Data / Research funding / Crohn's Disease
Crohn's Disease: 279 NIH awards ($270.9M) to 107 organizations
279 NIH awards ($270.9M) in the NIH spending category Crohn's Disease, to 107 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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279 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed with Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $8,401,766 | April 1, 2023 | March 31, 2028 | HYAMS, JEFFREY SAMUEL | reporter.nih.gov |
| Precision IBD via genetics and genomics: integrating International and multi-omic datasets, expanding studies in diverse populations, and defining mechanisms of unmet clinical needs in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $7,890,535 | September 30, 2002 | June 30, 2027 | CHO, JUDY H. | reporter.nih.gov |
| Spatial and temporal resolution to dissect cellular circuits controlling intestinal physiology, immunity, and inflammatory pathologies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $5,934,972 | August 1, 2023 | May 31, 2028 | XAVIER, RAMNIK J | reporter.nih.gov |
| Identifying Microbial, Epithelial and Immune Cell Interactions that Mediate Mucosal Homeostasis and Determine IBD Phenotypes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $5,810,225 | September 19, 2013 | June 30, 2025 | SARTOR, RYAN B | reporter.nih.gov |
| Determinants of inception of inflammation in inflammatory bowel diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $5,397,834 | August 24, 2021 | May 31, 2027 | ANANTHAKRISHNAN, ASHWIN N | reporter.nih.gov |
| Cytokine regulation of mucosal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $4,234,402 | June 6, 2019 | June 30, 2029 | SONNENBERG, GREGORY F | reporter.nih.gov |
| Is Obesity an Infectious Disease?: Gut bacterial and fungal translocation as an underappreciated driver of visceral adipose expansion. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $3,971,090 | September 30, 2021 | June 30, 2026 | DEVKOTA, SUZANNE | reporter.nih.gov |
| Neuregulin-4: A Novel Therapy for Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $2,942,139 | September 20, 2016 | June 30, 2024 | GHOSH, SOUMITRA | reporter.nih.gov |
| Dietary fat-activated colonocyte-macrophage ketone shuttle drives intestinal inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $2,893,480 | July 18, 2025 | June 30, 2029 | RUAN, HAI-BIN | reporter.nih.gov |
| Precise Infliximab Exposure and Pharmacodynamic Control to Achieve Deep Remission in Pediatric Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,803,917 | June 1, 2022 | March 31, 2027 | MINAR, PHILLIP P | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,751,010 | September 23, 2021 | August 31, 2026 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Dietary Regulation of Intestinal Inflammation and Repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $2,700,479 | March 15, 2022 | January 31, 2027 | ARTIS, DAVID | reporter.nih.gov |
| The Role of Crypt Fissioning in IBD Ulcer Healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,649,727 | February 24, 2021 | January 31, 2026 | BARRETT, TERRENCE A. | reporter.nih.gov |
| Role of the environmental sensor, AhR on colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,615,887 | September 27, 2021 | August 31, 2027 | NAGARKATTI, PRAKASH S | reporter.nih.gov |
| Targeting the Mycobiome in Genetically Defined Patients with Crohns Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,513,409 | May 1, 2021 | February 28, 2026 | UNDERHILL, DAVID M. | reporter.nih.gov |
| Dosing and Pilot Efficacy of 2'-Fucosyllactose in Inflammatory Bowel Disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $2,512,710 | July 12, 2018 | June 30, 2027 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Continuation Application for the development of Integrated continuous and single-use (ICS) bioproduction platform (Phase IIB) | NIH | National Institute of General Medical Sciences | 2022 to 2023 | $2,495,306 | January 1, 2016 | March 31, 2024 | SHINKAZH, OLEG | reporter.nih.gov |
| Role of dietary fiber-microbiota Interactions in the development and function of small intestinal T cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,421,990 | September 1, 2021 | July 31, 2026 | CERVANTES BARRAGAN, LUISA | reporter.nih.gov |
| Tuft cell heterogeneity in function, lineage, and structure in ileal inflammatory disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,405,842 | February 15, 2016 | January 31, 2026 | LAU, KEN S | reporter.nih.gov |
| Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,355,463 | September 30, 2002 | June 30, 2027 | CHO, JUDY H. | reporter.nih.gov |
| Impact of symbiotic protists on intestinal T cell homeostasis and inflammation. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,328,152 | March 1, 2021 | February 28, 2026 | HOWITT, MICHAEL R | reporter.nih.gov |
| Gene discoveries in subjects with Crohn's disease of African descent | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,305,204 | March 1, 2011 | June 30, 2025 | KUGATHASAN, SUBRA | reporter.nih.gov |
| Development of a high-throughput epigenomic mapping platform to molecularly phenotype Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,282,116 | September 1, 2022 | August 31, 2025 | JOHNSTONE, ANDREA LYNN | reporter.nih.gov |
| Estrogen-mediated immune regulation in human and experimental inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,237,890 | March 1, 2021 | February 28, 2026 | GOODMAN, WENDY ANN | reporter.nih.gov |
| Mechanisms that alter lymphatic transport in inflammatory bowel disease | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,237,567 | February 7, 2022 | January 31, 2027 | RANDOLPH, GWENDALYN J | reporter.nih.gov |
| Low Dose Interleukin-2 for Regulatory T cell Modulation and the Treatment of Crohnâs Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,232,504 | September 1, 2020 | June 30, 2026 | SNAPPER, SCOTT B | reporter.nih.gov |
| Intestinal single cell analyses and population differences in innate immunity in Crohn's disease drive treatment response and clinical heterogeneity: towards Precision IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,208,042 | February 5, 2020 | January 31, 2025 | CHO, JUDY H. | reporter.nih.gov |
| Montreal-Boston Collaborative GRC | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $2,199,265 | September 30, 2002 | June 30, 2027 | RIOUX, JOHN D. | reporter.nih.gov |
| Population-Based Characterization of Metabolic Pathways to Predict Pediatric Crohn's Disease Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,117,645 | July 15, 2022 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Paneth cell mitochondria and intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $2,076,999 | September 15, 2025 | September 14, 2029 | THEISS, ARIANNE L | reporter.nih.gov |
| Sex Differences in Statural Growth Impairment in Pediatric Crohn's Disease: Part 2 | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 to 2025 | $2,074,213 | September 11, 2023 | May 31, 2028 | GUPTA, NEERA | reporter.nih.gov |
| Novel Oral Yeast Immunotherapies for Ulcerative Colitis (Fast-track) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $2,057,937 | May 1, 2022 | April 30, 2025 | YANG, ZHIYONG | reporter.nih.gov |
| Assessing biomarkers of intestinal fibrosis and inflammation in Crohn's Disease via an endoscopic imaging catheter | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $2,046,791 | September 1, 2020 | August 31, 2025 | HIGGINS, PETER D.R. | reporter.nih.gov |
| Selective targeting of high affinity alpha4 integrins as a safe treatment strategy for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $1,996,323 | September 16, 2020 | June 30, 2026 | WOODSIDE, DARREN G | reporter.nih.gov |
| InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammation | NIH | National Center for Advancing Translational Sciences | 2022 to 2023 | $1,980,716 | May 1, 2022 | January 31, 2025 | THELIN, BILL | reporter.nih.gov |
| Robust quantitative MR imaging markers of response to therapy in Crohn’s Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,968,390 | April 1, 2021 | December 31, 2026 | KURUGOL, SILA | reporter.nih.gov |
| PARP1 and PARylation as novel effectors of gut inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,948,301 | June 1, 2023 | March 31, 2027 | KIELA, PAWEL R | reporter.nih.gov |
