Data / Nonprofits / Missouri / Saint Louis
Nonprofits in Saint Louis, MO: 9,221 registered with the IRS
9,221 nonprofits are registered with the IRS in Saint Louis, MO, 7,958 of them 501(c)(3) charities; the 2,048 that report revenue took in $58.50 billion. The largest by revenue: BJC Health System ($11.25 billion), Ascension Seton ($3.32 billion), Ascension Health Alliance ($3.28 billion). Most common causes: philanthropy, voluntarism and grantmaking foundations (1,432), education (770), human services (608).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| BJC Health System | Health care | 501(c)(3) | 2002 | $11.25 billion | $7.98 billion | 2024-12 |
| Ascension Seton | 501(c)(3) | 2009 | $3.32 billion | $3.39 billion | 2025-06 | |
| Ascension Health Alliance | 501(c)(3) | 1946 | $3.28 billion | $22.16 billion | 2025-06 | |
| SSM Health Care St Louis | Health care | 501(c)(3) | 1946 | $2.19 billion | $1.08 billion | 2024-12 |
| BJC Health System | Health care | 501(c)(3) | 2002 | $2.04 billion | $7.79 billion | 2024-12 |
| Sacred Heart Health System Inc | Health care | 501(c)(3) | 1946 | $1.85 billion | $939 million | 2025-06 |
| St Vincent Hospital & Health Care | Health care | 501(c)(3) | 1946 | $1.66 billion | $1.25 billion | 2025-06 |
| SSM Health Care Corporation | Health care | 501(c)(3) | 1946 | $1.39 billion | $7.02 billion | 2024-12 |
| Saint Thomas West Hospital | Health care | 501(c)(3) | 1946 | $1.27 billion | $763.8 million | 2025-06 |
| St Louis University | Education | 501(c)(3) | 1946 | $1.20 billion | $3.05 billion | 2025-06 |
| SSM Health Care of Oklahoma Inc | Health care | 501(c)(3) | 1946 | $1.12 billion | $453.7 million | 2024-12 |
| Ascension Health-Is Inc | 501(c)(3) | 1946 | $989.7 million | $739.1 million | 2025-06 | |
| Ssm-Sluh Inc | 501(c)(3) | 1946 | $947.9 million | $708.1 million | 2024-12 | |
| Ascension Via Christi Hospitals Wichita Inc | Health care | 501(c)(3) | $844.6 million | $391 million | 2025-06 | |
| SSM Health Care of Wisconsin Inc | Health care | 501(c)(3) | 1946 | $770.2 million | $499.4 million | 2024-12 |
| Columbia St Marys Hospital Milwaukee Inc | Health care | 501(c)(3) | 1946 | $724 million | $455.9 million | 2025-06 |
| Mercy Hospital South | Health care | 501(c)(3) | 1996 | $709.1 million | $539.4 million | 2025-06 |
| St Marys Health Inc Dba Ascension | Health care | 501(c)(3) | 1946 | $669.3 million | $369.9 million | 2025-06 |
| Agnesian Healthcare Inc | Health care | 501(c)(3) | 1946 | $584.4 million | $743.4 million | 2024-12 |
| Presence Chicago Hospitals Network | Human services | 501(c)(3) | 1943 | $562.3 million | $293 million | 2025-06 |
| St Agnes Healthcare Inc | Health care | 501(c)(3) | 1946 | $536.7 million | $364.5 million | 2025-06 |
| Saint Thomas Rutherford Hospital | Health care | 501(c)(3) | 1946 | $519.8 million | $434.5 million | 2025-06 |
| St Vincents Medical Center Inc | 501(c)(3) | 1946 | $493 million | $312.6 million | 2025-06 | |
| Beacon Kalamazoo Inc | Health care | 501(c)(3) | 2026 | $486.2 million | $220.6 million | 2025-06 |
| Alexian Brothers Medical Center | Health care | 501(c)(3) | 1946 | $475.1 million | $323.3 million | 2025-06 |
| SSM Cardinal Glennon Childrens Hospital | Health care | 501(c)(3) | 1946 | $441.3 million | $602.9 million | 2024-12 |
| Ascension Se Wisconsin Hospital Inc | Health care | 501(c)(3) | 1946 | $400.5 million | $277.7 million | 2025-06 |
| St Alexius Medical Center | Health care | 501(c)(3) | 1946 | $389.3 million | $244.3 million | 2025-06 |
| Ascension Health | Health care | 501(c)(3) | 1946 | $383.1 million | $2.17 billion | 2025-06 |
| Saint Thomas Medical Partners | Health care | 501(c)(3) | 1997 | $366.2 million | $125.3 million | 2025-06 |
| Ascension Providence | Health care | 501(c)(3) | 1946 | $357.5 million | $206.1 million | 2025-06 |
| St Lukes - St Vincents Healthcareinc | Health care | 501(c)(3) | 1946 | $355.2 million | $210 million | 2025-06 |
| Ascension All Saints Hospital Inc | Health care | 501(c)(3) | 1946 | $355 million | $271.1 million | 2025-06 |
| SSM Health Care Group | Health care | 501(c)(3) | 2022 | $351.9 million | $175.8 million | 2024-12 |
| St Vincent Medical Group Inc | 501(c)(3) | 1946 | $338.6 million | $158.4 million | 2025-06 | |
| St Vincent Carmel Hospital Inc | 501(c)(3) | 1946 | $290.9 million | $167.6 million | 2025-06 | |
| Ascension Health Professional and General Liability Self-Insurance | Mutual and membership benefit | 501(c)(3) | 2006 | $286 million | $711.6 million | 2025-06 |
| Concordia Health Plan | 501(c)(9) | 1966 | $285.8 million | $215.8 million | 2024-12 | |
| Seton Family of Doctors | Health care | 501(c)(3) | 2014 | $284.3 million | $207.3 million | 2025-06 |
| SSM Health Businesses | Health care | 501(c)(3) | 1946 | $273.9 million | $284.6 million | 2024-12 |
| Good Samaritan Regional Health Center | Health care | 501(c)(3) | 1999 | $264.5 million | $169.9 million | 2024-12 |
| Stifel Charitable Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $261.5 million | $733.3 million | 2025-12 |
| Presence St Marys Hospital Presence Central and Suburban Hospitals Net | Health care | 501(c)(3) | 1946 | $256 million | $161.2 million | 2025-06 |
| Lutheran Senior Services | Human services | 501(c)(3) | 1946 | $254.5 million | $898.9 million | 2024-12 |
| Mers Missouri Goodwill Industries | Human services | 501(c)(3) | 1938 | $251.7 million | $177.3 million | 2024-12 |
| The Monroe Clinic Inc | Health care | 501(c)(3) | 1946 | $237.1 million | $310.4 million | 2024-12 |
| Ascension Medical Group-Southeast Wisconsin Inc | Health care | 501(c)(3) | 1946 | $235.8 million | $64.8 million | 2025-06 |
| Dell Childrens Medical Group | Health care | 501(c)(3) | 2014 | $208.3 million | $38.9 million | 2025-06 |
| St Anthony Shawnee Hospital Inc | Health care | 501(c)(3) | 1946 | $205.5 million | $146.6 million | 2024-12 |
| Ascension Health Texas | Health care | 501(c)(3) | 1946 | $202.8 million | $110.1 million | 2025-06 |
| St Vincent Anderson Regional Hospital Inc | Health care | 501(c)(3) | 1946 | $192.6 million | $92.4 million | 2025-06 |
| Ascension Welfare Benefits Trust | Mutual and membership benefit | 501(c)(9) | 2001 | $191.4 million | $172.4 million | 2024-12 |
| Ascension Wisconsin Inc | Health care | 501(c)(3) | 2001 | $183.1 million | $229.7 million | 2025-06 |
| Maryville University of St Louis | Education | 501(c)(3) | 1980 | $171.7 million | $286.7 million | 2025-05 |
| St Vincents Health System Inc | Health care | 501(c)(3) | 1946 | $168.7 million | $231.8 million | 2025-06 |
| Webster University | Education | 501(c)(3) | 1970 | $166.6 million | $284 million | 2025-05 |
| Ameren Active Employee Healthcare Trust | Mutual and membership benefit | 501(c)(9) | 2023 | $164.6 million | $15.4 million | 2024-12 |
| Acension St Vincent South Side | 501(c)(3) | 1946 | $163.9 million | $111.2 million | 2025-06 | |
| St Louis Childrens Hospital Foundation | Health care | 501(c)(3) | 1994 | $159.1 million | $631.7 million | 2024-12 |
| Principia Corporation | Education | 501(c)(3) | 1951 | $158.2 million | $1.29 billion | 2025-06 |
