| Pathstone Corporation | 501(c)(3) | 1982 | $51 million | $62.3 million | 2025-09 |
| GRHS Foundation Inc | 501(c)(3) | 1995 | $44.3 million | $139.5 million | 2024-12 |
| Connected Communities Inc | 501(c)(3) | 2016 | $4.3 million | $4.4 million | 2024-12 |
| Greater Rochester Chamber of Commerce Inc | 501(c)(6) | 2006 | $4.2 million | $13.7 million | 2025-12 |
| Rochester Downtown Development Corporation | 501(c)(3) | 2016 | $2.7 million | $3.6 million | 2024-12 |
| Roc2025 Inc | 501(c)(6) | 2020 | $2.4 million | $1.4 million | 2025-12 |
| Greater Rochester Enterprise Inc | 501(c)(6) | 2002 | $2.4 million | $868,290 | 2025-12 |
| Greater Rochester Association of Realtors Inc | 501(c)(6) | 2000 | $2.2 million | $2.7 million | 2024-12 |
| Greater Rochester Enterprise Foundation Inc | 501(c)(3) | 2002 | $1.9 million | $233,975 | 2025-12 |
| Rochester Land Bank Corporation | 501(c)(3) | 2015 | $1.5 million | $3.4 million | 2025-06 |
| Excell Partners Inc | 501(c)(3) | 2017 | $1.4 million | $5.5 million | 2025-06 |
| Rochester Hope Inc | 501(c)(3) | 2023 | $1.2 million | $968,255 | 2025-12 |
| Rochester Automobile Dealers Association Inc | 501(c)(6) | 2007 | $1.1 million | $3 million | 2025-12 |
| New York State Brewers Association Inc | 501(c)(6) | 2005 | $974,693 | $764,428 | 2025-02 |
| Association of Convention & Visitors Bureau of New York State | 501(c)(6) | 2000 | $906,800 | $88,546 | 2025-12 |
| Shore Foundation | 501(c)(3) | 2018 | $701,590 | $267,835 | 2024-12 |
| Rochester Economic Development Corporation | 501(c)(3) | 1985 | $651,774 | $12.2 million | 2024-09 |
| Upstate United Inc | 501(c)(6) | 2014 | $560,230 | $159,105 | 2024-12 |
| South East Area Coalition Inc | 501(c)(3) | 1973 | $532,799 | $334,265 | 2025-06 |
| Tiuny Holdings Inc | 501(c)(2) | 2024 | $416,160 | $4.8 million | 2025-06 |
| Taproot Collective Inc | 501(c)(3) | 2017 | $411,243 | $176,135 | 2024-12 |
| National Payroll Reporting Consortium | 501(c)(6) | 2000 | $340,713 | $508,918 | 2024-12 |
| Wine Water and Wonders | 501(c)(6) | 2019 | $292,871 | $81,648 | 2025-12 |
| NCS Community Development Corp | 501(c)(3) | 1969 | $251,583 | $220,246 | 2025-06 |
| Rotary International | 501(c)(4) | 1942 | $246,305 | $61,453 | 2025-06 |
| Coalition of North East Associations Inc | 501(c)(3) | 1987 | $198,294 | $32,362 | 2025-06 |
| Dimensional Metrology Standards Consortium Inc | 501(c)(6) | 2005 | $197,391 | $313,628 | 2025-12 |
| Prosperrochester | 501(c)(3) | 2014 | $187,817 | $12,405 | 2025-12 |
| National Human Resources Association Inc | 501(c)(6) | 2004 | $135,765 | $54,535 | 2025-06 |
| Gamma Iota Boule Foundation Inc | 501(c)(3) | 2017 | $118,645 | $362,482 | 2024-12 |
| Rochester Police Foundation Inc | 501(c)(3) | 2014 | $117,858 | $729,344 | 2024-12 |
| Monroe County Family Coalition Inc | 501(c)(3) | 2021 | $111,247 | $20,913 | 2025-06 |
| Techrochester Inc | 501(c)(6) | 2002 | $109,911 | $55,588 | 2024-12 |
| Junior League of Rochester Inc | 501(c)(3) | 1944 | $107,268 | $444,689 | 2025-05 |
| 19TH Ward Community Association of Rochester New York Inc | 501(c)(3) | 1968 | $99,129 | $229,408 | 2023-12 |
| Rochester Greenovation Inc | 501(c)(3) | 2012 | $95,875 | $34,432 | 2024-12 |
| Gerhardt Neighborhood Outreach Center Inc | 501(c)(3) | 2007 | $91,900 | $136,422 | 2025-12 |
| Rochester Regional Photonics Cluster | 501(c)(6) | 2000 | $89,881 | $111,070 | 2024-12 |
| Downtown Special Services Incp Inc | 501(c)(3) | 2022 | $84,024 | $1,023 | 2025-06 |
| Western New York Chapter of the Association for Bridge | 501(c)(6) | 1999 | $80,981 | $76,245 | 2026-05 |
| Bloom Roc Inc | 501(c)(3) | 2024 | $80,453 | $2,068 | 2025-12 |
| Rise Up Rochester Incorporated | 501(c)(3) | 2000 | $61,847 | $40,881 | 2024-12 |
| Payroll Fraud Prevention Group Inc | 501(c)(6) | 2010 | $59,500 | $38,154 | 2025-12 |
| New York State Building Officials Conference Inc | 501(c)(6) | 2013 | $56,039 | $163,868 | 2025-12 |
| Rochester Alliance of Communities Transforming Society Inc | 501(c)(3) | 2015 | $47,145 | $12,972 | 2024-12 |
