Data / Research funding / Alzheimer's Disease Related Dementias (ADRD)
Alzheimer's Disease Related Dementias (ADRD): 2,080 NIH awards ($3.9B) to 303 organizations
2,080 NIH awards ($3.9B) in the NIH spending category Alzheimer's Disease Related Dementias (ADRD), to 303 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
The 500 largest of 2,080 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project | NIH | National Institute on Aging | 2022 to 2025 | $66,521,567 | September 1, 2022 | August 31, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| ADRC Consortium for Clarity in ADRD Research Through Imaging | NIH | National Institute on Aging | 2023 to 2024 | $60,357,563 | September 15, 2023 | August 31, 2028 | JOHNSON, STERLING C | reporter.nih.gov |
| ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2) | NIH | National Institute on Aging | 2021 to 2025 | $56,766,232 | September 15, 2019 | August 31, 2030 | BOEVE, BRADLEY F | reporter.nih.gov |
| Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium | NIH | National Institute on Aging | 2021 to 2025 | $37,497,984 | September 30, 2021 | August 31, 2026 | HOHMAN, TIMOTHY J | reporter.nih.gov |
| Cognitive training to reduce incidence of cognitive impairment in older adults | NIH | National Institute on Aging | 2021 to 2024 | $37,326,564 | February 1, 2021 | January 31, 2027 | O'BRIEN, JENNIFER LEE | reporter.nih.gov |
| The Progressive Supranuclear Palsy Clinical Trial Platform (PTP) | NIH | National Institute on Aging | 2024 to 2025 | $30,281,212 | August 15, 2024 | July 31, 2029 | BOXER, ADAM L. | reporter.nih.gov |
| A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Dementia with Lewy Bodies | NIH | National Institute on Aging | 2021 to 2023 | $29,498,064 | May 15, 2021 | April 30, 2025 | CAGGIANO, ANTHONY O | reporter.nih.gov |
| US POINTER Neuroimaging Ancillary Study | NIH | National Institute on Aging | 2021 to 2025 | $24,762,483 | August 1, 2019 | March 31, 2027 | LANDAU, SUSAN M | reporter.nih.gov |
| Center without Walls for Imaging Proteinopathies with PET | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $24,457,384 | September 24, 2019 | July 31, 2029 | MACH, ROBERT H | reporter.nih.gov |
| Metformin in Alzheimer's dementia Prevention (MAP) | NIH | National Institute on Aging | 2021 to 2025 | $24,224,790 | August 15, 2019 | April 30, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| Wisconsin Registry for Alzheimer's Prevention | NIH | National Institute on Aging | 2023 to 2025 | $21,491,270 | June 1, 2023 | February 29, 2028 | JOHNSON, STERLING C | reporter.nih.gov |
| Unraveling the earliest phases of vascular cognitive impairment and dementia using CADASIL--a monogenic form of small vessel cerebrovascular disease | NIH | National Institute on Aging | 2021 to 2025 | $21,188,740 | September 30, 2021 | August 31, 2027 | PAULSEN, JANE S | reporter.nih.gov |
| A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Mild-to-Moderate Dementia with Lewy Bodies (DLB) | NIH | National Institute on Aging | 2023 to 2025 | $21,072,036 | February 1, 2023 | January 31, 2026 | ALAM, JOHN | reporter.nih.gov |
| Frontotemporal Dementia: Genes, Images, and Emotions | NIH | National Institute on Aging | 2021 to 2025 | $20,694,825 | September 1, 2002 | April 30, 2028 | GORNO TEMPINI, MARIA LUISA | reporter.nih.gov |
| Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-Old | NIH | National Institute on Aging | 2022 to 2025 | $20,680,832 | September 15, 2017 | June 30, 2027 | WHITMER, RACHEL A | reporter.nih.gov |
| Mayo Alzheimer's Disease Research Center | NIH | National Institute on Aging | 2021 to 2025 | $18,486,241 | July 1, 2019 | April 30, 2029 | BOEVE, BRADLEY F | reporter.nih.gov |
| Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease | NIH | National Institute on Aging | 2022 to 2025 | $17,997,906 | May 15, 2022 | January 31, 2028 | GONZALEZ, HECTOR M | reporter.nih.gov |
| Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal) | NIH | National Institute on Aging | 2021 to 2025 | $17,112,209 | August 15, 2018 | May 31, 2029 | HUGHES, TIMOTHY M. | reporter.nih.gov |
| Offspring Study of Mechanisms for Racial Disparities in Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $17,095,138 | September 1, 2016 | May 31, 2027 | MANLY, JENNIFER JAIE | reporter.nih.gov |
| Biomarkers of Cognitive Decline Among Normal Individuals: The Biocard Cohort | NIH | National Institute on Aging | 2021 to 2025 | $16,952,609 | July 1, 2009 | May 31, 2027 | ALBERT, MARILYN S. | reporter.nih.gov |
| Diabetes and brain amyloid in middle aged Hispanics | NIH | National Institute on Aging | 2021 to 2025 | $16,383,484 | September 1, 2015 | May 31, 2027 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic Transitions | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $16,244,011 | September 24, 2001 | August 31, 2026 | JUDD, SUZANNE E | reporter.nih.gov |
| ARIC Neurocognitive Study (ARIC-NCS) Renewal | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $15,682,941 | July 7, 2010 | March 31, 2024 | CORESH, JOSEF | reporter.nih.gov |
| Alzheimer's Disease Research Centers | NIH | National Institute on Aging | 2021 to 2025 | $14,719,450 | September 1, 2020 | March 31, 2030 | CHUI, HELENA CHANG | reporter.nih.gov |
| Integrative Pathways to Cognitive, Affective, and Brain Health | NIH | National Institute on Aging | 2022 to 2025 | $14,488,542 | September 30, 2022 | August 31, 2028 | RYFF, CAROL D. | reporter.nih.gov |
| Mild Cognitive Impairment: A Prospective Community Study | NIH | National Institute on Aging | 2021 to 2025 | $14,337,476 | September 1, 2005 | April 30, 2026 | GANGULI, MARY | reporter.nih.gov |
| Study of Healthy Aging in African Americans | NIH | National Institute on Aging | 2023 to 2025 | $14,240,222 | January 1, 2017 | May 31, 2028 | WHITMER, RACHEL A | reporter.nih.gov |
| MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $14,117,524 | April 1, 2019 | September 30, 2026 | GUSTAFSON, DEBORAH R. | reporter.nih.gov |
| Vanderbilt Memory & Aging Project | NIH | National Institute on Aging | 2021 to 2025 | $14,019,775 | March 15, 2011 | March 31, 2027 | JEFFERSON, ANGELA L. | reporter.nih.gov |
| 1Florida Alzheimer's Disease Research Center | NIH | National Institute on Aging | 2021 to 2025 | $13,348,245 | June 15, 2020 | April 30, 2027 | SMITH, GLENN E. | reporter.nih.gov |
| Epidemiological and Genetic Investigations of Blood-Based Biomarkers for Alzheimer's Disease in the Multiethnic, Washington Heights, Inwood, Columbia Aging Project (WHICAP) | NIH | National Institute on Aging | 2021 to 2025 | $13,310,071 | June 1, 2021 | March 31, 2027 | MAYEUX, RICHARD P | reporter.nih.gov |
| ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028 | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $13,305,831 | July 7, 2010 | March 31, 2029 | CORESH, JOSEF | reporter.nih.gov |
| MIND DIET AND DEMENTIA PREVENTION IN ISCHEMIC STROKE PATIENTS | NIH | National Institute on Aging | 2021 to 2025 | $13,186,351 | September 1, 2020 | May 31, 2027 | AGGARWAL, NEELUM T. | reporter.nih.gov |
| Testing Hypothesized Pathways Linking Infection, Physical Activity, Apoe Genotype, And Biological Sex To Low Dementia Prevalence And Reduced Brain Atrophy In Two Native American Populations | NIH | National Institute on Aging | 2022 to 2025 | $12,690,286 | April 15, 2017 | April 30, 2027 | KAPLAN, HILLARD S | reporter.nih.gov |
| Investigating regional and cellular vulnerabilities to tau pathology in young-onset Alzheimer's disease | NIH | National Institute on Aging | 2022 to 2025 | $12,536,106 | February 15, 2022 | November 30, 2026 | MURRAY, MELISSA ERIN | reporter.nih.gov |
| Exploring Cognitive Aging Using Reference Ability Neural Networks | NIH | National Institute on Aging | 2021 to 2025 | $12,167,937 | September 1, 2011 | June 30, 2027 | STERN, YAAKOV | reporter.nih.gov |
| I3C DECADE: Developmental Epidemiology of Childhood Cardiovascular Exposures and Alzheimer’s Dementia | NIH | National Institute on Aging | 2022 to 2025 | $11,889,015 | July 1, 2022 | April 30, 2028 | MACLEHOSE, RICHARD F | reporter.nih.gov |
| Estrogens, Cardiometabolic Health, and Female Cognitive Aging | NIH | National Institute on Aging | 2022 to 2025 | $11,521,268 | March 1, 2022 | February 28, 2027 | DANIEL, JILL M | reporter.nih.gov |
| Sleep in Neurocognitive Aging and Alzheimers Research (SANAR) | NIH | National Institute on Aging | 2021 to 2025 | $11,494,462 | February 1, 2021 | January 31, 2027 | RAMOS, ALBERTO RAFAEL | reporter.nih.gov |
| Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population Study | NIH | National Institute on Aging | 2021 to 2025 | $11,418,675 | September 1, 2021 | May 31, 2027 | RAJAN, KUMAR B. | reporter.nih.gov |
| Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $11,402,108 | September 30, 2004 | May 31, 2027 | BARNES, LISA L | reporter.nih.gov |
| Complement Mediated Remodeling in Pulmonary Vascular Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $11,355,302 | August 1, 2020 | June 30, 2026 | STENMARK, KURT R. | reporter.nih.gov |
| Pre-Symptomatic Familial ALS (Pre-fALS) Study: From Prodrome and Biomarkers to ALS/FTD Prevention | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $11,282,768 | September 15, 2018 | July 31, 2029 | BENATAR, MICHAEL | reporter.nih.gov |
| Longitudinal Imaging Biomarkers of Prodromal DLB | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $10,821,041 | September 25, 2017 | August 31, 2027 | KANTARCI, KEJAL | reporter.nih.gov |
| VCID Biomarkers Coordinating Center | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $10,493,954 | September 30, 2016 | June 30, 2027 | GREENBERG, STEVEN M | reporter.nih.gov |
| Vermont Center for Cardiovascular and Brain Health | NIH | National Institute of General Medical Sciences | 2021 to 2024 | $10,185,844 | August 6, 2020 | May 31, 2026 | CUSHMAN, MARY | reporter.nih.gov |
| Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility | NIH | National Institute on Aging | 2021 to 2024 | $9,901,034 | May 1, 2021 | February 28, 2026 | REDLINE, SUSAN S. | reporter.nih.gov |
| Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid and Tau in Older Adults (IPAT-study) | NIH | National Institute on Aging | 2022 to 2025 | $9,488,371 | August 1, 2022 | July 31, 2027 | ZHANG, RONG | reporter.nih.gov |
| BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a Trial | NIH | National Institute on Aging | 2021 to 2025 | $9,481,336 | February 15, 2021 | November 30, 2026 | HANLEY, DANIEL F | reporter.nih.gov |
| Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSP | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $9,418,230 | September 1, 2021 | August 31, 2026 | GOATE, ALISON M | reporter.nih.gov |
| The San Antonio Heart and Mind Study | NIH | National Institute on Aging | 2023 to 2025 | $9,286,743 | July 1, 2023 | March 31, 2029 | SATIZABAL, CLAUDIA L | reporter.nih.gov |
| African Americans Fighting Alzheimer’s in Midlife (AA-FAIM) | NIH | National Institute on Aging | 2021 to 2025 | $9,250,399 | August 1, 2016 | November 30, 2027 | GLEASON, CAREY E | reporter.nih.gov |
| Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN Cohort | NIH | National Institute on Aging | 2021 to 2025 | $9,240,061 | August 1, 2017 | December 31, 2027 | YASSA, MICHAEL A | reporter.nih.gov |
| Identification of TDP-43 Modifiers Through Single-Cell Transcriptional and Epigenomic Dissection of ALS and FTLD-MND | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $9,106,321 | September 29, 2021 | August 31, 2026 | DONNELLY, CHRISTOPHER JAMES | reporter.nih.gov |
| Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions | NIH | National Institute on Aging | 2021 to 2025 | $8,654,669 | July 1, 2021 | June 30, 2027 | TEMPLE, SALLY | reporter.nih.gov |
| P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India | NIH | National Institute on Aging | 2024 to 2025 | $8,548,820 | September 15, 2024 | August 31, 2029 | NARAYAN, KABAYAM M VENKAT | reporter.nih.gov |
| ASYMMETRIC NEURODEGENERATION AND LANGUAGE IN PRIMARY PROGRESSIVE APHASIA | NIH | National Institute on Aging | 2022 to 2025 | $8,306,361 | June 15, 2022 | March 31, 2027 | MESULAM, MAREK-MARSEL M | reporter.nih.gov |
| The Physical Biology of Neurodegeneration in Sporadic Amyotrophic Lateral Sclerosis/Frontotemporal Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $8,227,499 | September 1, 2021 | August 31, 2027 | PHATNANI, HEMALI | reporter.nih.gov |
| Race / Ethncicity, Hypertension and Prevention of VCID and Stroke after Intracerebral Hemmorrhage | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $8,210,604 | February 1, 2016 | July 31, 2027 | ROSAND, JONATHAN | reporter.nih.gov |
| Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $8,189,971 | September 15, 2024 | August 31, 2026 | GITLER, AARON D. | reporter.nih.gov |
| THE NIH PRECISION BRAIN HEALTH NETWORK: Open and Inclusive Measurement of Neuropsychological Change for AD/ADRD Primary Prevention Trials | NIH | National Institute on Aging | 2025 | $7,948,867 | August 1, 2025 | July 31, 2030 | SLIWINSKI, MARTIN J | reporter.nih.gov |
| Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasia | NIH | National Institute on Aging | 2023 to 2025 | $7,878,167 | September 15, 2017 | August 31, 2028 | ROGALSKI, EMILY J | reporter.nih.gov |
| ERICH-GENE | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $7,768,356 | August 1, 2010 | June 30, 2025 | DEMEL, STACIE | reporter.nih.gov |
| The POINTER Neurovascular Ancillary Study | NIH | National Institute on Aging | 2021 to 2024 | $7,761,498 | April 15, 2020 | December 31, 2025 | BRINKLEY, TINA E | reporter.nih.gov |
| Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer's Disease and Related Dementias | NIH | National Institute on Aging | 2021 to 2025 | $7,757,977 | July 1, 2021 | June 30, 2027 | KAYED, RAKEZ | reporter.nih.gov |
| Vietnamese Insights into Cognitive Aging Program (VIP) | NIH | National Institute on Aging | 2021 to 2025 | $7,598,841 | February 15, 2021 | May 31, 2026 | MEYER, OANH L | reporter.nih.gov |
| Look AHEAD Sleep: Sleep-disordered breathing, circadian rest/activity rhythms, and the risk of Alzheimer's disease and related dementias in Look AHEAD | NIH | National Institute on Aging | 2021 to 2025 | $7,592,411 | August 15, 2021 | May 31, 2027 | UDEH-MOMOH, CHINEDU THERESA | reporter.nih.gov |
| REpeated ASseSsmEnt of SurvivorS in ICH (REASSESS ICH) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $7,516,765 | January 1, 2022 | December 31, 2027 | ZIAI, WENDY C | reporter.nih.gov |
| Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience | NIH | National Institute on Aging | 2021 to 2024 | $7,413,273 | September 15, 2020 | May 31, 2025 | SESHADRI, SUDHA | reporter.nih.gov |
| CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimers Disease | NIH | National Institute on Aging | 2021 to 2025 | $7,389,501 | January 15, 2021 | December 31, 2026 | RAO, STEPHEN MARK | reporter.nih.gov |
| Predictors of Altered CNS Structure, Function, and Connectomics in the Elderly using a Health Disparities Framework | NIH | National Institute on Aging | 2022 to 2025 | $7,350,257 | February 15, 2022 | November 30, 2027 | COHEN, ANN D. | reporter.nih.gov |
| Leveraging the 24-hour movement paradigm to preserve cognitive function and prevent Alzheimer's disease: The Multi-Ethnic Study of Atherosclerosis (MESA) 24H-ACT Study | NIH | National Institute on Aging | 2021 to 2024 | $7,263,372 | May 1, 2021 | April 30, 2026 | DIAZ, KEITH M | reporter.nih.gov |
| The VETSA Longitudinal MRI Twin Study of Aging (VETSA MRI 4) | NIH | National Institute on Aging | 2022 to 2025 | $7,252,240 | June 1, 2022 | March 31, 2027 | ELMAN, JEREMY A | reporter.nih.gov |
| A Pragmatic Trial of the UCSF Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $6,593,404 | September 15, 2022 | August 31, 2027 | POSSIN, KATHERINE LAUREL | reporter.nih.gov |
| Precision Editing of Granulin Mutations that Cause Frontotemporal Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $6,580,415 | August 15, 2025 | July 31, 2029 | SONTHEIMER, ERIK J. | reporter.nih.gov |
| Dementia with Lewy Bodies Consortium | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $6,563,373 | September 30, 2016 | August 31, 2027 | LEVERENZ, JAMES BRUCE | reporter.nih.gov |
| Extracranial Carotid Atherosclerosis Contributions to Cognitive Impairment and Alzheimer's Disease Risk | NIH | National Institute on Aging | 2021 to 2025 | $6,475,434 | August 15, 2021 | May 31, 2027 | WEINKAUF, CRAIG C | reporter.nih.gov |
| The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center study | NIH | National Institute on Aging | 2021 to 2024 | $6,442,962 | June 15, 2020 | March 31, 2025 | VERGHESE, JOE | reporter.nih.gov |
| Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman Primates | NIH | National Institute on Aging | 2025 | $6,424,607 | September 15, 2025 | September 14, 2029 | BAXTER, MARK G | reporter.nih.gov |
| Contributions of stress reactivity to risk of Alzheimer's disease and related dementia's in a community-based cohort | NIH | National Institute on Aging | 2021 to 2025 | $6,416,931 | September 30, 2021 | May 31, 2027 | KERSHAW, KIARRI N | reporter.nih.gov |
| Validation of the Remote Cognitive Aging and Alzheimer’s Disease REsearch (R-CARE) Toolbox for Diverse Populations | NIH | National Institute on Aging | 2023 to 2025 | $6,381,700 | August 15, 2023 | May 31, 2028 | LIPTON, RICHARD B. | reporter.nih.gov |
| Cerebral small vessel disease burden and racial disparity in vascular cognitive impairment and Alzheimer’s disease and its related dementias | NIH | National Institute on Aging | 2021 to 2025 | $6,336,090 | September 15, 2021 | May 31, 2027 | HYACINTH, HYACINTH IDU | reporter.nih.gov |
| A Life Course Approach to Integrating Trauma and Cognitive Aging: A Cohort of 9/11 Responders | NIH | National Institute on Aging | 2021 to 2024 | $6,329,240 | May 15, 2015 | April 30, 2026 | CLOUSTON, SEAN | reporter.nih.gov |
| Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project II | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $6,308,426 | August 15, 2024 | July 31, 2029 | ALOSCO, MICHAEL | reporter.nih.gov |
| Validation of Biomarkers of Small Vessel Injury in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,258,167 | September 29, 2021 | July 31, 2026 | ROSENBERG, GARY ALLEN | reporter.nih.gov |
| Washington University University of Texas Southwestern VCID Consortium Site | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,224,729 | September 29, 2021 | July 31, 2026 | LEE, JIN-MOO | reporter.nih.gov |
| Expanding insights into FTD disease mechanisms | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $6,199,699 | December 1, 2016 | November 30, 2024 | PETRUCELLI, LEONARD | reporter.nih.gov |
| IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia | NIH | National Institute on Aging | 2021 to 2023 | $6,168,197 | April 15, 2020 | March 31, 2024 | HAY, MEREDITH | reporter.nih.gov |
| The University of Kentucky MarkVCID Biomarker Validation Cohort: Development of a Toolbox to Advance VCID Interventional Studies | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,120,000 | September 29, 2021 | July 31, 2026 | JICHA, GREGORY A | reporter.nih.gov |
| MarkVCID Validation in the General Community | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $6,100,999 | September 23, 2021 | July 31, 2026 | PETERSEN, RONALD C | reporter.nih.gov |
| Biomarker Evaluation in Young Onset Dementia from Diverse Populations (BEYONDD) | NIH | National Institute on Aging | 2022 | $6,065,228 | September 15, 2022 | August 31, 2025 | BOXER, ADAM L. | reporter.nih.gov |
| VCID CWOW: Identifying Novel Targets to Treat Cerebral Amyloid Angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $5,949,022 | September 18, 2024 | August 31, 2027 | HOWELL, GARETH R | reporter.nih.gov |
| URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related Dementias | NIH | National Institute on Aging | 2021 to 2024 | $5,941,036 | September 1, 2019 | May 31, 2026 | NELSON, LONNIE A. | reporter.nih.gov |
| PNA5: A Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Vascular Dementia and Alzheimer's Disease Related Dementia: an FDA required Toxicology Study | NIH | National Institute on Aging | 2023 to 2025 | $5,906,221 | September 1, 2023 | August 31, 2027 | HAY, MEREDITH | reporter.nih.gov |
| Late-onset Unexplained Epilepsy as a Risk Factor for Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $5,883,988 | September 1, 2023 | February 28, 2029 | LAM, ALICE D | reporter.nih.gov |
| Examining Effects of Intensive BP Control on MCI/Dementia and Plasma Biomarker Trajectories by AD Pathology: Elucidating neuroprotective effects in the racially and ethnically diverse SPRINT trial | NIH | National Institute on Aging | 2025 | $5,789,766 | September 30, 2025 | June 30, 2030 | BRESS, ADAM P | reporter.nih.gov |
| VCID and Stroke in a Bi-racial National Cohort | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $5,761,773 | September 24, 2001 | September 16, 2024 | JUDD, SUZANNE E | reporter.nih.gov |
| Cerebral tau deposition and comorbid cerebrovascular disease across the Alzheimer's disease continuum in Mexican Americans | NIH | National Institute on Aging | 2024 to 2025 | $5,730,361 | August 15, 2024 | August 31, 2029 | HABES, MOHAMAD | reporter.nih.gov |
| Brain pathologies, reserve and cognition in aging and dementia | NIH | National Institute on Aging | 2022 to 2025 | $5,694,414 | March 1, 2009 | March 31, 2027 | TOMASZEWSKI-FARIAS, SARAH E | reporter.nih.gov |
| Roles of Gray Matter Brain Aging and Small Vessel Disease in AD Pathophysiology | NIH | National Institute on Aging | 2021 | $5,546,075 | March 1, 2005 | February 29, 2024 | AIZENSTEIN, HOWARD J | reporter.nih.gov |
| Phase II clinical trial of transcranial direct current stimulation in the treatment of primary progressive aphasia | NIH | National Institute on Aging | 2022 to 2025 | $5,516,416 | September 30, 2022 | May 31, 2027 | HAMILTON, ROY H | reporter.nih.gov |
| Primary Care Detection of Cognitive Impairment Leveraging Health and Consumer Technologies in Underserved Communities: The MyCog Trial | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $5,515,593 | September 25, 2017 | August 31, 2027 | WOLF, MICHAEL S | reporter.nih.gov |
| Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural Population | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $5,484,212 | March 6, 2020 | March 21, 2025 | GALVIN, JAMES E | reporter.nih.gov |
| An automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populations | NIH | National Institute on Aging | 2023 to 2025 | $5,455,529 | August 15, 2023 | June 30, 2028 | GORNO TEMPINI, MARIA LUISA | reporter.nih.gov |
| Vascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathology | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $5,423,836 | September 19, 2024 | August 31, 2027 | YANG, ANDREW CHRIS | reporter.nih.gov |
| Investigating the Benefits of Remotely-supervised Neuromodulation in Primary Progressive Aphasia | NIH | National Institute on Aging | 2025 | $5,343,452 | September 15, 2025 | August 31, 2029 | HENRY, MAYA | reporter.nih.gov |
| Clinical Features and Neuropathological Basis of Sleep Wake Behavior in Alzheimer's and PSP | NIH | National Institute on Aging | 2021 to 2025 | $5,284,458 | June 1, 2019 | March 31, 2029 | NEYLAN, THOMAS C | reporter.nih.gov |
| Digital Health Technologies for Monitoring Motor Function in Progressive Supranuclear Palsy and Dementia with Lewy Bodies | NIH | National Institute on Aging | 2025 | $5,174,076 | September 1, 2025 | August 31, 2029 | VAZIRI, ASHKAN | reporter.nih.gov |
| Environmental Exposures and Brain Health | NIH | National Institute on Aging | 2025 | $5,164,012 | September 1, 2025 | August 31, 2029 | JAMES, PETER | reporter.nih.gov |
| Microbial Impact on NeuroDegeneration in Alzheimer's Dementia: MIND-AD | NIH | National Institute on Aging | 2021 to 2025 | $5,121,493 | September 30, 2021 | May 31, 2027 | SPIRA, ADAM PETER | reporter.nih.gov |
| Targeting Dysregulated RNA Splicing in Neurodegenerative Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $5,093,143 | September 1, 2023 | August 31, 2028 | LAGIER-TOURENNE, CLOTILDE | reporter.nih.gov |
| A Precision Medicine Approach for the Study of Targetable Pathways in Vascular Dementia | NIH | National Institute on Aging | 2022 to 2025 | $5,086,657 | February 1, 2022 | November 30, 2026 | GOATE, ALISON M | reporter.nih.gov |
| Study of Latinos Investigation of Neurocognitive Aging 2 | NIH | National Institute on Aging | 2021 | $5,055,467 | September 1, 2015 | April 30, 2023 | GONZALEZ, HECTOR M | reporter.nih.gov |
| Brain Health and Ethnic Disparities in ADRD Risk: The Case of Arab Americans | NIH | National Institute on Aging | 2021 to 2025 | $5,040,162 | April 1, 2021 | March 31, 2027 | ANTONUCCI, TONI CLAUDETTE | reporter.nih.gov |
| Multi-scale and multi-modality imaging of neuropathology in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,964,481 | September 22, 2023 | August 31, 2028 | GE, YULIN | reporter.nih.gov |
| Novel Protein Biomarkers of Corticolimbic Pathophysiology in Lewy body Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $4,943,234 | September 15, 2022 | June 30, 2027 | SEYFRIED, NICHOLAS THOMAS | reporter.nih.gov |
| Assessing Novel Biomarkers for Cognitive Fluctuations in DLB | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $4,924,374 | September 1, 2025 | July 31, 2029 | PILLAI, JAGAN AYYAPPAN | reporter.nih.gov |
| Federated digital pathology platform for AD/ADRD research and diagnostics | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,861,895 | September 20, 2023 | August 31, 2028 | NELSON, PETER T. | reporter.nih.gov |
| Investigations of the protein aggregation inhibitor NU-9 and its derivatives: mode of action and impact on Alzheimer’s disease and related dementias | NIH | National Institute on Aging | 2021 to 2025 | $4,851,218 | August 1, 2019 | July 31, 2029 | OZDINLER, PEMBE HANDE | reporter.nih.gov |
| Characterizing Cognitive Decline in Late Life Depression: The ADNI-D Project | NIH | National Institute of Mental Health | 2022 to 2025 | $4,842,533 | August 1, 2013 | May 31, 2027 | MACKIN, ROBERT SCOTT | reporter.nih.gov |
| Web-based Automated Imaging Differentiation of Parkinsonism | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,837,150 | April 1, 2021 | March 31, 2027 | VAILLANCOURT, DAVID E | reporter.nih.gov |
| Vasculo-neuronal pathophysiological interface in Alzheimer’s and Atherosclerosis | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,815,513 | September 18, 2024 | August 31, 2027 | IRUELA-ARISPE, M. LUISA | reporter.nih.gov |
| Novel retinal higher-order capillary hemodynamics imaging for detecting cerebral small vessel disease | NIH | Office of the Director, National Institutes of Health | 2024 to 2025 | $4,719,171 | September 15, 2024 | September 14, 2027 | WANG, JIANHUA | reporter.nih.gov |
| Primary Progressive Aphasia: Cognition, Anatomy and Progression | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $4,705,247 | July 15, 2004 | August 31, 2025 | GORNO TEMPINI, MARIA LUISA | reporter.nih.gov |
| The BrainCellQTL consortium: QTL mapping in the human brain at the single cell level | NIH | National Institute on Aging | 2024 to 2025 | $4,701,117 | April 15, 2024 | March 31, 2029 | ROUSSOS, PANAGIOTIS | reporter.nih.gov |
| Defining the molecular spectrum of white matter vascular lesions | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,693,249 | September 17, 2024 | August 31, 2027 | HINMAN, JASON D | reporter.nih.gov |
| Brain mitochondrial PET imaging and 31P-MR spectroscopy to dissect the role of mitochondrial dysfunction in bioenergetic dysregulation in Dementia with Lewy Bodies pathogenesis | NIH | National Institute on Aging | 2023 to 2025 | $4,683,243 | September 15, 2023 | May 31, 2029 | BERMAN, SARAH B | reporter.nih.gov |
| Model-based cerebrovascular markers extracted from hemodynamic data for diagnosing MCI or AD and predicting disease progression. | NIH | National Institute on Aging | 2021 to 2022 | $4,594,525 | September 1, 2018 | May 31, 2025 | MARMARELIS, VASILIS Z | reporter.nih.gov |
| Development of a MT-stabilizing agent for the treatment of tauopathies | NIH | National Institute on Aging | 2024 to 2025 | $4,559,463 | September 1, 2024 | August 31, 2027 | CAFFREY, CONOR | reporter.nih.gov |
| An Acquisition and Analysis Pipeline for Integrating MRI and Neuropathology in TBI-related Dementia and VCID | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,539,313 | September 22, 2023 | August 31, 2028 | VAN DER KOUWE, ANDRE JAN WILLEM | reporter.nih.gov |
| Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,511,697 | January 1, 2019 | December 31, 2026 | NELSON, MARK T | reporter.nih.gov |
| African Ancestry and the Genomic Architecture of AD and Other Common Neurodegenerative Disease Neuropathologies | NIH | National Institute on Aging | 2021 to 2023 | $4,504,699 | September 15, 2016 | May 31, 2024 | BENNETT, DAVID ALAN | reporter.nih.gov |
| A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC Collaboration | NIH | National Institute on Aging | 2023 to 2025 | $4,445,528 | September 15, 2017 | June 30, 2028 | SACHDEV, PERMINDER S | reporter.nih.gov |
| Cognitive Impairment and Dementia, Vascular Brain Injury, and Atrial Myopathy: Implications for Prevention of Alzheimer's Disease-Related Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,390,219 | September 20, 2023 | August 31, 2026 | CHEN, LIN YEE | reporter.nih.gov |
| Precursors of Stroke Incidence and Prognosis | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,368,194 | December 1, 1981 | August 31, 2028 | ROMERO, JOSE RAFAEL | reporter.nih.gov |