| Inflammatory cascades disrupt Treg function through epigenetic mechanisms | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $1,945,746 | February 10, 2021 | January 31, 2026 | FAUBION, WILLIAM A | reporter.nih.gov |
| Indole dysbiosis and mucosal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,930,131 | June 1, 2012 | December 31, 2028 | COLGAN, SEAN P | reporter.nih.gov |
| Gut Dysbiosis and Cardiac Remodeling in IBD | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,928,316 | September 1, 2020 | August 31, 2025 | LI, QINGJIE | reporter.nih.gov |
| Novel biomaterials for IBD treatment | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,903,299 | May 1, 2020 | April 30, 2024 | MOON, JAMES J. | reporter.nih.gov |
| A nanofiber-hydrogel composite plug for perianal fistula repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,883,553 | March 1, 2023 | February 28, 2027 | MAO, HAI-QUAN | reporter.nih.gov |
| Bacteriophage pathobiology of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,875,144 | May 6, 2020 | February 28, 2025 | ROUND, JUNE LOUISE | reporter.nih.gov |
| Septins in intestinal fibrosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,865,031 | May 1, 2023 | April 30, 2027 | RIEDER, FLORIAN | reporter.nih.gov |
| Clinical Trial of ENhancing Recovery in CHildren Undergoing Surgery - ENRICH-US | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,861,857 | September 9, 2019 | June 30, 2025 | RAVAL, MEHUL V. | reporter.nih.gov |
| Polymicrobial interactions in Crohn's Disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,852,209 | July 8, 2019 | June 30, 2025 | GHANNOUM, MAHMOUD A | reporter.nih.gov |
| Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,850,523 | August 15, 2019 | May 31, 2025 | HUANG, JING | reporter.nih.gov |
| The role of IL-1ß-inducing pathobionts in the pathogenesis of Crohn’s disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,843,192 | August 1, 2017 | March 31, 2027 | KAMADA, NOBUHIKO | reporter.nih.gov |
| Statistical Methods for Microbiome and Metagenomics | NIH | National Institute of General Medical Sciences | 2022 to 2025 | $1,807,642 | September 15, 2017 | August 31, 2026 | LEE, HONGZHE | reporter.nih.gov |
| Vitamin D Receptor Regulation of Microbiota in Intestinal Epithelia | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,798,591 | September 15, 2023 | July 31, 2028 | SUN, JUN | reporter.nih.gov |
| Systematic dissection of gut cellular circuits [at single cell resolution] | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $1,795,970 | August 1, 2017 | May 31, 2023 | XAVIER, RAMNIK J | reporter.nih.gov |
| The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,790,331 | February 1, 2021 | June 4, 2023 | SWANSON, GARTH R | reporter.nih.gov |
| Hypoxia, HIF, and Mucosal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,761,297 | September 25, 1995 | March 31, 2026 | COLGAN, SEAN P | reporter.nih.gov |
| Celiac and inflammatory bowel diseases: functional post-GWAS approach | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,722,912 | August 19, 2024 | July 31, 2029 | TYCKO, BENJAMIN | reporter.nih.gov |
| Granzyme B PET imaging as a marker of inflammatory bowel disease activity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,722,828 | September 4, 2020 | May 31, 2025 | MAHMOOD, UMAR | reporter.nih.gov |
| Innate immune responses to tissue infection by intestinal fungi inhibit wound repair | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,580,412 | November 14, 2023 | October 31, 2028 | STAPPENBECK, THADDEUS S | reporter.nih.gov |
| Automated Measurement of Bowel Damage Using Enterography Imaging to Predict Clinical Outcomes in Crohn’s Disease. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,578,048 | July 1, 2020 | April 30, 2026 | STIDHAM, RYAN WILLIAM | reporter.nih.gov |
| Host-Microbiota-Diet Interactions in Metabolic Syndrome and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,567,538 | April 15, 2010 | December 31, 2024 | GEWIRTZ, ANDREW T | reporter.nih.gov |
| Creeping fat and Crohn's disease associated strictures | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,556,335 | July 15, 2020 | March 31, 2026 | RIEDER, FLORIAN | reporter.nih.gov |
| Chloroquine-based polymer particles as oral non-absorbable treatment of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,552,302 | April 1, 2020 | February 28, 2026 | OUPICKY, DAVID | reporter.nih.gov |
| A role for the stomach in protection from colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,519,827 | May 1, 2020 | January 31, 2025 | BOONE, DAVID L. | reporter.nih.gov |
| Role of microbiota, host genetics and mesenteric adipose in Crohn's disease fibrosis and post-op recurrence. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,514,700 | January 20, 2020 | December 31, 2025 | DEVKOTA, SUZANNE | reporter.nih.gov |
| Microbiota-mediated fibrotic remodeling in the inflamed intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,497,126 | June 1, 2020 | May 31, 2025 | ARTHUR, JANELLE C | reporter.nih.gov |
| Central metabolism of Salmonella in the inflamed gut | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $1,472,554 | May 1, 2015 | July 31, 2030 | WINTER, SEBASTIAN E | reporter.nih.gov |
| Genomic and Immunologic Characterization of Inflammatory Bowel Disease and its Phenotypes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $1,470,541 | September 30, 2002 | June 30, 2027 | SILVERBERG, MARK S. | reporter.nih.gov |
| gd IELs in chronic ileitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,441,543 | July 1, 2023 | April 30, 2027 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| Contributions of the enterocyte brush border to intestinal health and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,425,632 | July 1, 2023 | April 30, 2027 | VANDUSSEN, KELLI LYNN | reporter.nih.gov |
| Cytokines and Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,412,135 | July 3, 1990 | April 30, 2024 | COMINELLI, FABIO | reporter.nih.gov |
| Microbial ecology of the inflamed intestine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $1,411,946 | September 24, 2018 | August 31, 2024 | AHMER, BRIAN M | reporter.nih.gov |
| A Novel Immunological Probiotic for Treating Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,409,741 | July 1, 2018 | September 30, 2023 | FANGER, GARY | reporter.nih.gov |
| Oral elafin formulation for intestinal fibrosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,403,285 | April 1, 2022 | February 28, 2027 | KOON, HON WAI | reporter.nih.gov |
| Gut Microbe-Derived Nitric Oxide As A Signal To Host: Role In Normal Physiology And In Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $1,402,632 | March 1, 2021 | February 28, 2025 | STAMLER, JONATHAN S. | reporter.nih.gov |
| Actions of Resolvins on Intestinal Inflammation and Pain | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,399,647 | April 1, 2020 | March 31, 2025 | WILEY, JOHN W | reporter.nih.gov |
| Predicting Clinical Phenotypes in Crohn's Disease Using Machine Learning and Single-Cell 'omics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $1,381,450 | May 1, 2023 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Mechanisms of fungal involvement during intestinal disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,348,169 | May 8, 2020 | February 28, 2025 | ROUND, JUNE LOUISE | reporter.nih.gov |
| CD39 in gamma delta intraepithelial lymphocyte function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,328,326 | August 1, 2024 | May 31, 2028 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| Genetic and Small Molecule Regulation of Mechanisms of Crohn’s Disease Stricture Formation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,323,025 | May 1, 2024 | April 30, 2028 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Role of Gene-Microbial Interactions in the Development of Crohn's Disease-like Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,270,015 | September 20, 2019 | June 30, 2024 | NUNEZ, GABRIEL | reporter.nih.gov |
| IL-36 cytokines and gut immunity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,255,633 | December 24, 2019 | November 30, 2024 | DENNING, TIMOTHY L | reporter.nih.gov |
