Data / Research funding / Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome: 624 NIH awards ($679.3M) to 173 organizations
624 NIH awards ($679.3M) in the NIH spending category Acute Respiratory Distress Syndrome, to 173 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.
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Awards
The 500 largest of 624 awards in the window.
| Award | Agency | Institute or division | Fiscal year | Amount in window | Start | End | Principal investigator | Source |
|---|---|---|---|---|---|---|---|---|
| Louisiana Biomedical Research Network | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $18,867,890 | September 25, 2001 | April 30, 2030 | KOUSOULAS, KONSTANTIN G | reporter.nih.gov |
| Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE) | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $16,153,090 | May 1, 2023 | April 30, 2029 | SELF, WESLEY H | reporter.nih.gov |
| 1/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $8,010,367 | September 16, 2020 | August 31, 2025 | BOECKH, MICHAEL J | reporter.nih.gov |
| Optimizing Pain Treatment In Children On Mechanical ventilation (OPTICOM) | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 to 2025 | $6,866,353 | September 5, 2024 | August 31, 2029 | TRAUBE, CHANI | reporter.nih.gov |
| 1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $5,715,477 | September 23, 2019 | August 31, 2025 | LEVITT, JOSEPH ERIC | reporter.nih.gov |
| CCC for NHLBI Prevention and Early Treatment of Acute Lung Injury PETAL Network | NIH | National Heart, Lung, and Blood Institute | 2021 | $5,617,232 | June 17, 2014 | October 31, 2023 | THOMPSON, BOYD TAYLOR | reporter.nih.gov |
| Organizational strategies for improving evidence-uptake in intensive care | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,750,730 | January 21, 2019 | February 28, 2026 | KAHN, JEREMY M | reporter.nih.gov |
| 1/2 PROSpect: Prone and Oscillation Pediatric Clinical Trial (CCC) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $4,351,796 | June 15, 2018 | July 31, 2025 | CURLEY, MARTHA AQ | reporter.nih.gov |
| The Maximizing Extubation outcomes Through Educational and Organizational Research (METEOR) Trial | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $4,315,155 | September 1, 2021 | August 31, 2026 | GIRARD, TIMOTHY D | reporter.nih.gov |
| Investigating Individual Susceptibility and Host Response in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,880,499 | August 19, 2022 | July 31, 2029 | MEYER, NUALA JENNINGS | reporter.nih.gov |
| Precision Medicine in the Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,851,458 | January 16, 2018 | March 31, 2025 | CALFEE, CAROLYN | reporter.nih.gov |
| Cell competition in pulmonary fibrosis and ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,796,920 | August 20, 2022 | July 31, 2029 | DE LANGHE, STIJN PIET JOHAN | reporter.nih.gov |
| Lung Macrophage Programming in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,783,173 | February 15, 2018 | January 31, 2026 | JANSSEN, WILLIAM | reporter.nih.gov |
| Genetic Investigation of Covid 19 in Lung Disease | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,774,284 | August 1, 2022 | July 31, 2027 | KAHN, MARK L | reporter.nih.gov |
| Systematic Investigation of Protein Ubiquitination in ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $3,737,220 | January 26, 2018 | November 30, 2025 | CHEN, BEIBEI | reporter.nih.gov |
| Applying Innovative Lung Mapping Strategies to Understand Alveolar Capillary Barrier Permeability in ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,506,389 | June 1, 2020 | May 31, 2027 | BASTARACHE, JULIE A. | reporter.nih.gov |
| De Novo Design of Minibinder Antagonists for COVID-19 and Future Pandemics | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,504,899 | August 2, 2021 | July 31, 2026 | BAKER, DAVID | reporter.nih.gov |
| Mechanisms of Alveolar Homeostasis, Injury, Regeneration, and Fibrosis | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,471,063 | March 1, 2022 | February 28, 2029 | ZEMANS, RACHEL LYNNE | reporter.nih.gov |
| A Phase III Randomized Controlled Trial of Azithromycin for RSV-induced Respiratory Failure in Children | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2025 | $3,324,945 | August 1, 2021 | July 31, 2027 | KONG, MICHELE | reporter.nih.gov |
| Immunobiology of the normal and injured lung | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,312,758 | January 1, 2022 | December 31, 2028 | LOONEY, MARK ROBERTS | reporter.nih.gov |
| Pathogenesis of lung injury mediated by lung-restricted antibodies | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $3,293,690 | April 1, 2019 | March 31, 2027 | BHARAT, ANKIT | reporter.nih.gov |
| Aspiration in Acute Respiratory Failure Survivors | NIH | National Institute of Nursing Research | 2021 to 2025 | $3,262,196 | August 23, 2021 | May 31, 2027 | MOSS, MARC | reporter.nih.gov |
| A Phase 1b Study of Inhaled CO for the Treatment of Sepsis-Induced ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $3,249,318 | September 15, 2020 | April 30, 2025 | PLATAKI, MARIA | reporter.nih.gov |
| Manufacturable Biomimetic Microfluidic Oxygenator for Safer, Simpler Treatment of Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $3,193,069 | September 17, 2024 | August 31, 2026 | BORENSTEIN, JEFFREY T. | reporter.nih.gov |
| Targeted Gene Delivery Systems Treating Lung Diseases | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,172,072 | June 15, 2022 | May 31, 2026 | TIRRELL, MATTHEW | reporter.nih.gov |
| Mechanism of Immune Dysfunction and Morbid Outcomes in Response to Shock/Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $3,116,857 | May 1, 2016 | October 31, 2026 | AYALA, ALFRED | reporter.nih.gov |
| Mechanisms and pathogenicity of SARS-CoV-2-induced neutrophil extracellular traps | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $3,116,400 | September 17, 2021 | August 31, 2027 | LOONEY, MARK ROBERTS | reporter.nih.gov |
| Animal Models for Studying the Genetics of Complex Diseases | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $3,068,389 | September 30, 1992 | December 31, 2026 | MAEDA, NOBUYO | reporter.nih.gov |
| Genetic Analysis of COVID-19 Susceptibility and Resistance Determinants in the Collaborative Cross | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2024 | $3,064,576 | September 25, 2020 | August 31, 2025 | HEISE, MARK T | reporter.nih.gov |
| CoPARC: Colorado Pulmonary-Alcohol Research Collaborative | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2025 | $3,045,581 | August 1, 2011 | April 30, 2029 | BURNHAM, ELLEN L | reporter.nih.gov |
| 1/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI) | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $3,038,038 | September 1, 2023 | August 31, 2030 | TALMOR, DANIEL STUART | reporter.nih.gov |
| Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated Pneumonia | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $3,027,494 | July 1, 2023 | June 30, 2028 | NIZET, VICTOR | reporter.nih.gov |
| Optimization of orally bioavailable inhibitors for the treatment of COVID-19 and other human coronavirus infections | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $2,999,998 | June 7, 2023 | May 31, 2027 | COBURN, GLEN | reporter.nih.gov |
| Mechanistic role of membrane pore formation in lung-endothelial barrier failure due to blood-borne pathogens. | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,988,753 | June 1, 1985 | July 31, 2027 | BHATTACHARYA, JAHAR | reporter.nih.gov |
| Low Density Neutrophils Link Inflammation and Coagulopathy in COVID-19 | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,948,542 | September 23, 2022 | August 31, 2026 | YAN, JUN | reporter.nih.gov |
| Mechanisms and Treatment of SARS-CoV-2 induced Lung Endothelial Injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,941,237 | February 1, 2022 | January 31, 2027 | REHMAN, JALEES | reporter.nih.gov |
| Defining the Role of Regulatory T Cells in Resolution of Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,933,653 | December 15, 2020 | November 30, 2026 | MOCK, JASON ROBERT | reporter.nih.gov |
| Mechanistic evaluation of the role of circadian rhythms in acute lung injury and subsequent recovery | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,922,801 | September 20, 2021 | August 31, 2027 | SENGUPTA, SHAON | reporter.nih.gov |
| Imaging and Targeting Lung Proteolysis in ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,905,205 | August 26, 2021 | July 31, 2025 | SINUSAS, ALBERT J | reporter.nih.gov |
| Immunogenomic analysis of donor lung injury and its impact on clinical outcomes after lung transplantation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,897,255 | July 10, 2022 | June 30, 2027 | SHAVER, CIARA M | reporter.nih.gov |
| Calpain/talin/MLCP axis in pulmonary endothelial barrier regulation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,873,437 | September 1, 2022 | August 31, 2026 | VERIN, ALEXANDER D | reporter.nih.gov |
| Assessment of Implementation Methods in Sepsis and Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,868,952 | July 15, 2022 | June 30, 2027 | LEVY, MITCHELL M | reporter.nih.gov |
| Predicting and Preventing Ventilator-Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,855,874 | January 1, 2021 | December 31, 2026 | SMITH, BRADFORD J | reporter.nih.gov |
| Targeting Latexin Signaling for Endothelial Barrier Dysfunction in Inflammatory Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,805,290 | August 1, 2021 | July 31, 2025 | SUN, JIANXIN | reporter.nih.gov |
| Impact of particle and ozone inhalation co-exposure on alveolar epithelial regeneration | NIH | National Institute of Environmental Health Sciences | 2021 to 2024 | $2,799,613 | May 1, 2020 | February 28, 2026 | HUSSAIN, SALIK | reporter.nih.gov |
| Dissecting the molecular mechanisms of lung injury during mechanical ventilation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,791,533 | February 15, 2021 | January 31, 2027 | ENGLERT, JOSHUA A | reporter.nih.gov |
| AIBP therapy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,790,000 | February 1, 2017 | January 31, 2024 | MILLER, YURY | reporter.nih.gov |
| Proteolysis in the Pathogenesis of ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,785,315 | December 22, 2021 | November 30, 2025 | DOWNEY, GREGORY PAUL | reporter.nih.gov |
| REGULATION OF THE MACROPHAGE INFLAMMATORY PHENOTYPE IN ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,784,645 | January 1, 2018 | June 30, 2027 | CHRISTMAN, JOHN W | reporter.nih.gov |
| Mechanisms of regulatory T cell-mediated recovery from severe viral pneumonia | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,783,450 | March 1, 2020 | June 30, 2029 | SINGER, BENJAMIN DAVID | reporter.nih.gov |
| Financial Hardship among Patients with Acute Respiratory Failure and their Family Member Caregivers: Understanding the Impact on Patient- and Family- Centered Outcomes | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,771,956 | August 1, 2022 | July 31, 2027 | KHANDELWAL, NITA | reporter.nih.gov |
| An ABO Blood Type Defined ARDS Endotype in Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,726,654 | September 21, 2021 | August 31, 2026 | REILLY, JOHN PATRICK | reporter.nih.gov |
| Controlling complement to unleash nanomedicine for acute critical illnesses | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,697,599 | February 1, 2022 | January 31, 2026 | BRENNER, JACOB | reporter.nih.gov |
| Syndecan-1 suppression of lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,688,430 | April 25, 2022 | March 31, 2026 | CHEN, PETER | reporter.nih.gov |
| Negative regulators of endothelial regeneration in aging lungs and ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,661,375 | June 1, 2022 | March 31, 2026 | ZHAO, YOU-YANG | reporter.nih.gov |
| Lipid and Protein Effects on Monolayer Stability | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,636,289 | July 1, 1994 | June 30, 2029 | ZASADZINSKI, JOSEPH ANTHONY | reporter.nih.gov |
| Preclinical Electron Paramagnetic Resonance Tumor Imager | NIH | National Cancer Institute | 2021 to 2025 | $2,628,042 | July 8, 2021 | June 30, 2027 | EATON, GARETH R | reporter.nih.gov |
| Neuroinflammation Maladapts Cardio Respiratory Circuits and Patterns | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,553,585 | September 1, 2022 | May 31, 2027 | JACONO, FRANK JOSEPH | reporter.nih.gov |
| 2/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI) | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,521,839 | September 1, 2023 | August 31, 2030 | BAEDORF KASSIS, ELIAS | reporter.nih.gov |
| Host Immunity in Sepsis-Induced Systemic Infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2025 | $2,506,165 | May 1, 2021 | April 30, 2027 | JEYASEELAN, SAMITHAMBY | reporter.nih.gov |
| Lung leukocytes promote alveolar epithelial regeneration after severe injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,469,157 | May 1, 2020 | April 30, 2026 | ARPAIA, NICHOLAS | reporter.nih.gov |
| A Randomized Phase 2A Clinical Trial Pioneering the Utility of an eNAMPT-Reducing Therapy in ARDS/VILI: the PUERTA Trial | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $2,457,594 | June 1, 2019 | August 31, 2025 | GARCIA, JOE G. N. | reporter.nih.gov |
| Role and Mitigation of Inflammasomes and Inflammation During COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2025 | $2,428,594 | July 15, 2022 | June 30, 2027 | TING, JENNY P | reporter.nih.gov |
| hHv1 channels in neutrophils and the innate immune inflammatory response | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,426,520 | August 5, 2022 | June 30, 2027 | GOLDSTEIN, STEVE A N | reporter.nih.gov |
| Targeting Estrogenic pathways in Tregs to promote ARDS resolution | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $2,413,250 | June 1, 2022 | May 31, 2026 | D'ALESSIO, FRANCO RAFAEL | reporter.nih.gov |
| Decoding temporal epithelial signaling programs to restore homeostasis in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,400,974 | September 1, 2021 | June 30, 2025 | ALBECK, JOHN G. | reporter.nih.gov |
| Epithelial stem/progenitor cells as repair agents in diffuse alveolar damage | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $2,388,592 | September 21, 2016 | May 31, 2025 | CHAPMAN, HAROLD A | reporter.nih.gov |
| Vascular Targeting Genomic & Genetic Strategies for Acute Chest Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,381,226 | February 5, 2013 | October 31, 2025 | MACHADO, ROBERTO F. | reporter.nih.gov |
| Novel therapeutic approach for severe ARDS with a potent pharmacologic allosteric hemoglobin modifier | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,351,767 | January 1, 2021 | June 30, 2027 | LIGHT, DAVID RICHARD | reporter.nih.gov |
| Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,334,792 | July 1, 2019 | June 30, 2025 | YEHYA, NADIR | reporter.nih.gov |
| 1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $2,334,469 | November 1, 2021 | February 28, 2025 | VIDAL MELO, MARCOS F | reporter.nih.gov |
| Optimization of AEOL10150 treatment of sulfur mustard-induced lung toxidrome in a pig model | NIH | National Institute of Environmental Health Sciences | 2021 to 2023 | $2,332,659 | September 1, 2018 | May 31, 2025 | DAY, BRIAN J | reporter.nih.gov |
| Molecular characterization of pulmonary edema: a window to an injured lung | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,319,669 | August 9, 2020 | May 31, 2025 | ROGERS, ANGELA J | reporter.nih.gov |
| IL-33 induced-lL-9 producing type 2 innate lymphoid cells in the regulation of acute lung injury after hematopoietic stem cell transplantation (HSCT) in pediatric patients | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,303,969 | January 1, 2022 | June 30, 2026 | PACZESNY, SOPHIE | reporter.nih.gov |
| Preclinical development of a synthetic lung surfactant dry powder aerosol for hypoxemia or acute respiratory distress syndrome patients receiving different modes of ventilation support | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,301,184 | July 1, 2023 | June 30, 2027 | LONGEST, P. WORTH | reporter.nih.gov |
| Amplification Mechanisms of Lung Endothelial Inflammation During Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,286,853 | January 15, 2021 | December 31, 2025 | REHMAN, JALEES | reporter.nih.gov |
| LOX-1 as a protective countermeasure in response to lung infection | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,274,599 | June 15, 2023 | May 31, 2027 | QUINTON, LEE | reporter.nih.gov |
| Immune Checkpoints in Acute Respiratory Distress Syndrome (IC-ARDS) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,270,999 | September 5, 2020 | June 30, 2026 | MIKACENIC, CARMEN R | reporter.nih.gov |
| Haptoglobin 2 variant and endothelial glycocalyx shedding in sepsis-induced ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,262,811 | September 1, 2021 | July 31, 2025 | WARE, LORRAINE B | reporter.nih.gov |
| GasderminD regulation of Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,261,470 | August 5, 2022 | June 30, 2027 | SARKAR, ANASUYA | reporter.nih.gov |
| Implementation of behavioral economic approaches to improve evidence uptake for mechanically ventilated patients | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,229,594 | March 15, 2019 | February 28, 2026 | KERLIN, MEETA PRASAD | reporter.nih.gov |
| Advancing the design, analysis, and interpretation of acute respiratory distress syndrome trials using modern statistical tools | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,223,433 | June 1, 2023 | May 31, 2028 | HARHAY, MICHAEL OSCAR | reporter.nih.gov |
| Targeting RIPK3 in Flu-Associated Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $2,222,961 | September 18, 2019 | August 31, 2025 | BALACHANDRAN, SIDDHARTH | reporter.nih.gov |
| microRNA miR-147 Dampens Alveolar Epithelial Inflammation During ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,222,135 | December 15, 2020 | November 30, 2024 | ELTZSCHIG, HOLGER K. | reporter.nih.gov |
| Targeting the eNAMPT/TLR4 pathway to reduce Inflammatory Bowel Disease severity | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2024 | $2,219,663 | September 19, 2022 | July 31, 2025 | GARCIA, JOE G. N. | reporter.nih.gov |
| Mechanisms linking the plasminogen/fibrinogen axis to the pathogenesis of COVID-19 | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,206,716 | September 1, 2021 | July 31, 2025 | FLICK, MATTHEW J. | reporter.nih.gov |
| Identifying patient subgroups and processes of care that cause outcome differences following ICU vs. ward triage among patients with acute respiratory failure and sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,204,852 | September 1, 2023 | June 30, 2027 | ANESI, GEORGE L | reporter.nih.gov |
| Trek-1 Potassium Channels Protect from Hyperoxia-induced Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,202,706 | March 1, 2020 | February 28, 2026 | SCHWINGSHACKL, ANDREAS | reporter.nih.gov |
| Coordinated regeneration of lung epithelial and endothelial compartments | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,201,693 | August 20, 2022 | July 31, 2026 | VAUGHAN, ANDREW | reporter.nih.gov |
| Alcohol and Burn Trauma: Multi-organ Inflammatory Responses | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $2,191,572 | September 20, 2019 | June 30, 2029 | KOVACS, ELIZABETH J. | reporter.nih.gov |
| Point-of-care micro-gas chromatography device for diagnosis and monitoring of acute respiratory distress syndrome using exhaled breath signatures | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,188,590 | January 1, 2024 | December 31, 2027 | FAN, XUDONG | reporter.nih.gov |
| ISGylation regulates lung endothelial inflammation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,180,291 | April 20, 2021 | March 31, 2026 | ZHAO, YUTONG | reporter.nih.gov |
| ENdotypes in Children with Severe Acute Respiratory Distress SyNdrome: ImpAct on REsponse to Treatment (ENSNARE) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $2,178,644 | January 1, 2020 | November 30, 2025 | DAHMER, MARY K | reporter.nih.gov |
| Improvement of Organ Function after Severe Hypovolemia | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,155,286 | February 1, 2004 | December 31, 2026 | WANG, PING | reporter.nih.gov |
| Immune, hormonal, and muscle mitochondrial determinants of recovery in Acute Respiratory Distress Syndrome survivors | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,151,841 | September 1, 2023 | July 31, 2028 | BALDWIN, MATTHEW R | reporter.nih.gov |
| 1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study | NIH | National Heart, Lung, and Blood Institute | 2021 | $2,151,566 | March 19, 2019 | October 31, 2021 | VIDAL MELO, MARCOS F | reporter.nih.gov |
| MAP2K1 AND MAP2K2 IN ACUTE LUNG INJURY AND RESOLUTION | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,151,208 | August 24, 2023 | July 31, 2027 | MANICONE, ANNE M. | reporter.nih.gov |
| PAD2 and CitH3 in Pathogenesis of Sepsis-induced ALI | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,107,087 | September 1, 2021 | August 31, 2025 | LI, YONGQING | reporter.nih.gov |
| TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,097,481 | February 1, 2021 | January 31, 2027 | SCHERAGA, RACHEL GREENBERG | reporter.nih.gov |
| Alveolar responses to viral lung infection | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $2,088,426 | June 20, 2022 | May 31, 2027 | HOOK, JAIME LYNN | reporter.nih.gov |
| Red blood cell ATP export and transfusion in sepsis | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,086,031 | March 5, 2023 | December 31, 2026 | MCMAHON, TIMOTHY J | reporter.nih.gov |
| Mitochondrial DNA Injury is a Key Contributor to the Development of Chemical Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,073,978 | August 1, 1987 | February 28, 2027 | MATALON, SADIS | reporter.nih.gov |
| MAM Proteins in Lung Vascular Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,070,740 | May 1, 2023 | April 30, 2027 | FAZAL, FABEHA | reporter.nih.gov |
| Transcription Factor Elf2 Signals Resolution of Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $2,068,307 | March 15, 2021 | February 28, 2026 | TIRUPPATHI, CHINNASWAMY | reporter.nih.gov |
| Pulmonary arteriole occlusion by platelet-neutrophil micro-emboli in Acute Chest Syndrome | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $2,061,301 | August 15, 2015 | June 30, 2027 | SUNDD, PRITHU | reporter.nih.gov |
| mRNA-LNPs for ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,057,699 | June 12, 2023 | May 31, 2027 | PARHIZ, HAMIDEH | reporter.nih.gov |
| Functional Role of HIF-PHDs in ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,051,945 | September 1, 2023 | August 31, 2027 | ELTZSCHIG, HOLGER K. | reporter.nih.gov |
| Optimizing Time-Limited Trials of Mechanical Ventilation in Acute Respiratory Failure: A Mixed Methods Observational Study | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,050,818 | June 1, 2023 | April 30, 2028 | KRUSER, JACQUELINE MARIE | reporter.nih.gov |
| Preserving Epithelial Barrier Integrity in Ventilator-Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $2,033,122 | September 10, 2018 | March 31, 2028 | BATES, JASON HT | reporter.nih.gov |
| Targeting inflammation and oxidative stress to treat acute lung injury with CNP-miR146a | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $2,024,083 | April 1, 2022 | August 31, 2025 | JACKSON, DAVID | reporter.nih.gov |
| Cellular and molecular mechanisms of alveolar repair | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $2,019,414 | August 1, 2023 | May 31, 2027 | DESAI, TUSHAR JASUBHAI | reporter.nih.gov |
| A Novel Synthetic Biology-Derived Microbiome Therapeutic to Treat Viral-Induced Acute Respiratory Distress Syndrome (ARDS) | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $2,011,001 | January 17, 2023 | December 31, 2025 | FURLAN FREGUIA, CHRISTIAN | reporter.nih.gov |
| Preclinical development of an immunomodulatory agent capable of mitigating SARS-CoV-2 virus related hypercytokinemia | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $2,000,000 | March 6, 2021 | February 29, 2024 | CRAIGO, JODI K | reporter.nih.gov |
| Development of Sotair for Improving Performance and Minimizing Complications of Manual Ventilation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $1,999,740 | September 22, 2022 | June 30, 2025 | PRABHUDESAI, PRATHAMESH | reporter.nih.gov |
| Development of lung T cell responses in infant respiratory immunity | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $1,998,566 | December 3, 2020 | July 31, 2023 | FARBER, DONNA L. | reporter.nih.gov |
| Phase 1/2a Clinical Study of Descartes-30 in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,998,233 | May 1, 2021 | April 30, 2024 | STEWART, CHARLES ANDREW | reporter.nih.gov |
| Targeting integrin outside-in signaling for treating sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,993,937 | September 1, 2018 | May 31, 2025 | SKIDGEL, RANDAL A | reporter.nih.gov |
| Translational Metabolomics in Critical Care | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,981,512 | April 1, 2020 | January 31, 2030 | STRINGER, KATHLEEN A | reporter.nih.gov |
| CMC of Peptide Formulation for the Treatment of ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $1,967,733 | June 1, 2022 | May 31, 2025 | CASTILLO, GERARDO M. | reporter.nih.gov |
| Pathobiology of MRSA-induced Endothelial Permeability and Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,963,994 | December 20, 2022 | November 30, 2026 | DUDEK, STEVEN M | reporter.nih.gov |
| Precision Medicine in Sepsis with Critical Illness | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,953,750 | August 1, 2021 | June 30, 2027 | SINHA, PRATIK | reporter.nih.gov |
| Point of Care Lung CT for Patients with Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,950,570 | September 17, 2021 | May 31, 2025 | VANKAMPEN, WILLIAM CHARLES | reporter.nih.gov |
| Functional diversity of lung pericytes in lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,899,368 | December 15, 2022 | November 30, 2027 | HUNG, CHI F | reporter.nih.gov |
| Health expectations after acute respiratory failure in survivor-care partner dyads | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,882,405 | August 23, 2023 | July 31, 2028 | TURNBULL, ALISON | reporter.nih.gov |
| Peri-operative factors that drive cell-free hemoglobin-mediated primary graft dysfunction | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,864,753 | August 5, 2022 | July 31, 2027 | SHAVER, CIARA M | reporter.nih.gov |
| Peritoneal Oxygen Delivery For The Treatment Of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,864,459 | February 9, 2020 | January 31, 2025 | BORDEN, MARK ANDREW | reporter.nih.gov |
| CMKLR1-Targeted Molecular Imaging of Inflammation as a Precision Medicine Tool in Acute Lung Injury and Fibrotic Lung Diseases | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,859,720 | September 1, 2023 | July 31, 2028 | TAVAKOLI, SINA | reporter.nih.gov |
| Mechanisms of microvascular endothelial cell injury caused by extracellular histones | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $1,849,414 | September 1, 2021 | July 31, 2026 | BIRUKOVA, ANNA | reporter.nih.gov |
| GPR68 as a novel modulator of septic lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,838,568 | August 1, 2023 | July 31, 2027 | BIRUKOVA, ANNA | reporter.nih.gov |
| Organizational resilience: A novel strategy for improving ICU outcomes | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,821,673 | May 1, 2023 | March 31, 2028 | COSTA, DEENA KELLY | reporter.nih.gov |
| Elucidation of a Eukaryotic Chemorepulsion Mechanism | NIH | National Institute of General Medical Sciences | 2021 to 2025 | $1,816,077 | January 1, 2021 | December 31, 2025 | GOMER, RICHARD H | reporter.nih.gov |
| Individualized Prediction of Treatment Effects Using Data from Both Embedded Clinical Trials and Electronic Health Records | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $1,791,807 | September 15, 2022 | July 31, 2025 | COOPER, GREGORY F. | reporter.nih.gov |
| Targeting mechanisms activating ion-channel for preventing acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,786,882 | March 15, 2023 | January 31, 2027 | MEHTA, DOLLY | reporter.nih.gov |
| Molecular regulation of immunoproteasome assembly in inflammatory diseases | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,784,247 | July 1, 2023 | June 30, 2027 | ZHAO, JING | reporter.nih.gov |
| Mitigating Acute Lung Injury by Cell-specific Targeting of MTOR | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,768,287 | June 15, 2020 | May 31, 2025 | RAHMAN, ARSHAD | reporter.nih.gov |
| Therapeutic Use of High Molecular Weight Hyaluronic Acid in Acute Lung Injury Following Severe Bacterial Pneumonia or Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,737,261 | May 1, 2020 | August 31, 2023 | LEE, JAE WOO | reporter.nih.gov |
| A multimodal delivery and treatment approach for Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,731,773 | April 5, 2020 | March 31, 2025 | DEAN, DAVID A | reporter.nih.gov |
| Control of lung permeability by oxidized phospholipids | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,723,566 | June 1, 2004 | May 31, 2025 | BIRUKOV, KONSTANTIN | reporter.nih.gov |
