Data / Nonprofits / Missouri / Sikeston
Nonprofits in Sikeston, MO: 138 registered with the IRS
138 nonprofits are registered with the IRS in Sikeston, MO, 108 of them 501(c)(3) charities; the 38 that report revenue took in $276.9 million. The largest by revenue: Missouri Delta Medical Center ($188.6 million), Delta Area Economic Opportunity Corporation ($30.5 million), Southeast Missouri Food Bank ($26.5 million). Most common causes: religion-related (17), education (12), human services (12).
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Every organization, largest by revenue first
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Missouri Delta Medical Center | Health care | 501(c)(3) | 1951 | $188.6 million | $99.4 million | 2025-09 |
| Delta Area Economic Opportunity Corporation | 501(c)(3) | 1966 | $30.5 million | $27.7 million | 2024-12 | |
| Southeast Missouri Food Bank | Food, agriculture and nutrition | 501(c)(3) | 1986 | $26.5 million | $20.8 million | 2024-12 |
| Bootheel Counseling Services | Mental health and crisis intervention | 501(c)(3) | 1976 | $13.1 million | $10.6 million | 2024-06 |
| Kenny Rogers Childrens Center | 501(c)(3) | 1986 | $2.5 million | $6.4 million | 2024-12 | |
| Sikeston Regional Chamber of Commerce Inc | Community improvement and capacity building | 501(c)(6) | 2019 | $2.3 million | $1.5 million | 2024-12 |
| Missouri Bootheel Regional Consortium Incorporated | Health care | 501(c)(3) | 2003 | $1.7 million | $531,841 | 2024-09 |
| YMCA of Southeast Missouri | Human services | 501(c)(3) | 1994 | $1.3 million | $6.7 million | 2024-12 |
| Knights of Columbus | 501(c)(8) | 1940 | $1.3 million | $4.9 million | 2025-12 | |
| Sikeston Public Schools Foundation | Education | 501(c)(3) | 2006 | $1.3 million | $3.2 million | 2025-06 |
| Missouri Delta Medical Center Foundation | 501(c)(3) | 1991 | $1.1 million | $6.3 million | 2025-09 | |
| Sikeston Jaycee Bootheel Rodeo Association Incorporated | 501(c)(4) | 1975 | $828,092 | $4.2 million | 2024-12 | |
| Mission Missouri | Food, agriculture and nutrition | 501(c)(3) | 1999 | $746,158 | $415,992 | 2025-12 |
| Scott County Transit System Inc | 501(c)(3) | 1984 | $516,805 | $281,259 | 2025-06 | |
| Sikeston Christian School | Education | 501(c)(3) | 2004 | $514,002 | $2 million | 2024-12 |
| Community Sheltered Workshop Inc | Employment | 501(c)(3) | 1971 | $511,010 | $1.5 million | 2025-06 |
| David Craig Ministries Inc | 501(c)(3) | 1981 | $492,080 | $4 million | 2026-03 | |
| House of Refuge for Battered and Abused Women | Human services | 501(c)(3) | 2000 | $425,968 | $654,051 | 2024-12 |
| Sikeston Area Economic Development Corporation | Community improvement and capacity building | 501(c)(6) | 2019 | $331,350 | $238,817 | 2024-12 |
| Benevolent and Protective Order of Elks of the USA | Mutual and membership benefit | 501(c)(8) | 1951 | $328,102 | $936,040 | 2026-03 |
| Fraternal Order of Eagles | 501(c)(8) | 1991 | $278,368 | $1.1 million | 2025-05 | |
| Spread Hope Now Inc | Human services | 501(c)(3) | 2015 | $256,808 | $443,275 | 2024-12 |
| Veterans of Foreign Wars Dept of | 501(c)(19) | 1967 | $236,284 | $332,399 | 2025-06 | |
| American Postal Workers Union | 501(c)(5) | 1973 | $224,985 | $546,333 | 2025-12 | |
| Southeast Missouri Christian Academy Inc | Education | 501(c)(3) | 2019 | $144,213 | $62,397 | 2025-07 |