| Intestinal IL-17RA signaling and mucosal host defense | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,238,952 | July 1, 2019 | April 30, 2025 | KUMAR, PAWAN | reporter.nih.gov |
| Dysbiosis in Hirschsprung Associated Enterocolitis Pathogenesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,224,406 | April 1, 2020 | January 31, 2024 | GOSAIN, ANKUSH | reporter.nih.gov |
| Characterization of a commensal enteric virus | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $1,195,175 | September 20, 2011 | June 30, 2030 | CADWELL, KEN HASHIGIWA | reporter.nih.gov |
| Mechanisms by which human milk-derived oligosaccharides protect intestinal barrier and attenuate inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $1,190,720 | May 15, 2024 | March 31, 2028 | YAN, FANG | reporter.nih.gov |
| The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,166,868 | April 10, 2020 | January 31, 2025 | COATES, MATTHEW D | reporter.nih.gov |
| CD4 T cell stemness and inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,157,862 | September 1, 2020 | May 31, 2025 | HARRINGTON, LAURIE ELLEN | reporter.nih.gov |
| Mechanisms of TL1A-driven Paneth Cell dysfunction in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,147,500 | January 1, 2020 | December 31, 2024 | TARGAN, STEPHAN R. | reporter.nih.gov |
| Effects of host endocannabinoid signaling on Enterobacteriaceae infection | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,140,243 | June 6, 2024 | April 30, 2029 | ELLERMANN, MELISSA | reporter.nih.gov |
| Intestinal lysozyme controls mucosal immune response to microbiota | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,115,623 | July 1, 2019 | June 30, 2025 | GAO, NAN | reporter.nih.gov |
| Characterization of a commensal enteric virus | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,102,694 | September 20, 2011 | August 31, 2023 | CADWELL, KEN HASHIGIWA | reporter.nih.gov |
| Paneth cell phenotype as a predictive biomarker for ulcerative colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,085,430 | September 24, 2020 | July 31, 2025 | LIU, TA-CHIANG | reporter.nih.gov |
| Pathogenic Role of Mechanical Stress in Fibrosis and Tissue Remodeling in Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,066,500 | April 21, 2020 | January 31, 2026 | SHI, XUAN-ZHENG PETER | reporter.nih.gov |
| Cellular and molecular mechanisms of cigarette smoking-induced Paneth cell abnormality | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $1,063,125 | July 1, 2020 | April 30, 2025 | LIU, TA-CHIANG | reporter.nih.gov |
| The function of lysophosphatidic acid receptor LPA5R in intestinal inflammation and epithelial damage | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,014,004 | September 20, 2018 | May 31, 2024 | YUN, CHANGHYON CHRIS | reporter.nih.gov |
| GPR120 regulation of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $1,001,738 | May 1, 2020 | March 31, 2024 | CONG, YINGZI | reporter.nih.gov |
| Role of IRGM proteins in immunity to enteric bacteria | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $961,519 | August 1, 2019 | July 31, 2025 | TAYLOR, GREGORY A | reporter.nih.gov |
| Early-life Risk Factors for Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $951,196 | August 12, 2021 | July 31, 2026 | AGRAWAL, MANASI | reporter.nih.gov |
| Inhibiting Bcl-2-regulated intestinal fibrosis in models of Crohn’s Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $934,680 | July 1, 2018 | May 31, 2024 | HIGGINS, PETER D.R. | reporter.nih.gov |
| Paneth cell heterogeneity in infection and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $925,915 | March 15, 2022 | January 31, 2024 | GAO, NAN | reporter.nih.gov |
| Changes in actin dynamics regulated by villin and gesolin are determinants of cell fate and may be key to gastrointestinal inflammatory disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $923,894 | September 20, 2018 | August 31, 2024 | KHURANA, SEEMA | reporter.nih.gov |
| Multi-omic characterization of genetic variants in IBD risk loci | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $919,886 | March 1, 2024 | February 29, 2028 | FUREY, TERRENCE S. | reporter.nih.gov |
| Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $905,290 | September 18, 2023 | August 31, 2027 | SCHULTZ, KENNETH | reporter.nih.gov |
| Unconventional myosins and the regulation of gut barrier integrity and restitution during inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $905,274 | September 15, 2020 | July 31, 2024 | IVANOV, ANDREI IVANOVICH | reporter.nih.gov |
| Paneth cell heterogeneity in infection and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $895,175 | March 15, 2022 | January 31, 2026 | GAO, NAN | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $885,846 | September 23, 2021 | September 2, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Macrophage LRRK2 activity regulates gut epithelial homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $882,538 | September 1, 2024 | June 30, 2027 | LIU, TA-CHIANG | reporter.nih.gov |
| Nuclear Receptor Control of T Cell Function in Discrete Intestinal Microenvironments | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $874,967 | September 23, 2021 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| REGULATION OF NICHE CELL DIFFERENTIATION TO SUSTAIN INTESTINAL STEM CELL REGENERATION AGAINST GUT INFLAMMATION | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $870,194 | January 1, 2020 | December 31, 2024 | HAN, XIAONAN | reporter.nih.gov |
| Quantitative Ultrasound Imaging Biomarkers of Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $867,754 | March 11, 2019 | December 31, 2024 | CHEN, SHIGAO | reporter.nih.gov |
| Agr2 regulates host-microbe responses in Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $859,704 | July 2, 2025 | April 30, 2029 | LONGMAN, RANDY S | reporter.nih.gov |
| Mitochondrial Dysfunction and Mitophagy in Ileitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $833,371 | August 15, 2019 | July 31, 2024 | THEISS, ARIANNE L | reporter.nih.gov |
| A Novel Approach to Restore Epithelial Barrier Homeostasis to Treat Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $795,004 | September 15, 2019 | November 15, 2022 | GRAHAM, W VALLEN | reporter.nih.gov |
| The link between oral bacteria and gut disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $782,216 | January 8, 2019 | December 31, 2024 | KAMADA, NOBUHIKO | reporter.nih.gov |
| Genomic Analysis of Perianal Fistulizing Crohn's Disease across Ancestries | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $771,196 | September 16, 2020 | August 31, 2024 | KUGATHASAN, SUBRA | reporter.nih.gov |
| Characterizing the Biologic Evolution of Crohn's Disease Like Pouch Inflammation in Ulcerative Colitis Patients After Restorative Proctocolectomy with Ileal Pouch Anal Anastomosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $763,616 | February 1, 2022 | January 31, 2027 | KAYAL, MAIA | reporter.nih.gov |
| POP3 regulates type I interferon and ameliorates intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $758,542 | July 3, 2025 | April 30, 2030 | STEHLIK, CHRISTIAN | reporter.nih.gov |
| Host-Microbiota Interactions in Crohn's Disease-associated Spondyloarthritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $751,598 | April 2, 2018 | January 31, 2023 | LONGMAN, RANDY S | reporter.nih.gov |
| IL1 as a Driver of Mucosal Immune Dysregulation in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $750,700 | January 10, 2022 | February 4, 2027 | MITSIALIS, VANESSA | reporter.nih.gov |
| Aberrant N-glycosylation in Crohn's disease: Opportunity for precision medicine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $725,520 | September 15, 2025 | June 30, 2030 | MELIA, JOANNA MILLER PELOQUIN | reporter.nih.gov |
| The role of local iron homeostasis in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $705,236 | August 6, 2021 | July 31, 2026 | BESSMAN, NICHOLAS J. | reporter.nih.gov |
| microRNA-dependent regulation of intestinal T-cells² | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $699,750 | January 13, 2018 | December 31, 2023 | DE ZOETEN, EDWIN FULCO | reporter.nih.gov |