| 5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $4,365,934 | September 15, 2017 | October 31, 2024 | VERGHESE, JOE | reporter.nih.gov |
| VCID Center Without Walls for Understanding and Leveraging Small Vessel Cerebrovascular Disease Mechanisms in ADRD | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $4,361,625 | September 24, 2024 | August 31, 2027 | LEE, JIN-MOO | reporter.nih.gov |
| Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $4,359,590 | December 1, 2016 | November 30, 2024 | GITLER, AARON D. | reporter.nih.gov |
| Spreading Tau Pathology in Non-Amnestic Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $4,306,312 | July 1, 2018 | June 30, 2028 | PHILLIPS, JEFFREY S | reporter.nih.gov |
| Consequences of Exposure to Repetitive Head Impacts Across the Lifespan | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $4,269,339 | June 1, 2025 | May 31, 2027 | MCKEE, ANN C. | reporter.nih.gov |
| Structural Biology of Alpha-Synuclein in Lewy Body Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $4,231,530 | September 30, 2018 | August 31, 2026 | KOTZBAUER, PAUL T | reporter.nih.gov |
| Microglia contribution to disease pathogenesis in C9orf72 ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,229,195 | September 1, 2021 | August 31, 2027 | SATTLER, RITA | reporter.nih.gov |
| Neuroimaging and clinical Endpoints With High-dimensional analysis Of Pathological Endophenotypes in TBI (NEW-HOPE-TBI) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $4,213,033 | August 15, 2024 | July 31, 2029 | KEENE, CHRISTOPHER DIRK | reporter.nih.gov |
| Pathogenic Mechanisms in Christianson Syndrome and NHE6-Related Disorders | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,197,634 | September 15, 2019 | June 30, 2029 | MORROW, ERIC M | reporter.nih.gov |
| Peripheral Tissue Biomarker for Premortem Diagnosis of Lewy Body Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $4,170,328 | December 15, 2021 | June 30, 2026 | CHEN, SHU G. | reporter.nih.gov |
| Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $4,141,255 | September 30, 2024 | August 31, 2029 | GOLDSTEIN, LEE E. | reporter.nih.gov |
| Cognitive Aging, Brain Morphology, and Arrhythmias in Hispanics/Latinos: Implications for Prevention and Management of Alzheimer's Disease-Related Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $4,131,388 | April 1, 2022 | March 31, 2025 | CHEN, LIN YEE | reporter.nih.gov |
| Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2025 | $4,104,231 | August 15, 2021 | April 30, 2027 | BLESSING, ESTHER MARIAN | reporter.nih.gov |
| Structural and diffusion changes of perivascular space in aging, cognitive decline and Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2025 | $4,101,683 | September 5, 2021 | June 30, 2027 | CHOUPAN, JEIRAN | reporter.nih.gov |
| Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,093,112 | September 30, 2016 | July 31, 2027 | LU, HANZHANG | reporter.nih.gov |
| Preclinical evaluation of tacrolimus in a canine model of Alzheimer's disease | NIH | National Institute on Aging | 2022 | $4,083,505 | September 15, 2017 | May 31, 2025 | HEAD, ELIZABETH | reporter.nih.gov |
| Neuro-exergaming for the Prevention and Remediation of Decline due to Parkinson's Disease: Clinical Trial of the Interactive Physical and Cognitive Exercise System (iPACES v3) | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $4,081,293 | August 11, 2023 | July 31, 2027 | GILLEN, ROBERT WILLSON | reporter.nih.gov |
| Nuclear pore complex quality control in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $4,005,112 | May 1, 2021 | April 30, 2026 | ROTHSTEIN, JEFFREY D | reporter.nih.gov |
| Vascular Pathology in Early and Asymptomatic Cerebral Amyloid Angiopathy | NIH | National Institute on Aging | 2021 to 2025 | $3,993,325 | September 30, 2014 | March 31, 2027 | VISWANATHAN, ANAND | reporter.nih.gov |
| Regulation of mRNA processing: Mechanisms and Consequences | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,993,090 | June 8, 2016 | May 31, 2026 | MANLEY, JAMES L. | reporter.nih.gov |
| Discovery of Multimodal Biomarkers for Parkinsonian Syndromes, Their Progression, and Pathological Relevance | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $3,985,569 | June 1, 2019 | May 31, 2025 | MAILMAN, RICHARD B | reporter.nih.gov |
| Building an unbiased pooled cohort for the study of lifecourse social and vascular determinants of Alzheimer's Disease and Related Disorders | NIH | National Institute on Aging | 2021 to 2025 | $3,985,562 | June 15, 2021 | March 31, 2027 | ZEKI AL HAZZOURI, ADINA | reporter.nih.gov |
| Preeclampsia and the Brain: Small vessel disease and cognitive function in early midlife | NIH | National Institute on Aging | 2022 to 2025 | $3,960,160 | February 1, 2022 | November 30, 2026 | CATOV, JANET M | reporter.nih.gov |
| Burden and change in Alzheimers disease neuropathology in aging World Trade Center responders | NIH | National Institute on Aging | 2021 to 2025 | $3,952,934 | March 15, 2021 | February 28, 2027 | CLOUSTON, SEAN | reporter.nih.gov |
| Transdisciplinary Research Accelerating Neuropathology Studies and Facilitating Open Research Methods in TBI (TRANSFORM-TBI) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $3,951,871 | June 1, 2024 | April 30, 2029 | SMITH, DOUGLAS HAMILTON | reporter.nih.gov |
| Synergistic white matter injury from diesel exhaust particulate and chronic cerebral hypoperfusion exposures: Interaction between the Nogo/NgR1 receptor pathway and extravascular fibrinogen toxicity | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,929,367 | September 20, 2022 | August 31, 2027 | MACK, WILLIAM J | reporter.nih.gov |
| Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,917,121 | February 1, 2021 | January 31, 2027 | ALOSCO, MICHAEL | reporter.nih.gov |
| Frontotemporal dementia and related disorders: transcriptomic profiling, biomarker discovery, and mechanistic insight | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,904,675 | April 15, 2021 | March 31, 2027 | VAN BLITTERSWIJK, MARKA | reporter.nih.gov |
| Mechanisms of Prion Protein Toxicity | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,903,115 | July 1, 2010 | June 30, 2026 | HARRIS, DAVID A | reporter.nih.gov |
| Depression treatment and Aβ dynamics: A study of Alzheimer’s disease risk | NIH | National Institute on Aging | 2021 to 2025 | $3,865,122 | August 15, 2021 | July 31, 2027 | POMARA, NUNZIO | reporter.nih.gov |
| Validation of Imaging and Blood-based Small Vessel VCID Biomarkers in Multiethnic Population | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,859,697 | September 30, 2021 | July 31, 2027 | WANG, DANNY JJ | reporter.nih.gov |
| PRE3BAD: Preclinical Research on Emerging Environmental Exposures, Brain Aging, and Dementia | NIH | National Institute on Aging | 2024 to 2025 | $3,859,319 | September 30, 2024 | August 31, 2029 | CAMPEN, MATTHEW J | reporter.nih.gov |
| Perivascular fibroblasts, vascular fibrosis, and their contributions to cerebral amyloid angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,851,096 | September 19, 2022 | July 31, 2027 | LIPPMANN, ETHAN | reporter.nih.gov |
| Menopausal Vasomotor Symptoms and Brain Aging in Women | NIH | National Institute on Aging | 2021 to 2025 | $3,849,407 | August 15, 2016 | June 30, 2027 | THURSTON, REBECCA C | reporter.nih.gov |
| Skin biomarkers for diagnosing and characterizing AD and ADRD | NIH | National Institute on Aging | 2021 to 2025 | $3,834,262 | September 30, 2021 | June 30, 2027 | KRAUS, ALLISON L | reporter.nih.gov |
| Synucleinopathies – Novel Targets in Early Diagnosis, Pathophysiology, and Therapeutic Approach | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,826,830 | August 1, 2015 | June 30, 2027 | SINGER, WOLFGANG | reporter.nih.gov |
| Resilience to Cognitive Decline and Resistance to Alzheimer's Disease and Related Neurodegenerative Diseases in Individuals from Colombia with Autosomal Dominant Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $3,821,618 | August 15, 2023 | July 31, 2026 | QUIROZ, YAKEEL T. | reporter.nih.gov |
| Emotion network dysfunction and decline in early frontotemporal dementia | NIH | National Institute on Aging | 2021 to 2025 | $3,811,261 | December 15, 2016 | February 28, 2027 | STURM, VIRGINIA EMILY | reporter.nih.gov |
| TDP-43 acetylation, phase separation, aggregation, and clearance by antibody-mediated degradation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,806,187 | April 1, 2021 | March 31, 2026 | CLEVELAND, DON W | reporter.nih.gov |
| Alzheimer's Disease Pathology in a Primate Model | NIH | National Institute on Aging | 2021 to 2025 | $3,764,077 | February 15, 2021 | January 31, 2027 | HOPKINS, WILLIAM D | reporter.nih.gov |
| Effect of diabetes and AD pathology on brain imaging and cognition in Latino adults | NIH | National Institute on Aging | 2022 | $3,755,733 | September 30, 2022 | August 31, 2025 | YASSINE, HUSSEIN N | reporter.nih.gov |
| Digital Biomarkers for Vascular Cognitive Decline in Patients with Minor Stroke | NIH | National Institute on Aging | 2022 to 2025 | $3,752,944 | September 10, 2022 | August 31, 2027 | MARSH, ELISABETH BREESE | reporter.nih.gov |
| Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF) | NIH | National Institute on Aging | 2021 to 2025 | $3,724,610 | September 1, 2021 | May 31, 2027 | MATHEW, JOSEPH P | reporter.nih.gov |
| Digital Accessible Remote Olfactory Mediated Health Assessments forPreclinical AD | NIH | National Institute on Aging | 2021 to 2025 | $3,718,193 | September 30, 2018 | June 30, 2027 | REINEKE, SEAN | reporter.nih.gov |
| TRP channels as fundamental sensors of the cerebral microcirculation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,709,945 | February 1, 2021 | July 31, 2024 | EARLEY, SCOTT | reporter.nih.gov |
| Elucidating the Biological Differences Between Distinct Fibrillar and Non-Fibrillar Alpha-Synuclein Inclusions in Human Stem-Cell Models | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,706,946 | July 1, 2020 | April 30, 2026 | KHURANA, VIKRAM | reporter.nih.gov |
| Reducing African Americans' Alzheimer's Disease Risk Through Exercise-MCI Cohort (RAATE-MCI) | NIH | National Institute on Aging | 2021 to 2025 | $3,689,143 | July 1, 2020 | March 31, 2027 | NEWTON, ROBERT LEE | reporter.nih.gov |
| tRNA fragments and their role in tau pathology in Alzheimer's disease and tauopathies | NIH | National Institute on Aging | 2025 | $3,672,952 | September 1, 2025 | August 31, 2029 | KRICHEVSKY, ANNA M. | reporter.nih.gov |
| Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | NIH | National Institute on Aging | 2021 to 2025 | $3,657,244 | March 1, 2021 | November 30, 2026 | KELLIS, MANOLIS | reporter.nih.gov |
| Nuclear and Glial Dysfunction in Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,647,532 | May 16, 2023 | April 30, 2031 | ROTHSTEIN, JEFFREY D | reporter.nih.gov |
| Lymphatics-Glymphatics in CNS Fluid Homeostasis | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,644,017 | April 1, 2021 | March 31, 2026 | BENVENISTE, HELENE D | reporter.nih.gov |
| IND enabling CMC/safety/toxicology studies, submission of IND and pilot Phase 1 clinical trial with PV-1950R vaccine for Lewy Body Dementia (LBD) | NIH | National Institute on Aging | 2024 to 2025 | $3,640,661 | June 5, 2024 | May 31, 2029 | AGADJANYAN, MICHAEL G | reporter.nih.gov |
| Molecular and Physiological Mechanisms of Hypertensive Cerebral Microangiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,627,088 | July 1, 2020 | April 30, 2026 | GUROL, MAHMUT EDIP | reporter.nih.gov |
| Immunovascular interactions in postoperative delirium superimposed on dementia (DSD). | NIH | National Institute on Aging | 2022 to 2025 | $3,624,866 | September 15, 2022 | August 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Dissect the mechanisms of selective regional vulnerability in Lewy Body Dementias via comparative snRNA-seq analysis | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,568,423 | July 15, 2021 | May 31, 2027 | ZHAO, GUOYAN | reporter.nih.gov |
| Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) | NIH | National Institute on Aging | 2021 to 2023 | $3,567,627 | March 15, 2019 | November 30, 2025 | DAMS-O'CONNOR, KRISTEN | reporter.nih.gov |
| Targeted Cerebral Spinal Fluid (CSF) Drug Delivery - Enclear Precision System | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $3,564,917 | January 1, 2024 | December 31, 2026 | GLICKSMAN, MARCIE A | reporter.nih.gov |
| Region-Specific Vulnerability of the Lewy Body Dementia's Brain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,557,900 | August 1, 2021 | June 30, 2027 | NA, CHAN-HYUN | reporter.nih.gov |
| Advanced MRI studies of cerebrovascular and lymphatic abnormalities in LRRK2 mouse models of Parkinson's disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,536,285 | April 1, 2021 | March 31, 2027 | SMITH, WANLI W | reporter.nih.gov |
| Assessing the Role of Sex-Specific Genetic Drivers of Cerebrovascular Disease in the Alzheimer's Disease Brain | NIH | National Institute on Aging | 2025 | $3,531,593 | September 1, 2025 | August 31, 2029 | DUMITRESCU, LOGAN C | reporter.nih.gov |
| SARS-CoV-2 and Precursors of Alzheimer's Disease and Related Dementias: An Ultrahigh Field (7T) MRI Study in a Diverse Multinational Cohort | NIH | National Institute on Aging | 2021 | $3,529,440 | September 1, 2021 | August 31, 2025 | SESHADRI, SUDHA | reporter.nih.gov |
| Endolysosomal defects in secretory autophagy and microglial toxicity in FTD | NIH | National Institute on Aging | 2021 to 2025 | $3,491,522 | September 15, 2017 | March 31, 2027 | HUANG, ERIC J | reporter.nih.gov |
| SPRINT MIND 2020 | NIH | National Institute on Aging | 2021 to 2023 | $3,485,934 | June 15, 2017 | May 31, 2025 | REBOUSSIN, DAVID M | reporter.nih.gov |
| Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,480,622 | September 29, 2021 | July 31, 2027 | ARFANAKIS, KONSTANTINOS | reporter.nih.gov |
| Construction of an Integrated Immune - Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $3,475,569 | September 20, 2019 | May 31, 2024 | TSAI, LI-HUEI | reporter.nih.gov |
| Resolving the function of progranulin in lysosomal lipid metabolism and the etiology of Alzheimer's disease and frontotemporal dementia | NIH | National Institute on Aging | 2022 to 2025 | $3,471,933 | September 1, 2022 | August 31, 2027 | KUKAR, THOMAS L | reporter.nih.gov |
| More than a Movement Disorder: Applying Palliative Care to Parkinson's Disease and Lewy Body Dementias | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,433,868 | September 15, 2016 | September 30, 2026 | KLUGER, BENZI M | reporter.nih.gov |
