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Data / Research funding / Arthritis

Arthritis: 1,149 NIH awards ($1.3B) to 276 organizations

1,149 NIH awards ($1.3B) in the NIH spending category Arthritis, to 276 organizations, read 2026-11-04. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 1,149 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Accelerating Medicines Partnership-Autoimmune and Immunologic Disease Tissue Research CoreNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$19,601,747March 23, 2022December 31, 2026GUTHRIDGE, JOEL MARVINreporter.nih.gov
EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$19,316,294January 1, 2021July 31, 2026FAVA, MAURIZIOreporter.nih.gov
Center for Addiction and Disease Risk ExacerbationNIHNational Institute of General Medical Sciences2021 to 2025$12,487,946August 1, 2019July 31, 2029MONTI, PETER M.reporter.nih.gov
Mapping the joint-nerve interactome of the kneeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$11,877,917September 23, 2022August 31, 2027MALFAIT, ANNE-MARIEreporter.nih.gov
Center for Musculoskeletal Disease Research (CMDR)NIHNational Institute of General Medical Sciences2021 to 2025$11,683,826February 16, 2018January 31, 2028O'BRIEN, CHARLES Areporter.nih.gov
Innervation of the knee and TMJNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$10,814,779September 23, 2022August 31, 2027ALLEN, KYLE Dreporter.nih.gov
Increasing the Efficiency of RE-JOIN Through Data Sharing and IntegrationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$10,788,004September 23, 2022July 31, 2027LEE, BRENDANreporter.nih.gov
A sequenced-strategy for improving outcomes in patients with knee osteoarthritis painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$10,487,739September 25, 2019August 31, 2025CAMPBELL, CLAUDIA MICHELLEreporter.nih.gov
CLINICAL STUDIES MANAGEMENT AND SUPPORT (CSMS) - SOLE SOURCE BRIDGE CONTRACTNIHNational Heart, Lung, and Blood Institute2021 to 2024$8,078,483September 30, 2021January 24, 2025YOU, HUIQINGreporter.nih.gov
The Osteoarthritis Prevention Study (TOPS)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$7,779,027August 10, 2023July 31, 2028MESSIER, STEPHEN Preporter.nih.gov
Daily & Localized NSAID Sonophoresis for Symptomatic Treatment of Knee OsteoarthritisNIHNational Institute on Aging2021 to 2025$7,422,310September 20, 2024May 31, 2027LEWIS, GEORGE KENNETHreporter.nih.gov
Clinical-Translational Studies in Skin, Lung, and Vascular Complications in Systemic SclerosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$6,366,452September 20, 2022August 31, 2027LAFYATIS, ROBERT A.reporter.nih.gov
Deciphering the Genomics of Gene Network Regulation of T Cell and Fibroblast States in Autoimmune InflammationNIHNational Human Genome Research Institute2021 to 2025$6,348,798August 20, 2021May 31, 2027LESLIE, CHRISTINA Sreporter.nih.gov
Phase II trial of GM-CSF/sargramostim in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$6,265,868February 1, 2021November 30, 2026POTTER, HUNTINGTONreporter.nih.gov
Treat-to-Target Serum Urate versus Treat-to-Avoid Symptoms in Gout: A Randomized Controlled Trial (TRUST)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$5,795,791September 1, 2023July 31, 2028CHOI, HYON Kreporter.nih.gov
Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic TrialNIHNational Center for Complementary & Integrative Health2024 to 2025$5,587,756May 19, 2023August 31, 2028WANG, CHENCHENreporter.nih.gov
Structure-Function Analysis of Mxra8 Interaction with AlphavirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,414,348June 1, 2019July 31, 2029DIAMOND, MICHAEL Sreporter.nih.gov
Methotrexate treatment of Arthritis caused by Chikungunya virus (MARCH): A randomized controlled trial of methotrexate versus placebo in the treatment of chronic arthritis after chikungunya infectionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$5,036,160September 1, 2022August 31, 2027CHANG, AILEENreporter.nih.gov
Leveraging inter-individual differences in walking pain and impairment to elucidate whole-person mechanisms of knee osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$4,899,748September 19, 2025August 31, 2029ALTER, BENEDICT Jreporter.nih.gov
Activation of Macrophages in Human Autoimmune DiseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,710,162March 1, 2000July 31, 2029IVASHKIV, LIONEL Breporter.nih.gov
Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$4,709,163May 15, 2014August 31, 2023ZHANG, BINreporter.nih.gov
Chemical probes to decipher PAD biologyNIHNational Institute of General Medical Sciences2021 to 2025$4,690,000June 1, 2016May 31, 2026THOMPSON, PAUL Rreporter.nih.gov
PANDA-MSD: Predictive Analytics via Networked Distributed Algorithms for Multi-System DiseasesNIHNational Center for Advancing Translational Sciences2022 to 2025$4,670,835August 5, 2022May 31, 2027CHEN, YONGreporter.nih.gov
Network modeling as a unified framework to understand inter-individual differences in chronic musculoskeletal painNIHNational Center for Complementary & Integrative Health2025$4,649,740August 15, 2025July 31, 2029SIKDAR, SIDDHARTHAreporter.nih.gov
Monitoring of disease-induced skin VOC patterns from handheld and wearable chemical sensorsNIHNational Center for Advancing Translational Sciences2022 to 2025$4,608,903June 22, 2022May 31, 2027DAVIS, CRISTINA ELIZABETHreporter.nih.gov
Development of the INI-4001 and INI-2002 adjuvants within the context of a vaccine to prevent Lyme disease.NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$4,583,801September 30, 2018September 29, 2024EVANS, JAYreporter.nih.gov
Clinical Optimization of Ultrasonic Drug Delivery Technologies for US Veteran Populations that Experience Health Disparities with Arthritis and Chronic PainNIHNational Institute on Minority Health and Health Disparities2023 to 2025$4,518,543September 14, 2020February 28, 2026LEWIS, GEORGE KENNETHreporter.nih.gov
AIM-for-RANIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$4,499,382March 22, 2022December 31, 2026ANOLIK, JENNIFER HOWITTreporter.nih.gov
Small molecule targeting an epigenetic regulator for the treatment of osteoarthritisNIHNational Institute on Aging2021 to 2024$4,178,124September 30, 2021May 2, 2025ADORNO, MADDALENAreporter.nih.gov
Elucidating Factors Contributing to Disparities in Neurobiological Vulnerabilities and Alzheimers Disease and Related Dementias RiskNIHNational Institute on Aging2021 to 2023$4,137,397April 1, 2009February 28, 2025FILLINGIM, ROGER Breporter.nih.gov
Molecular basis of bioelectronic medicineNIHNational Institute of General Medical Sciences2021 to 2025$3,937,630May 1, 2016April 30, 2027TRACEY, KEVIN Jreporter.nih.gov
ELLIPSS: ELucidating the Landscape of Immunoendotypes in Psoriatic Skin and SynoviumNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,900,002March 21, 2022December 31, 2026RITCHLIN, CHRISTOPHER TREVORreporter.nih.gov
Osteoarthritis Progression And Sensory Pathway AlterationsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,899,677May 1, 2013July 31, 2029MALFAIT, ANNE-MARIEreporter.nih.gov
RESOURCE BASED CENTER FOR MUSCULOSKELETAL BIOLOGY AND MEDICINENIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,860,791April 15, 2019June 30, 2029SILVA, MATTHEW Jreporter.nih.gov
Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Stopping TrialNIHNational Eye Institute2021 to 2023$3,733,343May 1, 2019April 30, 2026ACHARYA, NISHAreporter.nih.gov
CNS Pain Mechanisms in Early Rheumatoid Arthritis: Implications for the Acute to Chronic Pain TransitionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,704,355July 1, 2013April 30, 2027LEE, YVONNE CLAIREreporter.nih.gov
Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,700,281March 22, 2022December 31, 2026BRENNER, MICHAEL B.reporter.nih.gov
Rheumatoid Arthritis-Related Autoantibodies, Articular Inflammation, and RA-Associated Interstitial Lung DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,692,582September 27, 2021June 30, 2027SPARKS, JEFFREY ANDREWreporter.nih.gov
ADalimumab Vs. conventional ImmunoSupprEssion for uveitis(ADVISE) TrialNIHNational Eye Institute2021 to 2022$3,613,158September 30, 2018August 31, 2025HOLBROOK, JANET T.reporter.nih.gov
Peripheral blood mononuclear cell epigenetic associations in and biomarkers for knee osteoarthritis development and progressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,596,032June 16, 2020August 31, 2028JEFFRIES, MATLOCKreporter.nih.gov
Cannabidiol for postoperative Opioid Reduction in primary total Knee arthroplasty – a randomized, 2x2 factorial, double-blind, placebo-controlled clinical trial (The CORK trial)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$3,579,362September 18, 2023August 31, 2028BRUMMETT, CHAD Mreporter.nih.gov
Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal BiomechanicsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,536,892July 14, 2016June 30, 2027MAJUMDAR, SHARMILAreporter.nih.gov
Insights Into Immune-Related Diseases Born from Population GenomicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,513,383July 6, 2010July 31, 2030NORMAN, PAUL JOHNreporter.nih.gov
Biomechanical and Biological Predictors of Cartilage Health Following Meniscus InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,493,420April 5, 2021March 31, 2026MCNULTY, AMY Lreporter.nih.gov
Studies on gut microbiome-joint connections in arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,412,637April 1, 2021February 28, 2027ZUSCIK, MICHAEL Jreporter.nih.gov
The Impact of the Bone Marrow Niche's Immune Privilege on Psoriatic ArthritisNIHNational Institute of Allergy and Infectious Diseases2025$3,406,145August 8, 2025July 31, 2029FUJISAKI, JOJIreporter.nih.gov
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL ReconstructionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,403,884August 1, 2018July 31, 2025SPINDLER, KURT PAULreporter.nih.gov
Innovative modeling of the biopsychosocial model in animals: Validation of outcomes for assessing emotional and cognitive domains affected by naturally-occurring chronic pain in dogsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$3,320,159September 18, 2024August 31, 2027GRUEN, MARGARET ELIZABETHreporter.nih.gov
Microbial Determinants of Excessive Inflammation and Severe Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2025$3,315,179September 19, 2025August 31, 2029STRLE, KLEMENreporter.nih.gov
Impact of Registry Use on Quality and Outcomes in Rheumatology (QORA)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,312,228July 16, 2021May 31, 2027SCHMAJUK, GABRIELAreporter.nih.gov
Wnt7a-Mediated Competence to Resist Osteoarthritis ProgressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,282,434February 15, 2021January 31, 2027ZENG, LIreporter.nih.gov
Unmodified and Post Translationally Modified CD4+ and CD8+ T cell Epitopes in Rheumatoid ArthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$3,237,408September 30, 2019September 29, 2023BENTON, RYANreporter.nih.gov
Gut Microbiota Modulation of Chikungunya Virus Infection and PathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,216,725April 1, 2021March 31, 2027DIAMOND, MICHAEL Sreporter.nih.gov
Psychometric Reliability and Validity for Behavioral Metrics of Osteoarthritic Pain in HorsesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$3,196,061September 19, 2024August 31, 2027ALLEN, KYLE Dreporter.nih.gov
Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRINIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$3,194,922July 16, 2019June 30, 2025LI, XIAOJUANreporter.nih.gov
VISTA is a negative checkpoint regulator of innate immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,194,465May 6, 2020April 30, 2025SKOPELJA-GARDNER, SLADJANAreporter.nih.gov
Is the gut important in multiple joint osteoarthritis? A multimodal investigation in humans and pet dogsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,176,745August 5, 2022June 30, 2027NELSON, AMANDA Ereporter.nih.gov
Multiparametric Mapping of Knee Joint with Magnetic Resonance FingerprintingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,138,468February 1, 2021August 31, 2027REGATTE, RAVINDERreporter.nih.gov
Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$3,098,703August 12, 2022June 30, 2027KWOH, C KENTreporter.nih.gov
Investigating Mucosal Breaks in the Initiation and Progression of Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,091,101June 23, 2021April 30, 2026ROBINSON, WILLIAM Hreporter.nih.gov
Designing Novel MR Imaging Tools to Quantify Lower-Limb Exercise Adaptations in Knee OsteoarthritisNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$2,997,092September 20, 2003April 30, 2028GOLD, GARRY Ereporter.nih.gov
Genetically-engineered stem cells for self-regulating arthritis therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,983,611April 1, 2022March 31, 2027GUILAK, FARSHIDreporter.nih.gov
Proteomic analysis of hydroxychloroquine prevention trials in T1D, RA and SLENIHNational Institute of Allergy and Infectious Diseases2023 to 2024$2,978,715August 18, 2023July 31, 2028BUCKNER, JANE HOYTreporter.nih.gov
Role of Systemic Inflammation in Cognitive Decline: Rheumatoid Arthritis as a PrototypeNIHNational Institute on Aging2021 to 2024$2,977,796September 30, 2020May 31, 2026MYASOEDOVA, ELENAreporter.nih.gov