| Predicting Clinical Phenotypes in Crohn's Disease Using Machine Learning and Single-Cell 'omics | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $696,092 | March 25, 2025 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Population-Based Characterization of Metabolic Pathways to Predict Pediatric Crohn's Disease Outcomes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $688,350 | April 25, 2025 | April 30, 2027 | SYED, SANA | reporter.nih.gov |
| Malassezia Immune Responses as Biomarkers of IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $680,687 | August 15, 2025 | May 31, 2030 | UNDERHILL, DAVID M. | reporter.nih.gov |
| CD4+ Tissue resident memory T-cells in Crohnâs Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $677,055 | September 30, 2020 | July 31, 2025 | BISHU, SHRINIVAS | reporter.nih.gov |
| Understanding the Interaction between Host Genetics, Immune response, and Gut Microbes in Post-operative Recurrence of Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $648,000 | March 1, 2024 | February 29, 2028 | LEE, SUN-HO | reporter.nih.gov |
| Understanding hematopoietic stem cell dysfunction in refractory Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $645,617 | July 1, 2025 | April 30, 2030 | COHEN, LOUIS JARED | reporter.nih.gov |
| Validation of Immunometabolic NLRX1 Therapeutics for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $643,417 | April 1, 2019 | April 30, 2023 | LEBER, ANDREW | reporter.nih.gov |
| Pathogenic Heterogeneity in Mucosal Stem Cells in Pediatric Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $640,193 | August 10, 2018 | June 30, 2024 | XIAN, WA | reporter.nih.gov |
| Genetic variation in the metal transporter ZIP8 and impact on the innate immune response in the gut | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $625,763 | July 1, 2019 | August 31, 2024 | MELIA, JOANNA MILLER PELOQUIN | reporter.nih.gov |
| Precision therapeutics of inflammatory bowel disease guided by Boolean logic | NIH | National Center for Advancing Translational Sciences | 2021 to 2022 | $621,778 | August 28, 2020 | July 31, 2023 | SAHOO, DEBASHIS | reporter.nih.gov |
| Phase 2 Proof-of-Concept Efficacy of BT-11 in Crohn's Disease Patients | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $613,188 | September 14, 2020 | December 15, 2023 | LICHTIGER, SIMON | reporter.nih.gov |
| The Role of Macrophages in Immune Responses to Giardia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $612,377 | July 1, 2014 | July 31, 2025 | SINGER, STEVEN M | reporter.nih.gov |
| Effect of an Anti-Inflammatory Diet on Gut Homeostasis in Active and Experimental Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $610,350 | March 1, 2021 | December 31, 2025 | RAFFNER, ABIGAIL | reporter.nih.gov |
| The Intestinal Mycobiome and IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2025 | $610,350 | March 1, 2021 | February 28, 2026 | DI MARTINO, LUCA | reporter.nih.gov |
| Bile acid-dependent T cell regulation in the intestine | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $601,831 | February 6, 2019 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Assessing Predictors of Response to Anti-Tumor Necrosis Alpha Therapy in Early Crohns Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $568,026 | April 1, 2019 | June 30, 2024 | UNGARO, RYAN | reporter.nih.gov |
| Impact of AIM2 on Intestinal Stem Cell Differentiation During Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $567,205 | January 1, 2025 | November 30, 2028 | WILSON, JUSTIN ETHAN | reporter.nih.gov |
| A Fully Remote Pilot Randomized Controlled Trial to Investigate the Impact of Insomnia Treatment on Crohn’s disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $566,855 | February 15, 2023 | November 30, 2027 | SALWEN-DEREMER, JESSICA K | reporter.nih.gov |
| Gut microbiota metabolite sensing licenses IEC to cross talk with T cells to inhibit intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $556,826 | February 15, 2023 | October 1, 2023 | CONG, YINGZI | reporter.nih.gov |
| Analysis of autophagy risk genes in inflammation and tissue homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $538,256 | January 1, 2013 | October 31, 2022 | XAVIER, RAMNIK J | reporter.nih.gov |
| USING SINGLE-CELL RNA AND PROTEIN APPROACHES TO ELUCIDATE MOLECULAR DETERMINANTSAND PREDICTORS OF INFLAMMATORY BOWEL DISEASES | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $525,896 | April 1, 2020 | December 31, 2023 | BOLAND, BRIGID S | reporter.nih.gov |
| Exploring Glutamate Carboxypeptidase II (GCPII) Dysregulation in Human and Experimental IBD | NIH | Office of the Director, National Institutes of Health | 2022 to 2025 | $520,560 | January 1, 2022 | December 31, 2026 | PETERS, DIANE E. | reporter.nih.gov |
| Discovery and Biological Signatures of Microbiome-Derived Xanthohumol Metabolites and their Role in Ameliorating Inflammatory Bowel Disease | NIH | National Center for Complementary & Integrative Health | 2021 | $516,964 | September 21, 2018 | August 31, 2025 | STEVENS, JAN FREDERIK | reporter.nih.gov |
| Nuclear Receptor Networks in Mucosal Immune Regulation | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $511,879 | July 30, 2021 | September 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Nuclear Receptor Networks in Mucosal Immune Regulation | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $511,877 | July 30, 2021 | April 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Inflammatory cascades disrupt Treg function through epigenetic mechanisms | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $505,712 | February 10, 2021 | January 31, 2027 | FAUBION, WILLIAM A | reporter.nih.gov |
| Precision Medicine in Inflammatory Bowel Disease: Refining the Clinical and Genomic Predictors of Response to Anti-IL-12/23 Therapy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $501,936 | April 17, 2023 | February 29, 2028 | CUSHING-DAMM, KELLY COLLEEN | reporter.nih.gov |
| Mechanisms of gut epithelial DUOX-mediated intestinal homeostasis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $497,721 | April 1, 2018 | January 31, 2023 | KAO, JOHN Y | reporter.nih.gov |
| Structure function studies in intestinal epithelial JAM | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $486,750 | May 1, 2002 | April 30, 2024 | PARKOS, CHARLES A | reporter.nih.gov |
| Dysregulation of inflammation resolution as therapeutic target for IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $486,254 | July 1, 2023 | March 31, 2028 | MERIWETHER, DAVID | reporter.nih.gov |
| Intestinal O-GlcNAc signaling and mucosal host defense | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $483,958 | September 20, 2021 | February 22, 2022 | RUAN, HAI-BIN | reporter.nih.gov |
| Characterization of E. coli-specific T cells in Crohn's disease | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $476,075 | February 1, 2022 | January 31, 2024 | LORD, JAMES DANIEL | reporter.nih.gov |
| Signaling through intestinal MUC receptors by bacterial Serine Proteases of Enterobacteriaceae | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $474,419 | May 23, 2022 | April 30, 2025 | RUIZ, FERNANDO | reporter.nih.gov |
| Prevention of Crohns Disease in High-Risk Individuals | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $470,417 | May 1, 2024 | February 28, 2029 | LOPES, EMILY WALSH | reporter.nih.gov |
| Bacterial translocation to mesenteric adipose tissue drives pathogenic stromal-B cell interactions leading to inflammatory IgG | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $466,125 | February 3, 2023 | January 31, 2025 | GRASSET, EMILIE K | reporter.nih.gov |
| Effect of Maternal IBD, Microbiome and Early Life Events on the Bacterial Colonization and Mucosal Immunity in the Offspring | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $465,125 | August 13, 2021 | July 31, 2024 | PETER, INGA | reporter.nih.gov |
| Role of Rip2 in the Generation of Pathogenic Th17/Th1 T-cells and Ileitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $459,250 | December 7, 2020 | November 30, 2023 | CROTHER, TIMOTHY ROBERT | reporter.nih.gov |
| Aim protein-based anti-inflammatory therapeutic for the treatment of IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $456,817 | September 19, 2023 | August 31, 2025 | POHL ROBINSON, CATHERINE | reporter.nih.gov |
| Advanced sequencing as a novel diagnostic tool to discover strain-level variation and function of mucosal-adherent bacteria contributing to IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $451,773 | September 1, 2019 | August 31, 2024 | WANG, JEREMY R | reporter.nih.gov |
