov
Disruption in the network communication of safety in epilepsy with comorbid anxietyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$785,866April 15, 2019February 28, 2023MAGUIRE, JAMIE LYNNreporter.nih.gov
Inhibitors of TrkB SignalingNIHNational Institute of Neurological Disorders and Stroke2021$780,531May 1, 2019April 30, 2024MCNAMARA, JAMES O.reporter.nih.gov
Hippocampal arteriole remodeling and brain injury in preeclampsia and eclampsiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$780,000September 1, 2018May 31, 2024CIPOLLA, MARILYN Jreporter.nih.gov
Synaptic Mechanisms of Continuous Theta Burst Stimulation in DepressionNIHNational Institute of Mental Health2025$777,016July 1, 2025April 30, 2030BROWN, JOSHUA Creporter.nih.gov
Late-onset Epilepsy and CognitionNIHNational Institute on Aging2021 to 2024$774,802August 1, 2020April 30, 2026JOHNSON, EMILYreporter.nih.gov
PCDH19-related Epilepsy-Human Genotype-Phenotype Studies Lead to Zebrafish StudiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$774,376December 1, 2017November 30, 2024PODURI, ANNAPURNAreporter.nih.gov
Cortico-hippocampal circuit dysfunction in an Scn1a mouse model of epilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$774,360July 1, 2022June 30, 2026MATTIS, JOANNA Hreporter.nih.gov
Joint analysis of genomic and electronic medical record data to assess outcomes and drug response in pediatric epilepsiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$770,668March 1, 2020February 28, 2025HELBIG, INGOreporter.nih.gov
Functional genetic basis of KCNB1 encephalopathyNIHNational Institute of Neurological Disorders and Stroke2025$769,995August 1, 2025July 31, 2029KEARNEY, JENNIFER Areporter.nih.gov
Mechanisms of seizure resistance in a mouse genetic model with altered metabolismNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$769,192March 1, 2018November 30, 2023YELLEN, GARY Ireporter.nih.gov
Non-Invasive Seizure Forecasting System Using E-Diaries, Internal and External FactorsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$767,127September 1, 2022May 31, 2027GOLDENHOLZ, DANIEL Mreporter.nih.gov
Etiological Role of Parasitic Exposure and Familial Susceptibility in Nodding Syndrome-Related EpilepsiesNIHFogarty International Center2022 to 2025$765,414September 21, 2022April 30, 2027MAZUMDER, RAJARSHIreporter.nih.gov
Targeting TRPC3 Channels for Epileptic SeizuresNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$765,000December 1, 2021November 30, 2024JIANG, JIANXIONGreporter.nih.gov
Molecular Mechanism of Hippocampal network excitability in a novel, in vivo model of Tuberous Sclerosis ComplexNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$760,121July 15, 2018June 30, 2024RAAB-GRAHAM, KIMBERLY FRANCESreporter.nih.gov
Decoding / encoding somatosensation from the hand area of the human primary somatosensory (S1) cortex for a closed-loop motor / sensory brain-machine interface (BMI)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$758,301July 1, 2020June 30, 2025LEE, BRIANreporter.nih.gov
EEG and MRI Biomarkers to Predict Post-traumatic EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$757,377July 1, 2020June 30, 2025KIM, JENNIFER Areporter.nih.gov
Mechanisms of Cognitive Impairment Following Early-Life SeizuresNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$753,360June 15, 2018May 31, 2023HOLMES, GREGORY L.reporter.nih.gov
Treatment of Lafora disease with an antibody-enzyme fusionNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$751,062December 15, 2019December 31, 2025GENTRY, MATTHEW S.reporter.nih.gov
Mechanisms of PCDH19-clustering epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$745,740January 15, 2023December 31, 2027ZIOBRO, JULIE Mreporter.nih.gov
Mechanisms of focal epileptogenesis in mTORopathiesNIHNational Institute of Neurological Disorders and Stroke2025$743,776September 11, 2025August 31, 2033DANZER, STEVE Creporter.nih.gov
Functional Alterations of Parvalbumin Interneurons Contributing to Abnormal Network Activity in Alzheimer's Disease Mouse ModelsNIHNational Institute on Aging2023 to 2025$742,002April 15, 2023January 31, 2027MA, KERANreporter.nih.gov