| Monroe Professional Engineers Society | 501(c)(6) | 2009 | $33,379 | $43,298 | 2026-06 |
| Apollos Aim Inc | 501(c)(3) | 2026 | $28,057 | $3,126 | 2025-12 |
| Greece Chamber Charitable Foundation Inc | 501(c)(3) | 2002 | $23,582 | $37,727 | 2024-12 |
| National Council of Jewish Women Incorporated | 501(c)(3) | 1949 | $13,045 | $83,365 | 2025-06 |
| Hinge Neighbors Inc | 501(c)(3) | 2019 | $9,339 | $40,500 | 2025-06 |
| Gates-Chili Chamber of Commerce Inc | 501(c)(6) | 2008 | $9,190 | $20,930 | 2024-12 |
| South Wedge Area Neighborhood Council Inc | 501(c)(3) | 2012 | $8,900 | $1,162 | 2025-06 |
| Realtors Charitable Foundation | 501(c)(3) | 2002 | $3,350 | $6,724 | 2024-12 |
| Aenon Community Development Inc | 501(c)(3) | 2024 | $1,780 | $1,645 | 2025-12 |
| Southwest Rochester Kiwanis Foundat Ion Inc | 501(c)(3) | 2026 | $1,180 | $74,203 | 2020-12 |
| Rochester Association of Black Journalists Inc | 501(c)(3) | 2018 | $217 | $6,863 | 2025-12 |
| Defense Industries Network Inc | 501(c)(6) | 2021 | $19 | $4,209 | 2025-12 |
| 1deed Inc | 501(c)(3) | 2024 | | | |
| 490 Farmers Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Abc Streets Neighborhood Association Inc | 501(c)(4) | 2014 | $0 | $0 | 2025-12 |
| Atlantic-Culver-East Main Neighborhood Association | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Bhutanese Community of Greater Rochester Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Black Business Directory Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-09 |
| Bridges for Better Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Burch Community Foundation Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| CDC of Upstate New York Inc | 501(c)(3) | 2016 | | $586,023 | 2025-12 |
| Cameroon Association of Greater Rochester Inc | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Carki Global Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Charlotte Community Association 23RD Ward Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Charlotte Community Development Corporation | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Culver Merchants Business Association Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Design Build Institute of America | 501(c)(6) | 2000 | $0 | $0 | 2025-12 |
| Digital Game Industry Association of Rochester Incorporated | 501(c)(6) | 2021 | $0 | $0 | 2025-12 |
| Drive To Read Inc | 501(c)(3) | 2022 | $0 | $0 | 2023-12 |
| Empire Zone of Monroe County Inc | 501(c)(3) | 2004 | | | |
| Endow Foundaton Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| FTS Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Family Restoration Project Inc | 501(c)(3) | 1996 | $0 | $0 | 2025-12 |
| Finger Lakes Organization of Nurse Executives Inc | 501(c)(6) | 2010 | $0 | $0 | 2025-12 |
| Foundation of the Rochester Latino Rotary Club | 501(c)(3) | 2014 | $0 | $0 | 2025-06 |
| GWM Fresh Start Corp | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Gates Brighter Days Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2026-06 |
| Gather Our Collective Healing Inc | 501(c)(3) | 2024 | $0 | $0 | 2026-01 |
| Generational Engagement Matters | 501(c)(3) | 2022 | | $1 | 2025-05 |
| Genesee Impact Ventures Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Greece Economic Development Projects Inc | 501(c)(3) | 2003 | | | |
| Greece Ridge Lions Club | 501(c)(4) | 2019 | $0 | $0 | 2025-06 |
| Highland Park Neighborhood Association | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Indigenous Peoples Center Inc | 501(c)(3) | 2026 | | | |
| International Union United Auto Aer Ospace & Agricultural Workers of A | 501(c)(5) | 1941 | $0 | $0 | 2025-12 |
| Irondequoit Chamber of Commerce Inc | 501(c)(6) | 2012 | $0 | $0 | 2025-12 |
| Jay Foundation Inc | 501(c)(3) | 2008 | $0 | $0 | 2023-12 |
| Joseph Avenue Business Association | 501(c)(6) | 2013 | $0 | $0 | 2023-12 |
| Kiwanis Club of Greece Ny Foundation Inc | 501(c)(3) | 2013 | $0 | $0 | 2025-09 |
| Korean American Ophthalmology Society Inc | 501(c)(6) | 2011 | $0 | $0 | 2025-12 |