| Defining PRC2 complex epigenomic control in alveolar progenitor cells | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,707,580 | December 15, 2022 | November 30, 2027 | ZACHARIAS, WILLIAM JOHN | reporter.nih.gov |
| Neutrophil Heterogeneity and Immunopathogenesis of COVID-19 ARDS | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,705,089 | January 1, 2023 | December 31, 2027 | YAN, JUN | reporter.nih.gov |
| Novel mechanisms of endothelial Injury in the pathogenesis of ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,703,458 | May 1, 2020 | April 30, 2025 | ZHAO, YOU-YANG | reporter.nih.gov |
| Control of lung alveolar regeneration by Dot1L/H3K79 methylation | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,697,248 | February 1, 2023 | January 31, 2027 | MORRISEY, EDWARD E | reporter.nih.gov |
| Mechanism and targeting of inflammasome activation in lung inflammation and injury | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2025 | $1,696,153 | February 16, 2023 | January 31, 2028 | LIU, GANG | reporter.nih.gov |
| A redox-sensitive switch in the macrophage nucleus regulates acute phase inflammatory injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2024 | $1,671,361 | June 1, 2022 | May 31, 2026 | BONINI, MARCELO G. | reporter.nih.gov |
| Examining the role of TRMT1 and tRNA methylation in acute lung injury and ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,649,733 | July 1, 2023 | June 30, 2028 | LONDINO, JAMES DAVID | reporter.nih.gov |
| Imaging the Pulmonary Circulation to Aid Personalized Management of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,647,868 | July 29, 2024 | June 30, 2029 | CEREDA, MAURIZIO FRANCO | reporter.nih.gov |
| Role of heme and PGP matrikines in lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,641,507 | September 1, 2020 | July 31, 2025 | PATEL, RAKESH P. | reporter.nih.gov |
| Targeting Myeloid Dependent MicroRNAs in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,628,000 | February 1, 2022 | January 31, 2027 | YUAN, XIAOYI | reporter.nih.gov |
| Nanomedicine for ARDS: A new paradigm to target drugs to multiple cell types within alveolar capillaries | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $1,625,000 | July 1, 2020 | June 30, 2025 | BRENNER, JACOB | reporter.nih.gov |
| Supplemental Citicoline Administration for Reduction of Lung Injury Efficacy Trial (SCARLET) | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2024 | $1,614,003 | July 1, 2022 | March 31, 2026 | CROUSER, ELLIOTT D | reporter.nih.gov |
| Targeted treatment of acute lung injury using isolated lung perfusion | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,607,084 | December 20, 2023 | November 30, 2027 | KRON, IRVING L. | reporter.nih.gov |
| CATCH: Creating Access to Transplant for Candidates who are High Risk | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,592,826 | August 5, 2022 | July 31, 2027 | KESHAVJEE, SHAF | reporter.nih.gov |
| Complementary pathways of necroptosis in recipient and donor lung tissue that drive primary lung allograft dysfunction | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,584,308 | September 1, 2024 | June 30, 2029 | BHARAT, ANKIT | reporter.nih.gov |
| Biophysical Mechanisms of Hyperoxia-Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,566,993 | April 15, 2020 | March 31, 2025 | WATERS, CHRISTOPHER M | reporter.nih.gov |
| The Role of TREK-1 potassium channels in ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,564,724 | August 16, 2024 | June 30, 2029 | SCHWINGSHACKL, ANDREAS | reporter.nih.gov |
| Induction of myeloid-epithelial gap junctional channels to enhance host resilience against acute lung injury. | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,554,097 | June 17, 2024 | May 31, 2028 | BHATTACHARYA, JAHAR | reporter.nih.gov |
| HDAC9 nuclear/cytoplasmic shuttling in pulmonary vascular endothelial barrier regulation | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,540,000 | April 2, 2022 | March 31, 2026 | VERIN, ALEXANDER D | reporter.nih.gov |
| 1/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER) | NIH | National Heart, Lung, and Blood Institute | 2025 | $1,535,439 | September 15, 2025 | December 31, 2026 | WANG, HENRY E. | reporter.nih.gov |
| Respiratory Drive in Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $1,532,977 | May 1, 2023 | April 30, 2028 | BEITLER, JEREMY R. | reporter.nih.gov |
| Targeting ABL kinases to regulate epithelial cell plasticity and regeneration following injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,520,108 | June 1, 2020 | April 30, 2024 | PENDERGAST, ANN MARIE | reporter.nih.gov |
| Novel intrinsic endothelial stem cells responsible for lung endothelial regeneration and vascular repair in ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,518,266 | December 22, 2023 | November 30, 2027 | ZHAO, YOU-YANG | reporter.nih.gov |
| Alcohol-mediated Clock genes interfere with lung injury and repair | NIH | National Institute on Alcohol Abuse and Alcoholism | 2023 to 2025 | $1,510,124 | March 15, 2023 | February 29, 2028 | SUEBLINVONG, VIRANUJ | reporter.nih.gov |
| E3 Ligase-Mediated Immunosuppression in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,507,608 | February 1, 2010 | June 30, 2026 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| Corticosteroids to Reduce Inflammation in Severe Pancreatitis (CRISP) | NIH | National Institute of Diabetes and Digestive and Kidney Diseases | 2022 to 2025 | $1,506,305 | December 15, 2021 | November 30, 2026 | DONNINO, MICHAEL WILLIAM | reporter.nih.gov |
| Targeting Divergent Roles of Caspase 3 to Promote Endothelial Barrier Recovery | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,504,432 | April 1, 2024 | March 31, 2028 | DAMARLA, MAHENDRA | reporter.nih.gov |
| Promoting algorithmic equity in in-hospital mortality prediction | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,496,371 | September 9, 2024 | May 31, 2029 | KOHN, RACHEL | reporter.nih.gov |
| Impact of Heightened UPR Activation on Inflammasome Responses to Influenza and Secondary Streptococcus pneumoniae Infection in Aged Lung | NIH | National Institute on Aging | 2021 to 2022 | $1,491,600 | May 1, 2018 | April 30, 2024 | STOUT DELGADO, HEATHER WINONA | reporter.nih.gov |
| Pulmonary arteriole occlusion by platelet-neutrophil micro-emboli in Acute Chest Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,488,171 | August 15, 2015 | August 31, 2023 | SUNDD, PRITHU | reporter.nih.gov |
| Emulated Target Trials and Phenotyping in Patients with Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2025 | $1,479,335 | September 23, 2025 | August 31, 2027 | LEHMAN, LI-WEI H | reporter.nih.gov |
| Pathophysiological Mechanisms of Chemical-Induced Acute Lung Injury | NIH | National Institute of Environmental Health Sciences | 2023 to 2025 | $1,467,044 | August 20, 2023 | July 31, 2027 | LEIKAUF, GEORGE DOUGLAS | reporter.nih.gov |
| Soluble adenylyl cyclases in lung endothelial tauopathy | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,451,396 | March 20, 2023 | February 28, 2027 | STEVENS, TROY | reporter.nih.gov |
| Mitochondrial maladaptive response of the lung epithelium to elevated CO2 levels | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,447,472 | April 1, 2024 | March 31, 2028 | SZNAJDER, JACOB I | reporter.nih.gov |
| 1/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI) | NIH | National Heart, Lung, and Blood Institute | 2023 | $1,445,727 | September 1, 2023 | August 31, 2024 | TALMOR, DANIEL STUART | reporter.nih.gov |
| Alveolar macrophage subset ontogeny and differentiation during ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,437,981 | June 30, 2024 | May 31, 2029 | MORRELL, ERIC DOUGLAS | reporter.nih.gov |
| Inflammatory Organ Injury after Pneumonia-Derived Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,430,432 | July 1, 2024 | May 31, 2029 | JEYASEELAN, SAMITHAMBY | reporter.nih.gov |
| Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $1,430,251 | September 1, 2025 | August 31, 2029 | GUPTE, AKSHAY NITIN | reporter.nih.gov |
| Pulmonary Pathophysiologic Mechanisms of Chloropicrin and Phosgene | NIH | National Institute of Environmental Health Sciences | 2023 to 2025 | $1,419,213 | August 15, 2023 | July 31, 2027 | VAN WINKLE, LAURA S | reporter.nih.gov |
| Endothelial antigen presentation to T cells as a pathogenic mechanism in influenza-induced acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,412,604 | March 15, 2021 | February 28, 2027 | ZHANG, LIANGHUI | reporter.nih.gov |
| Microbiome and Nutrition in Severe PARDS | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $1,400,053 | April 1, 2021 | March 31, 2024 | TYPPO, KATRI VANAMO | reporter.nih.gov |
| Novel exosomal niches for alveolar stem cell-bassed repair of ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,397,980 | September 1, 2017 | April 30, 2027 | JI, HONG-LONG | reporter.nih.gov |
| Molecular mechanisms relating Poldip2 to endothelial permeability | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,395,897 | April 1, 2024 | March 31, 2028 | GRIENDLING, KATHY K | reporter.nih.gov |
| Mast Cell Activation as a Common Mechanism of Pulmonary Toxicity by Chemical Threat Agents | NIH | National Institute of Environmental Health Sciences | 2025 | $1,395,741 | September 1, 2025 | August 31, 2028 | BROWN, JARED MICHAEL | reporter.nih.gov |
| Cell Based Immunomodulation to Suppress Lung Inflammation and Promote Repair | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,392,522 | August 16, 2024 | July 31, 2028 | GHANTA, RAVI K | reporter.nih.gov |
| Function and application of lung surfactant proteins | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,382,307 | February 15, 2020 | January 21, 2025 | RAPOPORT, TOM A | reporter.nih.gov |
| Therapeutic modulation of zinc for lung injury and mechanobiology | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,381,362 | April 1, 2019 | March 31, 2025 | BARON, REBECCA M | reporter.nih.gov |
| Halolipid-Neutrophil Extracellular Trap Axis in Halogen Lung Injury | NIH | National Institute of Environmental Health Sciences | 2022 to 2024 | $1,362,899 | August 18, 2022 | July 31, 2025 | FORD, DAVID A. | reporter.nih.gov |
| A novel data science and network analysis approach to quantifying facilitators and barriers of low tidal volume ventilation in an international consortium of medical centers | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,361,801 | September 9, 2018 | May 31, 2025 | WEISS, CURTIS H. | reporter.nih.gov |
| Enhanced Metadata Design, Architecture, and Learning (MeDAL) for Development of Generalizable Deep Learning-based Predictive Analytics from Electronic Health Records | NIH | National Library of Medicine | 2022 to 2025 | $1,343,000 | May 1, 2022 | July 31, 2026 | NEMATI, SHAMIM | reporter.nih.gov |
| Cellular and molecular mapping of ventilator-induced lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,339,736 | March 4, 2024 | February 29, 2028 | DESAI, TUSHAR JASUBHAI | reporter.nih.gov |
| 2/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study. | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,327,020 | March 19, 2019 | February 28, 2026 | PARKER, ROBERT A. | reporter.nih.gov |
| Aerosolized Chemically Modified Tetracycline Nanoformulation for the Treatment of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,314,098 | March 1, 2025 | February 28, 2028 | KOLLISCH-SINGULE, MICHAELA CHRISTINA | reporter.nih.gov |
| Immunotherapy for acute lung injury secondary to influenza | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,310,316 | April 1, 2020 | March 31, 2025 | KNIGHT III, PAUL R | reporter.nih.gov |
| The role of the lung microbiome in oxygen-induced lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,302,667 | July 1, 2019 | June 30, 2024 | DICKSON, ROBERT PICKETT | reporter.nih.gov |
| Deubiquitinating and inhibiting Hsp90 by USP40 mitigates lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,299,915 | June 1, 2020 | April 30, 2026 | ZHAO, JING | reporter.nih.gov |
| Nuclear receptor, PPARg in macrophage polarization, hyperinflammatory gene expression and lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,286,337 | April 1, 2024 | March 31, 2028 | NAGY, LASZLO | reporter.nih.gov |
| Muscle and physical function recovery after acute critical illness | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases | 2023 to 2025 | $1,272,324 | September 18, 2023 | August 31, 2028 | DUPONT-VERSTEEGDEN, ESTHER E | reporter.nih.gov |
| Role of tRNA- and rRNA-derived RNAs in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,253,912 | September 1, 2024 | May 31, 2028 | KIRINO, YOHEI | reporter.nih.gov |
| Achieving High Quality Outcomes for Patients with Acute Respiratory Distress Syndrome: Lessons Learned from Nurses in High Performing Hospitals | NIH | National Institute of Nursing Research | 2023 to 2025 | $1,218,750 | March 27, 2023 | February 28, 2027 | BROOKS CARTHON, JACQUELINE MARGO | reporter.nih.gov |
| Sphingolipids as Novel Therapeutic Targets in Radiation Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,199,250 | April 5, 2020 | March 31, 2025 | JACOBSON, JEFFREY R | reporter.nih.gov |
| Nanoparticle Targeting of Neutrophil Subpopulations in Inflammatory Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,198,434 | August 15, 2019 | June 30, 2024 | MALIK, ASRAR B. | reporter.nih.gov |
| Novel role for CD163 in ozone induced alterations of pulmonary immunity | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $1,191,687 | August 15, 2018 | May 31, 2024 | GOWDY, KYMBERLY MAE | reporter.nih.gov |
| SCH: Heterogenous, dynamic synthetic data: From algorithms to clinical applications | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $1,186,521 | February 1, 2022 | November 30, 2026 | STROHMER, THOMAS | reporter.nih.gov |
| Lung epithelial cell-derived C3 in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $1,181,325 | August 1, 2023 | July 31, 2027 | KULKARNI, HRISHIKESH SATISH | reporter.nih.gov |
| Role of intravascular ERO1@ in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,180,759 | September 21, 2020 | August 31, 2025 | CHO, JAEHYUNG | reporter.nih.gov |
| Macrophage Signaling Pathways in Acute Lung Injury and Resolution | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,180,500 | March 1, 2019 | February 29, 2024 | MANICONE, ANNE M. | reporter.nih.gov |
| The MUltidimenSional phenotyping In Critical care (MUSIC) Consortium: A pathway to precision medicine at the bedside | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,162,536 | May 1, 2023 | April 30, 2029 | WARE, LORRAINE B | reporter.nih.gov |
| Mechanisms of antibody-mediated lung Injury after blood transfusion | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,154,692 | January 1, 2019 | December 31, 2022 | LOONEY, MARK ROBERTS | reporter.nih.gov |