A Novel IL-35 Expressing Probiotic Platform for Inducing Allergen Specific ToleranceNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,952,468May 1, 2020June 30, 2025FANGER, NEIL Areporter.nih.gov
Metabolic Regulation of Articular Cartilage and Joint HomeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,949,056July 8, 2021June 30, 2027O'KEEFE, REGIS Jreporter.nih.gov
Optimizing the value of pain management in knee OA patients with comorbiditiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,947,711August 1, 2018March 31, 2029LOSINA, ELENAreporter.nih.gov
Rheumatoid Arthritis-associated Parenchymal Lung Disease: Clinical and Molecular PhenotypesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,937,551April 15, 2022March 31, 2027WASHKO, GEORGE Rreporter.nih.gov
Human Genetic Variation and DiseaseNIHNational Institute of General Medical Sciences2021 to 2025$2,936,758July 22, 2016June 30, 2027JORDE, LYNNreporter.nih.gov
Knee Arthroplasty Activity Trial (KArAT)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,935,459September 23, 2022August 31, 2027LOSINA, ELENAreporter.nih.gov
Multi-Vendor Multi-Site Novel Accelerated MRI RelaxometryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,931,322May 1, 2020April 30, 2027LI, XIAOJUANreporter.nih.gov
NOVEL METABOLITE AND MICROBIOTA PATHWAYS FOR HYPERURICEMIA AND GOUTNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,924,301September 20, 2013February 28, 2027CHOI, HYON Kreporter.nih.gov
A Novel Immunologically Enhanced Probiotic for Treating Rheumatoid ArthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,922,693February 23, 2021January 31, 2025FANGER, GARYreporter.nih.gov
Molecular Pathways of Pain Generation in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,896,087February 1, 2011June 30, 2026MALFAIT, ANNE-MARIEreporter.nih.gov
The role of cytotoxic T cells in rheumatoid arthritis pathogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,877,343September 1, 2021August 31, 2026ANDRADE, FELIPEreporter.nih.gov
The mechanistic control of bone quality and joint crosstalk by osteocytesNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,877,278March 20, 2009May 31, 2026HERNANDEZ, CHRISTOPHER JOHNreporter.nih.gov
Cannabinoid interactions with central and peripheral pain mechanisms in osteoarthritis of the kneeNIHNational Center for Complementary & Integrative Health2021 to 2024$2,864,374August 1, 2020May 31, 2026HARTE, STEVEN EDWARDreporter.nih.gov
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signalsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,853,080July 10, 2020June 30, 2026LUND, FRANCES E.reporter.nih.gov
Molecular Determinants of Usual Interstitial Pneumonia (UIP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,826,957April 1, 2022March 31, 2027SCHWARTZ, DAVID ALBERTreporter.nih.gov
Rheumatoid Arthritis and the Risk of Cardiovascular Disease: Biomarkers Risk Prediction and Underlying MechanismsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,807,438June 15, 2022May 31, 2027SOLOMON, DANIEL HALreporter.nih.gov
Monitoring Disease in LupusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,798,512March 8, 2019June 30, 2029MOHAN, CHANDRAreporter.nih.gov
Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional stateNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,784,187August 2, 2013March 31, 2026RAYCHAUDHURI, SOUMYAreporter.nih.gov
Simultaneous Imaging of Tissue Biochemistry and Metabolism associated with Biomechanics in Patella Femoral Joint OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,778,600March 15, 2022February 28, 2027SOUZA, RICHARD BRIANreporter.nih.gov
NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of InflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,777,000June 1, 2023November 30, 2025KARIN, MICHAELreporter.nih.gov
Understanding the mechanisms by which weight change affects progression of knee osteoarthritis in obese and overweight individuals: An analysis of the Osteoarthritis Initiative DatasetNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,775,126April 1, 2021October 31, 2026LINK, THOMAS Mreporter.nih.gov
Ultra-Fast Knee MRI with Deep LearningNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,771,921April 1, 2021March 31, 2027MAJUMDAR, SHARMILAreporter.nih.gov
FoxO transcription factors in joint aging and osteoarthritis pathogenesisNIHNational Institute on Aging2021 to 2025$2,771,759May 15, 2018May 31, 2028LOTZ, MARTIN Kreporter.nih.gov
Supramolecular biomaterials for tuning the inflammatory properties of the complement systemNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,759,425June 1, 2022May 31, 2027COLLIER, JOEL Hreporter.nih.gov
The Role of Creb5 in Maintaining Synovial Joint HomeostasisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,724,113July 28, 2022May 31, 2027LASSAR, ANDREW BRUCEreporter.nih.gov
Bridging clinical trial and real-world data via machine learning to advance rheumatoid arthritis treatment strategiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,718,736July 1, 2022June 30, 2027LIAO, KATHERINE PHOENIXreporter.nih.gov
The IL-23/IL-17 Axis in Inflammatory ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,710,108June 1, 2021November 30, 2026LEVY, DANreporter.nih.gov
Macrophage Heterogeneity in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,660,867April 15, 2022February 28, 2027WINTER, DEBORAH RACHELLEreporter.nih.gov
Role of GRAIL in B cell tolerance and B-cell mediated inflammationNIHNational Institute of Allergy and Infectious Diseases2025$2,630,572August 1, 2025July 31, 2029NURIEVA, ROZA INSAFETDINOVNAreporter.nih.gov
Establishing a Single-Cell Proteomic Atlas for Normal and Osteoarthritic Articular CartilageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,626,425May 17, 2021March 31, 2026BHUTANI, NIDHIreporter.nih.gov
Image-guided, robot-assisted reduction of joint dislocation in orthopaedic surgeryNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,590,549September 1, 2021May 31, 2026UNERI, ALIreporter.nih.gov
Multi-modal Tracking of In Vivo Skeletal Structures and ImplantsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$2,582,151April 15, 2022March 31, 2026CRISCO, JOSEPH Jreporter.nih.gov
Rapid Low-Cost Quantitative 3D MRI and Gait Assessment of the KneeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,579,635August 15, 2020June 30, 2025HARGREAVES, BRIAN ANDREWreporter.nih.gov
Micro-TeACH (Microbiome Technology and Analytic Center Hub)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,568,320March 10, 2022December 31, 2026SCHER, JOSE U.reporter.nih.gov
Bioinspired Mechanically Stiff Hydrogels for Osteochondral Tissue RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,563,338July 25, 2016March 31, 2027BRYANT, STEPHANIE Jreporter.nih.gov
The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,563,053August 1, 2020July 31, 2025HUARD, JOHNNYreporter.nih.gov
Role of ZBP1 in pathogenesis of Salmonella biofilmsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,527,208May 11, 2023April 30, 2028BALACHANDRAN, SIDDHARTHreporter.nih.gov
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee ArthroplastyNIHNational Institute on Aging2025$2,526,074September 30, 2023August 31, 2028BRUEHL, STEPHENreporter.nih.gov
Immunologic Mechanisms and Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,525,449July 1, 1985July 31, 2030GRAVALLESE, ELLEN Mreporter.nih.gov
Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled TrialNIHNational Cancer Institute2022 to 2025$2,513,680June 1, 2022May 31, 2027RINI, CHRISTINEreporter.nih.gov
Neural and Energetic Drivers of Performance and Perceived Fatigability in Older AdultsNIHNational Institute on Aging2022 to 2025$2,501,429September 15, 2022May 31, 2027ROSANO, CATERINAreporter.nih.gov
A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)NIHNational Institute on Aging2024 to 2025$2,500,587September 15, 2024August 31, 2029FANNING, JASONreporter.nih.gov
Continuation Application for the development of Integrated continuous and single-use (ICS) bioproduction platform (Phase IIB)NIHNational Institute of General Medical Sciences2022 to 2023$2,495,306January 1, 2016March 31, 2024SHINKAZH, OLEGreporter.nih.gov
Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive EnzymeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,493,979April 1, 2022March 31, 2027ALLEN, KYLE Dreporter.nih.gov
Integrative Omics analysis of human cartilage in aging and osteoarthritisNIHNational Institute on Aging2021 to 2024$2,482,844January 15, 2016May 31, 2026LOTZ, MARTIN Kreporter.nih.gov
Deciphering multi-scale differentiation and patterning cues driving whole craniofacial joint regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,462,001September 6, 2022August 31, 2027SMEETON, JOANNA MARJORIEreporter.nih.gov
A Novel Immunological-Directed Biotherapy for Treating Rheumatoid ArthritisNIHNational Institute on Aging2023 to 2025$2,434,680September 4, 2023June 30, 2027FANGER, GARYreporter.nih.gov
Rapid Quantitative Assessment of Knee Joint with Compressed SensingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,428,622August 3, 2020July 31, 2026REGATTE, RAVINDERreporter.nih.gov
Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,419,724March 18, 2022December 31, 2026RAYCHAUDHURI, SOUMYAreporter.nih.gov
CaMKK2 Signaling in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,408,999March 13, 2020January 31, 2026SANKAR, UMAreporter.nih.gov
The Effects of Visit Characteristics on Patient-Clinician Interactions and Health Outcomes in Knee OsteoarthritisNIHNational Institute on Aging2023 to 2025$2,402,726September 1, 2023June 30, 2028DOSSETT, MICHELLE Lreporter.nih.gov
OpenSim Enhancements to Enable Computational Design of Personalized Treatments for Movement ImpairmentsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,391,188September 6, 2021May 31, 2026FREGLY, BENJAMIN Jreporter.nih.gov
Demographic Distribution of Hand Joint SpaceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$2,373,086September 27, 2021August 31, 2024KWOH, C KENTreporter.nih.gov
Regulation of Intracellular SignalingNIHNational Institute of General Medical Sciences2021 to 2025$2,370,356June 1, 2019February 28, 2029IIJIMA, MIHOreporter.nih.gov
Deconstructing Cartilage Mechanotransduction by Piezo ChannelsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,369,902June 2, 2021July 31, 2025GUILAK, FARSHIDreporter.nih.gov
Enhancing modulation Effect of Baduanjin through Non-invasive Neuromodulation for knee OsteoarthritisNIHNational Center for Complementary & Integrative Health2023 to 2025$2,363,880August 4, 2023May 31, 2028KONG, JIANreporter.nih.gov
Post-Initiation control of transcription in inflammatory macrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,363,024December 23, 2019November 30, 2025ROGATSKY, INEZreporter.nih.gov
Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain (DIRECTPain)NIHNational Institute of Nursing Research2022 to 2025$2,358,097September 21, 2022June 30, 2027SORGE, ROBERTreporter.nih.gov
Imaging of Joint Response to Physiological Stress with Age, Sex and in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,351,319May 1, 2022February 28, 2027KOGAN, FELIKSreporter.nih.gov
Role of human innate immune mutations in loss of tolerance to Borrelia burgdorferiNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,344,769September 8, 2020August 31, 2025HU, LINDEN Treporter.nih.gov
Transcriptional control of growth plate chondrocytesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,317,204May 15, 2022April 30, 2027LEFEBVRE, VERONIQUE Mreporter.nih.gov
Identification of key regulators in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,309,449August 1, 2014April 30, 2026WANG, WEIreporter.nih.gov
MASPs as therapeutic targets in complement-mediated diseasesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,302,777March 18, 2020February 28, 2025SONG, WENCHAOreporter.nih.gov
Joint Pain on a Chip: Mechanistic Analysis Therapeutic Targets and an Empirical Strategy for Personalized Pain ManagementNIHNational Center for Advancing Translational Sciences2021$2,287,391September 26, 2019July 31, 2025GOLD, MICHAEL Sreporter.nih.gov
Establishing the Guma' Tinemtom to support population health research through island wisdom in GuamNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,265,237July 1, 2022March 31, 2027PAULINO, YVETTE Creporter.nih.gov
Move and Snooze: Adding insomnia treatment to an exercise program to improve pain outcomes in older adults with knee osteoarthritisNIHNational Institute on Aging2023 to 2025$2,261,590September 30, 2023June 30, 2028WHIBLEY, DANIELreporter.nih.gov
Cell Senescence Regulating Osteoarthritis Progression: Sex-dependent MechanismsNIHNational Institute on Aging2023 to 2025$2,244,684January 15, 2023November 30, 2027CHEN, QIANreporter.nih.gov
Arthroscopic Raman Monitoring of Cartilage Content for PTOA Diagnosis and Chondroregenerative Treatment ResponseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,239,693August 2, 2022May 31, 2027ALBRO, MICHAEL Breporter.nih.gov