| IBD Gene Mapping by Clinical and Population Subset | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $451,377 | September 30, 2002 | July 31, 2022 | BRANT, STEVEN R | reporter.nih.gov |
| Microbiota, Tertiary Lymphoid Structures and Chronic Inflammation in the Human Gut | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $451,376 | April 6, 2021 | March 31, 2024 | BOGUNOVIC, MILENA | reporter.nih.gov |
| The Interconnection between Mouth and Gut: Understanding the Microbial and Host Factors Influencing Susceptibility to Periodontitis and Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $450,842 | September 30, 2021 | August 31, 2024 | THUMBIGERE-MATH, VIVEK | reporter.nih.gov |
| Vagal control of tissue SUMOylation as a novel anti-inflammatory target in IBD | NIH | National Center for Complementary & Integrative Health | 2022 to 2023 | $442,750 | July 11, 2022 | June 30, 2025 | YANG, WEI | reporter.nih.gov |
| The Study of Families with Heritable Crohn's Disease to Support Rational Design of Microbiodata-Based Therapies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $438,852 | January 16, 2020 | December 31, 2022 | CHEN, LEA A | reporter.nih.gov |
| Role of TRIF-Dependent TLR Signaling in Intestinal Mucosa | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $437,500 | July 1, 2012 | June 30, 2023 | TARGAN, STEPHAN R. | reporter.nih.gov |
| Genetic Regulation of Tissue Fibrosis in Human Intestinal Organoids | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $437,250 | June 15, 2021 | April 30, 2024 | DENSON, LEE ARMISTEAD | reporter.nih.gov |
| Harnessing gut microbiota to reduce inflammation using broccoli-sprout diets | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $436,046 | September 1, 2022 | August 31, 2025 | PELLEGRINI, SUZANNE ISHAQ | reporter.nih.gov |
| Antioxidant regulation of intestinal homeostasis and disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $435,876 | April 1, 2020 | April 19, 2023 | SHORT, SARAH PALMER | reporter.nih.gov |
| The Study of Families with Heritable Crohn's Disease to Support Rational Design of Microbiodata-Based Therapies | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $435,473 | February 24, 2021 | December 31, 2025 | CHEN, LEA A | reporter.nih.gov |
| Engineered immunotherapies neutralizing interleukin-22 binding protein | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2023 | $434,847 | September 1, 2022 | June 30, 2025 | COLLIER, JOEL H | reporter.nih.gov |
| Discovery of aberrant enhancer activities during gut development that underlie genetic predisposition to pediatric Crohn's disease | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $431,750 | September 24, 2021 | August 31, 2024 | SETHUPATHY, PRAVEEN | reporter.nih.gov |
| NIDDK IBD Genetics Consortium Genetic Research Center | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $429,989 | September 30, 2002 | October 31, 2023 | DUERR, RICHARD H | reporter.nih.gov |
| Investigation of Human Gut-Derived Mesenchymal Stem Cells for Cellular Therapy | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $429,545 | July 17, 2024 | June 30, 2027 | CHINNADURAI, RAGHAVAN | reporter.nih.gov |
| Inflammatory Bowel Disease Susceptibility Gene Regulation of Anemia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $427,625 | March 3, 2021 | February 28, 2023 | MCCOLE, DECLAN | reporter.nih.gov |
| Novel high-throughput in vivo approach to define pathobionts driving colitis | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $427,625 | February 13, 2021 | January 31, 2024 | ARTHUR, JANELLE C | reporter.nih.gov |
| Impact of developmental exposure to PFAS on the microbiota-gut-brain axis | NIH | National Institute of Environmental Health Sciences | 2023 | $423,657 | July 22, 2023 | June 30, 2025 | GAREAU, MELANIE G | reporter.nih.gov |
| The pathogenic roles of GSDMD-dependent gut epithelium extracellular vesicles in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $420,472 | April 8, 2021 | November 30, 2021 | PIZARRO, THERESA TORRES | reporter.nih.gov |
| Genetic and Epigenetic Regulation of Intestinal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $419,922 | April 2, 2018 | May 31, 2022 | BAGNAT, MICHEL | reporter.nih.gov |
| Claudin expression regulates mucus function | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $405,876 | September 26, 2022 | August 31, 2025 | CAPALDO, CHRISTOPHER TODD | reporter.nih.gov |
| Mechanisms of Experimental Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $402,500 | July 1, 1999 | August 31, 2023 | COMINELLI, FABIO | reporter.nih.gov |
| Harnessing iron acquisition to hinder enterobacterial pathogenesis | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $399,521 | June 1, 2015 | March 31, 2023 | RAFFATELLU, MANUELA | reporter.nih.gov |
| Systems biology of microbe-mediated glucosinolate bioconversion in inflammatory bowel disease | NIH | National Center for Complementary & Integrative Health | 2021 | $399,031 | September 20, 2018 | August 31, 2023 | PAPIN, JASON | reporter.nih.gov |
| Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $395,119 | September 18, 2023 | November 30, 2024 | SCHULTZ, KENNETH | reporter.nih.gov |
| Skeletal Health and Bone Marrow Composition in Adolescents with Crohn’s Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $391,380 | August 4, 2023 | May 31, 2027 | GORDON, REBECCA JUDITH | reporter.nih.gov |
| Clinical, imaging, and endoscopic outcomes of children newly diagnosed with Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $391,223 | September 7, 2021 | March 31, 2023 | HYAMS, JEFFREY SAMUEL | reporter.nih.gov |
| Immunomodulatory effects of bilirubin are mediated through aryl hydrocarbon receptor, O2 and purinergic pathways | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $389,671 | February 1, 2017 | January 31, 2023 | LONGHI, MARIA SERENA | reporter.nih.gov |
| Mechanisms of cell death and autophagy in intestinal epithelial cells in inflammation and cancer | NIH | National Cancer Institute | 2021 | $387,731 | March 21, 2017 | February 28, 2022 | MOSCAT, JORGE | reporter.nih.gov |
| Bile acid-dependent T cell regulation in the intestine | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $386,709 | January 24, 2023 | January 31, 2025 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Molecular characterization of the role of RNASET2 in Severe Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $375,750 | September 19, 2019 | July 31, 2022 | TARGAN, STEPHAN R. | reporter.nih.gov |
| Impact of dysbiotic and symbiotic catabolism of luminal amino acids on intestinal epithelial barrier function and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $375,080 | September 20, 2023 | August 31, 2025 | ALAM, M. ASHFAQUL | reporter.nih.gov |
| Utility of Random Biopsies in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $365,625 | September 21, 2022 | August 31, 2024 | LEWIS, JAMES D | reporter.nih.gov |
| Novel Nanoligomer-Based Therapeutics for Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $364,674 | March 6, 2022 | August 31, 2023 | NAGPAL, PRASHANT | reporter.nih.gov |
| A20 Mediated Regulation of Colitis and Spondyloarthritis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $363,375 | April 1, 2012 | February 28, 2022 | MA, AVERIL I | reporter.nih.gov |
| Endogenous and Dietary Sphingolipids as Modulators in Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $363,375 | June 15, 2018 | May 31, 2023 | SABA, JULIE D | reporter.nih.gov |
| Precision therapeutics of inflammatory bowel disease guided by Boolean logic | NIH | National Center for Advancing Translational Sciences | 2023 | $355,500 | August 28, 2020 | July 31, 2024 | SAHOO, DEBASHIS | reporter.nih.gov |
| A Novel Device Alternative to Temporary Diverting Ostomies after Rectal Cancer Surgery | NIH | National Cancer Institute | 2021 to 2022 | $353,509 | June 22, 2022 | January 31, 2023 | FONG, KENTON DODYAN | reporter.nih.gov |
| Identifying population-specific IBD-associated mutations, genes and pathways | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $339,000 | September 20, 2019 | June 30, 2022 | ITAN, YUVAL | reporter.nih.gov |