| Modulation of inflammation in aging lung | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,152,592 | March 1, 2020 | January 31, 2025 | BIRUKOV, KONSTANTIN | reporter.nih.gov |
| PET/CT-Guided Personalized Mechanical Ventilation to Minimize Ventilator-Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,151,452 | January 1, 2014 | April 30, 2025 | VIDAL MELO, MARCOS F | reporter.nih.gov |
| Advancing Precision Medicine for ARDS and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2025 | $1,147,992 | April 1, 2025 | March 31, 2032 | CALFEE, CAROLYN | reporter.nih.gov |
| Development of PolyAspirin Particles for Therapeutic Intervention in ALI/ARDS via the Passive Restraint of Neutrophil Function | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,145,863 | March 15, 2020 | February 28, 2025 | SINGER, BENJAMIN HERSCHEL | reporter.nih.gov |
| Colorado APS Clinical Center | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,144,687 | May 1, 2023 | April 30, 2029 | MOSS, MARC | reporter.nih.gov |
| Phenotyping ARDS, Pneumonia, and Sepsis over time to elucidate shared and distinct trajectories ofillness and recovery | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,144,421 | May 1, 2023 | April 30, 2029 | MEYER, NUALA JENNINGS | reporter.nih.gov |
| Mechanisms of host protection against pathogen-associated proteases in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,142,264 | August 1, 2017 | December 31, 2022 | LEE, JANET SOJUNG | reporter.nih.gov |
| Brain neuron damage-mediated respiratory failure and mortality during Cryptococcus-associated immune reconstitution inflammatory syndrome in mice | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $1,141,517 | June 3, 2019 | May 31, 2025 | INOUE, MAKOTO | reporter.nih.gov |
| Great Lakes Clinical Center of the Acute Respiratory Distress Syndrome, Pneumonia and Sepsis (APS) Consortium | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,140,945 | May 1, 2023 | April 30, 2029 | HYZY, ROBERT C | reporter.nih.gov |
| The Intermountain West-Atlantic Center (InterACT) for the APS Phenotyping Consortium | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,133,343 | May 1, 2023 | April 30, 2029 | BROWN, SAMUEL MORRIS | reporter.nih.gov |
| Phosphatase and tensin homolog PTEN actions in polymicrobial sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $1,127,360 | July 15, 2014 | June 30, 2023 | SEREZANI, C. HENRIQUE | reporter.nih.gov |
| The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumonia | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,127,000 | March 20, 2024 | February 28, 2029 | WANG, YUXIN | reporter.nih.gov |
| Evaluating Routine Opioid Use during Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,125,308 | May 3, 2020 | September 30, 2023 | WALKEY, ALLAN J. | reporter.nih.gov |
| Molecular Phenotyping of ARDS, Pneumonia, and Sepsis using Latent Class Analysis and Metagenomic Sequencing | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $1,118,088 | May 1, 2023 | April 30, 2029 | CALFEE, CAROLYN | reporter.nih.gov |
| Mechanisms of host protection against pathogen-associated proteases in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $1,115,035 | September 1, 2016 | August 31, 2025 | LEE, JANET SOJUNG | reporter.nih.gov |
| Identification and optimization of medical countermeasures for phosgene inhalation injuries | NIH | National Institute of Environmental Health Sciences | 2024 to 2025 | $1,109,637 | August 16, 2024 | July 31, 2026 | ACHANTA, SATYANARAYANA | reporter.nih.gov |
| Treatment of Fentanyl Overdose-Induced Respiratory Failure by Low-Dose Dexmedetomidine | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $1,102,741 | September 20, 2020 | August 31, 2025 | HAOUZI, PHILIPPE A | reporter.nih.gov |
| Developing a Novel E3 Ligase based Anti-inflammatory for ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $1,102,297 | February 1, 2022 | January 31, 2025 | MALLAMPALLI, RAMA K | reporter.nih.gov |
| 2/2 Self-directed mobile adaptive coping skills intervention to improve psychological distress symptoms among cardiorespiratory failure survivors: the Blueprint RCT | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,097,933 | February 15, 2024 | January 31, 2029 | MORRIS, CYNTHIA D | reporter.nih.gov |
| Macrophage NUDT21-mediated alternative polyadenylation in lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $1,080,465 | December 15, 2023 | November 30, 2027 | MILLS, TINGTING WENG | reporter.nih.gov |
| Mechanisms of hypoxia-mediated memory impairment in an animal model of acute respiratory failure in preterm survivors | NIH | National Institute of Neurological Disorders and Stroke | 2024 to 2025 | $1,078,174 | August 15, 2024 | July 31, 2029 | BACK, STEPHEN ARTHUR | reporter.nih.gov |
| Inducible HMGB1 antagonist for viral-induced acute lung injury. | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $1,068,694 | August 16, 2023 | July 31, 2025 | BLANCO, JORGE C | reporter.nih.gov |
| 2/1 Arrest Respiratory Failure due to Pneumonia (ARREST PNEUMONIA) | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $1,068,366 | September 15, 2019 | August 31, 2025 | DESAI, MANISHA | reporter.nih.gov |
| Identification of AMD3100 (Plerixafor) as a potential lead compound for chlorine toxicity | NIH | National Institute of Environmental Health Sciences | 2021 to 2023 | $1,047,365 | August 21, 2021 | July 28, 2024 | AGGARWAL, SAURABH | reporter.nih.gov |
| An Agnostic, Host-Direct Survival Cure MCM for Pulmonary Toxicants. | NIH | National Institute of Allergy and Infectious Diseases | 2024 | $999,601 | August 1, 2024 | July 31, 2025 | BUCK, MARTINA | reporter.nih.gov |
| Perivascular macrophages - a new player in regulating endothelial repair following lung vascular injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $961,873 | June 15, 2024 | March 31, 2029 | ZHOU, BISHENG | reporter.nih.gov |
| Interrupting pro-inflammatory pulmonary-vascular cell interactions to reduce pulmonary capillary leak in critically ill children with bronchiolitis | NIH | National Heart, Lung, and Blood Institute | 2025 | $958,850 | September 1, 2025 | May 31, 2029 | PIERCE, RICHARD W | reporter.nih.gov |
| CARMIL1 and Endothelial Barrier Function Regulation | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $958,335 | September 1, 2024 | May 31, 2029 | BELVITCH, PATRICK | reporter.nih.gov |
| Focal adhesion kinase regulation of lung vascular permeability and edemagenesis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $955,672 | January 1, 2007 | March 31, 2025 | MEHTA, DOLLY | reporter.nih.gov |
| DCAF7/HDAC4/TFEB axis in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $943,332 | August 1, 2018 | May 31, 2025 | LIU, YUAN | reporter.nih.gov |
| Role of ERK1/2 signaling in SARS-CoV-2 -induced dysregulated immunity and lung pathology. | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $930,578 | September 6, 2024 | June 30, 2029 | CHANNAPPANAVAR, RUDRAGOUDA | reporter.nih.gov |
| Reactive Oxygen Species in Respiratory Failure, Delirium, and Post-ICU Cognitive Impairment | NIH | National Institute on Aging | 2022 to 2025 | $930,305 | September 15, 2022 | June 30, 2027 | KHAN, SIKANDAR HAYAT | reporter.nih.gov |
| Influence of the lung microbiome on macrophage responses to lung damage | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $899,024 | April 1, 2018 | March 31, 2024 | JAMIESON, AMANDA M | reporter.nih.gov |
| Precision Medicine Approach to Vitamin D3 Administration in Critical Illness | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $887,235 | July 1, 2019 | June 30, 2024 | LEAF, DAVID EVAN | reporter.nih.gov |
| Driving Pressure as a Target for Lung-Protective Ventilation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $885,127 | September 1, 2021 | August 31, 2026 | SAHETYA, SARINA | reporter.nih.gov |
| Lung Injury in ONcologic Stem cell transplants (LIONS) | NIH | National Heart, Lung, and Blood Institute | 2025 | $879,567 | September 15, 2025 | June 30, 2029 | YEHYA, NADIR | reporter.nih.gov |
| Microbiome-host interplay in viral respiratory infections: A tracheostomy cohort | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $863,496 | August 11, 2021 | July 31, 2023 | MANSBACH, JONATHAN M | reporter.nih.gov |
| An Innovative Immune Therapy with Antibiotics to Treat Deadly Excess Inflammation in Sepsis and ARDS Induced from Severe Bacterial Infection in Geriatric Patients | NIH | National Institute on Aging | 2021 to 2025 | $860,725 | September 30, 2021 | May 31, 2027 | ROUSSEL, EUGENE | reporter.nih.gov |
| Predisposition for Lung Injury in Sepsis Survival | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $847,800 | May 1, 2021 | April 30, 2026 | DENSTAEDT, SCOTT JOHN | reporter.nih.gov |
| Characterizing the Impact of Fragmented Care in Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $847,800 | August 15, 2021 | July 31, 2026 | ADMON, ANDREW JOHN | reporter.nih.gov |
| Tissue-specific functional genomics in the acute respiratory distress syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $844,964 | May 1, 2021 | April 30, 2026 | KERCHBERGER, VERN ERIC | reporter.nih.gov |
| Developing and Evaluating Quality-Weighted Hospital-Free Days as a Novel, Patient-Centered Outcome for Trials of Patients with Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $843,557 | August 5, 2022 | August 31, 2026 | AURIEMMA, CATHERINE LOUISE | reporter.nih.gov |
| The role of MAP3K2/3 in modulating neutrophil ROS release and its translational potential | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $837,500 | December 24, 2018 | November 30, 2023 | TANG, WENWEN | reporter.nih.gov |
| PET/CT-Guided Personalized Mechanical Ventilation to Minimize Ventilator-Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $827,878 | January 1, 2014 | October 31, 2021 | VIDAL MELO, MARCOS F | reporter.nih.gov |
| New genetic models for C5a receptors | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $825,000 | July 1, 2018 | June 30, 2024 | BOSMANN, MARKUS | reporter.nih.gov |
| Respiratory Drive in Acute Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2025 | $822,882 | January 15, 2025 | August 31, 2028 | BEITLER, JEREMY R. | reporter.nih.gov |
| 1/2 Self-directed mobile adaptive coping skills intervention to improve psychological distress symptoms among cardiorespiratory failure survivors: the Blueprint RCT | NIH | National Heart, Lung, and Blood Institute | 2024 | $820,823 | February 15, 2024 | January 31, 2025 | COX, CHRISTOPHER ETHAN | reporter.nih.gov |
| Preclinical development of an immunomodulatory agent capable of mitigating influenza related hypercytokinemia | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $813,514 | May 8, 2020 | April 30, 2023 | CRAIGO, JODI K | reporter.nih.gov |
| Predicting and Preventing Acute Respiratory Distress Syndrome after Hematopoietic Stem Cell Transplantation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $813,328 | September 1, 2021 | August 31, 2026 | YADAV, HEMANG | reporter.nih.gov |
| Effects of Exercise on Inflammation-Induced Lung and Muscle Injury in Critical Illness (NEXIS-FLAME) | NIH | National Heart, Lung, and Blood Institute | 2021 | $810,859 | September 15, 2018 | June 30, 2023 | STAPLETON, RENEE D | reporter.nih.gov |
| IL-33 signaling as a target to reduce ventilator-induced lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2022 | $810,172 | September 21, 2022 | August 31, 2024 | MUSCH, GUIDO | reporter.nih.gov |
| Lung-Brain Axis as a Mediator of Delirium | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $809,080 | August 1, 2021 | June 30, 2026 | HIPPENSTEEL, JOSEPH ALAN | reporter.nih.gov |
| Implantable Bio-Artificial Pancreas (iBAP) | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $806,915 | September 26, 2017 | June 30, 2022 | ROY, SHUVO | reporter.nih.gov |
| Mechanisms of regulatory T-cell mediated endothelial repair following viral pneumonia in aged hosts | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $805,882 | September 20, 2021 | August 31, 2026 | MORALES-NEBREDA, LUISA | reporter.nih.gov |
| 2/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $801,778 | September 16, 2020 | August 31, 2025 | LEISENRING, WENDY M | reporter.nih.gov |
| 1/2 Self-directed mobile adaptive coping skills intervention to improve psychological distress symptoms among cardiorespiratory failure survivors: the Blueprint RCT | NIH | National Heart, Lung, and Blood Institute | 2025 | $796,582 | February 15, 2024 | January 31, 2029 | COX, CHRISTOPHER ETHAN | reporter.nih.gov |
| Chemokine receptor signaling and the dynamics of neutrophil phenotypes during inflammatory lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $796,189 | September 1, 2025 | June 30, 2029 | REHMAN, JALEES | reporter.nih.gov |
| Obstructive Sleep Apnea and Subclinical Lung Injury in Health and Disease | NIH | National Heart, Lung, and Blood Institute | 2021 | $793,565 | January 15, 2018 | December 31, 2024 | JELIC, SANJA | reporter.nih.gov |
| Identifying Novel Roles and the Therapeutic Potential of the Thrombin Receptor Protease Activated Receptor-1 (PAR1) in Lung Lymphatic Function and Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2025 | $791,503 | September 15, 2025 | June 30, 2029 | REED, HASINA OUTTZ | reporter.nih.gov |
| Developing EPR tools for preclinical interrogation of redox regulation mechanisms contributing to acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $786,623 | April 22, 2021 | March 31, 2024 | NOZIK, EVA S. | reporter.nih.gov |
| Integrated Host/Microbe (IHM) Metagenomics of the Lower Airway to Diagnose PediatricRespiratory Infections, Identify Etiologic Pathogens, and Predict Outcomes | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $781,129 | January 1, 2025 | December 31, 2029 | LANGELIER, CHARLES | reporter.nih.gov |
| How HIV-related proteins increase the susceptibility to lung injury despite anti-retroviral therapy | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $780,000 | January 15, 2019 | December 31, 2024 | GUIDOT, DAVID MARSHALL | reporter.nih.gov |
| The Impact of Fluid Resuscitation on Glycocalyx Degradation in Septic Shock | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $777,496 | September 1, 2019 | May 31, 2025 | SHAPIRO, NATHAN I | reporter.nih.gov |
| The effect of endogenous and exogenous glucocorticoids acting through regulatory T cells on resolution of ALI and the contribution of host genetic variability. | NIH | National Heart, Lung, and Blood Institute | 2025 | $775,992 | February 1, 2025 | November 30, 2029 | MOCK, JASON ROBERT | reporter.nih.gov |
| Spatiotemporal control of early matricellular events in the injured lung | NIH | National Heart, Lung, and Blood Institute | 2025 | $773,446 | January 15, 2025 | November 30, 2028 | LEE, JANET SOJUNG | reporter.nih.gov |