| Role of Fibrinogen in Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,431,479 | April 1, 2018 | July 31, 2028 | STRICKLAND, SIDNEY | reporter.nih.gov |
| Biological drivers of sex differences in frontotemporal dementia | NIH | National Institute on Aging | 2025 | $3,427,292 | September 15, 2025 | August 31, 2029 | CASALETTO, KAITLIN B | reporter.nih.gov |
| Brain Glycogen-Metabolism,Mechanisms, and Therapeutic Potential | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,404,071 | May 15, 2020 | April 30, 2028 | GENTRY, MATTHEW S. | reporter.nih.gov |
| The Role of PAI-1 in Cerebral Microvascular Dysfunction and the Development of Alzheimer’s Disease Neuropathology | NIH | National Institute on Aging | 2021 to 2025 | $3,397,256 | September 1, 2021 | June 30, 2027 | LAWRENCE, DANIEL A | reporter.nih.gov |
| Blood-based AD biomarkers profile in CAPCOG-TBI study | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,393,269 | September 1, 2023 | May 31, 2028 | DING, KAN | reporter.nih.gov |
| Metabolic and neural activity normalization by cerebral blood flow increase in AD/ADRD models | NIH | National Institute on Aging | 2023 to 2025 | $3,391,148 | April 15, 2023 | January 31, 2028 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Protein aggregation in inclusion body and myofibrillar myopathies | NIH | National Institute on Aging | 2021 to 2025 | $3,388,405 | January 1, 2009 | March 31, 2029 | WEIHL, CONRAD C | reporter.nih.gov |
| Defining short RNA therapeutics that combat TDP-43 proteinopathy connected to AD and ADRDs. | NIH | National Institute on Aging | 2025 | $3,360,074 | September 15, 2025 | August 31, 2029 | SHORTER, JAMES | reporter.nih.gov |
| Sex Differences in Inflammation Across the Lifespan | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,353,112 | May 1, 2023 | April 30, 2031 | MCCULLOUGH, LOUISE D. | reporter.nih.gov |
| BRain Aging and Cognition in Epilepsy (BRACE): A longitudinal investigation of vascular, genetic, and biomarker risk profiles in elderly patients with epilepsy | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,346,371 | September 1, 2021 | February 28, 2027 | MCDONALD, CARRIE R | reporter.nih.gov |
| Small Molecule Ligands Targeting Pathological Tau Signaling In AD And Related Dementias | NIH | National Institute on Aging | 2025 | $3,336,256 | September 1, 2025 | August 31, 2029 | BRADY, SCOTT THOMAS | reporter.nih.gov |
| MAP4K3 regulation of cellular stress response pathways in health and disease | NIH | National Institute on Aging | 2022 to 2025 | $3,333,247 | December 1, 2008 | August 31, 2027 | LA SPADA, ALBERT R | reporter.nih.gov |
| Multiethnic Validation of VCID Biomarkers in South Texas | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,325,938 | September 30, 2021 | July 31, 2027 | SATIZABAL, CLAUDIA L | reporter.nih.gov |
| Drivers of Pathological Tau Aggregation | NIH | National Institute on Aging | 2021 to 2025 | $3,324,711 | April 15, 2017 | March 31, 2027 | KOSIK, KENNETH STEPHEN | reporter.nih.gov |
| Investigating aberrant vesicular degradation and lipid metabolism in neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,323,710 | August 15, 2025 | July 31, 2029 | BOSCO, DARYL ANGELA | reporter.nih.gov |
| Locus Coeruleus Imaging Markers in Preclinical Alzheimers disease, Cerebrovascular Disease and Cognitive Decline | NIH | National Institute on Aging | 2024 to 2025 | $3,322,482 | April 1, 2023 | March 31, 2029 | NATION, DANIEL A | reporter.nih.gov |
| Innate Immunity Stimulation Effects on Biomarkers, Cognition, and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAA | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,321,272 | July 15, 2022 | June 30, 2027 | SCHOLTZOVA, HENRIETA | reporter.nih.gov |
| Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $3,312,473 | September 5, 2021 | June 30, 2026 | DING, YU-SHIN | reporter.nih.gov |
| ARIA Pathophysiology Characterized by in vivo Neuroimaging, Plasma Biomarkers and Post-Mortem Proteomics | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,310,951 | June 4, 2025 | May 31, 2027 | WISNIEWSKI, THOMAS M | reporter.nih.gov |
| Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and Inattention | NIH | National Institute on Aging | 2022 to 2025 | $3,308,332 | August 1, 2022 | April 30, 2027 | DEVINNEY, MICHAEL JOSEPH | reporter.nih.gov |
| Neurodevelopment in children from families with genetic frontotemporal dementia and Alzheimer’s disease | NIH | National Institute on Aging | 2022 to 2025 | $3,300,813 | February 15, 2022 | January 31, 2027 | LEE, SUZEE EURIE | reporter.nih.gov |
| Role of GPR39 in Aging-Related Vascular Cognitive Impairment (VCI) | NIH | National Institute on Aging | 2022 to 2025 | $3,287,439 | September 15, 2022 | August 31, 2027 | ALKAYED, NABIL J | reporter.nih.gov |
| The role of blood and brain 5-hydroxymethylcytosine in linking vascular risk factors to ADRD in older White and Black persons | NIH | National Institute on Aging | 2021 | $3,275,232 | August 15, 2021 | July 31, 2024 | ARVANITAKIS, ZOE | reporter.nih.gov |
| Brain Digital Slide Archive: An Open Source Platform for data sharing and analysis of digital neuropathology | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,258,926 | September 19, 2023 | August 31, 2028 | GUTMAN, DAVID ANDREW | reporter.nih.gov |
| Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $3,258,324 | September 30, 2018 | August 31, 2024 | FITZPATRICK, ANTHONY WILLIAM PAUL | reporter.nih.gov |
| Investigating Dysregulation of Stress-related Ribonucleoprotein Granules and Functions of Associated RNA-binding Proteins in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,254,207 | February 1, 2019 | November 30, 2028 | WANG, JIOU | reporter.nih.gov |
| Microglia-Amyloid interactions in delirium superimposed on dementia | NIH | National Institute on Aging | 2021 to 2025 | $3,246,663 | September 15, 2017 | December 31, 2027 | TERRANDO, NICCOLO | reporter.nih.gov |
| Role of endothelium in pathogenesis of cerebral amyloid angiopathy | NIH | National Institute on Aging | 2021 to 2025 | $3,245,352 | September 1, 2021 | June 30, 2026 | KATUSIC, ZVONIMIR S | reporter.nih.gov |
| ApoE4, Neurovascular Injury and Cognitive Impairment | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,244,519 | April 1, 2022 | March 31, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Investigating the role of TMEM106b genetics and pathology in Alzheimer’s disease, LATE and FTLD | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,221,644 | September 22, 2023 | August 31, 2028 | PETRUCELLI, LEONARD | reporter.nih.gov |
| Cerebral hemodynamic impairment in symptomatic and asymptomatic Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,221,061 | February 1, 2022 | January 31, 2027 | QIU, DEQIANG | reporter.nih.gov |
| Longitudinal multi-modality imaging in non-fluent/agrammatic primary progressive aphasia | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $3,217,385 | July 1, 2013 | June 30, 2028 | WHITWELL, JENNIFER LOUISE | reporter.nih.gov |
| Characterization of Antigen-Specific Immune Response in ALS | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,213,011 | August 11, 2025 | July 31, 2029 | ELYAMAN, WASSIM | reporter.nih.gov |
| Vascular contribution to white matter lesions and motor dysfunction in AD and ADRD | NIH | National Institute on Aging | 2022 to 2025 | $3,210,645 | September 15, 2022 | August 31, 2027 | AHN, HYUNG JIN | reporter.nih.gov |
| A randomized, double blind, placebo-controlled study to evaluate the impact of Nilotinib treatment on safety, tolerability, pharmacokinetics and biomarkers in Dementia with Lewy Bodies (DLB) | NIH | National Institute on Aging | 2021 to 2022 | $3,210,062 | July 1, 2019 | April 30, 2025 | MOUSSA, CHARBEL | reporter.nih.gov |
| Genetic Contributions to Phenotypic Heterogeneity in the ALS-FTD Spectrum | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,204,260 | August 1, 2025 | July 31, 2029 | MCMILLAN, COREY T | reporter.nih.gov |
| RCT Targeting Cognition in Early Alzheimer's Disease by Improving Sleep with Trazodone (Rest) | NIH | National Institute on Aging | 2021 to 2024 | $3,203,115 | September 15, 2021 | August 31, 2026 | GREENBERG, BARRY DAVID | reporter.nih.gov |
| Characterization of relationship between tau pathology and neurodegeneration in Alzheimer's disease using multimodal imaging | NIH | National Institute on Aging | 2022 to 2025 | $3,200,041 | April 15, 2022 | January 31, 2027 | DAS, SANDHITSU | reporter.nih.gov |
| Diagnostic and prognostic certainty in behavioral variant frontotemporal dementia | NIH | National Institute on Aging | 2021 to 2025 | $3,196,474 | August 15, 2020 | April 30, 2027 | PERRY, DAVID C | reporter.nih.gov |
| Effects of vascular risk factors on risk for dementia and stroke after late-onset epilepsy (EpilepsyCOG) | NIH | National Institute on Aging | 2022 to 2025 | $3,188,533 | July 1, 2022 | March 31, 2027 | CHOI, HYUNMI | reporter.nih.gov |
| Novel Imaging and Biofluid Biomarkers of Small Vessel Cerebrovascular Disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,180,774 | September 29, 2021 | July 31, 2027 | KRAMER, JOEL H | reporter.nih.gov |
| Spatial organization and conformational ensembles of amyloids inside cells | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,178,675 | August 13, 2025 | July 31, 2029 | FREDERICK, KENDRA KING | reporter.nih.gov |
| Cerebrovascular Remodeling and Neurodegenerative Changes in Alzheimer's Disease | NIH | National Institute on Aging | 2022 to 2025 | $3,178,600 | February 1, 2022 | January 31, 2027 | ZHANG, YANHANG KATHERINE | reporter.nih.gov |
| Deep Phenotypic Characterization of Prodromal Dementia with Lewy Bodies | NIH | National Institute on Aging | 2022 | $3,171,435 | September 30, 2022 | August 31, 2025 | GALVIN, JAMES E | reporter.nih.gov |
| Contributions of modifiable physical attributes to cognitive and brain aging | NIH | National Institute on Aging | 2021 to 2025 | $3,167,967 | May 15, 2021 | April 30, 2027 | HAYES, SCOTT M | reporter.nih.gov |
| Large-scale harmonization and integration of multi-modal ADNI data for the early detection of Alzheimer's disease and related dementias | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,158,935 | July 15, 2022 | May 31, 2027 | VARGHESE, BINO ABEL | reporter.nih.gov |
| Carotid Revascularization and Medical Management for Asymptomatic CarotidStenosis Trial - Hemodynamics (CREST-H) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,153,445 | May 15, 2017 | July 31, 2027 | MARSHALL, RANDOLPH S | reporter.nih.gov |
| Upstream pathogenesis in familial and sporadic frontotemporal dementia and motor neuron disease | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,153,019 | July 1, 2018 | July 31, 2029 | SEELEY, WILLIAM W | reporter.nih.gov |
| Functional And Multi-Omics Approaches To Elucidate The Regulation Of Proteasome Complex In Neurodegenerative Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,145,300 | August 1, 2025 | July 31, 2029 | MYEKU, NATURA | reporter.nih.gov |
| POINTER-zzz: Sleep Ancillary to U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $3,144,541 | August 15, 2019 | May 31, 2025 | BAKER, LAURA D. | reporter.nih.gov |
| Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease and Related Disorders | NIH | National Institute on Aging | 2022 to 2025 | $3,140,565 | June 1, 2022 | March 31, 2027 | KREILING, JILL | reporter.nih.gov |
| Longitudinal Multi-modal Imaging in Progressive Supranuclear Palsy Syndromes | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,134,730 | September 15, 2015 | August 31, 2025 | WHITWELL, JENNIFER LOUISE | reporter.nih.gov |
| Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementia | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $3,134,584 | January 1, 2018 | December 31, 2023 | NICHOLS, COLIN G | reporter.nih.gov |
| Epitope-Specific Targeting of Tau Aggregates | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,132,930 | September 1, 2011 | May 31, 2027 | SIGURDSSON, EINAR M | reporter.nih.gov |
| Investigating Resistance and Resilience Mechanisms in Alzheimer’s Disease | NIH | National Institute on Aging | 2021 to 2025 | $3,131,976 | September 15, 2017 | February 29, 2028 | VEMURI, PRASHANTHI | reporter.nih.gov |
| Alzheimer's Abeta, Tau, Apolipoproteins and Blood-brain barrier | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,119,037 | September 1, 1995 | February 28, 2026 | YASSINE, HUSSEIN N | reporter.nih.gov |
| Longitudinal MRI Investigation of Traumatic Microvascular Injury | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,116,729 | February 15, 2022 | January 31, 2027 | WARE, JEFFREY B | reporter.nih.gov |
| Impairment of Ischemia-induced Vascular Functions by PS1 FAD Mutants | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,116,100 | January 15, 2021 | December 31, 2025 | GEORGAKOPOULOS, ANASTASIOS | reporter.nih.gov |
| Alzheimer's Disease Hallmark Pathology and Associated Inflammation in the Retina | NIH | National Institute on Aging | 2021 to 2025 | $3,113,565 | April 1, 2018 | June 30, 2028 | KORONYO-HAMAOUI, MAYA | reporter.nih.gov |
| Blood Pressure and ADRD in African Americans: the Jackson Heart Study | NIH | National Institute on Aging | 2021 to 2022 | $3,111,832 | September 15, 2019 | August 31, 2022 | PALTA, PRIYA | reporter.nih.gov |
| Hippocampal iPSC-Derived Assembloids to Model Interneuron and Circuit Vulnerability in Genetically-Encoded Amnestic and Behavioral Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,109,857 | August 1, 2025 | July 31, 2029 | REXACH, JESSICA E | reporter.nih.gov |
| Modeling the role of age at traumatic brain injury in the development of Alzheimer's Disease and related dementias | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $3,109,079 | August 1, 2024 | July 31, 2027 | OBENAUS, ANDRE | reporter.nih.gov |
| Integrating Spatial Multi-omics and Clinical Covariates to Identify Mechanisms of Disease in ALS-FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,108,178 | August 15, 2020 | April 30, 2026 | PHATNANI, HEMALI | reporter.nih.gov |
| Recovery of StrokE - Longitudinal Assessment With Neuroimaging (ROSE LAWN) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,104,674 | December 15, 2020 | November 30, 2025 | WOO, DANIEL | reporter.nih.gov |
| Advanced MR Imaging of Olfactory Impairment in Prodromal Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $3,102,717 | May 1, 2020 | February 28, 2026 | HUA, JUN | reporter.nih.gov |
| Developing Gyrencephalic Models of TBI-Induced ADRD Neuropathology | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $3,102,638 | August 15, 2024 | July 31, 2027 | JOHNSON, VICTORIA ELEANOR | reporter.nih.gov |
| Optimization of an at-home continuous multi-domain monitoring and assessment system to improve Alzheimer's and related disorders clinical trials | NIH | National Institute on Aging | 2022 to 2024 | $3,094,239 | February 1, 2022 | November 30, 2025 | FRYE, LAWRENCE J | reporter.nih.gov |