Characterizing Population Differences between Clinical Trial and Real World PopulationsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$739,530June 15, 2023May 31, 2026BEAULIEU-JONES, BRETT Kreporter.nih.gov
Noninvasive Optogenetic Interventions for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$739,001May 1, 2021July 31, 2026CHEN, RITCHIEreporter.nih.gov
The gut brain axis: microbial impact on neural functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$732,812June 1, 2018February 28, 2023ALKEMA, MARKreporter.nih.gov
Network analysis for epilepsy surgeryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$732,812July 1, 2019March 31, 2024ZAVERI, HITTEN Preporter.nih.gov
A Nomogram to Predict Seizure Outcomes after Resective Epilepsy SurgeryNIHNational Institute of Neurological Disorders and Stroke2021$728,061May 15, 2017April 30, 2023JEHI, LARAreporter.nih.gov
Understanding the Etiology of CASK Associated Epileptic EncephalopathyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$727,855April 1, 2021December 31, 2026SRIVASTAVA, SARIKAreporter.nih.gov
Development and Validation of a Transgenic Rabbit Model of Dravet SyndromeNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$726,223February 1, 2023January 31, 2025ISOM, LORI L.reporter.nih.gov
Refining neurophysiological biomarkers of epilepsy using deep learning to guide pediatric epilepsy surgeryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$726,165April 1, 2023March 31, 2028NARIAI, HIROKIreporter.nih.gov
New approach for identification pHFO networks to predict epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$720,100July 15, 2022June 30, 2027LI, LINreporter.nih.gov
Neural and pituitary mechanisms linking epilepsy to co-morbid reproductive endocrine dysfunctionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$719,549April 1, 2018March 31, 2024CHRISTIAN-HINMAN, CATHERINE Areporter.nih.gov
Neurological pathophysiology of disrupted O-glycosylation in congenital disorders of glycosylationNIHNational Institute of Neurological Disorders and Stroke2025$719,498August 1, 2025July 31, 2030EDMONDSON, ANDREW CHARLESreporter.nih.gov
Multi-Scale Cortical Dynamics in Human EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$717,656July 1, 2012October 31, 2024TRUCCOLO, WILSONreporter.nih.gov
Perisomatic inhibition in epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$714,631July 15, 2020March 31, 2027DUDOK, BARNAreporter.nih.gov
Understanding the role of SCN8A in developmental and epileptic encephalopathyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$710,936February 21, 2024January 31, 2029WAGNON, JACY LEEreporter.nih.gov
Clinical genetics of drug-resistant epilepsy with focal cortical dysplasiaNIHNational Institute of Neurological Disorders and Stroke2024$709,856April 15, 2021March 31, 2026LAL, DENNISreporter.nih.gov
Testing the effects of a selective calpain-2 inhibitor on spontaneous recurrent seizures in mouse models of epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$706,597September 1, 2023May 31, 2026BAUDRY, MICHELreporter.nih.gov
Pathogenesis of epilepsy in a SCN8A human mutation mouse modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$706,562January 1, 2018December 31, 2023PATEL, MANOJ Kreporter.nih.gov
Developmental Pathophysiology in Neocortex Caused By Somatic MutationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$704,376May 1, 2018February 28, 2025LOTURCO, JOSEPH Jreporter.nih.gov
The role of oxidative stress and inflammation in epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$704,376May 15, 2018March 31, 2025TALOS, DELIAreporter.nih.gov
Treatment of status epilepticus and refractory status epilepticus with intravenous topiramate.NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$702,512September 21, 2023August 31, 2025KLEIN, PAVELreporter.nih.gov
Development of a Genetic Rabbit Model of Kcnh2-Mediated Epilepsy, SUDEP, & Long QT Syndrome Type 2NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$702,491September 1, 2023February 28, 2025AUERBACH, DAVID SCOTTreporter.nih.gov
