| Rochester Area Community Foundation | 501(c)(3) | 1972 | $64.8 million | $510.7 million | 2025-03 |
| United Way of Greater Rochester and the Finger Lakes Inc | 501(c)(3) | 1987 | $31.8 million | $183.2 million | 2025-03 |
| Jewish Community Federation of Greater Rochester Ny Inc | 501(c)(3) | 1963 | $10.1 million | $52.8 million | 2025-06 |
| Sands Family Supporting Foundation Inc | 501(c)(3) | 2016 | $6.4 million | $110.2 million | 2025-03 |
| Jewish Senior Life Foundation Inc | 501(c)(3) | 1979 | $6.1 million | $63.9 million | 2024-12 |
| Golisano Autism Center Inc | 501(c)(3) | 2019 | $5 million | $10.3 million | 2024-12 |
| Rochester Area Community Foundation Depository Inc | 501(c)(3) | 1991 | $3.8 million | $5.4 million | 2025-03 |
| Al Sigl Foundation Inc | 501(c)(3) | 1998 | $3.3 million | $36.1 million | 2024-12 |
| Education Success Network Inc | 501(c)(3) | 2007 | $2.8 million | $6.4 million | 2025-06 |
| Rochester Area Community Foundation Initiatives Inc | 501(c)(3) | 2002 | $2.8 million | $1.5 million | 2025-03 |
| Wegmans Family Foundation Inc | 501(c)(3) | 2023 | $2.2 million | $53.2 million | 2024-12 |
| Temple Brith Kodesh Foundation | 501(c)(3) | 2007 | $1.2 million | $3.2 million | 2025-06 |
| Endless Highway Inc | 501(c)(3) | 2011 | $564,380 | $386,352 | 2025-12 |
| Uwgr Holding Company Inc | 501(c)(3) | 1998 | $384,924 | $2 million | 2025-03 |
| Rehema Home Us Fundraising Inc | 501(c)(3) | 2007 | $337,536 | $76,671 | 2025-12 |
| T Franklin Williams MD Foundation Inc | 501(c)(3) | 1991 | $290,421 | $1.1 million | 2024-12 |
| St Anns of Greater Rochester Inc | 501(c)(3) | 1996 | $224,599 | $4 million | 2024-12 |
| Rochester Area Foundation | 501(c)(3) | 1998 | $173,000 | $420,127 | 2025-03 |
| Ann Lib and Bernard Kozel Family Foundation | 501(c)(3) | 1997 | $127,177 | $2.1 million | 2025-06 |
| Venture Jobs Foundation Inc | 501(c)(3) | 2011 | $125,689 | $649,417 | 2024-12 |
| Futerman Supporting Foundation Inc | 501(c)(3) | 1997 | $89,277 | $481,198 | 2025-06 |
| Greater Rochester Eastern Area Tournament Inc | 501(c)(3) | 2024 | $48,515 | $13,848 | 2026-06 |
| Operation Patriot Foundation Inc | 501(c)(3) | 2006 | $48,332 | $7,725 | 2025-12 |
| United Way Services Corporation | 501(c)(3) | 1976 | $38,935 | $73,689 | 2025-08 |
| Rochester Press-Radio Charity Fund Inc | 501(c)(3) | 1967 | $38,866 | $79,956 | 2025-12 |
| Rada Charitable Foundation Inc | 501(c)(3) | 1985 | $38,400 | $6,548 | 2026-03 |
| Rochester Regional Physician Assistant Association | 501(c)(3) | 2019 | $36,051 | $18,451 | 2025-06 |
| Farleys Friends Inc | 501(c)(3) | 2016 | $34,843 | $56,919 | 2025-12 |
| Kiwanis Club of Penfield-Perinton Townships Foundation Inc | 501(c)(3) | 2014 | $32,320 | $27,096 | 2024-09 |
| Ugly Disco Inc | 501(c)(3) | 2005 | $24,965 | $11,040 | 2025-12 |
| Gates Chili Chamber of Commerce Foundation Inc | 501(c)(3) | 2023 | $20,370 | $683 | 2024-12 |
| Cortland and Ella Brovitzsupporting Foundation Inc | 501(c)(3) | 2007 | $19,898 | $916,896 | 2025-06 |
| Pearls of Grace Charitable Foundation of Rochester | 501(c)(3) | 2022 | $9,813 | $10,463 | 2023-12 |
| Pathstone Foundation | 501(c)(3) | 2021 | $6,445 | $374,612 | 2025-09 |
| Rochester E-Nable Limited | 501(c)(3) | 2018 | $5,059 | $53,884 | 2025-12 |
| The Gutkin Family Foundation | 501(c)(3) | 1996 | $1,351 | $47,580 | 2025-06 |
| Novem Foundation Inc | 501(c)(3) | 2019 | $13 | $11,486 | 2025-12 |