| SSM Regional Health Services | Health care | 501(c)(3) | 1946 | $147.3 million | $69.8 million | 2024-12 |
| St Louis Community Foundation Incorporated | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1996 | $146.3 million | $494.4 million | 2024-12 |
| Jane Phillips Memorial Medical Center Inc | Health care | 501(c)(3) | 1954 | $144.8 million | $64.8 million | 2025-06 |
| St Vincent Health Inc | Health care | 501(c)(3) | 1999 | $131.4 million | $93.2 million | 2025-06 |
| Alexian Brothers Health System | Health care | 501(c)(3) | 1946 | $130.2 million | $132.5 million | 2025-06 |
| Ascension St Francis Hospital Inc | Health care | 501(c)(3) | 1946 | $128.4 million | $56.3 million | 2025-06 |
| Central Indiana Health System Cardiac Services Inc | 501(c)(3) | 1993 | $128.2 million | $795.9 million | 2025-06 | |
| St Marys Hospital | Health care | 501(c)(3) | 1946 | $123.8 million | $128.3 million | 2024-12 |
| Ascension Medical Group-Fox Valley Wisconsin Inc | Health care | 501(c)(3) | 1999 | $122.5 million | $48.5 million | 2025-06 |
| Saint Thomas Regional Hospitals | 501(c)(3) | 1946 | $120.6 million | $79.2 million | 2025-06 | |
| Easter Seals Midwest | 501(c)(3) | 1971 | $119 million | $111.5 million | 2025-06 | |
| St John Broken Arrow Inc | Health care | 501(c)(3) | 1946 | $115.2 million | $147 million | 2025-06 |
| St Marys Medical Group LLC | Health care | 501(c)(3) | 2015 | $112 million | $27.9 million | 2025-06 |
| Saint Thomas Health | Health care | 501(c)(3) | 1988 | $109.7 million | $72.7 million | 2025-06 |
| Ascension Via Christi Hospital Manhattan Inc | Health care | 501(c)(3) | 1997 | $108.1 million | $63.9 million | 2025-06 |
| The Foundation for Barnes-Jewish Hospital | Health care | 501(c)(3) | 1993 | $106.3 million | $927.6 million | 2024-12 |
| St Vincent Fishers Hospital Inc | Health care | 501(c)(3) | 1946 | $101.5 million | $71.7 million | 2025-06 |
| Beacon Medical Group Michigan Inc | Health care | 501(c)(3) | 1996 | $98.4 million | $6.8 million | 2025-06 |
| St Vincents Ambulatory Care Inc | 501(c)(3) | 1946 | $92.9 million | $36.5 million | 2025-06 | |
| Ibew-1 Health & Welfare Fund | 501(c)(9) | 1956 | $85.1 million | $185.7 million | 2024-12 | |
| Gateway Region Young Mens Christian Association | Human services | 501(c)(3) | 1937 | $84 million | $178.1 million | 2025-12 |
| Seton-Ut Austin Dell Medical School University Physicians Group | Health care | 501(c)(3) | 2014 | $82.8 million | $27 million | 2025-06 |
| Alexian Brothers Ambulatory Group | Health care | 501(c)(3) | 2001 | $80 million | $625.9 million | 2025-06 |
| Mary Institute and Saint Louis Country Day School | Education | 501(c)(3) | 1949 | $78.6 million | $299.8 million | 2025-06 |
| St Louis Municipal Finance Corporation | Public and societal benefit | 501(c)(3) | 1993 | $75.9 million | $68.3 million | 2025-06 |
| Alexian Brothers Behavioral Health Hospital | 501(c)(3) | 1946 | $75.1 million | $33.4 million | 2025-06 | |
| Ascension Via Christi Health Inc | Health care | 501(c)(3) | 1946 | $74.6 million | $222.7 million | 2025-06 |
| International Brotherhood of Elec Workers 683 Health & Welfare Fund | 501(c)(9) | 1968 | $74 million | $67.4 million | 2025-05 | |
| Providence Health Alliance Inc | Health care | 501(c)(3) | 1999 | $71.7 million | $19.8 million | 2025-06 |
| Missouri Baptist University | Education | 501(c)(3) | 2003 | $70.7 million | $94.6 million | 2025-06 |
| Greater St Louis Construction Laborers Welfare Fund | 501(c)(9) | 1954 | $68.9 million | $116.7 million | 2025-06 | |
| United Way of Greater St Louis Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1957 | $68.6 million | $122.5 million | 2025-06 |
| Cardinal Glennon Childrens Foundation | 501(c)(3) | 1946 | $66.9 million | $268.7 million | 2024-12 | |
| Ascension Via Christi Hospital St Teresa Inc | Health care | 501(c)(3) | 1946 | $65.6 million | $61.7 million | 2025-06 |
| Donald Danforth Plant Science Center | Science and technology | 501(c)(3) | 1998 | $63.8 million | $625.7 million | 2024-12 |
| Friendship Village of South County | Human services | 501(c)(3) | 1980 | $63.1 million | $282.4 million | 2025-06 |
| Leonard & Beryl Buck Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1980 | $62.8 million | $1.13 billion | 2025-06 |
| Alexian Brothers Specialty Group | Health care | 501(c)(3) | 2012 | $62.1 million | $12.1 million | 2025-06 |
| Presence Healthcare Services | Health care | 501(c)(3) | 1946 | $61.7 million | $60.4 million | 2025-06 |
| Missouri Botanical Garden Board of Trustees | Environment | 501(c)(3) | 1937 | $61 million | $414.1 million | 2025-09 |
| Ameren Health & Welfare Trust | 501(c)(9) | 1997 | $57.7 million | $772.4 million | 2024-12 | |
| Urban League of Metropolitan St Louis | 501(c)(3) | 1975 | $56.4 million | $81.2 million | 2024-12 | |
| Confluence Academy | Education | 501(c)(3) | 2005 | $55.8 million | $65.1 million | 2025-06 |
| Saint Louis Symphony Orchestra | Arts, culture and humanities | 501(c)(3) | 1926 | $54.7 million | $232.2 million | 2025-08 |
| The Saint Louis Zoo Foundation | Animal-related | 501(c)(3) | 1995 | $53.8 million | $334.8 million | 2025-12 |
| Lighthouse for the Blind | 501(c)(3) | 1938 | $53.1 million | $116.3 million | 2024-12 | |
| Affinia Healthcare | 501(c)(3) | 1973 | $52.2 million | $48.1 million | 2024-12 | |
| Kipp St Louis | 501(c)(3) | 2010 | $52 million | $70.9 million | 2025-06 | |
| SSMHCS Liability Trust Mercantile Bank Ttee | Mutual and membership benefit | 501(c)(3) | 1987 | $51.4 million | $205.1 million | 2024-12 |
| John Burroughs School | Education | 501(c)(3) | 1934 | $50.4 million | $237.1 million | 2025-06 |
| Owasso Medical Facility Inc | Health care | 501(c)(3) | 1946 | $49 million | $48.6 million | 2025-06 |
| St Louis Regional Public Media Inc | Arts, culture and humanities | 501(c)(3) | 1955 | $48.1 million | $67.5 million | 2025-06 |
| Ranken Technical College | Education | 501(c)(3) | 1935 | $47.9 million | $155.6 million | 2025-06 |
| St Louis Arc Inc | Human services | 501(c)(3) | 1954 | $46.3 million | $52.4 million | 2025-06 |
| University of Health Sciences and Pharmacy in St Louis | Education | 501(c)(3) | 1938 | $45.3 million | $235.6 million | 2025-06 |
| Operation Food Search Inc | Food, agriculture and nutrition | 501(c)(3) | 1982 | $43.7 million | $37.8 million | 2025-09 |
| Worldwide Inventory Network Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1991 | $43.2 million | $163.1 million | 2024-12 |
| Forest Park Forever Inc | Environment | 501(c)(3) | 1987 | $42.3 million | $246.2 million | 2024-12 |
| International Institute of Metropolitan St Louis | Human services | 501(c)(3) | 1938 | $41.3 million | $11.4 million | 2024-12 |
| American Soybean Association | 501(c)(5) | 1981 | $40.9 million | $20.9 million | 2025-09 | |
| Presence Life Connections | 501(c)(3) | 1946 | $40.1 million | $18.6 million | 2025-06 | |
| Municipal Theatre Association of St Louis | Arts, culture and humanities | 501(c)(3) | 1939 | $39.4 million | $138.9 million | 2025-09 |