Gene Therapy for Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$701,745June 1, 2024May 31, 2026ROTENBERG, ALEXANDERreporter.nih.gov
Network Pharmacology for Epilepsy PreventionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$700,003September 22, 2021August 31, 2024KLEIN, PAVELreporter.nih.gov
Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEGNIHNational Institute of Neurological Disorders and Stroke2025$699,582February 4, 2022July 31, 2028BRINKMANN, BENJAMIN Hreporter.nih.gov
Plug-and-Play High-Order B0 Shimming for Reliable Temporal Lobe Epilepsy Magnetic Resonance Spectroscopic ImagingNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$699,262September 22, 2021August 31, 2024YANG, HSIN-JUNGreporter.nih.gov
Thalamocortical interactions and the effect of thalamic stimulation on sleep oscillationsNIHNational Institute on Aging2025$698,870December 15, 2024November 30, 2029ZELMANN, RINAreporter.nih.gov
Infantile Spasms: Molecular Underpinnings of a Novel Combination TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$693,438March 15, 2018February 28, 2023SWANN, JOHN WILLIAMreporter.nih.gov
A Mobile Health Application to Detect Absence Seizures using Hyperventilation and Eye-Movement RecordingsNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$692,128March 15, 2024August 31, 2024KUPERMAN, RACHELreporter.nih.gov
Subcortical nodes within epileptic network control the cortical disfacilitation to prompt seizure onset in IGE mouse modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$691,250August 15, 2018July 31, 2024ZHOU, CHENGWENreporter.nih.gov
Optimizing Neuromodulation Therapies for Epilepsy: Identifying the Right Patient, Right Place, and Right Time for StimulationNIHNational Institute of Neurological Disorders and Stroke2025$690,763December 1, 2024November 30, 2029ROLSTON, JOHN Dreporter.nih.gov
Adenosine receptor mediated therapies for SUDEPNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$686,876September 15, 2018June 30, 2024BOISON, DETLEVreporter.nih.gov
Alternative Splicing Modulates the Activity of CaV3.1, an Ion Channel Gene Involved in Spinocerebellar Ataxia, Epilepsy, and Autism Spectrum Disorders.NIHNational Institute of General Medical Sciences2022 to 2024$680,482April 1, 2024March 31, 2025RUGGIU, MATTEOreporter.nih.gov
Leveraging genetically-encoded heterogeneity to understand TANDs and seizures in novel models of TSCNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$679,503February 16, 2024November 30, 2028HERNAN, AMANDAreporter.nih.gov
National study of antiepileptic use among patients with dementia in long-term careNIHNational Institute on Aging2025$679,475February 1, 2025November 30, 2029GERLACH, LAUREN BETHreporter.nih.gov
Synaptic changes and hypersynchronous network activity in mTORopathiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$679,278February 1, 2019August 15, 2022WESTON, MATTHEW Creporter.nih.gov
Optimization of EP2 Antagonists for Post-Seizure Cognitive DeficitsNIHNational Institute of Neurological Disorders and Stroke2022$677,532May 1, 2022April 30, 2023GANESH, THOTAreporter.nih.gov
An Interneuron-based Cell Therapy for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021$676,609September 1, 2010May 31, 2022BARABAN, SCOTT Creporter.nih.gov
Inhibitory Network Plasticity in Neurological DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$674,762September 30, 2011May 31, 2024SANTHAKUMAR, VIJAYALAKSHMIreporter.nih.gov
Structural Studies and Drug Discovery to Interrogate the Function of Neuronal SLC4 TransportersNIHNational Institute of Neurological Disorders and Stroke2025$671,775July 1, 2025June 30, 2030WACKER, DANIELreporter.nih.gov
Evaluating the Role of Inflammation in Neonatal EpileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$662,202December 15, 2018November 30, 2024NUMIS, ADAM LAWRENCEreporter.nih.gov
Regulation of Neural Migration During Brain DevelopmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$661,367June 15, 2018February 28, 2023RICCOMAGNO, MARTIN MIGUELreporter.nih.gov