| Academy of Health Science Foundation | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Allyns Creek Foundation Inc | 501(c)(3) | 2001 | | $1.2 million | 2025-12 |
| Ashley Family Foundation Inc | 501(c)(3) | 1997 | | $3.9 million | 2025-12 |
| Beneath the Wild Sky Foundation Inc | 501(c)(3) | 2026 | | | |
| Brighter Days Foundation | 501(c)(3) | 2008 | | $793,547 | 2024-12 |
| Building Brighter Days Foundation I NC | 501(c)(3) | 2008 | | $12.2 million | 2024-12 |
| Bulrush Foundation | 501(c)(3) | 1996 | | $566,209 | 2025-09 |
| Burundi Orphans Inc | 501(c)(3) | 2025 | | | |
| Carl Thomas Korpi Memorial Fund | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Carpenter Family Caritas Foundation | 501(c)(3) | 2008 | | $1.5 million | 2026-06 |
| Cooke Family Charitable Foundation Inc | 501(c)(3) | 2021 | | $296,164 | 2025-12 |
| Costanza Family Foundation | 501(c)(3) | 2000 | | $2.6 million | 2024-12 |
| Cotroneo Family Foundation | 501(c)(3) | 2017 | | $866,731 | 2025-12 |
| Council of Agency Executives Inc | 501(c)(3) | 2026 | | | |
| David T & Karen Della Penta Charitable Trust | 501(c)(3) | 2009 | | $1.6 million | 2025-12 |
| Deblinger Family Foundation Inc | 501(c)(3) | 2000 | | $2.6 million | 2025-06 |
| Dhagool Development Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Duda Family Foundation | 501(c)(3) | 2013 | | $5 million | 2025-12 |
| Elf Foundation | 501(c)(3) | 2001 | | $2.6 million | 2025-12 |
| Erwin and Gertrude Davenport Private Foundation | 501(c)(3) | 2009 | | $415,234 | 2025-12 |
| Esl Charitable Foundation Inc | 501(c)(3) | 2003 | | $122.1 million | 2025-12 |
| Fly Runway Heading Foundation Inc | 501(c)(3) | 2025 | | $1 | 2025-12 |
| Fournier Family Charitable Foundation | 501(c)(3) | 2024 | | $1.7 million | 2025-11 |
| Gates-Chili Community Connections Corporation | 501(c)(3) | 2011 | $0 | $0 | 2026-06 |
| George D and Frieda B Abraham Foundation | 501(c)(3) | 2008 | | $17,017 | 2025-12 |
| Gloria Foundation | 501(c)(3) | 2025 | | | |
| Greater Rochester Health Foundation | 501(c)(3) | 2005 | | $273.8 million | 2024-12 |
| Guido and Ellen Palma Foundation Inc | 501(c)(3) | 1999 | | $1 million | 2025-09 |
| Handel Family Foundation | 501(c)(3) | 2021 | | $1.7 million | 2025-12 |
| Hasman Family Foundation | 501(c)(3) | 2024 | | $223,116 | 2025-12 |
| Hattie Harris Foundation | 501(c)(3) | 2000 | $0 | $0 | 2025-12 |
| Helping Community Charities | 501(c)(3) | 2000 | | $2,350 | 2025-12 |
| Human Betterment Project Inc | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Hurlbut Foundation | 501(c)(3) | 1995 | | $212,170 | 2025-06 |
| Irondequoit Rotary Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| James & Mary Ann Philippone Charitable Foundation Inc | 501(c)(3) | 2019 | | $1 | 2025-12 |
| Jane L Glazer and Laurence C Glazer Charitable Trust | 501(c)(3) | 2025 | | $6,683 | 2024-12 |
| Jeffery and Patricia Davis Family Foundation Inc | 501(c)(3) | 2015 | | $1.7 million | 2026-06 |
| Jkexec Foundation Inc | 501(c)(3) | 2026 | | | |
| John L Dimarco Sr Charitable Foundation | 501(c)(3) | 2016 | | $8.6 million | 2024-12 |
| KMT Foundation Inc | 501(c)(3) | 2022 | | $2.4 million | 2024-12 |
| Kathryn J & Theodore E Nixon Family Foundation Inc | 501(c)(3) | 2002 | | $121,914 | 2025-12 |
| Kiwanis West Central of Rochester Foundation Inc | 501(c)(3) | 1999 | $0 | $0 | 2025-09 |
| Lampton Family Foundation Inc | 501(c)(3) | 2007 | | $1.6 million | 2025-09 |
| Lou Gramm Foundation LTD | 501(c)(3) | 2021 | | $2,372 | 2024-12 |