| Ascension Living Bethlehem Woods Village | Health care | 501(c)(3) | 1946 | $38.1 million | $18.8 million | 2025-06 |
| Catholic Health Association | Health care | 501(c)(3) | 1946 | $37 million | $76.3 million | 2025-06 |
| Wheaton Franciscan Healthcare - Southeast Wisconsin Inc | Health care | 501(c)(3) | 1946 | $37 million | $90.2 million | 2025-06 |
| St John Sapulpa Inc | Health care | 501(c)(3) | 1959 | $36.9 million | $12.5 million | 2025-06 |
| Alexian Brothers Community Services | 501(c)(3) | 1946 | $36.9 million | $50.1 million | 2025-06 | |
| International Association of Sheet Metal Air Rail and Transportation Worker | 501(c)(9) | 1954 | $36.1 million | $61 million | 2024-12 | |
| Gateway Science Academy of St Louis | Education | 501(c)(3) | 2013 | $35.9 million | $17.9 million | 2025-06 |
| Ameren Management Health Trust | 501(c)(9) | 1997 | $35.5 million | $517.9 million | 2024-12 | |
| Carestl Health | 501(c)(3) | 1971 | $35.5 million | $9.7 million | 2023-12 | |
| Ascension Via Christi Health Partners Inc | Health care | 501(c)(3) | 1946 | $35.3 million | $46.3 million | 2025-06 |
| Opera Theatre of Saint Louis | Arts, culture and humanities | 501(c)(3) | 1966 | $34.9 million | $131.1 million | 2025-09 |
| Betty Jean Kerr Peoples Health Centers Inc | Health care | 501(c)(3) | 1975 | $34 million | $28.3 million | 2025-05 |
| Ascension Living Carroll Manor | 501(c)(3) | 1946 | $33 million | $11.6 million | 2025-06 | |
| Beacon Allegan Inc | Health care | 501(c)(3) | 1944 | $32.9 million | $16.2 million | 2025-06 |
| Ascension Calumet Hospital Inc | 501(c)(3) | 1946 | $32.3 million | $16.4 million | 2025-06 | |
| St Vincent Health Wellness and Preventive Care Institute Inc | Health care | 501(c)(3) | 2015 | $31.8 million | $28.1 million | 2025-06 |
| Humane Society of Missouri | Animal-related | 501(c)(3) | 1941 | $31.6 million | $150.6 million | 2025-10 |
| Chess Club and Scholastic Center of Saint Louis | Recreation and sports | 501(c)(3) | 2008 | $31.2 million | $29 million | 2024-12 |
| Voluntary Interdistrict Choice Corporation | Education | 501(c)(3) | 1999 | $31.1 million | $31.7 million | 2025-06 |
| Concordia Disability and Survivor Plan | 501(c)(9) | 1969 | $30.5 million | $157.9 million | 2024-12 | |
| St Vincent Randolph Hospital Inc | Health care | 501(c)(3) | 2000 | $29.7 million | $14.2 million | 2025-06 |
| International Brotherhood of Electrical Workers Vacation Fund | 501(c)(9) | 1968 | $29.5 million | $30.1 million | 2024-12 | |
| Nazareth Living Center | Health care | 501(c)(3) | 1946 | $29.3 million | $75.3 million | 2025-06 |
| Ascension Living Alexian Village Tennesee | Human services | 501(c)(3) | 1946 | $28.8 million | $66.1 million | 2025-06 |
| Family Care Health Centers | Health care | 501(c)(3) | 1974 | $28.6 million | $31.7 million | 2025-01 |
| Ibew-Neca Holiday Trust Fund Local No 1 | 501(c)(9) | 1970 | $28 million | $32.7 million | 2025-10 | |
| St Vincent Williamsport Hospital Inc | 501(c)(3) | 1946 | $27.9 million | $11.2 million | 2025-06 | |
| Dell Childrens Foundation | 501(c)(3) | 1946 | $27.8 million | $115.9 million | 2025-06 | |
| Seton Medical Group Inc | Health care | 501(c)(3) | 2010 | $27.6 million | $35.2 million | 2025-06 |
| Alexian Health Senior Care | Health care | 501(c)(3) | 1946 | $26.3 million | $61.7 million | 2025-06 |
| Jewish Community Center | Human services | 501(c)(3) | 1953 | $26.1 million | $79.1 million | 2024-12 |
| Ascension Via Christi Rehabilitation Hospital Inc | Health care | 501(c)(3) | $26 million | $18.5 million | 2025-06 | |
| Saint Johns Health System | Health care | 501(c)(3) | 1946 | $25.9 million | $15.9 million | 2025-06 |
| St Vincent Hospital Foundation Inc | Health care | 501(c)(3) | 1968 | $25.4 million | $191.4 million | 2025-06 |
| Society of St Vincent de Paul Archdiocesan Council of St Louis | Human services | 501(c)(3) | 2012 | $25.3 million | $14.6 million | 2025-09 |
| Home Health United Inc | Health care | 501(c)(3) | 1986 | $25.3 million | $5.5 million | 2024-12 |
| St Louis Art Museum Foundation | Arts, culture and humanities | 501(c)(3) | 1985 | $25.1 million | $357.9 million | 2025-12 |
| Ascension Living Providence Village | 501(c)(3) | 1946 | $24 million | $12.1 million | 2025-06 | |
| St Louis Development Coroporation | 501(c)(4) | 1995 | $24 million | $52.6 million | 2025-06 | |
| Carpenters Vacation Trust Fund of St Louis | 501(c)(9) | 1970 | $23.8 million | $29.4 million | 2025-04 | |
| Missouri Historical Society Jefferson Memorial Building | Arts, culture and humanities | 501(c)(3) | 1943 | $23.6 million | $167.8 million | 2025-12 |
| St Vincent Jennings Hospital Inc | Health care | 501(c)(3) | 1946 | $23.4 million | $11.3 million | 2025-06 |
| Urban Strategies Inc | Human services | 501(c)(3) | 1980 | $23.4 million | $9.3 million | 2024-12 |
| St Andrews Resources for Seniors | Human services | 501(c)(3) | 1964 | $23.3 million | $67.3 million | 2025-05 |
| Baptist Health Care Affiliates Inc | Health care | 501(c)(3) | 1983 | $23.2 million | $46 million | 2025-06 |
| Saint Thomas Network | Health care | 501(c)(3) | 1946 | $23.2 million | $56.3 million | 2025-06 |
| Alexian Brothers Hospital Network | Health care | 501(c)(3) | 1946 | $23 million | $74.6 million | 2025-06 |
| St Vincent Seton Specialty Hospital Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 1946 | $21.8 million | $15.6 million | 2025-06 |
| Central Institute for the Deaf | Education | 501(c)(3) | 1934 | $21.7 million | $128.6 million | 2025-08 |
| Wamego Hospital Association | Health care | 501(c)(3) | 2003 | $21.2 million | $27.5 million | 2025-06 |
| The Sarah Community | Human services | 501(c)(3) | 1946 | $21.1 million | $35.2 million | 2024-12 |
| Ascension Living Franciscan Place | Health care | 501(c)(3) | 1946 | $20.9 million | $4.3 million | 2025-06 |
| St Patrick Center | 501(c)(3) | 1946 | $20.8 million | $18.3 million | 2025-06 | |
| Lift for Life Academy Inc | Recreation and sports | 501(c)(3) | 1991 | $20.7 million | $24.7 million | 2025-06 |
| Parents As Teachers National Center Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 1991 | $20.5 million | $33 million | 2025-06 |
| St Vincent Salem Hospital Inc | 501(c)(3) | 1946 | $20.4 million | $7.2 million | 2025-06 | |
| St Vincent Clay Hospital Inc | Health care | 501(c)(3) | 1946 | $20.3 million | $16.6 million | 2025-06 |
| Missouri Athletic Club | 501(c)(7) | 1938 | $20.3 million | $25.8 million | 2025-08 | |
| Jewish Federation of St Louis | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1947 | $20 million | $152.7 million | 2024-12 |
| Premier Charter School | Education | 501(c)(3) | 2000 | $20 million | $22.6 million | 2025-06 |
| United Cerebral Palsy Heartland | Diseases, disorders and medical disciplines | 501(c)(3) | 1969 | $19.8 million | $29.6 million | 2025-06 |
| St Marys Warrick Hospital Inc | Health care | 501(c)(3) | 1973 | $19.8 million | $10.6 million | 2025-06 |
| Home Care United | Health care | 501(c)(3) | 1995 | $19.4 million | $10.9 million | 2024-12 |