| Sarcopenia as a Preoperative Risk Stratification Tool Among Older Adults with Inflammatory Bowel Disease | NIH | National Institute on Aging | 2022 to 2023 | $339,000 | September 1, 2022 | May 31, 2024 | FAYE, ADAM SCOTTE | reporter.nih.gov |
| Acinar Biology and Pancreatic Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $338,526 | June 1, 2018 | March 31, 2023 | GROBLEWSKI, GUY E | reporter.nih.gov |
| Regulation of Intestinal Tight Junction Barrier and Inflammation by Autophagy | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $337,007 | July 1, 2018 | June 30, 2023 | NIGHOT, PRASHANT | reporter.nih.gov |
| Frailty in Inflammatory Bowel Diseases | NIH | National Institute on Aging | 2021 to 2022 | $336,000 | August 15, 2021 | October 31, 2023 | KOCHAR, BHARATI | reporter.nih.gov |
| Endoplasmic Reticulum Stress Controls Innate Lymphoid Cells in Intestinal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $334,668 | September 1, 2024 | April 30, 2029 | CAO, SIYAN | reporter.nih.gov |
| A new model of ILC3-independent innate colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $333,103 | August 9, 2019 | May 31, 2023 | BOONE, DAVID L. | reporter.nih.gov |
| Aging lymphocytes: senescence programs in lymphocytes relevant to human inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $327,210 | January 4, 2023 | July 2, 2024 | GONZALEZ SALGADO, MICHELLE M | reporter.nih.gov |
| Novel immunosuppressive mechanism of human bone marrow mesenchymal stem cells in experimental Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $324,379 | April 15, 2017 | December 31, 2023 | DAVE, MANEESH | reporter.nih.gov |
| Integrating metagenomics data into accurate mass stool metabolite identifications | NIH | Office of the Director, National Institutes of Health | 2022 | $319,166 | September 20, 2022 | September 19, 2024 | FIEHN, OLIVER | reporter.nih.gov |
| Bile acid-dependent T cell regulation in the intestine | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $314,388 | February 6, 2019 | September 1, 2022 | SUNDRUD, MARK SCOTT | reporter.nih.gov |
| Investigating the role of natural and engineered curli fibers in mediating interactions with the gut epithelium | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $305,070 | April 1, 2017 | March 31, 2022 | JOSHI, NEEL SATISH | reporter.nih.gov |
| Small molecule drugs targeting gut dysbiosis to manage inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $304,553 | June 10, 2022 | March 10, 2023 | WALLACE, BRET DAVID | reporter.nih.gov |
| Mechanisms of Gastrointestinal COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $304,049 | March 10, 2022 | July 14, 2022 | CIORBA, MATTHEW AARON | reporter.nih.gov |
| A Next-Generation Therapeutic for Treatment of TNFα-mediated Inflammatory Diseases | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $301,488 | September 30, 2022 | August 31, 2024 | WAHL, ALAN F | reporter.nih.gov |
| Therapeutic Antibodies for Treating Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $300,241 | May 1, 2021 | April 30, 2023 | SCHWIMMER, LAUREN JENNIFER | reporter.nih.gov |
| An oral TNFα inhibitor for inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $299,981 | September 23, 2022 | August 31, 2024 | WAHL, ALAN F | reporter.nih.gov |
| Understanding the role of Epigenetic Reader SP140 in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $291,193 | September 20, 2018 | August 31, 2022 | ANTHONY, ROBERT MCCULLOUGH | reporter.nih.gov |
| Rapid and Quantitative Point Of Care Stool Assays For The Diagnosis And Monitoring Of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $280,160 | April 1, 2022 | September 30, 2023 | ALPADI, KANNAN | reporter.nih.gov |
| Preclinical validation of small molecule immunomodulators for the treatment of Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $271,865 | September 1, 2023 | March 31, 2024 | NEGGERS, JASPER E | reporter.nih.gov |
| Interaction of Mesenteric Adipose Tissue Physiology, Expansion, and Inflammation with Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $271,050 | June 1, 2023 | December 31, 2024 | GLINIAK, CHRISTY M | reporter.nih.gov |
| Functional outcomes of N6-methyladenosine (m6A) recognition by IMP1 during environment induced intestinal stress | NIH | National Institute of Environmental Health Sciences | 2021 | $264,000 | June 16, 2020 | May 31, 2023 | HAMILTON, KATHRYN ELIZABETH | reporter.nih.gov |
| Enabling IL-2 as an Anti-inflammatory Agent through Local Dose-controlled Endoscopic Delivery | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $254,978 | September 19, 2022 | March 31, 2023 | BARUCH, MOSHE | reporter.nih.gov |
| Blood Protein Markers of Biologic Treatment Response in Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $248,430 | April 15, 2023 | March 31, 2025 | UNGARO, RYAN | reporter.nih.gov |
| Using human intestinal organoids to model IBD pathogenesis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $242,250 | September 16, 2020 | August 31, 2022 | KLEIN, OPHIR D | reporter.nih.gov |
| Elucidating mechanisms of fibrosis associated with the Crohns disease-associated pathogenic variant in the metal transporter ZIP8 | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2024 | $240,713 | January 1, 2023 | December 31, 2025 | MELIA, JOANNA MILLER PELOQUIN | reporter.nih.gov |
| Durability of Epithelial Defects in Crohn's Disease Intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $238,500 | January 1, 2021 | December 31, 2022 | VANDUSSEN, KELLI LYNN | reporter.nih.gov |
| Gut Microbial Functions that Impact Multiplex and Non-multiplex Crohn’s Disease Risk. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $235,500 | September 15, 2025 | September 14, 2027 | CHEN, LEA A | reporter.nih.gov |
| Heart rate variability as a modifiable biomarker of clinical symptoms and psychological functioning in pediatric patients with inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 | $234,750 | August 15, 2023 | June 30, 2025 | REED, BONNEY | reporter.nih.gov |
| The role of sulfidogenic microbes in quiescent Crohn’s disease with persistent symptoms | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $234,000 | April 1, 2024 | March 31, 2027 | LEE, ALLEN A | reporter.nih.gov |
| Microbiota-gamma delta IEL-Paneth cell axis in host antimicrobial response | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $228,017 | June 1, 2022 | February 28, 2023 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| Structural Studies of the Potassium Channel KCa3.1 | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $211,875 | January 31, 2020 | December 31, 2022 | HUBBARD, STEVAN R. | reporter.nih.gov |
| Innate and Adaptive Immune Consequences of Necroptosis | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $211,875 | June 17, 2020 | May 31, 2022 | BLANDER, JULIE MAGARIAN | reporter.nih.gov |
| Microbiota-gamma delta IEL-Paneth cell axis in host antimicrobial response | NIH | National Institute of Allergy and Infectious Diseases | 2023 | $210,490 | June 1, 2022 | May 31, 2025 | EDELBLUM, KAREN LEIGH | reporter.nih.gov |
| Defining mechanisms of perianal fistula inception in African and European ancestry Crohn's disease patients | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2024 | $197,696 | July 1, 2021 | June 30, 2025 | LEVANTOVSKY, RACHEL | reporter.nih.gov |
| Skeletal Health and Bone Marrow Composition in Adolescents with Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $197,640 | August 4, 2023 | May 31, 2027 | GORDON, REBECCA JUDITH | reporter.nih.gov |
| Harnessing Microbial-Metabolite Signals to Guide Endoscopic and Transmural Healing for Pediatric Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $194,172 | August 1, 2025 | April 30, 2030 | COLMAN, RUBEN | reporter.nih.gov |
| Role of mucin sulfation and sulfation-specific adhesins in AIEC colonization | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $193,742 | April 1, 2020 | March 31, 2023 | KRACHLER, ANNE-MARIE | reporter.nih.gov |
| Communicating Intestinal Inflammation to the Brain in Alzheimer's Disease | NIH | National Institute on Aging | 2022 | $191,199 | September 1, 2020 | August 31, 2024 | COMBS, COLIN K | reporter.nih.gov |
| Microbiome Induced Epigenetic Changes in Intestinal Inflammation and Necrotizing Enterocolitis | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $190,762 | June 17, 2020 | May 31, 2023 | PAMMI, MOHAN | reporter.nih.gov |