| Lucelia Foundation Inc | 501(c)(3) | 1998 | | $6.4 million | 2024-12 |
| MM Incubator Inc | 501(c)(3) | 2025 | | $1 | 2025-12 |
| Marie C and Joseph C Wilson Foundation Inc | 501(c)(3) | 2020 | | $18.1 million | 2024-12 |
| Mark Dillon Memorial Fund Corp | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Market Love Foundation | 501(c)(3) | 2026 | | | |
| Mashomack Foundation | 501(c)(3) | 1971 | | $1.4 million | 2025-11 |
| Master Kims Taekwondo Community Ser Vice Corps | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Max and Marian Farash Charitable Foundation | 501(c)(3) | 2014 | | $341.9 million | 2024-12 |
| Maya Spaull Johnsen Legacy Fund Inc | 501(c)(3) | 2023 | | $67,983 | 2024-12 |
| Michael and Deborah Gordon Charitable Foundation Inc | 501(c)(3) | 2018 | | $1.5 million | 2024-12 |
| Miller Funeral and Cremation Charitable Foundation Inc | 501(c)(3) | 2018 | | $9,041 | 2025-12 |
| Mucci Family Foundation | 501(c)(3) | 2024 | | $13.5 million | 2025-12 |
| Myron S and Helen K Silver Family Foundation | 501(c)(3) | 2010 | | $601,381 | 2025-12 |
| National Association of Charitable Gift Planners | 501(c)(3) | 1992 | $0 | $0 | 2025-12 |
| Ny-Ne States Conf Intl Association of Heat and Frost Insulators & Asbstss Center | 501(c)(3) | 2002 | $0 | $0 | 2024-12 |
| Olivieri Family Foundation Inc | 501(c)(3) | 2019 | | $3.6 million | 2025-12 |
| One Doyle Team Cares Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Polisseni Foundation Inc | 501(c)(3) | 2002 | | $4,314 | 2025-08 |
| Ralph and Eleanor Cantisano Family Foundation | 501(c)(3) | 2003 | | $121,113 | 2024-12 |
| Red Wings Community Foundation Inc | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Robert G & Florence E Vanduyn Charitable Foundation | 501(c)(3) | 2010 | | $1.5 million | 2025-12 |
| Robert Owen Lehman Foundation Inc | 501(c)(3) | 2015 | | $6.5 million | 2024-12 |
| Roc the Plate | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Romeo Family Charitable Foundation Inc | 501(c)(3) | 1997 | $0 | $3,380 | 2026-03 |
| Rothenberg Family Foundation Inc | 501(c)(3) | 1997 | | $967,281 | 2025-12 |
| Rubin Family Foundation | 501(c)(3) | 2007 | | $764,401 | 2025-12 |
| Settlement Houses of Rochester Foundation Inc | 501(c)(3) | 2016 | $0 | $274 | 2023-12 |
| Summers Foundation Inc | 501(c)(3) | 2015 | | $1.4 million | 2025-12 |
| The Chapman-Davenport Foundation Inc | 501(c)(3) | 2001 | | $314,203 | 2025-09 |
| The David and Lisa Henion Foundation | 501(c)(3) | 2026 | | | |
| The Randall M White & Susan Cady-Wh Ite Family Foundation LTD | 501(c)(3) | 2026 | | | |
| The@thomas F Judson Jr and Elisabeth W Judson Foundation | 501(c)(3) | 2000 | | $237,168 | 2025-12 |
| Tino and Family Foundation Inc | 501(c)(3) | 2025 | | $1 | 2025-12 |
| Tones Family Foundation Inc | 501(c)(3) | 2019 | | $12,665 | 2025-12 |
| Tony DS T I E Take It Ease Charities Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Tucker Gosnell Family Foundation | 501(c)(3) | 2002 | | $4.2 million | 2024-12 |
| Turula Family Fund Inc | 501(c)(3) | 1999 | | $549,851 | 2025-12 |
| University Preparatory Charter School for Young Men Foundation in | 501(c)(3) | 2023 | $0 | $0 | 2026-06 |
| Wan Jou Family Foundation | 501(c)(3) | 2005 | | $914,424 | 2025-12 |
| Weller Family Foundation Inc | 501(c)(3) | 2006 | | $3.3 million | 2025-09 |
| William G McGowan Charitable Founda Tion of New York and Colorado Inc | 501(c)(3) | 2026 | | | |
| Williams Family Foundation Inc | 501(c)(3) | 1998 | | $645,251 | 2025-12 |