| Single molecule study of C9ORF72 repeat RNA metabolisms in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,085,325 | March 1, 2020 | May 31, 2029 | SUN, SHUYING | reporter.nih.gov |
| Mechanism of ALS/FTD determined by multimodal single cell spatial transcriptomics | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,081,936 | September 12, 2025 | June 30, 2029 | CLEVELAND, DON W | reporter.nih.gov |
| Disease Mechanism and Therapy in TDP-43 Proteinopathies and Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,081,573 | April 1, 1989 | August 31, 2027 | CLEVELAND, DON W | reporter.nih.gov |
| Immune Cells in Alzheimer’s Disease and Related Dementias in the Jackson Heart Study | NIH | National Institute on Aging | 2022 to 2025 | $3,079,808 | March 1, 2022 | November 30, 2026 | RAFFIELD, LAURA M | reporter.nih.gov |
| Cerebrovascular contributions to Alzheimer's disease in adults with Down Syndrome | NIH | National Institute on Aging | 2022 | $3,079,273 | September 30, 2022 | August 31, 2025 | BRICKMAN, ADAM M | reporter.nih.gov |
| Covert Cerebrovascular Disease Detected by Artificial Intelligence (C2D2AI): A Platform for Pragmatic Evidence Generation for Stroke and Dementia Prevention | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $3,076,281 | February 1, 2023 | January 31, 2026 | KENT, DAVID M | reporter.nih.gov |
| Preclinical Markers of Parkinsonism | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $3,073,020 | August 1, 2021 | June 30, 2027 | VAILLANCOURT, DAVID E | reporter.nih.gov |
| Novel Volumetric Optical Microscopy to Unravel Cerebral Microvascular Architecture and the Role in Functional Neuroimaging in Human Alzheimer's Disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $3,069,316 | August 1, 2022 | July 31, 2027 | WANG, HUI | reporter.nih.gov |
| Production and Distribution of well-characterized polymorphic variants of alpha-synuclein aggregates | NIH | National Institute on Aging | 2022 to 2025 | $3,065,392 | September 30, 2022 | May 31, 2027 | SOTO, CLAUDIO | reporter.nih.gov |
| Anxiety and depression in a nonhuman primate model of synucleinopathy | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,064,072 | August 4, 2025 | July 31, 2029 | EMBORG, MARINA | reporter.nih.gov |
| Efflux Route Responses of Cerebral Waste Clearance During Progression of Alzheimer’s Disease | NIH | National Institute on Aging | 2025 | $3,062,355 | September 15, 2025 | August 31, 2029 | JIANG, QUAN | reporter.nih.gov |
| Molecular characterization of extracellular vesicles for the spread of misfolded tau protein | NIH | National Institute on Aging | 2021 to 2025 | $3,058,838 | May 15, 2021 | April 30, 2027 | IKEZU, TSUNEYA | reporter.nih.gov |
| Single-cell multi-region transcriptional and epigenomic dissection of VCID. | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $3,058,535 | September 15, 2022 | August 31, 2025 | KELLIS, MANOLIS | reporter.nih.gov |
| The Amylin Dyshomeostasis Hypothesis of Vascular Contributions to Cognitive Impairment and Dementia (VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,056,084 | April 1, 2020 | March 31, 2026 | DESPA, FLORIN | reporter.nih.gov |
| Regulation of human tau expression and tauopathy by alpha-synuclein | NIH | National Institute on Aging | 2022 to 2025 | $3,043,872 | June 1, 2022 | March 31, 2027 | LEE, MICHAEL K | reporter.nih.gov |
| An assistive-technology based Caregiver Training Program (CTP) to enhance caregiver effectiveness, well-being, and quality of life, which will improve overall care for individuals living with AD/ADRD. | NIH | National Institute on Aging | 2022 to 2024 | $3,039,350 | May 15, 2022 | May 31, 2025 | GOLDEN, MATTHEW | reporter.nih.gov |
| SARS-CoV-2 initiation and acceleration of AD pathology in the setting of endogenous and exogenous risk factors | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,039,032 | August 15, 2025 | July 31, 2029 | ANNAPRAGADA, ANANTH V | reporter.nih.gov |
| Intracranial arterial compliance, cerebral blood flow, and dementia risk in older adults with type 2 diabetes | NIH | National Institute on Aging | 2021 to 2024 | $3,038,302 | May 1, 2020 | February 28, 2026 | BANGEN, KATHERINE | reporter.nih.gov |
| Development of an ophthalmic diagnostic probe for cerebral amyloid angiopathy in patients | NIH | National Institute on Aging | 2021 to 2022 | $3,033,670 | June 1, 2021 | May 31, 2024 | SARRAF, STELLA | reporter.nih.gov |
| Aging Research Characterizing Health Equity via Social determinants (ARCHES) | NIH | National Institute on Aging | 2021 to 2024 | $3,033,223 | September 1, 2021 | May 31, 2026 | BABULAL, GANESH M | reporter.nih.gov |
| Molecular Genetic Insight into Neurodegenerative Disease from Drosophila | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $3,032,672 | December 1, 2016 | November 30, 2025 | BONINI, NANCY M | reporter.nih.gov |
| Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimer’s Disease | NIH | National Center for Complementary & Integrative Health | 2021 to 2025 | $3,032,391 | May 15, 2021 | April 30, 2026 | TSAI, LI-HUEI | reporter.nih.gov |
| Investigating the Causal Role of Particulate Matter Components on Lewy Body Dementia: Integrating Epidemiologic and Mechanistic Evidence | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $3,013,265 | August 1, 2025 | July 31, 2029 | PARKS, ROBBIE M | reporter.nih.gov |
| Gas-free cerebrovascular reactivity (CVR) MRI in vascular cognitive impairment | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,984,490 | August 16, 2021 | July 31, 2027 | LIU, PEIYING | reporter.nih.gov |
| Differential diagnosis of Parkinson's and multiple system atrophy in non-human primate models using a novel a-synuclein retinal contrast agent and AI-assisted analytics | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,977,682 | September 23, 2021 | August 31, 2024 | SARRAF, STELLA | reporter.nih.gov |
| Mechanisms of gene-environment interaction in developmental lead exposure leading to Alzheimer's disease phenotypes | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,975,224 | September 20, 2022 | August 31, 2027 | FREEMAN, JENNIFER L. | reporter.nih.gov |
| Safety and Tolerability Studies for an Anti-Fibrin P2 Monoclonal Antibody for the Treatment of Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $2,970,786 | September 30, 2021 | August 31, 2024 | KANTOR, AARON B | reporter.nih.gov |
| Single-Nuclei Multiomic Analysis of DLB Progression | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,970,479 | August 17, 2022 | July 31, 2027 | KIM, YOON-SEONG | reporter.nih.gov |
| Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communities | NIH | National Institute on Aging | 2022 to 2025 | $2,961,521 | August 15, 2022 | April 30, 2027 | MANTYH, WILLIAM G | reporter.nih.gov |
| Air pollution and early signs of dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,959,713 | September 30, 2022 | August 31, 2027 | HUELS, ANKE | reporter.nih.gov |
| Brain signature of SARS-CoV-2 Infection and its impact on long-term cognitive functioning in older adults | NIH | National Institute on Aging | 2022 to 2025 | $2,954,828 | July 1, 2022 | June 30, 2027 | SCHIFITTO, GIOVANNI | reporter.nih.gov |
| Investigating the Novel Disease Pathways Associated with C9orf72-Linked ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,951,882 | May 15, 2015 | April 30, 2030 | WANG, JIOU | reporter.nih.gov |
| Development and Evaluation of Portable Compendium of Psychophysical and Physiological Tests for Alzheimer's Disease and Related Dementias (ADRD) | NIH | National Institute on Aging | 2023 to 2025 | $2,947,375 | August 1, 2023 | April 30, 2026 | NWAOKOBIA, CHARLES CHIEDU | reporter.nih.gov |
| Cell and Network Disruptions and Associated Pathogenenesis in Tauopathy and Down Syndrome | NIH | National Institute on Aging | 2021 to 2024 | $2,943,744 | April 15, 2020 | March 31, 2026 | FINKBEINER, STEVEN M | reporter.nih.gov |
| Global Brain Health Predictors of Post-Stroke Sensorimotor Recovery using AI-Enhanced Clinical MRIs | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,942,690 | April 1, 2020 | June 30, 2029 | LIEW, SOOK-LEI | reporter.nih.gov |
| Multi-site longitudinal Integrated Neurocognitive and Sleep-Behavior Profiler for the Endophenotypic Classification of Dementia Subtypes (INSPECDS) | NIH | National Institute on Aging | 2022 to 2024 | $2,933,352 | September 30, 2016 | May 31, 2026 | BERKA, CHRIS | reporter.nih.gov |
| Stroke Connectome MRI Biomarkers for VCID Risk Assessment | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,928,784 | April 1, 2022 | March 31, 2027 | NAIR, VEENA A | reporter.nih.gov |
| Functional and Pathological Interactions of TDP-43 | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,925,557 | April 1, 2020 | March 31, 2025 | FAWZI, NICOLAS LUX | reporter.nih.gov |
| Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $2,924,902 | September 15, 2022 | August 31, 2027 | DUNCKLEY, TRAVIS | reporter.nih.gov |
| Development of a Blood-based Test for Identifying Synucleinopathy in Patients with Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,919,989 | September 23, 2022 | August 31, 2026 | EITAN, EREZ | reporter.nih.gov |
| Molecular Neurobiology of Human Opioid Use Disorder | NIH | National Institute on Drug Abuse | 2021 to 2025 | $2,918,959 | July 15, 2021 | March 31, 2027 | HURD, YASMIN L. | reporter.nih.gov |
| Brainstem-based imaging biomarkers of premanifest synucleinopathy | NIH | National Institute on Aging | 2021 to 2024 | $2,913,904 | May 15, 2020 | April 30, 2026 | BIANCIARDI, MARTA | reporter.nih.gov |
| Longitudinal multi-omic biomarkers for neurocognitive decline prior to dementia onset | NIH | National Institute on Aging | 2024 to 2025 | $2,904,500 | September 30, 2024 | June 30, 2029 | HARRIS, SARAH ELIZABETH | reporter.nih.gov |
| Defining mechanisms underlying C9orf72-associated frontotemporal dementia with C. elegans and mammalian models | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,904,236 | February 1, 2022 | January 31, 2027 | KALB, ROBERT G | reporter.nih.gov |
| Dietary Sodium, Neurovascular Dysfunction and Cerebrovascular Risk | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,895,400 | December 1, 2015 | June 30, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Development of a SYF2 antisense oligonucleotide treatment for ALS and FTD | NIH | National Institute on Aging | 2023 to 2024 | $2,894,619 | August 1, 2023 | July 31, 2025 | ALWORTH, SAMUEL V | reporter.nih.gov |
| Single Cell Characterization of FTLD-GRN | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,891,009 | September 15, 2022 | August 31, 2025 | HUANG, ERIC J | reporter.nih.gov |
| Roles of Gray Matter Brain Aging and Small Vessel Disease in AD Pathophysiology | NIH | National Institute on Aging | 2024 to 2025 | $2,872,909 | March 1, 2005 | February 28, 2027 | AIZENSTEIN, HOWARD J | reporter.nih.gov |
| Molecular and genetic studies of NMNAT2 in neuroprotection | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,871,601 | September 15, 2014 | March 31, 2027 | LU, HUI-CHEN | reporter.nih.gov |
| Multiethnic machine learning brain signatures of ADRD | NIH | National Institute on Aging | 2022 to 2025 | $2,860,890 | September 1, 2022 | June 30, 2027 | HABES, MOHAMAD | reporter.nih.gov |
| Elucidating Molecular Drivers of Aging and Alzheimer's Disease via Multimodal Imaging Mass Spectrometry | NIH | National Institute on Aging | 2022 to 2025 | $2,856,050 | September 1, 2022 | June 30, 2027 | SPRAGGINS, JEFFREY M | reporter.nih.gov |
| Auracle: An AI-Enabled Telecare System to Support the Independence and Safety of Individuals with AD/ADRD and Other Dementias | NIH | National Institute on Aging | 2021 to 2023 | $2,851,310 | September 1, 2021 | August 31, 2025 | FAUCI, MARK A | reporter.nih.gov |
| Investigation of the role of ATXN1 in oligodendroglia and neurodegenerative diseases | NIH | National Institute on Aging | 2022 to 2025 | $2,847,875 | March 1, 2022 | December 31, 2026 | LIM, JANGHOO | reporter.nih.gov |
| The interplay between Tau and ncRNAs – genomic and epigenomic clues to early AD pathogenesis | NIH | National Institute on Aging | 2022 to 2025 | $2,845,617 | June 15, 2022 | March 31, 2027 | KOLDAMOVA, RADOSVETA | reporter.nih.gov |
| Are there ethnic differences in brain amyloid and tau in the seventh decade of life? | NIH | National Institute on Aging | 2021 to 2022 | $2,845,324 | August 1, 2017 | April 30, 2024 | LUCHSINGER, JOSE ALEJANDRO | reporter.nih.gov |
| The role of a metazoan-specific PQC system in protecting against TDP-43 proteinopathies | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,817,215 | August 7, 2025 | July 31, 2029 | YANG, XIAOLU | reporter.nih.gov |
| The relationship between ocus-coeruleus-norepinephrine network and neurovascular coupling in health and disease | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,813,759 | August 15, 2025 | July 31, 2029 | TRAN, CAM HA THAI | reporter.nih.gov |
| An Epidemiologic Study of Disparities in Sleep and Cognition in Older Adults (DISCO) | NIH | National Institute on Aging | 2021 to 2023 | $2,797,984 | July 1, 2019 | March 31, 2024 | KNUTSON, KRISTEN | reporter.nih.gov |
| Pathological mechanisms of white matter hyperintensities | NIH | National Institute on Aging | 2021 to 2024 | $2,796,704 | September 1, 2021 | January 15, 2025 | RANE LEVENDOVSZKY, SWATI | reporter.nih.gov |
| Modeling and Therapeutic Approaches for Genetic Vasculopathies | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,784,876 | September 20, 2022 | July 31, 2027 | MUSOLINO, PATRICIA L | reporter.nih.gov |
| Contact System and Alzheimer's Disease: Mechanism and Therapeutic Potential | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,781,611 | April 15, 2018 | August 31, 2029 | STRICKLAND, SIDNEY | reporter.nih.gov |
| Investigating the Microvascular Mechanisms of O2 Supply-Demand Mismatch in Small Vessel Disease using Novel High-Resolution Optical Imaging | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,778,545 | May 1, 2020 | April 30, 2026 | SAKADZIC, SAVA | reporter.nih.gov |
| BBB Dysfunction in Post-Stroke Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,776,180 | September 15, 2022 | August 31, 2027 | BUCKWALTER, MARION S | reporter.nih.gov |
| Reinforcement Mechanisms for Learning Vocal Behaviors - Renewal - 1 | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,764,385 | April 1, 2018 | August 31, 2028 | ROBERTS, TODD F | reporter.nih.gov |
| Favorable cardiovascular health, connectome integrity, and ADRD clinical outcomes and pathologic underpinnings in a diverse cohort. | NIH | National Institute on Aging | 2022 to 2025 | $2,728,963 | August 1, 2022 | July 31, 2028 | LAMAR, MELISSA | reporter.nih.gov |