Optimizing Care for Patients with Drug-Resistant EpilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$660,813December 15, 2022November 30, 2027HILL, CHLOE Ereporter.nih.gov
Investigations of Spatial Recognition Memory to Improve Cognitive Outcomes in Epilepsy SurgeryNIHNational Institute of Neurological Disorders and Stroke2025$660,313July 15, 2025June 30, 2030PEDERSEN, NIGEL PAULreporter.nih.gov
Sub-millimeter precision wireless neuromodulation using a microwave split ring resonatorNIHNational Eye Institute2022 to 2024$660,000August 1, 2022July 31, 2025CHENG, JI-XINreporter.nih.gov
Development of IM Formulation of (2S,3S)-SPD for Nerve Agent SeizuresNIHNational Institute of Neurological Disorders and Stroke2021$659,799August 15, 2019May 31, 2023ROGAWSKI, MICHAEL A.reporter.nih.gov
A novel inhibitory target for temporal lobe epilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$659,790December 1, 2017November 30, 2023KROOK-MAGNUSON, ESTHERreporter.nih.gov
Cortical Interneuron Transplantation to Treat Intractable EpilepsyNIHNational Institute of Neurological Disorders and Stroke2025$658,091September 7, 2024August 31, 2029CHUNG, SANGMIreporter.nih.gov
Cellular and network mechanisms of epilepsy and neuromodulationNIHNational Institute of Neurological Disorders and Stroke2025$657,958June 1, 2025May 31, 2030HAN, XUEreporter.nih.gov
Pharmacological and Chemical Approaches to Repurpose an Antiepileptic for Glioblastoma TreatmentNIHNational Institute of General Medical Sciences2022 to 2025$656,000May 11, 2022April 30, 2027DUKHANDE, VIKAS VASUDEOreporter.nih.gov
In utero treatment of Dup15q syndrome via lipid nanoparticle based gene editingNIHNational Institute of Neurological Disorders and Stroke2025$654,339September 1, 2025August 31, 2030WANG, AIJUNreporter.nih.gov
Identification and optimization of verapamil as a novel neuroprotective and anti-inflammatory agent for reducing long-term neurological morbidities following organophosphate-induced status epilepticusNIHNational Institute of Neurological Disorders and Stroke2025$653,216September 1, 2023August 31, 2028DESHPANDE, LAXMIKANT Sreporter.nih.gov
Network dynamics of sleep-wake states in epilepsyNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$650,916January 15, 2023December 31, 2027FAN, JOLINEreporter.nih.gov
Interrogation of Neurological Pathologies Associated with Mutations in Kif1aNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$647,005September 1, 2023August 31, 2025LUTZ, CATHLEEN Mreporter.nih.gov
Role of Neuronal Loss in EpileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$643,504June 1, 2018March 31, 2024HOUSER, CAROLYN Rreporter.nih.gov
MR Fingerprinting for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2025$639,800January 15, 2019March 31, 2030WANG, ZHONG IRENEreporter.nih.gov
Predicting Epilepsy Surgery Outcomes Using Neural Network ArchitectureNIHNational Institute of Neurological Disorders and Stroke2021$638,854August 15, 2019December 31, 2021BONILHA, LEONARDO Freporter.nih.gov
Hippocampal-cortical networks underlying memory retrieval of linguistic knowledgeNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$631,559July 1, 2019June 30, 2025KLEEN, JONATHANreporter.nih.gov
Sodium Channel Dysfunction in Altered Brain DevelopmentNIHNational Institute of Neurological Disorders and Stroke2025$630,414August 1, 2025July 31, 2030SMITH, RICHARD Sreporter.nih.gov
Diagnosis and Genotype-Phenotype Correlations in Early Life Epilepsy and CDKL5 DisorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$627,745January 1, 2023March 31, 2024OLSON, HEATHER ELISAreporter.nih.gov
Novel Counteract Agents To Reduce Mortality And Morbidity Following Organophosphate Status EpilepticusNIHNational Institute of Neurological Disorders and Stroke2021$619,905July 1, 2017March 31, 2024DESHPANDE, LAXMIKANT Sreporter.nih.gov
Acute Modulation of Stereotyped High Frequency Oscillations with a Closed-Loop Brain Interchange System in Drug Resistant EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024$619,657September 1, 2021February 28, 2027INCE, NURI FIRATreporter.nih.gov