| Role and Mitigation of Inflammasomes and Inflammation During COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $768,215 | September 1, 2021 | June 30, 2022 | TING, JENNY P | reporter.nih.gov |
| Point-of-care system to assess the risk of trauma-induced acute respiratory distress syndrome | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $767,824 | March 1, 2023 | January 31, 2026 | WHITE, IAN M | reporter.nih.gov |
| Modifiable Determinants of Mortality in Neonatal Sepsis | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $762,500 | June 1, 2018 | May 31, 2024 | WYNN, JAMES LAWRENCE | reporter.nih.gov |
| Alveolar epithelial glycocalyx resilience in women during ARDS | NIH | National Heart, Lung, and Blood Institute | 2025 | $761,615 | July 21, 2025 | June 30, 2030 | SCHMIDT, ERIC PETER | reporter.nih.gov |
| Human pulmonary neuroendocrine progenitors in lung injury and disease | NIH | National Heart, Lung, and Blood Institute | 2025 | $761,017 | September 1, 2025 | June 30, 2029 | KUO, CHRISTIN SUCHENG | reporter.nih.gov |
| Migration and resolution, lung microenvironment and mechanisms: examining the diverse responses of neutrophils during S. pneumoniae pneumonia and acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $759,983 | May 15, 2025 | February 28, 2029 | DOERSCHUK, CLAIRE M | reporter.nih.gov |
| Improving lung transplant outcomes through the use of imaging in a DBD rat model | NIH | National Heart, Lung, and Blood Institute | 2021 | $759,350 | August 15, 2018 | June 30, 2025 | RIZI, RAHIM R | reporter.nih.gov |
| Improving goals-of-care discussions for patients with chronic life-limiting illness and acute respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $751,680 | August 1, 2022 | July 31, 2027 | LEE, ROBERT YING-FU | reporter.nih.gov |
| SMART-SEPSIS: Sequential MAchine learning for individualized Response to early Treatment in lung SEPSIS | NIH | National Heart, Lung, and Blood Institute | 2025 | $750,561 | August 21, 2025 | May 31, 2029 | PIRRACCHIO, ROMAIN | reporter.nih.gov |
| Novel Therapeutic Antibody Targeting of Extracellular NAMPT in Ventilator-Induced Lung Injury (VILI) | NIH | National Heart, Lung, and Blood Institute | 2021 | $750,000 | June 1, 2019 | April 30, 2022 | GARCIA, JOE G. N. | reporter.nih.gov |
| Putting Implementation into context to advance the management of mechanically ventilated patients. | NIH | National Heart, Lung, and Blood Institute | 2025 | $748,970 | August 15, 2025 | May 31, 2029 | KERLIN, MEETA PRASAD | reporter.nih.gov |
| Role of Macrophages in CBD mediated attenuation of SEB-induced ARDS | NIH | National Institute of General Medical Sciences | 2023 to 2025 | $746,874 | February 1, 2022 | July 31, 2026 | WILSON, KIESHA | reporter.nih.gov |
| Epimetabolic regulation of macrophage activation in the intra-alveolar compartment during acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $744,880 | September 1, 2025 | May 31, 2029 | VOHWINKEL, CHRISTINE U | reporter.nih.gov |
| Psychological support based on positive suggestions in acute respiratory failure patients | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $743,040 | December 24, 2019 | January 31, 2025 | KARNATOVSKAIA, LIOUDMILA | reporter.nih.gov |
| Clinical Implementation of Molecular Phenotypes of Critical Illness | NIH | National Heart, Lung, and Blood Institute | 2025 | $737,815 | January 28, 2025 | November 30, 2028 | SINHA, PRATIK | reporter.nih.gov |
| Impact of Alcohol Misuse on Cognitive and Respiratory Outcomes in COVID-19-associated Acute Respiratory Failure | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2023 | $727,247 | September 22, 2021 | August 31, 2025 | BURNHAM, ELLEN L | reporter.nih.gov |
| Impact of Diet Induced Obesity on Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $725,760 | January 15, 2022 | January 17, 2025 | PLATAKI, MARIA | reporter.nih.gov |
| Pulmonary Immune Regulation of Lung Injury after Pediatric Hematopoietic Cell Transplant | NIH | National Heart, Lung, and Blood Institute | 2025 | $719,882 | August 20, 2025 | May 31, 2030 | ZINTER, MATTHEW SCOTT | reporter.nih.gov |
| Preclinical development of a synthetic lung surfactant dry powder aerosol for acute respiratory distress syndrome patients receiving different modes of ventilation support | NIH | National Heart, Lung, and Blood Institute | 2022 | $719,373 | September 22, 2022 | June 30, 2023 | LONGEST, P. WORTH | reporter.nih.gov |
| Prognostic biomarkers for respiratory failure post hematopoietic cell transplantation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $719,304 | September 1, 2020 | July 31, 2025 | ROWAN, COURTNEY | reporter.nih.gov |
| Airspace Candida Colonization and Lung Injury (AirCCoLIN) | NIH | National Heart, Lung, and Blood Institute | 2025 | $719,195 | August 1, 2025 | April 30, 2030 | KITSIOS, GEORGIOS | reporter.nih.gov |
| Improving Psychological Outcomes for Acute Respiratory Failure Survivors using a Self-Management Intervention | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $719,048 | February 1, 2022 | January 31, 2027 | HOSEY, MEGAN | reporter.nih.gov |
| 1/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $713,484 | September 16, 2020 | March 31, 2022 | BOECKH, MICHAEL J | reporter.nih.gov |
| LOX-1 as a protective countermeasure in response to lung infection | NIH | National Heart, Lung, and Blood Institute | 2022 | $703,500 | September 19, 2022 | June 5, 2023 | QUINTON, LEE | reporter.nih.gov |
| Role of the SFTA2/ADGRF5 signaling axis in alveolar homeostasis | NIH | National Heart, Lung, and Blood Institute | 2025 | $702,103 | September 1, 2025 | June 30, 2029 | BRIDGES, JAMES PATRICK | reporter.nih.gov |
| Imaging the Respiratory Effects of Truncal Adiposity in Acute Hypoxemic Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2025 | $700,857 | September 10, 2025 | June 30, 2030 | CEREDA, MAURIZIO FRANCO | reporter.nih.gov |
| Racial disparities in shared decision making for patients with acute respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $700,545 | September 1, 2022 | August 31, 2027 | ASHANA, DEEPSHIKHA CHARAN | reporter.nih.gov |
| Investigating the Role of HDL-Associated Serum Amyloid A in Sepsis-Induced Acute Lung Injury and Mortality | NIH | National Heart, Lung, and Blood Institute | 2025 | $699,385 | January 1, 2025 | November 30, 2028 | SHRIDAS, PREETHA | reporter.nih.gov |
| Airway Immune Response in Critically Ill Children-Precision Medicine in Children At Risk for Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $695,787 | April 1, 2020 | March 31, 2025 | GRUNWELL, JOCELYN REBECCA | reporter.nih.gov |
| Mito-inflammation and sepsis-induced acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $694,398 | August 21, 2025 | May 31, 2029 | BLACK, STEPHEN M | reporter.nih.gov |
| Modulation of Acute Lung Injury by Type I Interferon Signaling | NIH | National Heart, Lung, and Blood Institute | 2025 | $690,626 | January 1, 2025 | November 30, 2028 | EMMER, BRIAN T | reporter.nih.gov |
| Resilience Endotype-derivation through Parsimonious Analysis and causal Inference of Recovery from Acute Respiratory Distress Syndrome (REPAIR-ARDS) | NIH | National Heart, Lung, and Blood Institute | 2025 | $689,726 | September 15, 2025 | June 30, 2030 | KAMALESWARAN, RISHIKESAN | reporter.nih.gov |
| Active Drug Loading to Nanovesicles for Targeted Drug Delivery | NIH | National Institute of Biomedical Imaging and Bioengineering | 2022 to 2023 | $688,500 | July 3, 2019 | March 31, 2026 | WANG, ZHENJIA | reporter.nih.gov |
| Indole Metabolites as Xenobiotic Danger signals in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $688,163 | September 1, 2025 | May 31, 2029 | EVANKOVICH, JOHN W | reporter.nih.gov |
| 2/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER) | NIH | National Heart, Lung, and Blood Institute | 2025 | $688,047 | September 1, 2025 | August 31, 2031 | DURKALSKI, VALERIE L | reporter.nih.gov |
| T cell modulation of COVID-19 disease | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $686,250 | September 20, 2021 | August 31, 2025 | MANESS, NICHOLAS JAMES | reporter.nih.gov |
| Targeting Estrogenic pathways in Tregs to promote ARDS resolution - 5R01HL163881 | NIH | National Heart, Lung, and Blood Institute | 2025 | $684,280 | August 15, 2025 | May 31, 2027 | D'ALESSIO, FRANCO RAFAEL | reporter.nih.gov |
| Mitochondrial deubiquitinase USP30 regulates cell metabolism-mediated miRNA biogenesis and microvascular inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $678,803 | February 1, 2025 | November 30, 2028 | ZHAO, YUTONG | reporter.nih.gov |
| Role of Macrophage Efferocytosis in Ozone-Induced ARDS | NIH | National Institute of Environmental Health Sciences | 2022 to 2024 | $667,515 | September 22, 2020 | August 31, 2025 | RADBEL, JARED M. | reporter.nih.gov |
| Mitochondrial mechanisms underlying alveolar-capillary barrier regulation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $661,824 | July 15, 2020 | June 30, 2025 | HOUGH, REBECCA FRANCES | reporter.nih.gov |
| Neutrophils in Sepsis: Role of CIRP | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $660,000 | September 1, 2018 | June 30, 2025 | AZIZ, MONOWAR | reporter.nih.gov |
| The role of HMGB1 in the lung response to bacterial injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $656,988 | August 1, 2025 | April 30, 2030 | MESSER, JEANNETTE SOPHIA | reporter.nih.gov |
| Simplifying Bedside Lung Perfusion Imaging Using Electrical Impedance Tomography | NIH | National Institute of Biomedical Imaging and Bioengineering | 2025 | $656,750 | August 1, 2025 | July 31, 2028 | XIN, YI | reporter.nih.gov |
| Operationalizing the RAGE Axis in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $647,998 | March 15, 2020 | February 28, 2026 | JONES, TIFFANIE KAE | reporter.nih.gov |
| CREB Instruction of Macrophage Fate and Lung fluid homeostasis | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $636,406 | September 20, 2021 | May 31, 2026 | MEHTA, DOLLY | reporter.nih.gov |
| Angiopoietin/Tie signaling regulation of vascular leakage in lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2021 | $634,697 | July 1, 2018 | May 31, 2022 | MCDONALD, DONALD M | reporter.nih.gov |
| An integrated approach to predict and improve the outcomes of lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $633,795 | July 1, 2018 | July 1, 2022 | CEREDA, MAURIZIO FRANCO | reporter.nih.gov |
| The influence of ward capacity strain on outcomes among survivors of acute respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $628,488 | August 26, 2019 | April 30, 2025 | KOHN, RACHEL | reporter.nih.gov |
| Mobile Critical Care Recovery Program (m-CCRP) for Acute Respiratory Failure (ARF) Survivors | NIH | National Heart, Lung, and Blood Institute | 2021 | $627,424 | January 10, 2017 | December 31, 2022 | KHAN, BABAR A | reporter.nih.gov |
| Cellular and molecular mechanisms of e-cigarette vaping-induced acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2022 | $616,411 | September 19, 2022 | August 31, 2024 | DI, YUANPU PETER | reporter.nih.gov |
| Improving the fairness of RCTs among patients with acute and chronic respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $615,751 | July 1, 2018 | June 30, 2028 | HALPERN, SCOTT D | reporter.nih.gov |
| A redox-sensitive switch in the macrophage nucleus regulates acute phaseinflammatory injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $613,814 | June 1, 2022 | May 31, 2027 | BONINI, MARCELO G. | reporter.nih.gov |
| B cells for treatment of ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 | $610,236 | September 17, 2024 | August 31, 2025 | HANIDZIAR, DUSAN | reporter.nih.gov |
| Indole Metabolites as Xenobiotic Danger signals in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2024 | $607,952 | September 16, 2024 | August 31, 2025 | EVANKOVICH, JOHN W | reporter.nih.gov |
| Diverse effects of hemin on the endothelium contribute to pulmonary complications of sickle cell disease | NIH | National Heart, Lung, and Blood Institute | 2024 | $607,535 | September 17, 2024 | August 31, 2025 | FRAIDENBURG, DUSTIN | reporter.nih.gov |
| Low Dose Oral Carbon Monoxide Therapeutic for Virus-Induced Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $599,788 | August 11, 2022 | July 31, 2025 | GOMPERTS, EDWARD | reporter.nih.gov |
| A Novel, Host-Directed Therapeutic for the Treatment of Sulfur Mustard Induced Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $595,708 | July 9, 2024 | December 31, 2026 | VERESS, LIVIA AGNES | reporter.nih.gov |
| Lung epithelial cell-derived C3 in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $595,668 | August 1, 2025 | July 31, 2027 | KULKARNI, HRISHIKESH SATISH | reporter.nih.gov |
| Acute Inhibition of TAK1 as a Means to Control COVID-19 Pulmonary Hyperinflammation | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $593,995 | August 1, 2021 | May 31, 2024 | SCARNEO, SCOTT | reporter.nih.gov |
| Mentored Patient Oriented Research in Improving Surrogate Decision Making for Patients with Advanced Respiratory Failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2025 | $586,194 | September 1, 2019 | July 31, 2029 | WHITE, DOUGLAS B | reporter.nih.gov |
| Development and Validation of Correction Equations to Enhance Quality of Infrared Technology | NIH | National Heart, Lung, and Blood Institute | 2025 | $584,575 | September 3, 2025 | May 31, 2030 | BHAVANI, SIVASUBRAMANIUM | reporter.nih.gov |
| Development of Localized T Cell Immunity in Pediatric Respiratory Tract Infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2023 | $583,908 | December 5, 2018 | May 31, 2024 | CONNORS, THOMAS | reporter.nih.gov |
| Targeted delivery of novel miRNA-based therapeutics for pneumonia-induced acute lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $583,152 | September 8, 2022 | August 31, 2025 | AKERLEY, BRIAN | reporter.nih.gov |
| In Vivo Lung Perfusion for the Surgical Treatment of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 | $580,182 | April 15, 2018 | March 31, 2024 | LAUBACH, VICTOR E | reporter.nih.gov |
| Novel cysteinyl leukotriene receptor signaling in regulating cellular, and molecular events in lung inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $579,309 | June 9, 2025 | February 28, 2029 | PARUCHURI, SAILAJA | reporter.nih.gov |
| VENTSAFE™ Life Saving Ventilation for the Treatment of ARDS | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $579,289 | September 1, 2024 | October 31, 2025 | BARKER, DEAN ANTONY | reporter.nih.gov |
| Improved ventilation of the edematous lung | NIH | National Heart, Lung, and Blood Institute | 2023 | $576,525 | February 15, 2013 | August 31, 2025 | PERLMAN, CARRIE E | reporter.nih.gov |