Leveraging Community-Academic Partnerships and Social Networks to Disseminate Vaccine-Related Information and Increase Vaccine Uptake Among Black Individuals with Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$2,239,160May 10, 2022April 1, 2025RAMSEY-GOLDMAN, ROSALINDreporter.nih.gov
Roles of Collagen and Water in the Fracture Resistance of BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,220,473September 1, 2012May 31, 2027NYMAN, JEFFRY STEPHENreporter.nih.gov
Development of a metabolomics and machine learning based high-throughput screening platform for data-driven drug discoveryNIHNational Institute of General Medical Sciences2021 to 2022$2,207,584September 1, 2018January 31, 2024BORDBAR, AARASHreporter.nih.gov
Interpretation and Utility of Novel Composite Structural Endpoints of Cumulative Damage and Disease Activity in Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,206,921January 23, 2024May 31, 2026DRIBAN, JEFFREY Breporter.nih.gov
Immunologic and Clinical Sequelae after COVID-19 in Patients with Systemic Autoimmune Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,205,056February 1, 2023January 31, 2028SPARKS, JEFFREY ANDREWreporter.nih.gov
Promoting regenerative repair of aged cartilageNIHNational Institute on Aging2023 to 2025$2,189,662May 15, 2023January 31, 2028COLLINS, JOHN Areporter.nih.gov
Modification of Post-Traumatic Osteoarthritis Progression with Joint UnloadingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,182,992March 1, 2020November 30, 2025CHRISTIANSEN, BLAINE A.reporter.nih.gov
Digital Biomarkers of Post-traumatic Osteoarthritis: Toward Precision RehabilitationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,179,833September 1, 2022August 31, 2027HALILAJ, ENIreporter.nih.gov
Probing Osteoarthritis Pathogenesis by Noninvasive Imaging of Cartilage StrainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$2,176,180September 19, 2013March 31, 2025NEU, COREY Preporter.nih.gov
Targeting angiogenesis for fracture nonunion treatment under inflammatory diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,165,056September 9, 2020June 30, 2027SHEN, JIEreporter.nih.gov
Pathogenesis of Systemic Juvenile Idiopathic Arthritis-Associated Lung DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,153,155April 6, 2022February 28, 2027SCHULERT, GRANT SANFORDreporter.nih.gov
Identifying a novel pathway that regulates RA immunometabolismNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,137,878July 8, 2022June 30, 2028SHAHRARA, SHIVAreporter.nih.gov
Tissue Adhesive RNA Interference Nanoparticles to Block Progression of Posttraumatic and Spontaneous Osteoarthritis.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,136,077August 22, 2022July 31, 2027DUVALL, CRAIG LEWISreporter.nih.gov
Improvement of Animal Models for TMJ Stem Cell-Based RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,135,816July 15, 2019April 30, 2025EMBREE, MILDRED CHRISTINEreporter.nih.gov
A Bio-inspired Latent TGF-beta Conjugated Scaffold for Patient-specific Cartilage RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,133,303June 1, 2022May 31, 2027ALBRO, MICHAEL Breporter.nih.gov
Suppressing Inflammation by Blocking IKK OligomerNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,117,232February 15, 2022January 31, 2027GHOSH, GOURISANKARreporter.nih.gov
Data-Driven Learning Framework for Fast Quantitative Knee Joint MappingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,115,033July 1, 2021May 31, 2027WUST ZIBETTI, MARCELO VICTORreporter.nih.gov
Neural immunoregulation of post-traumatic autoimmunityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,111,177September 1, 2016July 31, 2027KINGERY, WADE Sreporter.nih.gov
Academic Rheumatology and Clinical ImmunologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,110,183June 1, 2021May 31, 2026ZIKHERMAN, JULIEreporter.nih.gov
Investigating monocyte dysfunction in Down SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$2,109,849July 24, 2019December 31, 2024HAMERMAN, JESSICA Areporter.nih.gov
Novel approaches to promote healing of bone loss in inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,084,763March 14, 2022February 28, 2027SHIM, JAE-HYUCKreporter.nih.gov
Intra-cartilage depot delivery of electrically-charged IL-1RA for targeting osteoarthritis-associated inflammation and catabolism in multiple joint tissuesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,062,254September 21, 2020July 31, 2026BAJPAYEE, AMBIKA GOELreporter.nih.gov
Engineered probiotic for the treatment of autoimmune diseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,050,291March 20, 2023February 29, 2028BEETON, CHRISTINEreporter.nih.gov
Multinuclear MRI to Assess Joint Homeostasis after Knee InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,048,056July 1, 2022November 30, 2027MADELIN, GUILLAUMEreporter.nih.gov
Brain Pathophysiology of Osteoarthritis PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$2,046,367February 1, 2019December 31, 2024APKARIAN, APKAR VANIAreporter.nih.gov
Neural Ice Technology for Treatment of PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$2,045,816August 21, 2024July 31, 2027SIDOTI, CHARLESreporter.nih.gov
Simulation and Education Tool for Physical Examinations of Orthopedic PathologiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$2,045,149July 1, 2022June 30, 2026CONDON, JOHN PAULreporter.nih.gov
Neutrophil Extracellular Traps in the Lung and Development of Rheumatoid Arthritis-Related Autoimmunity and ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,044,363February 7, 2020January 31, 2026DEMORUELLE, M. KRISTENreporter.nih.gov
Subchondral Trabecular Plate and Rod Abnormalities in Human OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,030,282June 1, 2023May 31, 2028GUO, X. EDWARDreporter.nih.gov
Genomic and Imaging Markers to Understand and Predict Progression of Joint Damage After InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,029,292August 8, 2023July 31, 2028KIRSCH, THORSTENreporter.nih.gov
Sustained Biomaterial-mediated Inhibition of R-spondin 2 to Target Pathological Wnt Signaling in Post-Traumatic OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,029,238September 15, 2022June 30, 2027HANKENSON, KURT DAVIDreporter.nih.gov
Age-related decline in endogenous pain modulation and its impact on osteoarthritis painNIHNational Institute on Aging2022 to 2025$2,028,372June 1, 2022March 31, 2027RO, JIN Yreporter.nih.gov
Immunobiology of the Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,027,343September 30, 1977July 31, 2027LENSCHOW, DEBORAH Jreporter.nih.gov
Brain-based and clinical phenotyping of pain pharmacotherapy in knee OANIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,020,563August 15, 2023July 31, 2028SCHNITZER, THOMAS JACKreporter.nih.gov
Intra-articular corticosteroid injections for symptomatic osteoarthritis: The effects of injection dose, frequency, and timing on safetyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$2,017,972September 10, 2025August 31, 2028BUTLER, ANNE MOBLEYreporter.nih.gov
Non-SteroidAl Impact on Kidney Disease Study (NSAIDS)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,009,118May 15, 2023March 31, 2028ESTRELLA, MICHELLE Mreporter.nih.gov
Revision ACL Reconstruction: A Comparative Effectiveness Treatment StudyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,009,015September 1, 2011August 30, 2029WRIGHT, RICK Wreporter.nih.gov
Elucidation of the Role of Creb5 in Synovial Joint FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$2,004,843September 18, 2019May 9, 2025LASSAR, ANDREW BRUCEreporter.nih.gov
Transcriptional Checkpoints Of Autoimmune EncephalomyelitisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,003,720December 20, 2019November 30, 2025JORDAN, MARTHA Sreporter.nih.gov
Commercialization Readiness Pilot (CRP) program support for: Ultra-sensitive, direct-from-blood, molecular detection of Borrelia infections.NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,000,000April 2, 2024March 31, 2027SINGER, ALONreporter.nih.gov
Augmented Reality Platform for Telehealth RehabilitationNIHNational Institute on Aging2023 to 2025$1,998,221June 1, 2021October 31, 2026SHIWANI, BHAWNAreporter.nih.gov
The Study of Muscle, Mobility and Aging with Knee OANIHNational Institute on Aging2021 to 2025$1,995,873September 1, 2021May 31, 2027LANE, NANCY Ereporter.nih.gov
The Role of Mechanosensation Pathways in Osteoarthritis Joint Damage and PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,990,517April 2, 2021August 31, 2026MILLER, RACHEL ELIZABETHreporter.nih.gov
Evaluation of mechanistic role of artemin/GFRα3 signaling in osteoarthritis painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,988,920May 1, 2022April 30, 2028MISHRA, SANTOSH K.reporter.nih.gov
Influence of bacterial tryptophan metabolism on inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,982,751April 10, 2019July 31, 2029KUHN, KRISTINE A.reporter.nih.gov
Advancing Hemiarthroplasty: Predicting in vivo performance of cartilage bearing systems through benchtop and ex vivo testing.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,979,272August 15, 2023July 31, 2028CRISCO, JOSEPH Jreporter.nih.gov
Molecular mechanisms of Salmonella mediated autoimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,975,400June 1, 2020May 31, 2025TUKEL, CAGLAreporter.nih.gov
Development of an automated IVD for the ultra-sensitive, direct, molecular detection of Borrelia for early Lyme DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,972,995June 15, 2020May 31, 2024SINGER, ALONreporter.nih.gov
Novel functions of Thrombin Activatable Fibrinolysis Inhibitor (TAFI)NIHNational Heart, Lung, and Blood Institute2021 to 2023$1,967,120April 1, 2020July 31, 2024MOSNIER, LAURENT OLIVIERreporter.nih.gov
Targeting the CCR6-CCL20 pathway for treatment of psoriatic joint and entheseal inflammationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,964,807September 1, 2023August 31, 2025CLARKE, WILLIAM Rreporter.nih.gov
Employing the gut microbiome to accelerate effective initiation of rheumatoid arthritis therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,960,579September 1, 2019August 31, 2025SCHER, JOSE U.reporter.nih.gov
Role of the CD47 Pathway in Rheumatoid Arthritis Pathogenesis and TreatmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,960,562September 20, 2022July 31, 2027KORMAN, BENJAMIN DOUGLASreporter.nih.gov
Biopsychosocial determinants of pediatric-onset chronic musculoskeletal painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,955,201September 19, 2025July 31, 2030KASHIKAR-ZUCK, SUSMITAreporter.nih.gov
Rapid quantification of nuclear citrullination in human neutrophilsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,952,315June 13, 2018January 31, 2023JOHNSTONE, ANDREA LYNNreporter.nih.gov
Identifying novel osteoarthritis risk genes using GWAS, chondrocyte genomics, and genome editingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,950,418September 20, 2022August 31, 2027PHANSTIEL, DOUGLAS H.reporter.nih.gov
Cellular Stress in Pain and Tissue DamageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,950,412September 10, 2025August 31, 2028ROMERO-SANDOVAL, E. ALFONSOreporter.nih.gov
Phlpp phosphatases in osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,935,825September 21, 2022August 31, 2027WESTENDORF, JENNIFER Jreporter.nih.gov
Cytokine regulation of RA synoviocyte phenotypeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,930,588September 27, 1999May 31, 2027IVASHKIV, LIONEL Breporter.nih.gov
Sialylation of TLR2 Induces Osteoclast Fusion and Th 17 differentiation During AgingNIHNational Institute on Aging2022 to 2025$1,926,073July 1, 2022March 31, 2027CAO, XUreporter.nih.gov
Role of DNA damage and cellular senescence in osteoarthritis pathophysiologyNIHNational Institute on Aging2023 to 2025$1,923,686September 30, 2023May 31, 2028DIEKMAN, BRIAN Oreporter.nih.gov
Molecular pathways of calcium pyrophosphate deposition diseaseNIHNational Institute on Aging2022 to 2025$1,916,779September 1, 2022May 31, 2027ROSENTHAL, ANN Kreporter.nih.gov
In Vivo Knee Motion and ACL Biomechanics During Dynamic ActivitiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,913,305May 1, 2014July 31, 2025DEFRATE, LOUIS E.reporter.nih.gov
Research Training in Rheumatology at Massachusetts General HospitalNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,901,968July 1, 1977June 30, 2029LUSTER, ANDREW Dreporter.nih.gov
Dysregulation of epidermal innate immune signaling as driver of Psoriatic-like arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,901,310September 15, 2025August 31, 2028RAZANI, BAHRAMreporter.nih.gov
B cell costimulatory signals in the pathogenesis of SLENIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,899,404August 1, 2019June 30, 2024JACKSON, SHAUN WILLIAMreporter.nih.gov
Effects of TNF Blockade on Human BPH/LUTSNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,899,179August 15, 2023May 31, 2028HAYWARD, SIMON Wreporter.nih.gov
Optimizing Ultrasound Regimens for Achieving Cartilage RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,896,387February 11, 2022November 30, 2026SUBRAMANIAN, ANURADHAreporter.nih.gov