| American Legion Auxiliary | 501(c)(19) | 1946 | $139,850 | $91,486 | 2024-12 | |
| Epsilon Iota of Pi Kappa Alpha Inc | Education | 501(c)(7) | 2017 | $133,540 | $35,241 | 2025-12 |
| American Legion Post 114 | Public and societal benefit | 501(c)(19) | 2025 | $128,110 | $405,326 | 2025-12 |
| Pregnancy Resource Center of Sikeston | Human services | 501(c)(3) | 2014 | $113,635 | $137,693 | 2025-07 |
| My Fathers House | Religion-related | 501(c)(3) | 2021 | $75,203 | $38,032 | 2025-12 |
| Historic Midtown Development Group | Community improvement and capacity building | 501(c)(3) | 2006 | $67,518 | $14,608 | 2024-12 |
| Semo Electric Foundation Inc | Education | 501(c)(3) | 2008 | $55,262 | $40,448 | 2025-12 |
| Rotary International | 501(c)(4) | 1966 | $50,335 | $13,082 | 2024-06 | |
| Sikeston Cultural Development | Arts, culture and humanities | 501(c)(3) | 1998 | $49,033 | $19,534 | 2024-12 |
| Sikeston-Bootheel Area United Way Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1981 | $34,217 | $31,294 | 2025-06 |
| International Association of Lions Clubs | 501(c)(4) | 1966 | $33,568 | $54,900 | 2025-06 | |
| Sikeston Little Theatre Inc | Arts, culture and humanities | 501(c)(3) | 1969 | $21,108 | $77,398 | 2025-06 |
| Robert Chase Rodgers Memorial Scholarship | Education | 501(c)(3) | 2024 | $1,325 | $425 | 2025-12 |
| Agape Love Kingdom Ministries | Religion-related | 501(c)(3) | 2010 | |||
| Allegro Music Club | Arts, culture and humanities | 501(c)(3) | 1997 | $0 | $0 | 2025-06 |
| Altrusa International Foundation Inc | Education | 501(c)(3) | 1985 | $0 | $0 | 2026-05 |
| Altrusa International Inc | 501(c)(4) | 1944 | $0 | $0 | 2026-05 | |
| Altrusa International Inc | 501(c)(4) | 1967 | $0 | $0 | 2025-05 | |
| Americare USA Employee Benevolence Trust | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Ancient Free & Accepted Masons of Missouri | 501(c)(10) | 1940 | $0 | $0 | 2025-12 | |
| Arise Ministries | Religion-related | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Arrows Christian Academy | Education | 501(c)(3) | 2024 | |||
| Association of Operating Room Nurses Inc | 501(c)(6) | 1969 | $0 | $0 | 2025-03 | |
| Bahais of Sikeston | 501(c)(3) | 1995 | ||||
| Bement Baptish Church Sikeston | 501(c)(3) | 1965 | ||||
| Bootheel Regional Board of Realtors Inc | Community improvement and capacity building | 501(c)(6) | 2019 | $0 | $0 | 2025-12 |
| Bowman Street Church of Christ | Religion-related | 501(c)(3) | 2026 | |||
| Brightlife Recovery Foundation Inc | Mental health and crisis intervention | 501(c)(3) | 2025 | |||
| CBC Family Life Outreach Center Inc | Recreation and sports | 501(c)(3) | 2009 | $0 | $0 | 2025-09 |
| Carl Hamilton Foundation | Public and societal benefit | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Comfort Cause of Se Missouri | Diseases, disorders and medical disciplines | 501(c)(3) | 2025 | |||
| Communities Loving and Supporting S Tudents | Human services | 501(c)(3) | 2026 | $0 | $0 | 2020-12 |
| Community Builders of Sikeston Inc | Housing and shelter | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Competent Care | Human services | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Concordia Lutheran Church | 501(c)(3) | 1941 | ||||
| Cornerstone Baptist Church of Sikeston Inc | Religion-related | 501(c)(3) | 1997 | |||