| The Role of Alveolar Mononuclear Phagocytes in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $570,564 | September 1, 2019 | August 31, 2024 | MORRELL, ERIC DOUGLAS | reporter.nih.gov |
| Restoring Endothelial Function After Traumatic Injury to Reduce ARDS and Multi-Organ Dysfunction | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $569,349 | September 5, 2023 | August 31, 2028 | DOUIN, DAVID J. | reporter.nih.gov |
| Optimizing the use of noninvasive respiratory support in the Emergency Department | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $567,863 | February 20, 2023 | January 31, 2028 | GOEL, NEHA NEELAM | reporter.nih.gov |
| Targeting Hypoxia-Inducible Factors (HIFs) for Heart and Lung Disease | NIH | National Heart, Lung, and Blood Institute | 2025 | $564,445 | March 1, 2025 | December 31, 2031 | ELTZSCHIG, HOLGER K. | reporter.nih.gov |
| Endothelial antigen presentation to T cells as a pathogenic mechanism in influenza-induced acute lung injury. | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $564,041 | March 15, 2021 | June 30, 2022 | ZHANG, LIANGHUI | reporter.nih.gov |
| Evolution and resolution of ARDS molecular phenotypes | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $563,847 | May 5, 2023 | April 30, 2028 | SARMA, AARTIK | reporter.nih.gov |
| Pediatric Implantable Artificial Lung | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 | $552,860 | August 1, 1980 | May 31, 2023 | HIRSCHL, RONALD BRUCE | reporter.nih.gov |
| Development of a predictive model and electronic health record-based probability scoring system and dashboard for postoperative respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $550,152 | August 1, 2023 | July 31, 2028 | STOCKING, JACQUELINE C | reporter.nih.gov |
| Targeting TLR Signaling Pathways to Blunt Pathogen-mediated Acute Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $544,376 | February 10, 2017 | January 31, 2023 | VOGEL, STEFANIE N. | reporter.nih.gov |
| Netosis in Trauma mediated Acute Lung Injury | NIH | National Institute of General Medical Sciences | 2021 to 2023 | $540,344 | September 14, 2021 | July 31, 2024 | LEONARD, JENNIFER | reporter.nih.gov |
| Sustainable Implementation of Prone Positioning for the Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $537,069 | August 5, 2023 | July 31, 2028 | HOCHBERG, CHAD | reporter.nih.gov |
| Validation of a microRNA panel to pre-symptomatically predict the risk of radiation-induced fibrosis | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $533,384 | September 2, 2025 | August 31, 2030 | ROGERS, CLAUDE J. | reporter.nih.gov |
| Increasing the Success of ARDS Therapeutic Clinical Trials: Novel Trial Design and Targeting of the P-selectin Pathway | NIH | National Heart, Lung, and Blood Institute | 2022 | $529,354 | September 19, 2022 | August 31, 2024 | BIME, CHRISTIAN | reporter.nih.gov |
| Transcriptional Regulation of Endothelial Cells after Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $524,323 | April 1, 2018 | March 31, 2023 | KALINICHENKO, VLADIMIR | reporter.nih.gov |
| Purinergic Modulation of NKT Cells Ameliorates Hyperoxic Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $518,400 | May 1, 2019 | July 31, 2024 | HANIDZIAR, DUSAN | reporter.nih.gov |
| Development of Novel RhoA Nitration Inhibitory Peptides for the Treatment of Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $516,250 | September 1, 2025 | July 31, 2027 | BLACK, STEPHEN M | reporter.nih.gov |
| Engineered Monothiol Thioredoxin for Treatment of Radiation Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $508,988 | September 24, 2025 | August 31, 2026 | HEIFETZ, PETER B | reporter.nih.gov |
| Inflammasomes: Regulation and Function in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $508,492 | July 1, 1996 | March 31, 2023 | CHOI, MARY E | reporter.nih.gov |
| Impact of gut bacterial metabolites on lung function and disease | NIH | National Heart, Lung, and Blood Institute | 2023 to 2025 | $507,060 | April 1, 2023 | January 31, 2028 | UPADHYAY, VAIBHAV | reporter.nih.gov |
| The Detection, Quantification, and Management of Ventilator Dyssynchrony | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $504,750 | January 15, 2019 | July 31, 2024 | SOTTILE, PETER D | reporter.nih.gov |
| Integration of Sotair with Capnography for Standardizing Manual Ventilation Technique and Improving Patient Outcomes | NIH | National Heart, Lung, and Blood Institute | 2025 | $499,932 | September 17, 2025 | August 31, 2026 | PRABHUDESAI, PRATHAMESH P | reporter.nih.gov |
| Novel animal models to study organ-specific SARS-CoV-2-induced pathology | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $499,125 | November 11, 2022 | October 31, 2025 | TUMANOV, ALEXEI V | reporter.nih.gov |
| Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $498,000 | April 15, 2018 | December 31, 2023 | HARHAY, MICHAEL OSCAR | reporter.nih.gov |
| Cell-free hemoglobin-oxidized LDL-LOX-1 axis and microvascular hyperpermeability during sepsis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $498,000 | August 1, 2024 | July 31, 2027 | MEEGAN, JAMIE E | reporter.nih.gov |
| Mitochondrial metabolic regulation of lung epithelium: alveolar generation and regeneration | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $489,888 | September 17, 2019 | August 31, 2024 | HAN, SEUNGHYE | reporter.nih.gov |
| Unravelling the role of aDb2 as a novel complement receptor in lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $489,500 | July 25, 2025 | June 30, 2027 | KOUTSOGIANNAKI, SOPHIA | reporter.nih.gov |
| Targeting the endocannabinoid signaling in chemical threat agents-induced lung injury | NIH | National Institute of Environmental Health Sciences | 2025 | $489,008 | September 15, 2025 | September 14, 2027 | NAGRE, NAGARAJA | reporter.nih.gov |
| Optimization of anesthetic/sedative regimen for pulmonary pathophysiology in cystic fibrosis patients | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $486,750 | February 4, 2021 | January 31, 2024 | YUKI, KOICHI | reporter.nih.gov |
| Type 2 Immune Responses in Endotoxemia-induced Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $486,109 | July 1, 2025 | June 30, 2027 | JACOBSEN, ELIZABETH A | reporter.nih.gov |
| Phosphorylation Control of Fibroproliferative ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $486,009 | August 1, 2019 | November 30, 2024 | ASCHNER, YAEL | reporter.nih.gov |
| Activation of inflammatory programmed cell death by SARS-CoV-2 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $485,375 | May 1, 2022 | April 30, 2024 | OBERST, ANDREW ATWELL | reporter.nih.gov |
| Degradation of Toll-Like Receptor 8 by RNF216 in response to plasma MicroRNAâs â A Novel Mechanism Regulating Inflammation in Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $484,733 | January 15, 2019 | December 31, 2023 | EVANKOVICH, JOHN W | reporter.nih.gov |
| Functional Outcomes after Prolonged Mechanical Ventilation in Children | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2021 to 2023 | $483,228 | August 1, 2019 | July 31, 2025 | MADDUX, ALINE BERNARD | reporter.nih.gov |
| Aerocyte-mediated Alveolar Epithelial Regeneration following Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $480,990 | January 16, 2025 | November 30, 2028 | ZHOU, BISHENG | reporter.nih.gov |
| Novel exosomal niches for alveolar stem cell-based repair of ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 | $469,701 | September 1, 2017 | April 30, 2023 | JI, HONG-LONG | reporter.nih.gov |
| Acquisition of A Microfluidic Chip-Based System for Cluster Sorting and Dispensing | NIH | Office of the Director, National Institutes of Health | 2021 | $468,700 | May 15, 2021 | May 14, 2022 | CHAN, CHARLES KF | reporter.nih.gov |
| Dynactin 4 regulation of lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $466,844 | January 1, 2018 | November 30, 2022 | CHEN, PETER | reporter.nih.gov |
| Mast Cell Activation as a Common Mechanism of Pulmonary Toxicity by Chemical Threat Agents | NIH | National Institute of Environmental Health Sciences | 2023 | $462,501 | August 20, 2023 | July 31, 2025 | BROWN, JARED MICHAEL | reporter.nih.gov |
| Multiplexed device for rapid coagulopathy testing | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $462,000 | September 15, 2021 | September 14, 2023 | MUNN, LANCE L. | reporter.nih.gov |
| Therapeutic platform to treat disease lung using enucleated mesenchymal stem cells0/01/2021 | NIH | National Heart, Lung, and Blood Institute | 2021 | $454,975 | July 16, 2021 | June 30, 2023 | MOOMIAIE, REMO | reporter.nih.gov |
| Digital pathology for defining myeloid cell-mediated lung injury during acute SARS CoV-2 Infection in hamsters | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $453,750 | September 8, 2022 | August 31, 2025 | MARTINOT, AMANDA | reporter.nih.gov |
| PKG Signaling and Sepsis Induced ALI | NIH | National Heart, Lung, and Blood Institute | 2021 | $450,487 | September 20, 2021 | May 31, 2023 | BLACK, STEPHEN M | reporter.nih.gov |
| Metabolic Energy Crisis Signature Predicts Quality of Life in Survivors of Acute Respiratory Failure | NIH | National Institute of Nursing Research | 2021 to 2022 | $450,471 | May 1, 2021 | April 30, 2024 | LANGLEY, RAYMOND JULIAN | reporter.nih.gov |
| Repurposing thiosulfate for chlorine gas exposure | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $450,291 | August 18, 2021 | July 31, 2024 | DAY, BRIAN J | reporter.nih.gov |
| Randomized Trial of Corticosteroids for Post-Extubation Aspiration | NIH | National Institute on Aging | 2024 to 2025 | $450,153 | September 1, 2024 | August 31, 2027 | MOSS, MARC | reporter.nih.gov |
| Roles of human surfactant collectin variants in the susceptibility of COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $448,250 | July 8, 2022 | June 30, 2025 | WANG, GUIRONG | reporter.nih.gov |
| Developing sulfonium lipid nanoparticles as a novel platform for mRNA delivery | NIH | National Institute of General Medical Sciences | 2025 | $448,250 | August 15, 2025 | June 30, 2030 | LI, YAMIN | reporter.nih.gov |
| Targeting Angiopoietin-2 in ARDS | NIH | National Heart, Lung, and Blood Institute | 2021 | $447,835 | March 16, 2017 | January 31, 2022 | MEYER, NUALA JENNINGS | reporter.nih.gov |
| Experimental and Computational Assessment of the Role of NOX4 in Mitochondrial Dysfunction Associated with ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 | $445,673 | July 1, 2015 | June 30, 2026 | AUDI, SAID H | reporter.nih.gov |
| Tuft Cells Modulate Macrophage Response Following Lung Viral Infection | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $445,500 | February 1, 2022 | January 31, 2025 | QUE, JIANWEN | reporter.nih.gov |
| Extracellular vesicles as mediators of injury in inhaled exposures to toxic chemicals. | NIH | National Institute of Environmental Health Sciences | 2023 | $445,500 | August 17, 2023 | July 31, 2025 | AHMAD, AFTAB | reporter.nih.gov |
| Improved ventilation of the edematous lung | NIH | National Heart, Lung, and Blood Institute | 2021 | $444,595 | February 15, 2013 | September 23, 2023 | PERLMAN, CARRIE E | reporter.nih.gov |
| Inhibition of soluble epoxide hydrolase protects against phosgene-induced lung injuries | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $442,750 | August 9, 2021 | July 31, 2024 | ACHANTA, SATYANARAYANA | reporter.nih.gov |
| Mechanisms of exacerbation of COVID-19 pathogenesis in mice expressing human ACE2 by polycyclic aromatic hydrocarbons (PAHs), and its protection by inhibition of soluble epoxide hydrolase (sEH) | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $441,315 | February 1, 2021 | January 31, 2024 | MOORTHY, BHAGAVATULA | reporter.nih.gov |
| Investigating the Role of Vascular Injury and Physiologic Dead Space in the Acute Respiratory Distress Syndrome - Supplement | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $439,560 | June 15, 2025 | May 31, 2026 | COSTA MONTEIRO, ANA CAROLINA | reporter.nih.gov |
| Early detection and identification of ventilator associated pneumonia | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $437,250 | April 15, 2023 | March 31, 2026 | CORCORAN, TIMOTHY E | reporter.nih.gov |
| Improving Characterization of Individualized Treatment Effects in Critical Illness | NIH | National Institute of General Medical Sciences | 2025 | $437,250 | September 1, 2025 | August 31, 2030 | SHAH, FARAAZ ALI | reporter.nih.gov |
| De Novo Designed Protein Nanoparticle Agonists Targeting the Tie2 Receptor for the Treatment of ARDS and Sepsis in Patients with COVID-19 | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $436,804 | August 1, 2021 | December 31, 2023 | UEDA, GEORGE | reporter.nih.gov |
| PB1-F2 mediates hypoxemia in influenza | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $433,125 | July 2, 2025 | June 30, 2027 | DAVIS, IAN CHRISTOPHER | reporter.nih.gov |
| Cannabinoid-2 receptor signaling in vesicant induced lung injury | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $432,598 | August 18, 2021 | June 30, 2024 | NAGRE, NAGARAJA | reporter.nih.gov |
| Novel treatment for respiratory distress due to SARS-CoV2 infection | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $430,188 | June 11, 2021 | May 31, 2023 | GRIENDLING, KATHY K | reporter.nih.gov |
| Resolution of Diffuse Inflammatory Lung Injury in Neonatal Mice | NIH | National Heart, Lung, and Blood Institute | 2021 | $426,425 | June 15, 2013 | August 31, 2023 | MCGRATH-MORROW, SHARON ANN | reporter.nih.gov |
| Regulation of Endothelial-Neutrophil Interaction and Lung Vascular Permeability in Sepsis | NIH | National Institute of General Medical Sciences | 2021 | $426,189 | September 21, 2018 | August 31, 2023 | RAHMAN, ARSHAD | reporter.nih.gov |
| Combinatorial cytokine-coated macrophages for targeted immunomodulation in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $425,757 | August 1, 2023 | July 31, 2026 | ZHAO, ZONGMIN | reporter.nih.gov |
| Therapeutic efficacies of neutrophil elastase and RIP1 inhibitors in acute lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $424,875 | December 2, 2020 | May 31, 2023 | HABELHAH, HASEM | reporter.nih.gov |
| Investigating Lipid-gene Molecular Profiles of Septic ARDS | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $424,223 | June 10, 2025 | May 31, 2027 | GUIRGIS, FAHEEM W | reporter.nih.gov |
| Targeting macrophages to reduce the combined injury effects of radiation and virus exposure | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $423,500 | May 5, 2022 | April 30, 2024 | MARPLES, BRIAN | reporter.nih.gov |
| The amyloid precursor protein protects against acute lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2023 to 2024 | $423,500 | August 11, 2023 | July 31, 2025 | AUDIA, JONATHON PETER | reporter.nih.gov |