Neurophysiology of Human Cortical EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021$613,503April 1, 2010May 31, 2023CASH, SYDNEY Sreporter.nih.gov
The Impact of Local and Reversible Change to GABAergic Inhibitory Signaling on Tumor-Induced Cortical Dysfunction in GliomaNIHNational Institute of Neurological Disorders and Stroke2025$610,554August 1, 2025July 31, 2030GILL, BRIAN JOHN ANDREWreporter.nih.gov
Mechanisms of astrocyte volume regulation and control of neural excitabilityNIHNational Institute of Neurological Disorders and Stroke2025$608,899December 1, 2024November 30, 2029FIACCO, TODD Areporter.nih.gov
The Hippocampus and Brainstem in the Sudden Infant Death SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$607,792September 8, 2017November 30, 2023HAYNES, ROBIN LYNNreporter.nih.gov
Mouse models of Pik3ca brain overgrowth disordersNIHNational Institute of Neurological Disorders and Stroke2021$604,957April 1, 2017March 31, 2022MILLEN, KATHLEEN JOYCEreporter.nih.gov
Optimizing anti-epileptic drug treatment in acute brain injuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$602,640September 30, 2019August 31, 2024ZAFAR, SAHAR Freporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Massachusetts General HospitalBoston, MA26$44.2 million0$0
Stanford UniversityStanford, CA27$34.4 million0$0
University of VirginiaCharlottesville, VA24$32.2 million0$0
Northwestern University at ChicagoChicago, IL25$30.5 million0$0
University of California, San FranciscoSan Francisco, CA25$30.2 million0$0
Columbia University Health SciencesNew York, NY27$29.9 million0$0
University of UtahSalt Lake City, UT10$27.5 million0$0
Baylor College of MedicineHouston, TX29$26.9 million0$0
University of Michigan at Ann ArborAnn Arbor, MI27$24.4 million0$0
University of PennsylvaniaPhiladelphia, PA24$24.1 million0$0
University of California, San DiegoLa Jolla, CA13$23.9 million0$0
Emory UniversityAtlanta, GA22$22.6 million0$0
Yale UniversityNew Haven, CT15$22.2 million0$0
Vanderbilt University Medical CenterNashville, TN12$18.8 million0$0
Boston Children's HospitalBoston, MA24$18.1 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA14$17.4 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX12$17.3 million0$0
University of California Los AngelesLos Angeles, CA14$16.9 million0$0
University of MinnesotaMinneapolis, MN10$16.5 million0$0
University of California at DavisDavis, CA8$16.4 million0$0
University of IowaIowa City, IA13$13.6 million0$0
University of Alabama at BirminghamBirmingham, AL15$13.5 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH15$12.5 million0$0
University of Colorado DenverAurora, CO8$11.8 million0$0
Johns Hopkins UniversityBaltimore, MD10$11.3 million0$0
Mayo Clinic RochesterRochester, MN14$11.2 million0$0
New York University School of MedicineNew York, NY6$10.9 million0$0
University of California-IrvineIrvine, CA9$10.5 million0$0
University of Wisconsin-MadisonMadison, WI7$10.3 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH10$9.8 million0$0
Neuropace, Inc.Mountain View, CA1$9.7 million0$0
University of California-RiversideRiverside, CA10$9.6 million0$0
Albert Einstein College of MedicineBronx, NY2$8.8 million0$0
University of KentuckyLexington, KY7$8.7 million0$0
University of WashingtonSeattle, WA8$8.1 million0$0
Tufts University BostonBoston, MA8$8.1 million0$0
Duke UniversityDurham, NC10$7.7 million0$0
J. David Gladstone InstitutesSan Francisco, CA8$7.5 million0$0
Wayne State UniversityDetroit, MI6$7.1 million0$0
University of Southern CaliforniaLos Angeles, CA4$7.1 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC7$7 million0$0
Broad Institute, Inc.Cambridge, MA2$6.9 million0$0
Case Western Reserve UniversityCleveland, OH5$6.9 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA8$6.6 million0$0
Epitel, Inc.Salt Lake City, UT1$6.3 million0$0
University of Maryland BaltimoreBaltimore, MD7$6.2 million0$0
University of FloridaGainesville, FL4$5.9 million0$0
Brigham and Women's HospitalBoston, MA5$5.8 million0$0
Ohio State UniversityColumbus, OH5$5.8 million0$0