| Crossroads Hope Community Church Sikeston | 501(c)(3) | 1965 | ||||
| Daughters of Sunset | Human services | 501(c)(3) | 2007 | $0 | $0 | 2024-12 |
| Day 366 | Housing and shelter | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Delta Kappa Gamma Society International | 501(c)(6) | 1965 | $0 | $0 | 2026-06 | |
| Elite Heat Basketball | Recreation and sports | 501(c)(3) | 2024 | |||
| Executive Board of the Missouri Baptist Convention | 501(c)(3) | 1965 | ||||
| Farm Credit Southeast Missouri Flca | Public and societal benefit | 501(c)(1) | 2002 | |||
| First Assembly of God | 501(c)(3) | 1964 | ||||
| First Baptist Church | 501(c)(3) | 1965 | ||||
| First Baptist Church of Miner Missouri | 501(c)(3) | 1979 | ||||
| First Christian Church | 501(c)(3) | 1951 | ||||
| First United Methodist Church of Sikeston | 501(c)(3) | 1974 | 2011-12 | |||
| Fraternal Order of Eagles | Mutual and membership benefit | 501(c)(8) | 1991 | $0 | $0 | 2025-05 |
| Frontline Ministries of Sikeston in C | Religion-related | 501(c)(3) | 2026 | |||
| Glory of God Church of God in Christ | 501(c)(3) | 1969 | ||||
| Good Brother Ministry | Mental health and crisis intervention | 501(c)(3) | 2026 | |||
| Gospel Assembly Church | 501(c)(3) | 1987 | ||||
| Grace Tabernacle Cooljc | Religion-related | 501(c)(3) | 2014 | |||
| Greater Works Church of Jesus Christ Inc | 501(c)(3) | 1993 | ||||
| Heartland Advanced Practice Nurses Network | Education | 501(c)(3) | 2000 | $0 | $0 | 2025-12 |
| Highway Hero Honoree Scholarship | 501(c)(3) | 2018 | $10,398 | 2025-12 | ||
| I A M Research & Wellness Foundation | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| International Association of Sheet Metal Air Rail & Transportation | Employment | 501(c)(5) | 2015 | $0 | $0 | 2025-12 |
| Itm Foundation Inc | Recreation and sports | 501(c)(3) | 2026 | |||
| Its Time 2 Get Up Ministries Inc | Human services | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Kingdom Living Ministries Inc | Human services | 501(c)(3) | 1996 | |||
| Kings Way Christian Church | Religion-related | 501(c)(3) | 1996 | |||
| Kiwanis International Inc | 501(c)(4) | 1940 | $0 | $0 | 2024-09 | |
| Laundry Baskets Full of Love - Not for Profit | Human services | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Love and Lite Church Ministry Inc | 501(c)(3) | 1991 | ||||
| Mercy Foundation | Human services | 501(c)(3) | 2024 | |||
| Miner Baptist Church | 501(c)(3) | 1965 | ||||
| Missouri 911 Directors Association | Community improvement and capacity building | 501(c)(6) | 2010 | $0 | $0 | 2025-12 |
| Murray Lane Baptist Church | 501(c)(3) | 1965 | ||||
| New Deliverance Outreach Ministries Inc | Community improvement and capacity building | 501(c)(3) | 2025 | $0 | $0 | 2025-09 |
| New Direction Outreach Ministries | Religion-related | 501(c)(3) | 2009 | |||
| New Hope Ministries | Religion-related | 501(c)(3) | 2005 | |||
| North Acres Recreation Club Inc | 501(c)(7) | 1978 | $0 | $0 | 2025-12 | |
| Old Bethel Baptist Church | 501(c)(3) | 1965 | ||||
| One Church Upc Inc | Religion-related | 501(c)(3) | 2004 | |||
| Open Door Fellowship Outreach Inc | Religion-related | 501(c)(3) | 2012 | |||
| Paris Outreach Ministries Inc | Youth development | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Parker Memorial Pentecostal Holines Holiness Church | 501(c)(3) | 1964 | ||||