Improving COVID-19 Vaccine Uptake Among Racial and Ethnic Minority Groupswith Rheumatic DiseasesNIHNational Institute on Minority Health and Health Disparities2023 to 2025$1,876,437August 17, 2023May 31, 2028DANILA, MARIA IOANAreporter.nih.gov
A self-assembled hydrogel with tunable drug release kinetics for preventing osteoarthritis in active jointsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,875,630May 1, 2021March 31, 2027JOSHI, NITINreporter.nih.gov
Combination Gene Therapy for Treatment of Canine Mucopolysaccharidosis Type INIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,867,960May 5, 2023February 29, 2028WANG, RAYMOND YU JEANGreporter.nih.gov
Regulation of T helper cell functions by aryl hydrocarbon receptorNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,865,873May 18, 2021March 31, 2026RAO, DEEPAK ANGARAreporter.nih.gov
Predicting uveitis onset in children with juvenile idiopathic arthritisNIHNational Eye Institute2021 to 2023$1,863,787September 30, 2019June 30, 2025ANGELES-HAN, SHEILA THERESEreporter.nih.gov
Cartilage Regeneration with Tunable Inflammation ResistanceNIHNational Institute on Aging2021 to 2023$1,862,105September 15, 2017May 31, 2026ESTES, BRADLEY Treporter.nih.gov
Improved Diagnostic MRI around Metallic ImplantsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,852,226February 1, 2022December 31, 2027NAYAK, KRISHNA Sreporter.nih.gov
PARTIAL MENISCECTOMY VS. NONOPERATIVE MGMT. IN MENISCAL TEAR WITH OA: AN RCTNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,851,873September 21, 2007August 31, 2025KATZ, JEFFREY NEILreporter.nih.gov
Nonaddictive opioid prodrug nanomedicine for musculoskeletal painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,851,532September 7, 2022July 31, 2027WANG, DONGreporter.nih.gov
Defining the molecular and radiologic phenotype of progressive RA-ILDNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,845,758August 1, 2023May 31, 2028LEE, JOYCE SUJINreporter.nih.gov
Hyaluronan signaling to nociceptors in inflammatory painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,845,667April 5, 2019January 31, 2024LEVINE, JON DAVIDreporter.nih.gov
Knee-Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT)NIHNational Institute on Aging2023 to 2024$1,836,814September 30, 2018November 30, 2025KREPKOVICH, EILEEN T.reporter.nih.gov
STABILITY 2: ACL Reconstruction +/- Lateral Tenodesis with Patellar vs. Quad TendonNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,826,074September 17, 2019February 28, 2026IRRGANG, JAMES JOHNreporter.nih.gov
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee ArthroplastyNIHNational Institute on Aging2023 to 2024$1,823,768September 30, 2023August 31, 2028BRUEHL, STEPHENreporter.nih.gov
Training Program/Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,820,037May 1, 2020May 31, 2030MERKEL, PETER Areporter.nih.gov
Defining the Pathogenic Contribution of High Genotypic MIF ExpressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,816,705June 1, 2021April 30, 2026BUCALA, RICHARD Jreporter.nih.gov
Translational strategies for optimizing musculoskeletal recovery after ACL injuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,813,356August 15, 2022May 31, 2027LEPLEY, LINDSEY Kreporter.nih.gov
Cell-directed gene therapy for pain recovery after surgery and inflammationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,809,441January 15, 2022December 31, 2026ROMERO-SANDOVAL, E. ALFONSOreporter.nih.gov
Self-Powered Load Sensors for Total Knee Replacement Health MonitoringNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,805,455June 1, 2022May 31, 2027TOWFIGHIAN, SHAHRZADreporter.nih.gov
Brain neural networks regulating inflammationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,802,946September 18, 2023August 31, 2028TRACEY, KEVIN Jreporter.nih.gov
Collagen-mediated approaches to improve the local delivery and hypothermic release of osteoarthritis therapeuticsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,801,687September 1, 2023July 31, 2028KIICK, KRISTI Lreporter.nih.gov
EGFR signaling in osteoarthritis and treatmentNIHNational Institute on Aging2021 to 2024$1,794,940September 30, 2020June 30, 2025QIN, LINGreporter.nih.gov
Morphological and Biomechanical Insights into the Pathophysiology of Femoroacetabular Impingement SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,794,039July 1, 2020June 30, 2027ANDERSON, ANDREW EDWARDreporter.nih.gov
Mechanistic Pharmacokinetics and PharmacodynamicsNIHNational Institute of General Medical Sciences2021 to 2023$1,792,910May 1, 2019April 30, 2025JUSKO, WILLIAM J.reporter.nih.gov
Endogenous retrovirus in joint aging and osteoarthritis developmentNIHNational Institute on Aging2023 to 2025$1,791,833August 15, 2023April 30, 2028YANG, TAOreporter.nih.gov
Genetic and Genomic Dissection of Psoriatic ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,790,366September 12, 2012June 30, 2025ELDER, JAMES TILFORDreporter.nih.gov
Intra-Articular Drug Delivery Modulating Immune Cells in Inflammatory Joint DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,782,728February 1, 2023December 31, 2028ZHANG, LIANGFANGreporter.nih.gov
Macrophages in human autoimmune tissue pathologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,780,000May 4, 2020April 30, 2026DONLIN, LAURA T.reporter.nih.gov
Regulation of chondrocyte fate and function by ECM ViscoelasticityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,772,780September 1, 2023June 30, 2028BHUTANI, NIDHIreporter.nih.gov
Translational genomics in gout: From GWAS signal to mechanismNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,771,754September 21, 2023August 31, 2028MERRIMAN, TONY Rreporter.nih.gov
Training Program in Investigative RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,767,957July 1, 1976August 31, 2026BUCALA, RICHARD Jreporter.nih.gov
Carpometacarpal Osteoarthritis: Understanding the Intersection of Muscle Mechanics, Joint Instability, and PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,766,845April 1, 2022March 31, 2027NICHOLS, JENNIFER A.reporter.nih.gov
A Multisystem Resilience Approach in the Assessment of Postsurgical Pain TrajectoriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,766,506September 14, 2023July 31, 2028BARTLEY, EMILY J.reporter.nih.gov
Role of PTPRS in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,765,973September 1, 2014March 31, 2027BOTTINI, NUNZIOreporter.nih.gov
Effect of statin intake on Non-traumatic Generalized Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,765,770September 22, 2021August 31, 2026DEMEHRI, SHADPOURreporter.nih.gov
Molecular engineering of HA-based lubricants for articular cartilageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,761,424July 21, 2023June 30, 2028VARGHESE, SHYNIreporter.nih.gov
Scientist Training in Rheumatology ResearchNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,757,460July 1, 1976June 30, 2028KNIGHT, JASONreporter.nih.gov
Regulation of Osteoclastogenesis and Arthritic Bone Resorption by RBP-JNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,755,074April 1, 2017December 31, 2028ZHAO, BAOHONGreporter.nih.gov
Cellular and humoral immunity in Lyme arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,748,421January 8, 2019June 30, 2024STEERE, ALLEN Creporter.nih.gov
Multi-Scale In Vitro 3D Tissue Model of Vascularized Bone-Cartilage InteractionsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,730,750September 21, 2017August 31, 2024ROEHM, KEVINreporter.nih.gov
MiACLR: Michigan Initiative for Anterior Cruciate Ligament RehabilitationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,730,414September 1, 2018December 31, 2024PALMIERI-SMITH, RIANN MARIEreporter.nih.gov
Deep Learning Technology for Rapid Morphological and Quantitative Imaging of Knee PathologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,726,932June 1, 2022May 31, 2027LIU, FANGreporter.nih.gov
Synovial Macrophage Transcriptional Signatures for Predicting Therapeutic EfficacyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,724,874September 18, 2019July 31, 2025PERLMAN, HARRIS Rreporter.nih.gov
Research Training in RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,722,123July 1, 1975June 30, 2026MUSTELIN, TOMAS Mreporter.nih.gov
Treating knee osteoarthritis by sPLA2 inhibitor-loaded micellar nanoparticlesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,715,893April 1, 2022March 31, 2028CHENG, ZHILIANGreporter.nih.gov
Preclinical Development of the TAK1 Inhibitor HS-276 for the Treatment of Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,709,883September 22, 2021August 31, 2024SCARNEO, SCOTTreporter.nih.gov
Preoperative perturbation training to prevent falls after total knee arthroplastyNIHNational Institute on Aging2022 to 2024$1,709,303September 1, 2022June 30, 2027FOUCHER, KHARMA CHARISSEreporter.nih.gov
The impact of sex and gender on disease progression, from developmental originsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,704,773September 10, 2020August 31, 2025PISARSKA, MARGARETAreporter.nih.gov
Immune Checkpoint Inhibition and humoral immune response in systemic autoimmunityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,697,982August 15, 2021February 28, 2027ZENG, HUreporter.nih.gov
Quantitative bone radiomics using Ultra-High Resolution CTNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,691,144July 1, 2021March 31, 2026ZBIJEWSKI, WOJCIECH BARTOSZreporter.nih.gov
ProGel Technology for Better Management of Osteoarthritis PainNIHNational Institute on Drug Abuse2021 to 2022$1,680,880May 1, 2020December 31, 2023GOLDRING, STEVENreporter.nih.gov
Randomized controlled trial evaluating an innovative community-based intervention combining group-based exercise and behavioral health skills-training for older adults with painful knee osteoarthritisNIHNational Institute on Aging2021 to 2023$1,676,006May 1, 2019April 30, 2025PATEL, KUSHANGreporter.nih.gov
Articular Cartilage Tissue Engineering with Human Pluripotent Stem CellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,673,298April 1, 2021March 31, 2027NAKAYAMA, NAOKIreporter.nih.gov
Treatment and prevention of osteoarthritis with an intra-articular disease-modifying regenerative therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,671,789September 16, 2021August 31, 2024ANGLE, SIDDHESHreporter.nih.gov
Cell-Matrix Regulation of Fibrochondrocytes in TMJ OANIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,659,762April 1, 2021March 31, 2026REED, DAVID ANDREWreporter.nih.gov
Effectiveness of the HPV Vaccine in Immunocompromised PopulationsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,654,519July 9, 2024May 31, 2029SILVERBERG, MICHAEL Jreporter.nih.gov
Rapid Three-dimensional Simultaneous Knee Multi-Relaxation MappingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,652,212July 15, 2022May 31, 2027LIU, FANGreporter.nih.gov
Biodegradable Piezoelectric Nanocomposite Scaffold with Physical Exercise to Heal Major Cartilage Defects in Large AnimalsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,650,011June 3, 2022April 30, 2027NGUYEN, THANHreporter.nih.gov
Assessment of ultrasound features of knee osteoarthritis in a population-based community cohortNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,642,059May 5, 2020April 30, 2025NELSON, AMANDA Ereporter.nih.gov
ROS scavenging nanoparticles for mitigating oxidative stress in osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,641,378February 23, 2023January 31, 2029SHARMA, BLANKAreporter.nih.gov
Modulation of Inflammation in Osteoarthritis via CD14-mediated pattern recognitionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,640,656August 1, 2020July 31, 2026SCANZELLO, CARLA ROSEreporter.nih.gov
Elucidating the Mechanisms of Arthritic Flare and Developing TreatmentsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,629,617August 15, 2009July 31, 2027SCHWARZ, EDWARD M.reporter.nih.gov
Oxidative Stress and the Development of OsteoarthritisNIHNational Institute on Aging2021 to 2025$1,625,347September 30, 2012February 29, 2028LOESER, RICHARD Freporter.nih.gov
Advanced 7 Tesla imaging of the knee for root cause of OsteoarthritisNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,623,129August 1, 2023July 31, 2027ELLERMANN, JUTTA Mreporter.nih.gov
Development of Injectable Super-Lubricious Microgels for Sustained Release of Platelet-Rich Plasma to Treat Post-Traumatic OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,619,642May 10, 2023March 31, 2028ZUSTIAK, SILVIYA PETROVAreporter.nih.gov
Understanding A Molecular Cascade That Drives Neutrophil Mediated Pathology In ArthritisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,618,172February 9, 2023January 31, 2028ARANDJELOVIC, SANJAreporter.nih.gov
Deconstructing the molecular and cellular mechanisms of psoriatic arthritis pain by an improved animal modelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,617,503September 1, 2025August 31, 2028CHEN, YONGreporter.nih.gov
Home-Based Leg Dexterity Trainer for Management of Knee OsteoarthritisNIHNational Institute on Aging2024 to 2025$1,614,347September 25, 2024May 31, 2027VALERO, ERIKAreporter.nih.gov