Beth Israel Deaconess Medical CenterBoston, MA4$5.7 million0$0
Harvard Medical SchoolBoston, MA5$5.6 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY10$5.6 million0$0
Nathan S. Kline Institute for Psych ResOrangeburg, NY4$5.5 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL10$5.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY6$5.3 million0$0
Vanderbilt UniversityNashville, TN11$5.3 million0$0
Iowa State UniversityAmes, IA3$5.2 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA8$5.2 million0$0
University of Tennessee Health Sci CTRMemphis, TN6$5.1 million0$0
Boston University Medical CampusBoston, MA3$4.9 million0$0
Research Inst Nationwide Children's HospColumbus, OH4$4.9 million0$0
Oregon Health & Science UniversityPortland, OR5$4.8 million0$0
Allen InstituteSeattle, WA3$4.7 million0$0
University of Illinois at ChicagoChicago, IL2$4.5 million0$0
Agenebio, Inc.Baltimore, MD1$4.4 million0$0
Texas A&m University Health Science CTRCollege Station, TX3$4.4 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ7$4.3 million0$0
Brown UniversityProvidence, RI6$4.2 million0$0
University of Texas at San AntonioSan Antonio, TX5$4.1 million0$0
Carnegie Mellon UniversityPittsburgh, PA4$4.1 million0$0
Makerere University College of Health SciencesKampala3$3.9 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA3$3.8 million0$0
Georgetown UniversityWashington, DC8$3.7 million0$0
Turing Medical Technologies INCSaint Louis, MO1$3.7 million0$0
Henry M. Jackson FDN for the Adv Mil/medBethesda, MD2$3.4 million0$0
University of Vermont & ST Agric CollegeBurlington, VT6$3.4 million0$0
Brandeis UniversityWaltham, MA2$3.4 million0$0
University of ChicagoChicago, IL5$3.3 million0$0
Kephera Diagnostics, LLCFramingham, MA2$3.3 million0$0
Soterya, Inc.Cambridge, MA2$3.1 million0$0
Immunochem Therapeutics, LLCNewton, MA1$3 million0$0
Wake Forest University Health SciencesWinston-Salem, NC5$3 million0$0
University of Miami School of MedicineCoral Gables, FL2$2.9 million0$0
Quasar, Inc.San Diego, CA1$2.9 million0$0
Quiver Bioscience Inc.Cambridge, MA2$2.8 million0$0
ST. Jude Children's Research HospitalMemphis, TN4$2.8 million0$0
Trustees of Boston UniversityBoston, MA3$2.7 million0$0
University of ArizonaTucson, AZ1$2.7 million0$0
Cook Children's Medical CenterFort Worth, TX2$2.6 million0$0
University of HoustonHouston, TX2$2.6 million0$0
Medical College of WisconsinMilwaukee, WI2$2.6 million0$0
Northwestern UniversityChicago, IL1$2.5 million0$0
Cremedical CorporationEast Greenwich, RI1$2.5 million0$0
Southern Methodist UniversityDallas, TX3$2.5 million0$0
Neurologic Solutions, Inc.Mclean, VA1$2.4 million0$0
Universidad Peruana Cayetano HerediaLima1$2.4 million0$0
Univ of Sciences, Tech & Tech of BamakoBamako1$2.4 million0$0
Virginia Commonwealth UniversityRichmond, VA3$2.3 million0$0
Hugo W. Moser Res Inst Kennedy KriegerBaltimore, MD3$2.3 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY1$2.3 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025412$205,225,6080$0
2024424$205,709,0180$0
2023436$213,210,5790$0
2022431$196,864,9410$0
2021413$190,856,3370$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 6 awards here
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 3 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIHJanuary 28, 2027$750,000Notice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 758 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 758 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 758 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 758 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 758 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 758 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 758 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 758 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 758 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 758 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 758 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 758 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 758 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.