| Functional Molecular Investigation of Inflammatory Bowel Disease (IBD) Risk Variants | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $189,000 | March 18, 2021 | May 31, 2022 | MARSON, ALEXANDER | reporter.nih.gov |
| T Cell Co-stimulation and the Resistance of Regulatory T cells to Gut Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $185,625 | March 1, 2019 | February 28, 2023 | MAYNARD, CRAIG L | reporter.nih.gov |
| Anticoagulant use, safety, and effectiveness for venous thromboembolism prevention in inflammatory bowel disease patients | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $183,886 | September 1, 2021 | July 31, 2023 | DAWWAS, GHADEER K. | reporter.nih.gov |
| Elucidating the role of the microbiome in inducing gut permeability and inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $181,500 | January 1, 2022 | August 21, 2023 | CHAUDHARI, SNEHAL N. | reporter.nih.gov |
| The role of local iron homeostasis in inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $177,809 | August 6, 2021 | July 31, 2022 | BESSMAN, NICHOLAS J. | reporter.nih.gov |
| New computational, transcriptional, and genome editing approaches to the biology of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $172,745 | September 19, 2018 | May 31, 2023 | GIBSON, GREGORY C | reporter.nih.gov |
| Generation and characterization of a humanized mouse model of Crohn's disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $167,500 | April 1, 2021 | March 31, 2023 | ROULIS, MANOLIS | reporter.nih.gov |
| Differential impact of smoking on the transcriptome and epigenome in Crohn's disease and ulcerative colitis" | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $167,500 | September 15, 2020 | August 31, 2023 | ANANTHAKRISHNAN, ASHWIN N | reporter.nih.gov |
| The role of HMGB1 in gut antimicrobial defense and the pathophysiology of inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $166,212 | July 1, 2017 | June 30, 2023 | MESSER, JEANNETTE SOPHIA | reporter.nih.gov |
| Modulation of gut bacteria-derived host metabolites | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $165,780 | March 8, 2018 | July 31, 2021 | DODD, DYLAN | reporter.nih.gov |
| Regulation of Experimental Colitis by Enteric Neurons | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2022 | $165,280 | April 15, 2021 | March 31, 2023 | HOTTA, RYO | reporter.nih.gov |
| The role of Axl signaling in intestinal fibrosis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $163,825 | February 1, 2025 | November 30, 2029 | STEINER, CALEN ANDREW | reporter.nih.gov |
| Aging lymphocytes: senescence programs in lymphocytes relevant to human inflammatory bowel disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $163,614 | January 4, 2023 | November 30, 2027 | GONZALEZ SALGADO, MICHELLE M | reporter.nih.gov |
| Microbe dependent mechanisms that antagonize intestinal injury repair | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $161,206 | June 1, 2023 | May 31, 2027 | NEWHALL, KEVIN PRESCOTT | reporter.nih.gov |
| Interaction of Mesenteric Adipose Tissue Physiology, Expansion, and Inflammation with Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $160,757 | June 1, 2023 | February 28, 2028 | GLINIAK, CHRISTY M | reporter.nih.gov |
| Mechanisms underlying exacerbation of inflammatory bowel disease by diabetes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $152,374 | April 1, 2022 | March 31, 2024 | FRANCIS-STREAM, KENDRA LEIGH | reporter.nih.gov |
| PROTACs Regulating HIF in Mucosal Inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2025 | $151,643 | April 11, 2025 | March 31, 2030 | ORNELAS SANCHEZ, ALFREDO | reporter.nih.gov |
| The Interplay of Host Genetic Variation and the Gut Microbiome in Crohn's Disease | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $145,246 | August 17, 2023 | August 16, 2027 | NIRMALAN, SHREYA | reporter.nih.gov |
| Enhancing Health Literacy in Surgery (EHLIS) to Eliminate Surgical Disparities for African-Americans with Inflammatory Bowel Disease (IBD) | NIH | National Institute on Minority Health and Health Disparities | 2021 | $137,559 | August 1, 2019 | August 31, 2022 | CHU, DANIEL I | reporter.nih.gov |
| Investigating the Role of IL-23R in Mucosal Regulatory T Cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $129,750 | July 10, 2020 | April 30, 2022 | GOETTEL, JEREMY ALLEN | reporter.nih.gov |
| Role of regulatory T cell glucocorticoid-induced leucine zipper (GILZ) in the chronically inflamed intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $120,750 | July 13, 2020 | April 30, 2023 | GOODMAN, WENDY ANN | reporter.nih.gov |
| Proinflammatory properties of Paneth cells in intestinal inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2023 | $103,684 | June 1, 2021 | May 31, 2024 | SPENCER, PAIGE NICOLE | reporter.nih.gov |
| Stress Induced Inflammation and Dysbiosis in a Mouse Model of Crohn's Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $102,788 | August 1, 2019 | July 31, 2023 | GOMEZ-NGUYEN, ADRIAN S | reporter.nih.gov |
| The impact of dysbiosis and the IL-12/23 signaling axis on IBD-associated bone loss. | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $99,030 | February 1, 2019 | January 31, 2023 | PEEK, CHRISTOPHER THOMAS | reporter.nih.gov |
| Agonism of DR3 for Enhanced Treg Cell Function in IBD | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $94,880 | February 1, 2019 | January 31, 2023 | DEAN, EMMA C | reporter.nih.gov |
| Elucidating the role of Myosin 5b in microvilli assembly and in the setting of inflammation | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2024 to 2025 | $89,960 | April 1, 2024 | March 31, 2027 | DOOLEY, SARAH A | reporter.nih.gov |
| Influence of gut microbiota strain variation on mucosal T-cell phenotype | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $85,271 | August 1, 2021 | January 31, 2023 | SPINDLER, MATTHEW PAUL | reporter.nih.gov |
| Bacterial, Viral, and Host Interactions in the Pathogenesis of Inflammatory Bowel Disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $80,942 | July 1, 2022 | June 30, 2023 | NEWMAN, KIRA | reporter.nih.gov |
| The role of lipid reprogramming in ferroptotic cell death in inflammatory bowel disease (IBD) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2023 | $80,442 | February 1, 2022 | January 31, 2024 | HUANG, WESLEY WEIQIAO | reporter.nih.gov |
| The role of HNF4a in maintaining intestinal epithelial cell homeostasis in the presence of microbes | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $76,734 | April 1, 2020 | March 31, 2023 | KELLY, CECELIA | reporter.nih.gov |
| Transcription factors mediate postnatal neurogenesis from enteric glial cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $75,130 | June 1, 2020 | May 31, 2022 | GUYER, RICHARD A | reporter.nih.gov |
| Determining the contribution of polyamine biosynthesis to the function of group 3 innate lymphoid cells in the gastrointestinal system | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $74,938 | September 1, 2020 | April 30, 2023 | PENG, VINCENT | reporter.nih.gov |
| Microbial-derived factors regulating mucosal wound healing | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $74,519 | February 1, 2019 | June 30, 2022 | WANG, RUTH XINHE | reporter.nih.gov |
| Regulation of the mycobiota and intestinal inflammation via production of antifungal metabolites by commensal bacteria | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $70,458 | January 25, 2019 | January 24, 2022 | FIERS, WILLIAM D | reporter.nih.gov |
| Application of social cognitive theory to physical activity behavior among adults with Crohn's disease | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2023 to 2025 | $62,130 | December 4, 2023 | May 3, 2025 | NEAL, WHITNEY NICHELLE | reporter.nih.gov |
| Alcohol, bacterial dysbiosis, and inflammation during colitis | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 | $51,036 | December 1, 2018 | November 30, 2021 | KUPRYS, PAULIUS | reporter.nih.gov |
| Mechanisms of Transcriptional Regulation by MTG16 in the Intestine | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $51,036 | September 1, 2018 | April 30, 2023 | BROWN, RACHEL ELIZABETH | reporter.nih.gov |