Patient-centered Development of a Composite Digital Endpoint of Mobility and Pain for Knee OsteoarthritisNIHNational Institute of Neurological Disorders and Stroke2025$1,614,289August 1, 2025July 31, 2027KUMAR, DEEPAKreporter.nih.gov
Training Program in Adult and Pediatric RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,609,927May 1, 2005June 30, 2026LEWIS, DAVID BRAMreporter.nih.gov
Central Sensitization and Sleep Disturbance as Predictors of Treatment Outcomes in Patients with Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,605,759August 1, 2021July 31, 2026CAMPBELL, CLAUDIA MICHELLEreporter.nih.gov
DYNAMICS AND TUNING OF THE MHC II PRESENTED PEPTIDOMENIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,603,685September 19, 2018August 31, 2025SANTAMBROGIO, LAURAreporter.nih.gov
Ultrashort Echo Time Magnetic Resonance Imaging of Hemophilic ArthropathyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,584,359April 6, 2021March 2, 2024JANG, HYUNGSEOKreporter.nih.gov
Gene-environment interaction pathways in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,581,271April 9, 2019February 28, 2025HOLOSHITZ, JOSEPHreporter.nih.gov
Role of Glucose metabolism in Chondrocyte MechanotransductionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,576,819June 1, 2019February 28, 2026JUNE, RONALD KENTreporter.nih.gov
Regenerative Rehabilitative Principles in Modulating Weight Bearing and Joint Kinematics to Delay Post-Traumatic Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,576,611April 1, 2022January 31, 2027TSAI, LIANG-CHINGreporter.nih.gov
Population-Based Outcomes Research for Rheumatoid Arthritis: Rural Health DisparitiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,574,497September 24, 2024July 31, 2029CROWSON, CYNTHIA Sreporter.nih.gov
Molecular Genetics of Lyme ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,567,371January 15, 2020November 30, 2025WEIS, JANIS J.reporter.nih.gov
Epigenetic Regulation of Bone Regeneration in Inflammatory DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,566,325July 8, 2019June 30, 2025SHEN, JIEreporter.nih.gov
Rheumatic Diseases Research Training GrantNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,564,962May 15, 2013April 30, 2029GUMA, MONICAreporter.nih.gov
Heme and Nonheme Transition Metal Complexes, Reactivity, and MechanismNIHNational Institute of General Medical Sciences2023 to 2025$1,563,157September 1, 2023August 31, 2028GOLDBERG, DAVID Preporter.nih.gov
Targeting PHLPP to treat interval disc degeneration using surgical and drug delivery methodsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,562,670May 10, 2022April 30, 2027ILLIEN-JUNGER, SVENJAreporter.nih.gov
Metabolic Biomarkers for FibromyalgiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,561,793September 1, 2020August 31, 2025SLUKA, KATHLEEN Areporter.nih.gov
Morphologic and Kinematic Adaptations of the Subtalar Joint after Ankle Fusion Surgery in Patients with Varus-type Ankle OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,557,053September 12, 2023August 31, 2028ANDERSON, ANDREW EDWARDreporter.nih.gov
Cytokine Balance in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,542,904September 10, 2004January 31, 2027IVASHKIV, LIONEL Breporter.nih.gov
Synovial lymphatics and osteoarthritis in agingNIHNational Institute on Aging2021 to 2024$1,542,007January 1, 2020November 30, 2025XING, LIANPINGreporter.nih.gov
EMRSHN: Exploring the modulatory role of sex hormones along the neuromechanical axis in femalesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,540,067September 1, 2016April 30, 2024DHAHER, YASIN YOUSEFreporter.nih.gov
Immunological, serologic, and imaging biomarker predictors of flare in pediatric spondyloarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,535,030September 20, 2021February 28, 2027WEISS, PAMELA FITCHreporter.nih.gov
Role of protein citrullination in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,526,019February 1, 2020December 31, 2024MUSTELIN, TOMAS Mreporter.nih.gov
Research Training in RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,525,211September 1, 1986August 31, 2027KUHN, KRISTINE A.reporter.nih.gov
Disease Modifying Analgesia with CA8 Gene TherapyNIHNational Institute of Neurological Disorders and Stroke2021$1,516,241September 30, 2021September 15, 2023LEVITT, ROY C.reporter.nih.gov
The Role of the Nociceptor Endocytosis in Inflammatory PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,513,948June 15, 2022May 31, 2027BHATTACHARJEE, ARINDAMreporter.nih.gov
Develop BCL-xL proteolysis targeting chimeras as safer and better senolyticsNIHNational Institute on Aging2021 to 2023$1,510,674August 1, 2019March 31, 2025ZHENG, GUANGRONGreporter.nih.gov
Pathogenesis of Alphavirus induced Chronic Arthritis and MyositisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,508,138June 11, 2024April 30, 2029LENSCHOW, DEBORAH Jreporter.nih.gov
Decipher and target GABA metabolism and GABA receptor-mediated signaling in autoimmune diseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,499,167February 10, 2023January 31, 2028WANG, RUONINGreporter.nih.gov
Role of Desumoylase SENP6 in Joint Aging and Osteoarthritis DevelopmentNIHNational Institute on Aging2021 to 2023$1,495,470July 15, 2019September 30, 2025YANG, TAOreporter.nih.gov
Trained innate immunity and periodontitis-associated comorbiditiesNIHNational Institute of Dental & Craniofacial Research2022 to 2025$1,487,525February 1, 2022January 31, 2027HAJISHENGALLIS, GEORGIOSreporter.nih.gov
Growth hormone regulating chondrocyte metabolism for osteoarthritis developmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,486,776July 3, 2023May 31, 2028ZHU, SHOUANreporter.nih.gov
Translational Basic and Clinical Research Training in RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,479,519May 1, 2017May 31, 2027BUYON, JILL Preporter.nih.gov
Unraveling Fundamental Mechanisms of Interorgan Crosstalk in OsteoarthritisNIHNational Institute on Aging2024$1,476,001September 15, 2024August 31, 2027COLLINS, KELSEY HELEN-MARIEreporter.nih.gov
Design and Validation of Easy-to-Adopt Mass Spectrometry Assays of Importance to ObesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,473,524September 20, 2019January 31, 2025VAN EYK, JENNIFER Ereporter.nih.gov
Deep Learning-based Imaging Biomarkers for Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,471,178July 2, 2019October 31, 2024DENIZ, CEM MURATreporter.nih.gov
Activation of endogenous progenitors via a nanoparticle-conjugated fibrous system to enhance meniscus repairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,467,367February 20, 2023November 30, 2027QIN, LINGreporter.nih.gov
Imaging and therapeutic targeting of tissue crosstalk in the injured kneeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,454,755March 15, 2024February 28, 2029RUIZ GARZON, MARIA AMPAROreporter.nih.gov
Synthetic Cartilage-Capped, Regenerative Osteochondral Plugs to Heal Osteochondral DefectsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,449,070January 1, 2024December 31, 2025GRUNLAN, MELISSAreporter.nih.gov
Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2NIHNational Institute of General Medical Sciences2021 to 2023$1,448,376May 1, 2020January 31, 2025HANDEL, TRACY Mreporter.nih.gov
Profiling the human gut microbiome for potential analgesic bacterial therapiesNIHNational Institute of Neurological Disorders and Stroke2021$1,446,416September 24, 2021May 31, 2023STRANDWITZ, PHILIP PETERreporter.nih.gov
Cannabis Use Impact on Pain and Recovery Post-Surgery - The Role of the Endocannabinoid SystemNIHNational Institute of Neurological Disorders and Stroke2025$1,443,561September 5, 2025August 31, 2030INGRAM, SUSAN Lreporter.nih.gov
Integrative Predictors of Temporomandibular Degenerative Joint DiseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,439,575September 10, 2013January 30, 2026CEVIDANES, LUCIA Hreporter.nih.gov
HSS Research Institute Rheumatology TrainingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,438,910May 1, 2017April 30, 2027SALMON, JANE Ereporter.nih.gov
Early Detection and Monitoring of Osteonecrosis of the Femoral HeadNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,436,590March 1, 2023January 31, 2028JOHNSON, CASEY PETERreporter.nih.gov
The Role of Sodium Channel Nav1.7 in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,434,901March 18, 2024August 31, 2028LIU, CHUANJUreporter.nih.gov
Interdisciplinary Training in Rheumatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,431,535May 1, 2010May 31, 2026MAJOR, AMY Sreporter.nih.gov
Complement in the Pathogenesis of Autoimmune ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,418,939September 10, 2004November 30, 2025HOLERS, VERNON MICHAELreporter.nih.gov
Adding Bright Light Treatment to Cognitive-Behavioral Therapy for Insomnia to Prevent Chronic Post-Surgical Pain in Older AdultsNIHNational Institute on Aging2024 to 2025$1,415,293August 1, 2024July 31, 2029SMITH, MICHAEL Treporter.nih.gov
Expanded fibroblast subset drives pathology in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,413,588February 1, 2015August 31, 2026BRENNER, MICHAEL B.reporter.nih.gov
Bridging the gap between GWAS and mechanism in arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,412,097December 1, 2018March 31, 2030NIGROVIC, PETER Areporter.nih.gov
Molecular mechanisms of TAK1 regulation in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,407,925August 12, 2025July 31, 2028AHMED, SALAH-UDDINreporter.nih.gov
Neuroimaging Measures of Psychosocial Stress as Predictors of Articular and Arterial Inflammation, Cardiometabolic Disease, and Treatment Response in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,396,744September 27, 2021August 31, 2027BATHON, JOAN MARIEreporter.nih.gov
Inflammation and Cardiovascular Disease in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,381,165May 1, 2004May 31, 2024BATHON, JOAN MARIEreporter.nih.gov
Role of T-bet B cells in rheumatoid arthritisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,373,874December 12, 2023October 31, 2028ANOLIK, JENNIFER HOWITTreporter.nih.gov
Borrelia burgdorferi mitogen in development of arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,372,498April 1, 1993December 31, 2025WEIS, JANIS J.reporter.nih.gov
Development of Sodium Fluoride PET-MRI for Quantitative Assessment of Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,369,656August 16, 2019June 30, 2025GOLD, GARRY Ereporter.nih.gov
Defining the unique capacity of the miniature joint model for investigating the role of adipose tissue and its impacts on osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,365,070May 15, 2024April 30, 2029LIN, HANGreporter.nih.gov
Metabolomic Profiling to Identify Candidate Biomarker Profiles and Molecular Endotypes for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,362,647August 10, 2023July 31, 2028JUNE, RONALD KENTreporter.nih.gov
Factor VIIa-released extracellular vesicles: Their role in hemostasis and beyondNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,357,616March 15, 2024February 29, 2028LELLA, VIJAYA MOHAN RAOreporter.nih.gov
Interpretation and Utility of Novel Composite Structural Endpoints of Cumulative Damage and Disease Activity in Knee OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,355,310June 1, 2021June 30, 2023DRIBAN, JEFFREY Breporter.nih.gov
Targeting the PTH1R Signaling Pathway for Osteoarthritis Therapy by a Novel Disruptor PeptideNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,348,776August 1, 2020July 31, 2025WANG, BINreporter.nih.gov
Preclinical assessment of a novel systemic drug candidate for osteoarthritic painNIHNational Institute of Neurological Disorders and Stroke2023$1,348,453June 1, 2023May 31, 2025EVSEENKO, DENISreporter.nih.gov
Chondrocyte DNA Double-Strand Breaks in the Pathogenesis of OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,331,484May 7, 2020April 30, 2025JONASON, JENNIFER HARRELLreporter.nih.gov
Clinical Interpretation of PROMs in Care of Knee Osteoarthritis and TJRNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,331,338July 16, 2024April 30, 2028FRANKLIN, PATRICIA Dreporter.nih.gov
Biomechanics of Cartilage: Roles of Decorin in ECM Assembly and DegradationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,326,261August 1, 2019December 31, 2025HAN, LINreporter.nih.gov
Engineering Polymers to Scavenge DAMPs in Arthritis and LupusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,303,670August 15, 2018July 31, 2024SULLENGER, BRUCE ALANreporter.nih.gov
Characterizing the negative signaling in dendritic cells and macrophages to attenuate inflammation and bone destruction in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,290,781February 15, 2020December 31, 2025LI, YI-PINGreporter.nih.gov
Cellular Senescence Network: New Imaging Tools for Arthritis ImagingNIHNational Cancer Institute2023 to 2024$1,289,471September 23, 2021August 31, 2025DALDRUP-LINK, HEIKE ELIZABETHreporter.nih.gov
Epigenetic Mechanisms That Drive Genetic Risk in Juvenile ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$1,284,216September 26, 2022February 24, 2024JARVIS, JAMES Nreporter.nih.gov
Mechanism of Tgfbr2 in ChondroprotectionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,283,931April 1, 2013March 31, 2026SERRA, ROSA A.reporter.nih.gov