| Hope Educational & Research Center | Education | 501(c)(3) | 1973 | $19.1 million | $191.4 million | 2025-06 |
| Whitfield School Inc | 501(c)(3) | 1969 | $18.5 million | $38.1 million | 2025-06 | |
| St Louis Country Club | 501(c)(7) | 1942 | $18.4 million | $28.5 million | 2025-01 | |
| Interfaith Residence | Diseases, disorders and medical disciplines | 501(c)(3) | 1988 | $18.4 million | $25.7 million | 2025-06 |
| Lutheran Family and Childrens Services of Missouri | 501(c)(3) | 1957 | $17.9 million | $13.3 million | 2024-12 | |
| Bellerive Country Club | 501(c)(7) | 1942 | $17.6 million | $30.8 million | 2025-09 | |
| Greater St Louis Inc | Community improvement and capacity building | 501(c)(6) | 2021 | $17.5 million | $8.6 million | 2024-12 |
| Ascension Living Via Christi Village Hays | 501(c)(3) | 1946 | $17.3 million | $8.4 million | 2025-06 | |
| Ascension Seton Foundation | 501(c)(3) | 1946 | $17.2 million | $142.4 million | 2025-06 | |
| Saint Thomas Hickman Hospital | Health care | 501(c)(3) | 1946 | $17.2 million | $26.2 million | 2025-06 |
| Services By Design Inc | Human services | 501(c)(3) | 2002 | $16.9 million | $10.3 million | 2025-12 |
| Concordance Academy of Leadership | Crime and legal-related | 501(c)(3) | 1986 | $16.9 million | $34.5 million | 2024-12 |
| Ascension Living Via Christi Village Ridge | Human services | 501(c)(3) | 1946 | $16.7 million | $15.8 million | 2025-06 |
| Kidsmart | Education | 501(c)(3) | 2001 | $16.6 million | $19.4 million | 2025-06 |
| Seton Family of Pediatric Surgeons | Health care | 501(c)(3) | 2014 | $16.6 million | $2.1 million | 2025-06 |
| Beacon Dowagiac Inc | Health care | 501(c)(3) | 1954 | $16.5 million | $6.2 million | 2025-06 |
| Girl Scouts of Eastern Missouri Inc | 501(c)(3) | 1953 | $16.5 million | $46.6 million | 2025-09 | |
| Westwood Country Club | 501(c)(7) | 1941 | $16.5 million | $21.2 million | 2025-09 | |
| Judevine Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 2009 | $16.3 million | $12.5 million | 2025-06 |
| Ascension Living Alexian Village Milwaukee | Human services | 501(c)(3) | 1946 | $16.3 million | $20 million | 2025-06 |
| Ascension Living St Francis Place | 501(c)(3) | 1946 | $16.2 million | $9 million | 2025-06 | |
| St John Health System Foundation Inc | Health care | 501(c)(3) | 1946 | $16.1 million | $89.1 million | 2025-06 |
| Bellefontaine Cemetery Association | 501(c)(13) | 1936 | $16 million | $170.1 million | 2024-12 | |
| Old Warson Country Club | 501(c)(7) | 1956 | $15.9 million | $35.4 million | 2025-10 | |
| Behavioral Health Response Inc | Mental health and crisis intervention | 501(c)(3) | 1996 | $15.7 million | $8.1 million | 2025-06 |
| St Louis Community Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1950 | $15.4 million | $104 million | 2024-12 |
| Hope Montessori Academy | Education | 501(c)(3) | 2003 | $15.4 million | $2.3 million | 2025-06 |
| Momentum Academy | Education | 501(c)(3) | 2013 | $14.9 million | $4.4 million | 2025-06 |
| Animal Protective Association of Missouri | Animal-related | 501(c)(3) | 1945 | $14.8 million | $34.1 million | 2025-05 |
| Beyond Housing Inc | Housing and shelter | 501(c)(3) | 1976 | $14.8 million | $35.9 million | 2024-12 |
| Evangelical Childrens Home | Human services | 501(c)(3) | 1958 | $14.7 million | $42.4 million | 2025-09 |
| International Brotherhood of Electrical Workers | 501(c)(5) | 1940 | $14.6 million | $27.5 million | 2025-06 | |
| Presence Behavioral Health | Mental health and crisis intervention | 501(c)(3) | 1972 | $14.6 million | $2.9 million | 2025-06 |
| St John Building Corporation | Community improvement and capacity building | 501(c)(2) | 2012 | $14.5 million | $173.8 million | 2025-06 |
| Independence Center | 501(c)(3) | 1980 | $14.4 million | $20.9 million | 2025-06 | |
| St Vincents Foundation Inc | 501(c)(3) | 1946 | $14.3 million | $84.2 million | 2025-06 | |
| Ascension Living Our Lady of Peace | 501(c)(3) | 1946 | $14.2 million | $17.5 million | 2024-12 | |
| St Louis Labor Healthcare Network | Mutual and membership benefit | 501(c)(9) | 2011 | $14.1 million | $56 million | 2025-06 |
| Legal Services of Eastern Mo Inc | Crime and legal-related | 501(c)(3) | 1970 | $14 million | $54.9 million | 2024-12 |
| Scholarship Foundation of St Louis | 501(c)(3) | 1983 | $13.8 million | $51.4 million | 2025-12 | |
| Mary Queen and Mother Association | Human services | 501(c)(3) | 1981 | $13.7 million | $4.3 million | 2025-06 |
| City Academy Inc | Education | 501(c)(3) | 1998 | $13.5 million | $79.6 million | 2025-06 |
| Southampton Community Healthcare Inc | Health care | 501(c)(3) | 2022 | $13.3 million | $2 million | 2024-12 |
| Forsyth School Inc | Education | 501(c)(3) | 1968 | $13.3 million | $30.6 million | 2025-06 |
| Telecommunication Facilities Corporation | 501(c)(12) | 1984 | $13.3 million | $30.8 million | 2024-12 | |
| Foster Care Coalition of Greater St Louis Inc | 501(c)(3) | 1991 | $13.2 million | $17.5 million | 2025-12 | |
| National Association of Electrical Distributors | 501(c)(6) | 1952 | $13.2 million | $16.5 million | 2025-06 | |
| Ascension Living Via Christi Village Manhattan | 501(c)(3) | $13.2 million | $10.6 million | 2025-06 | ||
| Novus Health Inc | Medical research | 501(c)(3) | 2004 | $13 million | $14.6 million | 2025-12 |
| The Launchcode Foundation | Education | 501(c)(3) | 2014 | $13 million | $17 million | 2024-12 |
| Good Samaritan Independent Living Inc | Human services | 501(c)(3) | 1999 | $12.9 million | $50.2 million | 2025-05 |
| Sunset Country Club | 501(c)(7) | 1947 | $12.9 million | $15.4 million | 2025-09 | |
| Local Union 682 Health & Welfare Trust Fund | 501(c)(9) | 1964 | $12.8 million | $13.6 million | 2024-12 | |
| Carpenters Joint Training Fund of St Louis | Education | 501(c)(3) | 2003 | $12.8 million | $22.9 million | 2023-04 |
| Paraquad Inc | 501(c)(3) | 1977 | $12.7 million | $16.2 million | 2025-09 | |
| Ascension Via Christi Hospital Pittsburg Inc | Health care | 501(c)(3) | 1946 | $12.6 million | $278,730 | 2025-06 |
| Ascension Wisconsin Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1984 | $12.6 million | $99 million | 2025-06 |
| Ascension Living Via Christi Village Pittsburg | 501(c)(3) | 1946 | $12.4 million | $8.5 million | 2025-06 | |
| Tri-County Clinical | Health care | 501(c)(3) | 2014 | $12.4 million | $2.8 million | 2025-06 |
| Village North Inc | Human services | 501(c)(3) | 2016 | $12.3 million | $7.2 million | 2024-12 |
| Cortex | Community improvement and capacity building | 501(c)(3) | 2002 | $12.3 million | $81.8 million | 2024-12 |
| Queen of Peace Center | Mental health and crisis intervention | 501(c)(3) | 1946 | $12.1 million | $5.8 million | 2025-06 |
| Saint Louis Symphony Endowment Trust | Arts, culture and humanities | 501(c)(3) | 2001 | $12 million | $278.7 million | 2025-08 |
| Missouri Valley Conference Inc | Recreation and sports | 501(c)(3) | 2000 | $12 million | $10.1 million | 2025-06 |
| Roman Catholic Foundation of Eastern Missouri | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2014 | $11.8 million | $89.7 million | 2025-12 |