| The Pseudomonas aeruginosa virulence factor ExoU activates pyroptosis | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $423,500 | December 1, 2023 | October 31, 2025 | AUDIA, JONATHON PETER | reporter.nih.gov |
| Mitigation of Chlorine Injury to Mitochondria | NIH | National Institute of Environmental Health Sciences | 2021 to 2022 | $421,688 | September 4, 2021 | August 31, 2023 | MATALON, SADIS | reporter.nih.gov |
| Investigating Lung Injury After Cervical Spinal Cord Injury | NIH | National Institute of Neurological Disorders and Stroke | 2021 | $420,750 | April 1, 2021 | March 31, 2024 | ALILAIN, WARREN JOSEPH | reporter.nih.gov |
| Targeting SARS-CoV-2 induced lung immunopathology using novel genetic mouse models | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $419,072 | May 9, 2022 | April 30, 2025 | TUMANOV, ALEXEI V | reporter.nih.gov |
| MtDNA repair: An isolated pharmacologic target in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $418,430 | April 16, 2012 | June 30, 2023 | GILLESPIE, MARK N | reporter.nih.gov |
| Macrophage Redox State in Sterilizing and Injurious Inflammation | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $418,223 | April 7, 2017 | March 31, 2023 | BONINI, MARCELO G. | reporter.nih.gov |
| Neuroendocrine control of TLR4-dependent inflammation in influenza | NIH | National Institute of Allergy and Infectious Diseases | 2021 to 2022 | $411,250 | May 1, 2021 | April 30, 2024 | SHIREY, KARI ANN | reporter.nih.gov |
| Novel Digital Methods to Evaluate Functional and Pulmonary Outcomes following Pediatric Acute Respiratory Failure | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2023 | $408,794 | August 1, 2023 | July 31, 2025 | MADDUX, ALINE BERNARD | reporter.nih.gov |
| Administrative Supplement to R21: Mechanism and in vivo activity of novel glycan-based therapy against flavivirus endothelial permeability and vascular leak | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $407,743 | March 1, 2020 | February 28, 2023 | HARRIS, EVA | reporter.nih.gov |
| Postdoctoral Research Training in Lung Injury and Inflammation | NIH | National Heart, Lung, and Blood Institute | 2025 | $407,052 | August 1, 2025 | July 31, 2030 | DUDEK, STEVEN M | reporter.nih.gov |
| Targeting glutamine metabolism during the development and resolution of acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $404,262 | August 1, 2019 | May 31, 2025 | VIGELAND, CHRISTINE LEE | reporter.nih.gov |
| Resistin-induced immunosuppression increases susceptibility to infectious lung injury and sepsis during AKI | NIH | National Institute of General Medical Sciences | 2021 to 2022 | $403,193 | August 1, 2020 | July 31, 2023 | BONAVIA, ANTHONY S | reporter.nih.gov |
| The vital role of T404 phosphorylation of STAT2 in post-viral bacterial pneumonia | NIH | National Heart, Lung, and Blood Institute | 2022 | $402,500 | September 1, 2022 | August 31, 2024 | WANG, YUXIN | reporter.nih.gov |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (administrative supplement to 5K23HL171951, Adaptation and pilot testing of a family-centered intervention to improve long- | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $402,117 | July 1, 2025 | June 30, 2026 | WENDLANDT, BLAIR N | reporter.nih.gov |
| Macrophage Pyroptosis Mechanism of Post-Trauma Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $391,250 | July 1, 2018 | June 30, 2024 | FAN, JIE | reporter.nih.gov |
| Restoring immune-vascular axis integrity to alleviate acute lung injury in sepsis | NIH | National Heart, Lung, and Blood Institute | 2022 | $391,250 | September 1, 2022 | August 31, 2024 | PAL, KRISHNENDU | reporter.nih.gov |
| eCIRP-Neutralizing mAb for Acute Lung Injury in Sepsis | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $389,330 | June 1, 2022 | November 30, 2023 | BRENNER, MAX | reporter.nih.gov |
| Mitochondrial Determinants of Cognitive Outcomes in ARDS and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $387,695 | May 1, 2017 | November 30, 2023 | GIRARD, TIMOTHY D | reporter.nih.gov |
| Microbiome and Nutrition in Severe PARDS | NIH | Eunice Kennedy Shriver National Institute of Child Health & Human Development | 2024 | $385,849 | April 1, 2024 | March 31, 2027 | TYPPO, KATRI VANAMO | reporter.nih.gov |
| Development of a platform to non-invasively assess microvascular endothelial dysfunction at the bedside in COVID-19 patients throughout intensive care. | NIH | National Institute of Biomedical Imaging and Bioengineering | 2021 | $385,726 | July 1, 2021 | June 30, 2024 | BUSCH, DAVID RICHARD | reporter.nih.gov |
| Understanding Cell Behavior in Precise Multifunctional Biomimetic Matrices Prepared via 3D Printing | NIH | National Institute of General Medical Sciences | 2025 | $385,671 | September 1, 2025 | August 31, 2030 | PAGE, ZACHARIAH ALLEN | reporter.nih.gov |
| Develop novel iNOS/NO inhibitors for mitigating inflammatory cell death, ARDS, and MODS | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $385,625 | July 7, 2025 | June 30, 2027 | LEI, YUGUO | reporter.nih.gov |
| Oxidized glutathione regulation of epithelial sodium channels in newborn lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 | $384,730 | June 1, 2018 | May 31, 2024 | HELMS, MY N. | reporter.nih.gov |
| Aerosolized Nicotine Modulation of Host Inflammation and Microbiota Dysbiosis | NIH | National Heart, Lung, and Blood Institute | 2021 | $381,250 | January 1, 2017 | December 31, 2021 | GAHRING, LORISE C | reporter.nih.gov |
| Regulation of phosphodiesterases and cAMP signaling during the host-pathogen interaction in the pulmonary endothelium | NIH | National Heart, Lung, and Blood Institute | 2021 | $378,245 | April 1, 2018 | March 31, 2023 | RICHTER, WITO H | reporter.nih.gov |
| Vaping has an immunosuppressive effect, rendering the lung more susceptible to microbial infections | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $375,000 | September 10, 2024 | July 31, 2028 | ONYENWOKE, ROB U | reporter.nih.gov |
| Targeting CD14: A Novel Therapeutic Approach for Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $372,816 | September 1, 2024 | August 31, 2029 | MABREY, FRANCES LINZEE | reporter.nih.gov |
| Neurocognitive Impairment in Acute Respiratory Failure and Shock: Understanding the Role of Neuronal Excitotoxicity | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $371,822 | April 15, 2018 | March 31, 2024 | ANDERSON, BRIAN J. | reporter.nih.gov |
| Molecular Mechanism of Lung Barrier Dysfunction | NIH | National Heart, Lung, and Blood Institute | 2021 | $371,250 | July 1, 2018 | May 31, 2024 | DING, QIANG | reporter.nih.gov |
| Impact of a Disease-Associated Dynactin Variant on Motile Phenomena in Lung Epithelial Cells | NIH | National Heart, Lung, and Blood Institute | 2022 | $366,880 | September 22, 2022 | August 31, 2024 | SCHROER, TRINA A | reporter.nih.gov |
| Integrated Metagenomic and Metatranscriptomic Characterization of Inflammatory Chronic Rhinosinusitis Endotypes | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $365,529 | June 30, 2020 | December 31, 2021 | TURNER, JUSTIN H | reporter.nih.gov |
| Surfactant protein-A regions as TLR4-immunomodulators | NIH | National Heart, Lung, and Blood Institute | 2021 | $362,500 | August 8, 2017 | July 31, 2023 | AWASTHI, SHANJANA | reporter.nih.gov |
| Mentored Patient Oriented Research in ARDS and Critical Illness Outcomes | NIH | National Heart, Lung, and Blood Institute | 2021 to 2023 | $355,659 | August 1, 2020 | July 31, 2025 | HOUGH, CATHERINE LEE | reporter.nih.gov |
| Understanding Response Shift in Acute Respiratory Distress Syndrome (ARDS) survivors | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $352,289 | April 12, 2018 | January 15, 2024 | TURNBULL, ALISON | reporter.nih.gov |
| Role of lung WWOX deficiency in vascular leak during lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $348,344 | August 1, 2018 | July 31, 2024 | SINGLA, SUNIT | reporter.nih.gov |
| SELPLG as a candidate gene in Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $345,384 | April 9, 2018 | March 31, 2023 | BIME, CHRISTIAN | reporter.nih.gov |
| The Impact of Soluble ST2 on Lung Injury Onset and Resolution | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $341,280 | April 1, 2024 | May 31, 2029 | ALLADINA, JEHAN | reporter.nih.gov |
| Regulation of vascular metabolism in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $340,844 | February 1, 2021 | August 31, 2022 | WU, DAVID D | reporter.nih.gov |
| Leveraging Automated Optimization of Inspired Oxygen and Oxidized Biomarker Lipidomics for Targeted Oxygenation during Mechanical Ventilation: a Pragmatic Clinical Trial | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $340,416 | May 19, 2023 | April 30, 2027 | PANNU, SONAL R. | reporter.nih.gov |
| Protective role of Endothelial Receptor Interacting Protein Kinase 3 (RIPK3) in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $338,040 | February 1, 2024 | January 31, 2029 | PRICE, DAVID REGAN | reporter.nih.gov |
| Treatment implications of heterogeneity in acute respiratory failure risk among patients with hospital-onset sepsis | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $335,664 | May 1, 2024 | April 30, 2029 | GINESTRA, JENNIFER CLAIRE | reporter.nih.gov |
| Improving patient- and family-centered outcomes and value of care for patients with chronic illness who develop acute respiratory failure | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $334,980 | August 1, 2019 | July 31, 2024 | KHANDELWAL, NITA | reporter.nih.gov |
| SCD-PICC Therapy for Respiratory Insufficiency associated with COVID-19 in non-ICU settings | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $331,757 | August 15, 2022 | August 14, 2023 | PINO, CHRISTOPHER | reporter.nih.gov |
| Transfer RNAs as novel mediators in acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $327,240 | May 1, 2024 | April 30, 2029 | BEDNASH, JOSEPH STANLEY | reporter.nih.gov |
| Mechanistic evaluation of a novel Wnt-responsive adult alveolar epithelial progenitor population during regeneration after diffuse alveolar damage | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $326,160 | July 21, 2018 | June 30, 2023 | ZACHARIAS, WILLIAM JOHN | reporter.nih.gov |
| Investigating mechanisms of disparities for critically ill patients with acute respiratory failure and sepsis. | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $323,804 | February 1, 2024 | January 31, 2029 | CHESLEY, CHRISTOPHER FRANCIS | reporter.nih.gov |
| Microbiome-based diagnosis of pneumonia in the acute respiratory distress syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $323,786 | January 22, 2018 | December 31, 2022 | KITSIOS, GEORGIOS | reporter.nih.gov |
| Endothelial cell signaling in regeneration of the lung | NIH | National Heart, Lung, and Blood Institute | 2022 to 2023 | $323,380 | September 1, 2022 | December 31, 2023 | NIETHAMER, TERREN KATHRYN | reporter.nih.gov |
| Mechanistic insights of inflammation and organ failure after trauma or critical illness | NIH | National Institute of General Medical Sciences | 2021 | $323,235 | April 1, 2018 | March 31, 2024 | JIN, YANG | reporter.nih.gov |
| Role of miR-181a-5p in Adenovirus 14p1 induced Acute Lung Injury | NIH | National Institute of Allergy and Infectious Diseases | 2022 to 2023 | $320,925 | May 13, 2022 | April 30, 2025 | RADKE, JAY R | reporter.nih.gov |
| Metabolic Reprogramming of Recruited Alveolar Macrophages by Arginine In Acute Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $319,248 | April 9, 2018 | March 31, 2024 | MOULD, KARA J | reporter.nih.gov |
| Repurposing Incyclinide for the Treatment of Hospitalized COVID-19 Patients | NIH | National Center for Advancing Translational Sciences | 2021 | $315,000 | March 1, 2021 | August 31, 2023 | SCADUTO, JOSEPH | reporter.nih.gov |
| A PTP4A3 inhibitor for SARS-CoV-2-mediated acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $313,708 | July 15, 2022 | August 31, 2022 | LAZO, JOHN S. | reporter.nih.gov |
| The Association Between Aging, Inflammation, and Clinical Outcomes in Acute Respiratory Distress Syndrome | NIH | National Institute on Aging | 2023 to 2024 | $309,000 | August 15, 2023 | April 30, 2026 | LEVINE, ANDREA | reporter.nih.gov |
| Developing allogeneic iNKT cell adoptive therapy to improve outcomes for HSCT indications | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $306,500 | May 9, 2025 | April 30, 2027 | LE TONQUEZE, OLIVIER | reporter.nih.gov |
| Development of a Neutrophil Degranulation Inhibitor to Treat ARDS | NIH | National Heart, Lung, and Blood Institute | 2023 | $306,424 | April 1, 2023 | December 31, 2024 | MCLEISH, KENNETH R | reporter.nih.gov |
| Intravenous delivery of oxygen microbubbles for the treatment of hypoxia and ARDS | NIH | National Heart, Lung, and Blood Institute | 2022 | $305,538 | September 20, 2022 | August 31, 2024 | ARCAND, BENJAMIN | reporter.nih.gov |
| Treatment of Inflammatory Complications of Viral Pneumonia | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $300,000 | June 20, 2022 | August 6, 2023 | AGRAWAL, ANDY | reporter.nih.gov |
| Recombinant E-NTPDase for shock | NIH | National Institute of General Medical Sciences | 2023 | $299,999 | September 21, 2023 | August 31, 2025 | HASKO, GEORGE | reporter.nih.gov |
| Aerosol Ventilation to Reduce Ventilator Induced Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2022 | $299,996 | September 23, 2022 | February 29, 2024 | JONES, ANDREW | reporter.nih.gov |
| Development of a Novel Resolvin-Based Therapy for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) | NIH | National Institute of Allergy and Infectious Diseases | 2021 | $299,561 | August 6, 2021 | January 31, 2023 | SCIAVOLINO, FRANK | reporter.nih.gov |
| Targeting inflammation and oxidative stress to treat acute lung injury with CNP-miR146a | NIH | National Heart, Lung, and Blood Institute | 2022 | $299,271 | April 1, 2022 | March 31, 2023 | JACKSON, DAVID | reporter.nih.gov |
| RelianceET: a novel endotracheal tube design with a superior sealing mechanism to improve clinical efficiency and reduce lung injury and infection for patients. | NIH | National Heart, Lung, and Blood Institute | 2024 | $299,101 | May 1, 2024 | June 30, 2025 | BERESFORD, ROSS | reporter.nih.gov |
| Novel therapeutic approach for severe ARDS with a potent pharmacologic allosteric hemoglobin modifier | NIH | National Heart, Lung, and Blood Institute | 2021 | $298,412 | January 1, 2021 | December 31, 2022 | LIGHT, DAVID RICHARD | reporter.nih.gov |
| Optimizing Small Molecule Lipoxin-Mimicking FPR2 Agonists for the Treatment of Acute Respiratory Distress Syndrome | NIH | National Heart, Lung, and Blood Institute | 2021 | $298,015 | September 20, 2021 | August 31, 2023 | GAFFNEY, KEVIN JOHN | reporter.nih.gov |