Lipid Metabolism in Articular Cartilage and OA PathogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,283,775June 12, 2024May 31, 2029SHEN, JIEreporter.nih.gov
Novel injectable analgesic delivery system for musculoskeletal pain managementNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,280,693August 1, 2019June 30, 2025NAIR, LAKSHMI Sreporter.nih.gov
Epigenetic Mechanisms That Drive Genetic Risk in Juvenile ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,278,332September 26, 2022August 31, 2027JARVIS, JAMES Nreporter.nih.gov
How Partial Meniscectomy Affects Contact Mechanics and Tissue ResponseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,275,050August 12, 2019April 30, 2025MAHER, SUZANNE A.reporter.nih.gov
The roles and mechanisms of inflammation resolution in the development of Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,268,125September 1, 2023August 31, 2028NORRIS, JILL Mreporter.nih.gov
Beyond Heart Disease in Rheumatoid Arthritis: MultimorbidityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,267,216September 1, 2000September 21, 2023CROWSON, CYNTHIA Sreporter.nih.gov
Molecular mechanisms governing chikungunya virus binding, tropism, and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,262,565July 3, 2024May 31, 2029SILVA, LAURIE A.reporter.nih.gov
Mechanotransduction in Meniscus Health and RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,257,415January 15, 2019December 31, 2024MCNULTY, AMY Lreporter.nih.gov
Cbf mediates articular cartilage regeneration and repair in agingNIHNational Institute on Aging2021 to 2023$1,250,727August 1, 2019April 30, 2026CHEN, WEIreporter.nih.gov
Role of CCR2 in osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,245,594August 1, 2017May 31, 2029LONGOBARDI, LARAreporter.nih.gov
Bioactive Injectable Cell Scaffold for Meniscus Injury Repair in a Large Animal ModelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,244,807September 4, 2023August 31, 2028JAYASURIYA, CHATHURAKA TEEKSHANAreporter.nih.gov
The Pregnancy Transcriptome in Rheumatoid Arthritis - RenewalNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,238,738September 20, 2017August 31, 2030JAWAHEER, DAMINIreporter.nih.gov
Ly6 family members in neutrophil biologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,228,273July 8, 2014June 30, 2026NIGROVIC, PETER Areporter.nih.gov
Development of Kv1.3 Monoclonal Antibodies Targeting TEM Cells for Treating Autoimmune DisordersNIHNational Institute of General Medical Sciences2021 to 2022$1,223,786September 5, 2014September 30, 2024RUCKER, JOSEPH BENJAMINreporter.nih.gov
Identifying Novel Biological Pathways for Gout using DNA Methylation and GeneticsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,218,051September 21, 2018November 30, 2023TIN, ADRIENNEreporter.nih.gov
Brain Mechanisms of Chronic Low-Back Pain: Specificity and Effects of Aging and SexNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,214,654April 1, 2023March 31, 2028GEHA, PAULreporter.nih.gov
WNT signaling in chondrocyte biology and osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,208,493September 1, 2024August 31, 2029WU, CHIA-LUNGreporter.nih.gov
GP130/STAT3 signalling in articular cartilage development and regenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,208,109April 1, 2018January 31, 2024EVSEENKO, DENISreporter.nih.gov
Epigenetic Regulation in Cartilage TissueNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,207,511March 1, 2016March 31, 2029O'KEEFE, REGIS Jreporter.nih.gov
Robotic System for Spinal Decompression and Interbody FusionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$1,207,172April 18, 2022March 31, 2026ARMAND, MEHRANreporter.nih.gov
Determining the impact of stromal cell-mediated type I IFN signaling on alphavirus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,206,704June 13, 2024April 30, 2029LENSCHOW, DEBORAH Jreporter.nih.gov
Uncovering the Genetic Mechanisms Behind Joint-Specific OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,202,184April 1, 2018January 31, 2024CAPELLINI, TERENCE Dreporter.nih.gov
Unicondylar Resurfacing in an Ovine Osteoarthritis Disease ModelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$1,199,996September 8, 2015July 31, 2025ESTES, BRADLEY Treporter.nih.gov
Regulation of inflammation by the ubiquitin proteasome pathwayNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,195,694February 1, 2024December 31, 2028BECK, DAVIDreporter.nih.gov
Roles of Type III Collagen in the Matrix Assembly and Mechanobiology of CartilageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,194,196May 10, 2024April 30, 2029HAN, LINreporter.nih.gov
The adaptive response of skeletal muscle, bone, and cartilage to severe knee trauma involving ACL disruption with and without concomitant injury to the meniscusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,193,778July 1, 2020June 30, 2025BEYNNON, BRUCEreporter.nih.gov
Uncovering the role of Setbp1 in fibroblast-like synoviocytes during inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,188,998September 6, 2017July 31, 2029BHATTARAM, PALLAVIreporter.nih.gov
Modulating PTOA development with parathyroid hormoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,187,907September 15, 2023August 31, 2028VAN DER MEULEN, MARJOLEIN Creporter.nih.gov
Systemic Inflammation in Microphysiological Models of Muscle and Vascular DiseaseNIHNational Center for Advancing Translational Sciences2021$1,186,828August 1, 2017June 30, 2022TRUSKEY, GEORGE Areporter.nih.gov
Individual cell bioprinting to generate multi-tissue type condensations for osteochondral tissue regenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,186,717April 5, 2023February 29, 2028ALSBERG, EBENreporter.nih.gov
Depositing Data Generated from Drug Test on microJoint Model into the Microphysiology Systems DatabaseNIHNational Center for Advancing Translational Sciences2021$1,186,687August 20, 2017June 30, 2023LIN, HANGreporter.nih.gov
NEURAXIAL AAVS TARGETING DRG CHANNELS INVOLVED IN CHRONIC POST INFLAMMATORY PAINNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,182,994January 1, 2024December 31, 2028YAKSH, TONY L.reporter.nih.gov
Roles of the Src-Family Kinases LynA and LynB in Macrophage Inflammatory SignalingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,175,786September 1, 2018August 31, 2025FREEDMAN, TANYA S.reporter.nih.gov
Longitudinal Biomechanics and Patient-Reported Outcomes after Periacetabular Osteotomy for Developmental Dysplasia of the HipNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,172,323February 10, 2023December 31, 2025HARRIS, MICHAEL Dreporter.nih.gov
Targeting hexokinase-2 in rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,170,750August 15, 2018May 31, 2024GUMA, MONICAreporter.nih.gov
Contribution of the NOD/RIPK2 signaling pathway to osteoarthritis susceptibilityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,169,691April 1, 2024March 31, 2029JURYNEC, MICHAEL Jreporter.nih.gov
Microphysiological joint-on-chip platform for the study of arthritic diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,162,683August 15, 2024July 31, 2029NEU, COREY Preporter.nih.gov
Mapping temporomandibular joint (TMJ) degeneration and painNIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,161,054July 1, 2024April 30, 2029CHEN, JIANFUreporter.nih.gov
Prevention of PTOA via regulation of the cytomechanics of chondrocytesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,160,687September 1, 2020July 31, 2026LU, X. LUCASreporter.nih.gov
A Novel Glycosaminoglycan Mimetic Scaffold for Cartilage RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,152,862March 16, 2021February 28, 2027ARINZEH, TREENA LYNNEreporter.nih.gov
Roles of SOX8 and SOX9 in Adult Articular CartilageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,149,371July 8, 2018June 30, 2024LEFEBVRE, VERONIQUE Mreporter.nih.gov
Mitochondrial Malfunction in T Cell Aging and Tissue InflammationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,144,649March 1, 2024February 28, 2029WEYAND, CORNELIA M.reporter.nih.gov
Disc-Facet Crosstalk During Spinal Degeneration and RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,143,510September 26, 2024August 31, 2029GULLBRAND, SARAH Ereporter.nih.gov
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RANIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,136,015August 1, 2019July 31, 2024BRENNER, MICHAEL B.reporter.nih.gov
Sex Dimorphism in Age-Related Knee OsteoarthritisNIHNational Institute on Aging2024 to 2025$1,132,326September 15, 2024May 31, 2028AMBROSIO, FABRISIAreporter.nih.gov
OA Pathogenesis beyond Cartilage: A preclinical study of the sources of OA painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,130,706March 1, 2018February 29, 2024ALLEN, KYLE Dreporter.nih.gov
Pathogenesis of autoimmune valvular carditisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,129,857July 15, 2014September 30, 2024BINSTADT, BRYCEreporter.nih.gov
The role of vascular failure and biomechanical stress in the development, progression and healing of osteochondritis dissecans lesionsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,129,716August 9, 2024May 31, 2029TOTH, FERENCreporter.nih.gov
Multidisciplinary Rheumatology Training ProgramNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,127,955July 1, 2003June 30, 2029BINGHAM, CLIFTON Oreporter.nih.gov
Objective tests utilizing Vibrational Spectroscopy for Diagnosis and Severity of Fibromyalgia and Related Pain SyndromesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,127,024September 15, 2020March 31, 2027HACKSHAW, KEVIN VICTORreporter.nih.gov
Carrier Free siRNA Conjugates as Disease Modifying Osteoarthritis DrugsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,122,583September 10, 2024July 31, 2029DUVALL, CRAIG LEWISreporter.nih.gov
Negative Regulation of OsteoclastogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,122,005August 1, 2024July 31, 2029IVASHKIV, LIONEL Breporter.nih.gov
Understanding the structural dynamics of TNF receptorsNIHNational Institute of General Medical Sciences2021 to 2023$1,120,569June 1, 2019May 31, 2024SACHS, JONATHAN Nreporter.nih.gov
Microbiota Control Lung Th17 Cell Response and Plasticity Leading to Autoimmune Lung DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,115,457August 1, 2020July 31, 2025WU, HSIN-JUNG JOYCEreporter.nih.gov
Disease Modifying Analgesia with CA8 Gene TherapyNIHNational Institute of Neurological Disorders and Stroke2023$1,109,446September 16, 2023September 30, 2026LEVITT, ROY C.reporter.nih.gov
Magnesium and Arthritis PathogenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,103,784January 15, 2019December 31, 2023GULKO, PERCIO Sreporter.nih.gov
Bacterial peptidylarginine deiminase, a link between gums and joint diseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,093,593February 1, 2013March 31, 2025POTEMPA, JAN Sreporter.nih.gov
Mechanism-rooted therapeutic strategies for immune-related toxicities induced by checkpoint inhibitorsNIHNational Cancer Institute2023 to 2025$1,093,197July 1, 2023June 30, 2028NURIEVA, ROZA INSAFETDINOVNAreporter.nih.gov
Treatment of Meniscal Problems in Osteoarthritis: TeMPONIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,093,180April 15, 2017March 31, 2023KATZ, JEFFREY NEILreporter.nih.gov
Comparing the Impact of Voluntary and Mandatory Bundled Payments on Disparities in Surgical CareNIHNational Institute on Minority Health and Health Disparities2021 to 2022$1,089,541June 19, 2019January 31, 2024NAVATHE, AMOL Sreporter.nih.gov
Characterizing and Restoring Joint Motion in Patients with Hallux RigidusNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,089,490September 1, 2020August 31, 2025LEDOUX, WILLIAM R.reporter.nih.gov
Genetics of Osteoarthritis Susceptibility, Heterogeneity and ProgressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,087,578August 22, 2024July 31, 2029MCDONALD DONNELLY, MERRY-LYNN NOELLEreporter.nih.gov
Repurposing FDA-approved drugs for the treatment of osteoarthritis using high-throughput screening in microphysiological modelsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,085,742August 15, 2024July 31, 2029LIN, HANGreporter.nih.gov
Regulation of cytosolic pattern recognition receptor signaling in macrophagesNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,085,226March 11, 2013March 1, 2024STEHLIK, CHRISTIANreporter.nih.gov
Environmental Factors Associated with the Development of OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,081,730February 1, 2024January 31, 2027DRIBAN, JEFFREY Breporter.nih.gov
The natural release of unusual peptidoglycan fragments drives persistent Lyme disease symptoms in susceptible hostsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,073,058June 15, 2023May 31, 2028JUTRAS, BRANDON LYONreporter.nih.gov
The Role of MicroRNA in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,069,484August 1, 2017October 31, 2024HUANG, JIANreporter.nih.gov
Cellular Senescence Network: New Imaging Tools for Arthritis ImagingNIHNational Cancer Institute2021 to 2022$1,059,697September 23, 2021August 31, 2023DALDRUP-LINK, HEIKE ELIZABETHreporter.nih.gov