| St Louis Office for MR DD Resources | 501(c)(3) | 1982 | $11.8 million | $20.6 million | 2025-06 | |
| Miriam Foundation | Education | 501(c)(3) | 1957 | $11.7 million | $33.3 million | 2025-06 |
| City Garden Montessori School | Education | 501(c)(3) | 1995 | $11.6 million | $15.4 million | 2025-06 |
| The Childrens Home Society of Missouri | Human services | 501(c)(3) | 1941 | $11.6 million | $40 million | 2024-12 |
| New City School Inc | 501(c)(3) | 1968 | $11.6 million | $33.6 million | 2025-06 | |
| Humphreys County Community Health Services Inc | Health care | 501(c)(3) | 2010 | $11.5 million | $7.9 million | 2025-06 |
| Epworth Children & Family Services Inc | 501(c)(3) | 2009 | $11.5 million | $21.4 million | 2024-12 | |
| Community School Association | 501(c)(3) | 1937 | $11.5 million | $46 million | 2025-06 | |
| Planned Parenthood Great Rivers-Missouri | Health care | 501(c)(3) | 1952 | $11.5 million | $13.5 million | 2025-06 |
| Missouri Baptist Healthcare Foun Att Janice Burnett | Health care | 501(c)(3) | 1996 | $11.3 million | $74.5 million | 2024-12 |
| The St Anthony Hospital Foundation Inc Oklahoma City Oklahoma | Health care | 501(c)(3) | 1964 | $11.3 million | $49.8 million | 2024-12 |
| Youthbridge Community Foundation | Human services | 501(c)(3) | 1944 | $11.2 million | $105.2 million | 2024-12 |
| Mercy Health Foundation St Louis | Health care | 501(c)(3) | 2004 | $11.2 million | $47.4 million | 2025-06 |
| Missouri Corporation for Science and Technology | 501(c)(3) | 1986 | $11.2 million | $105.2 million | 2025-06 | |
| Magdala Foundation Magdala House | Mental health and crisis intervention | 501(c)(3) | 1967 | $11.1 million | $5.9 million | 2025-06 |
| Kairos Academies | Education | 501(c)(3) | 2017 | $11.1 million | $2.9 million | 2025-06 |
| St Louis Science Center Foundation | Science and technology | 501(c)(3) | 1989 | $10.8 million | $55.2 million | 2025-12 |
| Catholic Charities of St Louis | Human services | 501(c)(3) | 1946 | $10.7 million | $6.7 million | 2025-06 |
| Ascension Living-Lakeshore at Siena Inc | 501(c)(3) | 1946 | $10.6 million | $4.6 million | 2025-06 | |
| Parsons Blewett Memorial Fund | Education | 501(c)(3) | 1961 | $10.6 million | $86.9 million | 2025-12 |
| Alexian Brothers Medical Group Specialty Care | Health care | 501(c)(3) | 2018 | $10.4 million | $1.2 million | 2025-06 |
| Progress in Education Inc | Education | 501(c)(3) | 2008 | $10.4 million | $4 million | 2025-06 |
| Api Innovation Center | Human services | 501(c)(3) | 2022 | $10.3 million | $5.1 million | 2024-12 |
| Sacred Heart Rehabilitation Institute Inc | Health care | 501(c)(3) | 1946 | $10.3 million | $7.6 million | 2025-06 |
| Peter and Paul Community Services Inc | Housing and shelter | 501(c)(3) | 1985 | $10.3 million | $12.1 million | 2025-06 |
| Mid-America Carpenters Regional Benefit Services Inc | Employment | 501(c)(5) | 2022 | $10.1 million | $1.4 million | 2025-12 |
| Mother of Perpetual Help Residence Inc | 501(c)(3) | 1946 | $10.1 million | $11.9 million | 2025-06 | |
| Fox Performing Arts Charitable Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2002 | $9.9 million | $5.3 million | 2025-06 |
| Ronald McDonald House Charities of St Louis | 501(c)(3) | 1979 | $9.9 million | $30.9 million | 2025-12 | |
| International Union of Painters and Allied Trades | 501(c)(5) | 1941 | $9.9 million | $13.9 million | 2025-06 | |
| Mission St Louis | Community improvement and capacity building | 501(c)(3) | 2008 | $9.9 million | $4.5 million | 2024-12 |
| Saint Thomas Health Foundations | 501(c)(3) | 1946 | $9.8 million | $91.6 million | 2025-06 | |
| SSM Health Foundation St Louis | 501(c)(3) | 1946 | $9.8 million | $37.1 million | 2024-12 | |
| St Louis Language Immersion Schools Inc | Education | 501(c)(3) | 2010 | $9.8 million | $7.3 million | 2025-06 |
| Employers & Laborers Locals 100 & 397 Health & Welfare Fund | 501(c)(9) | 1967 | $9.7 million | $14.9 million | 2025-07 | |
| Atlas Public Schools | Education | 501(c)(3) | 2019 | $9.6 million | $26.7 million | 2025-06 |
| Magic House | Arts, culture and humanities | 501(c)(3) | 1977 | $9.6 million | $37.2 million | 2025-12 |
| International Association of Sheet Metal Air Rail & Transportation | Employment | 501(c)(5) | 2015 | $9.6 million | $17.5 million | 2025-12 |
| Good Shepherd Children and Family Services | 501(c)(3) | 1946 | $9.5 million | $17.1 million | 2025-06 | |
| Ascension Living Via Christi Village Ponca City | Human services | 501(c)(3) | 1946 | $9.5 million | $3.3 million | 2025-06 |
| Providence Hospital | Health care | 501(c)(3) | 1946 | $9.4 million | $5.1 million | 2025-06 |
| Boys & Girls Clubs of Greater St Louis Inc | Youth development | 501(c)(3) | 1966 | $9.3 million | $31.5 million | 2024-12 |
| Mother of Good Counsel Home | Health care | 501(c)(3) | 1946 | $9.3 million | $5.7 million | 2024-12 |
| Greater St Louis Inc Foundation | Community improvement and capacity building | 501(c)(3) | 1994 | $9.2 million | $16.1 million | 2024-12 |
| Better Family Life Inc | Community improvement and capacity building | 501(c)(3) | 1985 | $9.2 million | $12.1 million | 2024-12 |
| FV Services Inc | Housing and shelter | 501(c)(3) | 2017 | $9.1 million | $5.5 million | 2025-06 |
| St Louis Economic Development Partnership | 501(c)(4) | 1985 | $9.1 million | $39.6 million | 2025-09 | |
| Ascension Foundation | 501(c)(3) | 1946 | $9 million | $97.1 million | 2025-06 | |
| St Agnes Hospital Foundation Inc | Health care | 501(c)(3) | 1946 | $9 million | $30.6 million | 2025-06 |
| Gateway Creative Broadcasting Inc | Arts, culture and humanities | 501(c)(3) | 1998 | $8.7 million | $20.4 million | 2025-05 |
| Catholic Charities Foundation | 501(c)(3) | 1946 | $8.7 million | $20.5 million | 2025-06 | |
| Rossman School | 501(c)(3) | 1961 | $8.6 million | $42.7 million | 2025-06 | |
| Churchill Center and School for Learning Disabilities | 501(c)(3) | 1978 | $8.6 million | $31.2 million | 2025-05 | |
| The Backstoppers Inc | 501(c)(3) | 1961 | $8.6 million | $74 million | 2024-12 | |
| Algonquin Golf Club | 501(c)(7) | 1936 | $8.6 million | $18.2 million | 2025-10 | |
| St Louis Integrated Health Network | Medical research | 501(c)(3) | 2006 | $8.5 million | $6.5 million | 2025-08 |
| Ascension Living Via Christi Village McLean | 501(c)(3) | 1946 | $8.3 million | $7.9 million | 2025-06 | |
| Jewish Family Services of St Louis | Human services | 501(c)(3) | 1964 | $8.3 million | $22.1 million | 2025-12 |
| Saint Thomas Rutherford Foundation | 501(c)(3) | 1984 | $8.2 million | $15.2 million | 2025-06 | |
| Westborough Country Club | 501(c)(7) | 1950 | $8.1 million | $18.9 million | 2025-09 | |
| Provident Inc | Mental health and crisis intervention | 501(c)(3) | 1957 | $7.9 million | $9.4 million | 2025-12 |
| The Oasis Institute | Human services | 501(c)(3) | 2001 | $7.7 million | $2.9 million | 2024-12 |
| United States of America Chess Federation | Human services | 501(c)(3) | 2014 | $7.7 million | $6.9 million | 2025-06 |