| Brain Glycogen - Metabolism, Mechanisms, and Therapeutic Potential | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,726,725 | May 15, 2020 | August 12, 2022 | GENTRY, MATTHEW S. | reporter.nih.gov |
| Vitamin K and D and Cognitive Impairment in Older Adults | NIH | National Institute on Aging | 2022 to 2025 | $2,723,572 | September 1, 2016 | March 31, 2027 | BOOTH, SARAH LOUISE | reporter.nih.gov |
| Metabolic and Vascular Factors in tau pathogenesis | NIH | National Institute on Aging | 2021 to 2024 | $2,720,466 | September 15, 2020 | May 31, 2025 | FRAUTSCHY, SALLY ANN | reporter.nih.gov |
| Postsynaptic kinase/phosphatase networks in amyloid beta-induced synaptic dysfunction | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,718,318 | September 30, 2018 | August 31, 2029 | DELL'ACQUA, MARK L | reporter.nih.gov |
| Validating Secretory Autophagy as a Therapeutic Strategy for Diverse Forms of ALS and FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,714,836 | July 1, 2017 | June 30, 2026 | ICHIDA, JUSTIN KAWIKA | reporter.nih.gov |
| Regulation of Pathological Tau Transmission by Soluble Tau Post-Translational Modifications | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,714,628 | July 1, 2022 | April 30, 2027 | PENG, CHAO | reporter.nih.gov |
| Role of TRIM11 in regulating TDP-43 and FUS | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,709,695 | September 5, 2025 | August 31, 2029 | YANG, XIAOLU | reporter.nih.gov |
| Metabolic and Hormonal Mechanisms of VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,707,906 | April 15, 2019 | August 31, 2029 | ZULOAGA, KRISTEN LEANNE | reporter.nih.gov |
| Role of Endothelial K+ Channels in Age-Related Dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,707,384 | May 1, 2022 | April 30, 2027 | BEHRINGER, ERIK J. | reporter.nih.gov |
| StAtins Use in intRacereberal hemorrhage patieNts MRI (SATURN MRI) Ancillary Study | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,705,364 | August 15, 2021 | July 31, 2025 | SELIM, MAGDY H | reporter.nih.gov |
| Establishment of a Human Microphysiological System to Elucidate Cellular Mechanisms Underlying Vulnerability to AD | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,683,965 | May 1, 2025 | April 30, 2028 | YOUNG-PEARSE, TRACY L | reporter.nih.gov |
| Structure-function relationships in alpha-synuclein strain biology | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,674,385 | August 15, 2025 | July 31, 2029 | WOERMAN, AMANDA L. | reporter.nih.gov |
| Concordance of TDP-43 Inclusions with Cortical Atrophy and Clinical Phenotype | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,671,684 | August 1, 2014 | March 31, 2026 | GEULA, CHANGIZ | reporter.nih.gov |
| Development of an UNC13A antisense oligonucleotide treatment for ALS and FTD | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $2,670,896 | August 1, 2023 | July 31, 2025 | CHANG, WEN-HSUAN | reporter.nih.gov |
| Identifying Factors Predicting ACcurately End-of-Life in Dementia with Lewy Bodies and Promoting Quality End-of-Life Experiences: the PACE-DLB Study | NIH | National Institute on Aging | 2021 to 2024 | $2,662,829 | September 15, 2020 | April 30, 2026 | ARMSTRONG, MELISSA JO | reporter.nih.gov |
| Adding technology that will enhance commercialization of our neuroscience-based innovative assistive technology platform for living with Alzheimer's disease and Alzheimer's disease related dementia | NIH | National Institute on Aging | 2024 to 2025 | $2,660,575 | May 15, 2024 | April 30, 2027 | GOLDEN, MATTHEW | reporter.nih.gov |
| Mechanisms of Novel Regulators of Proteotoxicity and Quality Control Associated with ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,659,547 | August 15, 2011 | February 28, 2027 | WANG, JIOU | reporter.nih.gov |
| Enhancing gamma band response to improve working memory in individuals with mild cognitive impairment | NIH | National Institute on Aging | 2021 to 2024 | $2,658,625 | April 1, 2020 | March 31, 2026 | SINGH, FIZA | reporter.nih.gov |
| Supplement: Stalled capillary flow affects protein clearance by modulating interstitial fluid flow | NIH | National Institute on Aging | 2021 to 2022 | $2,646,437 | May 15, 2015 | April 30, 2024 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Underlying Mechanisms in CADASIL | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,643,847 | April 20, 2021 | March 31, 2026 | IRUELA-ARISPE, M. LUISA | reporter.nih.gov |
| Whole blood filter paper assay for Alzheimers Disease | NIH | National Institute on Aging | 2023 to 2024 | $2,638,530 | August 1, 2019 | August 31, 2025 | SELIGMANN, BRUCE E. | reporter.nih.gov |
| Microbiome-gut-brain dysfunction in prodromal and symptomatic Lewy body diseases | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,637,479 | August 1, 2023 | July 31, 2028 | RYMAN, SEPHIRA | reporter.nih.gov |
| Developing Protein-based MRI Biomarkers for Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2024 | $2,630,332 | September 15, 2020 | May 31, 2026 | ZHOU, JINYUAN | reporter.nih.gov |
| 24-hour Activity Cycles to Optimize Cognitive Resilience to Alzheimer's Disease in African Americans: The Jackson Heart Study | NIH | National Institute on Aging | 2021 to 2023 | $2,629,362 | September 15, 2020 | May 31, 2026 | GABRIEL, KELLEY PETTEE | reporter.nih.gov |
| Development and validation of novel models for cerebral small vessel disease and vascular cognitive impairment | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,624,637 | September 18, 2019 | August 31, 2025 | GOULD, DOUGLAS | reporter.nih.gov |
| Validation of Imaging and Blood-based Small Vessel VCID Biomarkers in Multiethnic Population | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,623,751 | September 30, 2016 | July 31, 2023 | WANG, DANNY JJ | reporter.nih.gov |
| Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,619,994 | September 30, 2016 | July 31, 2023 | LU, HANZHANG | reporter.nih.gov |
| Development of a PIKFYVE Antisense Oligonucleotide Treatment for FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2022 | $2,612,154 | March 1, 2022 | August 31, 2023 | ALWORTH, SAMUEL V | reporter.nih.gov |
| The impact of early Tau pathology on cognitive progression and neuropsychiatric symptoms in Parkinson's disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,609,788 | September 20, 2019 | August 31, 2025 | POSTON, KATHLEEN LOMBARD | reporter.nih.gov |
| Diversity Supplement for Jenny Lutshumba | NIH | National Institute on Aging | 2023 to 2024 | $2,600,455 | September 1, 2023 | August 31, 2026 | STOWE, ANN MARIE | reporter.nih.gov |
| Slow wave sleep (SWS) and the effect of African ancestry on amyloid burden, a longitudinal study | NIH | National Institute on Aging | 2021 to 2022 | $2,599,842 | September 1, 2018 | May 31, 2025 | OSORIO, RICARDO S | reporter.nih.gov |
| Cerebral Microvascular Signaling and Neurovascular Coupling: An Integrated Approach to Investigate VCID | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,597,866 | August 1, 2021 | June 30, 2026 | TSOUKIAS, NIKOLAOS MICHAEL | reporter.nih.gov |
| Sex differences in the contribution of cerebrovascular injury and immune activation to neurocognitive impairment in HIV infection | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,594,711 | May 15, 2022 | February 28, 2027 | CHOW, FELICIA C. | reporter.nih.gov |
| Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study | NIH | National Institute on Aging | 2021 to 2024 | $2,594,669 | April 15, 2020 | March 31, 2026 | MURABITO, JOANNE M | reporter.nih.gov |
| Human 3D Neuro-Vascular Interaction and Meningeal Lymphatic Models with Application to Alzheimer’s Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,593,927 | May 1, 2021 | April 30, 2026 | KAMM, ROGER D | reporter.nih.gov |
| Blood-Brain Barrier Disruption as a Biomarker for Perioperative Neurocognitive Disorder:Cognitive Recovery after Elective Surgery | NIH | National Institute on Aging | 2021 to 2024 | $2,592,630 | May 1, 2019 | February 28, 2026 | DAIELLO, LORI A | reporter.nih.gov |
| Veri-T: A phase 1 Placebo-Controlled Trial of Verdiperstat in Semantic Variant Primary Progressive Aphasia Due to Underlying FTLD-TDP | NIH | National Institute on Aging | 2021 to 2024 | $2,589,914 | August 1, 2021 | July 31, 2026 | LJUBENKOV, PETER ALEXANDER | reporter.nih.gov |
| Using AI on Routine Clinical and Imaging Data from Acute Stroke Encounter to Predict Post-Stroke Vascular Contributions to Cognitive Impairment (AI - RESPECT) | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $2,575,013 | September 1, 2024 | July 31, 2027 | HU, XIAO | reporter.nih.gov |
| Interpretable Deep Learning Methods to Investigate Genetics and Epigenetics of Alzheimer's Disease at a Single-Cell Resolution | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,574,000 | August 30, 2022 | July 31, 2027 | ZHANG, JING | reporter.nih.gov |
| Investigating the Role and the therapeutic potential of Perlecan in experimental vascular dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,573,724 | June 12, 2024 | April 30, 2027 | BIX, GREGORY JAYE | reporter.nih.gov |
| Neural circuit basis for neurovascular coupling | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,572,256 | February 15, 2021 | January 30, 2027 | ROSS, SARAH ELIZABETH | reporter.nih.gov |
| Transferring Speed of Processing Gains to Everyday Cognitive Tasks after Stroke | NIH | National Institute on Aging | 2021 to 2024 | $2,570,286 | September 5, 2021 | August 31, 2025 | USWATTE, GITENDRA | reporter.nih.gov |
| Pericyte control of capillary perfusion in the Alzheimer's disease brain | NIH | National Institute on Aging | 2023 to 2025 | $2,557,000 | April 15, 2023 | January 31, 2028 | SHIH, ANDY Y | reporter.nih.gov |
| Neuropathology and inflammation in a nonhuman primate model of insulin resistance/metabolic syndrome | NIH | National Institute on Aging | 2024 to 2025 | $2,556,565 | February 15, 2024 | November 30, 2028 | HAVEL, PETER J | reporter.nih.gov |
| Biomarker discovery for parkinsonian diseases in extracellular vesicles from iPSC-derived neurons | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $2,555,369 | April 1, 2023 | March 31, 2026 | BITAN, GAL | reporter.nih.gov |
| Neurostimulation of the Nucleus Basalis of Meynert for the cognitive-motor syndrome in Parkinson's disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $2,549,857 | August 19, 2022 | July 31, 2027 | BRONTE-STEWART, HELEN | reporter.nih.gov |
| Impact of SARS-CoV-2 on the cerebrovasculature as a risk factor for VCID: Role of Wnt/beta-catenin | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,549,080 | August 11, 2025 | July 31, 2029 | LUTZ, SARAH ELIZABETH | reporter.nih.gov |
| Novel Imaging and Biofluid Biomarkers of Small Vessel Cerebrovascular Disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,547,585 | September 30, 2016 | July 31, 2023 | KRAMER, JOEL H | reporter.nih.gov |
| Origins, properties, and therapeutic potential of cells that repopulate the microglia-depleted adult brain | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,547,120 | February 15, 2014 | August 31, 2029 | GREEN, KIM | reporter.nih.gov |
| A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration Syndromes | NIH | National Institute on Aging | 2022 to 2024 | $2,546,364 | September 30, 2022 | August 31, 2025 | VAZIRI, ASHKAN | reporter.nih.gov |
| Citalopram as a posterior cortical protective therapy in Parkinson disease | NIH | National Institute on Aging | 2021 to 2024 | $2,545,093 | August 15, 2020 | April 30, 2026 | KOTAGAL, VIKAS | reporter.nih.gov |
| Investigating Pathogenic Mechanisms of Frontotemporal Dementia Caused by Mutations in CHMP2B and TBK1 | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,537,267 | January 1, 2018 | November 30, 2025 | GAO, FEN-BIAO | reporter.nih.gov |
| Non-Invasive Imaging Markers to Elicit the Role of Vascular Involvement in Alzheimer’s Disease | NIH | National Institute on Aging | 2022 to 2025 | $2,534,541 | February 15, 2022 | January 31, 2027 | JOHNSON, KEVIN MICHAEL | reporter.nih.gov |
| The role of brain border-associated macrophages in aging and cerebral amyloid angiopathy | NIH | National Institute on Aging | 2022 to 2025 | $2,534,516 | January 15, 2022 | December 31, 2026 | LAFAILLE, JUAN | reporter.nih.gov |
| BRAIN HEALTH TOGETHER: A LIVE-STREAMING GROUP-BASED DIGITAL PROGRAM | NIH | National Institute on Aging | 2021 to 2023 | $2,534,108 | September 30, 2021 | November 30, 2024 | BENJAMIN, CYNTHIA LOUISE | reporter.nih.gov |
| Effects of NAD restoration on neurovascular coupling in community dwelling older adults | NIH | National Institute on Aging | 2022 to 2025 | $2,531,921 | August 15, 2022 | April 30, 2027 | YABLUCHANSKIY, ANDRIY | reporter.nih.gov |
| Activated protein C mechanisms of brain white matter protection and new therapies for brain white matter ischemic injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,531,008 | July 15, 2020 | April 30, 2026 | MACK, WILLIAM J | reporter.nih.gov |
| Vascular Contributions to Cognitive Impairment after Adverse Pregnancy Outcomes: the nuMoM2b-Heart Health Study | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,523,397 | July 15, 2021 | June 30, 2027 | MILLER, ELIZA C | reporter.nih.gov |
| Sex-specific cognitive expression and risk in preclinical Alzheimer's disease | NIH | National Institute on Aging | 2021 to 2023 | $2,519,693 | September 15, 2019 | May 31, 2025 | BANKS, SARAH | reporter.nih.gov |
| Toward Personalized Prognosis and Outcomes in Primary Progressive Aphasia | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,515,977 | April 17, 2023 | March 31, 2026 | DICKERSON, BRADFORD C | reporter.nih.gov |
| STAT3 activation in astrocytes as a driver of neurovascular dysfunction in Alzheimer's disease and related dementias | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $2,515,763 | September 19, 2022 | August 31, 2025 | LIPPMANN, ETHAN | reporter.nih.gov |
| The Contribution of Repetitive Head Impacts and Social Determinants of Health to Alzheimer's Disease and Related Dementia in Older Adult Black Men | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2024 | $2,514,590 | August 15, 2023 | July 31, 2028 | TURNER, ROBERT W. | reporter.nih.gov |
| Effects of global brain health on sensorimotor recovery after stroke | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,507,791 | April 1, 2020 | March 31, 2026 | LIEW, SOOK-LEI | reporter.nih.gov |
| In vivo modelling and therapy development for stathmin-2 loss in TDP-43 proteinopathies | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,507,311 | August 1, 2021 | July 31, 2024 | LAGIER-TOURENNE, CLOTILDE | reporter.nih.gov |