Sleep, Pain, Active Social Life, and Inflammation (SPAI)NIHNational Heart, Lung, and Blood Institute2024 to 2025$1,056,093February 20, 2023January 31, 2027LEE, SOOMIreporter.nih.gov
INPP5E Signaling and Treatment in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,055,452July 18, 2024June 30, 2029YANG, SHUYINGreporter.nih.gov
Defining the host and pathogen determinants of peptidoglycan induced pathophysiology in Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,053,949August 1, 2024July 31, 2027JUTRAS, BRANDON LYONreporter.nih.gov
Role of PTPN2 in rheumatoid arthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,052,726June 1, 2019April 9, 2023BOTTINI, NUNZIOreporter.nih.gov
The immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,052,436September 1, 2012June 30, 2024LIU, CHUANJUreporter.nih.gov
Device Automation of an FDA-cleared CD-Microfluidic Platform for Rapid Tissue MicrosizingNIHNational Center for Advancing Translational Sciences2025$1,050,276September 25, 2025August 31, 2027ZOBI, AHMED NABILreporter.nih.gov
Weight loss, in vivo cartilage mechanics, and joint healthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,048,432January 15, 2019December 31, 2025DEFRATE, LOUIS E.reporter.nih.gov
15-LOX-1 as a druggable target in the acute to chronic pain transition of rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,041,920July 1, 2019May 31, 2025GREGUS, ANN MARIEreporter.nih.gov
Control of B cell differentiation by IFNg induced transcription factorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,039,868February 14, 2014November 30, 2025LUND, FRANCES E.reporter.nih.gov
CD8 T cell derived Granzyme K activates complement that drives synovial fibroblast inflammationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,028,392September 22, 2023August 31, 2028BRENNER, MICHAEL B.reporter.nih.gov
Viscoelastic Properties of Normal and OA ChondronsNIHNational Institute on Aging2021 to 2022$1,027,495January 1, 1998March 31, 2025GUILAK, FARSHIDreporter.nih.gov
Novel Non-Contrast MRI to Assess Synovitis in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,017,844April 19, 2024February 28, 2029KOGAN, FELIKSreporter.nih.gov
Title: BMP/TGFbeta crosstalk in cartilage maintenance and osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,015,872July 19, 2018April 30, 2024LYONS, KAREN M.reporter.nih.gov
Dissecting molecular mechanisms implicated in age- and osteoarthritis-related decline in anabolism in articular cartilageNIHNational Institute on Aging2021 to 2023$1,014,750February 1, 2019November 30, 2024EVSEENKO, DENISreporter.nih.gov
Efficacy of MeniscoFix for Sub-Total Meniscal Replacement: A Comprehensive Approach in Cadaver Knees and an Ovine Surgical ModelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,013,912July 15, 2022June 30, 2027WEADOCK, KEVIN Sreporter.nih.gov
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid ArthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,010,963September 13, 2018June 30, 2023BRENNER, MICHAEL B.reporter.nih.gov
Therapeutic targeting of GPCR Gbetagamma-GRK2 in osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$998,289February 21, 2019December 31, 2024KAMAL, FADIA ALIreporter.nih.gov
Piezo1 and Piezo2-dependent cartilage health and diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$996,072April 1, 2023March 31, 2028LEE, WHASILreporter.nih.gov
Understanding Interleukin-18 Mediated Susceptibility to Systemic HyperinflammationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$993,999April 1, 2021March 31, 2025CANNA, SCOTT WILLIAMreporter.nih.gov
T peripheral regulatory cells as modulators of T cell-B cell interactions in arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$991,974December 15, 2023November 30, 2028HENDERSON, LAUREN Areporter.nih.gov
Training Program in Rheumatic and Musculoskeletal Diseases ResearchNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$986,224May 1, 2016April 30, 2028MOUNTZ, JOHN Dreporter.nih.gov
Tfh cells: linking the gut microbiota to a gut-distal autoimmune diseaseNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$985,398August 1, 2013January 31, 2025WU, HSIN-JUNG JOYCEreporter.nih.gov
Local immunometabolism modulating biomaterials for immunosuppressive applicationsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$978,635May 14, 2021August 15, 2023ACHARYA, ABHINAVreporter.nih.gov
Pain-related Brain Mechanisms for Pain Catastrophizing Behavior in Response to Home-based Mindfulness-based Meditation Paired with Transcranial Direct Current StimulationNIHNational Institute of Nursing Research2022$973,809September 1, 2022January 31, 2025AHN, HYOCHOLreporter.nih.gov
Obesity, Biomechanics, and Inflammation in OsteoarthritisNIHNational Institute on Aging2021 to 2023$968,625September 30, 2013April 30, 2025GUILAK, FARSHIDreporter.nih.gov
Advancing Quality and Outcomes Measurement in RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$965,394February 15, 2019November 30, 2028YAZDANY, JINOOSreporter.nih.gov
Gene Regulation as a Foundation for Autoimmune Disease PreventionNIHNational Institute of Allergy and Infectious Diseases2021$963,738June 1, 2017May 31, 2023WEIRAUCH, MATTHEW TYSONreporter.nih.gov
Combination Therapy of Home-based Trans-cranial Direct Current Stimulation and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms in Older Adults with Knee OsteoarthritisNIHNational Institute of Nursing Research2023 to 2025$963,281April 14, 2020November 30, 2025AHN, HYOCHOLreporter.nih.gov
Targeted vaccines against pulmonary NTM infections in vulnerable populationsNIHNational Institute of Allergy and Infectious Diseases2025$950,092December 20, 2024November 30, 2029COLER, RHEA Nreporter.nih.gov
Obesity-Induced Inflammatory Mediators Predict Lack of Response in Patients with Rheumatoid Arthritis Starting Biological TherapiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$946,648September 1, 2024August 31, 2029GUMA, MONICAreporter.nih.gov
Defining the Role of Thymic Tolerance in the Pathogenesis of the COPA syndromeNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$946,280January 16, 2018December 31, 2023SHUM, ANTHONYreporter.nih.gov
Large-scale automatic analysis of the OAI magnetic resonance image datasetNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$929,619August 15, 2017April 30, 2024NIETHAMMER, MARCreporter.nih.gov
Molecular Engineering of Cartilage PCM Mechanotransduction in Osteoarthritis Using Biomimetic ProteoglycansNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$927,833July 10, 2022June 30, 2027MARCOLONGO, MICHELE Sreporter.nih.gov
Cincinnati Training Program in Pediatric RheumatologyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$920,093May 1, 2016April 30, 2030GROM, ALEXEI Areporter.nih.gov
DNA Repair and Mitochondrial Dysfunction in T Cell AgingNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$919,378December 20, 2013December 31, 2025WEYAND, CORNELIA M.reporter.nih.gov
Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic TrialNIHNational Center for Complementary & Integrative Health2023$911,699May 19, 2023August 31, 2024WANG, CHENCHENreporter.nih.gov
KLF4 in joint degradation and regenerationNIHNational Institute on Aging2021 to 2022$907,736September 30, 2018May 31, 2025LOTZ, MARTIN Kreporter.nih.gov
Restriction of psoriatic skin and joint disease by A20NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$907,333February 5, 2021November 30, 2025RAZANI, BAHRAMreporter.nih.gov
Therapeutic role of NFAT1 Transcription Factor in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$900,405August 1, 2024July 31, 2029WANG, JINXIreporter.nih.gov
Boston University Rheumatology Research Training (BURRT) T32 ProgramNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$894,646June 1, 2022May 31, 2027NEOGI, TUHINAreporter.nih.gov
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$887,284September 1, 2013February 29, 2024DU, JIANGreporter.nih.gov
Engineering synthetic ligands with potent allosteric inhibition of tumornecrosis factor receptorsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$878,581September 15, 2019June 30, 2024HACKEL, BENJAMINreporter.nih.gov
A simple and quantitative clinical assessment of neuromuscular recovery after ACL injuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$868,386September 12, 2019August 30, 2025VALERO, ERIKAreporter.nih.gov
Prognostic Study of the Risk Factors for Contralateral ACL InjuryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$861,401September 7, 2007August 31, 2025BEYNNON, BRUCEreporter.nih.gov
T resident memory cells in arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$851,419July 1, 2019May 31, 2025NIGROVIC, PETER Areporter.nih.gov
A Treatment Paradigm for Femoracetabular Impingement (FAI)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$849,426June 1, 2020May 31, 2023ESTES, BRADLEY Treporter.nih.gov
Tissue Engineering Approaches for Improved Treatment of Early Stage Osteonecrosis of the HipNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$844,366July 5, 2018April 30, 2024YANG, YUNZHIreporter.nih.gov
Human antibodies as broad alphavirus immunotherapeuticsNIHNational Institute of Allergy and Infectious Diseases2025$843,620June 6, 2025May 31, 2030LAI, JONATHAN R.reporter.nih.gov
The Exposome in Rheumatoid Arthritis and Systemic Lupus Erythematosus: EXACT Network PlanningNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$843,158August 18, 2025August 31, 2026NORRIS, JILL Mreporter.nih.gov
Systemic contribution of age-associated epigenetic mechanisms to osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$842,622September 9, 2019June 30, 2025YAU, MICHELLE SZU-HUEIreporter.nih.gov
Precision Monitoring of Treatment Response in Early Psoriatic Arthritis: Integrating at-Home RNA Microsampling into Ongoing, Remote, Smart Phone-Based, Digital Data CapturingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$838,694June 15, 2024May 31, 2028SCHER, JOSE U.reporter.nih.gov
Negative Regulation of OsteoclastogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2022$831,820September 8, 2008March 31, 2024IVASHKIV, LIONEL Breporter.nih.gov
Mechanisms of Oxytocins Analgesia in Older AdultsNIHNational Institute on Aging2021 to 2022$828,868August 1, 2018April 30, 2024CRUZ-ALMEIDA, YENISELreporter.nih.gov
Ultrashort Echo Time Magnetic Resonance Imaging of Hemophilic ArthropathyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$827,934June 1, 2024February 28, 2027JANG, HYUNGSEOKreporter.nih.gov
ACL Deficiency Modifies Topographical Degradation in Posttraumatic OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$824,998April 1, 2016March 31, 2025XIA, YANGreporter.nih.gov
Long-term Outcomes of Knee OA in the OAI CohortNIHNational Institute on Aging2021$819,214September 15, 2017May 31, 2024NEVITT, MICHAEL Creporter.nih.gov
MicroRNA-based therapy for rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$817,760July 12, 2018June 30, 2024AHMED, SALAH-UDDINreporter.nih.gov
Osteogenic Regulation of Vascular CalcificationNIHNational Heart, Lung, and Blood Institute2021 to 2022$810,000September 30, 2001November 30, 2024TOWLER, DWIGHT A.reporter.nih.gov
Regulation of Ubiquitination and ArthritisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$807,500May 5, 2018April 30, 2024MA, AVERIL Ireporter.nih.gov
Heart-Related Multiple Chronic Conditions in Primary Care: Behavioral TechnologyNIHNational Heart, Lung, and Blood Institute2021$799,451April 1, 2017March 31, 2023GUSTAFSON, DAVID Hreporter.nih.gov
Treatment and prevention of osteoarthritis with an intra-articular disease-modifying regenerative therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$797,793August 5, 2024July 31, 2026ANGLE, SIDDHESHreporter.nih.gov
Determining role of 14-3-3zeta in IL-17A signalingNIHNational Institute of Allergy and Infectious Diseases2025$795,696June 10, 2024April 30, 2030CHAKRAVARTI, RITUreporter.nih.gov
Remote Exposome Monitoring for Autoimmune DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$795,574September 18, 2023August 31, 2026LIAO, WILSONreporter.nih.gov
A Pilot Randomized Controlled Trial of Resilience Coaching for Adolescents with Chronic Musculoskeletal PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$794,396August 1, 2022June 30, 2027GMUCA, SABRINA ANDREAreporter.nih.gov
Type I interferon Impacts Treatment Response in Rheumatoid ArthritisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$790,560July 1, 2022June 30, 2027WAMPLER MUSKARDIN, THERESAreporter.nih.gov
Determining role of 14-3-3zeta in IL-17A signalingNIHNational Institute of Allergy and Infectious Diseases2024$790,019June 10, 2024February 13, 2025CHAKRAVARTI, RITUreporter.nih.gov
Engineered cells as agents of arthritis therapy governed by artificial signalingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$788,242September 17, 2024July 31, 2029BRUNGER, JONATHAN MATTHEWreporter.nih.gov
Alphavirus Pathogenesis and ImmunityNIHNational Institute of Allergy and Infectious Diseases2025$782,871April 2, 2025March 31, 2030MORRISON, THOMAS Ereporter.nih.gov
A Randomized, Double-Blind, Controlled, Multi-Center Trial of Colchicine in Calcium Pyrophosphate Deposition DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$777,869August 10, 2025July 31, 2030TEDESCHI, SARA K.reporter.nih.gov