| Laurelton Neighborhood Association | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Lyell Avenue Business Association | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Lyell Otis Community Association in C | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Maplewood Neighborhood Association of Rochester Inc | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Marine Corps League | 501(c)(4) | 1946 | $0 | $0 | 2025-06 |
| Market District Business Association of Rochester Ny | 501(c)(6) | 2020 | $0 | $0 | 2025-09 |
| Marketview Heights Collective Action Project Inc | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Martin Luther King Jr Greater Rochester Commission Inc | 501(c)(3) | 2024 | $0 | $0 | 2024-08 |
| Monroe Avenue Merchants Association Inc | 501(c)(6) | 2013 | $0 | $0 | 2025-12 |
| Monroe County Probation Officers Association Inc | 501(c)(6) | 2014 | $0 | $0 | 2025-12 |
| NW Neighborhood Out Reach Center Inc | 501(c)(3) | 1995 | $0 | $0 | 2024-06 |
| National Association of Postal Supervisors | 501(c)(5) | 2014 | $0 | $0 | 2024-12 |
| New Hope for Marketview Heights Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| New York-Israel Chamber of Commerce | 501(c)(6) | 2019 | $0 | $0 | 2023-12 |
| Niche Market Insights Foundation Inc | 501(c)(3) | 2021 | $0 | $6,124 | 2025-12 |
| North Star Commons Community Development Corporation | 501(c)(3) | 2003 | | | |
| Park Avenue Merchants Association | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Park Avenue Neighborhood Association | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Parkside Neighborhood Association | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Partners Advocating for Community Change Incorporated | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Pathstone Corporation | 501(c)(3) | 1982 | | | |
| Pathstone Corporation | 501(c)(3) | 1982 | | | |
| Pathstone Corporation | 501(c)(3) | 1982 | | | |
| Photonics Industry Association of New York Inc | 501(c)(6) | 1999 | $0 | $0 | 2025-09 |
| Plymouth-Exchange Neighborohood Association Inc | 501(c)(3) | 2015 | $0 | $0 | 2026-06 |
| Remember7loaves Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Respectandbekind Inc | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Rochester Angel Network Inc | 501(c)(6) | 2006 | $0 | $0 | 2025-12 |
| Rochester Area Business Ethicsfoundation | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Rochester Area Society of Health System Pharmacists | 501(c)(6) | 2003 | $0 | $0 | 2026-06 |
| Rochester Community Organization Corporation | 501(c)(3) | 2025 | | | |
| Rochester Deaf Rotary Inc | 501(c)(4) | 2022 | $0 | $0 | 2026-06 |
| Rochester Finger Lakes Dental Hygienists Association | 501(c)(6) | 2017 | $0 | $0 | 2025-12 |
| Rochester Professional Consultants Network Inc | 501(c)(3) | 2019 | $0 | $0 | 2026-06 |
| Rochester Roentgen Ray Society | 501(c)(6) | 2025 | | | |
| Rochester Travel Professionals Inc | 501(c)(6) | 2013 | $0 | $0 | 2025-12 |
| Rochester Young Professionals Inc | 501(c)(4) | 2025 | $0 | $0 | 2025-12 |
| Saving Aj Inc | 501(c)(3) | 2024 | | | |
| Sons of Padre Pio Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Southwest Area Development Corp | 501(c)(3) | 1998 | $0 | $0 | 2024-12 |
| St Paul Outreach Center Inc | 501(c)(3) | 2026 | | | |
| Streams in the Desert Inc | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Summerville White City Windsor and Beitry Beach Residents Association | 501(c)(3) | 2022 | $0 | $0 | 2023-12 |
| Trailblazers Foundation | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Turkmen Global Foundation Inc | 501(c)(3) | 2025 | $0 | $0 | 2026-01 |
| Upstate Building Industry Alliance | 501(c)(6) | 2016 | $0 | $0 | 2025-12 |
| Upstate New York Electronic Security Association Unyesa | 501(c)(6) | 2016 | $0 | $0 | 2025-12 |
| Washington Square Park Community Association Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Winona Woods Neighborhood Association Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Womens Council of Realtors | 501(c)(6) | 2010 | $0 | $0 | 2024-12 |
| Business Association of the South Wedge Area Inc | 501(c)(6) | 2006 | $-3,124 | $54,190 | 2025-06 |