| Molecular probes to image and target the neurovascular unit in health and disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,505,709 | December 1, 2019 | November 30, 2025 | GRUTZENDLER, JAIME | reporter.nih.gov |
| Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older Adults | NIH | National Institute on Aging | 2022 to 2025 | $2,505,518 | September 30, 2022 | June 30, 2027 | GRODSTEIN, FRANCINE | reporter.nih.gov |
| Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,499,958 | April 1, 2022 | August 31, 2027 | LEIGH, RICHARD | reporter.nih.gov |
| Novel Approaches for Tau PROTAC Drug Discovery | NIH | National Institute on Aging | 2023 to 2024 | $2,499,622 | September 15, 2020 | March 31, 2026 | BUTT, TAUSEEF R. | reporter.nih.gov |
| Investigating physiologic and pathophysiologic connections between the Parkinson's disease protein alpha-synuclein and RNA binding proteins | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,493,768 | August 1, 2023 | July 31, 2028 | KHURANA, VIKRAM | reporter.nih.gov |
| Microglial regulation of Progranulin levels | NIH | National Institute on Aging | 2021 to 2024 | $2,492,948 | February 1, 2020 | December 31, 2025 | LIM, JANGHOO | reporter.nih.gov |
| Early Detection of Mild Cognitive Impairment, Alzheimer's Disease and Other Dementias using EHR | NIH | National Institute on Aging | 2021 to 2025 | $2,490,121 | September 15, 2020 | May 31, 2027 | SOHN, SUNGHWAN | reporter.nih.gov |
| Imaging Cerebral Small Vessels in Vascular Cognitive Impairment and Dementia (VCID) | NIH | National Institute on Aging | 2023 | $2,487,668 | September 1, 2023 | August 31, 2026 | WANG, DANNY JJ | reporter.nih.gov |
| Robust detection of atrophy over short intervals in AD and FTLD | NIH | National Institute on Aging | 2023 to 2025 | $2,487,385 | May 15, 2023 | March 31, 2028 | DICKERSON, BRADFORD C | reporter.nih.gov |
| Function of TMEM106B in Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,485,615 | April 1, 2021 | March 31, 2027 | HU, FENGHUA | reporter.nih.gov |
| Gene therapy for disorders of the extracellular matrix | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,481,348 | April 1, 2023 | March 31, 2026 | GOULD, DOUGLAS | reporter.nih.gov |
| Bidirectional Brain-Gut interactions, chronic neuroinflammation and neurodegeneration after traumatic brain injury | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,480,051 | August 15, 2022 | July 31, 2027 | FADEN, ALAN IRA | reporter.nih.gov |
| Chemical approaches to selectively target beta-rich amyloids | NIH | National Institute on Aging | 2021 to 2025 | $2,477,656 | August 15, 2021 | May 31, 2026 | DEL VALLE, JUAN R | reporter.nih.gov |
| The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,474,168 | August 1, 2015 | April 30, 2027 | MAZZULLI, JOSEPH R | reporter.nih.gov |
| Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementia | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,472,997 | September 1, 2016 | July 31, 2023 | ARFANAKIS, KONSTANTINOS | reporter.nih.gov |
| Closing the gap between structural biology and translational science for amyloid diseases | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,469,735 | September 1, 2021 | August 31, 2026 | SAELICES GOMEZ, LORENA | reporter.nih.gov |
| Molecular Basis of Pathogenic Cascades in ALS/FTD Initiated from C9orf72 Hexanucleotide Repeat Expansion | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,469,291 | July 15, 2022 | May 31, 2027 | WANG, JIOU | reporter.nih.gov |
| Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE) | NIH | National Institute on Aging | 2021 to 2025 | $2,465,845 | February 15, 2019 | November 30, 2025 | NEWTON, ROBERT LEE | reporter.nih.gov |
| Imaging epigenetic dysregulation in the Lewy body dementias with [11C]Martinostat | NIH | National Institute on Aging | 2023 to 2025 | $2,463,125 | May 1, 2023 | March 31, 2028 | GOMPERTS, STEPHEN N. | reporter.nih.gov |
| Leveraging Electronic Health Records and artificial IntelligeNce to improve Dementia Screening and early Detection in primary care (LEARN-DSD) | NIH | National Institute on Aging | 2023 to 2025 | $2,462,815 | September 21, 2023 | July 31, 2028 | RAZAVIAN, NARGES | reporter.nih.gov |
| Brain lymphatic activation for craniosynostosis and Alzheimer’s disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,461,369 | June 1, 2024 | May 31, 2027 | CHEN, JIANFU | reporter.nih.gov |
| Disruption of Nucleocytoplasmic Transport in FUS-related Neurodegenerative Diseases | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,460,641 | May 15, 2019 | September 30, 2024 | BOSCO, DARYL ANGELA | reporter.nih.gov |
| Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | NIH | National Institute on Aging | 2022 | $2,459,487 | May 15, 2022 | April 30, 2025 | SHIH, ANDY Y | reporter.nih.gov |
| Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging - AD/ADRD | NIH | National Institute on Aging | 2021 to 2023 | $2,458,774 | April 1, 2019 | January 31, 2025 | KACENA, MELISSA A | reporter.nih.gov |
| Dysregulation of autophagy-lysosomal function links TBI to late-onset neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,458,515 | April 1, 2020 | March 31, 2026 | LIPINSKI, MARTA M | reporter.nih.gov |
| Early Detection and Treatment of Emerging Cognitive-Linguistic Impairment in Minority Cognitive Aging and Primary Progressive Aphasia | NIH | National Institute on Deafness and Other Communication Disorders | 2021 to 2025 | $2,454,933 | February 1, 2014 | January 31, 2029 | REILLY, JAMES JOSEPH | reporter.nih.gov |
| Velocity-Selective Arterial Spin Labeling based Perfusion Mapping for Alzheimer's disease | NIH | National Institute on Aging | 2023 | $2,448,470 | May 1, 2023 | April 30, 2026 | QIN, QIN | reporter.nih.gov |
| RNA-based regulation of TDP-43 nuclear export in ALS/FTD | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,447,618 | August 1, 2021 | June 30, 2026 | HOKE, AHMET | reporter.nih.gov |
| Role of central and peripheral immune crosstalk in FTD-Grn neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,446,942 | August 17, 2022 | July 30, 2025 | TANSEY, MARIA DE LOURDES GAMEZ | reporter.nih.gov |
| Mechanisms of Prion Aggregation | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,445,436 | March 15, 2011 | April 30, 2027 | SIGURDSON, CHRISTINA | reporter.nih.gov |
| Vascular contributions to HIV-associated Neurocognitive Disorders (HAND) | NIH | National Institute on Aging | 2022 to 2024 | $2,441,402 | August 1, 2022 | July 31, 2027 | GUTIERREZ, JOSE | reporter.nih.gov |
| Development of perivascular space mapping toolset as a diagnostic aid for Alzheimer's disease | NIH | National Institute on Aging | 2024 to 2025 | $2,439,170 | August 1, 2024 | July 31, 2027 | CHOUPAN, JEIRAN | reporter.nih.gov |
| Cell-Type Specific Vulnerability to Tauopathy and Its Prevention in Multiple Models | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,438,130 | February 1, 2021 | January 31, 2024 | SIGURDSSON, EINAR M | reporter.nih.gov |
| Alzheimer's tauopathy phenotype and the microRNA22-3p: implication for pathogenesis | NIH | National Institute on Aging | 2021 to 2025 | $2,431,481 | September 1, 2021 | June 30, 2027 | PRATICO, DOMENICO | reporter.nih.gov |
| The Contribution of Age-Related Tauopathies to Alzheimer's Disease | NIH | National Institute on Aging | 2023 | $2,430,703 | September 30, 2018 | August 31, 2026 | MCKEE, ANN C. | reporter.nih.gov |
| Role of Microglia in Cerebral Small Vessel Disease (CSVD)/Vascular Cognitive Impairment (VCI) | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,430,570 | July 15, 2022 | June 30, 2027 | WEINSTEIN, JONATHAN R | reporter.nih.gov |
| Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation | NIH | National Institute on Aging | 2021 to 2023 | $2,427,515 | August 1, 2019 | April 30, 2026 | BOWERS, DAWN | reporter.nih.gov |
| Biochemical and molecular heterogeneity of human TDP-43 proteinopathies in age-related dementias | NIH | National Institute on Aging | 2022 to 2025 | $2,424,308 | July 15, 2022 | April 30, 2027 | PORTA ANTOLINEZ, SILVIA | reporter.nih.gov |
| MESA-CEND: Promoting diversity in Alzheimer’s disease research | NIH | National Institute on Aging | 2021 to 2022 | $2,424,017 | August 15, 2021 | July 31, 2024 | DEEP, GAGAN | reporter.nih.gov |
| Lysosomal Function of Progranulin and Neurodegeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,421,653 | August 1, 2017 | February 28, 2027 | HU, FENGHUA | reporter.nih.gov |
| Inspiring Healthy Engagement and Learning for Vascular Dementia (I-HEAL) | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,421,629 | September 1, 2025 | August 31, 2029 | CABAN-HOLT, ALLISON MERCEDES | reporter.nih.gov |
| Human cerebral blood flow regulation: sex, mechanism, and stress differences | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,414,516 | June 1, 2020 | May 31, 2025 | SCHRAGE, WILLIAM G | reporter.nih.gov |
| Multiethnic Validation of VCID biomarkers in South Texas | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,412,788 | September 30, 2021 | July 31, 2023 | SATIZABAL, CLAUDIA L | reporter.nih.gov |
| Innovating high-resolution novel imaging approaches to elucidate mechanisms of prion-like spreadingof neurodegenerative disease | NIH | National Institute on Aging | 2021 to 2024 | $2,409,422 | May 1, 2020 | February 28, 2026 | LEE, JIN HYUNG | reporter.nih.gov |
| A Diagnostic Test for Dementia with Lewy Bodies | NIH | National Institute on Aging | 2022 to 2023 | $2,408,271 | April 1, 2022 | March 31, 2026 | LEVINE, TODD | reporter.nih.gov |
| Vascular Contributors to Blood Brain Barrier Permeability and Regional White Matter Hyperintensity Progression in Young Asymptomatic People | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,407,043 | July 15, 2022 | April 30, 2025 | NYQUIST, PAUL ALAN | reporter.nih.gov |
| REACH-EpiVCID | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,403,545 | August 5, 2024 | July 31, 2027 | ANDERSON, CHRISTOPHER DAVID | reporter.nih.gov |
| Mechanisms of APOE-Induced Preclinical Alzheimer's Pathophysiology in Human Olfactory System | NIH | National Institute on Aging | 2021 to 2023 | $2,398,805 | August 15, 2019 | May 31, 2025 | NWULIA, EVARISTUS A | reporter.nih.gov |
| Brain capillary endothelial cell energetics and neurovascular uncoupling in dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,398,590 | September 24, 2024 | August 31, 2026 | DABERTRAND, FABRICE | reporter.nih.gov |
| TMEM106B in neurodegenerative disease | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,390,842 | July 15, 2013 | February 28, 2025 | CHEN-PLOTKIN, ALICE S | reporter.nih.gov |
| Interaction between microvascular function and CSF clearance in Lewy body dementia | NIH | National Institute on Aging | 2023 | $2,387,139 | June 1, 2023 | May 31, 2026 | HUA, JUN | reporter.nih.gov |
| Dissecting the Etiology of The Lewy Body Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,383,188 | May 1, 2022 | April 30, 2025 | FINKBEINER, STEVEN M | reporter.nih.gov |
| Reward processing in genetic frontotemporal dementia and mood disorders | NIH | National Institute on Aging | 2021 to 2023 | $2,382,005 | March 1, 2019 | December 31, 2025 | PERRY, DAVID C | reporter.nih.gov |
| Role of TREX1 in age-related hereditary leukoencephalopathy | NIH | National Institute of Neurological Disorders and Stroke | 2023 to 2025 | $2,381,292 | September 20, 2023 | June 30, 2028 | MINER, JONATHAN J | reporter.nih.gov |
| Type 2 Diabetes Mellitus and Vascular Contributions to Cognitive Impairment and Dementia (T2DM-VCID) | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,380,018 | September 18, 2024 | August 31, 2027 | LEVINE, DEBORAH ALLISON | reporter.nih.gov |
| Mechanisms of Vasomotion-mediated Perivascular Clearance in Cerebral Amyloid Angiopathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2025 | $2,376,712 | August 1, 2022 | July 31, 2027 | GREENBERG, STEVEN M | reporter.nih.gov |
| Alzheimer Pathology and Neurovascular Dysfunction | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,375,220 | July 1, 1998 | December 31, 2027 | IADECOLA, COSTANTINO | reporter.nih.gov |
| Genetic and Environmental Risk Factors for Hemorrhagic Stroke – V | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,374,719 | September 12, 1997 | July 31, 2027 | WOO, DANIEL | reporter.nih.gov |
| Investigating the role of Alpha5Beta1 integrin in cognitive dysfunction | NIH | National Institute on Aging | 2023 to 2024 | $2,373,215 | April 1, 2023 | March 31, 2026 | BIX, GREGORY JAYE | reporter.nih.gov |
| Dynamic Brain Imaging of Speech in Primary Progressive Aphasia | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,373,138 | September 15, 2017 | June 30, 2026 | NAGARAJAN, SRIKANTAN S. | reporter.nih.gov |
| Validating remote digital assessments for familial frontotemporal dementia | NIH | National Institute on Aging | 2022 | $2,371,437 | May 1, 2022 | April 30, 2025 | STAFFARONI, ADAM MARK | reporter.nih.gov |
| Identifying A Skeleton-Derived Factor for Vascular Aging | NIH | National Institute on Aging | 2021 to 2025 | $2,368,758 | April 1, 2021 | December 31, 2026 | WAN, MEI | reporter.nih.gov |
| Blood-brain barrier dysfunction in Alzheimer's disease: from humans to animal models | NIH | National Institute on Aging | 2021 | $2,368,153 | May 1, 2021 | April 30, 2024 | LU, HANZHANG | reporter.nih.gov |
| C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approaches | NIH | National Institute on Aging | 2021 to 2022 | $2,365,559 | May 1, 2021 | April 30, 2024 | CONKLIN, BRUCE R | reporter.nih.gov |
| Synaptopathy and Pathogenesis in Frontotemporal Dementia: Role of CYLD | NIH | National Institute on Aging | 2023 | $2,364,013 | June 1, 2023 | May 31, 2026 | YAO, WEI-DONG | reporter.nih.gov |
| "What is N?" Towards operationalizing neurodegeneration in Alzheimer's and related dementias | NIH | National Institute on Aging | 2021 | $2,360,353 | April 15, 2021 | March 31, 2024 | GRAFF-RADFORD, JONATHAN | reporter.nih.gov |
| Epigenetic Aging Cognitive Function and Exercise in Older Adults | NIH | National Institute on Aging | 2024 | $2,358,537 | September 1, 2024 | August 31, 2027 | CONLEY, YVETTE P | reporter.nih.gov |
| Loss of VCP Function in Frontotemporal Lobar Degeneration | NIH | National Institute on Aging | 2022 | $2,356,099 | June 1, 2022 | May 31, 2025 | LEE, EDWARD BYUNG-HA | reporter.nih.gov |
| SPAK-NKCC1 complex and the blood-CSF barrier dysregulation in VCID | NIH | National Institute of Neurological Disorders and Stroke | 2025 | $2,353,206 | September 8, 2025 | June 30, 2029 | SUN, DANDAN | reporter.nih.gov |
| Vascular Mechanisms of Dementia: Cell-Type Specific Therapeutic and Imaging Strategies | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,352,735 | July 1, 2022 | June 30, 2025 | GRUTZENDLER, JAIME | reporter.nih.gov |