Development and preliminary testing of a peer narrative video intervention for older adults with chronic painNIHNational Institute on Aging2025$777,114September 24, 2024August 31, 2027UEBELACKER, LISA Areporter.nih.gov
Temporal associations between systemic inflammation, cardiovascular risk profile and development of Alzheimer’s disease and related dementias in patients with rheumatoid arthritisNIHNational Institute on Aging2022 to 2025$760,568August 1, 2022April 30, 2027MYASOEDOVA, ELENAreporter.nih.gov
Risk Factors for End-Stage Glenohumeral OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$759,943September 18, 2024June 30, 2029ROWLANDS, ELIZABETH YANIKreporter.nih.gov
A novel regulating pathway in osteoclastogenesis and arthritic bone resorptionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$756,427April 1, 2018January 31, 2024PARK-MIN, KYUNG-HYUNreporter.nih.gov
Localization of Antibody Drugs to Arthritic Joints via Collagen HybridizationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$756,245August 22, 2024July 31, 2029YU, MICHAEL Sreporter.nih.gov
Mentoring Biomechanics Research in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$755,810April 1, 2018June 30, 2029SOUZA, RICHARD BRIANreporter.nih.gov
Biomechanics Contributions to Symptoms and Joint Health in Individuals with Rotator Cuff TearsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$753,068June 20, 2024April 30, 2028NICHOLS, JENNIFER A.reporter.nih.gov
Host-Microbiota Interactions in Crohn's Disease-associated SpondyloarthritisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$751,598April 2, 2018January 31, 2023LONGMAN, RANDY Sreporter.nih.gov
Defining stress REsilience And Mindfulness Effects in Rheumatoid Arthritis (DREAMER)NIHNational Center for Complementary & Integrative Health2022 to 2025$750,600January 1, 2022December 31, 2026PATTERSON, SARAH LYNNreporter.nih.gov
Integrating brain and behavioral measures of central pain inhibition to personalize treatment in chronic pain managementNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$748,927April 1, 2022February 28, 2027ALTER, BENEDICT Jreporter.nih.gov
The role of FGFR3 in the effects of PTH in the Mandibular CondyleNIHNational Institute of Dental & Craniofacial Research2021 to 2024$747,360April 1, 2020March 31, 2026DUTRA, ELIANEreporter.nih.gov
Development of Drug Delivery Technology for Stem Cell Based TMJ RegenerationNIHNational Institute of Dental & Craniofacial Research2021$742,838August 1, 2018January 31, 2024CHEN, MOreporter.nih.gov
Elucidating the neuroimmune mechanisms underlying pain and inflammation in autoimmune arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$742,426September 20, 2023June 30, 2028JAIN, AAKANKSHAreporter.nih.gov
Multidisciplinary Training in Molecular and Translational Rheumatology ResearchNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$741,678July 1, 2021June 30, 2026BATHON, JOAN MARIEreporter.nih.gov
Understanding the Role of Somatic Mutations in Adult Inflammatory DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$739,530January 1, 2022December 31, 2025BECK, DAVIDreporter.nih.gov
TMJ-on-a-chip for delineating multi-tissue crosstalk in inflammation and pathophysiological mechanical loadingsNIHNational Institute of Dental & Craniofacial Research2025$738,929August 1, 2025April 30, 2030LEE, CHANG HUNreporter.nih.gov
Using redox balance to guide surgical and therapeutic decisions for cartilage diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$736,331September 1, 2024August 31, 2028HENAK, CORINNE Rreporter.nih.gov
Immune cell contributions to inflammatory arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$735,460April 10, 2025March 31, 2030WARD, NICOLE LEANNEreporter.nih.gov
T cell expression of inflammatory chemokine receptorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$735,372May 15, 2025February 28, 2030RAO, DEEPAK ANGARAreporter.nih.gov
Association of the redesigned Comprehensive Care for Joint Replacement model with racial/ethnic and socioeconomic disparities in joint replacement surgeriesNIHNational Institute on Minority Health and Health Disparities2023 to 2024$734,538July 13, 2023January 31, 2027THIRUKUMARAN, CAROLINE PINTOreporter.nih.gov
Green Light Therapy and Brain Mechanisms of Pain and AnxietyNIHNational Center for Complementary & Integrative Health2025$733,870September 12, 2025May 31, 2030DA SILVA, JOYCE TEIXEIRAreporter.nih.gov
Resolving the interaction network of cell surface receptorsNIHNational Institute of General Medical Sciences2024 to 2025$733,091September 1, 2024August 31, 2029SMITH, ADAM W.reporter.nih.gov
Simulation framework to develop ankle exoskeleton gait assistance for older adultsNIHNational Institute on Aging2022 to 2024$727,327April 1, 2020March 31, 2026SONG, SEUNGMOONreporter.nih.gov
Mentoring in Patient Oriented Research in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$718,915August 25, 2022July 31, 2027NELSON, AMANDA Ereporter.nih.gov
Integrated Cartilage RepairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$716,032September 13, 2018June 30, 2025LU, HELEN Hreporter.nih.gov
The Role of Fat in OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$714,633August 1, 2023June 30, 2026COLLINS, KELSEY HELEN-MARIEreporter.nih.gov
Multivalent Nano-conjugates for Targeted Penetration of and Delivery to Dense Extracellular MatricesNIHNational Institute of Biomedical Imaging and Bioengineering2021$710,686September 15, 2018May 31, 2023HAMMOND, PAULA Treporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Brigham and Women's HospitalBoston, MA53$56.1 million0$0
Washington UniversitySaint Louis, MO40$43.8 million0$0
Massachusetts General HospitalBoston, MA22$42.3 million0$0
University of California, San FranciscoSan Francisco, CA34$42.2 million0$0
Johns Hopkins UniversityBaltimore, MD24$37.8 million0$0
University of Colorado DenverAurora, CO29$34.9 million0$0
University of FloridaGainesville, FL26$34.3 million0$0
New York University School of MedicineNew York, NY24$28.3 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA20$27.6 million0$0
University of Michigan at Ann ArborAnn Arbor, MI28$26.8 million0$0
University of PennsylvaniaPhiladelphia, PA26$26.5 million0$0
Stanford UniversityStanford, CA22$25.7 million0$0
Oklahoma Medical Research FoundationOklahoma City, OK7$24.7 million0$0
University of California, San DiegoLa Jolla, CA28$24.4 million0$0
Northwestern University at ChicagoChicago, IL17$24.3 million0$0
Rush University Medical CenterChicago, IL9$22.7 million0$0
Hospital for Special SurgeryNew York, NY16$22 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC32$21.5 million0$0
University of RochesterRochester, NY14$21.2 million0$0
Duke UniversityDurham, NC22$21 million0$0
University of Alabama at BirminghamBirmingham, AL13$15.7 million0$0
Mayo Clinic RochesterRochester, MN17$15.6 million0$0
University of UtahSalt Lake City, UT14$14.2 million0$0
Baylor College of MedicineHouston, TX5$13.6 million0$0
University of California at DavisDavis, CA9$12.9 million0$0
Columbia University Health SciencesNew York, NY13$12.8 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH11$12.8 million0$0
Brown UniversityProvidence, RI2$12.6 million0$0
Zetroz Systems, LLCTrumbull, CT3$12.2 million0$0
Vanderbilt University Medical CenterNashville, TN10$12.1 million0$0
University of MinnesotaMinneapolis, MN17$12 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR1$11.7 million0$0
Wake Forest UniversityWinston Salem, NC4$10.9 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA6$10.8 million0$0
Tufts University BostonBoston, MA6$10.4 million0$0
Rhode Island HospitalProvidence, RI10$10.2 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH10$9.5 million0$0
University of WashingtonSeattle, WA12$9.3 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA13$9.3 million0$0
Tufts Medical CenterBoston, MA6$9.2 million0$0
Benaroya Research Inst at Virginia MasonSeattle, WA5$9.1 million0$0
Scripps Research Institute, theLa Jolla, CA6$9 million0$0
Kai Research, INCRockville, MD2$8.3 million0$0
Boston Children's HospitalBoston, MA14$8.1 million0$0
University of Southern CaliforniaLos Angeles, CA10$7.9 million0$0
University of ArizonaTucson, AZ6$7.5 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA7$7.5 million0$0
University of Illinois at ChicagoChicago, IL6$7.4 million0$0
Beth Israel Deaconess Medical CenterBoston, MA4$7.3 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY4$7.2 million0$0
Trustees of Boston UniversityBoston, MA8$7 million0$0
University of Colorado at BoulderBoulder, CO4$6.6 million0$0
Vanderbilt UniversityNashville, TN7$6.5 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY1$6.3 million0$0
Feinstein Institute for Medical ResearchManhasset, NY4$6.2 million0$0
Yale UniversityNew Haven, CT6$6.1 million0$0
Harvard Medical SchoolBoston, MA5$5.4 million0$0
Rise Therapeutics, LLCRockville, MD2$5.4 million0$0
George Washington UniversityWashington, DC2$5.3 million0$0
North Carolina State UniversityRaleigh, NC2$5.3 million0$0
SUNY at BuffaloAmherst, NY5$5.1 million0$0
University of TX MD Anderson Can CTRHouston, TX4$4.7 million0$0
University of DelawareNewark, DE7$4.7 million0$0
George Mason UniversityFairfax, VA1$4.6 million0$0
Steadman Philippon Research InstituteVail, CO3$4.6 million0$0
University of Connecticut SCH of Med/dntFarmington, CT8$4.6 million0$0
University of MontanaMissoula, MT1$4.6 million0$0
Emory UniversityAtlanta, GA6$4.3 million0$0
Cytex Therapeutics Inc.Durham, NC4$4.2 million0$0
Dorian Therapeutics, Inc.San Carlos, CA1$4.2 million0$0
Thomas Jefferson UniversityPhiladelphia, PA4$4.1 million0$0
Wake Forest University Health SciencesWinston-Salem, NC3$4.1 million0$0
Helixbind, Inc.Boxborough, MA2$4 million0$0
University of ConnecticutStorrs, CT5$3.7 million0$0
Indiana University IndianapolisIndianapolis, IN4$3.5 million0$0
Northeastern UniversityBoston, MA5$3.4 million0$0
University of Miami School of MedicineCoral Gables, FL4$3.4 million0$0
Van Andel Research InstituteGrand Rapids, MI2$3.3 million0$0
Dartmouth CollegeHanover, NH1$3.2 million0$0
University of Maryland BaltimoreBaltimore, MD3$3.1 million0$0
Drexel UniversityPhiladelphia, PA3$3.1 million0$0
Virtici, LLCSeattle, WA1$3 million0$0
Montana State UniversityBozeman, MT2$2.9 million0$0
Tulane University of LouisianaNew Orleans, LA3$2.9 million0$0
Seattle Children's HospitalSeattle, WA2$2.8 million0$0
Ut Southwestern Medical CenterDallas, TX3$2.8 million0$0
University of HoustonHouston, TX1$2.8 million0$0
Eydis Bio, Inc.Durham, NC3$2.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY3$2.7 million0$0
University of Nebraska Medical CenterOmaha, NE4$2.6 million0$0
University of Vermont & ST Agric CollegeBurlington, VT3$2.6 million0$0
Medical College of WisconsinMilwaukee, WI3$2.6 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA4$2.6 million0$0
Columbia UniversityNew York, NY3$2.6 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA1$2.5 million0$0
Ohio UniversityAthens, OH3$2.5 million0$0
Chromatan CorporationDedham, MA1$2.5 million0$0
Spaulding Rehabilitation HospitalCharlestown, MA4$2.5 million0$0
Neuromuscular Dynamics, LLCLa Crescenta, CA2$2.5 million0$0
Regenosine INCPrinceton, NJ2$2.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025506$273,556,6820$0
2024507$242,447,3180$0
2023526$254,555,1510$0
2022526$251,786,0990$0
2021520$241,023,2720$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 7 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIHJanuary 7, 2028Not listedNotice number printed on 1 award here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.846November 23, 2026$375,000Same assistance listing 93.846 as 732 awards here
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0RFA-AR-26-006NIH93.846December 1, 2026Not listedSame assistance listing 93.846 as 732 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.846December 4, 2026Not listedSame assistance listing 93.846 as 732 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 732 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.846January 5, 2027Not listedSame assistance listing 93.846 as 732 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.846January 7, 2027Not listedSame assistance listing 93.846 as 732 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.846January 15, 2027$350,000Same assistance listing 93.846 as 732 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.846January 27, 2027$500,000Same assistance listing 93.846 as 732 awards here
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)PAR-25-141NIH93.846March 4, 2027Not listedSame assistance listing 93.846 as 732 awards here
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin DiseasesPAR-27-109NIH93.846March 4, 2027$600,000Same assistance listing 93.846 as 732 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 732 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.846April 5, 2027Not listedSame assistance listing 93.846 as 732 awards here
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)PA-24-201NIH93.846April 18, 2027Not listedSame assistance listing 93.846 as 732 awards here

Updated November 4, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-04). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.