| Targeted therapeutic delivery to diseased lungs using enucleated mesenchymal stem cells | NIH | National Heart, Lung, and Blood Institute | 2021 | $297,553 | September 20, 2021 | July 31, 2023 | WANG, HUAWEI | reporter.nih.gov |
| Decision Support System for Personalized Care of Ventilated Patients using Esophageal Pressure | NIH | National Heart, Lung, and Blood Institute | 2024 | $295,924 | September 15, 2024 | September 14, 2025 | EULIANO, NEIL R. | reporter.nih.gov |
| Development of a CO2-bicarbonate combined membrane capture system for accessible treatment of acute respiratory failure. | NIH | National Heart, Lung, and Blood Institute | 2021 | $293,121 | September 17, 2021 | May 31, 2022 | CHANG, BRIAN YALE | reporter.nih.gov |
| Novel Stimulation to Improve Respiratory Function in ARDS and Severe COVID-19 Patients | NIH | National Heart, Lung, and Blood Institute | 2022 | $275,405 | June 1, 2022 | May 31, 2024 | HARDIN, BILL | reporter.nih.gov |
| New mechanism-based TREM-1 therapy for acute respiratory distress syndrome | NIH | National Heart, Lung, and Blood Institute | 2023 | $272,741 | August 1, 2023 | October 31, 2024 | SIGALOV, ALEXANDER B | reporter.nih.gov |
| Defining Drivers of mtDNA Levels in Blood Components and Their Impact on Transfusion-Related Lung Injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $262,500 | September 15, 2025 | August 31, 2027 | NORRIS, PHILIP J. | reporter.nih.gov |
| Roles of N-glycans on neutrophil beta2 integrins in progression of acute lung injury | NIH | National Institute of Allergy and Infectious Diseases | 2022 | $262,200 | June 1, 2022 | May 15, 2023 | SHAO, BOJING | reporter.nih.gov |
| Strengthening implementation science in Acute Respiratory Failure using multilevel analysis of existing data | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $261,227 | July 15, 2023 | June 30, 2026 | TURNBULL, ALISON | reporter.nih.gov |
| Targeting the P Selectin Pathway to Improve ARDS Survival | NIH | National Heart, Lung, and Blood Institute | 2022 | $259,613 | September 23, 2022 | September 22, 2023 | MIELE, STANLEY | reporter.nih.gov |
| Protein Regulation and Cytoskeletal Dynamics of Pulmonary Endothelial Barrier Function | NIH | National Heart, Lung, and Blood Institute | 2021 | $256,133 | January 1, 2017 | June 30, 2022 | BELVITCH, PATRICK | reporter.nih.gov |
| Mentoring and Patient-Oriented Research in Clinical Informatics and Data Science | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $251,802 | December 1, 2023 | November 30, 2028 | BENNETT, TELLEN | reporter.nih.gov |
| The role of epigenetic regulator UHRF1 in stability of induced regulatory T-cell function during influenza A virus-induced lung injury | NIH | National Heart, Lung, and Blood Institute | 2022 to 2025 | $250,698 | March 1, 2023 | February 28, 2026 | JOUDI, ANTHONY | reporter.nih.gov |
| First-in-class small molecules that enhance lung barrier function during acute respiratory distress syndrome (ARDS) as potential therapeutics for COVID-19 | NIH | National Heart, Lung, and Blood Institute | 2021 | $249,998 | July 1, 2021 | December 31, 2023 | AUSUBEL, FREDERICK M | reporter.nih.gov |
| Protective role of B cells in hyperoxic lung injury | NIH | National Heart, Lung, and Blood Institute | 2024 to 2025 | $249,072 | August 1, 2024 | July 31, 2026 | HANIDZIAR, DUSAN | reporter.nih.gov |
| Targeted mRNA therapies treating ARDS | NIH | National Heart, Lung, and Blood Institute | 2025 | $249,000 | August 16, 2025 | July 31, 2028 | ZHOU, ZHENGJIE | reporter.nih.gov |
| Regulation of Pathologic Inflammasome Responses to SARS-CoV-2 | NIH | National Institute of Allergy and Infectious Diseases | 2025 | $249,000 | May 23, 2024 | July 31, 2027 | BARNETT, KATHERINE CAMILLE | reporter.nih.gov |
| Early, non-invasive detection of pulmonary vascular dysfunction in acute respiratory distress syndrome | NIH | National Heart, Lung, and Blood Institute | 2025 | $247,500 | September 1, 2025 | August 31, 2027 | ALBA, GEORGE A | reporter.nih.gov |
| Role of NOD2 in Acute Lung Injury Following Ischemic Kidney Injury | NIH | National Heart, Lung, and Blood Institute | 2021 to 2024 | $245,546 | July 1, 2022 | June 30, 2025 | DEWOLF, SEAN EDWARD | reporter.nih.gov |
| 2/2 Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis | NIH | National Heart, Lung, and Blood Institute | 2021 | $243,200 | September 16, 2020 | March 31, 2022 | HUANG, YING | reporter.nih.gov |
| Specialized pro-resolving mediators as potential medical countermeasures in a pig model of chlorine gas-induced acute lung injury | NIH | National Institute of Environmental Health Sciences | 2021 | $241,500 | May 1, 2020 | April 30, 2023 | ACHANTA, SATYANARAYANA | reporter.nih.gov |
| Precision Medicine for Nutrition in EDEN | NIH | National Heart, Lung, and Blood Institute | 2023 to 2024 | $238,500 | April 1, 2023 | March 31, 2026 | SHAH, FARAAZ ALI | reporter.nih.gov |
| Discovery of Novel Anti-inflammatory, Non-immunosuppressive Molecules forMitigation of Cytokine Storm in COVID-19 Patients | NIH | National Heart, Lung, and Blood Institute | 2022 | $236,387 | May 1, 2022 | December 31, 2023 | MOGHADDAM, MEHRAN F | reporter.nih.gov |
| Regulation of dendritic cell function by neutrophil-derived reactive oxygen species in pulmonary aspergillosis | NIH | National Heart, Lung, and Blood Institute | 2021 | $234,036 | May 3, 2017 | April 30, 2023 | CAGNINA, REBECCA ELAINE | reporter.nih.gov |
| Tuning complement-mediated immunity in aspergillosis: a systems medicine approach | NIH | National Institute of Allergy and Infectious Diseases | 2024 to 2025 | $233,688 | December 7, 2023 | November 30, 2028 | SORDO VIEIRA, LUIS ALFONSO | reporter.nih.gov |
| The role of lipid metabolism in lung macrophage activity and phenotypes during acute lung injury | NIH | National Heart, Lung, and Blood Institute | 2025 | $233,250 | September 1, 2025 | August 31, 2027 | VIGELAND, CHRISTINE LEE | reporter.nih.gov |
| Role of Endothelial eNAMPT Secretion and TLR4 Signaling in the ARDS Vascular Endotype | NIH | National Heart, Lung, and Blood Institute | 2022 | $232,675 | May 20, 2022 | August 30, 2022 | GARCIA, JOE G. N. | reporter.nih.gov |
| Patient-Oriented Research in Acute Lung Injury and Host Defense in the ICU | NIH | National Heart, Lung, and Blood Institute | 2021 to 2022 | $230,577 | May 15, 2019 | December 31, 2022 | LEE, JANET SOJUNG | reporter.nih.gov |
| Prevalence of ICU-Acquired Myopathy in Patients with Alcohol Use Disorders | NIH | National Institute on Alcohol Abuse and Alcoholism | 2021 to 2022 | $224,370 | May 1, 2018 | April 30, 2023 | JOLLEY, SARAH E | reporter.nih.gov |
Organizations
| Organization | Place | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|---|
| University of Pennsylvania | Philadelphia, PA | 35 | $43.3 million | 0 | $0 |
| Vanderbilt University Medical Center | Nashville, TN | 11 | $30.5 million | 0 | $0 |
| University of Pittsburgh at Pittsburgh | Pittsburgh, PA | 30 | $28.5 million | 0 | $0 |
| University of California, San Francisco | San Francisco, CA | 24 | $23.8 million | 0 | $0 |
| Ohio State University | Columbus, OH | 17 | $23.6 million | 0 | $0 |
| Louisiana State University | Baton Rouge, LA | 3 | $22.8 million | 0 | $0 |
| University of Colorado Denver | Aurora, CO | 28 | $22.1 million | 0 | $0 |
| University of Illinois at Chicago | Chicago, IL | 22 | $21.2 million | 0 | $0 |
| University of Michigan at Ann Arbor | Ann Arbor, MI | 16 | $19 million | 0 | $0 |
| Columbia University Health Sciences | New York, NY | 14 | $18.9 million | 0 | $0 |
| Univ of North Carolina Chapel Hill | Chapel Hill, NC | 13 | $17.2 million | 0 | $0 |
| Massachusetts General Hospital | Boston, MA | 18 | $16.7 million | 0 | $0 |
| University of Washington | Seattle, WA | 16 | $16.6 million | 0 | $0 |
| Weill Medical Coll of Cornell Univ | New York, NY | 7 | $14 million | 0 | $0 |
| Stanford University | Stanford, CA | 8 | $13.8 million | 0 | $0 |
| Northwestern University at Chicago | Chicago, IL | 14 | $13 million | 0 | $0 |
| University of Alabama at Birmingham | Birmingham, AL | 9 | $11.2 million | 0 | $0 |
| Johns Hopkins University | Baltimore, MD | 15 | $10.8 million | 0 | $0 |
| National Jewish Health | Denver, CO | 6 | $10.4 million | 0 | $0 |
| Beth Israel Deaconess Medical Center | Boston, MA | 5 | $9.3 million | 0 | $0 |
| Fred Hutchinson Cancer Center | Seattle, WA | 2 | $8.8 million | 0 | $0 |
| Duke University | Durham, NC | 11 | $8.6 million | 0 | $0 |
| University of Maryland Baltimore | Baltimore, MD | 7 | $7.8 million | 0 | $0 |
| University of California, San Diego | La Jolla, CA | 7 | $7.8 million | 0 | $0 |
| Washington University | Saint Louis, MO | 8 | $7.6 million | 0 | $0 |
| University of Texas HLTH Sci CTR Houston | Houston, TX | 5 | $7.5 million | 0 | $0 |
| Yale University | New Haven, CT | 5 | $6.6 million | 0 | $0 |
| Children's Hosp of Philadelphia | Philadelphia, PA | 4 | $6.6 million | 0 | $0 |
| University of Rochester | Rochester, NY | 5 | $6.4 million | 0 | $0 |
| Lurie Children's Hospital of Chicago | Chicago, IL | 4 | $6 million | 0 | $0 |
| Rhode Island Hospital | Providence, RI | 2 | $6 million | 0 | $0 |
| Emory University | Atlanta, GA | 11 | $5.9 million | 0 | $0 |
| University of California at Davis | Davis, CA | 5 | $5.7 million | 0 | $0 |
| Aqualung Therapeutics Corp. | Juno Beach, FL | 4 | $5.7 million | 0 | $0 |
| Cleveland Clinic Lerner Com-Cwru | Cleveland, OH | 5 | $5.4 million | 0 | $0 |
| Mayo Clinic Rochester | Rochester, MN | 3 | $5.4 million | 0 | $0 |
| University of California Los Angeles | Los Angeles, CA | 5 | $4.9 million | 0 | $0 |
| Indiana University Indianapolis | Indianapolis, IN | 4 | $4.7 million | 0 | $0 |
| University of Louisville | Louisville, KY | 2 | $4.7 million | 0 | $0 |
| Augusta University | Augusta, GA | 2 | $4.4 million | 0 | $0 |
| University of Chicago | Chicago, IL | 6 | $4.2 million | 0 | $0 |
| University of South Alabama | Mobile, AL | 8 | $4.1 million | 0 | $0 |
| Thomas Jefferson University | Philadelphia, PA | 2 | $4.1 million | 0 | $0 |
| Univ of Massachusetts Med SCH Worcester | Worcester, MA | 4 | $4 million | 0 | $0 |
| University of Kentucky | Lexington, KY | 4 | $4 million | 0 | $0 |
| Boston University Medical Campus | Boston, MA | 4 | $3.7 million | 0 | $0 |
| Biomembretics, Inc. | Scituate, MA | 1 | $3.2 million | 0 | $0 |
| Cedars-Sinai Medical Center | Los Angeles, CA | 2 | $3.2 million | 0 | $0 |
| Virginia Commonwealth University | Richmond, VA | 3 | $3.1 million | 0 | $0 |
| Venatorx Pharmaceuticals, Inc. | Malvern, PA | 1 | $3 million | 0 | $0 |
| Medical University of South Carolina | Charleston, SC | 2 | $3 million | 0 | $0 |
| University of Vermont & ST Agric College | Burlington, VT | 2 | $2.8 million | 0 | $0 |
| Feinstein Institute for Medical Research | Manhasset, NY | 2 | $2.8 million | 0 | $0 |
| University of Minnesota | Minneapolis, MN | 2 | $2.8 million | 0 | $0 |
| Cytoagents, Inc. | Pittsburgh, PA | 2 | $2.8 million | 0 | $0 |
| West Virginia University Research Corporation | Morgantown, WV | 1 | $2.8 million | 0 | $0 |
| Oregon Health & Science University | Portland, OR | 4 | $2.7 million | 0 | $0 |
| Icahn School of Medicine at Mount Sinai | New York, NY | 2 | $2.7 million | 0 | $0 |
| Illexcor Therapeutics, LLC | Richmond, VA | 2 | $2.7 million | 0 | $0 |
| University of Denver | Denver, CO | 1 | $2.6 million | 0 | $0 |
| University of Arizona | Tucson, AZ | 5 | $2.6 million | 0 | $0 |
| Cincinnati Childrens Hosp Med CTR | Cincinnati, OH | 3 | $2.6 million | 0 | $0 |
| Case Western Reserve University | Cleveland, OH | 1 | $2.6 million | 0 | $0 |
| Baylor College of Medicine | Houston, TX | 5 | $2.5 million | 0 | $0 |
| Brigham and Women's Hospital | Boston, MA | 3 | $2.5 million | 0 | $0 |
| Safebvm Corp. | Boston, MA | 2 | $2.5 million | 0 | $0 |
| University of California-Irvine | Irvine, CA | 2 | $2.5 million | 0 | $0 |
| Ceria Therapeutics, Inc. | Tucson, AZ | 2 | $2.3 million | 0 | $0 |
| Benaroya Research Inst at Virginia Mason | Seattle, WA | 1 | $2.3 million | 0 | $0 |
| CMTX Biotech, Inc. | Kings Park, NY | 3 | $2.2 million | 0 | $0 |
| Research Inst of Fox Chase Can CTR | Philadelphia, PA | 1 | $2.2 million | 0 | $0 |
| University of Virginia | Charlottesville, VA | 2 | $2.2 million | 0 | $0 |
| Versiti Blood Health, Inc. | Milwaukee, WI | 1 | $2.1 million | 0 | $0 |
| University of Wisconsin-Madison | Madison, WI | 1 | $2.1 million | 0 | $0 |
| Boston Children's Hospital | Boston, MA | 4 | $2 million | 0 | $0 |
| Rise Therapeutics, LLC | Rockville, MD | 1 | $2 million | 0 | $0 |
| Cartesian Therapeutics, Inc. | Gaithersburg, MD | 1 | $2 million | 0 | $0 |
| Dupage Medical Technology, Inc. | Chicago, IL | 1 | $2 million | 0 | $0 |
| Pharmain Corporation | Bothell, WA | 1 | $2 million | 0 | $0 |
| Xoran Technologies, LLC | Ann Arbor, MI | 1 | $2 million | 0 | $0 |
| University of Colorado at Boulder | Boulder, CO | 1 | $1.9 million | 0 | $0 |
| Texas A&M University | College Station, TX | 1 | $1.8 million | 0 | $0 |
| University of Cincinnati | Cincinnati, OH | 2 | $1.7 million | 0 | $0 |
| Florida International University | Miami, FL | 3 | $1.7 million | 0 | $0 |
| Massachusetts Institute of Technology | Cambridge, MA | 2 | $1.6 million | 0 | $0 |
| University Health Network | Toronto | 1 | $1.6 million | 0 | $0 |
| University of Florida | Gainesville, FL | 3 | $1.4 million | 0 | $0 |
| Saint Louis University | Saint Louis, MO | 2 | $1.4 million | 0 | $0 |
| Loyola University Chicago | Maywood, IL | 1 | $1.4 million | 0 | $0 |
| Harvard Medical School | Boston, MA | 1 | $1.4 million | 0 | $0 |
| Endeavor Health Clinical Operations | Evanston, IL | 1 | $1.4 million | 0 | $0 |
| SUNY at Buffalo | Amherst, NY | 1 | $1.3 million | 0 | $0 |
| Sigmovir Biosystems, Inc. | Rockville, MD | 2 | $1.2 million | 0 | $0 |
| University of Illinois at Urbana-Champaign | Urbana, IL | 1 | $1.1 million | 0 | $0 |
| Ihc Health Services, Inc. | Salt Lake City, UT | 1 | $1.1 million | 0 | $0 |
| University of Utah | Salt Lake City, UT | 4 | $1.1 million | 0 | $0 |
| Stevens Institute of Technology | Hoboken, NJ | 2 | $1 million | 0 | $0 |
| Xfibra, Inc. | Del Mar, CA | 1 | $999,601 | 0 | $0 |
| Fred Hutchinson Cancer Research Center | Seattle, WA | 2 | $956,684 | 0 | $0 |
| University of South Carolina at Columbia | Columbia, SC | 3 | $955,037 | 0 | $0 |
Funding by fiscal year
| Fiscal year | NIH awards | NIH amount | NSF awards | NSF amount |
|---|---|---|---|---|
| 2025 | 275 | $155,397,483 | 0 | $0 |
| 2024 | 263 | $138,679,640 | 0 | $0 |
| 2023 | 284 | $138,094,943 | 0 | $0 |
| 2022 | 279 | $124,617,173 | 0 | $0 |
| 2021 | 276 | $122,528,849 | 0 | $0 |
Open federal funding opportunities
From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.
Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.