| C9orf72-mediated features, transcriptomic signatures, and translational studies for frontotemporal dementia and related disorders | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,351,241 | June 15, 2022 | May 31, 2025 | VAN BLITTERSWIJK, MARKA | reporter.nih.gov |
| CSF Clearance in Sporadic Alzheimer's Disease | NIH | National Institute on Aging | 2021 to 2023 | $2,348,572 | August 15, 2019 | April 30, 2025 | LI, YI | reporter.nih.gov |
| Imaging of cerebral microvascular pulsatility in cerebral small vessel disease | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,346,270 | August 1, 2024 | June 30, 2027 | YAN, LIRONG | reporter.nih.gov |
| Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,345,590 | July 15, 2021 | June 30, 2027 | ZHANG, YONGJIE | reporter.nih.gov |
| Adverse Cerebrovascular Responses to Antibodies Targeting Beta-Amyloid | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,342,415 | June 1, 2024 | May 31, 2027 | CRIBBS, DAVID HASTINGS | reporter.nih.gov |
| The Impact of Beta- and Gamma-synucleins on Alpha-synuclein's Synaptic Function | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2023 | $2,342,275 | May 1, 2023 | March 31, 2024 | BURRE, JACQUELINE | reporter.nih.gov |
| COVID-19-related blood-brain barrier and microstructural brain injury; Sex differences and synergy with Alzheimer's disease risk | NIH | National Institute on Aging | 2023 to 2025 | $2,337,162 | December 15, 2022 | November 30, 2027 | REAS, EMILIE T. | reporter.nih.gov |
| Neuroplasticity and the emergence of motor and cognitive deficits in prodromal synucleinopathy | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,336,166 | August 15, 2022 | July 31, 2025 | MACKINNON, COLUM D | reporter.nih.gov |
| Blinded Comparison of Different Alpha-Synuclein Seeding Assays as Cutaneous Biomarkers of Lewy Body Dementias | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2024 | $2,335,086 | September 15, 2021 | August 31, 2025 | BEACH, THOMAS G | reporter.nih.gov |
| Investigations of Dementia in Parkinson Disease | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,332,494 | September 23, 2021 | August 31, 2026 | PERLMUTTER, JOEL SYNES | reporter.nih.gov |
| Common mechanistic biomarkers of vascular and neuro-degeneration | NIH | National Institute on Aging | 2023 to 2025 | $2,330,263 | January 1, 2023 | December 31, 2027 | LIU, YONGMEI | reporter.nih.gov |
| Tau Conformation in Tauopathies and Neuronal Function | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,326,506 | April 15, 2014 | April 30, 2025 | BRADY, SCOTT THOMAS | reporter.nih.gov |
| Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosis | NIH | National Institute on Aging | 2021 | $2,326,501 | April 1, 2021 | March 31, 2024 | VIDAL, RUBEN | reporter.nih.gov |
| Overlapping Molecular Dysregulation of Endolysosomal Function in Alzheimer's Disease and FTLD-TDP | NIH | National Institute on Aging | 2021 to 2023 | $2,325,777 | September 15, 2019 | May 31, 2025 | STRITTMATTER, STEPHEN M | reporter.nih.gov |
| Building a Platform for Precision Anesthesia for the Geriatric Surgical Patient | NIH | National Institute on Aging | 2022 to 2024 | $2,319,904 | September 1, 2020 | August 31, 2025 | DROVER, DAVID RAYMOND | reporter.nih.gov |
| Map Paravascular Fluid Dynamic Signatures of Key Aging and AD Processes Using Dynamics Diffusion-Weighted Imaging | NIH | National Institute on Aging | 2023 | $2,317,887 | September 15, 2023 | August 31, 2026 | WEN, QIUTING | reporter.nih.gov |
| Protein Aggregation and Neurotransmitter Deficits in Parkinson Disease | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,315,618 | August 1, 2016 | June 30, 2027 | KOTZBAUER, PAUL T | reporter.nih.gov |
| Contributions of tau-mediated translational dysregulation to pathogenesis and progression of fronto-temporal dementia | NIH | National Institute on Aging | 2022 to 2025 | $2,310,587 | February 1, 2022 | January 31, 2027 | ABISAMBRA, JOSE FRANCISCO | reporter.nih.gov |
| Pulsed laser therapy in an asymptomatic head injury-accelerated Alzheimer's model | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,309,898 | September 17, 2024 | August 31, 2027 | ZHANG, QUANGUANG | reporter.nih.gov |
| Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,309,451 | September 15, 2021 | August 31, 2024 | ALOSCO, MICHAEL | reporter.nih.gov |
| Leveraging a Natural Experiment to Determine the Effects of Integrated Palliative Care on Health Service Outcomes and Disparities in Parkinson Disease and Lewy Body Dementia | NIH | National Institute of Neurological Disorders and Stroke | 2023 | $2,307,536 | August 21, 2023 | July 31, 2026 | WILLIS, ALLISON | reporter.nih.gov |
| Role of Cholecystokinin in the Dentate Gyrus | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2025 | $2,307,005 | June 1, 2021 | March 31, 2027 | SONG, JUAN | reporter.nih.gov |
| CAPSTONE: Central And Peripheral STrOke inflammatioN with Exosomes | NIH | National Institute of Neurological Disorders and Stroke | 2022 to 2024 | $2,297,999 | July 19, 2022 | June 30, 2027 | WALSH, KYLE BRENDAN | reporter.nih.gov |
| High-speed imaging of cortical and white matter microvascular flow in AD/ADRD models | NIH | National Institute of Neurological Disorders and Stroke | 2022 | $2,296,464 | August 15, 2022 | July 31, 2025 | SCHAFFER, CHRIS B | reporter.nih.gov |
| Determine the role of atmospheric particulate matter pollutants in contributing to Lewy Body Dementia | NIH | National Institute on Aging | 2023 | $2,296,059 | April 15, 2023 | March 31, 2026 | MAO, XIAOBO | reporter.nih.gov |
| White Matter Metabolism in the Context of Aging, White Matter Hyperintensities and Alzheimer's Disease | NIH | National Institute on Aging | 2022 | $2,287,856 | May 1, 2022 | April 30, 2025 | VLASSENKO, ANDREI G. | reporter.nih.gov |
| TBI-ADRD Modeling with a Team Science Approach (TBI-ADRD Team Science) | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,283,334 | September 18, 2024 | August 31, 2027 | WANG, KEVIN KA WANG | reporter.nih.gov |
| Microscopic and Large-Scale Networks of Molecular Pathology in Frontotemporal Lobar Degeneration | NIH | National Institute of Neurological Disorders and Stroke | 2021 to 2023 | $2,282,984 | August 1, 2019 | June 30, 2025 | IRWIN, DAVID JOHN | reporter.nih.gov |
| Investigating and targeting apolipoprotein E4 in Down syndrome-associated Alzheimer's disease | NIH | National Institute on Aging | 2023 | $2,282,487 | July 15, 2023 | June 30, 2026 | JOHNSON, NOAH RAY | reporter.nih.gov |
| Full human gene-replacement mouse models of ADRDs | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $2,280,898 | September 18, 2019 | August 31, 2025 | KOOB, MICHAEL D | reporter.nih.gov |
| Novel fibril-selective nanobody-based agents targeting intracellular and extracellular α-synuclein aggregates and prion-like propagation induced dementia | NIH | National Institute of Neurological Disorders and Stroke | 2024 | $2,280,379 | September 19, 2024 | August 31, 2027 | WANG, WENJING | reporter.nih.gov |
| The effect of circadian rhythm disruptions on the angiogenic response to hypoperfusion in the AD brain | NIH | National Institute on Aging | 2023 to 2025 | $2,278,875 | May 1, 2023 | January 31, 2028 | ARAI, KEN | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| Columbia University Health Sciences | New York, NY | 49 | $226.1 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 87 | $179.4 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 84 | $163.7 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 28 | $153.7 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 25 | $125.6 million | 0 | $0 |
| University of Pennsylvania | Philadelphia, PA | 63 | $124.4 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 70 | $119 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 56 | $100.8 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 41 | $83.9 million | 0 | $0 |
| University of Southern California | Los Angeles, CA | 34 | $78.9 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 42 | $75.2 million | 0 | $0 |
| University of California at Davis | Davis, CA | 16 | $65.5 million | 0 | $0 |
| Rush University Medical Center | Chicago, IL | 21 | $64.9 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 16 | $61.9 million | 0 | $0 |
| University of Florida | Gainesville, FL | 43 | $61.8 million | 0 | $0 |
| Washington University | Saint Louis, MO | 42 | $61.1 million | 0 | $0 |
| New York University School of Medicine | New York, NY | 21 | $58 million | 0 | $0 |
| Wake Forest University Health Sciences | Winston-Salem, NC | 14 | $53.3 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 29 | $52.3 million | 0 | $0 |
| University of Miami School of Medicine | Coral Gables, FL | 19 | $50 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 32 | $49.4 million | 0 | $0 |
| Mayo Clinic Jacksonville | Jacksonville, FL | 23 | $48.6 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 24 | $46.1 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 26 | $45.9 million | 0 | $0 |
| University of South Florida | Tampa, FL | 12 | $44.7 million | 0 | $0 |
| Emory University | Atlanta, GA | 24 | $42 million | 0 | $0 |
| University of Texas HLTH Science Center | San Antonio, TX | 15 | $40.1 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 28 | $39.8 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 20 | $39.1 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 30 | $38 million | 0 | $0 |
| Stanford University | Stanford, CA | 23 | $37.7 million | 0 | $0 |
| Tulane University of Louisiana | New Orleans, LA | 13 | $36.6 million | 0 | $0 |
| Yale University | New Haven, CT | 29 | $35.9 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 23 | $34.1 million | 0 | $0 |
| Ut Southwestern Medical Center | Dallas, TX | 15 | $30.6 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 15 | $29.8 million | 0 | $0 |
| Cognition Therapeutics, Inc. | Pittsburgh, PA | 1 | $29.5 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 21 | $27.5 million | 0 | $0 |
| University of California-Berkeley | Berkeley, CA | 6 | $27.3 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 25 | $26.8 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 14 | $26.6 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 10 | $26.1 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 19 | $26 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 20 | $25.7 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 23 | $24.6 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 16 | $24.1 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 9 | $23.8 million | 0 | $0 |
| Albert Einstein College of Medicine | Bronx, NY | 8 | $23.3 million | 0 | $0 |
| Duke University | Durham, NC | 13 | $22.9 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 20 | $22.8 million | 0 | $0 |
| University of Vermont & ST Agric College | Burlington, VT | 10 | $21.6 million | 0 | $0 |
| Eip Pharma, Inc. | Boston, MA | 1 | $21.1 million | 0 | $0 |
| J. David Gladstone Institutes | San Francisco, CA | 9 | $18.3 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 14 | $17.6 million | 0 | $0 |
| Massachusetts Institute of Technology | Cambridge, MA | 9 | $17.6 million | 0 | $0 |
| University of Washington | Seattle, WA | 15 | $17.2 million | 0 | $0 |
| Vanderbilt University | Nashville, TN | 16 | $17 million | 0 | $0 |
| SUNY at Stony Brook | Stony Brook, NY | 10 | $16.8 million | 0 | $0 |
| University of Rochester | Rochester, NY | 15 | $16.7 million | 0 | $0 |
| Seattle Inst for Biomedical/clinical Res | Seattle, WA | 11 | $16.5 million | 0 | $0 |
| Cornell University | Ithaca, NY | 8 | $16 million | 0 | $0 |
| Regenerative Research Foundation | Albany, NY | 6 | $15.8 million | 0 | $0 |
| Augusta University | Augusta, GA | 13 | $15.6 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 13 | $15.6 million | 0 | $0 |
| Brown University | Providence, RI | 10 | $14.8 million | 0 | $0 |
| SUNY Downstate Medical Center | Brooklyn, NY | 1 | $14.1 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 14 | $13.7 million | 0 | $0 |
| University of New Mexico Health Scis CTR | Albuquerque, NM | 4 | $12.9 million | 0 | $0 |
| Chapman University | Orange, CA | 1 | $12.7 million | 0 | $0 |
| University of Texas at Austin | Austin, TX | 9 | $12.3 million | 0 | $0 |
| Temple Univ of the Commonwealth | Philadelphia, PA | 8 | $11.6 million | 0 | $0 |
| University of Oklahoma HLTH Sciences CTR | Oklahoma City, OK | 12 | $11.4 million | 0 | $0 |
| Rutgers Biomedical and Health Sciences | Newark, NJ | 7 | $11.1 million | 0 | $0 |
| University of Texas Med BR Galveston | Galveston, TX | 5 | $10.9 million | 0 | $0 |
| University of Iowa | Iowa City, IA | 10 | $10.4 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 7 | $10.2 million | 0 | $0 |
| Medical University of South Carolina | Charleston, SC | 8 | $10.1 million | 0 | $0 |
| Board of Regents, NSHE, obo University of Nevada, Reno | Reno, NV | 4 | $9.6 million | 0 | $0 |
| ST. Joseph's Hospital and Medical Center | Phoenix, AZ | 8 | $8.9 million | 0 | $0 |
| Pennsylvania State Univ Hershey Med CTR | Hershey, PA | 5 | $8.8 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 9 | $8.8 million | 0 | $0 |
| University of Chicago | Chicago, IL | 3 | $8.8 million | 0 | $0 |
| Acurastem, Inc. | Pasadena, CA | 4 | $8.7 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 6 | $8.5 million | 0 | $0 |
| Jackson Laboratory | Bar Harbor, ME | 4 | $8.1 million | 0 | $0 |
| Ohio State University | Columbus, OH | 8 | $8.1 million | 0 | $0 |
| Hugo W. Moser Res Inst Kennedy Krieger | Baltimore, MD | 5 | $8.1 million | 0 | $0 |
| Seattle Children's Hospital | Seattle, WA | 6 | $8.1 million | 0 | $0 |
| Pennsylvania State Univ University Park | University Park, PA | 1 | $7.9 million | 0 | $0 |
| Amydis Diagnostics, Inc. | La Jolla, CA | 4 | $7.9 million | 0 | $0 |
| Biosensics, LLC | Newton, MA | 2 | $7.7 million | 0 | $0 |
| Scripps Research Institute, the | La Jolla, CA | 5 | $7.3 million | 0 | $0 |
| Purdue University | West Lafayette, IN | 9 | $7 million | 0 | $0 |
| Thomas Jefferson University | Philadelphia, PA | 12 | $6.8 million | 0 | $0 |
| Upstate Medical University | Syracuse, NY | 7 | $6.5 million | 0 | $0 |
| Washington State University | Pullman, WA | 3 | $6.3 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 6 | $6.3 million | 0 | $0 |
| Rockefeller University | New York, NY | 2 | $6.2 million | 0 | $0 |
| LSU Pennington Biomedical Research CTR | Baton Rouge, LA | 2 | $6.2 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 3 | $6.1 million | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 971 | $909,679,905 | 0 | $0 |
| 2024 | 1,003 | $862,724,404 | 0 | $0 |
| 2023 | 898 | $799,985,633 | 0 | $0 |
| 2022 | 819 | $686,116,518 | 0 | $0 |
| 2021 | 752 | $644,773,937 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.