| Place of Peace | Education | 501(c)(3) | 2005 | |||
| Redeeming Works | Environment | 501(c)(3) | 2026 | |||
| Rehoboth Center Inc | Human services | 501(c)(3) | 2024 | |||
| Ron Shum Evangelistic Association | Religion-related | 501(c)(3) | 2007 | $0 | $0 | 2023-12 |
| Rose of Sharon Chapter 4 Order of E Astern Star-Mo | Public and societal benefit | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| SHRM of Southeast Missouri | Employment | 501(c)(6) | 2012 | $0 | $0 | 2025-12 |
| Scott County Backstoppers | Public safety, disaster preparedness and relief | 501(c)(3) | 2025 | |||
| Scott County Central All Schools Foundation | Education | 501(c)(3) | 2015 | $0 | $0 | 2026-06 |
| Second Half Church Inc | Religion-related | 501(c)(3) | 2021 | |||
| Sikeston Bulldog Booster Club Inc | 501(c)(3) | 1990 | $0 | $0 | 2025-12 | |
| Sikeston Economic Development Corporation | Community improvement and capacity building | 501(c)(6) | 2011 | $0 | $1 | 2025-06 |
| Sikeston Little League Inc | 501(c)(3) | 1994 | $0 | $0 | 2025-12 | |
| Sikeston Parks and Recreation Foundation | Recreation and sports | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Sikeston Rodeo Museum | Arts, culture and humanities | 501(c)(3) | 2024 | |||
| Sikeston Veterans Park | Public and societal benefit | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Sikeston Youth Soccer League Incorporated | Youth development | 501(c)(3) | 1996 | $0 | $0 | 2026-06 |
| Southeast Elementary Pto | Education | 501(c)(3) | 2024 | $0 | $0 | 2024-06 |
| Southeast Missouri Challenger Baseball Inc | Recreation and sports | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Southeast Missouri Recovery Alliance | Mental health and crisis intervention | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Southeast Missouri Rural Minority Health Coalition Inc | Community improvement and capacity building | 501(c)(3) | 2015 | $0 | $48,616 | 2024-12 |
| St John Missionary Baptist Church | 501(c)(3) | 1985 | ||||
| St Pauls Episcopal Church | 501(c)(3) | 1971 | ||||
| Strength Through Resilience Integrity Perserverance and Empowe | Recreation and sports | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Sunset Community Housing Partnership | Housing and shelter | 501(c)(3) | 2025 | |||
| Tanner St Church of God | 501(c)(3) | 1960 | ||||
| Terra Nova | Religion-related | 501(c)(3) | 2013 | |||
| Toastmasters International | 501(c)(3) | 1945 | $0 | $0 | 2023-12 | |
| Total Health Environment Group Inc | 501(c)(3) | 1988 | $0 | $0 | 2025-12 | |
| Trinity Gospel Church | Religion-related | 501(c)(3) | 1997 | |||
| United States Bowling Congress Inc | Recreation and sports | 501(c)(3) | 2004 | $0 | $0 | 2026-07 |
| United Steelworkers | 501(c)(5) | 1940 | $0 | $0 | 2025-12 | |
| VFW Auxiliary Department of Missouri | 501(c)(4) | 1970 | $0 | $0 | 2025-06 | |
| VFW Auxiliary Department of Missouri | 501(c)(4) | 1970 | $0 | $0 | 2026-06 | |
| World Overcomers Worship Ministries | Religion-related | 501(c)(3) | 2026 |
By cause in Sikeston, MO
- Religion-related 17
- Education 12
- Human services 12
- Community improvement and capacity building 8
- Recreation and sports 7
- Public and societal benefit 5
- Arts, culture and humanities 5
- Mental health and crisis intervention 4
- Housing and shelter 3
- Employment 3
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.