| Child Center Marygrove | Mental health and crisis intervention | 501(c)(3) | 1946 | $7.6 million | $7.2 million | 2025-06 |
| Ascension Living St Vincent Pace Inc | 501(c)(3) | 1946 | $7.6 million | $12.7 million | 2025-06 | |
| Lafayette Preparatory Academy Inc | Education | 501(c)(3) | 2012 | $7.5 million | $7.5 million | 2025-06 |
| Teamsters Medicare Trust for Retired Employees | 501(c)(9) | 1967 | $7.4 million | $40.2 million | 2024-12 | |
| Big Brothers Big Sisters of Eastern Missouri | 501(c)(3) | 1942 | $7.4 million | $23.7 million | 2025-12 | |
| Arch City Defenders Inc | Crime and legal-related | 501(c)(3) | 2010 | $7.3 million | $6.3 million | 2025-06 |
| Pedal the Cause | Human services | 501(c)(3) | 2010 | $7.3 million | $2.8 million | 2025-12 |
| St Louis Crisis Nursery | 501(c)(3) | 1986 | $7.3 million | $9 million | 2025-06 | |
| Greenbriar Hills Country Club | 501(c)(7) | 1952 | $7.3 million | $11.8 million | 2025-12 | |
| St Louis Sheet Metal Joint Apprenticeship Fund | 501(c)(5) | 1977 | $7.2 million | $5.8 million | 2024-12 | |
| Stray Rescue of St Louis | Animal-related | 501(c)(3) | 1998 | $7.2 million | $8.9 million | 2024-12 |
| Ascension Via Christi Property Services Inc | 501(c)(4) | 2009 | $7.1 million | $36.7 million | 2025-06 | |
| Habitat for Humanity International Inc | Housing and shelter | 501(c)(3) | 1987 | $7.1 million | $15.4 million | 2024-12 |
| College School Association | 501(c)(3) | 1979 | $6.9 million | $8.1 million | 2025-05 | |
| Providence Health Services Inc | Health care | 501(c)(3) | 1946 | $6.7 million | $1.5 million | 2025-06 |
| International Crisis Aid Inc | Human services | 501(c)(3) | 2002 | $6.6 million | $5.9 million | 2025-12 |
| Laborers International Union of North America | 501(c)(5) | 1964 | $6.5 million | $38.4 million | 2025-06 | |
| American Association of Bioanalysts | 501(c)(6) | 1959 | $6.5 million | $8.2 million | 2024-12 | |
| Feed My People | Human services | 501(c)(3) | 1982 | $6.4 million | $5.4 million | 2024-12 |
| Moneta Group Employee Benefit Plan Trust | Mutual and membership benefit | 501(c)(9) | 2016 | $6.3 million | $4 million | 2024-12 |
| International Brotherhood of Teamsters | 501(c)(5) | 1941 | $6.3 million | $4.1 million | 2025-12 | |
| Center of Creative Arts | Arts, culture and humanities | 501(c)(3) | 1986 | $6.3 million | $16.1 million | 2025-08 |
| Prevented | Mental health and crisis intervention | 501(c)(3) | 1965 | $6.2 million | $5.7 million | 2024-12 |
| St Louis Laborers Vacation Fund | 501(c)(9) | 1970 | $6.2 million | $2.9 million | 2024-12 | |
| Sacred Heart Foundation | Health care | 501(c)(3) | 1946 | $6.2 million | $26.8 million | 2025-06 |
| Ibew-Neca Service Center | 501(c)(5) | 1979 | $6.1 million | $1.7 million | 2024-12 | |
| Employment Connection | 501(c)(3) | 1977 | $6.1 million | $7 million | 2024-12 | |
| St Louis Life Sciences Project | Medical research | 501(c)(3) | 2004 | $6.1 million | $5.8 million | 2024-12 |
| Alexian Brothers Center for Mental Health | Mental health and crisis intervention | 501(c)(3) | 1980 | $6 million | $7.4 million | 2025-06 |
| Criminal Justice Ministry | Crime and legal-related | 501(c)(3) | 2014 | $6 million | $5.9 million | 2025-06 |
| Hhu Xtra Care Inc | Human services | 501(c)(3) | 1996 | $6 million | $2 million | 2024-12 |
| St Louis Counseling Inc | 501(c)(3) | 1946 | $5.9 million | $2.7 million | 2025-06 | |
| Incarnate Word Academy | Education | 501(c)(3) | 1995 | $5.9 million | $12.7 million | 2025-06 |
| Stephen Ministries | Religion-related | 501(c)(3) | 1976 | $5.9 million | $31.5 million | 2025-08 |
| Better Business Bureau of Greater St Louis Inc | 501(c)(6) | 1927 | $5.9 million | $4.2 million | 2024-12 | |
| Rainbow Hospice and Palliative Care | 501(c)(3) | 1984 | $5.9 million | $2.9 million | 2025-06 | |
| Electrical Apparatus Service Association Inc | 501(c)(6) | 1949 | $5.8 million | $11.7 million | 2025-08 | |
| Our Lady of Life Apartments Inc | Human services | 501(c)(3) | 1946 | $5.8 million | $12.5 million | 2025-06 |
| Jefferson National Parks Association Inc | Arts, culture and humanities | 501(c)(3) | 1966 | $5.7 million | $16.5 million | 2025-09 |
| Jane Phillips Nowata Hospital Inc | Health care | 501(c)(3) | 2001 | $5.7 million | $1.5 million | 2025-06 |
| Meds & Food for Kids | International, foreign affairs and national security | 501(c)(3) | 2004 | $5.6 million | $7.1 million | 2025-09 |
| Midwest Stone Institute | 501(c)(3) | 1986 | $5.6 million | $38.1 million | 2025-09 | |
| Alton Ibew-Neca Health & Welfare PL | Mutual and membership benefit | 501(c)(9) | 2006 | $5.6 million | $9 million | 2025-10 |
| Missouri Jobs With Justice | Employment | 501(c)(3) | 2003 | $5.6 million | $4.2 million | 2024-12 |
| Loyola Academy of St Louis | Education | 501(c)(3) | 2015 | $5.6 million | $19.2 million | 2025-06 |
| Lutheran Development Group Inc | Housing and shelter | 501(c)(3) | 2016 | $5.6 million | $8.1 million | 2024-12 |
| Nurses for Newborns | Human services | 501(c)(3) | 1992 | $5.5 million | $7.2 million | 2025-06 |
| Seton Oral & Maxillofacial Surgery | Health care | 501(c)(3) | 2014 | $5.5 million | $2.5 million | 2025-06 |
| Heat Up St Louis Inc | Human services | 501(c)(3) | 2000 | $5.4 million | $4.6 million | 2025-12 |
| Medica Central Health Plan | Health care | 501(c)(4) | 2019 | $5.3 million | $13.4 million | 2024-12 |
| International Association Bridge & Structural Iron Workers 0396 | 501(c)(5) | 1949 | $5.3 million | $14.2 million | 2025-06 | |
| Neighborhood Solidarity Fund | Community improvement and capacity building | 501(c)(3) | 2023 | $5.3 million | $6.8 million | 2025-06 |
| Variety the Childrens Charity of St Louis | 501(c)(3) | 1968 | $5.2 million | $10.6 million | 2025-09 | |
| Torah Center-Midwest Inc | 501(c)(3) | 1970 | $5.2 million | $9.4 million | 2025-07 | |
| Aaim Management Services | Community improvement and capacity building | 501(c)(6) | 1949 | $5.1 million | $9.1 million | 2024-12 |
| Fathers Support Center St Louis | Human services | 501(c)(3) | 1998 | $5.1 million | $6.7 million | 2025-12 |
| The Sheldon Arts Foundation | Arts, culture and humanities | 501(c)(3) | 1994 | $5.1 million | $21.5 million | 2025-06 |
| Sinquefield Center for Research Inc | Education | 501(c)(3) | 2018 | $5 million | $1.2 million | 2025-12 |
| Ibew Apprenticeship and Training Fund-1 | 501(c)(5) | 1956 | $5 million | $7.3 million | 2024-12 | |
| Presence Home Care | 501(c)(3) | 1946 | $4.9 million | $288,770 | 2025-06 | |
| Ministry Health Care Inc | 501(c)(3) | 1946 | $4.9 million | $17.3 million | 2025-06 | |
| Refuge and Restoration | Human services | 501(c)(3) | 2016 | $4.9 million | $25.9 million | 2024-12 |
| St Vincent Dunn Hospital Inc | Health care | 501(c)(3) | 1946 | $4.9 million | $5.3 million | 2025-06 |
| Kingdom House | Youth development | 501(c)(3) | 2011 | $4.8 million | $2.8 million | 2024-12 |
| Circle of Light Associates | Community improvement and capacity building | 501(c)(3) | 1993 | $4.8 million | $2.4 million | 2024-12 |
| Gateway Arch Park Foundation | Recreation and sports | 501(c)(3) | 2010 | $4.8 million | $116.2 million | 2024-12 |