| Elucidating the molecular mechanisms underlying ligand-dependent REV-ERB activity in Th17 cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 to 2022 | $42,143 | January 1, 2021 | April 1, 2022 | MOSURE, SARAH | reporter.nih.gov |
| Regulation of Intestinal Innate Immunity by Speckled Protein 140 | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $39,387 | August 1, 2021 | July 31, 2022 | FRASCHILLA, ISABELLA | reporter.nih.gov |
| The Regulatory Role of PIRB in CD4+ Th17 Mediated Colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $38,036 | March 5, 2020 | March 4, 2023 | UDDIN, JAZIB NASEER | reporter.nih.gov |
| Radiomics-based Risk Prediction for Therapy Selection in Crohn’s Disease via MRI | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $35,272 | September 1, 2022 | May 31, 2023 | CHIRRA, PRATHYUSH V | reporter.nih.gov |
| Elucidating the molecular mechanisms underlying ligand-dependent REV-ERB activity in Th17 cells | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 | $24,646 | January 1, 2021 | December 31, 2022 | MOSURE, SARAH | reporter.nih.gov |
| The role of host-derived reactive oxygen species in the outgrowth of Escherichia coli during non-infectious colitis | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2021 | $11,827 | April 1, 2020 | June 11, 2021 | CHANIN, RACHAEL | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Icahn School of Medicine at Mount Sinai | New York, NY | 15 | $19.7 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 16 | $14.4 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 9 | $11.9 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 12 | $9.8 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 8 | $9.7 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 10 | $9.4 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 5 | $9.1 million | 0 | $0 |
| Connecticut Children's Medical Center | Hartford, CT | 2 | $8.8 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 6 | $8.7 million | 0 | $0 |
| Broad Institute, Inc. | Cambridge, MA | 2 | $7.7 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 8 | $7.7 million | 0 | $0 |
| Emory University | Atlanta, GA | 5 | $6.7 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 6 | $6.5 million | 0 | $0 |
| Washington University | Saint Louis, MO | 7 | $6 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 3 | $4.6 million | 0 | $0 |
| University of Texas Med BR Galveston | Galveston, TX | 4 | $4.6 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 4 | $4.4 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 5 | $4 million | 0 | $0 |
| University of South Carolina at Columbia | Columbia, SC | 2 | $3.8 million | 0 | $0 |
| Duke University | Durham, NC | 7 | $3.7 million | 0 | $0 |
| Dartmouth-Hitchcock Clinic | Lebanon, NH | 3 | $3.7 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 4 | $3.6 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 2 | $3.4 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 2 | $3.2 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 3 | $3.1 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 2 | $3 million | 0 | $0 |
| Avexegen Therapeutics, Inc. | Porter Ranch, CA | 1 | $2.9 million | 0 | $0 |
| Georgia State University | Atlanta, GA | 2 | $2.8 million | 0 | $0 |
| Stanford University | Stanford, CA | 3 | $2.7 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 4 | $2.7 million | 0 | $0 |
| University of California at Davis | Davis, CA | 4 | $2.5 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 2 | $2.5 million | 0 | $0 |
| Chromatan Corporation | Dedham, MA | 1 | $2.5 million | 0 | $0 |
| Epicypher, Inc. | Research Triangle Park, NC | 1 | $2.3 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 4 | $2.3 million | 0 | $0 |
| Montreal Heart Institute | Montreal | 1 | $2.2 million | 0 | $0 |
| Sinai Health System | Toronto | 2 | $2.1 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 2 | $2.1 million | 0 | $0 |
| Children's Research Institute | Washington, DC | 1 | $2.1 million | 0 | $0 |
| Fzata, Inc. | Halethorpe, MD | 1 | $2.1 million | 0 | $0 |
| Rutgers University Newark | Newark, NJ | 2 | $2 million | 0 | $0 |
| Scripps Florida | Jupiter, FL | 4 | $2 million | 0 | $0 |
| Aviara Pharmaceuticals, Inc. | Houston, TX | 1 | $2 million | 0 | $0 |
| Altis Biosystems, Inc. | Durham, NC | 1 | $2 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 4 | $1.9 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 2 | $1.9 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 1 | $1.9 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 2 | $1.9 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 1 | $1.8 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 1 | $1.8 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 3 | $1.8 million | 0 | $0 |
| University of Florida | Gainesville, FL | 4 | $1.7 million | 0 | $0 |
| Hackensack University Medical Center | Hackensack, NJ | 1 | $1.7 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 3 | $1.7 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 5 | $1.6 million | 0 | $0 |
| University of Houston | Houston, TX | 2 | $1.6 million | 0 | $0 |
| University of Nebraska Medical Center | Omaha, NE | 1 | $1.6 million | 0 | $0 |
| Pennsylvania State Univ Hershey Med CTR | Hershey, PA | 2 | $1.5 million | 0 | $0 |
| Ohio State University | Columbus, OH | 1 | $1.4 million | 0 | $0 |
| Rise Therapeutics, LLC | Rockville, MD | 1 | $1.4 million | 0 | $0 |
| Trethera Corporation | Sherman Oaks, CA | 2 | $1.3 million | 0 | $0 |
| SUNY at Stony Brook | Stony Brook, NY | 1 | $1.2 million | 0 | $0 |
| University of Tennessee Health Sci CTR | Memphis, TN | 1 | $1.2 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 3 | $969,000 | 0 | $0 |
| Rbhs-Robert Wood Johnson Medical School | Piscataway, NJ | 2 | $890,229 | 0 | $0 |
| Thelium Therapeutics INC | San Carlos, CA | 1 | $795,004 | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 1 | $750,700 | 0 | $0 |
| Mayo Clinic Arizona | Scottsdale, AZ | 2 | $669,326 | 0 | $0 |
| Biotherapeutics, Inc. | Blacksburg, VA | 1 | $643,417 | 0 | $0 |
| Landos Biopharma, Inc. | Blacksburg, VA | 1 | $613,188 | 0 | $0 |
| Georgetown University | Washington, DC | 1 | $612,377 | 0 | $0 |
| D Biotherapeutics, LLC | Salt Lake City, UT | 2 | $601,469 | 0 | $0 |
| Oregon State University | Corvallis, OR | 1 | $516,964 | 0 | $0 |
| Benaroya Research Inst at Virginia Mason | Seattle, WA | 1 | $476,075 | 0 | $0 |
| Keybiome LLC | Eugene, OR | 1 | $456,817 | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 1 | $451,376 | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 1 | $450,842 | 0 | $0 |
| University of Maine | Orono, ME | 1 | $436,046 | 0 | $0 |
| Cornell University | Ithaca, NY | 1 | $431,750 | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 1 | $429,989 | 0 | $0 |
| Mercer University | Macon, GA | 1 | $429,545 | 0 | $0 |
| University of California-Riverside | Riverside, CA | 1 | $427,625 | 0 | $0 |
| Hawaii Pacific University | Honolulu, HI | 1 | $405,876 | 0 | $0 |
| Rbhs-New Jersey Medical School | Newark, NJ | 2 | $405,826 | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 1 | $389,671 | 0 | $0 |
| Sachi Bioworks, Inc. | Louisville, CO | 1 | $364,674 | 0 | $0 |
| Averto Medical INC | Fremont, CA | 1 | $353,509 | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 1 | $338,526 | 0 | $0 |
| Northeastern University | Boston, MA | 1 | $305,070 | 0 | $0 |
| Symberix, Inc. | Durham, NC | 1 | $304,553 | 0 | $0 |
| Abalone Bio, Inc. | Emeryville, CA | 1 | $300,241 | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 2 | $282,877 | 0 | $0 |
| Predict Health, LLC, the | Houston, TX | 1 | $280,160 | 0 | $0 |
| Promakhos Therapeutics Inc. | Somerville, MA | 1 | $271,865 | 0 | $0 |
| Pana Bio, Inc. | Houston, TX | 1 | $254,978 | 0 | $0 |
| Harvard Medical School | Boston, MA | 2 | $220,887 | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 1 | $193,742 | 0 | $0 |
| University of North Dakota Main Campus | Grand Forks, ND | 1 | $191,199 | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 1 | $190,762 | 0 | $0 |
| J. David Gladstone Institutes | San Francisco, CA | 1 | $189,000 | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 79 | $47,188,735 | 0 | $0 |
| 2024 | 79 | $38,372,804 | 0 | $0 |
| 2023 | 128 | $60,247,176 | 0 | $0 |
| 2022 | 154 | $61,411,906 | 0 | $0 |
| 2021 | 167 | $63,728,855 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.