| Leadership School | Education | 501(c)(3) | 2022 | $4.7 million | $648,551 | 2025-06 |
| E T Garsed Trust Ud Fbo | 501(c)(91) | $4.6 million | $4.3 million | 2025-12 | ||
| Peace Haven | Religion-related | 501(c)(3) | 1997 | $4.6 million | $18.8 million | 2025-08 |
| Great Rivers Greenway Foundation | Community improvement and capacity building | 501(c)(3) | 2015 | $4.6 million | $33.1 million | 2024-12 |
| Annie Malone Children and Family Service Center | Human services | 501(c)(3) | 1942 | $4.6 million | $3.8 million | 2025-06 |
| Sacred Heart Health Ventures Inc | 501(c)(3) | 1946 | $4.6 million | $3.8 million | 2025-06 | |
| Eden Theological Seminary | Education | 501(c)(3) | 1969 | $4.6 million | $30.5 million | 2025-06 |
| Southern Illinois Electrical Retiree Welfare Plan | 501(c)(9) | 1996 | $4.5 million | $42.5 million | 2025-08 | |
| Family and Workforce Centers of America | Human services | 501(c)(3) | 2012 | $4.5 million | $1.3 million | 2024-12 |
| Affton Athletic Association Inc | 501(c)(3) | 1973 | $4.5 million | $8.1 million | 2025-06 | |
| Havenhouse St Louis | Health care | 501(c)(3) | 2005 | $4.5 million | $3.7 million | 2025-06 |
| Southside Early Childhood Center | Human services | 501(c)(3) | 1935 | $4.5 million | $5.9 million | 2025-12 |
| St Marys South Side Catholic High School | Education | 501(c)(3) | 2023 | $4.5 million | $3.5 million | 2025-06 |
| St Elizabeth Adult Day Care Center | Human services | 501(c)(3) | 1946 | $4.5 million | $7.7 million | 2025-06 |
| St Louis Regional Crime Commission | Crime and legal-related | 501(c)(3) | 2005 | $4.4 million | $59,839 | 2025-12 |
| Missouri Partnership | Community improvement and capacity building | 501(c)(6) | 2008 | $4.4 million | $3.9 million | 2025-06 |
| Living With Purpose Incorporated | Housing and shelter | 501(c)(3) | 2020 | $4.4 million | $3.2 million | 2024-12 |
| Via Christi Foundation Inc | 501(c)(3) | 1946 | $4.4 million | $28.3 million | 2025-06 | |
| St Andrews Resources for Seniorssystem | Human services | 501(c)(3) | 2008 | $4.4 million | $4.1 million | 2024-05 |
| Lift for Life Foundation Inc | Education | 501(c)(3) | 2018 | $4.4 million | $4.8 million | 2025-06 |
| Believe Schools | Education | 501(c)(3) | 2023 | $4.4 million | $4 million | 2025-06 |
| St Francis Community Services | 501(c)(3) | 1946 | $4.4 million | $3.4 million | 2025-06 | |
| Beacon Health Alliance Inc | Health care | 501(c)(3) | 2026 | $4.3 million | $56.2 million | 2025-06 |
| Laborers International Union of North America | Employment | 501(c)(5) | 1940 | $4.3 million | $8 million | 2025-12 |
| Our Ladys Inn | Human services | 501(c)(3) | 1981 | $4.3 million | $8.4 million | 2025-12 |
| Hope Ignites | Human services | 501(c)(3) | 1976 | $4.3 million | $15.5 million | 2025-06 |
| Missouri Child Care Resource and Referral Network | Human services | 501(c)(3) | 1999 | $4.2 million | $11.8 million | 2025-09 |
| Unleashing Potential | Human services | 501(c)(3) | 1941 | $4.2 million | $1.8 million | 2024-12 |
| Home Sweet Home | Human services | 501(c)(3) | 2016 | $4.2 million | $1.5 million | 2025-12 |
| St Louis Glass & Allied Industries Health & Welfare Insurance Fund | 501(c)(9) | 1980 | $4.2 million | $9.2 million | 2025-10 | |
| The Biome | Education | 501(c)(3) | 2014 | $4.1 million | $1.3 million | 2025-06 |
| Thomas Jefferson School | 501(c)(3) | 1947 | $4.1 million | $7 million | 2025-06 | |
| Donate Life Foundation | Health care | 501(c)(3) | 2014 | $4.1 million | $90.7 million | 2024-12 |
| Covenant House Missouri | Human services | 501(c)(3) | 1998 | $4.1 million | $4.8 million | 2025-06 |
| St Louis Association of Realtors | 501(c)(6) | 1959 | $4 million | $8.1 million | 2024-12 | |
| German St Vincent Orphan Association | 501(c)(3) | 1946 | $4 million | $5.1 million | 2025-12 | |
| National Association of Electrical Distributors Education Foundation | Community improvement and capacity building | 501(c)(3) | 1969 | $4 million | $32.6 million | 2025-06 |
| Ascension Health Global Mission | 501(c)(3) | 1946 | $4 million | $8.4 million | 2024-12 | |
| Bogey Inc | 501(c)(7) | 1945 | $3.9 million | $4.6 million | 2025-12 | |
| Guardian Angel Settlement Association | Human services | 501(c)(3) | 1946 | $3.9 million | $11.5 million | 2024-12 |
| St Louis Police Foundation | Public safety, disaster preparedness and relief | 501(c)(3) | 2007 | $3.9 million | $3.6 million | 2024-12 |
| The Moog Center for Deaf Education | Education | 501(c)(3) | 1997 | $3.9 million | $40.4 million | 2025-06 |
| Optimist International | 501(c)(4) | 1958 | $3.9 million | $6.2 million | 2025-09 | |
| Center for Civic Research and Innovation | Public and societal benefit | 501(c)(3) | 2025 | $3.9 million | $2.5 million | 2025-06 |
| Crossroads School | 501(c)(3) | 1973 | $3.8 million | $7.7 million | 2025-06 | |
| Behavioral Health Network of Greater St Louis | Health care | 501(c)(3) | 2012 | $3.8 million | $5.9 million | 2025-06 |
| Power 4 STL Inc | 501(c)(3) | 2020 | $3.8 million | $1.8 million | 2024-12 | |
| Ascension Living Sherbrooke Village | Human services | 501(c)(3) | 1946 | $3.7 million | $42,649 | 2025-06 |
| Saint Louis Club | 501(c)(7) | 1974 | $3.7 million | $29.1 million | 2025-04 | |
| Industrial Aid Inc | Employment | 501(c)(3) | 1970 | $3.7 million | $6.8 million | 2025-06 |
| Food Outreach Inc | Food, agriculture and nutrition | 501(c)(3) | 1989 | $3.7 million | $6.8 million | 2025-12 |
| Service Employees International Union Local 2000 Health Welfare | 501(c)(5) | 1995 | $3.7 million | $14.3 million | 2024-12 | |
| Racquet Club Ladue | 501(c)(7) | 1984 | $3.7 million | $4.3 million | 2025-08 | |
| American Board of Orthodontics | 501(c)(6) | 1940 | $3.7 million | $15.7 million | 2025-12 | |
| Alexian Brothers Bonaventure House | 501(c)(3) | 1946 | $3.6 million | $6.8 million | 2025-06 | |
| Cornerstone Center for Early Learning Inc | 501(c)(3) | 1970 | $3.6 million | $5.6 million | 2024-12 | |
| Contemporary Art Museum St Louis | Arts, culture and humanities | 501(c)(3) | 1980 | $3.6 million | $30.7 million | 2025-06 |
| Cardinal Carberry Senior Living Center | 501(c)(3) | 1946 | $3.6 million | $2.7 million | 2025-06 | |
| Counterpublic | Arts, culture and humanities | 501(c)(3) | 2022 | $3.6 million | $17.2 million | 2025-12 |
| Racquet Club | 501(c)(7) | 1938 | $3.6 million | $4.4 million | 2025-08 | |
| Electricians Income Security Fund | 501(c)(9) | 1987 | $3.5 million | $40.3 million | 2024-12 | |
| The Tower Grove Park Foundation | 501(c)(3) | 1986 | $3.5 million | $18.2 million | 2025-06 | |
| World Chess Museum Inc | Arts, culture and humanities | 501(c)(3) | 2007 | $3.5 million | $5.3 million | 2024-12 |
| Abortion Action Missouri Foundation | Human services | 501(c)(3) | 1997 | $3.5 million | $2.5 million | 2024-12 |
| Rohan Woods School | Education | 501(c)(3) | 1984 | $3.4 million | $6.9 million | 2025-06 |
| Jazz St Louis | Arts, culture and humanities | 501(c)(3) | 1998 | $3.4 million | $5.8 million | 2025-05 |
| Entrepreneur Startup Business Development Corporation | Community improvement and capacity building | 501(c)(3) | 2011 | $3.4 million | $25.9 million | 2024-12 |
| Action St Louis | Crime and legal-related | 501(c)(3) | 2021 | $3.4 million | $2.2 million | 2025-06 |
| Regional Business Council | Community improvement and capacity building | 501(c)(3) | 2001 | $3.4 million | $4.2 million | 2025-12 |
| Ibew Neca Vacation Fund Local 257 | 501(c)(9) | 1979 | $3.3 million | $2.6 million | 2024-12 | |
| Webster Child Care Center at Laclede Groves | Human services | 501(c)(3) | 1976 | $3.3 million | $5.9 million | 2025-12 |
| Wepower | Community improvement and capacity building | 501(c)(3) | 2018 | $3.3 million | $1.2 million | 2024-12 |
| Flance Management Inc | Human services | 501(c)(3) | 2014 | $3.3 million | $1.6 million | 2025-06 |
| American Civil Liberties Union of Missouri Foundation | 501(c)(3) | 1972 | $3.3 million | $8.5 million | 2025-03 | |
| Monarch Immigrant Services | Human services | 501(c)(3) | 2003 | $3.2 million | $1.5 million | 2025-06 |
| Small Business Empowerment Center | Community improvement and capacity building | 501(c)(3) | 2010 | $3.2 million | $1.6 million | 2025-12 |
| Marian Middle School | Education | 501(c)(3) | 2000 | $3.2 million | $11 million | 2025-06 |
| Planet Indonesia | Environment | 501(c)(3) | 2014 | $3.2 million | $1.2 million | 2025-12 |
| Unite Here Local 74 Welfare and Dental Trust | Mutual and membership benefit | 501(c)(9) | 1953 | $3.2 million | $1.1 million | 2024-12 |
| Painters District Council No 2 Vacation Trust and Plan Agreement | 501(c)(9) | $3.2 million | $2.2 million | 2025-06 | ||
| Missouri Organizing and Voter Engagement Collaborative | Civil rights, social action and advocacy | 501(c)(3) | 1993 | $3.2 million | $2.2 million | 2024-12 |
| Womens Safe House | Human services | 501(c)(3) | 1977 | $3.1 million | $1.9 million | 2024-12 |
| Friends of Kids With Cancer Inc | Human services | 501(c)(3) | 1993 | $3.1 million | $8.7 million | 2024-12 |
| Crown Center | Housing and shelter | 501(c)(3) | 1995 | $3.1 million | $15.7 million | 2025-12 |
| Starkloff Disability Institute | Medical research | 501(c)(3) | 2003 | $3.1 million | $6.1 million | 2024-12 |
| Our Little Haven | 501(c)(3) | 1991 | $3.1 million | $19.3 million | 2025-06 | |
| Rosati-Kain Academy | Education | 501(c)(3) | 2023 | $3.1 million | $1.5 million | 2025-06 |
| Crossroads Christian Counseling | Human services | 501(c)(3) | 1991 | $3 million | $1.2 million | 2025-12 |
| Heartland Industries Incorporated | Employment | 501(c)(3) | 1973 | $3 million | $5.9 million | 2025-06 |
| A Million Stars Inc | Youth development | 501(c)(3) | 2006 | $3 million | $6.4 million | 2025-12 |
| West End Clinic Inc | Mental health and crisis intervention | 501(c)(3) | 2005 | $3 million | $3.2 million | 2025-06 |
| Visiting Nurse Association of Greater St Louis | Health care | 501(c)(3) | 1995 | $3 million | $1.2 million | 2024-12 |
| Lydias House Inc | Housing and shelter | 501(c)(3) | 1995 | $2.9 million | $7.3 million | 2025-09 |
| St Marys Building Corporation | 501(c)(2) | 1972 | $2.9 million | $40.1 million | 2025-06 | |
| National Garden Clubs Incorporated | Environment | 501(c)(3) | 1953 | $2.9 million | $26.3 million | 2025-05 |
| South City Community School | Education | 501(c)(3) | 2010 | $2.9 million | $2.7 million | 2025-07 |
| Downtown Childrens Center | Human services | 501(c)(3) | 1979 | $2.9 million | $454,635 | 2025-06 |
| National Museum of Transportation | 501(c)(3) | 1952 | $2.8 million | $8.8 million | 2024-12 | |
| WDH Foundation-C4 | Environment | 501(c)(4) | 2014 | $2.8 million | $91.5 million | 2024-12 |
| Operating Engineers Local No 148 Health and Welfare Trust | 501(c)(9) | 1956 | $2.8 million | $5.8 million | 2024-12 | |
| St Louis Legacy Ice Foundation | Recreation and sports | 501(c)(3) | 2017 | $2.8 million | $54,138 | 2025-06 |
| American Institute for Respiratory Equity | Diseases, disorders and medical disciplines | 501(c)(3) | 2025 | $2.8 million | $1.5 million | 2024-12 |
| Optimist International Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1971 | $2.8 million | $15.7 million | 2025-09 |
| Ascension Care Management Insurance Holdings | Health care | 501(c)(3) | 2014 | $2.8 million | $318.4 million | 2024-12 |
| Beth Hamedrosh Hagodol Cemetery Association | 501(c)(13) | 1977 | $2.8 million | $19.7 million | 2026-07 | |
| Missouri Organizing and Voter Engagement Action | Civil rights, social action and advocacy | 501(c)(4) | 2019 | $2.7 million | $1.8 million | 2024-12 |
| Missouri Society of Certified Public Accountants | 501(c)(6) | 1981 | $2.7 million | $4.6 million | 2025-06 | |
| Missouri Center for Public Health Excellence | Health care | 501(c)(3) | 2014 | $2.7 million | $1.1 million | 2025-12 |
| Deaf Empowerment Awareness Foundation Inc | Human services | 501(c)(3) | 2008 | $2.7 million | $2.4 million | 2025-12 |
| Ascension Providence Foundation | Human services | 501(c)(3) | 1994 | $2.7 million | $10.4 million | 2025-06 |
| Safe Connections | Human services | 501(c)(3) | 1976 | $2.7 million | $2.1 million | 2025-12 |
| Materials Technology Institute Inc | 501(c)(6) | 1978 | $2.7 million | $4.2 million | 2025-12 | |
| La Salle Charter Schools Inc | Education | 501(c)(3) | 2015 | $2.7 million | $698,171 | 2023-06 |
| Support Innovations Inc | Human services | 501(c)(3) | 2000 | $2.7 million | $4.9 million | 2024-12 |
| Applied Scholastics International | Education | 501(c)(3) | 1993 | $2.7 million | $712,038 | 2024-12 |
| St Louis Gymnastic Centre | 501(c)(3) | 1975 | $2.7 million | $3.2 million | 2025-07 | |
| Freedom Community Center | Community improvement and capacity building | 501(c)(3) | 2021 | $2.6 million | $2 million | 2025-06 |
| Home Builders Association of St Louis and Eastern Missouri | 501(c)(6) | 1942 | $2.6 million | $4.1 million | 2025-10 | |
| Unlocked Labs | Crime and legal-related | 501(c)(3) | 2017 | $2.6 million | $2 million | 2025-12 |
| United Association of Journeymen & Apprentice of the Plumbing & Pipe | 501(c)(5) | 1941 | $2.6 million | $7.7 million | 2025-12 | |
| Gateway Housing First Inc | Human services | 501(c)(3) | 2015 | $2.6 million | $2.4 million | 2025-06 |
By cause in Saint Louis, MO
- Philanthropy, voluntarism and grantmaking foundations 1,432
- Education 770
- Human services 608
- Religion-related 523
- Arts, culture and humanities 425
- Community improvement and capacity building 298
- Health care 293
- Recreation and sports 222
- Youth development 186
- Housing and shelter 152
- Mental health and crisis intervention 103
- Public and societal benefit 87
- Animal-related 84
- Crime and legal-related 66
- Diseases, disorders and medical disciplines 64
- Environment 55
- Employment 54
- Civil rights, social action and advocacy 47
- Food, agriculture and nutrition 46
- International, foreign affairs and national security 43
- Mutual and membership benefit 39
- Public safety, disaster preparedness and relief 37
- Medical research 20
- Science and technology 19
- Social science 6
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.